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| 1 | Tumor differentiation phenotype in gastric differentiated-type tumors and its relation to tumor invasion and genetic alterations显示文摘瞄准:在胃的区分类型的肿瘤澄清在肿瘤区别显型和肿瘤侵略或基因改变之间的关系。方法:我们检验了肿瘤区别在 48 个胃的腺瘤和 171 区分类型的癌的显型,在 APC 和 p53 的变化的存在,和微卫星不稳定性(MSI ) 地位。肿瘤区别显型被检验人的表示决定胃粘蛋白(HGM ) , MUC6, MUC2 和 CD10。肿瘤然后被分类进胃 --(G-) ,胃、肠混合 --( 官方补给 --) ,或肠 --( 我 --) 显型,根据上述标记的免疫确实。在 APC 和 p53 和 MSI 地位的变化的存在也在所有肿瘤被调查。结果:胃的腺瘤显著地与 CD10 表示,我显型肿瘤和 APC 变化的存在被联系,与癌相比(66.7% 对 25.1% , P <
0.0001;56.3% 对 14.6% , P <
0.0001;39.6% 对 14.0% , P <
0.0001,分别地) 并且相反地与 HGM 和 MUC6 和 p53 变化的存在的表情联系了(10.4% 对 62.6% , P <
0.0001;39.6% 对 64.3% , P = 0.003;2.0% 对 26.3% , P = 0.001,分别地) 。APC 变化的频率在比在 HGM 积极的肿瘤, MUC6 积极的肿瘤, CD10 否定的肿瘤和 G 显型肿瘤的 HGM 否定的肿瘤, MUC6 否定的肿瘤, CD10 积极的肿瘤和我显型肿瘤是显著地更高的(32.7% 对 7.1% , P <
0.0001;27.8% 对 14.0% , P = 0.0182;37.3% 对 10.4% , P <
0.0001;并且 38.5% 对 9.5% , P = 0.0017,分别地) 。MSI 的频率在比在 MUC6 否定的肿瘤, CD10 积极的肿瘤和我显型肿瘤的 MUC6 积极的肿瘤, CD10 否定的肿瘤和 G 显型肿瘤是显著地更高的(24.8% 对 6.7% , P = 0.0009;22.2% 对 8.0% , P = 0.0143;并且 28.6% 对 9.6% , P = 0.0353,分别地) 。结论:肿瘤区别显型是仔细与在胃的区分类型的肿瘤的肿瘤侵略和基因改变有关。 | Kimiyasu Yamazaki Yusuke Tajima Reiko Makino Nobukazu Nishino Shigeo Aoki Masanori Kato Masaaki Sakamoto Koji Morohara Tsutomu Kaetsu Mitsuo Kusano | 2006 | World Journal of Gastroenterology2006，12，24： | 9 |
| 2 | Efficacy of traditional herbal medicines in combination with acyclovir against herpes simplex virus type 1 infection in vitro and in vivo显示文摘 | Masahiko Kurokawa Kazuhiko Nagasaka Tatsuji Hirabayashi Shin-ichi Uyama Hideki Sato Takashi Kageyama Shigetoshi Kadota Haruo Ohyama Toyoharu Hozumi Tsuneo Namba Kimiyasu Shiraki | 1995 | Antiviral Research1995，，1： | 3 |
| 3 | Sentinel Node Mapping Guided by Indocyanine Green Fluorescence Imaging in Gastric Cancer显示文摘 | Yusuke Tajima Kimiyasu Yamazaki Yuki Masuda Masanori Kato Daisuke Yasuda Takeshi Aoki Takashi Kato Masahiko Murakami Mitsuharu Miwa Mitsuo Kusano | 2009 | Annals of Surgery2009，，1： | 3 |
| 4 | Indirect inguinal hernia containing portosystemic shunt vessel: A case report显示文摘BACKGROUND Inguinal hernia repair is one of the most common general surgical operations worldwide.We present a case of indirect inguinal hernia containing an expanded portosystemic shunt vessel.CASE SUMMARY We report a 72-year-old man who had a 4 cm×4 cm swelling in the right inguinal region,which disappeared with light manual pressure.Abdominal-pelvic computed tomography(CT)revealed a right inguinal hernia containing an expanded portosystemic shunt vessel,which had been noted for 7 years due to liver cirrhosis.We performed Lichtenstein’s herniorrhaphy and identified the hernia sac as being indirect and the shunt vessel existing in the extraperitoneal cavity through the internal inguinal ring.Then,we found two short branches between the expanded shunt vessel and testicular vein in the middle part of the inguinal canal and cut these branches to allow the shunt vessel to return to the extraperitoneal cavity of the abdomen.The hernia sac was returned as well.We encountered no intraoperative complications.After discharge,groin seroma requiring puncture at the outpatient clinic was observed.CONCLUSION If an inguinal hernia patient has portal hypertension,ultrasound should be used to determine the contents of the hernia.When atypical vessels are visualized,they may be shunt vessels and additional CT is recommended to ensure the selection of an adequate approach for safe hernia repair. | Masahiro Yura Kikuo Yo Asuka Hara Keita Hayashi Yuki Tajima Yasushi Kaneko Hiroto Fujisaki AkiraHirata Kiminori Takano Kumiko Hongo Kimiyasu Yoneyama Motohito Nakagawa | 2021 | World Journal of Clinical Cases2021，9，2： | 2 |
| 5 | Risk Factors for Lymph Node Metastasis from Gastric Cancers with Submucosal Invasion显示文摘 | Yusuke Tajima Masahiko Murakami Kimiyasu Yamazaki Yuki Masuda Shigeo Aoki Masanori Kato Atsushi Sato Satoru Goto Koji Otsuka Takashi Kato | 2010 | Annals of Surgical Oncology2010，，6： | 2 |
| 6 | Efficacy of Thai medicinal plant extracts against herpes simplex virus type 1 infection in vitro and in vivo显示文摘 | Vimolmas Lipipun Masahiko Kurokawa Rutt Suttisri Pagorn Taweechotipatr Pornpen Pramyothin Masao Hattori Kimiyasu Shiraki | 2003 | Antiviral Research2003，，3： | 1 |
| 7 | Prophylactic treatment of cytomegalovirus infection with traditional herbs显示文摘 | Tomoyo A. Yukawa Masahiko Kurokawa Hitoshi Sato Yoshihiro Yoshida Seiji Kageyama Tomomi Hasegawa Tuneo Namba Masami Imakita Toyoharu Hozumi Kimiyasu Shiraki | 1996 | Antiviral Research1996，，2： | 1 |
| 8 | Sentinel Node Mapping Guided by Indocyanine Green Fluorescence Imaging in Gastric Cancer显示文摘 | Yusuke Tajima Kimiyasu Yamazaki Yuki Masuda Masanori Kato Daisuke Yasuda Takeshi Aoki Takashi Kato Masahiko Murakami Mitsuharu Miwa Mitsuo Kusano | 2009 | Annals of Surgery2009，，1： | 1 |
| 9 | Ischemia-induced angiogenesis: role of inflammatory response mediated by P-selectin显示文摘 | Kimiyasu E Toyoaki M Mika A | 2006 | J Leukoc Biol2006，79，5： | 1 |
| 10 | Role of host angiotensin II type 1 receptor in tumor angiogenesis and growth显示文摘 | Kimiyasu E Toyoaki M Toshifumi S | 2003 | The Journal of Clinical Investigation2003，112，1： | 1 |
| 11 | Climate and vegetation changes around Lake Baikal during the last 350,000 years显示文摘 | Koji Shichi Kimiyasu Kawamuro Hikaru Takahara Yoshitaka Hase Takeshi Maki Norio Miyoshi | 2007 | Palaeogeography Palaeoclimatology Palaeoecology2007，，3： | 1 |
| 12 | Application of two types of CIM tube column for purification of microbial enzymes显示文摘 | Isobe Kimiyasu Kawakami Yoshimitsu | 2005 | Journal of Chromatography A Volume: 1065 Issue:1 February2005，11，： | 1 |
| 13 | Circulating p53 Antibody in Patients with Colorectal Cancer显示文摘 | Goshi Shiota Masato Ishida Naoya Noguchi Kenji Oyama Yuji Takano Michiko Okubo Shunsuke Katayama Yasushi Tomie Kenichi Harada Kotaro Hori Kumiyo Ashida Yosuke Kishimoto Akihide Hosoda Takeaki Suou Takamasa Kanbe Kiwamu Tanaka Kimiyasu Nosaka Osamu Tanida | 2000 | Digestive Diseases and Sciences2000，，1： | 1 |
| 14 | Angiogenesis and Vasculogenesis Are Impaired in the Precocious-Aging klotho Mouse显示文摘 | Toshifumi Shimada Yoshiaki Takeshita Toyoaki Murohara Ken-ichiro Sasaki Kimiyasu Egami Satoshi Shintani Yosuke Katsuda Hisao Ikeda Yo-ichi Nabeshima Tsutomu Imaizumi | 2004 | Circulation2004，，9： | 1 |
| 15 | Prediction of resistance to intravenous immunoglobulin treatment in patients with Kawasaki disease显示文摘 | Kimiyasu Egami Hiromi Muta Masahiro Ishii Kenji Suda Yoko Sugahara Motofumi Iemura Toyojiro Matsuishi | 2006 | The Journal of Pediatrics2006，，2： | 1 |
| 16 | Prediction of resistance to intravenous immunoglobulin treatment in patients with Kawasaki disease显示文摘 | Kimiyasu Egami Hiromi Muta Masahiro Ishii Kenji Suda Yoko Sugahara Motofumi Iemura Toyojiro Matsuishi | 2006 | The Journal of Pediatrics2006，，2： | 1 |
| 17 | Inhibitory activity of oxyresveratrol on wild-type and drug-resistant varicella-zoster virus replication in vitro显示文摘 | Pattaraporn Sasivimolphan Vimolmas Lipipun Kittisak Likhitwitayawuid Masaya Takemoto Pornpen Pramyothin Masao Hattori Kimiyasu Shiraki | 2009 | Antiviral Research2009，，1： | 1 |
| 18 | Anti-herpes simplex virus (HSV-1) activity of oxyresveratrol derived from Thai medicinal plant: Mechanism of action and therapeutic efficacy on cutaneous HSV-1 infection in mice显示文摘 | Taksina Chuanasa Jurairatana Phromjai Vimolmas Lipipun Kittisak Likhitwitayawuid Mikiko Suzuki Pornpen Pramyothin Masao Hattori Kimiyasu Shiraki | 2008 | Antiviral Research2008，，1： | 1 |
| 19 | Crystal orientation of hydroxyapatite induced by ordered carboxyl groups 显示文摘 | Kimiyasu S Toshihiro K Yuri K | 2001 | J Colloid Interf Sci2001，240，： | 1 |
| 20 | Sentinel Node Mapping Guided by Indocyanine Green Fluorescence Imaging During Laparoscopic Surgery in Gastric Cancer显示文摘 | Yusuke Tajima Masahiko Murakami Kimiyasu Yamazaki Yuki Masuda Masanori Kato Atsushi Sato Satoru Goto Koji Otsuka Takashi Kato Mitsuo Kusano | 2010 | Annals of Surgical Oncology2010，，7： | 1 |
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