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| 1 | Cadmium accumulation and tolerance of two castor cultivars in relation to antioxidant systems显示文摘To investigate the effects of Cd on tolerance and antioxidant activities of castor, two different castor(Ricinus communis L.) cultivars(Zibo No. 5 and Zibo No. 8) were used for a hydroponic experiment(0, 1 and 2 mg/L Cd) and a pot experiment using Cd-contaminated soil(34 mg/kg) with the addition of ethylenedinitrilotetraacetic acid(EDTA). The results indicated that there were significant differences between the two cultivars with respect to Cd uptake in shoots(113–248 mg/kg for Zibo No. 5 and 130–288 mg/kg Zibo No. 8), biomass tolerance indexes(64.9%–74.6% for Zibo No. 5 and 80.1%–90.9% for Zibo No. 8) in the hydroponic experiment and survival rates(0% for Zibo No. 5 and 100% for Zibo No. 8)determined by the addition of EDTA in the pot experiment, suggesting that Zibo No. 8 has higher tolerance than Zibo No. 5. Moreover, the castor cultivars have low bioconcentration factors(4.80% for Zibo No. 5 and 5.43% for Zibo No. 8) and low translocation factors(<1%).Consequently, Zibo No. 8 can participate in Cd phytostabilization in highly Cd-polluted areas. The results indicated that glutathione(GSH) as a non-enzymatic antioxidant, and antioxidant enzymes including superoxide dismutase(SOD), catalase(CAT) and guaiacol peroxidase(GPX), were cultivar- and dose-dependent. The higher tolerance of Zibo No. 8compared with Zibo No. 5 can be attributed to the higher GSH levels in the root and higher GPX activity in the leaf. | Hanzhi Zhang Qingjun Guo Junxing Yang Tongbin Chen Guangxu Zhu Marc Peters Rongfei Wei Liyan Tian Chunyu Wang Deyun Tan Jie Ma Gangming Wang Yingxin Wan | 2014 | Journal of Environmental Sciences2014，26，10： | 15 |
| 2 | Application of Pb isotopic tracing technique to constraining the source of Pb in the West Lake Longjing tea显示文摘This paper dealt with the Pb contents and Pb isotopic composition of the West Lake Longjing tea. The results showed that in the tea leaves, from young leaf →old leaf →tea limb, the Pb contents tend to increase gradu-ally from 1.63 →4.84 →6.07×10-6, wich revealed that the Pb was accumulated gradually in the tea. After cleaned, the Pb contents of tea leaves were significantly reduced. This indicated that the deposits on the surface of tea leaves made a great contributuion to Pb contents. The survey results for soils in the relevant tea gardens showed that soil from the Longjing tea garden has higher Pb contents, with an average level of 49.6×10-6, two times those of common soils (24×10-6) in China. Results of the systematic analysis for tea, tea garden soil and the samples with the relevant background of the Pb isotopic composition displayed that the Pb isotopic ratio of tea is 206Pb/207Pb=1.164±0.005 (2σ). The ratio of 206Pb/207Pb for the soil gradually decreased from residue phase, soil dilute acid extract phase, and then to urban topsoil, i.e., 1.175 →1.171 →1.170. The 208Pb/(206Pb+207Pb) ratios also show a similar variation trend. 206Pb/207Pb ratios in the samples with the relevant background were: vehicle exhaust, 1.124; coal-combustion, 1.156; atmosphere, 1.168; and water, 1.166. Comparative studies have shown that Pb pollution is popular in the environ-mental media (soil, atmosphere, water) in Hangzhou. With the aggravation of Pb pollution, the Pb isotopic composi-tion gradually changed from the natural background (soil residues) to the direction of automobile exhaust. This phe-nomenon could illustrate that the pollution source was the vehicle exhaust, while the coal-combustion contributed little to environmental pollution in Hangzhou. The Pb of the Longjing tea came mostly from soluble phase Pb in the polluted soil. Moreover, secondary pollution was caused by vehicle exhaust. | LU Yuanfa YANG Hongmei MA Liyan CHEN Xiqing WANG Qunying | 2011 | Chinese Journal Of Geochemistry2011，30，4： | 13 |
| 3 | Analysis of genetic architecture and favorable allele usage of agronomic traits in a large collection of Chinese rice accessions显示文摘Genotyping and phenotyping large natural populations provide opportunities for population genomic analysis and genome-wide association studies(GWAS). Several rice populations have been re-sequenced in the past decade;however, many major Chinese rice cultivars were not included in these studies. Here, we report large-scale genomic and phenotypic datasets for a collection mainly comprised of 1,275 rice accessions of widely planted cultivars and parental hybrid rice lines from China. The population was divided into three indica/Xian and three japonica/Geng phylogenetic subgroups that correlate strongly with their geographic or breeding origins. We acquired a total of 146 phenotypic datasets for 29 agronomic traits under multi-environments for different subpopulations. With GWAS, we identified a total of 143 significant association loci, including three newly identified candidate genes or alleles that control heading date or amylose content. Our genotypic analysis of agronomically important genes in the population revealed that many favorable alleles are underused in elite accessions, suggesting they may be used to provide improvements in future breeding efforts. Our study provides useful resources for rice genetics research and breeding. | Xiuxiu Li Zhuo Chen Guomin Zhang Hongwei Lu Peng Qin Ming Qi Ying Yu Bingke Jiao Xianfeng Zhao Qiang Gao Hao Wang Yunyu Wu Juntao Ma Liyan Zhang Yongli Wang Lingwei Deng Shanguo Yao Zhukuang Cheng Diqiu Yu Lihuang Zhu Yongbiao Xue Chengcai Chu Aihong Li Shigui Li Chengzhi Liang | 2020 | Science China(Life Sciences)2020，63，11： | 8 |
| 4 | Purifi cation, characterization and hypoglycemic activity of glycoproteins obtained from pea (Pisum sativum L.)显示文摘This study aimed to isolate and characterize the structures of glycoproteins from peas and determine their hypoglycemic activity.The crude pea glycoproteins(PGP)were extracted by hot water and purified by diethylaminoethyl(DEAE)-Sepharose chromatography and Sephadex G-100 size-exclusion chromatography in sequence.Then three main fractions were obtained,namely PGP1,PGP2 and PGP3,with molecular weights of 897615,846740 and 1194692 Da,respectively.The physical and chemical properties of the three fractions were evaluated and compared by Fourier transform infrared spectroscopy(FT-IR),nuclear magnetic resonance(NMR),scanning electron microscope(SEM),high performance liquid chromatography(HPLC)and other analytical techniques.The fraction PGP2 with the highest hypoglycemic activity,was screened using the Caco-2 monolayer cell model.It can inhibit the uptake of glucose in the small intestine,as well as the activities of maltase and sucrase.After simulated gastrointestinal digestion,PGP2 signifi cantly enhanced the inhibitory effect of α-glucosidase,and slightly reduced the inhibitory ability ofα-amylase.In summary,PGP2 possessed strong hypoglycemic activity after digestion.These results indicated that PGP2 has the potential to be developed into a functional food or natural medicine for the treatment of type 2 diabetes mellitus. | Gaoyixin Qin Wu Xu Junping Liu Liyan Zhao Guitang Chen | 2021 | Food Science and Human Wellness2021，10，3： | 8 |
| 5 | Spatial and temporal distributions of nitrogen,phosphorus and heavy metals in the intertidal sediment of the Chang jiang River Estuary in China显示文摘Spatial and temporal distributions of nutrients(N and P) and heavy metals(Cu,Zn,Pb and Cd) in the intertidal sediments at Dongtan wetland of the Changjiang River(Yangtze River) Estuary were examined by laying one transect running seaward to landward during January,April,June,August and October of 2005. Total nitrogen(TN) and heavy metal concentrations in the intertidal sediment showed an increasing trend from open bare flat to the high marsh,with the maximum concentrations in the high marsh and the minimum values in open bare flat. In contrast,sediment total phosphorus(TP) concentrations changed little among sampling sites. One-way ANOVA found that there were significantly temporal variations of nutrients and heavy metals concentrations in the intertidal sediment(P <0.05) . The concentrations of heavy metals generally showed an increasing trend from January to October. As compared with other large estuaries,heavy metal contamination in the intertidal sediment of the Changjiang River Estuary was relatively low. | QUAN Weimin SHI Liyan HAN Jindi PING Xianyin SHEN Anglv CHEN Yaqu | 2010 | Acta Oceanologica Sinica2010，29，1： | 7 |
| 6 | Performance measures for management of chronic heart failure patients with acute coronary syndrome in China: results from the Bridging the Gap on Coronary Heart Disease Secondary Prevention in China (BRIG) Project显示文摘 | WANG Na ZHAO Dong LIU Jing LIU Jun Cheuk-Man Yu WANG Wei SUN Jia-yi LIYan CHEN Bu-xing | 2013 | Chinese Medical Journal2013，，14： | 7 |
| 7 | Review of CHINARE chemical oceanographic research in the Southern Ocean during 1984–2016显示文摘Between 1984 and 2016, China executed 33 Antarctic cruises with the icebreaker R/V Xuelong, which have provided opportunities for Chinese scientists to investigate the status and changes of the Southern Ocean. Research in chemical oceanography constitutes one of the primary missions of the Chinese National Antarctic Research Expedition(CHINARE). This paper reviews nearly 30 years of Chinese Antarctic expeditions, focusing on the major progress achieved in chemical oceanographic research. Specifically, the sea-surface distributions and air–sea fluxes of CO_2 and N_2O are considered, and the transport, flux, and budget of organic matter are investigated based on isotopes in the Southern Ocean, especially in Prydz Bay. In addition, the nutrient distribution and deep-water particle export in Prydz Bay and the study of aerosol heavy metal characteristics are considered. Finally, the prospects for future Chinese Antarctic chemical oceanographic research are outlined. | CHEN Liqi CHEN Min ZHAN Liyan QI Di GAO Zhongyong WANG Jianjun XU Suqing CHEN Kui ZENG Jian ZHANG Run | 2017 | Advances in Polar Science2017，28，2： | 6 |
| 8 | High-entropy rare-earth zirconate ceramics with low thermal conductivity for advanced thermal-barrier coatings显示文摘The high-entropy rare-earth zirconate((La_(0.2)Nd_(0.2)Sm_(0.2)Gd_(0.2)Yb_(0.2))_(2)Zr_(2)O_(7),5RE_(2)Zr_(2)O_(7)HEREZs)ceramics were successfully prepared by a new high-speed positive grinding strategy combined with solid-state reaction method.The microstructure,crystal structure,phase composition,and thermophysical and mechanical properties of the samples were systematically investigated through various methods.Results indicate that the samples have a single-phase defect fluorite-type crystal structure with excellent high-temperature thermal stability.The as-prepared samples also demonstrate low thermal conductivity(0.9–1.72 W·m^(−1)·K^(−1)at 273–1273 K)and high coefficient of thermal expansion(CTE,10.9×10^(−6)K^(−1)at 1273 K),as well as outstanding mechanical properties including large Young’s modulus(E=186–257 GPa)and high fracture toughness(KIC).Furthermore,the formation possibility of the as-prepared samples was verified through the first-principles calculations,which suggested the feasibility to form the 5RE_(2)Zr_(2)O_(7)HE-REZs in the thermodynamic direction.Therefore,in view of the excellent multifunctional properties exhibited by the as-prepared 5RE_(2)Zr_(2)O_(7)HE-REZs,they have great potential applications in next-generation thermal-barrier coatings(TBCs). | Debao LIU Baolu SHI Liyan GENG Yiguang WANG Baosheng XU Yanfei CHEN | 2022 | Journal of Advanced Ceramics2022，11，6： | 6 |
| 9 | Tissue engineering using 3D printed nano-bioactive glass loaded with NELL1 gene for repairing alveolar bone defects显示文摘The purposes of this study were to construct a novel tissue engineered bone composed of 3Dprinted bioactive glass block/chitosan nanoparticles(BD/CSn)composites loaded with Nel-like Type I molecular-1 DNA(pDNA-NELL1)and/or bone marrow mesenchymal stem cells(BMSCs),and study their osteogenic activities by repairing bone defects in rhesus monkeys.CSn with NELL1 gene plasmid and rhesus monkey BMSCs were composited with a BD scaffold to prepare the tissue-engineered bone.Four adult female rhesus monkeys with 10-to 12-years old and 5-7 kg in weight were used in animal experiments.The first and second premolar teeth from four regions of each monkey were removed to form bone defects with size of 10×10×5 mm,which were then implanted with above-mentioned tissue engineered bone.At 12 weeks after the implantation,gross observations,X-ray and micro-CT observations revealed that the new bone was extremely close to normal bone in mass,density,hardness,and structure.The bony cortex was smooth and closely connected to the surrounding normal bone.Histological observations revealed moderate inflammation in the repair area,and the new bone tissues were similar to normal ones.In conclusion,tissue engineered bone of this study exhibited good osteoconductivity for promoting the formation of new alveolar bone tissue,and NELL1 gene played a promotional role in bone regeneration. | Jing Zhang Yang Chen Jing Xu Jingjing Wang Chengzhang Li Liyan Wang | 2018 | Regenerative Biomaterials2018，5，4： | 6 |
| 10 | Research and development of new neodymium laser glasses显示文摘This work presents a brief introduction on three kinds of newly developed Nd^(3+)-doped laser glasses in Shanghai Institute of Optics and Fine Mechanics(SIOM), China. Two Nd^(3+)-doped phosphate glasses with lower thermal expansion coefficient and thermal shock resistance 4 times higher than that of N31 glass are developed for laser processing.Nd:Silicate and Nd:Aluminate glasses with peak emission wavelength at 1061 and 1065 nm, effective emission bandwidth of 34 and 50 nm, respectively, are developed for Exawatt-class laser system application. Fluorophosphate glasses with low nonlinear refractive index(n_2=0.6–0.86) and long fluorescence lifetime(430–510 μs) are investigated for the purpose of decreasing B integral in high-power laser system. The properties of all these glasses are presented and compared with those of commercial neodymium laser glasses. | Dongbing He Shuai Kang Liyan Zhang Lin Chen Yajun Ding Qianwen Yin Lili Hu | 2017 | High Power Laser Science and Engineering2017，5，1： | 6 |
| 11 | Fractional Envelope Analysis for Rolling Element Bearing Weak Fault Feature Extraction显示文摘The bearing weak fault feature extraction is crucial to mechanical fault diagnosis and machine condition monitoring.Envelope analysis based on Hilbert transform has been widely used in bearing fault feature extraction. A generalization of the Hilbert transform, the fractional Hilbert transform is defined in the frequency domain, it is based upon the modification of spatial filter with a fractional parameter, and it can be used to construct a new kind of fractional analytic signal. By performing spectrum analysis on the fractional envelope signal, the fractional envelope spectrum can be obtained. When weak faults occur in a bearing, some of the characteristic frequencies will clearly appear in the fractional envelope spectrum. These characteristic frequencies can be used for bearing weak fault feature extraction.The effectiveness of the proposed method is verified through simulation signal and experiment data. | Jianhong Wang Liyan Qiao Yongqiang Ye YangQuan Chen | 2017 | IEEE/CAA Journal of Automatica Sinica2017，4，2： | 5 |
| 12 | Classification and 3-D distribution of upper layer water masses in the northern South China Sea显示文摘Using the fuzzy cluster analysis and the temperature-salinity(T-S) similarity number analysis of cruise conductivity-temperature-depth(CTD) data in the upper layer(0–300 m) of the northern South China Sea(NSCS), we classify the upper layer water of the NSCS into six water masses: diluted water(D), surface water(SS),the SCS subsurface water mass(U_S), the Pacific Ocean subsurface water mass(U_P), surface-subsurface mixed water(SU) and subsurface-intermediate mixed water(UI). A new stacked stereogram is used to illustrate the water mass distribution, and to examine the source and the distribution of U_P, combining with the sea surface height data and geostrophic current field. The results show that water mass U_P exists in all four seasons with the maximum range in spring and the minimum range in summer. In spring and winter, the U_P intrudes into the Luzon Strait and the southwest of Taiwan Island via the northern Luzon Strait in the form of nonlinear Rossby eddies, and forms a high temperature and high salinity zone east of the Dongsha Islands. In summer, the U_P is sporadically distributed in the study area. In autumn, the U_P is located in the upper 200 m layer east of Hainan Island. | Jia Zhu Quanan Zheng Jianyu Hu Hongyang Lin Dewen Chen Zhaozhang Chen Zhenyu Sun Liyan Li Hao Kong | 2019 | Acta Oceanologica Sinica2019，38，4： | 5 |
| 13 | Multi-objective parameter optimization for a single-shaft series-parallel plug-in hybrid electric bus using genetic algorithm显示文摘最近,插件混合电的公共汽车(PHEB ) 的单个柄的系列平行 powertrain 为驾驶周期由于它的可改变的操作模式,优秀燃料经济和强壮的适应性成为了最流行的 powertrains 之一。为在开发阶段与单个柄的系列平行 powertrain 设置 PHEB,当选择并且匹配主要部件参数时,不过,它仍然比另外的配置面对更大的挑战。由这个问题激发了,全面多目的优化策略与典型 powertrain 为 PHEB 基于基因算法(GA ) 被开发。就公共汽车线路的重覆性和整齐而言,首先,离线的数据处理和数学统计的方法被采用,到获得一个代表性的开车周期,它能很好反映真实世界的公共汽车线路的一般特征。然后,节俭的优化目的被定义,它是由生产关键部件和精力消费的费用组成,并且与动态优化目的结合了,多客观的优化功能被提出。同时, GA 算法被用来优化参数,为新奇系列平行 powertrain 的最佳的部件联合。最后,有原型的比较被执行沿着驾驶周期验证优化 powertrain 的表演。模拟结果显示建议全面多目的优化策略获得的 powertrain 部件的参数可能得到更好的燃料经济,同时保证 PHEB 的动态性能。与原版相对照,费用在 18% 衰退了。因此,策略将为 PHEB 制造商在参数选择上提供理论指导。 | CHEN Zheng ZHOU LiYan SUN Yong MA ZiLin HAN ZongQi | 2016 | Science China(Technological Sciences)2016，59，8： | 4 |
| 14 | Role of helicity of a-helical antimicrobia peptides to improve specificity显示文摘 | Yibing Huang Liyan He Guirong Li Naicui Zhai Hongyu Jiang Yuxin Chen | 2014 | Protein & Cell2014，5，8： | 3 |
| 15 | White blood cell count and the incidence of hyperuricemia:insights from a community-based study显示文摘Hyperuricemia(HUA)is a risk factor for chronic kidney disease(CKD).The relationship between HUA and white blood cell(WBC)count remains unknown.A sampling survey for CKD was conducted in Sanlin community in 2012 and 2014.CKD was defined as proteinuria in at least the microalbuminuric stage or an estimated GFR of 60 mL/(min·1.73 m2).HUA was defined as serum uric acid>420µmol/L in men and>360µmol/L in women.This study included 1024 participants.The prevalence of HUA was 17.77%.Patients with HUA were more likely to have higher levels of WBC count,which was positively associated with HUA prevalence.This association was also observed in participants without CKD,diabetes mellitus,hyperlipidemia,or obesity.Multivariate logistic regression analysis showed that WBC count was independently associated with the risk for HUA in male and female participants.Compared with participants without HUA,inflammatory factors such as high-sensitivity C-reactive protein,tumor necrosis factor-α,and interleukin 6 increased in participants with HUA.Hence,WBC count is positively associated with HUA,and this association is independent of conventional risk factors for CKD. | Jian Liu Pingyan Shen Xiaobo Ma Xialian Yu Liyan Ni Xu Hao Weiming Wang Nan Chen | 2019 | Frontiers of Medicine2019，13，6： | 3 |
| 16 | Phase Ⅲ Clinical Trials of the Cell Differentiation Agent-2 (CDA-2): Therapeutic Efficacy on Breast Cancer, Non-Small Cell Lung Cancer and Primary Hepatoma显示文摘 | Fengyi Feng Qing Lu Changquan Ling Yang Zhang Fengzhan Qin Huaqing Wang Wenxia Huang Shunchang Jiao Qiang Chen Mingzhong Li Yunzhong Zhu Meizhen Zhou Jun Ren Yetao Gao Jingpo Zhao Rongsheng Zheng Wenhua Zhao Zhiqiang Meng Fang Li Qizhong Zhang Dongli Zhao Liyan Xu Yongqiang Zhang Yanjun Zhang Zhenjiu Wang Shuonqi Liu Ming C. Liau | 2005 | Chinese Journal of Clinical Oncology2005，2，4： | 3 |
| 17 | Discovery of a high-altitude ecotype and ancient lineage of Arabidopsis thaliana from Tibet显示文摘Arabidopsis thaliana(A.thaliana)has long been a model species for dicotyledon study,and was the first flowering plant to get its genome completed sequenced[1].Although most wild A.thaliana are collected in Europe,several studies have found a rapid A.thaliana west-east expansion from Central Asia[2].The Qinghai-Tibet Plateau(QTP)is close to Central Asia and known for its high alti- | Liyan Zeng Zhuoya Gu Min Xu Ning Zhao Weidong Zhu Takahiro Yonezawa Tianmeng Liu Lha Qiong Tashi Tersing Lingli Xu Yang Zhang Rongyan Xu Ningyu Sun Yanyan Huang Jiankun Lei Liang Zhang Feng Xie Fang Zhang Hongya Gu Yupeng Geng Masami Hasegawa Ziheng Yang M. James C. Crabbe Fan Chen Yang Zhong | 2017 | Science Bulletin2017，62，24： | 3 |
| 18 | Change of Ecological Footprint and Analysis of Ecological Sustainability——Taking Zhangjiakou City as an Example显示文摘This paper researches the ecological sustainability of Zhangjiakou City, Hebei Province, China, using the ecological footprint model. According to the study we find that Zhangjiakou City was in the situation of ecological deficit from 1990 to 2000 and the deficit had the enlarging tendency. In 1990 the per capita ecological footprint was 0.964 and the per capita ecological capacity was 0.518, thus it can be calculated that the per capita ecological deficit was –0.446. However in 2000, the per capita ecological footprint increased to 1.068, at the same time the per capita eco- logical capacity decreased to 0.471, then the per capita ecological deficit in 2000 was –0.597. Furthermore, this paper studies the ecological sustainability of the city from the changes of the ecological footprint of per 10,000 yuan GDP and the productivity of ecological system. Finally the authors point out the shortage of the model and the way to improve it. | WANG Liyan LIU Yi CHEN Tian | 2007 | Chinese Geographical Science2007，17，1： | 2 |
| 19 | N,P-codoped porous carbon derived from chitosan with hierarchical N-enriched structure and ultra-high specific surface Area toward high-performance supercapacitors显示文摘In this work,a facile'carbonization-activation'strategy is developed to synthesize N,P-codoped hierarchical porous carbon.Phosphoric acid is innovatively introduced during the hydrothermal process to achieve in-situ P doping as well as create abundant pores,and the employment of sodamide is of vital importance to simultaneously serve as activating agent and N-source to succeed a high-level N doping.Thus,the obtained samples exhibit a unique three-dimensional hierarchical structure with an ultra-high specific surface area(3646 m^(2)g^(-1))and ultra-high N-doping level(9.81 at.%).Computational analyses confirm that N,P co-doping and higher N content can enhance active sites and widen potential differences of carbon materials to improve their capacitance.The as-prepared carbon materials demonstrate superior electrochemical performances,such as an ultra-high capacitance of 586 Fg^(-1)at 1 Ag^(-1),a superior rate capability of 409 Fg^(-1)at 20 Ag^(-1),and excellent long-term stability of 97%capacitance retention after10,000 cycles in 6 M KOH.Moreover,an assembled symmetric supercapacitor delivers a high energy density of 28.1 Wh kg^(-1)at the power density of 450 W kg^(-1)in 1 M Na_(2)SO_(4),demonstrating a great potential for applications in supercapacitors. | Xipeng Xin Na Song Ruiming Jia Bingnan Wang Hongzhou Dong Shuai Ma Lina Sui Yingjie Chen Qian Zhang Lifeng Dong Liyan Yu | 2021 | Journal of Materials Science & Technology2021，，29： | 2 |
| 20 | Self-assembled honokiol-loaded micelles based on poly(?-caprolactone)-poly(ethylene glycol)-poly(?-caprolactone) copolymer显示文摘 | XiaWei Wei ChangYang Gong Shuai Shi ShaoZhi Fu Ke Men Shi Zeng XiuLing Zheng MaLing Gou LiJuan Chen LiYan Qiu ZhiYong Qian | 2008 | International Journal of Pharmaceutics2008，，1： | 1 |
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