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| 1 | Lead phytotoxicity in soils and nutrient solutions is related to lead induced phosphorus deficiency显示文摘 | Karlien Cheyns Sofie Peeters Dorien Delcourt Erik Smolders | 2012 | Environmental Pollution2012，，： | 1 |
| 2 | Avoidance of system- ic anticoagulation during intermittent haemodialysis with heparin-grafted polyacrilonitrile membrane and ci- trate-enriched dialysate: a retrospective cohort study 显示文摘 | Karlien F Karl Rita J | 2014 | BMC Nephrology2014，15，3： | 1 |
| 3 | Estimation of the glomerular filtration rate in children: which algorithm should be used?显示文摘 | Lyonne K. Rossum Ron A. A. Mathot Karlien Cransberg Robert Zietse Arnold G. Vulto | 2005 | Pediatric Nephrology2005，，12： | 1 |
| 4 | Long‐term follow‐up of sacral neuromodulation for lower urinary tract dysfunction显示文摘 | Karlien Peeters Arun Sahai Dirk De Ridder Frank Van Der Aa | 2014 | BJU Int2014，，： | 1 |
| 5 | Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice显示文摘 | Fu Jianxin Gerhardt Holger McDaniel J Michael Xia Baoyun Liu Xiaowei Ivanciu Lacramioara Ny Annelii Hermans Karlien Silasi-Mansat Robert McGee Samuel Nye Emma Ju Tongzhong Ramirez Maria I Carmeliet Peter Cummings Richard D Lupu Florea Xia | 2008 | Journal of Clinical Investigation2008，，11： | 1 |
| 6 | On some inadmissibility results for the scale parameters of selected gamma populations显示文摘 | NEERAJ MISRAA EDWARD C VAN DER MEULENB KARLIEN VANDEN BRANDENB | 2006 | Journal of Statistical Planning and Inference2006，136，： | 1 |
| 7 | Effects of Discontinuing Anti–Tumor Necrosis Factor Therapy During Pregnancy on the Course of Inflammatory Bowel Disease and Neonatal Exposure显示文摘 | Zuzana Zelinkova Cokkie van der Ent Karlien F. Bruin Onno van Baalen Hestia G. Vermeulen Herman J.T. Smalbraak Rob J. Ouwendijk Aad C. Hoek Sjoerd D. van der Werf Ernst J. Kuipers C. Janneke van der Woude | 2013 | Clinical Gastroenterology and Hepatology2013，，： | 1 |
| 8 | Mechanical overload-induced apoptosis: A study in cultured neonatal ventricular myocytes and fibroblasts显示文摘 | Marion Persoon-Rothert Karlien G.C. van der Wees Arnoud van der Laarse | 2002 | Molecular and Cellular Biochemistry2002，，1： | 1 |
| 9 | Autologous In Vivo Adipose Tissue Engineering in Hyaluronan-Based Gels—A Pilot Study显示文摘 | Karsten Hemmrich Karlien Van de Sijpe Nicholas P. Rhodes John A. Hunt Chiara Di Bartolo Norbert Pallua Phillip Blondeel Dennis von Heimburg | 2008 | Journal of Surgical Research2008，，1： | 1 |
| 10 | Cardiac Surgery with Cardiopulmonary Bypass in Low-Weight or Preterm Neonates:A Retrospective Study Analyzing Early Outcome显示文摘Background:Most outcome studies in congenital cardiac surgery for“low weight”neonates include patients undergoing surgery without cardiopulmonary bypass(CPB).The primary objective of our study was to identify risk factors for in-hospital mortality in neonates weighing less than 3 Kg and undergoing surgery with CPB.In addition,we compared the effect of early surgery with CPB(before 37W-gestational age(GA))for congenital heart disease to delayed surgery until a corrected GA of 37 weeks in an attempt to promote weight gain.Methods:Retrospective single-center study including all patients operated between 1997 and 2017.Uni-and multivariable analysis were used to analyze outcome.Results:143 patients were included.The median weight was 2.7 Kg and 49(34.3%)weighted<2.5 Kg.80%of the patients were Risk stratification STAT categories≥3.114 patients(80%)were operated without delay(usual timing,median age 9 days),whereas 29 patients(20%)entered a delayed strategy(median age 30 days).In-hospital mortality was 21.7%.By multivariate analysis,dysmaturity,preoperative positive ventilation,post-operative ECMO requirement or resuscitation,and any residual lesion were predictors of in-hospital death.In-hospital mortality in the usual timing group and the delayed group were 21.1%and 24.1%,respectively(p=0.71).In-hospital mortality for neonates operated prior to 37W-GA(n=10)was 27.3%.Conclusions:Predictors of in-hospital mortality in neonates less 3 Kg requiring CPB surgery did not differ from those unveiled in other contemporary studies.Our data demonstrates that a strategy of delaying surgery in selected patients resulted in similar clinical outcome. | Alain J.Poncelet Maureen Peers de Nieuwburgh Stéphane Moniotte Geoffroy de Beco Karlien Carbonez Jean E.Rubay Thierry Detaille Laurent Houtekie Mona Momeni | 2023 | Congenital Heart Disease2023，18，2： | 0 |
| 11 | A Rare Case of Infective Mediastinitis after Melody Valve Implantation显示文摘Pulmonary valve implant is frequently necessary in children and adults with congenital heart disease.Infective endocarditis represents a rare but life-threatening complication after transcatheter pulmonary valve implantation.There are various treatments for native or prosthetic valve endocarditis.Surgical intervention,combined with intravenous antibiotic treatment,is of paramount importance,in case of concomitant mediastinal infection,in order to ensure the radical debridement of all infected tissue,avoiding any recurrent endocarditis.In this report,we describe a rare case of mediastinitis,associated with an infected endocarditis,occurring 8 months after Melody(Medtronic,Minneapolis,USA)valve implant,successfully treated with the implantation of a homograft to reconstruct the right ventricular outflow tract. | Veronica Lorenz Karlien Carbonez Geoffroy de Beco Alain Poncelet | 2022 | Congenital Heart Disease2022，17，2： | 0 |
| 12 | Analysis of Pulmonary Arteries Growth after Initial Shunt Palliation in Neonates and Infants显示文摘Objective:Despite increasing enthusiasm for neonatal repair,patients with ductal-dependent circulation(pulmonary/systemic)or restrictive pulmonary blood flow still require initial palliation.Ductal stenting has emerged as an endovascular approach whereas modified-Blalock-Taussig and central shunt remain surgical references.In this study,we analyzed the relationship between pulmonary artery growth,sites of shunt connection,or antegrade pulmonary blood flow in surgically placed shunts.The need for secondary catheter-based interventions or pulmonary arterioplasty was also investigated.Methods:A retrospective single-center study analyzing 175 patients undergoing surgery for a central or modified-Blalock-Taussig shunt.Outcome growth variables were right pulmonary artery/left pulmonary artery diameters/Z scores,the indexed sum area(right pulmonary artery+left pulmonary artery),and the pulmonary symmetry index.Three imaging modalities were used:angiography,computed tomography,and echocardiography.Results:At baseline,pulmonary arteries were larger in patients with antegrade pulmonary blood flow(Nakata index 137 vs.114,p=0.047)as well as in patients receiving a modified-Blalock-Taussig shunt(Nakata index 138 vs.84,p<0.001).At the time of shunt takedown,both the right pulmonary artery and left pulmonary artery had normalized their diameter.The Nakata index increased from 134 to 233 mm^(2)/m^(2)(p<0.001).The pulmonary artery index remained stable(0.86)over time.During the inter-stage period,shunt-related pulmonary artery stenosis and juxta-ductal stenosis were diagnosed in 16(10%)and 17 patients(11%),respectively.Conclusions:Surgical shunt palliation allows normal pulmonary artery growth.Pulmonary artery stenosis was either shunt-related(10%)or secondary to juxta-ductal stenosis(11%).Close echographic follow-up allows early diagnosis and treatment of juxta-ductal stenosis. | François-Xavier Van Vyve Karlien Carbonez Geoffroy de Beco Stéphane Moniotte Jean ERubay Mona Momeni Laurent Houtekie Alain J.Poncelet | 2023 | Congenital Heart Disease2023，18，5： | 0 |
| 13 | Analysis of Risk Factors for Early Mortality in Surgical Shunt Palliation:Time for a Change?显示文摘Objectives:Over the last decade,neonatal repair has been advocated for many congenital heart diseases.However,specific subgroups of complex congenital heart disease still require temporary palliation for which both surgical and endovascular techniques are currently available.We reviewed our institutional experience with shunt palliation with an emphasis on risk factors for early mortality.Methods:This is a single-center retrospective study on 175 patients undergoing surgery for central shunt or modified Blalock-Taussig shunt.All data were extracted from a prospectively collected computerized database.We identified risk factors for early mortality by uni-and multi-variable analysis.All data were censored at the time of death or shunt take-down operation.Results:Mean age and weight at surgery were 24 days(IQR[7–95])and 3.4 kg(IQR[2.9–4.8]),respectively,with 96 neonates(55%).Most patients had a biventricular heart disease(115 patients,66%),and 51 patients(29.1%)had univentricular heart disease.Thoracotomy was performed in 129 patients(74%).Cardiopulmonary bypass was used in 23 patients(13%).The median intensive care and overall length of stay were 4 days(IQR[2–9])and 18 days(IQR[13–29]),respectively.In-hospital mortality was 8.6%(15/175).By multivariable regression analysis,prematurity(HR 5.6[2.1–14.7]),CPB use(HR 6.7[2.2–18.6]),unplanned<30-day reoperation(HR 3.5[1.2–10])or catheterization(HR 4.5[1.2–16.9])were all significant predictors of early mortality.Conclusions:Procedural-related mortality remains high(8.6%)in surgical shunt palliation.For patients with prematurity,low weight at birth,or if the use of cardiopulmonary bypass is contemplated,alternative endovascular techniques of palliation should be considered together with longitudinal follow-up studies. | François-Xavier Van Vyve Karlien Carbonez Jelena Hubrechts Geoffroy de Beco Jean ERubay Mona Momeni Thierry Detaille Alain J.Poncelet | 2023 | Congenital Heart Disease2023，18，5： | 0 |
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