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| 1 | Microstructure and corrosion resistance of ultrasonic micro-arc oxidation biocoatings on magnesium alloy显示文摘The ultrasonic micro-arc oxidation(UMAO)was used to fabricate ceramic coatings on magnesium alloy.UMAO coatings were produced at 60 W input ultrasonic.The effects of the ultrasound on the microstructure,phase composition,elemental distribution and corrosion resistance of the coatings were extensively investigated by scanning electron microscopy(SEM),X-ray diffraction(XRD),energy-dispersive X-ray spectrometry(EDX)and electrochemical workstation.The results showed that ultrasound improved the homogeneous distribution of micro-porous structure.The coatings were mainly composed of MgO ceramic and small amount of calcium and phosphorus with porous structure.The Ca/P ratio of the coatings increased when 60 W ultrasonic was used.The corrosion potential in simulated body fluid(SBF)changed from��1.583 V of bare magnesium alloy to -0.353 V of magnesium alloy coated under 60 W ultrasonic.The corrosion resistance of UMAO coatings was better than that of MAO coatings. | Lijie QU Muqin LI Miao LIU Erlin ZHANG Chen MA | 2013 | Journal of Advanced Ceramics2013，2，3： | 9 |
| 2 | Experimental investigation of ghost imaging of reflective objects with different surface roughness显示文摘We present an experimental demonstration of ghost imaging of reflective objects with different surface roughness.The influence of the surface roughness, the transverse size of the test detector, and the reflective angle on the signal-to-noise ratio(SNR) is analyzed by measuring the second-order correlation of the light field based on classical statistical optics. It is shown that the SNR decreases with an increment of the surface roughness and the detector's transverse size or a decrease of the reflective angle. Additionally, the comparative studies between the rough object and the smooth one under the same conditions are also discussed. | SUQIN NAN YANFENG BAI XIAOHUI SHI QIAN SHEN LIJIE QU HENGXING LI XIQUAN FU | 2017 | Photonics Research2017，5，4： | 5 |
| 3 | Development of indirect competitive immunoassay for highly sensitive determination of ractopamine in pork liver samples based on surface plasmon resonance sensor显示文摘 | LIU Ming NING Baoan QU Lijie | 2012 | Sensors and Actuators B: Chemical2012，161，1： | 1 |
| 4 | Synthesis and Characterization of Poly(N-Hexyl-2, 7-di(2-(4-hexylthiophene)carbazole)显示文摘One conjugated polymer consisting of carbazole and 3-hexylthiophene moiety, poly(N-Hexyl-2,7-di(2-(4-hexylthiophene)carbazole)(PNDC), has been synthesized by ferric chloride oxidative polymerization. The monomer N-Hexyl-2,7-di(2-(4-hexylthiophene)carbazole was synthesized and characterized by IR, 1H-NMR, 13C-NMR and MS. UV-vis absorption spectrum, fluorescence spectrum, photoluminescence spectrum and electrochemical properties of the polymer were investigated. Polymer PNDC shows maximum peak appearing at 394 nm in UV-vis absorption spectrum, strongest fluorescence-emission at 482 nm in fluorescence spectrum and maximum emission peak at 492 nm in photoluminescence spectrum. The band-gap(Eg), HOMO energy(EHOMO), and LUMO energy(ELUMO) of the polymer were obtained as 2.58,-5.32, and-2.74 e V, respectively. | 周勇 刘福德 WU Haiyan DUAN Lijie QU Boyang | 2015 | Journal of Wuhan University of Technology(Materials Science)2015，30，5： | 1 |
| 5 | Development of indirect competitive immunoassay for highly sensitive determination of ractopamine in pork liver samples based on surface plasmon resonance sensor显示文摘 | LIU Ming NING Baoan QU Lijie | 2012 | Sensors and Actuators B2012，161，： | 1 |
| 6 | Development of indirect competitive immunoassay for higtfly sensitive determination of ractopamine in pork liver samples based on surface plasmon resonance sensor 显示文摘 | Liu Ming Ning Baoan Qu Lijie | 2012 | Sens Act B: Chem2012，161，1： | 1 |
| 7 | kdm4aa is required for reproduction and development of zebrafish显示文摘Lysine-specific demethylase 4A(KDM4A)catalyzes demethylation of histone lysine residues,which regulates chromatin state and transcription.In drosophila and mice,KDM4A plays an important role in multiple biological processes including development,aging,metabolism,and immunity,however the functions of KDM4A in fish are still unclear.There are two copies of the kdm4a gene in zebrafish,namely kdm4aa and kdm4ab,kdm4aa was edited using CRISPR/Cas9 technology in the present study,then homozygous kdm4aa mutants(kdm4aa^(-/-)��)were obtained,and loss of kdm4aa was confirmed by sequencing and increased H3K9me3.Whole-mount in situ hybridization showed that kdm4aa is widely expressed during the embryonic development of zebrafish.Compared with WT zebrafish,kdm4aa^(-/-)��zebrafish showed no significant difference in gamete formation and fertilization,but the survival rate of kdm4aa^(-/-)��embryos dramatically reduced to 21%at 26 hpf.Further observation showed that about 80%of survived kdm4aa^(-/-)��zebrafish experienced disruption in stripe formation,and 10%of survived kdm4aa^(-/-)��zebrafish underwent vertebral malformation.Alizarin red S staining demonstrated the abnormal spinal development in kdm4aa^(-/-)��zebrafish.These results indicated that kdm4aa is required for normal embryonic development of zebrafish,loss of kdm4aa function leads to decreased survival during the early stages of zebrafish development and morphological variation in adult zebrafish. | Lijie Han Juntao Luo Songya Qu Xueling Shi Junfang Zhang Bingshe Han | 2023 | Aquaculture and Fisheries2023，8，6： | 0 |
| 8 | Lightweight quasi-layered elastic fibrous porous ceramics with high compressive stress and low thermal conductivity显示文摘Fibrous porous ceramics are attractive for use as thermal insulation materials.However,the intrinsic brit-tleness of rigid materials has remained challenging and severely restricts their applications.Here,we demonstrated a facile method for fabricating elastic fibrous porous ceramics(EFPCs)with high com-pressive strength and low thermal conductivity through ordinary press filtration and subsequent heat treatment.The quasi-layered structure and the well-bonded bridging fibers between layers are the key points for the elasticity of EFPCs.The advanced EFPCs exhibited low density(∼0.126 g cm^(−3)),high com-pressive stress(∼0.356 MPa),and low thermal conductivity(∼0.026 W m^(−1) K^(−1)).Compared with rigid porous fibrous materials,the EFPCs had deformability and excellent shape recovery.In contrast to flexible materials,the EFPCs possessed high compressive stress,thus endowing them with good resistance to de-formation.The emergence of this fascinating material may provide new insights for candidate materials in thermal insulation and other fields. | Ning Zhou Baosheng Xu Zhiliang Zhou Lijie Qu Yiguang Wang Wenbo Han Daining Fang | 2023 | Journal of Materials Science & Technology2023，，12： | 0 |
| 9 | Nitrogen and boron co-doped graphene nanoribbons as peroxidase-mimicking nanozymes for enhanced biosensing显示文摘The rational design of nanozymes with superior activities is essential for improving bioassay performances.Herein,nitrogen and boron co-doped graphene nanoribbons(NB-GNRs)are prepared by a hydrothermal method using urea as the nitrogen source and boric acid as the boron source,respectively.The introduction of co-doped and edge structures provides high defects and active sites.The resultant NB-GNRs nanozymes show superior peroxidase-like activities to nitrogen-doped and boron-doped counterparts due to the synergistic effects.By taking advantage of their peroxidase-like activities,NB-GNRs are used for the first time to develop enzyme-linked immunosorbent assay for the detection of interleukin-6.The biosensors exhibit a high performance with a linear range from 0.001 ng/mL to 1000 ng/mL and a detection limit of 0.3 pg/mL.Due to their low cost and high stability,the proposed nanomaterials show great promise in biocatalysis,immunoassay development and environmental monitoring. | Siyu Luo Meng Sha Fei Tian Xialian Li Lijie Fu Yingqiu Gu Lu-Lu Qu Guo-Hai Yang Chengzhou Zhu | 2022 | Chinese Chemical Letters2022，33，1： | 0 |
| 10 | A Novel Masking Scheme for SM3 Based MAC显示文摘The Chinese hash algorithm SM3 is verified to be secure enough,but improper hardware implementation may lead to leakage.A masking scheme for SM3 algorithm is proposed to ensure the security of SM3 based Message Authentication Code(MAC).Our scheme was implemented in hardware,which utilizes hardware oriented secure conversion techniques between boolean and arithmetic masking.Security evaluation based on SAKURA-G FPGA board has been done with 2000 power traces from 2000 random plaintexts with random plaintext masks and random key masks.It has been verified that the masked SM3 hardware implementation shows no intermediate value leakage as expected.Our masked SM3 hardware can resist first-order correlation power attack(CPA) and collision correlation attack. | QU Kaige WU Liji WANG An REN Yanting ZHANG Xiangmin | 2015 | China Communications2015，12，6： | 0 |
| 11 | 人源大麻素受体CB2的晶体结构显示文摘文章简介大麻素受体CB2主要分布在人体的免疫系统,选择性调控大麻素受体CB2对炎症、纤维化及神经退行性疾病等具有较好的治疗潜力,同时可避免由大麻素受体CB1引起的精神活性。本研究报道了大麻素受体CB2与新型拮抗剂AM0257复合物2.8埃分辨率的晶体结构。经结构对比分析,发现同处于拮抗状态的CB2与CB1不但结构差别极大。 | Xiaoting Li Tian Hua Kiran Vemuri Jo-Hao Ho Yiran Wu Lijie Wu Petr Popov Othman Benchama Nikolai Zvonok K’ara Locke Lu Qu Gye Won Han Malliga R.Iyer Resat Cinar Nathan J.Coffey Jingjing Wang Meng Wu Vsevolod Katritch Suwen Zhao George Kunos Laura M.Bohn Alexandros Makriyannis Raymond C.Stevens 刘志杰 | 2020 | 科学新闻2020，，2： | 0 |
| 12 | Efficacy and mechanisms of Dingxian pill(定痫丸)combined with valproic acid on pentylenetetrazol-induced chronic epilepsy in rats显示文摘OBJECIVE:To investigate the efficacy and mechanisms of Dingxian pill(定痫丸)combined with valproic acid(VPA)on pentylenetetrazol-induced chronical epilepsy in rats.METHODS:A rat model of epilepsy was established by administering pentylenetetrazol(PTZ)water solution(35 mg/kg).Rats were divided into 4 groups,among which three groups were treated with different drugs once a day for 28 d including Dingxian pill(2.4 g/kg),VPA(0.2 g/kg),or a combination of Dingxian pill(2.4 g/kg)and VPA(0.2 g/kg)respectively,and the control group was given the same volume of saline.Rats in different groups were compared based on animal behavior,electroencephalograms,Morris water maze,immunohistochemistry,transcriptomics and real-time polymerase chain reaction.RSULTS:The combination therapy of Dingxian pill and VPA inhibited PTZ-induced seizure-like behavior and reduced seizure grades more significantly than VPA alone.Compared with the control group,the learning and memory ability of chronic PTZ-induced epileptic rats was improved in all the drug treatment groups,especially in the group that received both Dingxian pill and VPA.Similar to the results of MWM tests,expression of the neuroexcitability marker gene c-Fos was reduced after Dingxian pill and/or VPA treatment,and the effect was most pronounced in the combined treatment group.Transcriptomic analysis revealed that gene expression in the rodent hippocampus,which is involved in epilepsy,was upregulated by combined treatment with Dingxian pill and VPA,compared with VPA treatment alone.CONCLUSION:Our results not only highlight the antiepileptic effects of combined Dingxian pill and VPA treatment,but also shed light on the underlying molecular mechanisms and provide a way to apply Traditional Chinese Medicine in the treatment of epilepsy. | QU Dongxiao GE Yiqin ZHUO Limin CHEN Liji XUE Yonghua CHENG Jiwei TAO Jie LI Guoyi ZHU Yudan XIAO Qian | 2023 | Journal of Traditional Chinese Medicine2023，43，2： | 0 |
| 13 | Synthesis and Characterization of Polythiophenes Bearing Diphenyl Groups in the Conjugated Chain显示文摘4,4'-dibromo-2-nitro-biphenyl and 4,4'-dibromo-2,3'-dinitro-biphenyl have been synthesized via nitration reaction with 4,4′-dibromobiphenyl as the raw material. Three novel thiophene derivatives, 4, 4′-di(4-hexyl-thiophen-2-yl)biphenyl, 4,4′-di(4-hexyl-thiophen-2-yl)-2- nitro-biphenyl and 4,4′-di(4-hexyl-thiophen-2-yl)-2,3'-dinitrobiphenyl were synthesized through Stille coupling reaction, followed by polymerization in the presence of Fe Cl3, respectively. UV-vis absorption spectra, fluorescence spectra, photoluminescence spectra and electrochemical properties of the polymers were investigated. And the band-gap(Eg), HOMO orbital energy(EHOMO), and LUMO orbital energy(ELUMO) of the polymers were calculated. Among the polymers, polymer PBTN and PBTD show lower band-gap(2.67 and 2.63 e V), lower HOMO energy level(-5.38 and-5.4 e V) and broader wavelength(432 and 438 nm) than that of polymer PBTB(2.69 e V,-5.36 e V and 424 nm) with incorporation of one nitro group or two nitro groups in the main chain, respectively. | 周勇 刘福德 WU Haiyan QU Boyang DUAN Lijie | 2015 | Journal of Wuhan University of Technology(Materials Science)2015，30，3： | 0 |
| 14 | Structural insights into the activation initiation of full-length mGlu1显示文摘Dear Editor,Glutamate is the main excitatory neurotransmitter in the human brain,and it exerts diverse responses through ionotropic glutamate receptors(iGluRs)and metabotropic glutamate receptors(mGluRs)(Nakanishi and Masu,1994).mGluRs are members of the C family of GPCRs,and are divided into three groups based on G protein coupling,sequence homology,and ligand selectivity(Stansley and Conn,2019).mGlu1 and mGlu5 belong to group I and predominantly couple to Gq/11. | Jinyi Zhang Lu Qu Lijie Wu Xiaomeng Tang Feng Luo Weixiu Xu Yueming Xu Zhi-Jie Liu Tian Hua | 2021 | Protein & Cell2021，12，8： | 0 |
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