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| 1 | Abscisic Acid Signaling Inhibits Bmssinosteroid Signaling through Dampening the Dephosphorylation of BIN2 by ABI1 and ABI2显示文摘 | Haijiao Wang Jie Tang Jing Liu Jin Hu Jingjing Liu Yuxiao Chen Zhenying Cai Xuelu Wang | 2018 | Molecular Plant2018，11，2： | 17 |
| 2 | Nutritional assessment with different tools in leukemia patients after hematopoietic stem cell transplantation显示文摘Objective:Correct nutritional assessment is essential for leukemia patients after hematopoietic stem cell transplantation(HSCT).This study aimed to investigate the best nutritional assessment method for leukemia patients after HSCT,and find the possible nutritional risk of the patients during the transplantation process in order to intervene in the patients with nutritional risks and undernourished patients timely,so that the entire transplantation process could be successfully completed.Methods:A prospective study was performed in 108 leukemia patients after HSCT,and different nutritional assessment methods,including nutritional risk screening 2002(NRS2002),mini nutritional assessment(MNA),subjective globe assessment(SGA)and malnutritional universal screening tools(MUST),were used.The associations between nutritional status of these patients and nutritional assessment methods were analyzed.Results:A total of 108 patients completed SGA,and 99 patients completed NRS2002,MNA and MUST.During the treatment process,85.2%of the patients lost weight,wherein,50%lost weight greater than5%,and 42.6%had significantly reduced food intake.For nutritional risk assessment,the positive rates of NRS2002,MNA and MUST were 100%,74.7%and 63.6%,respectively.There was a significant difference(P<0.05)among the positive rates of NRS2002,MNA and MUST.In undernutrition assessment,the positive rate of SGA(83.3%)was significantly higher than that of MNA(17.2%)(P<0.05),and the incidence rate of nutritional risk among leukemia patients≤30 years old was greater than that of patients>30 years old(P<0.05).Conclusions:Patients with leukemia were in poor nutritional status during and after HSCT.The leukemia patients≤30 years old had a greater incidence rate of nutritional risk.As nutritional risk screening tool,the specificity of NRS2002 is not high,but it can be used for evaluating nutritional deficiencies.MNA is a good nutritional risk screening tool,but not an adequate tool for nutritional assessment.If assessment of undernutrition is necessary,the combination of all these screening tools and clinical laboratory indicators should be applied to improve accuracy. | Boshi Wang Xia Yan Jingjing Cai Yu Wang Peng Liu | 2013 | Chinese Journal of Cancer Research2013，25，6： | 14 |
| 3 | Time-domain analysis methodology for large-scale RLC circuits and its applications显示文摘With soaring work frequency and decreasing feature sizes, VLSI circuits with RLC parasitic components are more like analog circuits and should be carefully analyzed in physical design. However, the number of extracted RLC components is typically too large to be analyzed efficiently by using present analog circuit simulators like SPICE. In order to speedup the simulations without error penalty, this paper proposes a novel methodology to compress the time-descritized circuits resulted from numerical integration approximation at every time step. The main contribution of the methodology is the efficient structure-level compression of DC circuits containing many current sources, which is an important complement to present circuit analysis theory. The methodology consists of the following parts: 1) An approach is proposed to delete all intermediate nodes of RL branches. 2) An efficient approach is proposed to compress and back-solve parallel and serial branches so that it is error-free and of linear complexity to analyze circuits of tree topology. 3) The Y toπtransformation method is used to error-free reduce and back-solve the intermediate nodes of ladder circuits with the linear complexity. Thus, the whole simulation method is very accurate and of linear complexity to analyze circuits of chain topology. Based on the methodology, we propose several novel algorithms for efficiently solving RLC-model transient power/ground (P/G) networks. Among them, EQU-ADI algorithm of linear-complexity is proposed to solve RLC P/G networks with mesh-tree or mesh-chain topologies. Experimental results show that the proposed method is at least two orders of magnitude faster than SPICE while it can scale linearly in both time- and memory-complexity to solve very large P/G networks. | LUO Zuying CAI Yici Sheldon X.-D Tan HONG Xianlong WANG Xiaoyi PAN Zhu FU Jingjing | 2006 | Science in China(Series F)2006，49，5： | 13 |
| 4 | Comprehensive evaluation of nutritional status before and after hematopoietic stem cell transplantation in 170 patients with hematological diseases显示文摘Objective: To investigate the nutritional status of patients before and after hematopoietic stem cell transplantation(HSCT), and explore optimal methods for assessing nutritional status in patients with hematological diseases.Methods: This cohort study enrolled 170 patients who were diagnosed with hematological diseases and underwent allogeneic HSCT in the Department of Hematology, Peking University People's Hospital between May2011 and April 2013. We used fixed-point continuous sampling and four nutritional screening tools, Nutritional Risk Screening 2002(NRS-2002), Mini Nutritional Assessment(MNA), Subjective Global Assessment(SGA) and Malnutrition Universal Screening Tools(MUST), in combination with body measurements, to extensively screen and evaluate nutritional risks and status in patients receiving HSCT before entering and after leaving laminar air flow rooms.Results: After HSCT, patients had significant reduction in weight, hip circumference, waist-hip ratio, calf circumference, mid-upper arm circumference, and suprailiac skinfold thickness compared with pre-HSCT measurements. Before HSCT, NRS-2002 identified that 21.2% of patients were at nutritional risks, compared with100% after HSCT. MUST indicated that before HSCT, 11.77% of patients were at high nutritional risk,compared with 59.63% after HSCT. MNA assessed that 0.06% of patients were malnourished before HSCT,compared with 19.27% after HSCT. SGA identified that before HSCT, 1.76% of patients had mild to severe malnutrition, which increased to 83.3% after HSCT. There is a significant increase in the nutritional risk and malnutrition in patients who received HSCT.Conclusions: Before HSCT, some patients already had nutritional risk or nutritional deficiencies, and prompt and close nutritional screening or assessment should be performed. The nutritional status of patients after HSCT was generally deteriorated compared with that before transplantation. Body measurements should be taken more frequently during the subsequent treatment window in the laminar air flow rooms. After HSCT, it is recommended to combine MNA and SGA to fully evaluate the nutritional status, and thus provide timely and reasonable nutritional support. | Peng Liu Boshi Wang Xia Yan Jingjing Cai Yu Wang | 2016 | Chinese Journal of Cancer Research2016，28，6： | 9 |
| 5 | Effect of Gold Nanoparticles on the Photocatalytic and Photoelectrochemical Performance of Au Modified BiVO_4显示文摘An efficient visible light driven photocatalyst, gold nanoparticles(NPs) modified Bi VO_4(Au/Bi VO_4), has been synthesized by deposition-precipitation with urea method. Au/Bi VO_4 exhibits enhanced photocatalytic activity for phenol degradation underλ>400 nm irradiation but negligible activity underλ>535 nm,indicating that the surface plasmon resonance(SPR) effect is too weak for organic photodegradation. According to the photoelectrochemical results of the porous powder electrodes of Bi VO_4 and Au/Bi VO_4, the SPR effect of Au NPs has been assessed. The role of Au NPs as electron sinks or sources, which is controllable by incident photon energy and applied potentials, has been discussed. | Mingce Long Jingjing Jiang Yan Li Ruqiong Cao Liying Zhang Weimin Cai | 2011 | Nano-Micro Letters2011，3，3： | 8 |
| 6 | IL-17 sustains the plasma cell response via p38-mediated Bcl-xL RNA stability in lupus pathogenesis显示文摘Recent studies have demonstrated a central role for plasma cells in the development of autoimmune diseases,such as systemic lupus erythematosus(SLE).Currently,both the phenotypic features and functional regulation of autoreactive plasma cells during SLE pathogenesis remain largely unclear.In this study,we first found that a major subset of IL-17 receptor-expressing plasma cells potently produced anti-dsDNA IgG upon IL-17A(IL-17)stimulation in SLE patients and lupus mice.Using a humanized lupus mouse model,we showed that the transfer of Th17 cell-depleted PBMCs from lupus patients resulted in a significantly reduced plasma cell response and attenuated renal damage in recipient mice compared to the transfer of total SLE PBMCs.Moreover,long-term BrdU incorporation in lupus mice detected highly enriched long-lived BrdU+subsets among IL-17 receptor-expressing plasma cells.Lupus mice deficient in IL-17 or IL-17 receptor C(IL-17RC)exhibited a diminished plasma cell response and reduced autoantibody production with attenuated renal damage,while the adoptive transfer of Th17 cells triggered the plasma cell response and renal damage in IL-17-deficient lupus mice.In reconstituted chimeric mice,IL-17RC deficiency resulted in severely impaired plasma cell generation but showed no obvious effect on germinal center B cells.Further mechanistic studies revealed that IL-17 significantly promoted plasma cell survival via p38-mediated Bcl-xL transcript stabilization.Together,our findings identified a novel function of IL-17 in enhancing plasma cell survival for autoantibody production in lupus pathogenesis,which may provide new therapeutic strategies for the treatment of SLE. | Kongyang Ma Wenhan Du Fan Xiao Man Han Enyu Huang Na Peng Yuan Tang Chong Deng Lixiong Liu Yulan Chen Jingjing Li Shiwen Yuan Qin Huang Xiaoping Hong Dajun Hu Xiaoyan Cai Quan Jiang Dongzhou Liu Liwei Lu | 2021 | Cellular & Molecular Immunology2021，18，7： | 6 |
| 7 | Morphological Characteristics of Sand Waves in the Middle Taiwan Shoal Based on Multi-beam Data Analysis显示文摘A DTM map of the study area in the Taiwan Shoal was drawn based on precise and highdensity data acquired in a field survey by a multi-beam sounding system(R2Sonic2024). We identified sand waves in the study area at water depths of 13.89–49.12 m; the main sand waves had heights of 5–25 m, lengths of 0.1–2.0 km, and crest lines 0.1–6.5 km long. The spatial distribution of the sand waves on the seabed is dense in the north and sparse in the south and the directions range between 50°–80° and 90°–135°. Between the main sand waves, secondary sand waves develop with heights of 0.1–5.0 m and lengths of 10–100 m, which are difficult to detect by satellite remote sensing. By comparing the evolution structures of the secondary and main sand waves, we identified three evolution modes of the secondary sand waves: parallel, oblique, and divergent modes according to the relative crest directions. Suitable water depth, reciprocating current speeds between 40 and 100 cm/s, and abundant sediment supply create favorable conditions for the formation of linear sand waves. Comparing the DTM maps and profiles of the June 2012 and June 2013 surveys of the same area, we found that the shape and morphology of the sand waves remained mostly unchanged under normal hydrodynamic conditions. | BAO Jingjing CAI Feng REN Jianye ZHENG Yongling WU Chengqiang LU Huiquan XU Yan | 2014 | Acta Geologica Sinica(English Edition)2014，88，5： | 5 |
| 8 | Whole-genome resequencing of Osmanthus fragrans provides insights into flower color evolution显示文摘Osmanthus fragrans is a well-known ornamental plant that has been domesticated in China for 2500 years.More than 160 cultivars have been found during this long period of domestication,and they have subsequently been divided into four cultivar groups,including the Yingui,Jingui,Dangui,and Sijigui groups.These groups provide a set of materials to study genetic evolution and variability.Here,we constructed a reference genome of O.fragrans‘Liuyejingui’in the Jingui group and investigated its floral color traits and domestication history by resequencing a total of 122 samples,including 119 O.fragrans accessions and three other Osmanthus species,at an average sequencing depth of 15×.The population structure analysis showed that these 119 accessions formed an apparent regional cluster.The results of linkage disequilibrium(LD)decay analysis suggested that varieties with orange/red flower color in the Dangui group had undergone more artificial directional selection;these varieties had the highest LD values among the four groups,followed by the Sijigui,Jingui,and Yingui groups.Through a genome-wide association study,we further identified significant quantitative trait loci and genomic regions containing several genes,such as ethylene-responsive transcription factor 2 and Arabidopsis pseudoresponse regulator 2,that are positively associated with petal color.Moreover,we found a frameshift mutation with a 34-bp deletion in the first coding region of the carotenoid cleavage dioxygenase 4 gene.This frameshift mutation existed in at least one site on both alleles in all varieties of the Dangui group.The results from this study shed light on the genetic basis of domestication in woody plants,such as O.fragrans. | Hongguo Chen Xiangling Zeng Jie Yang Xuan Cai Yumin Shi Riru Zheng Zhenqi Wang Junyi Liu Xinxin Yi Siwei Xiao Qiang Fu Jingjing Zou Caiyun Wang | 2021 | Horticulture Research2021，8，1： | 5 |
| 9 | Abscisic acid and jasmonic acid are involved in drought priming-induced tolerance to drought in wheat显示文摘Drought stress is a limiting factor for wheat production and food security.Drought priming has been shown to increase drought tolerance in wheat.However,the underlying mechanisms are unknown.In the present study,the genes encoding the biosynthesis and metabolism of abscisic acid(ABA)and jasmonic acid(JA),as well as genes involved in the ABA and JA signaling pathways were up-regulated by drought priming.Endogenous concentrations of JA and ABA increased following drought priming.The interplay between JA and ABA in plant responses to drought priming was further investigated using inhibitors of ABA and JA biosynthesis.Application of fluridone(FLU)or nordihydroguaiaretic acid(NDGA)to primed plants resulted in lower chlorophyll-fluorescence parameters and activities of superoxide dismutase and glutathione reductase,and higher cell membrane damage,compared to primed plants(PD)under drought stress.NDGA+ABA,but not FLU+JA,restored priming-induced tolerance,as indicated by a finding of no significant difference from PD under drought stress.Under drought priming,NDGA induced the suppression of ABA accumulation,while FLU did not affect JA accumulation.These results were consistent with the expression of genes involved in the biosynthesis of ABA and JA.They suggest that ABA and JA are required for priming-induced drought tolerance in wheat,with JA acting upstream of ABA. | Xiao Wang Qing Li Jingjing Xie Mei Huang Jian Cai Qin Zhou Tingbo Dai Dong Jiang | 2021 | The Crop Journal2021，9，1： | 5 |
| 10 | Mould taper optimization for continuous casting steels by numerical simulation显示文摘A transient,two-dimensional,coupled finite element model was employed to simulate the solidification and shrinkage of continuous casting steels by means of ANSYSTM.In the model,a gap-dependent heat transfer condition was introduced to modify the heat flux function,and the variations of material thermal properties,mechanical properties as well as the yield function with temperature were considered.The solidification and shrinkage processes of four round billets and two square billets were simulated by indirect coupled method.Simulation results show that carbon content,pouring temperature,casting speed and shape of billets have distinct influence on the solidification shrinkage of billets.Ideal continuous parabolic tapers were designed and optimized according to the calculated shrinkage curves of billets. | Wang Tongmin Cai Shaowu Li Jun Xu Jingjing Chen Zongning Zhu Jing Cao Zhiqiang Li Tingju | 2010 | China Foundry2010，7，1： | 4 |
| 11 | Comparison of Clinical and Epidemiological Characteristics of Asymptomatic and Symptomatic SARS-CoV-2 Infection in Children显示文摘To understand the epidemiological and clinical features of the symptomatic and asymptomatic pediatric cases of COVID-19,we carried out a prospective study in Shanghai during the period of January 19 to April 30,2020.A total of 49 children(mean age 11.5±5.12 years)confirmed with SARS-CoV-2 infection were enrolled in the study,including 11(22.4%)domestic cases and 38(77.6%)imported cases.Nine(81.8%)local cases and 12(31.6%)imported cases had a definitive epidemiological exposure.Twenty-eight(57.1%)were symptomatic and 21(42.9%)were asymptomatic.Neither asymptomatic nor symptomatic cases progressed to severe diseases.The mean duration of viral shedding for SARS-CoV-2 in upper respiratory tract was 14.1±6.4 days in asymptomatic cases and 14.8±8.4 days in symptomatic cases(P>0.05).Forty-five(91.8%)cases had viral RNA detected in stool.The mean duration of viral shedding in stool was 28.1±13.3 days in asymptomatic cases and 30.8±18.6 days in symptomatic participants(P>0.05).Children<7 years shed viral RNA in stool for a longer duration than school-aged children(P<0.05).Forty-three(87.8%)cases had seropositivity for antibodies against SARS-CoV-2 within 1–3 weeks after confirmation with infection.In conclusion,asymptomatic SARS-CoV-2 infection may be common in children in the community during the COVID-19 pandemic wave.Asymptomatic cases shed viral RNA in a similar pattern as symptomatic cases do.It is of particular concern that asymptomatic individuals are potentially seed transmission of SARS-CoV-2 and pose a challenge to disease control. | Jiehao Cai Xiangshi Wang Jun Zhao Yanling Ge Jin Xu He Tian Hailing Chang Aimei Xia Jiali Wang Jinqiang Zhang Zhongqiu Wei Jingjing Li Chuning Wang Jianshe Wang Qirong Zhu Xiaowen Zhai Mei Zeng | 2020 | Virologica Sinica2020，35，6： | 4 |
| 12 | Short-Term and Continuing Stresses Differentially Interplay with Multiple Hormones to Regulate Plant Survival and Growth显示文摘压力植物激素, abscisic 酸(骆驼毛的织物) ,在便于植物熬过并且成长 undera 很好起重要作用压力条件的宽范围。主要集中于对短期的骆驼毛的织物处理的植物回答的以前的基因表示研究,而是持续骆驼毛的织物处理和他们的差别的效果糟糕被学习。这里,我们为 1h 或 9 d 与骆驼毛的织物对待植物,并且我们的染色体宽的分析显示差别在二个条件下面调整了基因是 tremendouslydifferent。我们分析了由把他们已知的应答的基因的整个集合用作集成他们的生合成的反馈规定的 reportersand 表明变化的另外的荷尔蒙。我们发现了那,在短期的骆驼毛的织物处理下面,表明 outputsof 支持生长的荷尔蒙, brassinosteroids 和赤霉素,和关於生命的压力应答的荷尔蒙, jasmonic 酸, weresignificantly 禁止了,当表明产量的植物生长素和乙烯被支持时。然而,支撑了骆驼毛的织物处理 repressedcytokinin 并且赤霉素发信号,但是刺激了植物生长素发信号。用荷尔蒙相关的异种的几个集合,我们包括受体或抄写管理者,在相应神经质的发信号小径的 foundcandidates 是到骆驼毛的织物的必要 inresponding。我们的调查结果显示骆驼毛的织物依赖者的相互作用在植物在不同层次 areinvolved 与荷尔蒙强调信号在短暂应力下面幸存并且适应继续紧张的 environments.Key 词: | Cangjing Yang Jingjing Liu Xinran Dong Zhenying Cai Weidong Tian Xuelu Wang | 2014 | Molecular Plant2014，7，5： | 4 |
| 13 | Cancer classification based on microarray gene expression data using a principal component accumulation method显示文摘The classification of cancer is a major research topic in bioinformatics. The nature of high dimensionality and small size associated with gene expression data,however,makes the classification quite challenging. Although principal component analysis (PCA) is of particular interest for the high-dimensional data,it may overemphasize some aspects and ignore some other important information contained in the richly complex data,because it displays only the difference in the first twoor three-dimensional PC subspaces. Based on PCA,a principal component accumulation (PCAcc) method was proposed. It employs the information contained in multiple PC subspaces and improves the class separability of cancers. The effectiveness of the present method was evaluated by four commonly used gene expression datasets,and the results show that the method performs well for cancer classification. | LIU JingJing CAI WenSheng SHAO XueGuang | 2011 | Science China Chemistry2011，54，5： | 2 |
| 14 | Polycrystalline diamond MESFETs by Au-mask technology for RF applications显示文摘Metal-semiconductor field effect transistors (MESFETs) were fabricated on H-terminated polycrystalline diamond.The DC characteristics of the p-channel MESFET showed a maximum drain current density of 204 mA/mm at a gate-source voltage of 6 V,and a maximum transconductance of 20 mS/mm at a gate-source voltage of 1.5 V.The small signal S-parameters of MESFET with 2 100 m gate width and 2 m gate length were measured.An extrinsic cut-off frequency (fT) of 1.7 GHz and the maximum oscillation frequency (fmax) of 2.5 GHz were obtained,which was the first report on diamond MESFETs with RF characteristics in China. | FENG ZhiHong WANG JingJing HE ZeZhao DUN ShaoBo YU Cui LIU JinLong ZHANG PingWei GUO Hui LI ChengMing CAI ShuJun | 2013 | Science China(Technological Sciences)2013，56，4： | 2 |
| 15 | Differential Privacy Preserving Dynamic Data Release Scheme Based on Jensen-Shannon Divergence显示文摘Health monitoring data or the data about infectious diseases such as COVID-19 may need to be constantly updated and dynamically released,but they may contain user's sensitive information.Thus,how to preserve the user's privacy before their release is critically important yet challenging.Differential Privacy(DP)is well-known to provide effective privacy protection,and thus the dynamic DP preserving data release was designed to publish a histogram to meet DP guarantee.Unfortunately,this scheme may result in high cumulative errors and lower the data availability.To address this problem,in this paper,we apply Jensen-Shannon(JS)divergence to design the OPTICS(Ordering Points To Identify The Clustering Structure)scheme.It uses JS divergence to measure the difference between the updated data set at the current release time and private data set at the previous release time.By comparing the difference with a threshold,only when the difference is greater than the threshold,can we apply OPTICS to publish DP protected data sets.Our experimental results show that the absolute errors and average relative errors are significantly lower than those existing works. | Ying Cai Yu Zhang Jingjing Qu Wenjin Li | 2022 | China Communications2022，19，6： | 2 |
| 16 | An improved method validation for rapid determination of acrylamide in foods by ultra-performance liquid chromatography combined with tandem mass spectrometry 显示文摘 | Zhang Yu Jiao Jingjing Cai Zengxuan | 2007 | Journal of Chromatography A2007，1142，： | 1 |
| 17 | Effect of TiO_2 nanoparticle aggregation on marine microalgae Isochrysis galbana显示文摘TiO_2 nanoparticles(NPs) could adversely impact aquatic ecosystems. However, the aggregation of these NPs could attenuate this effect. In this work, the biological effects of TiO_2 NPs on a marine microalgae Isochrysis galbana were investigated. The aggregation kinetics of TiO_2 NPs under different conditions was also investigated to determine and understand these effects. Results showed that, though TiO_2 NPs had no obvious impact on the size and reproducibility of algal cells under testing conditions, they caused a negative effect on algal chlorophyll, which led to a reduction in photosynthesis. Furthermore, fast aggregation of TiO_2 NPs occurred under all conditions, especially at the pH close to the p Hzpc. Increasing ionic strength and NP concentration also enhanced the aggregation rate.The aggregation and the following sedimentation of TiO_2 NPs reduced their adverse effects on I. galbana. | Ji Hu Jianmin Wang Shuxia Liu Zhechao Zhang Haifeng Zhang Xiaoxia Cai Jianming Pan Jingjing Liu | 2018 | Journal of Environmental Sciences2018，30，4： | 1 |
| 18 | Quantitative Measurements of the Ciliary Body in Eyes with Malignant Glaucoma after Trabeculectomy Using Ultrasound Biomicroscopy显示文摘 | Zhonghao Wang Jingjing Huang Jialiu Lin Xuanwei Liang Xiaoyu Cai Jian Ge | 2013 | Ophthalmology2013，，： | 1 |
| 19 | An improved method validation for rapid determination of acrylamide in foods by ultra- performance liquid chromatography combined with tandem mass spectrometry显示文摘 | Yu Zhang Jingjing Jiao Zengxuan Cai | 2007 | Journal of chromatography A2007，1142，2： | 1 |
| 20 | Association Between Lipid Profiles and Left Ventricular Hypertrophy:New Evidence from a Retrospective Study显示文摘Objective To explore the association between lipid profiles and left ventricular hypertrophy in a Chinese general population.Methods We conducted a retrospective observational study to investigate the relationship between lipid markers[including triglycerides,total cholesterol,low-density lipoprotein cholesterol,high-density lipoprotein(HDL)cholesterol,non-HDL-cholesterol,apolipoprotein A-I,apolipoprotein B,lipoprotein[a],and composite lipid profiles]and left ventricular hypertrophy.A total of 309,400 participants of two populations(one from Beijing and another from nationwide)who underwent physical examinations at different health management centers between 2009 and 2018 in China were included in the cross-sectional study.7,475 participants who had multiple physical examinations and initially did not have left ventricular hypertrophy constituted a longitudinal cohort to analyze the association between lipid markers and the new-onset of left ventricular hypertrophy.Left ventricular hypertrophy was measured by echocardiography and defined as an end-diastolic thickness of the mterventricular septum or left ventricle posterior wall>11 mm.The Logistic regression model was used in the cross-sectional study.Cox model and Cox model with restricted cubic splines were used in the longitudinal cohort.Results In the cross-sectional study for participants in the highest tertile of each lipid marker compared to the respective lowest,triglycerides[odds ratio(OR):1.2S0,95%CI:1.060 to 1.474],HDL-cholesterol(OR:0.780,95%CI:0.662 to 0.918),and lipoprotein(a)(OR:1.311,95%C7:1.115 to 1.541)had an association with left ventricular hypertrophy.In the longitudinal cohort,for participants in the highest tertile of each lipid marker at the baseline compared to the respective lowest,triglycerides[hazard ratio(HR):3.277,95%C/:1.720 to 6.244],HDL-cholesterol(HR:0.516,95%C7:0.283 to 0.940),non-HDL-cholesterol(HR:2.309,95%C/:1.296 to 4.112),apolipoprotein B(HR:2.244,95%CI:1.251 to 4.032)showed an association with new-onset left ventricular hypertrophy.In the Cox model with forward stepwise selection,triglycerides were the only lipid markers entered into the final model.Conclusion Lipids levels,especially triglycerides,are associated with left ventricular hypertrophy.Controlling triglycerides level potentiate to be a strategy in harnessing cardiac remodeling but deserve to be furdier investigated. | Xuewei Huang Keqiong Deng Juanjuan Qin Fang Lei Xingyuan Zhang Wenxin Wang Lijin Lin Yuming Zheng Dongai Yao Huiming Lu Feng Liu Lidong Chen Guilan Zhang Yueping Liu Qiongyu Yang Jingjing Cai Zhigang She Hongliang Li | 2022 | Chinese Medical Sciences Journal2022，37，2： | 1 |
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