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| 1 | Different Transcription Profiles of SOCS-3,ob and IGF-I Genes and their Possible Correlations in Obese and Lean Pigs显示文摘猪品种在胖免职和肌肉发展能力有重要差别。然而,在这些差别后面的分子的机制仍然是 unknown.Inthis 学习,三候选人基因的表示模式,压制或表明 3 的 cytokine ( SOCS-3 ),肥胖( ob )和像胰岛素的生长因素我( IGF-I ),它涉及脂肪质的新陈代谢或肌肉开发,被分析。全部的 RNA 从 8-month-old Bamei 的背面的下的脂肪质的组织和 longissimus 被提取, Largewhite pigs.Semiquantitative reversetranscription 聚合酶链反应被用来在肌肉组织在脂肪质的组织,和 SOCS-3 和 IGF-I 基因决定 SOCS-3and ob 基因的表示层次。结果证明在脂肪质的组织, SOCS-3 的表示水平在 Bamei 是显著地更高的(肥胖) 猪比那在 Largewhite (瘦) 猪(P<0.01 ) 。然而,在肌肉组织,它在 Largewhite 猪(P<0.01 ) 比那是显著地更低的 inBamei。而且, SOCS-3 的表示断然在肌肉组织在脂肪质的组织和 IGF-I 的被相关到 ob 的。这些调查结果建议在 SOCS-3 基因表达的差别铺平在脂肪质并且肌肉纸巾,在在肌肉组织的 SOCS-3 和 IGF-I 之间的在在脂肪质的组织的 SOCS-3 和 ob 之间的关系,和那,可能贡献在肥胖、瘦的猪之间的不同胖免职和肌肉发展能力。 | Jiangwei WU Bo WANG Haowei ZHANG Taiyong YU Gongshe YANG | 2007 | Acta Biochimica et Biophysica Sinica2007，39，4： | 6 |
| 2 | Characterization of miRNomes in Acute and Chronic Myeloid Leukemia Cell Lines显示文摘Myeloid leukemias are highly diverse diseases and have been shown to be associated with microRNA(miRNA) expression aberrations. The present study involved an in-depth miRNome analysis of two human acute myeloid leukemia(AML) cell lines, HL-60 and THP-1, and one human chronic myeloid leukemia(CML) cell line, K562, via massively parallel signature sequencing. mRNA expression profiles of these cell lines that were established previously in our lab facilitated an integrative analysis of miRNA and mRNA expression patterns. miRNA expression profiling followed by differential expression analysis and target prediction suggested numerous miRNA signatures in AML and CML cell lines. Some miRNAs may act as either tumor suppressors or oncomiRs in AML and CML by targeting key genes in AML and CML pathways. Expression patterns of cell type-specific miRNAs could partially reflect the characteristics of K562, HL-60 and THP-1 cell lines, such as actin filament-based processes, responsiveness to stimulus and phagocytic activity. miRNAs may also regulate myeloid differentiation, since they usually suppress differentiation regulators. Our study provides a resource to further investigate the employment of miRNAs in human leukemia subtyping, leukemogenesis and myeloid development. In addition, the distinctive miRNA signatures may be potential candidates for the clinical diagnosis, prognosis and treatment of myeloid leukemias. | Qian Xiong Yadong Yang Hai Wang Jie Li Shaobin Wang Yanming Li Yaran Yang Kan Cai Xiuyan Ruan Jiangwei Yan Songnian Hu Xiangdong Fang | 2014 | Genomics, Proteomics & Bioinformatics2014，12，2： | 6 |
| 3 | Cyclometalated platinum(Ⅱ) complexes with sterically bulky camphor-derived groups as β-diketonate ancillary ligand:a new route to efficiently reducing π-π interactions and Pt-Pt interactions显示文摘A new series of mono-cyclometalated square planar platinum(Ⅱ) complexes have been synthesized and the single-crystal X-ray structures of complex 1 and 2 have been determined.The complexes have the general formula ppyPt(O^O),where ppy is 2-phenylpyridyl,and O^O is β-diketonate ancillary ligands with the acyl substituent group in position 3 of(D)-(+)-camphor.Although,like the many Pt(Ⅱ) complexes with square-planar geometry,these complexes have plane stacking modes in crystal structure,the sterically bulky camphor-derived groups compel extensive slipping of the molecular stacking planes,resulting in the negligible overlapping of the aromatic ring fragments between molecules and the considerable Pt-Pt distance.The resolved spectra and a little shifted emission in solid state of complexes show that there is significant reduction of π-π interactions and Pt-Pt interactions,and suggest these complexes may be good candidates for doped phosphorescent organic light emitting diodes(PhOLEDs) and even for nondoped PhOLEDs. | LUO KaiJun,XIE Yu,XU LingLing,WANG JiangWei,ZHANG LiFang & ZHAO KeQing College of Chemistry and Materials Science,Sichuan Normal University,Chengdu 610068,China | 2010 | Science China Chemistry2010，53，1： | 5 |
| 4 | The spatial variation of soil bacterial community assembly processes affects the accuracy of source tracking in ten major Chinese cities显示文摘Urban soils harbor billions of bacterial cells and millions of species.However,the distribution patterns and assembly processes of bacterial communities remain largely uncharacterized in urban soils.It is also unknown if we can use the bacteria to track soil sources to certain cities and districts.Here,Illumina MiSeq sequencing was used to survey soil bacterial communities from 529 random plots spanning 61 districts and 10 major cities in China.Over a 3,000 km range,community similarity declined with increasing geographic distance(Mantel r=0.62),and community composition was clustered by city(R^(2)=0.50).Within cities(<100 km),the aforementioned biogeographic patterns were weakened.Process analysis showed that homogenizing dispersal and dispersal limitation dominated soil bacterial assembly at small and large spatial scales,respectively.Accordingly,the probabilities of accurately tracking random soil sources to certain cities and districts were 90.0% and 66.7%,respectively.When the tested samples originated from cities that were more than 1,265 km apart,the soil sources could be identified with nearly 100% accuracy.Overall,this study demonstrates the strong distance-decay relationship and the clear geographic zoning of urban soil bacterial communities among cities.The varied importance of different community assembly processes at multiple spatial scales strongly affects the accuracy of microbial source tracking. | Teng Yang Yu Shi Jun Zhu Chang Zhao Jianmei Wang Zhiyong Liu Xiao Fu Xu Liu Jiangwei Yan Meiqing Yuan Haiyan Chu | 2021 | Science China(Life Sciences)2021，64，9： | 4 |
| 5 | Prediction-based Manufacturing Center Self-adaptive Demand Side Energy Optimization in Cyber Physical Systems显示文摘Cyber physical systems(CPS)recently emerge as a new technology which can provide promising approaches to demand side management(DSM),an important capability in industrial power systems.Meanwhile,the manufacturing center is a typical industrial power subsystem with dozens of high energy consumption devices which have complex physical dynamics.DSM,integrated with CPS,is an effective methodology for solving energy optimization problems in manufacturing center.This paper presents a prediction-based manufacturing center self-adaptive energy optimization method for demand side management in cyber physical systems.To gain prior knowledge of DSM operating results,a sparse Bayesian learning based componential forecasting method is introduced to predict24-hour electric load levels for specific industrial areas in China.From this data,a pricing strategy is designed based on short-term load forecasting results.To minimize total energy costs while guaranteeing manufacturing center service quality,an adaptive demand side energy optimization algorithm is presented.The proposed scheme is tested in a machining center energy optimization experiment.An AMI sensing system is then used to measure the demand side energy consumption of the manufacturing center.Based on the data collected from the sensing system,the load prediction-based energy optimization scheme is implemented.By employing both the PSO and the CPSO method,the problem of DSM in the manufacturing center is solved.The results of the experiment show the self-adaptive CPSO energy optimization method enhances optimization by 5%compared with the traditional PSO optimization method. | SUN Xinyao WANG Xue WU Jiangwei LIU Youda | 2014 | Chinese Journal of Mechanical Engineering2014，27，3： | 4 |
| 6 | Searching for the Nano-Hertz Stochastic Gravitational Wave Background with the Chinese Pulsar Timing Array Data ReleaseⅠ显示文摘Observing and timing a group of millisecond pulsars with high rotational stability enables the direct detection of gravitational waves(GWs).The GW signals can be identified from the spatial correlations encoded in the times-of-arrival of widely spaced pulsar-pairs.The Chinese Pulsar Timing Array(CPTA)is a collaboration aiming at the direct GW detection with observations carried out using Chinese radio telescopes.This short article serves as a“table of contents”for a forthcoming series of papers related to the CPTA Data Release 1(CPTA DR1)which uses observations from the Five-hundred-meter Aperture Spherical radio Telescope.Here,after summarizing the time span and accuracy of CPTA DR1,we report the key results of our statistical inference finding a correlated signal with amplitude logA_(c)=-14.4_(-2.8)^(+1.0)for spectral index in the range ofα∈[-1.8,1.5]assuming a GW background(GWB)induced quadrupolar correlation.The search for the Hellings–Downs(HD)correlation curve is also presented,where some evidence for the HD correlation has been found that a 4.6σstatistical significance is achieved using the discrete frequency method around the frequency of 14 n Hz.We expect that the future International Pulsar Timing Array data analysis and the next CPTA data release will be more sensitive to the n Hz GWB,which could verify the current results. | Heng Xu Siyuan Chen Yanjun Guo Jinchen Jiang Bojun Wang Jiangwei Xu Zihan Xue RNicolas Caballero Jianping Yuan Yonghua Xu Jingbo Wang Longfei Hao Jingtao Luo Kejia Lee Jinlin Han Peng Jiang Zhiqiang Shen Min Wang Na Wang Renxin Xu Xiangping Wu Richard Manchester Lei Qian Xin Guan Menglin Huang Chun Sun Yan Zhu | 2023 | Research in Astronomy and Astrophysics2023，23，7： | 3 |
| 7 | Atomic-scale mechanism of the θ’’→θ’ phase transformation in Al-Cu alloys显示文摘The phase transformation of θ’’→θ’ in an Al-5.7 Cu alloy was investigated by aberration-corrected scanning transmission electron microscopy, and the tranformation mode of θ’’→θ’ during aging treatment was clarified. In the presence of the θ’ phases, θ’ was found to be formed by in-situ transformation fromθ’’ with the same plate shape, size and broad faces. The transformation starts from multiple sites within the θ’ precipitate and the whole θ’ phase finally forms as the preferential θ’ sections grow and connect with each other. Antiphase domain boundaries are also found in some θ’ precipitates when the disregistry exists between different θ’ sections. | Zhenju Shen Qingqing Ding Chunhui Liu Jiangwei Wang He Tian Jixue Li Ze Zhang | 2017 | Journal of Materials Science & Technology2017，33，10： | 3 |
| 8 | Effects of cannabinoid receptor type 2 on endogenous myocardial regeneration by activating cardiac progenitor cells in mouse infarcted heart显示文摘Cannabinoid receptor type 2(CB2)activation is recently reported to promote proliferation of some types of resident stem cells(e.g.,hematopoietic stem/progenitor cell or neural progenitor cell).Resident cardiac progenitor cell(CPC)activation and proliferation are crucial for endogenous cardiac regeneration and cardiac repair after myocardial infarction(MI).This study aims to explore the role and possible mechanisms of CB2receptor activation in enhancing myocardial repair.Our results revealed that CB2receptor agonist AM1241 can significantly increase CPCs by c-kit and Runx1 staining in ischemic myocardium as well as improve cardiomyocyte proliferation.AM1241 also decreased serum levels of MDA,TNF-αand IL-6 after MI.In addition,AM1241 can ameliorate left ventricular ejection fraction and fractional shortening,and reduce fibrosis.Moreover,AM1241 treatment markedly increased p-Akt and HO-1 expression,and promoted Nrf-2 nuclear translocation.However,PI3K inhibitor wortmannin eliminated these cardioprotective roles of AM1241.In conclusion,AM1241 could induce myocardial regeneration and improve cardiac function,which might be associated with PI3K/Akt/Nrf2 signaling pathway activation.Our findings may provide a promising strategy for cardiac endogenous regeneration after MI. | WANG YaBin MA Sai WANG Qiang HU WenXing WANG DongJuan LI XiuJuan SU Tao QIN Xing ZHANG XiaoTian MA Ke CHEN JiangWei XIONG LiZe CAO Feng | 2014 | Science China(Life Sciences)2014，57，2： | 3 |
| 9 | The immunologic and hematopoietic profiles of mesenchymal stem cells derived from different sections of human umbilical cord显示文摘间充质的干细胞(MSC ) 广泛地在 allogeneic 干细胞移植被使用了。我们比较了 immunologic, MSC 的造血的特征源于整个人的脐的绳索(UC ) ,以及从 UC 的不同的节,包括羊膜的膜(AM ) ,沃顿的果冻(WJ ) ,和脐的容器(紫外) 。房间显型被流动 cytometry 检验。淋巴细胞转变测试和混合淋巴细胞反应被执行评估从 UC 导出的 MSC 的免疫调节的活动。cytokines 的 mRNA 表示被即时聚合酶链反应检测。造血的功能被文化 co MSC 学习, CD34 + 房间从绳索血孤立。我们的结果显示出包括 UC 与这四不同的节分开的那 MSC, WJ,紫外,并且 AM 有类似的生物特征。所有 MSC 有多系区别能力并且能区分进造骨细胞, adipocytes,和 chondrocytes。MSC 也以一种剂量依赖者方式禁止了 allogeneic T 房间的增长。cytokines 的相对 mRNA 表示被检验,并且结果显示出比 MSC 的有的更高的 interleukin-6 (IL6 ) , IL11,干细胞因素,和 FLT3 表示从 UC 的特定的节导出的那 UCMSC。当 co 有教养时, CD34 + 房间有高繁殖效率, MSC 源于 UC, UCMSC 在之中是最有效的喂层的不同的节。我们的学习证明 MSC 能与支持特征的类似的 immunomodulation 和造血作用从整个 UC 或 UC 的特定的节被孤立。 | Man Xu Bin Zhan Yuanlin Liu Jin Zhang Hongxia Sheng Rui Shi Li Liao Na Liu Jiangwei Hu Jun Wang Hongmei Ning Ting Liu Yi Zhang Hu Chen | 2014 | Acta Biochimica et Biophysica Sinica2014，46，12： | 3 |
| 10 | Inconsistent creep between dendrite core and interdendritic region under different degrees of elemental inhomogeneity in nickel-based single crystal superalloys显示文摘The creep inconsistency between dendrite core and interdendritic region is investigated in a nickel-based single crystal superalloy under 1373 K and 137 MPa.Two specimens with higher and lower degree of elemental inhomogeneity on dendritic structures are compared.For specimen with higher inhomogeneity,stronger segregation of refractory elements reinforces the local strength in dendrite core,but damages the strength in interdendritic region.Creep strain is accumulated faster in interdendritic region giving rise to promoted dislocation shearing inγphase,faster degradation of dislocation networks and facilitated topological inversion of rated structures.Although the segregation of refractory elements produces a high density of topologically close-packed(TCP)phase in dendrite core,faster accumulation of creep strain forms microcracks prior in interdendritic region that gives rise to final rupture of the specimen.In another specimen,increased solid solution time gives rise to overall reduced inhomogeneity.Creep inconsistency is relieved to show more uniform evolution of dislocation substructures and rafting between dendrite core and interdendritic region.The second specimen is ruptured by formation and extension of microcracks along TCP phase although the precipitation of TCP phase is relatively restricted under reduced inhomogeneity.Importantly,the balance of local strength between dendrite core and interdendritic region results in over 40%increase of creep rupture life of the second specimen. | Wanshun Xia Xinbao Zhao Liang Yue Quanzhao Yue Jiangwei Wang Qingqing Ding Hongbin Bei Ze Zhang | 2021 | Journal of Materials Science & Technology2021，，33： | 2 |
| 11 | Discrete twinning dynamics and size-dependent dislocation-to twin transition in body-centred cubic tungsten显示文摘Body-centred cubic(BCC) metals are known to have unstable intrinsic stacking faults and high resistance to deformation twinning, which can strongly influence their twinning behaviour. Though twinning mechanisms of BCC metals have been investigated for more than 60 years, the atomistic level dynamics of twinning remains under debate, especially regarding its impact on competition between twinning and slip. Here, we investigate the atomistic level dynamics of twinning in BCC tungsten(W) nanowires using in situ nanomechanical testing. Quantitative experimental studies directly visualize that deformation twins in W nanowires have a minimum size of six-layers and grow in increments of approximately three-layers at a time, in contrast to the layer-by-layer growth of deformation twins in face-centred cubic metals. These unique twinning dynamics induces a strong competition with ordinary dislocation slip,as exhibited by a size-dependent dislocation-to-twin transition in W nanowires, with a transition size of ~40 nm. Our work provides physical insight into the dynamics of twinning at the atomic level, as well as a size-dependent dislocation-twinning competition, which have important implications for the plastic deformation in a broad class of BCC metals and alloys. | Jiangwei Wang Anik H.M.Faisal Xiyao Li Youran Hong Qi Zhu Hongbin Bei Ze Zhang Scott X Mao Christopher R.Weinberger | 2022 | Journal of Materials Science & Technology2022，，11： | 2 |
| 12 | The influence of total ionizing dose on the hot carrier injection of 22 nm bulk nFinFET显示文摘We investigate the hot carrier injection effect(HCI)and how X-ray radiation impacts the HCI of 22-nm nFinFETs as a function of device geometry and irradiation bias conditions in this paper.In the HCI test,the degradation of threshold voltage and saturation current decreases with the increase of fin number,which means that HCI weakens when the fin number increases.The reason is attributed to the coupling effect between fins.Moreover,irradiation is shown to weaken the degradation during the subsequent hot carrier test.The influence of irradiation on HCI is more obvious with ON bias than that of OFF bias and transmission gate bias.It is supposed that the Si–H bonds can be broken by irradiation before the HCI test,which is one reason for the irradiation influence on HCI.Besides,trapped charges are generated in the shallow trench isolation by the radiation,which could reduce the channel electric field,and then weaken the HCI. | Baoshun Wang Jiangwei Cui Qi Guo Qiwen Zheng Ying Wei Shanxue Xi | 2020 | Journal of Semiconductors2020，41，12： | 2 |
| 13 | Promoting nitric oxide electroreduction to ammonia over electron-rich Cu modulated by Ru doping显示文摘Electrocatalytic nitric oxide(NO)reduction is a promising strategy to produce ammonia.Developing a facile approach to synthesize efficient catalysts with enhanced NO electroreduction performance is highly desirable.Here,a series of Ru-doped Cu materials are constructed through in situ electroreduction of corresponding metal hydroxides.The optimized Ru_(0.05)Cu_(0.95)exhibits superior electrocatalytic performance for ammonia synthesis by using NO/Ar(1/4,n/n)as the feedstocks(Faradaic efficiency:64.9%,yield rate:17.68μmol cm^(-2)h^(-1)),obviously outperforming Cu counterpart(Faradaic efficiency:33.0%,yield rate:5.73μmol cm^(-2)h^(-1)).Electrochemical in situ Fourier transform infrared(FTIR)spectroscopy and online differential electrochemical mass spectrometry(DEMS)are adopted to detect intermediates and unveil the possible reaction pathway.The downshift of the Cu d-band center induced by Ru doping facilitates the rate-limiting hydrogenation step and decreases the desorption energy of NH_(3),leading to high Faradaic efficiency and yield of ammonia. | Jiangwei Shi Changhong Wang Rong Yang Fanpeng Chen Nannan Meng Yifu Yu Bin Zhang | 2021 | Science China Chemistry2021，64，9： | 2 |
| 14 | Study of the failure mechanism of an epoxy coating system under high hydrostatic pressure显示文摘 | Ying Liu Jiangwei Wang Li Liu Ying Li Fuhui Wang | 2013 | Corrosion Science2013，，： | 1 |
| 15 | Molec- ular cloning and characterization of a SID-I-LIKE gene in Plutella xylostella 显示文摘 | Wang Huidong Gong Liang Qi Jiangwei | 2014 | Arch Insect Biochem2014，87，3： | 1 |
| 16 | Biodegradable microparticles and fiber fabrics for delivery of cisplatin to treat c6 glioma in vitro显示文摘 | XIE Jiangwei TAN Ruoshan WANG C H | 2008 | J Biomed Mater Res:Part A2008，85，4： | 1 |
| 17 | Technology Development Analysis on Low Carbon for Power of Heavy-Duty Commercial Vehicle显示文摘Commercial vehicle industry worldwide is facing challenges from environmental pressures,stringent limits of CO_(2) emission,governmental regulations as well as ever-increased customer demands.This paper analyzes the above-mentioned challenges,especially in China,including the potential improvement to increase the brake thermal efficiency(BTE),with five levels of BTE proposed,ranging from current 45 to 60%in future,corresponding to China fuel consumption regulation(CFCR)in different phases.The authors also proposed the technology roadmaps to meet the upcoming CFCR3 and CFCR4;finally,the authors draw the conclusions to conform with ever-stringent regulation in China. | Jiangwei Liu Jun Li Yongjun Wang Dalu Dong Yansheng Yin Huayu Jin Shijie Sun Huili Dou Yanbo Shi Lei Fu Fei Ge | 2019 | Automotive Innovation2019，2，1： | 1 |
| 18 | Atomistic dynamics of disconnection-mediated grain boundary plasticity:A case study of gold nanocrystals显示文摘Grain boundary(GB)mediated deformation is a vital contributor to the plasticity of polycrystalline materials,where the disconnection model has become a widely recognized approach to depict the GB dynamics.However,experimental understanding of the atomistic disconnection dynamics remains scarce.In this case study of gold nanocrystals,atomistic disconnection dynamics governing the shear-coupled migration of flat GBs have been systematically investigated via in situ transmission electron microscopy nanomechanical testing supported by molecular dynamics simulations.Specifically,the site-dependent nucleation,shear-driven propagation,and diverse interactions associated with distinct GB disconnections are systematically elucidated and quantitatively compared.Moreover,the disconnection-mediated GB plasticity proves to prevail among different tilt and mixed GBs in gold.Eventually,a conceptual map of disconnection-mediated GB dynamics is established,which would furnish a unified understanding of GB plasticity in metallic materials. | Qi Zhu Haofei Zhou Yingbin Chen Guang Cao Chuang Deng Ze Zhang Jiangwei Wang | 2022 | Journal of Materials Science & Technology2022，，30： | 1 |
| 19 | Coordinated grain boundary deformation governed nanograin annihilation in shear cycling显示文摘Grain growth and shrinkage are essential to the thermal and mechanical stability of nanocrystalline metals,which are assumed to be governed by the coordinated deformation between neighboring grain boundaries(GBs)in the nanosized grains.However,the dynamics of such coordination has rarely been reported,especially in experiments.In this work,we systematically investigate the atomistic mechanism of coordinated GB deformation during grain shrinkage in an Au nanocrystal film through combined stateof-the-art in situ shear testing and atomistic simulations.We demonstrate that an embedded nanograin experiences shrinkage and eventually annihilation during a typical shear loading cycle.The continuous grain shrinkage is accommodated by the coordinated evolution of the surrounding GB network via dislocation-mediated migration,while the final grain annihilation proceeds through the sequential dislocation-annihilation-induced grain rotation and merging of opposite GBs.Both experiments and simulations show that stress distribution and GB structure play important roles in the coordinated deformation of different GBs and control the grain shrinkage/annihilation under shear loading.Our findings establish a mechanistic relation between coordinated GB deformation and grain shrinkage,which reveals a general deformation phenomenon in nanocrystalline metals and enriches our understanding on the atomistic origin of structural stability in nanocrystalline metals under mechanical loading. | Yingbin Chen Qishan Huang Qi Zhu Kexing Song Yanjun Zhou Haofei Zhou Jiangwei Wang | 2021 | Journal of Materials Science & Technology2021，，27： | 1 |
| 20 | Successive straw biochar application as a strategy to sequester carbon and improve fertility: A pot experiment with two rice/wheat rotations in paddy soil显示文摘 | Xu Zhao Jiangwei Wang Shenqiang Wang Guangxi Xing | 2014 | Plant and Soil (-)2014，，1： | 1 |
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