|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Evidence chain-based causality identification in herb-induced liver injury: exemplification of a well-known liver-restorative herb Polygonum multiflorum显示文摘草药的药最近在美国作为导致药的肝损害(DILI ) 的第二个很普通的原因被认出了。然而,识别一些植物的 DILI 诱发性的可靠方法例如 Heshouwu (蓼 multiflorum 的弄干的根) ,留下缺乏。在这研究,有肝机能障碍和 Heshouwu DILI 的 147 个报导文学的案例的 12 307 个住院病人的一个总数被屏蔽。一个一般算法仅仅显示了那 22.5%(9/40 ) 并且(45/147 ) 分别地, 30.6% 所有住院和文学案例报告表明 Heshouwu 的 DILI 诱发性的高概率。由对比,(19/20 )95% 生药学,植物化学,和 metabolomic 有希望地调查的所有情况测试展出高度可能的诱发性,包括不正确地以前被归因的一个病人和从由 pharmacognostic 证据的 Heshouwu 诱发性被排除的一个案例。污染也是的毒素(重金属,杀虫剂,和 mycotoxins ) 从 Heshouwu DILI 诱发性排除了。为 Heshouwu DILI 诊断地址安全的这些屏蔽方法的客观性担心考虑包含芪的草药的药和饮食的补充。 | Jiabo Wang Zhijie Ma Ming Niu Yun Zhu Qingsheng Liang Yanling Zhao Jingyuan Song Zhaofang Bai Yaming Zhang Ping Zhang Na Li Yakun Meng Qi Li Lushan Qin Guangju Teng Junling Cao Baosen Li Shilin Chen Yonggang Li Zhengsheng Zou Honghao Zhou Xiaohe Xiao | 2015 | Frontiers of Medicine2015，9，4： | 47 |
| 2 | A genome-wide landscape of mRNAs,lncRNAs,and circRNAs during subcutaneous adipogenesis in pigs显示文摘Background: Preadipocyte differentiation plays a critical role in subcutaneous fat deposition in pigs.However,the roles of different RNAs,such as messenger RNAs(mRNAs),long non-coding RNAs(lncRNAs),and circular RNAs(circRNAs) in the differentiation process of subcutaneous preadipocytes,are still largely unclear.In the present study,a transcriptome analysis,including the analysis of mRNAs,lncRNAs,and circRNAs,during different differentiation stages,namely,day 0(D0),day 2(D2),day 4(D4),and day 8(D8),of subcutaneous preadipocytes from Chinese Erhualian pigs was performed.Results: A total of 1554,470,1344,1777,and 676 differentially expressed(DE) mRNAs,112,58,95,136,and 93 DE lncRNAs,and 902,787,710,932,and 850 DE circRNAs were identified between D2 and D0,between D4 and D2,between D8 and D4,between D4 and D0,and between D8 and D0,respectively.Furthermore,functional enrichment analysis showed that the common DE mRNAs during the entire differentiation process were mainly involved in lipid metabolic and cell differentiation processes.Additionally,co-expression network analysis identified the potential lncRNAs related to adipogenesis,e.g.,MSTRG.131380 and MSTRG.62128.Conclusions: Our study provides new insights of the expression changes of RNAs during adipogenic differentiation,which might contribute to the phenotype of subcutaneous adipogenesis.These results greatly improve our understanding of the molecular mechanisms regulating subcutaneous fat deposition in pigs. | Xin Liu Kaiqing Liu Baosen Shan Shengjuan Wei Dongfeng Li Haiyin Han Wei Wei Jie Chen Honglin Liu Lifan Zhang | 2019 | Journal of Animal Science and Biotechnology2019，10，1： | 5 |
| 3 | Effects of common polymorphisms rs2910164 in miR-146a and rs3746444 in miR-499 on cancer susceptibility: a meta-analysis显示文摘 | Zhihua Yin Lei Yan Zhigang Cui Xuelian Li Yangwu Ren Baosen Zhou | 2013 | Molecular Biology Reports2013，，4： | 1 |
| 4 | Evidence for cigarette smoke-induced oxidative stress in the rat pancreas显示文摘 | Jianyu Hao Guang Li Baosen pang | 2009 | Inhalation Toxicology2009，，12： | 1 |
| 5 | The heat-affected zone microstructure of 12% chromium steel welds 显示文摘 | Baosen W Li M | 2007 | Baosteel Technology2007，132，3： | 1 |
| 6 | Laparoscopic ovarian endometriosis cyst surgery 106cases analysis显示文摘 | Liu Chunxian Li Baosen | 2009 | Journal of Huaxi Medical2009，23，7： | 1 |
| 7 | Quantum key distribution and quantum authentication based on entangled states 显示文摘 | Shi Baosen Li Jian Liu Jinming | 2001 | Physical Letters A2001，281，23： | 1 |
| 8 | 3D printed triboelectric nanogenerator as self-powered human–machine interactive sensor for breathing-based language expression显示文摘Human–machine interfaces(HMIs)are important windows for a human to communicate with the outside world.The current HMI devices such as cellphones,tablets,and computers can be used to help people with aphasia for language expression.However,these conventional HMI devices are not friendly to some particular groups who also lose their abilities of physical movements like in the intensive care unit(ICU)or vegetative patients to realize language expression.Herein,we report a breath-driven triboelectric nanogenerator(TENG)acting as a HMI sensor for language expression through human breathing without voice controls or manual operations.The TENG is integrated within a mask and fabricated via a three-dimensional(3D)printing method.When wearing the mask,the TENG can produce responsive electric signals corresponding to the airflow from breathing,which is capable of recognizing human breathing types with different intensities,lengths,and frequencies.On the basis of the breathing recognition ability,a breathing-based language expressing system is further developed through introducing the Morse code as a communication protocol.Compared with conventional language expressing devices,this system can extract subjective information of a person from breathing behaviors and output corresponding language text,which is not relying on voices or physical movements.This research for the first time introduces the self-powered breathing-based language expressing method to the field of HMI technology by using a 3D printed TENG,and could make HMI interactions become more friendly and fascinating. | Pengcheng Zhu Baosen Zhang Hongyi Wang Yiheng Wu Hengjun Cao Liubing He Chaoyue Li Xuepeng Luo Xing Li Yanchao Mao | 2022 | Nano Research2022，15，8： | 1 |
| 9 | Menstrual Factors,Reproductive Factors and Lung Cancer Risk:A Meta-analysis显示文摘Background and objective Epidemiological studies have suggested that menstrual and reproductive factors may in uence lung cancer risk,but the results are controversial.We therefore carried out a meta-analysis aiming to examine the associations of lung cancer in women with menstrual and reproductive factors.Methods Relevant studies were searched from PubMed database,CNKI,WANFANG DATA and VIP INFORMATION up to January 2012,with no language restrictions.References listed from selected papers were also reviewed.We included studies that reported the estimates of relative risks(RRs) with 95% con dence intervals(CIs) for the association between menstrual and reproductive factors and lung cancer risk.e pooled RRs were calculated a er the heterogeneity test with the so ware Stata 11,and publication bias and sensitivity were evaluated at the same time.Results Twenty-ve articles,representing 24 independent studies,were included in this meta-analysis.Older age at menarche in North America women(RR=0.83;95%CI:0.73-0.94) was associated with a signi cant decreased risk of lung cancer.Longer length of menstrual cycle was also associated with decreased lung cancer risk(RR=0.72;95%CI:0.57-0.90).Other exposures were not signi cantly associated.Conclusions Our analysis provides evidence of the hypothesis that female sex hormones in uence the risk of lung cancer in women,yet additional studies are warranted to extend this nding and to clarify the underlying mechanisms. | Yue ZHANG 1,2,3,Zhihua YIN 1,2,3,Li SHEN 1,2,3,Yan WAN 1,2,3,Baosen ZHOU 1,2,3 1 Department of Epidemiology,School of Public Health,China Medical University,Shenyang 110001,China 2 Key Laboratory of Cancer Etiology and Intervention,Liaoning University,Shenyang 110036,China 3 China Medical University Center For Evidencebased Medicine,Shenyang 110001,China | 2012 | 中国肺癌杂志2012，15，12： | 1 |
| 10 | Imbalanced Intrahepatic Cytokine Expression of Interferon-γ, Tumor Necrosis Factor-α, and Interleukin-10 in Patients With Acute-on-Chronic Liver Failure Associated With Hepatitis B Virus Infection显示文摘 | Zhengsheng Zou Baosen Li Dongping Xu Zheng Zhang Jing-Min Zhao Guangde Zhou Yanling Sun Lei Huang Junliang Fu Yongping Yang Lei Jin Wei Zhang Jun Zhao Ying Sun Shaojie Xin Fu-Sheng Wang | 2009 | Journal of Clinical Gastroenterology2009，，2： | 1 |
| 11 | Association of methylenetetrahydrofolate reductase C677T and A1298Cpolymorphisms with colorectal cancer risk: A meta?analysis显示文摘 | Mengmeng Zhao Xuelian Li Chengzhong Xing Baosen Zhou | 2013 | Biomedical Reports2013，，5： | 1 |
| 12 | Carbide precipitates and mechanical properties of medium Mn steel joint with metal inert gas welding显示文摘Medium Mn steel was metal inert gas(MIG)welded with NiCrMo-3 and 307 Si filler wires.The effect of filler wires on the microstructure and mechanical properties of joint was investigated,and the carbide precipitates were contrastively discussed.The results revealed that the microstructure of weld metal,heat-affected zone and base metal are austenite.Obvious grain coarsening occurred in the heat-affected zone(HAZ),and the maximum grain size grew up to 160μm.In HAZ,C and Cr segregated at grain boundaries,the carbides was identified as Cr7 C3.The dispersive(Nb,Mo)C phase was also found in weld metal with NiCrMo-3 filler wire.All the welded joints failed in HAZ during tensile tests.The tensile strength of welded joint with NiCrMo-3 filler wire was 675 MPa,which is much higher than that with307 Si filler wire.In comparison to base metal,higher microhardness and lower impact toughness were obtained in HAZ for these two welded joints,which was attributed to the precipitation of Cr7 C3 phase and grain coarsening.The impact toughness around the fusion line is the worst for these two welded joints. | Jiang Yang Honggang Dong Yueqing Xia Peng Li Xiaohu Hao Yaqiang Wang Wei Wu Baosen Wang | 2021 | Journal of Materials Science & Technology2021，，16： | 1 |
| 13 | The analysis and forecast for fouling in water pipelines in Daqing oilfield显示文摘 | Xiaoyan LIU Qianya ZHU Jinlai FENG Gang QI Baosen ZHANG Yingli LI Jingxin SUN | 2006 | Chinese Journal Of Geochemistry2006，25，B08： | 0 |
| 14 | Magnetic behaviors and magnetocaloric effects in rare earth high-entropy amorphous/nanocrystalline alloys显示文摘Rare earth high-entropy alloys(RE-HEAs)exhibit great potential to be applied as refrigerants due to their good comprehensive magnetocaloric properties.In this work,octary GdTbDyHoErTmCoAl and GdTbDyHoErTmCoNi RE-HEAs with amorphous/nanocrystalline structure exhibiting comparable magnetocaloric effect were synthesized.Both RE-HEAs show a second-order magnetic phase transition in the temperature range of hydrogen liquefaction.Due to the complex magnetic interactions,a spin glasslike behavior at low temperatures is observed in the RE-HEAs.A superior magnetocaloric effect is obtained in the nanocrystalline GdTbDyHoErTmCoNi high-entropy alloy that is multiphase attributed to a stronger magnetic exchange interaction when compared with the other that exhibits single amorphous structure.Despite heterogeneous microstructure,homogeneous chemical distributions are observed in the partially crystallized high-entropy alloy.In addition,the magnetocaloric effect and magnetic transition behavior of rare earth medium-and high-entropy alloys,including the RE-HEAs in this study,are summarized and discussed.The results in this work provide a helpful guide for the design of RE-HEAs for hydrogen liquefaction applications with excellent magnetocaloric effects. | Lin Xue Liliang Shao Baosen Zhang Zongzhen Li Jiangbo Cheng Baolong Shen | 2024 | Journal of Rare Earths2024，42，1： | 0 |
| 15 | Superconductivity above 70 K observed in lutetium polyhydrides显示文摘The binary polyhydrides of heavy rare earth lutetium that shares a similar valence electron configuration to lanthanum have been experimentally discovered to be superconductive.The lutetium polyhydrides were successfully synthesized at high pressure and high temperature conditions using a diamond anvil cell in combinations with the in-situ high pressure laser heating technique.The resistance measurements as a function of temperature were performed at the same pressure of synthesis in order to study the transitions of superconductivity(SC).The superconducting transition with a maximum onset temperature(Tc)71 K was observed at pressure of 218 GPa in the experiments.The Tcdecreased to 65 K when pressure was at 181 GPa.From the evolution of SC at applied magnetic fields,the upper critical field at zero temperatureμ0Hc2(0)was obtained to be~36 T.The in-situ high pressure X-ray diffraction experiments imply that the high TcSC should arise from the Lu4H23phase with Pm3n symmetry that forms a new type of hydrogen cage framework different from those reported for previous light rare earth polyhydride superconductors. | Zhiwen Li Xin He Changling Zhang Ke Lu Baosen Min Jun Zhang Sijia Zhang Jianfa Zhao Luchuan Shi Yi Peng Shaomin Feng Zheng Deng Jing Song Qingqing Liu Xiancheng Wang Richeng Yu Luhong Wang Yingzhe Li Jay D.Bass Vitali Prakapenka Stella Chariton Haozhe Liu Changqing Jin | 2023 | Science China(Physics,Mechanics & Astronomy)2023，66，6： | 0 |
| 16 | Anomalous eastward displacement of the tropical western Pacific warm pool and warming of the tropical eastern Pacific显示文摘Based on the data from the Climate Diagnostics Bulletin, Oceanographic Monthly Summary, UH Sea Level Center and TOGA─COARE IOP, the response of warm pool in the tropical western Pacific and the tropical eastern Pacific SST to the anomalous wind field during 1992/1993 EI Nino has been analyzed. The results show that the eastward transport of warm water of the tropical western Pacific due to the westerly wind burst leads not only to a drop of sea level but also to a raise of thermocline in the tropical western Pacific. Consequently the heat content in upper layer water decreases especially in the thermocline. Contrary to this, the positive anomalies Of heat content and thermocline depth appear in the tropical eastern Pacific. The positive anomalies in the eastern Pacific lag the negative ones in the western Pacific by two months; The anomalous eastward shift of warm pei (28℃isotherm) is a direct response of ocean current to westerly wind anomalies in low-level atmosphere; quantitative calculations show that the thermal advection caused by anomalous ocean current is the main force of anomalous eastward displacement of the warm pool (28℃isotherm) and the one of main causes for anomalous warming of the tropical eastern Pacific. | Long Baosen Li Bocheng and Zou Emei | 1999 | Acta Oceanologica Sinica1999，18，1： | 0 |
| 17 | Single-material-substrated triboelectric–electromagnetic hybrid generator for self-powered multifunctional sensing in intelligent greenhouse显示文摘The environmental micro-energy harvested by the triboelectric–electromagnetic hybrid generator(TEHG)can power sensors and Internet of Things(IoT)nodes in smart agriculture.However,the separation structure of traditional TEHG raises the complexity of form and material,which is harmful to the miniaturization of the device.Herein,a single-material-substrated triboelectric–electromagnetic hybrid generator(SMS-TEHG)based on the flexible magnets is designed to achieve the structural integration of triboelectric nanogenerator(TENG)and electromagnetic generator(EMG).The flexible magnets serve as the electropositive triboelectric materials for TENG and the magnetic materials for EMG,simplifying the structural complexity of TEHG.The open-circuit voltage(VOC)of the TENG and EMG are 187.2 and 9.0 V at 300 rpm,respectively.After 30,000 cycles of stability testing,the VOC of the TENG and EMG retain about 95.6%and 99.3%,respectively.Additionally,the self-powered applications driven by SMS-TEHG in intelligent greenhouse have been successfully demonstrated,such as crop light supplementation,rain monitoring,and wireless temperature and humidity sensing.This work provides a new design for TEHG and possibilities for applying TEHG and IoT in smart agriculture. | Baosen Zhang Wenbo Li Jianwei Ge Chenggen Chen Xin Yu Zhong Lin Wang Tinghai Cheng | 2023 | Nano Research2023，16，2： | 0 |
| 18 | Note on a Conjecture of Gopakumar-Vafa显示文摘我们改述 Gopakumar-Vafa 以纯尺寸的 moduli 的虚拟学位在 Calabi-Yau threefolds 的类零 Gromov-Witteninvariants 上推测一稳定的绳轮并且为 K3 fibred 本地人 Calabi-Yau threefolds 调查 conjecture。 | Jun LI Baosen WU | 2006 | Chinese Annals of Mathematics,Series B2006，27，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员