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| 1 | Impact of diabetes mellitus on risk of cardiovascular disease and all-cause mortality: Evidence on health outcomes and antidiabetic treatment in United States adults显示文摘AIMTo examine the epidemic of diabetes mellitus (DM) and its impact on mortality from all-cause and cardiovascular disease (CVD), and to test the effect of antidiabetic therapy on the mortality in United States adults. METHODS The analysis included a randomized population sample of 272149 subjects ages ≥ 18 years who participated in the National Health Interview Surveys (NHIS) in2000-2009. Chronic conditions (hypertension, DM and CVD) were classified by participants’ self-reports of physician diagnosis. NHIS-Mortality Linked Files, and NHIS-Medical Expenditure Panel Survey Linkage Fileson prescribed medicines for patients with DM were used to test the research questions. χ 2, Poisson and Cox’s regression models were applied in data analysis.RESULTS Of all participants, 22305 (8.2%) had DM. The prevalence of DM significantly increased from 2000 to 2009 in all age groups (P < 0.001). Within an average 7.39 (SD= 3) years of follow-up, male DM patients had 1.56 times higher risk of death from all-cause (HR = 1.56, 95%CI:1.49-1.64), 1.72 times higher from heart disease [1.72 (1.53-1.93)], 1.48 times higher from cerebrovascular disease [1.48 (1.18-1.85)], and 1.67 times higher from CVD [1.67 (1.51-1.86)] than subjects without DM,respectively. Similar results were observed in females. In males, 10% of DM patients did not use any antidiabetic medications, 38.1% used antidiabetic monotherapy, and 51.9% used ≥ 2 antidiabetic medications. These corresponding values were 10.3%, 40.4% and 49.4% in females. A significant protective effect of metformin monotherapy or combination therapy (except for insulin) on all-cause mortality and a protective but non-significant effect on CVD mortality were observed. CONCLUSION This is the first study using data from multiple linkage files to confirm a significant increased prevalence of DM in the last decade in the United States. Patients with DM have significantly higher risk of death from all-cause and CVD than those without DM. Antidiabetic mediations,specifically for metformin use, show a protective effect against all-cause and CVD mortalities. | Longjian Liu Barbara Simon Jinggaofu Shi Arshpreet Kaur Mallhi Howard J Eisen | 2016 | World Journal of Diabetes2016，7，18： | 12 |
| 2 | Potassium 2-(l-hydroxypentyl)-benzoate attenuates neuroinflammatory responses and upregulates heme oxygenase-1 in systemic lipopolysaccharide-induced inflammation in mice显示文摘A neuroinflammatory response is commonly involved in the progression of many neurodegenerative diseases. Potassium 2-(1-hydroxypentyl)-benzoate(PHPB), a novel neuroprotective compound, has shown promising effects in the treatment of ischemic stroke and Alzheimer's disease(AD). In the present study, the anti-inflammatory effects of PHPB were investigated in the plasma and brain of C57BL/6 mice administered a single intraperitoneal(i.p.) injection of lipopolysaccharide(LPS). Levels of i NOS and the cytokines TNFα, IL-1β and IL-10 were elevated in plasma, cerebral cortex and hippocampus after LPS injection and the number of microglia and astrocytes in cortex and hippocampus were increased. LPS also upregulated the expression of heme oxygenase-1(HO-1) in the cortex and hippocampus. PHPB reduced the levels of i NOS and cytokines in the plasma and brain, decreased the number of microglia and astrocytes and further enhanced the upregulation of HO-1. In addition, PHPB inhibited the LPS-induced phosphorylation of ERK, P38 and JNK. These results suggest that PHPB is a potential candidate in the treatment of neurodegenerative diseases through inhibiting neuroinflammation. | Chunyang Zhao Weizhen Hou Hui Lei Longjian Huang Shan Wang Dandan Cui Changhong Xing Xiaoliang Wang Ying Peng | 2017 | Acta Pharmaceutica Sinica B2017，7，4： | 9 |
| 3 | Simulation of phase transition process using lattice Boltzmann method显示文摘A new lattice Boltzmann model based on SC model, is proposed to describe the liquid-vapor phase transitions. The new model is validated through the simulation of the one-component phase transition process. Compared with the simulation results of van der Waals gas and the Maxwell equal-area construction, the results of the new model have a better agreement with the analytical solutions than those of SC and Zhang models. Since the obtained temperature range and the maximum density ratio in this model are expanded, and the magnitude of maximum spurious current is only between those of SC and Zhang models, it is believed that this new model has better stability than SC and Zhang models. Consequently, the application scope of this new model is expanded compared with the existing phase transition models. According to the principle of the corresponding states in engineering thermodynamics, the simulations of ammonia and water phase transition process were implemented using this new model with different equations of state. Compared with the experimental data of ammonia and water, the results show that the Peng-Robinson is the best equation of state to describe the phase transition process of ammonia and water. Especially, the simulation results of ammonia with Peng-Robinson equation of state have an excellent agreement with its experimental data. Therefore these simulation results have a significant influence on the real engineering applications. | ZENG JianBang LI LongJian LIAO Quan CUI WenZhi CHEN QingHua PAN LiangMing | 2009 | Chinese Science Bulletin2009，54，24： | 8 |
| 4 | Bph30confers resistance to brown planthopperby fortifying sclerenchyma in rice leaf sheaths显示文摘Phloem-feeding insects cause massive losses in agriculture and horticulture.Host plant resistance to phloem-feeding insects is often mediated by changes in phloem composition,which deter insect settling and feeding and decrease viability.Here,we report that rice plant resistance to the phloem-feeding brown planthopper(BPH)is associated with fortification of the sclerenchyma tissue,which is located just beneath the epidermis and a cell layer or two away from the vascular bundle in the rice leaf sheath.We found that BPHs prefer to feed on the smooth and soft region on the surface of rice leaf sheaths called the long-cell block.We identified Bph30 as a rice BPH resistance gene that prevents BPH stylets from reaching the phloem due to the fortified sclerenchyma.Bph30 is strongly expressed in sclerenchyma cells and enhances cellulose and hemicellulose synthesis,making the cell walls stiffer and sclerenchyma thicker.The structurally fortified sclerenchyma is a formidable barrier preventing BPH stylets from penetrating the leaf sheath tissues and arriving at the phloem to feed.Bph30 belongs to a novel gene family,encoding a protein with two leucine-rich domains.Another member of the family,Bph40,also conferred resistance to BPH.Collectively,the fortified sclerenchyma-mediated resistance mechanism revealed in this study expands our understanding of plant-insect interactions and opens a new path for controlling planthoppers in rice. | Shaojie Shi Huiying Wang Lingyun Nie Di Tan Cong Zhou Qian Zhang YiLi Bo Du Jianping Guo Jin Huang DiWu Xiaohong Zheng Wei Guan Junhan Shan Lili Zhu Rongzhi Chen Longjian Xue Linda L.Walling Guangcun He | 2021 | Molecular Plant2021，14，10： | 7 |
| 5 | Optimal scheduling strategy for virtual power plants based on credibility theory显示文摘The virtual power plant(VPP)is a new and efficient solution to manage the integration of distributed energy resources(DERs)into the power system.Considering the unpredictable output of stochastic DERs,conventional scheduling strategies always set plenty of reserve aside in order to guarantee the reliability of operation,which is too conservative to gain more benefits.Thus,it is significant to research the scheduling strategies of VPPs,which can coordinate the risks and benefits of VPP operation.This paper presents a fuzzy chance-constrained scheduling model which utilizes fuzzy variables to describe uncertain features of distributed generators(DGs).Based on credibility theory,the concept of the confidence level is introduced to quantify the feasibility of the conditions,which reflects the risk tolerance of VPP operation.By transforming the fuzzy chance constraints into their equivalent forms,traditional optimization algorithms can be used to solve the optimal scheduling problem.An IEEE 6-node system is employed to prove the feasibility of the proposed scheduling model.Case studies demonstrate that the fuzzy chance strategy is superior to conservative scheduling strategies in realizing the right balance between risks and benefits. | Qian Ai Songli Fan Longjian Piao | 2016 | Protection and Control of Modern Power Systems2016，1，1： | 3 |
| 6 | Structural characterisation of polysaccharides from Tricholoma matsutake and their antioxidant and antitumour activities显示文摘 | Lijun You Qing Gao Mengying Feng Bao Yang Jiaoyan Ren Longjian Gu Chun Cui Mouming Zhao | 2013 | Food Chemistry2013，，4： | 2 |
| 7 | The non-halogen flame retardant epoxy resin based on a novel compound with phosphaphenanthrene and cyclotriphosphazene double functional groups显示文摘 | Qian Lijun Ye Longjian Xu Guozhi | 2011 | Polym Degrad Stab2011，96，6： | 1 |
| 8 | Renewable energy from agro-residues in China: solid biofuels and biomass briquetting technology显示文摘 | Chen Longjian Xing Li Han Lujia | 2009 | Renewable and Sustainable Energy Reviews2009，13，12： | 1 |
| 9 | A rapid and accu- rate method for on-line measurement ofstraw-coal blends using near infrared spectroscopy 显示文摘 | He Cheng Chen Longjian Yang Zengling | 2012 | Bioresource Technology2012，110，4： | 1 |
| 10 | The development of agro-residue densified fuel in China based on energetics analysis 显示文摘 | Chen Longjian Xing Li Han Lujia | 2010 | Waste Management2010，30，5： | 1 |
| 11 | Thermal degradation behavior of the compound containing phosphaphenanthrene and phosphazene groups and its flame retardant mechanism on epoxy resin显示文摘 | Lijun Qian Longjian Ye Yong Qiu Shuren Qu | 2011 | Polymer2011，，24： | 1 |
| 12 | in vitro Antioxidant activity of protein hydrolysates prepared from corn gluten meal显示文摘 | LI Xiuxia HAN Lujia CHEN Longjian | 2008 | Journal of the Science of Food and Agriculture2008，88，9： | 1 |
| 13 | Renewable energy from agro-residues in China: Solid biofuels and biomass briquet- ting technology 显示文摘 | Longjian Chen Li Xing Lujia Han | 2009 | Renewable and Sustainable Energy Re-views2009，13，： | 1 |
| 14 | Numeri- cal investigations on cold gas dynamic spray process with nano and microsize particles显示文摘 | Jen Tien Chien Li Longjian Cui Wenzhi | 2005 | International Journal of Heat and Mass Transfer2005，48，： | 1 |
| 15 | 显示文摘 | Qian Lijun Ye Longjian Xu Guozhi | 2011 | Polymer Degra- dation and Stability2011，96，6： | 1 |
| 16 | A rapid and accurate method for on-line measurement of straw-coal blends using near infrared spectroscopy显示文摘 | He cheng Chen Longjian Yang Zengling | 2012 | Bioresource Technology2012，，4： | 1 |
| 17 | In vitro antioxidant activity of protein hydrolysates prepared from com glutenmeal显示文摘 | LI Xiuxia HAN Lujia CHEN Longjian | 2008 | Journal of the Science Food and Agriculture2008，88，9： | 1 |
| 18 | Pomelo Peel-Inspired 3D-Printed Porous Structure for Efficient Absorption of Compressive Strain Energy显示文摘The porous structure in pomelo peel is believed to be responsible for the protection of its fruit from damage during the free falling from a tree.The quantitative understanding of the relationship between the deformation behavior and the porous structure could pave the way for the design of porous structures for efficient energy absorption.Here,a universal feature of pore distribution in pomelo peels along the radial direction is extracted from three varieties of pomelos,which shows strong correlation to the deformation behavior of the peels under compression.Guided by the porous design found in pomelo peels,porous polyether-ether-ketone(PEEK)cube is additively manufactured and possesses the highest ability to absorb energy during compression as compared to the non-pomelo-inspired geometries,which is further confirmed by the finite element simulation.The nature-optimized porous structure revealed here could guide the design of lightweight and high-energy-dissipating materials/devices. | Baisong Yang Wenhui Chen Renlong Xin Xiaohong Zhou Di Tan Chuan Ding You Wu Liang Yin Chuyang Chen Shan Wang Zhenglei Yu Jonathan TPham Sheng Liu Yifeng Lei Longjian Xue | 2022 | Journal of Bionic Engineering2022，19，2： | 1 |
| 19 | in vitro Antioxidant activity of protein hydrolysates prepared from corn gluten meal显示文摘 | LI Xiuxia RAN Lajia CHEN Longjian | 2008 | Journal of the Science of Food and Agriculture2008，88，9： | 1 |
| 20 | Grey Rela- tion Analysis of Lignocellulose Composition显示文摘 | Guangqun Huang Na Liao Longjian Chen | 2011 | Materials for Renewable Energy & Environment2011，，1： | 1 |
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