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| 1 | Guidelines on multidisciplinary approaches for the prevention and management of diabetic foot disease(2020 edition)显示文摘In recent years,as living standards have continued to improve,the number of diabetes patients in China,along with the incidence of complications associated with the disease,has been increasing.Among these complications,diabetic foot disease is one of the main causes of disability and death in diabetic patients.Due to the differences in economy,culture,religion and level of medical care available across different regions,preventive and treatment methods and curative results for diabetic foot vary greatly.In multidisciplinary models built around diabetic foot,the timely assessment and diagnosis of wounds and appropriate methods of prevention and treatment with internal and external surgery are key to clinical practice for this pathology.In 2019,under the leadership of the Jiangsu Medical Association and Chinese Diabetes Society,the writing group for the Guidelines on multidisciplinary approaches for the prevention and management of diabetic foot disease(2020 edition)was established with the participation of scholars from the specialist areas of endocrinology,burn injury,vascular surgery,orthopedics,foot and ankle surgery and cardiology.Drawing lessons from diabetic foot guidelines from other countries,this guide analyses clinical practices for diabetic foot,queries the theoretical basis and grades and gives recommendations based on the characteristics of the pathology in China.This paper begins with assessments and diagnoses of diabetic foot,then describes treatments for diabetic foot in detail,and ends with protections for high-risk feet and the prevention of ulcers.This manuscript covers the disciplines of internal medicine,surgical,nursing and rehabilitation and describes a total of 50 recommendations that we hope will provide procedures and protocols for clinicians dealing with diabetic foot. | Aiping Wang Guozhong Lv Xingbo Cheng Xianghua Ma Wei Wang Jianchao Gui JiHu Meng Lu Guoping Chu Jin’an Chen Hao Zhang Yiqiu Jiang Yuedong Chen Wengbo Yang Lin Jiang Houfa Geng Rendong Zheng Yihui Li Wei Feng Boey Johnson Wenjuan Wang Dalong Zhu Yin Hu | 2020 | Burns & Trauma2020，8，1： | 34 |
| 2 | Effect of composite supports on the methanation activity of Co-Mo-based sulphur-resistant catalysts显示文摘The effects of composite supports of CeO2-Al2O3,MgO-Al2O3,TiO2-Al2O3 or ZrO2-Al2O3 on the methanation activity of supported Co-Mo-based sulphur-resistant catalysts were investigated.The catalysts were further characterized by nitrogen adsorption measurement,X-ray diffraction and X-ray photoelectron spectroscopy.The catalyst of 5%CoO-15%MoO3 supported on CeO2-Al2O3,MgO-Al2O3,TiO2-Al2O3 or ZrO2-Al2O3 composite oxides,respectively,showed different catalytic performances of syngas methanation in the presence of hydrogen sulphide as compared with that of the 5%CoO-15%MoO3/Al2O3 catalyst.The Co-Mo/CeO2-Al2O3 catalyst shows the highest methanation activity among the tested catalysts.The enhanced methanation activity may be attributed to the improvement of the dispersion of active metal species and the inhibition of the formation of S6+. | Haiyang Wang Zhenhua Li Erdong Wang Can Lin Yuguang Shang Guozhong Ding Xinbin Ma Shaodong Qin Qi Sun | 2012 | Journal of Natural Gas Chemistry2012，21，6： | 15 |
| 3 | Integration of micro-supercapacitors with triboelectric nanogenerators for a flexible self-charging power unit显示文摘便携式、便携的电子设备的快速的发展为灵活、有效的精力收获和存储单位增加了需求。通常,这些作为分离部件独立被造并且使用。此处,我们建议雕刻的简单、划算的激光为制作一个灵活自我控告的 micro-supercapacitor 力量单位(SCMPU ) 的技术,由集成摩擦电, nanogenerator (TENG ) 和 micro-supercapacitor (MSC ) 穿进一台单个设备。SCMPU 能被周围的机械运动直接控告。我们表明 SCMPU 的能力连续地驱动轻射出的二极管和商业温湿计。这调查可以支持持续自我动力的系统的开发并且为 supercapacitors 提供一个有希望的新研究应用程序。 | Jianjun Luo Feng Ru Fan Tao Jiang Zhiwei Wang Wei Tang Cuiping Zhang Mengmeng Liu Guozhong Cao Zhong Lin Wang | 2015 | Nano Research2015，8，12： | 14 |
| 4 | 3-year Treatment of Tenofovir Alafenamide vs.Tenofovir Disoproxil Fumarate for Chronic HBV Infection in China显示文摘Background and Aims:Tenofovir alafenamide(TAF)has similar efficacy to tenofovir disoproxil fumarate(TDF)but with improved renal and bone safety in chronic hepatitis B patients studied outside of China.We report 3-year results from two phase 3 studies with TAF in China(Clinicaltrials.gov:NCT02836249 and NCT02836236).Methods:Chinese hepatitis B e antigen(HBeAg)-positive and-negative chronic hepatitis B patients with viremia and elevated alanine aminotransferase were randomized 2:1 to TAF or TDF treatment groups and treated in a double-blind fashion for 144 weeks(3 years).Efficacy responses were assessed by individual study while safety was assessed by a pooled analysis.Results:Of the 334 patients(180 HBeAg-positive and 154 HBeAg-negative)randomized and treated,baseline characteristics were similar between groups.The overall mean age was 38 years and 73%were male.The mean HBV DNA was 6.4 log10 IU/mL.The median alanine aminotransferase was 88 U/L,and 37%had a history of antiviral use.At week 144,the proportion with HBV DNA<29 IU/mL was similar among the two groups,with TAF at 83%vs.TDF at 79%,and TAF at 93%vs.TDF at 92%for the HBeAg-positive and-negative patients,respectively.In each study,higher proportions of TAF than TDF patients showed normalized alanine aminotransferase(via the American Association for the Study of Liver Diseases and the China criteria)and showed loss of HBsAg;meanwhile,the HBeAg seroconversion rates were similar.Treatment was well-tolerated among the TAF patients,who showed a smaller median decline in creatinine clearance(−0.4 vs.−3.2 mL/min;p=0.014)and less percentage change in bone mineral density vs.TDF at hip(−0.95%vs.−1.93%)and spine(+0.35%vs.−1.40%).Conclusions:In chronic hepatitis B patients from China,TAF treatment provided efficacy similar to TDF but with better renal and bone safety at 3 years. | Jinlin Hou Qin Ning Zhongping Duan You Chen Qing Xie Fu-Sheng Wang Lunli Zhang Shanming Wu Hong Tang Jun Li Feng Lin Yongfeng Yang Guozhong Gong John FFlaherty Anuj Gaggar Shuyuan Mo Cong Cheng Gregory Camus Chengwei Chen Yan Huang Jidong Jia Mingxiang Zhang GS-US-320-0110 and GS-US-320-0108 China Investigators | 2021 | Journal of Clinical and Translational Hepatology2021，9，3： | 7 |
| 5 | Accuracy Analysis of Low Altitude Photogrammetry with Wide-angle Camera显示文摘Firstly,the relationship between the accuracy of low altitude aerial photogrammetry and the field angle of camera is made by a quantitative analysis from the theory.The conclusion that the low altitude photogrammetry should use wide-angle camera as much as possible is done.Then,the limitation of the single lens camera to expand field angle and the combined wide-angle camera existing on the market not suitable for light load of low altitude UAV(Unmanned Aerial Vehicle)due to excessive weight are pointed out.The characteristics of combined wide-angle low altitude light camera with self-calibration and self-stabilization developed by the author are described,especially the principle of self-calibration for the combination of static error and dynamic error.Based on the practice of large scale mapping,a technical procedure in aerial photography by taking with wide-angle camera and large overlap simultaneously for improving the accuracy of low altitude photogrammetry is proposed.The typical engineering produced data is used to verity the above theoretical analysis.A technical route for increasing accuracy of low altitude photogrammetry with combined wide-angle camera is expounded. | Zongjian LIN Feifei XIE Guozhong SU | 2018 | Journal of Geodesy and Geoinformation Science2018，1，1： | 5 |
| 6 | 96-Week Treatment of Tenofovir Amibufenamide and Tenofovir Disoproxil Fumarate in Chronic Hepatitis B Patients显示文摘Background and Aims:Tenofovir amibufenamide(TMF)is a novel phosphoramidated prodrug of tenofovir with nonin-ferior efficacy and better bone and renal safety to tenofovir disoproxil fumarate(TDF)in 48 weeks of treatment.Here,we update 96-week comparison results.Methods:Patients with chronic hepatitis B were assigned(2:1)to receive either 25 mg TMF or 300 mg TDF with matching placebo for 96 weeks.The virological suppression was defined as HBV DNA levels<20 IU/mL at week 96.Safety was evaluated thoroughly with focusing on bone,renal,and metabolic pa-rameters.Results:Virological suppression rates at week 96 were similar between TMF and TDF group in both HBeAg-positive and HBeAg-negative populations.Noninferior efficacy was maintained in the pooled population,while it was first achieved in patients with HBV DNA≥7 or 8 log10 IU/mL at baseline.Non-indexed estimated glomerular filtration rate for renal safety assessment was adopted,while a smaller decline of which was seen in the TMF group than in the TDF group(p=0.01).For bone mineral density,patients receiv-ing TMF displayed significantly lower reduction levels in the densities of spine,hip,and femur neck at week 96 than those receiving TDF.In addition,the lipid parameters were stable after week 48 in all groups while weight change still showed the opposite trend.Conclusions:TMF maintained similar efficacy at week 96 compared with TDF with continued superior bone and renal safety profiles(NCT03903796). | Zhihong Liu Qinglong Jin Yuexin Zhang Guozhong Gong Guicheng Wu Lvfeng Yao Xiaofeng Wen Zhiliang Gao Yan Huang Daokun Yang Enqiang Chen Qing Mao Shide Lin Jia Shang Huanyu Gong Lihua Zhong Huafa Yin Fengmei Wang Peng Hu Qiong Wu Chao Pan Wen Jia Chuan Li Chang’an Sun Junqi Niu Jinlin Hou TMF Study Group | 2023 | Journal of Clinical and Translational Hepatology2023，11，3： | 3 |
| 7 | Converting Co^(2+)-impregnated g-C_(3)N_(4) into N-doped CNTs-confined Co nanoparticles for efficient hydrogenation rearrangement reactions of furanic aldehydes显示文摘The cyclopentanone and derivatives are a class of crucial fine chemicals for various industries and currently produced by conventional petrochemical synthetic routes.Here,we demonstrated a new synthetic approach to directly fabricate N-doped carbon nanotube(N-CNTs)networks with confined Co nanoparticles from Co^(2+)-impregnated bulk g-C_(3)N_(4) as high performance hydrogenation rearrangement(HR)catalyst to efficiently convert a wide spectrum of biomass-derived furanic aldehydes to the corresponding cyclopentanones in water under a record-low H2 pressure of 0.5 MPa and mild temperature.We unveiled a Co-catalysed bulk g-C_(3)N_(4) decomposition/carbonisation CNTs formation mechanism.A new HR pathway was also unveiled. | Dongdong Wang Mohammad Al-Mamun Wanbing Gong Yang Lv Chun Chen Yue Lin Guozhong Wang Haimin Zhang Huijun Zhao | 2021 | Nano Research2021，14，8： | 2 |
| 8 | Clinical study on the related markers of blood coagulation in the patients with ANFH after SARS显示文摘The aim of this research was to investigate the blood coagulation function in the patients with avascular necrosis of the femoral head(ANFH)after severe acute respiratory syndrome(SARS).The expression of CD31,CD61,CD62p,CD63 and PAC-1 on platelet membrane was measured respectively by flowcytometry,and the plasma prothrombin time(PT),activated partial thromboplastin time(APTT),thrombin time(TT)and fibrinogen(Fbg)were mea-sured by blood clotting instrument in 26 patients with ANFH after SARS and in 17 healthy adults.The expression of CD31,CD61,CD 62p,CD63 and PAC-1 on platelet membrane in 26 patients was all lower than that in 17 healthy subjects(P<0.01).The levels of PT,APTT,TT and Fbg in 26 patients were all normal.There is no significant difference(P>0.05)in those markers between patients and 17 healthy adults.The blood may not be in hypercoagulable state in patients with ANFH after SARS. | WU Lianhua GAO Chunjin WANG Guozhong YANG Lin HOU Xiaomin GE Huan XIA Chengqing QI Man | 2007 | Frontiers of Medicine2007，1，4： | 2 |
| 9 | Disease severity dictates SARS-CoV-2-specific neutralizing antibody responses in COVID-19显示文摘COVID-19 patients exhibit differential disease severity after SARS-CoV-2 infection.It is currently unknown as to the correlation between the magnitude of neutralizing antibody(NAb)responses and the disease severity in COVID-19 patients.In a cohort of 59 recovered patients with disease severity including severe,moderate,mild,and asymptomatic,we observed the positive correlation between serum neutralizing capacity and disease severity,in particular,the highest NAb capacity in sera from the patients with severe disease,while a lack of ability of asymptomatic patients to mount competent NAbs.Furthermore,the compositions of NAb subtypes were also different between recovered patients with severe symptoms and with mild-tomoderate symptoms.These results reveal the tremendous heterogeneity of SARS-CoV-2-specific NAb responses and their correlations to disease severity,highlighting the needs of future vaccination in COVID-19 patients recovered from asymptomatic or mild illness. | Xiangyu Chen Zhiwei Pan Shuai Yue Fei Yu Junsong Zhang Yang Yang Ren Li Bingfeng Liu Xiaofan Yang Leiqiong Gao Zhirong Li Yao Lin Qizhao Huang Lifan Xu Jianfang Tang Li Hu Jing Zhao Pinghuang Liu Guozhong Zhang Yaokai Chen Kai Deng Lilin Ye | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 1 |
| 10 | Distribution,Seismic Characteristics and Controlling Factors of Carbonate Platforms on the Northwestern Margin of the South China Sea显示文摘Newly-acquired seismic data reveal widespread carbonate deposits covering a large part of the northwestern South China Sea margin.Three carbonate platforms are identified to have developed on the topographic highs inherited from tectonic deformation and volcanic accretion.Across the carbonate platforms,the Miocene strata are characterized by high-amplitude seismic reflections and distinct platform architecture that overlaps older strata.The Guangle and Xisha carbonate platforms grew on faulted blocks due to South China Sea continental rifting,while the Zhongjian carbonate platform developed on a structural high induced by early Miocene volcanism.During the late Miocene,partial drowning resulted in the inhibition of platform growth,eventual platform drowning and termination of most carbonate deposition.The drowning of the Guangle and Zhongjian carbonate platforms is shown by the supply of siliciclastic sediments during the late Miocene and seems to be closely linked to late Neogene volcanic activity,whilst the drowning of the Xisha carbonate platform is primarily related to relative eustatic changes.Our results imply that tectonic activity,volcanism and eustasy are the dominant controls on the evolution of carbonate platforms on the northwestern margin of the South China Sea. | LI Lin WANG Bin YANG Taotao YANG Zhili LI Li LU Yintao WANG Xuefeng WU Jingwu SUN Guozhong | 2021 | Acta Geologica Sinica(English Edition)2021，95，1： | 1 |
| 11 | Preparation and pervaporation property of chitosan membrane with functionalized multiwalled carbon nanotubes 显示文摘 | Qiu Shi Wu Liguang Shi Guozhong Zhang Lin Chen Huanlin Gao Congjie | 2010 | Industrial & Engineering Chemistry Research2010，49，11： | 1 |
| 12 | Receptor for advanced glycation end products (RAGE) partially mediates HMGB1-ERKs activation in clear cell renal cell carcinoma显示文摘 | Liguo Lin Kaihua Zhong Zhongkai Sun Guozhong Wu Guodong Ding | 2012 | Journal of Cancer Research and Clinical Oncology2012，，1： | 1 |
| 13 | Sound propagation in complicated industrial enclosures显示文摘In this article a math model for sound propagation in industrial enclosures is discussed. The model can be applied to an industrial enelosure with any shape, any boundary condition and any obstacles in it. The original purpose of developing this model is only to predict the noise field in power plants, but the results of measurement of sound propagation in power plant workshops indicate that this model has high predication accuracy and can he adanted to various kinds of complicated industrial enclosures. | LIN Guozhong SHI Jianwu and XU Xianjin(Institute for Labour Protection, Power Ministry, Yichang 443002) | 1994 | Chinese Journal of Acoustics1994，13，4： | 0 |
| 14 | Analysis of Autocorrelation Associated with Spatial Sampling Estimation on Urban Greenland Coverage显示文摘By taking the urban greenland as testing objective,the GeoEye-1 fusion image as background, and using Moran’s index,the correlativity of greenland units has been measured.Then,the presampling was conducted based on the measured correlativity,the systematic sampling design has been carried out at the precision 95%and 85%.By using of Kriging interpolation method,the weight of different type of greenland has been divided into the stratifications.Through the stratified sampling,the estimation of greenland coverage has been obtained. The results show that the urban greenland coverage area is 14.81 km^2,accounting for 27.73%of all urban land areas.Compared with the common sampling method,the precision of that increased about 3%. This method can also be utilized in monitoring dynamic variation of urban greenland with the real time images. | Sun Haohan She Guanghui Wen Xiaorong Lin Guozhong | 2012 | Chinese Forestry Science and Technology2012，11，3： | 0 |
| 15 | Estimation and Analysis of Green Land Variation Based on Similarity Theory显示文摘The similarity theory was systematically introduced,by combining the theory and the analytic hierarchy process(AHP),and taking the dynamic changes of two-stage green land patches in Shenzhen as an example,the patches similarity of each district and each green land type were estimated.The location,shape and areas of green land unit were used as the similarity elements.Then the similarity coefficients can be defined.The overlapping number of green land patches indicated the location variation of green land.The ratio of minimum and maximum shape index of green land indicated the shape variation of green land.With the same method,the areas variation coefficient was also obtained.The results shows that based on similarity theory and method the estimation of green land variation is feasible,which can provide effective methods and accordance for the further assessment of green land development in Shenzhen Special Economic Zone. | Wang Fang Wen Xiaorong Lin Guozhong She Guanghui | 2012 | Chinese Forestry Science and Technology2012，11，3： | 0 |
| 16 | Oxygen‑Coordinated Single Mn Sites for Efficient Electrocatalytic Nitrate Reduction to Ammonia显示文摘Electrocatalytic nitrate reduction reaction has attracted increasing attention due to its goal of low carbon emission and environmental protection.Here,we report an efficient NitRR catalyst composed of single Mn sites with atomically dispersed oxygen(O)coordination on bacterial cellulose-converted graphitic carbon(Mn-O-C).Evidence of the atomically dispersed Mn-(O-C_(2))_(4)moieties embedding in the exposed basal plane of carbon surface is confirmed by X-ray absorption spectroscopy.As a result,the as-synthesized Mn-O-C catalyst exhibits superior NitRR activity with an NH_(3)yield rate(RNH_(3))of 1476.9±62.6μg h^(−1)cm^(−2)at−0.7 V(vs.reversible hydrogen electrode,RHE)and a faradaic efficiency(FE)of 89.0±3.8%at−0.5 V(vs.RHE)under ambient conditions.Further,when evaluated with a practical flow cell,Mn-O-C shows a high RNH_(3)of 3706.7±552.0μg h^(−1)cm^(−2)at a current density of 100 mA cm−2,2.5 times of that in the H cell.The in situ FT-IR and Raman spectroscopic studies combined with theoretical calculations indicate that the Mn-(O-C_(2))_(4)sites not only effectively inhibit the competitive hydrogen evolution reaction,but also greatly promote the adsorption and activation of nitrate(NO_(3)^(−)),thus boosting both the FE and selectivity of NH_(3)over Mn-(O-C_(2))_(4)sites. | Shengbo Zhang Yuankang Zha Yixing Ye Ke Li Yue Lin Lirong Zheng Guozhong Wang Yunxia Zhang Huajie Yin Tongfei Shi Haimin Zhang | 2024 | Nano-Micro Letters2024，16，1： | 0 |
| 17 | Evaluation of Medical Malpractice Litigations in China, 2002–2011显示文摘In the past 10 years,medical malpractice litigations have become a serious public health and social issues in China.This study aims to evaluate the medical malpractice litigations in Beijing.A retrospective study was conducted using the database from the Key Laboratory of Evidence Science(KLES)at China University of Political Science and Law(CUPL)to demonstrate the extent and characteristics of the alleged medical malpractice cases and the conclusions of forensic evaluation from 2002 to 2011 in Beijing.A total of 1515 alleged medical malpractice cases were investigated by forensic medical experts at KLES‑CUPL during the study period.Of the 1515 cases,45.2%were male patients and 54.8%were female patients.The age of the patients ranged from newborn to 90 years,with average age of 44 years.The alleged medical malpractice cases involved 11.3%of newborns.From 2002 to 2006,the average number of medical malpractice litigations was 123 cases per year,while from 2007 to 2011,the average number of medical malpractice litigations was 180 per year,a 46%increase.Of the 1515 cases,588(38.8%)litigations were due to the patients’death.Clinical departments involved in claims most often were obstetrics(18.9%),followed by orthopedics(15.1%)and general surgery(11.5%).Medical error was found in 945(62.4%)cases.Of the 945 confirmed medical malpractice cases,the top medical misadventures were diagnostic errors(36.5%),improper performance of procedures(36.4%),and medication error(12.6%).Although tertiary hospitals were more likely to be sued than the secondary and primary hospitals(63.6%vs.36.4%),there was no significant difference between tertiary and secondary hospitals in the percentage of confirmed malpractice cases(62.3%vs.59.4%).The primary hospitals had the highest confirmed malpractice cases(73.2%). | Tiantong Yang Guozhong Zhang Xu Wang Shengli Di Haidong Zhang Daming Sun Siyang Xiang Dong Zhao Lin Chang Ling Li | 2016 | Journal of Forensic Science and Medicine2016，2，4： | 0 |
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