|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Ca. 2.5 Ga TTG rocks in the western Alxa Block and their implications显示文摘The Alxa Block is considered part of the North China Craton, but the unambiguous Archean basement has not been reported. In this study, we present the first evidence of the Neoarchean rocks in the Beidashan area of the western Alxa Block. The petrographic and geochemical data show that these rocks are granodiorite with TTG (tonalite-trondhjemite-granodiorite) characteristics. Zircon U-Pb dating gave an age of 2522±30 Ma for the magmatic core and 2496±11 Ma for the metamorphic recrystallized rim. The near-identical age between the Latest Neoarchean magmatism and the high-grade metamorphism shows that these features were related to the same Latest Neoarchean-Earliest Paleoproterozoic tectonothermal event. The age-corrected Hf (t) value is mainly between 0.4 and 4.9. The two-stage zircon Hf model age ranges from 2.7 to 3.0 Ga, suggesting that the Mesoarchean- Neoarchean (2.7-3.0 Ga) juvenile crust was reworked at the end of the Neoarchean in the western Alxa Block. These data suggest that the western Alxa Block experienced a Mesoarchean-Neoarchean crust growth and Latest Neoarchean-Earliest Paleoproterozoic tectonothermal event similar to the North China Craton. | GONG JiangHua ZHANG JianXin YU ShengYao LI HuaiKun HOU KeJun | 2012 | Chinese Science Bulletin2012，57，31： | 21 |
| 2 | Kaempferol protects ethanol-induced gastric ulcers in mice via pro-inflammatory cytokines and NO显示文摘胃的溃疡(GU ) 是在全世界影响许多人的普通病理。过多的白酒消费是 GU 的主要原因之一;然而,仍然有为 GU 的预防或治疗的有效的药的缺乏。在这研究,我们在老鼠把保护的效果和 kaempferol (KAE ) 的可能的机制与尖锐导致乙醇的损害作比较到胃的 mucosa。Fasted 老鼠口头上地被给车辆(0.9% 盐) , omeprazole (20 mg/kg ) ,或为在在由有绝对乙醇(10 ml/kg ) 的挑战的 GU 模型的建立以前的不同试验性的集合的 1 h 的 KAE (40, 80,或 160 mg/kg ) 。动物是 euthanized 在乙醇吸入以后的 1 h,和他们的血浆和胃纸巾服从于进一步的检查。宏观、显微镜的损害,和免疫学的和生物化学的参数被观察。发炎的效果用下列指示物被调查:肿瘤坏死因素 --(TNF-) , interleukin-1 (IL-1 ) , IL-6, myeloperoxidase (军邮局) ,和氮的氧化物(没有) 。结果证明 KAE 显著地减少了溃疡索引,增加了预防索引,完全保护了 mucosa 免受损害,和保存胃的 mucosal glycoprotein 的伤害。KAE 减少了军邮局活动和支持 inflammatory cytokine (TNF- ,和 IL-1 ) 铺平,并且没改进层次。KAE 的 gastroprotective 活动可能被归因于胃的有粘液的 glycoproteins 层次的保藏,这样由禁止嗜中性的累积和军邮局活动,调整支持 inflammatory cytokines 的层次,并且不改进生产。 | Qinchen Li Xinxin Hu Yanhan Xuan Jianghua Ying Yujia Fei Jielu Rong Yong Zhang Jian Zhang Chunyan Liu Zheng Liu | 2018 | Acta Biochimica et Biophysica Sinica2018，50，3： | 18 |
| 3 | The China Multi-Model Ensemble Prediction System and Its Application to Flood-Season Prediction in 2018显示文摘Multi-model ensemble prediction is an effective approach for improving the prediction skill short-term climate prediction and evaluating related uncertainties. Based on a combination of localized operation outputs of Chinese climate models and imported forecast data of some international operational models, the National Climate Center of the China Meteorological Administration has established the China multi-model ensemble prediction system version 1.0 (CMMEv1.0) for monthly-seasonal prediction of primary climate variability modes and climate elements. We verified the real-time forecasts of CMMEv1.0 for the 2018 flood season (June-August) starting from March 2018 and evaluated the 1991-2016 hindcasts of CMMEv1.0. The results show that CMMEv1.0 has a significantly high prediction skill for global sea surface temperature (SST) anomalies, especially for the El Nino-Southern Oscillation (ENSO) in the tropical central-eastern Pacific. Additionally, its prediction skill for the North Atlantic SST triple (NAST) mode is high, but is relatively low for the Indian Ocean Dipole (IOD) mode. Moreover, CMMEv1.0 has high skills in predicting the western Pacific subtropical high (WPSH) and East Asian summer monsoon (EASM) in the June-July-August (JJA) season. The JJA air temperature in the CMMEv1.0 is predicted with a fairly high skill in most regions of China, while the JJA precipitation exhibits some skills only in northwestern and eastern China. For real-time forecasts in March-August 2018, CMMEv1.0 has accurately predicted the ENSO phase transition from cold to neutral in the tropical central-eastern Pacific and captures evolutions of the NAST and IOD indices in general. The system has also captured the main features of the summer WPSH and EASM indices in 2018, except that the predicted EASM is slightly weaker than the observed. Furthermore, CMMEv1.0 has also successfully predicted warmer air temperatures in northern China and captured the primary rainbelt over northern China, except that it predicted much more precipitation in the middle and lower reaches of the Yangtze River than observation. | Hong-Li REN Yujie WU Qing BAO Jiehua MA Changzheng LIU Jianghua WAN Qiaoping LI Xiaofei WU Ying LIU Ben TIAN Joshua-Xiouhua FU Jianqi SUN | 2019 | Journal of Meteorological Research2019，33，3： | 16 |
| 4 | High temperature and high pressure rheological properties of high-density water-based drilling fluids for deep wells显示文摘To maintain tight control over rheological properties of high-density water-based drilling fluids, it is essential to understand the factors influencing the rheology of water-based drilling fluids. This paper examines temperature effects on the rheological properties of two types of high-density water-based drilling fluids (fresh water-based and brine-based) under high temperature and high pressure (HTHP) with a Fann 50SL rheometer. On the basis of the water-based drilling fluid systems formulated in laboratory, this paper mainly describes the influences of different types and concentration of clay, the content of a colloid stabilizer named GHJ-1 and fluid density on the rheological parameters such as viscosity and shear stress. In addition, the effects of aging temperature and aging time of the drilling fluid on these parameters were also examined. Clay content and proportions for different densities of brine-based fluids were recommended to effectively regulate the rheological properties. Four rheological models, the Bingham, power law, Casson and H-B models, were employed to fit the rheological parameters. It turns out that the H-B model was the best one to describe the rheological properties of the high-density drilling fluid under HTHP conditions and power law model produced the worst fit. In addition, a new mathematical model that describes the apparent viscosity as a function of temperature and pressure was established and has been applied on site. | Wang Fuhua Tan Xuechao Wang Ruihe Sun Mingbo Wang Li Liu Jianghua | 2012 | Petroleum Science2012，9，3： | 8 |
| 5 | Multiple Components are Integrated to Determine Leaf Complexity in Lotus japonicus显示文摘Transcription factors and phytohormones have been reported to play crucial roles to regulate leaf complexity among plant species. Using the compound-leafed species Lotus japonicus, a model legume plant with five visible leaflets, we characterized four independent mutants with reduced leaf complexity, proliferating floral meristem (pfm), proliferating floral organ-2 (pfo-2), fused leaflets1 (ful1) and umbrella leaflets (uml), which were further identified as loss-of-function mutants of Arabidopsis orthologs LEAFY (LFY ), UNUSUAL FLORAL ORGANS (UFO), CUP-SHAPED COTYLEDON 2 (CUC2) and PIN-FORMED 1 (PIN1), respectively. Comparing the leaf development of wild-type and mutants by a scanning electron microscopy approach, leaflet initiation and/or dissection were found to be affected in these mutants. Expression and phenotype analysis indicated that PFM/LjLFY and PFO/LjUFO determined the basipetal leaflet initiation manner in L. japonicus. Genetic analysis of ful1 and uml mutants and their double mutants revealed that the CUC2-like gene and auxin pathway also participated in leaflet dissection in L. japonicus, and their functions might influence cytokinin biogenesis directly or indirectly. Our results here suggest that multiple genes were interplayed and played conserved functions in controlling leaf complexity during compound leaf development in L. japonicus. | Zhenhua Wang Jianghua Chen Lin Weng Xin Li Xianglin Cao Xiaohe Hu Da Luo Jun Yang | 2013 | Journal of Integrative Plant Biology2013，55，5： | 6 |
| 6 | Classification of cultivated Chinese medicinal plants based on fractal theory and gray level co-occurrence matrix textures显示文摘 | ZHENG Shudan ZHENG Jianghua SHI Minghui GUO Baolin SEN Bati SUN Zhiqun JIA Xiaoguang LI Xiaojin | 2014 | 遥感学报2014，18，4： | 5 |
| 7 | Fishery Biology of Jumbo Flying Squid Dosidicus gigas off Costa Rica Dome显示文摘The jumbo flying squid(Dosidicus gigas) population was surveyed with the help of Chinese squid jigging vessels off the Costa Rica Dome(4°–11°N, 90°–100°W) in 2009 and 2010. The daily catch of D. gigas in the two survey cruises ranged from 0 to 5.5 t and was mostly obtained from the areas bounded by 6°–9°N and 91°–94°W and by 6°30′–7°30′N and 96°–97°W. The sea surface temperature in the areas yielding the most catch ranged from 27.5 to 29℃. The sex ratio of the total catch was 3.75:1(female: male). The mantle length of the squid ranged from 211 to 355 mm(male) and from 204 to 429 mm(female) with an average of 297.9 and 306.7 mm, respectively. In the relationship of the mantle length(mm) and body weight(g) of the squid, there was no significant difference between sexes. The female and male were at a similar maturity, and most individuals are maturing or have matured with a few females being spent. The size(mantle length) and age at the first sexual maturity were 297 mm and 195 d in females, and less than 211 mm and 130 d in males, respectively. Most of the sampled stomachs(70.6%) had no food remains. The major preys of the squids were fish, cephalopods and crustaceans, with the most abundant Myctophum orientale and D. gigas. The preys in more than 65% of the non-empty sampled stomachs evidenced the cannibalism of D. gigas. The results improved current understanding of the fishery biology of D. gigas off the Costa Rica Dome, which may facilitate the assessment and management of relative fishery resources. | CHEN Xinjun LI Jianghua LIU Bilin LI Gang LU Huajie | 2014 | Journal of Ocean University of China2014，13，3： | 4 |
| 8 | Food synthetic biology-driven protein supply transition: From animal-derived production to microbial fermentation显示文摘Animal-derived protein production is one of the major traditional protein supply methods,which continues to face increasing challenges to satisfy global needs due to population growth,augmented individual protein consumption,and aggravated environmental pollution.Thus,ensuring a sustainable protein source is a considerable challenge.The emergence and development of food synthetic biology has enabled the establishment of cell factories that effectively synthesize proteins,which is an important way to solve the protein supply problem.This review aims to discuss the existing problems of traditional protein supply and to elucidate the feasibility of synthetic biology in the process of protein synthesis.Moreover,using artificial bioengineered milk and artificial bioengineered eggs as examples,the progress of food protein supply transition based on synthetic biology has been systematically summarized.Additionally,the future of food synthetic biology as a potential source of protein has been also discussed.By strengthening and innovating the application of food synthetic biology technologies,including genetic engineering and high-throughput screening methods,the current limitations of artificial foods for protein synthesis and production should be addressed.Therefore,the development and industrial production of new food resources should be explored to ensure safe,high-quality,and sustainable global protein supply. | Yanfeng Liu Xiaomin Dong Bin Wang Rongzhen Tian Jianghua Li Long Liu Guocheng Du Jian Chen | 2021 | Chinese Journal of Chemical Engineering2021，34，2： | 4 |
| 9 | A review of the application of nanoparticles in the diagnosis and treatment of chronic kidney disease显示文摘Chronic kidney disease(CKD)poses a great burden to global public health as current therapies are generally ineffective.Early detection and effective therapy are crucial for the future prevention and progression of CKD.Nanoparticles(NPs)vary by particle size,charge,shape and the density of targeting ligands and are associated with enhancement of the pharmacokinetic properties,targetability,or the bioavailability of drugs.Thus,the emergence of NPs in medicine has provided novel solutions to the potential diagnosis and treatment of CKD.This review describes the current experimental research,clinical applications of NPs,the current challenges,and upcoming opportunities in the diagnosis and treatment of CKD. | Yanhong Ma Fanghao Cai Yangyang Li Jianghua Chen Fei Han Weiqiang Lin | 2020 | Bioactive Materials2020，5，3： | 3 |
| 10 | Identification of transporter proteins for PQQ-secretion pathways by transcriptomics and proteomics analysis in Gluconobacter oxydans WSH-003显示文摘Pyrroloquinoline quinone (PQQ ) 在细菌与脱氢酶在联合作为一个氧化还原作用余因子起一个重要作用。这些脱氢酶为生物工学工业在重要底层的氧化起关键作用,例如维生素 C 生产。当 PQQ 基因的生合成广泛地被学习了时, PQQ 运输机制仍然保持不清楚。此处,我们使用了定序在 Gluconobacter oxydans WSH-003 的工业紧张调查 pqqB overexpression 的效果的两二维的荧光差别胶化电气泳动双人脚踏车团 spectrometry 和 RNA。我们鉴别了 73 差别表示了蛋白质, 99 差别表示了基因,其一个多数与氧化减小有关并且由基因本体论分析搬运过程。我们也描述了对源于 pqqB overexpression 的增加的 PQQ 层次作出回应的几个通常认为的候选人受动器。而且,量的 PCR 被用来在生产紧张的不同 PQQ 之中验证五通常认为的 PQQ 运输基因,并且结果证明 ompW, B932_1930 和 B932_2186 是处于所有条件的 upregulated。当时,三基因在 G 是过去表示的。oxydans WSH-003 和 PQQ 生产被检测。结果显示出 B932_1930 (transporter ) 的那细胞外的 PQQ, overexpression 拉紧的 B932_2186 (ABC transporter permease ) 被 1.77 褶层和 1.67 褶层分别地提高。结果建议 PqqB, B932_1930 和 B932_2186 编码的蛋白质可能提高 PQQ 分泌物过程。 | Hui Wan Yu Xia Jianghua Li Zhen Kang Jingwen Zhou | 2017 | Frontiers of Chemical Science and Engineering2017，11，1： | 3 |
| 11 | Study of high pressure sintering behavior of CBN composites starting with CBN-Al mixtures显示文摘Cubic boron nitride(CBN) composites starting with CBN-Al mixtures were sintered on WC-16 wt%Co substrate under static high pressure of 5.0 GPa at temperatures of 800 to 1 400℃for 30 min.Vickers hardness of the sintered samples increased with increasing CBN content and the highest hardness of 32.7 GPa was achieved for the CBN-5 wt%Al specimens sintered at 1 400℃.The reactions between CBN and Al started to occur at about 900℃and the reaction products strongly depended on the Al content,sintering temperature and Co diffused from the substrates according to the x-ray diffraction(XRD) observations.The CBN composite sintered at 1 200℃from a CBN-15 wt%Al mixture showed the best cutting performance. | Li Yongjun Li Sicheng Lv Ran Qin Jiaqian Zhang Jian Wang Jianghua Wang Fulong Kou Zili He Duanwei (Institute of Atomic and Molecular Physics,Sichuan University,Chengdu 610065,China) | 2008 | 金刚石与磨料磨具工程2008，28，S1： | 3 |
| 12 | AN M/G/1 RETRIAL QUEUE WITH SECOND MULTI-OPTIONAL SERVICE,FEEDBACK AND UNRELIABLE SERVER显示文摘有二阶段的服务和反馈的一个 M/G/1 再审队列在这篇论文被学习,在服务者在服务期间服从于开始的失败和故障的地方。Primarycustomers 根据泊松进程得到系统在里面,并且如果服务器在到达之上是可得到的,他们将立即收到服务。否则,他们将进入一条再审轨道并且根据 first-come-first-served (FCFS ) 在轨道被排队纪律。Customersare 允许在特别时间畏缩不前并且背信。所有顾客要求第一种“必要”的服务,而仅仅他们的一些要求第二种“多可选”的服务。再审时间,服务时间和服务者的修理时间都是任意地分布式的,这被假定。为系统稳定性的 Thenecessary 和足够的状况被导出。用一个增补可变方法,一些排队和系统的可靠性措施的不变的解决方案被获得。 | Li Jianghua Wang Jinting | 2006 | Applied Mathematics(A Journal of Chinese Universities)2006，21，3： | 2 |
| 13 | Experimental Study of the Effect of Autonomic Nervous System on the Transmural Dispersion of Ventricular Repolarization under Acute Myocardial Ischemia in Vivo显示文摘Summary: The effect of the autonomic nerves on the transmural dispersion of ventricular repolarization (TDR) under acute myocardial ischemia in intact canine was investigated. Using the monophasic action potential (MAP) recording technique, MAPs of the epicardium (Epi), midmyocardium (Mid) and endocardium (Endo) were recorded simultaneously by specially designed plunge-needle electrodes at the left ventricular free wall under acute myocardial ischemia in 12 open-chest dogs. MAPD 90 and TDR among three myocardial layers as well as the incidence of the early afterdepolarization (EAD) before autonomic nervous stimulation and during autonomic nervous stimulation were compared. It was found that 10 min after acute myocardial ischemia, TDR was increased from 55±8 ms to 86±15 ms during sympathetic stimulation (P<0.01). The TDR (53±9 ms) during parasympathetic stimulation was not significantly different from that of the control (55±8 ms) (P>0.05). The EAD was elicited in the Mid of 2 dogs (16 %) 10 min after acute myocardial ischemia, but the EAD were elicited in the Mid of 7 dogs (58 %) during sympathetic stimulation (P<0.01). It was concluded that: (1) Sympathetic stimulation can increase the transmural dispersion of repolari-zation and induce early afterdepolarizations in the Mid under acute myocardial ischemia, which provide the opportunity for the ventricular arrhythmia developing; (2) Parasympathetic stimulation has no significant effect on the transmural dispersion of repolarization under myocardial ischemia. | ZHANG Cuntai(张存泰) XU Dawen(徐大文) LI Yang(李泱) LIU Nian(刘念) ZHONG Jianghua(钟江华) WANG Lin(王琳) LU Zaiying(陆再英) | 2002 | Journal of Huazhong University of Science and Technology(Medical Sciences)2002，22，2： | 2 |
| 14 | Metabolic engineering of Escherichia coli for the production of Lacto-N-neotetraose(LNnT)显示文摘Lacto-N-neotetraose(LNnT),one of the most important human milk oligosaccharides,can be used as infants’food addi-tives.Nowadays,extraction,chemical and biological synthesis were utilized to obtain LNnT,while these methods still face some problems such as low yield and high cost.The aim of current work is to construct a de novo biosynthesis pathway of LNnT in E.coli K12 MG1655.The lgtA and lgtB were first expressed by a plasmid,resulting in a LNnT titer of 0.04 g/L.To improve the yield of LNnT on substrate lactose,lacZ and lacI were knocked out,and lacY was over-expressed.As a result,the yield of LNnT on lactose increased from 0.01 to 0.09 mol/mol,and the titer of LNnT elevated to 0.41 g/L.In addition,the pathway was regulated using the titer of Lacto-N-triose II(LNTII)as a measure,and obtained a high titer strain of LNnT for 1.04 g/L.Finally,the gene expressions were fine-tuned,the titer of LNnT reached 1.2 g/L,which was 93%higher than the control strain,and the yield on lactose reached 0.28 mol/mol.The engineering strategy of pathway construction and modulation used in this study is applicable to facilitate the microbial production of other metabolites in E.coli. | Wei Zhang Zhenmin Liu Mengyue Gong Nan Li Xueqin Lv Xiaomin Dong Yanfeng Liu Jianghua Li Guocheng Du Long Liu | 2021 | Systems Microbiology and Biomanufacturing2021，1，3： | 2 |
| 15 | Recent advances and challenges in microbial production of human milk oligosaccharides显示文摘Human milk oligosaccharides(HMOs)are one of the major differences between livestock milk and human milk,and the prebiotic functions of HMOs have been verified through in vitro and clinical trials.The most abundant HMOs include 2′-fucysollactose(2′-FL),3-fucosyllactose(3-FL),lacto-N-neotetraose(LNnT)and lacto-N-tetraose(LNT);their application and synthesis have attracted wide attentions.In recent years,the biotechnological production of 2′-FL,3-FL,LNnT and LNT have emerged based on techniques such as whole-cell catalysis and fermentation.In particular,the development of metabolic engineering and synthetic biology methods and strategies have facilitated efficient biosynthesis of these HMOs.However,these advantages have not been systematically reviewed yet.In this review,we first discuss the structures and applications of HMOs;secondly,strategies of microbial synthesis of the most abundant 2′-FL,3-FL,LNnT and LNT are summarized and compared.Finally,challenges and perspectives of efficient microbial production of HMOs as well as strategies for overcoming the challenges are discussed.This review reveals the whole picture of recent development in HMOs microbial synthesis and can further facilitate the understanding of limiting factors,and further propose a few directions to promote the development of efficient production hosts. | Jieying Deng Xueqin Lv Jianghua Li Guocheng Du Jian Chen Long Liu | 2021 | Systems Microbiology and Biomanufacturing2021，1，1： | 2 |
| 16 | Current advances in design and engineering strategies of industrial enzymes显示文摘Enzymes are considered as functional proteins,also known as biocatalysts,which are required for normal cellular function.The commercial production of enzymes with distinct features always remains the top priority of researchers for industrial biocatalysis.However,the insufficient yield,low stability,low activity,formation of by-products,complex purification pro-cess,and many other factors are challenging for the enzyme production industry.Novel advancements in protein engineering,especially the combination of multidisciplinary techniques including post-translational enzyme modification,structured assisted protein tailoring and computational modeling approaches,open a new horizon to more efficient production of bio-catalysts.In this review,we focus on the development process of enzyme modification design strategies,such as rational design,semi-rational design and de novo design.Selected examples for each strategy,which are particularly useful for novel enzyme design,are given.We hope this review is helpful for the development of biocatalysts for industrial application. | Tanatarov Dinmukhamed Ziyang Huang Yanfeng Liu Xueqin Lv Jianghua Li Guocheng Du Long Liu | 2021 | Systems Microbiology and Biomanufacturing2021，1，1： | 2 |
| 17 | Unusual relationship between impact toughness and grain size in a high-manganese steel显示文摘The high-manganese steels are important structural materials,owing to their excellent toughness at low temperatures.However,the microstructural causes for their unusual properties have not adequately been understood thus far.Here,we report a reversal relationship between impact toughness and grain size in a high-manganese steel and its unrevealed microscopic mechanisms,which result in an excellent low-temperature toughness of the steel.Our investigations show that with increasing grain size the impact toughness of the steel can be improved drastically,especially at low-temperatures.Advanced electron microscopy characterization reveals that the enhanced impact toughness of the coarse-grained steel is attributed to the twinning induced plasticity and transformation induced plasticity effects,which produce large quantities of deformation twins,ε_(hcp)-martensite andα'_(bcc)-martensite.Inversely,in the fine-grained steels,the formation of deformation twins and martensite is significantly inhibited,leading to the decrease of impact toughness.Microstructural characterizations also indicate thatε_(hcp)-martensite becomes more stable thanα'_(bcc)-martensite with decreasing temperature,resulting in characteristic microstructures in the coarse-grained samples after impact deformation at liquid nitrogen temperature.In the coarse-grained samples under impact deformation at-80℃,ε_(hcp)-martensite transformation,α'_(bcc)-martensite transformation and deformation twinning all occur simultaneously,which greatly improves the toughness of the steel. | Pan Xie Shucheng Shen Cuilan Wu Jiehua Li Jianghua Chen | 2021 | Journal of Materials Science & Technology2021，，30： | 2 |
| 18 | Effects of larval host plants on over-wintering preparedness and survival of the cotton bollworm, Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae)显示文摘 | Zhudong Liu Peiyu Gong Kujun Wu Wei Wei Jianghua Sun Dianmo Li | 2007 | Journal of Insect Physiology2007，，10： | 1 |
| 19 | Tacrolimus as a ster- oid-sparing agent for adults with steroid-dependent minimal change nephrotic syndrome 显示文摘 | Xiayu Li Heng Li Jianghua Chen | 2008 | Nephrol Dial Transplant2008，23，： | 1 |
| 20 | Recent advances in engineered nanomaterials for acute kidney injury theranostics显示文摘Acute kidney injury(AKI),has become the focus of increasing attention due to its high risk of death.The early diagnosis and treatment of AKI significantly reduce the risk of renal tissue damage and kidney dysfunction.However,the efficient early diagnosis and treatment approach for AKI remains a challenge.AKI screening via precise nanomaterial theranostics is a new alternative approach.This study summarizes the recent advances in functional nanomaterials in the early detection and treatment of AKI.The challenges and problems in the use of nanomaterials for AKI in clinical applications are also discussed.It is anticipated that highlighting these new advances will lay the foundation for further translational research on the promising application of nanomaterials for AKI. | Lefeng Wang Yunjing Zhang Yangyang Li Jianghua Chen Weiqiang Lin | 2021 | Nano Research2021，14，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员