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| 1 | Characterization of spontaneous otoacoustic emissions in 2–4 day old neonates with respect to gender and ear显示文摘BACKGROUND: Spontaneous otoacoustic emissions (SOAEs) are regarded as a valuable audio- metric parameter that objectively reflects the function of outer hair cells (OHCs). Many studies have reported that the incidence of SOAEs in adults is less than 50%. Therefore, measurement of SOAEs may be of little value to clinical examinations. However, the incidence of SOAEs in infants and neonates is higher than in adults. OBJECTIVE: To analyze the basic characteristics of SOAEs in 2–4 day old neonates, and to dem- onstrate the difference in OHC function between sexes and ears. DESIGN, TIME AND SETTING: Neurophysiological contrast study, performed in the Department of Neonates, Beijing Chaoyang Hospital, Capital Medical University, between December 2007 and August 2008. PARTICIPANTS: A total of 112 newborns (224 ears) consisting of 59 females and 53 males were included in this study. METHODS: The probe was adapted and embedded in the neonate external auditory canal with a foam rubber earplug after checking and clearing up the outer ear canal. The presence of SOAEs was determined when the signal amplitude had a clear peak exceeding –30 dB, or was 3 dB above the noise floor. MAIN OUTCOME MEASURES: The incidence of SOAEs, the number of SOAE signal peaks, and the maximal tension of SOAEs. RESULTS: The incidence in females (79.7%) was higher than males (76.4%) (P > 0.05), and the incidence in right ears (86.6%) was higher than in left ears (69.6%) (P < 0.05). There were no sig- nificant difference in the number of SOAE peaks between females and males (4.49 vs. 4.28), or between right ears and left ears (4.62 vs. 4.12) (P > 0.05). The mean maximum SOAE level per ear in females (–3.29 ± 9.28) dB sound pressure level (SPL) was slightly higher than that in males (–3.91 ± 9.14) dB SPL (P > 0.05). Also, the mean maximum SOAE level in right ears (–2.03 ± 9.11) dB SPL was higher than in left ears (–5.50 ± 9.65) dB SPL (P < 0.05). The maximum SOAE level showed a positive correlation with maximum SOAE number in emitting ears (r = 0.55, P < 0.01). CONCLUSION: The incidence of SOAEs in neonates is high (78.1%) within 4 days of birth. The in-cidence of SOAEs and the maximum SOAE level exhibited a significant difference between right and left ears, but the difference between sexes was insignificant. Both the strongest SOAE signal peak and number of SOAEs per ear are representative of the function OHCs. | Jinfeng Liu Baoyu Shi Ningyu Wang Jinlan Li | 2009 | Neural Regeneration Research2009,4,1: | 8 |
| 2 | Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2显示文摘Host cellular receptors play key roles in the determination of virus tropism and pathogenesis.However,little is known about SARS-CoV-2 host receptors with the exception of ACE2.Furthermore,ACE2 alone cannot explain the multi-organ tropism of SARS-CoV-2 nor the clinical differences between SARS-CoV-2 and SARS-CoV,suggesting the involvement of other receptor(s).Here,we performed genomic receptor profiling to screen 5054 human membrane proteins individually for interaction with the SARS-CoV-2 capsid spike(S)protein.Twelve proteins,including ACE2,ASGR1,and KREMEN1,were identified with diverse S-binding affinities and patterns.ASGR1 or KREMEN1 is sufficient for the entry of SARS-CoV-2 but not SARS-CoV in vitro and in vivo.SARS-CoV-2 utilizes distinct ACE2/ASGR1/KREMEN1(ASK)receptor combinations to enter different cell types,and the expression of ASK together displays a markedly stronger correlation with virus susceptibility than that of any individual receptor at both the cell and tissue levels.The cocktail of ASK-related neutralizing antibodies provides the most substantial blockage of SARS-CoV-2 infection in human lung organoids when compared to individual antibodies.Our study revealed an interacting host receptome of SARS-CoV-2,and identified ASGR1 and KREMEN1 as alternative functional receptors that play essential roles in ACE2-independent virus entry,providing insight into SARS-CoV-2 tropism and pathogenesis,as well as a community resource and potential therapeutic strategies for further COVID-19 investigations. | Yunqing Gu Jun Cao Xinyu Zhang Hai Gao Yuyan Wang Jia Wang Juan He Xiaoyi Jiang Jinlan Zhang Guanghui Shen Jie Yang Xichen Zheng Gaowei Hu Yuanfei Zhu Shujuan Du Yunkai Zhu Rong Zhang Jianqing Xu Fei Lan Di Qu Guoliang Xu Yun Zhao Dong Gao Youhua Xie Min Luo Zhigang Lu | 2022 | Cell Research2022,32,1: | 8 |
| 3 | Insight into the catalytic activity of MXenes for hydrogen evolution reaction显示文摘MXenes have exhibited great potential as cost-effective electrocatalysts for hydrogen evolution reaction(HER). However, insight into the origin of activity is still missing. Herein, on the basis of a systematical investigation of the HER performance of 20 MXenes(M_2NO_2 and M_2CO_2, M = Sc, Ti, V, Cr, Zr, Nb, Mo,Hf, Ta and W), a Fermi-abundance model is proposed to understand variation of the activity in different MXenes. It is found that the occupied p electronic states of surface O atoms play a decisive role in the HER activity of MXenes. More importantly, Ti_2NO_2 and Nb_2NO_2 are found to be promising HER electrocatalysts with the free energy for hydrogen adsorption close to zero. This work not only provides possible catalysts for HER, the developed Fermi-abundance model but also is applicable to other two-dimensional materials and may serve as a simple descriptor of the intrinsic HER activity. | Xiaowan Bai Chongyi Ling Li Shi Yixin Ouyang Qiang Li Jinlan Wang | 2018 | Science Bulletin2018,63,21: | 6 |
| 4 | HPLC–MS and HPLC–MS/MS analysis of seven active constituents of Xiao-Xu-Ming decoction and application to a pharmacokinetic study after oral administration to rat显示文摘Xiao-xu-ming decoction(XXMD)is a traditional Chinese medicine that has been widely used to treat theoplegia and its sequelae.This paper reports the development of three separate assays based on reversed phase high-performance liquid chromatography–mass spectrometry(HPLC–MS)and HPLC–MS/MS for the determination of seven active constituents of XXMD viz oroxylin A-7-O-glucuronide,wogonoside,liquiritigenin,cimifugin,5-O-methylvisammiol,glycyrrhizic acid and glycyrrhetinic acid in rat plasma.All calibration curves were linear(r >0.99)with lower limits of quantitation(LLOQs)<12.4 ng/mL.Intra-and inter-day precisions(as relative standard deviation)were all <10.7% with recoveries in the range of 88.7–113%.In addition,the seven analytes were shown to be stable in rat plasma samples under relevant storage conditions.The validated methods were successfully applied to a pharmacokinetic study in rat after oral administration of XXMD. | Yilin Wang Chunguang Ding Caisheng Wu Kehe Du Jinlan Zhangn Hailin Qin Jinfeng Hou Guanhua Du | 2012 | Acta Pharmaceutica Sinica B2012,2,2: | 6 |
| 5 | Magnetic two-dimensional layered crystals meet with ferromagnetic semiconductors显示文摘The existence of intrinsic ferromagnetic semiconductors(FMSs)in twodimensional(2D)materials has been a long-term concern and pursuit.Recent breakthroughs in the 2D FMSs,such as CrGeTe3 and CrX3(X=Cl,Br,I)from bulk down to monolayer,have stimulated intensive researches on new physical phenomena and creative concepts.This minireview mainly summarizes recent progress of 2D intrinsic FMSs in theoretical side,and focuses on the ongoing strategies proposed to enhance ferromagnetism,involving the mechanisms of magnetic exchange interaction and the significance of magnetic anisotropy.Meanwhile,spin-related multifunctionality with ultrathin FMSs and their van de Waals heterostructures in magnetoelectric,valleytronic,and nondissipative electronic technology are introduced,as well as the current challenges and the prospects in this field are discussed. | Yilv Guo Bing Wang Xiwen Zhang Shijun Yuan Liang Ma Jinlan Wang | 2020 | InfoMat2020,2,4: | 6 |
| 6 | Discovery of the Dagele Eclogite in East Kunlun,Western China and Its Zircon SHRIMP U-Pb Ages:New Constrains on the Central Kunlun Suture Zone显示文摘Objective Eclogites are important indicators of ancient plate boundaries or paleosuture zones.Despite their great geological significance,very few investigations have been carried out in the Kunlun region.The Central East Kunlun fault zone was believed to be an Early Paleozoic suture zone,but there has been no reliable evidence for this,though studies on ophiolite,granite,and basic granulite indicate that the Early Paleozoic orogeny occurred in the East Kunlun.This work focused on the Dagele eclogites | DU Wei JIANG Changyi Tang Zhongli XIA Mingzhe XIA Zhaode LING Jinlan ZHOU Wei WANG Bangyao | 2017 | Acta Geologica Sinica(English Edition)2017,91,3: | 5 |
| 7 | Rheological Properties of Hydrophobically Associating Polyacrylamide Solution显示文摘A temperature-resistant, salt-tolerant polyacrylamide, hydrophobically associating polymer (HAP), was synthesized in the State Key Laboratory of Heavy Oil Processing. The rheological behavior of HAP solution was investigated by means of flow experiments in porous media and by using a HAAKE RS600 rheometer. The results of Nuclepore membrane filtration showed that filtration time increased sharply when the critical association concentration was reached. Shear rate had a greater impact on viscosity and shear stress with increasing HAP concentration. The HAP solution with a concentration of 100 mg/L (salinity 32,868 mg/L) exhibited negative thixotropy. However, at the same salinity the HAP solution showed thixotropy and its viscosity became greater when the polymer concentration increased to 1,500 mg/L. The flow experiments in cemented core samples indicated that the resistance factor and residual resistance factor of the HAP solution were 31.8 and 12 when polymer concentration and salinity were 1,500 mg/L, 32,868 mg/L at 85℃ respectively, which is favorable for flooding application. Such factors of partially hydrolyzed polyacrylamide 3530S were merely 3.14 and 1.71, so it could not be applied to polymer flooding in the oilfield with high temperature and high salinity. | Ren Kun Wang Jinlan Lin Meiqin Xu Chunming | 2006 | Petroleum Science2006,3,2: | 5 |
| 8 | Bimetallic Nickel Cobalt Sulfide as E cient Electrocatalyst for Zn–Air Battery and Water Splitting显示文摘The development of e cient earth-abundant electrocatalysts for oxygen reduction, oxygen evolution, and hydrogen evolution reactions(ORR, OER, and HER) is important for future energy conversion and energy storage devices, for which both rechargeable Zn–air batteries and water splitting have raised great expectations. Herein, we report a single-phase bimetallic nickel cobalt sulfide((Ni,Co)S_2) as an e cient electrocatalyst for both OER and ORR. Owing to the synergistic combination of Ni and Co, the(Ni,Co)S_2 exhibits superior electrocatalytic performance for ORR, OER, and HER in an alkaline electrolyte, and the first principle calculation results indicate that the reaction of an adsorbed O atom with a H_2O molecule to form a *OOH is the potential limiting step in the OER. Importantly, it could be utilized as an advanced air electrode material in Zn–air batteries, which shows an enhanced charge–discharge performance(charging voltage of 1.71 V and discharge voltage of 1.26 V at 2 mA cm^(-2)), large specific capacity(842 mAh g_(Zn)^(-1) at 5 mA cm^(-2)), and excellent cycling stability(480 h). Interestingly, the(Ni,Co)S_2-based Zn–air battery can e ciently power an electrochemical water-splitting unit with(Ni,Co)S_2 serving as both the electrodes. This reveals that the prepared(Ni,Co)S_2 has promising applications in future energy conversion and energy storage devices. | Jingyan Zhang Xiaowan Bai Tongtong Wang Wen Xiao Pinxian Xi Jinlan Wang Daqiang Gao John Wang | 2019 | Nano-Micro Letters2019,11,1: | 4 |
| 9 | Bortezomib improves progression-free survival in multiple myeloma patients overexpressing preferentially expressed antigen of melanoma显示文摘 | Qin Yazhen Lu Jin Bao Li Zhu Honghu Li Jinlan Li Lingdi Lai Yueyun Shi Hongxia Wang Yazhe Liu Yanrong Jiang Bin Huang Xiaojun | 2014 | Chinese Medical Journal2014,,9: | 4 |
| 10 | Biostratigraphical significance of the Devonian Sinoleperditiini(Ostracoda)显示文摘The Tribe Sinoleperditiini (Ostracoda), which is mainly distributed in South China and its adjacent areas, is a single natural group of the Leperditiidae, characterized by the development of a trailing chevron muscle scar. This tribe is known only from the Devonian and ranges through most of the Devonian. The evolutionary trends within the Sinoleperditiini have been well documented and are exemplified by changes in the trailing chevron muscle scar. The main evolutionary change is a tendency of the trailing chevron muscle scar to extend ventrally through time, as demonstrated by the increasing ratio (th/ah) of the vertical height of the trailing chevron muscle scar (th) to that of the adductor muscle scar (ah). The recent discovery of a sinoleperditiine assemblage (th/ah values available) in the middle-upper Lower Emsian Shanglun Formation allows to propose a sinoleperditiine biostratigraphical sequence for the Devonian. This sequence contains 11 assemblages (th/ah value available for each assemblage), which cover all the 7 Devonian stages and some substages. This sequence is particularly useful for correlating and dating Devonian rocks in the littoral clastic, lagoonal and restricted or semirestricted car-bonate platform facies where these ostracodes are most abundant and other fossils are un-common. | WANG Shangqi PENG Jinlan | 2005 | Science China Earth Sciences2005,48,10: | 3 |
| 11 | Excitation-emission matrix (EEM) fluorescence spectroscopy for characterization of organic matter in membrane bioreactors: Principles, methods and applications显示文摘The membrane bioreactor(MBR)technology is a rising star for wastewater treatment.The pollutant elimination and membrane fouling performances of MBRs are essentially related to the dissolved organic matter(DOM)in the system.Three-dimensional excitation-emission matrix(3D-EEM)fluorescence spectroscopy,a powerful tool for the rapid and sensitive characterization of DOM,has been extensively applied in MBR studies;however,only a limited portion of the EEM fingerprinting information was utilized.This paper revisits the principles and methods of fluorescence EEM,and reviews the recent progress in applying EEM to characterize DOM in MBR studies.We systematically introduced the information extracted from EEM by considering the fluorescence peak location/intensity,wavelength regional distribution,and spectral deconvolution(giving fluorescent component loadings/scores),and discussed how to use the information to interpret the chemical compositions,physiochemical properties,biological activities,membrane retention/fouling behaviors,and migration/transformation fates of DOM in MBR systems.In addition to conventional EEM indicators,novel fluorescent parameters are summarized for potential use,including quantum yield,Stokes shift,excited energy state,and fluorescence lifetime.The current limitations of EEM-based DOM characterization are also discussed,with possible measures proposed to improve applications in MBR monitoring. | Jinlan Yu Kang Xiao Wenchao Xue Yue-xiao Shen Jihua Tan Shuai Liang Yanfen Wang Xia Huang | 2020 | Frontiers of Environmental Science & Engineering2020,14,2: | 3 |
| 12 | A Unified Approach to Construct Generalized B-Splines for Isogeometric Applications显示文摘Generalized B-splines have been employed as geometric modeling and numerical simulation tools for isogeometric analysis(IGA for short). However, the previous models used in IGA,such as trigonometric generalized B-splines or hyperbolic generalized B-splines, are not the unified mathematical representation of conics and polynomial parametric curves/surfaces. In this paper,a unified approach to construct the generalized non-uniform B-splines over the space spanned by{α(t), β(t), ξ(t), η(t), 1, t, ···, t^(n-4)} is proposed, and the corresponding isogeometric analysis framework for PDE solving is also studied. Compared with the NURBS-IGA method, the proposed frameworks have several advantages such as high accuracy, easy-to-compute derivatives and integrals due to the non-rational form. Furthermore, with the proposed spline models, isogeometric analysis can be performed on the computational domain bounded by transcendental curves/surfaces, such as the involute of circle, the helix/helicoid, the catenary/catenoid and the cycloid. Several numerical examples for isogeometric heat conduction problems are presented to show the effectiveness of the proposed methods. | XU Gang SUN Ningning XU Jinlan HUI Kin-Chuen WANG Guozhao | 2017 | Journal of Systems Science & Complexity2017,30,4: | 3 |
| 13 | Crystal phase-controlled growth of PtCu and PtCo alloys on 4H Au nanoribbons for electrocatalytic ethanol oxidation reaction显示文摘Crystal phase can greatly affect the physicochemical properties and applications of nanomaterials.However,it stil remains a great challenge to synthesize nanostructures with the same composition and morphology but different phases in order to explore the phase-dependent properties and applications.Herein,we report the crystal phase-controlled synthesis of PtCu alloy shells on 4H Au nanoribbons(NRBs),referred to as 4H-Au NRBs,to form the 4H-Au@PtCu core-shell NRBs.By tuning the thickness of PtCu,4H-PtCu and face-centered cubic(cc)phase PICu(cc-PtCu)alloy shells are successtully grown on the 4H-Au NRB cores.This thickness-dependent phase-controlled growth strategy can also be used to grow PtCo alloys with 4H or fcc phase on 4H-Au NRBs.Significantly,when used as electrocatalysts for the ethanol oxidation reaction(EOR)in alkaline media,the 4H-Au@4H-PtCu NRBs show much better EOR performance than the 4H-Au@fcc-PtCu NRBs,and both of them possess superior performance compared to the commercial Pt black.Our study provides a strategy on phase-contolled synthesis of nanomaterials used for crystal phase-dependent applications. | Jie Wang Jian Zhang Guigao Liu Chongyi Ling Bo Chen Jingtao Huang Xiaozhi Liu Bing Li An-Liang Wang Zhaoning Hu Ming Zhou Ye Chen Hongfei Cheng Jiawei Liu Zhanxi Fan Nailiang Yang Chaoliang Tan Lin Gu Jinlan Wang Hua Zhang | 2020 | Nano Research2020,13,7: | 2 |
| 14 | A k-Coverage Scheduling Scheme in Wireless Sensor Network Based on Hard-Core Process in Rayleigh Fading Channel显示文摘Sensing coverage is a fundamental design issue in wireless sensor networks(WSNs),while sensor scheduling ensures coverage degree to the monitored event and extends the network lifetime.In this paper,we address k-coverage scheduling problem in dense WSNs,we maintain a connected k-coverage energy efficiently through a novel Hard-Core based Coordinated Scheduling(HCCS),in which hardcore is a thinning process in stochastic geometry that inhibits more than one active sensor covering any area redundantly in a minimum distance. As compared with existing coordinated scheduling,HCCS allows coordination between sensors with little communication overhead.Moreover,due to the traditional sensing models in k-coverage analysis is unsuitable to describe the characteristic of transmit channel in dense WSNs,we propose a novel sensing model integrating Rayleigh Fading and Distribution of Active sensors(RFDA),and derive the coverage measure and k-coverage probability for the monitored event under RFDA. In addition,we analyze the influence factors,i.e. the transmit condition and monitoring degree to the k-coverage probability. Finally,through Monte Carlo simulations,it is shown that the k-coverage probability of HCCS outperforms that of its random scheduling counterpart. | KANG Lin LI Xiuhua ZHANG Yinghai WANG Weidong LI Jinlan | 2015 | China Communications2015,12,11: | 2 |
| 15 | Development of Specific SSR Molecular Marker of 'Huangzhou Radish' Based on Purity Identification显示文摘As an excellent local crop variety of Huanggang,'Huangzhou radish' has been widely promoted and its market influence is increasing day by day.Recently,the purity of 'Huangzhou radish' has declined deeply,so it is urgent to improve and strengthen the purity and viability of 'Huangzhou radish' including bad phenomena such as degeneration of varieties after self-pollination.At present,there was no SSR molecular marker can be used for genetic diversity identification of 'Huangzhou radish'.SSR molecular marker can provide a favorable tool to study 'Huangzhou radish'.In this study,'Xiakang','Hongbao'and 'Huangzhou radish' were used as experimental materials,100 SSR primers were screened,and 25 pairs of SSR primers were selected.Finally,two pairs of primers were selected for identification of the purity of 'Huangzhou radish' by non-denatured polyacrylamide gel electrophoresis (PAGE).The results showed that R-102 and R-112 primer pairs could amplify the special bands for 'Huangzhou radish' from above three kinds of radishes.These two pairs of primers could be developed as SSR markers to identify the specificity and purity of 'Huangzhou radish'.Furthermore,this study provides convenient conditions for promoting the economic and social value of 'Huangzhou radish'. | Pingan WANG Jinlan YAO Qiuyu ZENGCHEN Linling WANG Jingcai LI Yuanping FANG Shisheng LI | 2019 | Agricultural Biotechnology2019,8,5: | 2 |
| 16 | Direct ink writing of programmable functional silicone-based composites for 4D printing applications显示文摘Polydimethylsiloxane(PDMS)has been widely used in flexible electronics,soft robotics,and bioelectronics.However,the fabrication of PDMS-based devices has mostly relied on conventional approaches,such as casting and molding,thereby limiting their potential.Here we fabricate PDMS-based composites with programmable microstructures by direct ink writing and realize their practical functionalities of four-dimensional(4D)printing.The mechanical,thermomechanical and magnetic properties of the three-dimensional-printed composites can be well tailored by using carbon,metal,or ceramic functional fillers.By taking advantage of the printable,flexible,and magnetic PDMS composites,we demonstrate new practical functionalities of 4D printing by designing programmable architectures,including magnetic-field-driven battery cases and patchworks,as well as arbitrary morphing ceramic structures.In particular,4D-printed batteries are constructed by PDMS-based battery cases for the first time,which can be actuated via external magnetic field.This study broadens the paradigm of 4D printing for prospective applications,such as implant batteries,biomimetic engineering,and customized biomedical devices. | Zhiyang Lyu J.ustin Koh Gwendolyn J.H.Lim Danwei Zhang Ting Xiong Lei Zhang Siqi Liu Junfei Duan Jun Ding John Wang Jinlan Wang Yunfei Chen Chaobin He | 2022 | Interdisciplinary Materials2022,1,4: | 2 |
| 17 | Transcript Profiling Reveals Abscisic Acid,Salicylic Acid and Jasmonic-Isoleucine Pathways Involved in High Regenerative Capacities of Immature Embryos Compared with Mature Seeds in japonica Rice显示文摘Induced pluripotent cell mass plays a role in genetic transformation mediated by Agrobacterium. Mature seeds are more recalcitrant to the induction of suitable calli than immature embryos in rice, but the exact molecular mechanisms involved remain elusive. In this study, the morphological structure of calli induced from mature seeds and immature embryos were observed under a scanning electron microscope using a paraffin embedded technique. Meanwhile, a total of 2 173 upand down-regulated genes were identified in calli induced from mature seeds and immature embryos by RNA-seq technique and furtherly confirmed by quantitative real-time PCR. The results revealed the remarkable morphological differences in calli induced from mature seeds and immature embryos, and plant hormone signal transduction and hormone biosynthesis pathways, such as abscisic acid, salicylic acid and jasmonic-isoleucine, were found to play roles in somatic embryogenesis. This study provided comprehensive gene expression sets for mature seeds and immature embryos that were served as an important platform resource for further functional studies in plant embryogenesis. | XIAO Kaizhuan MAO Xiaohui WANG Yingheng WANG Jinlan WEI Yidong CAI Qiuhua XIE Hua'an ZHANG Jianfu | 2018 | Rice science2018,25,4: | 1 |
| 18 | Melting behavior in ultrathin metallic nanowires显示文摘 | Wang Jinlan Chen Xiaoshuang Wang Guanghou | 2002 | Physical Review B2002,66,08: | 1 |
| 19 | The Research and Application of the Strategic Analysisand Selection of R&D Project | LIN Sheng LIU Jinlan GU Yao YANG Lei WANG Chu(Tianjin University, Tianjin 300072 P.R.Cbina) | 1998 | Systems Science and Systems Engineering1998,8,4: | 1 |
| 20 | Applications of F-expansion Method to Class of Nonlinear Klein-Gordon Equation显示文摘 | LI BAOAN CHEN JINLAN WANG MINGLING | 2005 | J of Henan Univ of Sci & Technol(natural science)2005,26,5: | 1 |