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| 1 | Exercise as a prescription for patients with various diseases显示文摘A growing understanding of the benefits of exercise over the past few decades has prompted researchers to take an interest in the possibilities of exercise therapy.Because each sport has its own set of characteristics and physiological complications that tend to occur during exercise training,the effects and underlying mechanisms of exercise remain unclear.Thus,the first step in probing the effects of exercise on different diseases is the selection of an optimal exercise protocol.This review summarizes the latest exercise prescription treatments for 26 different diseases:musculoskeletal system diseases(low back pain,tendon injury,osteoporosis,osteoarthritis,and hip fracture),metabolic system diseases(obesity,type 2 diabetes,type 1 diabetes,and nonalcoholic fatty liver disease),cardio-cerebral vascular system diseases(coronary artery disease,stroke,and chronic heart failure),nervous system diseases(Parkinson’s disease,Huntington’s disease,Alzheimer’s disease,depression,and anxiety disorders),respiratory system diseases(chronic obstructive pulmonary disease,interstitial lung disease,and after lung transplantation),urinary system diseases(chronic kidney disease and after kidney transplantation),and cancers(breast cancer,colon cancer,prostate cancer,and lung cancer).Each exercise prescription is displayed in a corresponding table.The recommended type,intensity,and frequency of exercise prescriptions are summarized,and the effects of exercise therapy on the prevention and rehabilitation of different diseases are discussed. | Xin Luan Xiangyang Tian Haixin Zhang Rui Huang Na Li Peijie Chen Ru Wang | 2019 | Journal of Sport and Health Science2019，8，5： | 61 |
| 2 | Adsorption removal of phosphate from aqueous solution by active red mud显示文摘红泥是氧化铝工业的浪费并且有是为阴离子污染物质的吸附的活跃部件的高 TiO2 和 Fe2O3 内容。在这研究,由热处理和酸热的处理激活的红泥的磷酸盐的举起是影响吸附的 investigated.Thefactors 也被调查。结果证明红泥样品与 0.25 mol/L HCl 在 80 ℃用酸热的方法对待因为 2 h 完成了最高的 phosphateremoval.For 激活热的红泥,更好为 2 h preformed 在 700 ℃加热的样品人另外的热处理。由激活的红泥的磷酸盐移动是显著地 pH 依赖者, 7 是的 andpH 为磷酸盐移动的最佳的 pH。吸附适合好的兰米尔等温线模型和酸热的激活的红泥的最大的吸附能力,激活的热取样分别地是 202.9 mgP/g 和 155.2 mgP/g。 | LIU Chang-jun LI Yan-zhong LUAN Zhao-kun CHEN Zhao-yang ZHANG Zhong-guo JIA Zhi-ping | 2007 | Journal of Environmental Sciences2007，19，10： | 47 |
| 3 | Chinese Multidisciplinary Expert Consensus on the Diagnosis and Treatment of Hyperuricemia and Related Diseases显示文摘 | Zou, He-Jian Wu, Hu-Sheng Zhou, Jing-Guo Zeng, Xue-Jun Dai, Lie Wu, Hua-Xiang Zhu, Xiao-Xia Mei, Chang-Lin Hao, Chuan-Ming Chen, Nan Liu, Bi-Cheng Chen, Jiang-Hua Yang, Li Nie, Jing Yu, Chen Peng, Ai Yu, Sheng-Qiang Li, Lin Ge, Jun-Bo Huo, Yong Zhang, Shu-Yang Chen, Yun-Dai Dong, Yu-Gang Liang, Chun Dai, Yu-Xiang Gao, Xin Li, Chang-Gui Zhao, Jia-Jun Chen, Hai-Bing Cheng, Zhi-Feng Lin, Huan-Dong Guan, Yang-Tai Wang, Kai Luo, Ben-Yan Dai, Ruo-Lian Jiang, Quan Xue, Luan Liang, Chao-Chao Chen, Ming Fan, Song | 2017 | Chinese Medical Journal2017，，20： | 30 |
| 4 | Tonoplast calcium sensors CBL2 and CBL3 control plant growth and ion homeostasis through regulating V-ATPase activity in Arabidopsis显示文摘对发展、环境的暗示的植物回答被钙经常调停(被多样的钙传感器播送的 Ca 2+) 信号。calcineurin 象 B 一样(CBL ) 蛋白质家庭代表通过和一组交往 CBL 蛋白质 kinases 的特定的相互作用译码钙信号的钙传感器。我们报导 Arabidopsis CBL2 和 CBL3 的功能的分析,对通过 N 终端指向 tonoplast 的 vacuolar 膜局部性的二个密切相关的 CBL 成员定序。当 cbl2 或 cbl3 单身者异种没从野类型显示出任何 phenotypic 差别时, cbl2 cbl3 两倍异种与叶尖端坏死,不发达的根,更短的 siliques 和更少种子被阻碍。这些缺点在 vha-a2 vha-a3 使人想起那些在 vacuolar H +-ATPase (V-ATPase ) 缺乏的两倍异种。确实, V-ATPase 活动在 cbl2 cbl3 被减少两倍变异的、连接 tonoplast CBL 类型钙传感器到 V-ATPase 的规定。而且, cbl2 cbl3 两倍异种在离子的忍耐和微量元素累积被损害,与在被显示了在离子区分工作的 V-ATPase 活动的缺点一致。我们的结果建议钙传感器 CBL2 和 CBL3 用作在钙发信号和 V-ATPase 之间的分子的连接,细胞内部的离子动态平衡的一个中央管理者。 | Ren-Jie Tang Hua Liu Yang Yang Lei Yang Xiao-Shu Gao Veder J Garcia Sheng Luan Hong-Xia Zhang | 2012 | Cell Research2012，22，12： | 26 |
| 5 | A DTX/MATE-Type Transporter Facilitates Abscisic Acid Efflux and Modulates ABA Sensitivity and Drought Tolerance in Arabidopsis显示文摘Abscisic 酸(骆驼毛的织物) 在植物调整众多的生理、发展的过程。最近的研究识别 intracellularABA 受体,含有越过为骆驼毛的织物察觉到和反应同样关键的房间膜的骆驼毛的织物的运输。这里,我们 reportthat DTX/Multidrug 和有毒的复合挤出(配偶) 在 Arabidopsis thaliana 的家庭成员, AtDTX50,作为骆驼毛的织物流出 transporter 工作。当在 Escherichia coli 紧张和 Xenopus 卵母细胞房间 heterologously 表示了时, AtDTX50 被发现便于骆驼毛的织物流出。而且,与骆驼毛的织物预装的 dtx50 异种叶肉房间释放了更少的骆驼毛的织物与相比野类型(WT ) 。AtDTX50 基因主要在脉管的纸巾和警卫房间被表示,它的表示由 exogenousABA 是强烈起来调整的。AtDTX50::GFP 熔化蛋白质对血浆膜主要局部性。dtx50 异种植物被观察对在生长抑制的骆驼毛的织物更敏感。另外与 WT 相比, dtx50 异种植物对有更低的有气孔的传导力的干旱更容忍,与它是的功能一致在警卫房间的骆驼毛的织物 effluxcarrier。 | Haiwen Zhang Huifen Zhu Yajun Pan Yuexuan Yu Sheng Luan Legong Li | 2014 | Molecular Plant2014，7，10： | 23 |
| 6 | Blockade of Tim-3 Pathway Ameliorates Interferon-γ Production from Hepatic CD8^+ T Cells in a Mouse Model of Hepatitis B Virus Infection显示文摘T cell immunoglobulin-and mucin-domain-containing molecule-3(Tim-3) has been reported to participate in the pathogenesis of inflammatory diseases. However,whether Tim-3 is involved in hepatitis B virus(HBV) infection remains unknown. Here,we studied the expression and function of Tim-3 in a hydrodynamics-based mouse model of HBV infection. A significant increase of Tim-3 expression on hepatic T lymphocytes,especially on CD8+ T cells,was demonstrated in HBV model mice from day 7 to day 18. After Tim-3 knockdown by specific shRNAs,significantly increased IFN-γ production from hepatic CD8+ T cells in HBV model mice was observed. Very interestingly,we found Tim-3 expression on CD8+ T cells was higher in HBV model mice with higher serum anti-HBs production. Moreover,Tim-3 knockdown influenced anti-HBs production in vivo. Collectively,our data suggested that Tim-3 might act as a potent regulator of antiviral T-cell responses in HBV infection. | Ying Ju Nan Hou Xiaoning Zhang Di Zhao Ying Liu Jinjin Wang Fang Luan Wei Shi Faliang Zhu Wensheng Sun Lining Zhang Chengjiang Gao Lifen Gao Xiaohong Liang Chunhong Ma | 2009 | Cellular & Molecular Immunology2009，6，1： | 19 |
| 7 | Percutaneous coronary intervention for chronic total occlusion in 1263 patients:a single-center report显示文摘背景冠的长期的全部的吸藏(CTO ) 在 interventional 心病学仍然是最挑战性的损害子集之一,甚至与医药设备和操作符专家知识的开发。这研究被进行检验在损害特征和程序的成功和在里面医院的发生之间的关系在为在沈阳经历了在1995年6月和2005年12月之间的一种总线标准的有 CTO 的 1263 个病人的 CTO.Methods 临床、冠的 angiographic 数据的经皮的冠的干预(一种总线标准)以后的主要不利心脏的事件(向) PLA 的医院将军是回顾地在那里的 analyzed.Results 是与吝啬的吸藏 tim 位于 1596 个容器的 1625 CTO 损害1647 冠的 stents 的一个总数被植入到目标损害。全面病人和损害成功率分别地是 90.8 %(1147/1263 ) 和 88.9 %(1445/1625 ) 。一种总线标准的成功率与吸藏的长持续时间被拒绝,突然的错过树桩,衔接担保在堵塞长度的 15 公里,对严重石灰化或扭曲和 ostial 或 CTO 损害(P 0.05 ) 的远侧的地点中等。程序的失败发生在 116 个病人,由指南电线(81.0%) 或汽球(19.0%) 的不可能引起了通过 occlusion.There 不在过程期间是死亡,但是 2 个病人患了尖锐 stent 血栓,另外的 9 个病人有尖锐或迟了的心囊的穿孔。那些复杂并发症都成功地被对待。在过程以后, 3patients 死了,因为稍尖的 stent 血栓和 1underwent, 4 经历了迫切目标容器 revascularization 冠在在里面医院期间由于冠的管绕过接枝外科时期。全面在里面医院向率是 0.6%(8/1263 ) 。没有在里面医院 MACE.Conclusions, Drug-eluting stents 在一个富有经验的心中心在 198 个病人被使用,与冠的 CTO 损害为病人获得一种总线标准和有利临床的结果的相对高的成功率是可能的。 | HAN Ya-ling WANG Shou-li JING Quan-min LI Yi ZHANG Jian MA Ying-yan LUAN Bo | 2006 | Chinese Medical Journal2006，，14： | 18 |
| 8 | Molecular epidemic survey on co-prevalence of scrub typhus and marine typhus in Yuxi city,Yunnan province of China显示文摘背景人的 rickettsioses 是世界范围的动物病,因为他们的不正常的表明,把他们区分开来与另外的传染疾病不是容易的。在最近的年里有从 Hongta 区域 CDC 的未知原因的发烧的病人的数字,云南省的 Yuxi 城市在夏天显著地一直在增加。诊断擦洗斑诊伤寒被本地临床医生做。以便查明疾病,我们从 8 月 18 日为如此的病人带了实验室调查去 26, 2005 .Methods 活跃监视从 2002 ~ 2004 由云南省的 Hongta 区域 CDC Yuxi 城市被进行,基本数据从根据临床的定义证实的盒子被获得。平均发生和镇级的发生在学习时期期间被计算。血样品被 PCR 和血清学的测试分析。把一个配对的将军基于 groEL 基因序列指向斑诊伤寒的外部教材( Gro-1 和 Gro-2 ),看到的发烧象一样擦洗斑诊伤寒和二份配对的内部教材( SF1 , SR2 和 TF1 , TR2 )为和看到的发烧的斑诊伤寒并且分别地,擦洗斑诊伤寒被设计执行复合巢的 PCR 。血清学的试金被间接 immunofluorescence 试金与 7 不同立克次氏体属微生的抗原执行,即, R。mossori, R。sibirica, R。conorii, O。tsutsugamushi, B。quintana, B。henselae 和 Coxilella burnetii 阶段 Ag.Results 流行病学的监视从 2002 ~ 2004 显示出那, scrub 斑诊伤寒的平均发生或与鼠科的斑诊伤寒擦洗斑诊伤寒分别地是 222.1/105, 204.3/105 和 109.6/105。在病的尖锐舞台期间拿的 13 件血样品, 6 显示出放大产品为擦洗斑诊伤寒和百分之百显示出的定序的产品, 99% , 99% , 99% , 99% , 99% 类似到 O。tsutsugamushi Karp 而是他们分享了一样的推出的氨基酸序列,它与 O 的热吃惊蛋白质显示了 100% 身份。tsutsugamushi Karp 紧张。百分之百,为鼠科的斑诊伤寒和他们的相应核苷酸序列的五个产出的 PCR 产品展出了 100%99% , 99% 和 99% 类似到 R。mossori Wilmington 和预言的氨基酸序列的分析显示了 100% , 100%,98% ,有 R 的热吃惊蛋白质的 98% 和 98% 身份。mossoriWilmington 紧张。8 个 PCR 积极病人, 3 显示出合作感染与鼠科的斑诊伤寒擦洗斑诊伤寒。从热性的病人的所有 13 件浆液样品对 O 是积极的。tsutsugamushi 并且他们中的 8 个对 R 是积极的。mossori。所有对 O 8 个配对的标本有抗体的四折的举起。为斑诊伤寒的 tsutsugamushi,和 seroconversion 在 3 件配对的浆液样品被表明。另一在学习发现是 Q 发烧的高 seropositive 流行(76.9%) 是它证实了的 detected.Conclusion 那合作流行与鼠科的斑诊伤寒擦洗斑诊伤寒正在发生在云南省的 Yuxi 城市里,中国。另外的立克次氏体属微生的疾病也需要在这些区域被调查。 | ZHANG Li-juan LI Xue-mei ZHANG De-rong ZHANG Jing-shan DI Ying LUAN Ming-chun FU Xiu-ping | 2007 | Chinese Medical Journal2007，，15： | 18 |
| 9 | COVID-19 Outbreak Caused by Contaminated Packaging of Imported Cold-Chain Products—Liaoning Province,China,July 2020显示文摘Summary What is known about this topic?Few major outbreaks of coronavirus disease 2019(COVID-19)have occurred in China after major nonpharmaceutical interventions and vaccines have been deployed and implemented.However,sporadic outbreaks that had high possibility to be linked to cold chain products were reported in several cities of China..What is added by this report?In July 2020,a COVID-19 outbreak occurred in Dalian,China.The investigations of this outbreak strongly suggested that the infection source was from COVID-19 virus-contaminated packaging of frozen seafood during inbound unloading personnel contact.What are the implications for public health practice?Virus contaminated paper surfaces could maintain infectivity for at least 17–24 days at-25℃.Exposure to COVID-19 virus-contaminated surfaces is a potential route for introducing the virus to a susceptible population.Countries with no domestic transmission of COVID-19 should consider introducing prevention strategies for both inbound travellers and imported goods.Several measures to prevent the introduction of the virus via cold-chain goods can be implemented. | Huilai Ma1 Jianqun Zhang Ji Wang Ying Qin Cao Chen Yang Song Liang Wang Jun Meng Lingling Mao Fengqin Li Ning Li Jian Cai Yong Zhang Dayan Wang Yunting Xia Hong Wang Shaofeng Jiang Xiang Zhao Peihua Niu Wenjie Tan Tao Ma Yecheng Yao Naiying Mao Zhen Zhu Tianjiao Ji Qian Yang Baoying Huang Li Zhao Jianxing Yu Li Bai Shuangli Zhu Dongyan Wang Yan Zhang Yingwei Sun Mingchun Luan Yanhai Wang Haibo Sun Shihong Yang Zhijian Bo Xiang Ren Zhongjie Li George Fu Gao Wei Yao Wenqing Yao Zijian Feng Wenbo Xu | 2021 | China CDC weekly2021，3，21： | 16 |
| 10 | Estimation of genetic parameters and breeding values in shrimp F enneropenaeus chinensis using the REML/BLUP procedure显示文摘An analysis of a selection experiment was used to assess the impact of various animal model structures on REML estimates of variance components.The analyses were carried out based on 162 d body mass (BM) of 1 287 animals from 21 paternal half-sib groups of Fenneropenaeus chinensis.Estimated breeding values (EBV) of BM of all individuals were estimated using eight statistical models (A,AB,ABC,ABDC,ABMFC,ABMDC,ABFDC and ABMFDC) and BLUP (best linear unbiased prediction).These models were designed involving factors such as sex,spawn date as fixed effects,maternal genetic effects,full-sib family effects as random effects,mean BM of families at tagging and age at recording (covariate).The results demonstrate the importance of correct interpretation of effects in the data set,particularly those that can influence resemblance between relatives.The data structure and the particular model that was applied markedly influenced the magnitude of variance component estimates.Models based on few effects obtained upward biased estimates of additive genetic variance.The accuracy of genetic parameters and breeding value estimated by ABFDC model was higher than other models.The results imply that additive genetic direct value,full-sib family effects,and covariance effects besides sex and spawn date as fixed effects were very important for estimating genetic parameters and breeding value of body mass.This model had a heritability estimate of 162 d BM of 0.44.The comparison of the efficiency of selection based on breeding values or phenotypic value revealed great difference:average breeding value of the best 24 families selected by the 162 d BM breeding value and phenotype were 0.577 g and 0.366 g,respectively,representing a 36.57% higher efficiency in the former.In conclusion,selection based on breeding value was more effective than selection based on phenotypic value.Our results indicate that effects influencing the magnitude of estimates should be taken into account when estimating heritability and breeding values for BM. | ZHANG Tianshi KONG Jie LUAN Sheng WANG Qingyin LUO Kun TIAN Yia | 2011 | Acta Oceanologica Sinica2011，30，1： | 12 |
| 11 | Design and development of an oral remdesivir derivative W116 against SARS-CoV-2显示文摘Dear Editor,Since the declaration of COVID-19 as a global pandemic on March 11,2020,this pandemic has been circulating for 17 months throughout the world,leading to more than 200 million infections and nearly 4.4 million deaths as of August 15,2021.The pathogen of COVID-19 is a novel coronavirus named SARS-CoV-2,which shares-79%genome sequence identity with SARS-CoV.1 At the early stage of the COVID-19 outbreak,5ARS-CoV-2 caused great panic in the hardest-hit areas due to its high transmissibility and pathogenicity.To fight the COVID-19 crisis,drug repurposing was immediately pursued in order to find potential therapeutics. | Yuanchao Xie Wanchao Yin Yumin Zhang Weijuan Shang Zhen Wang Xiaodong Luan Guanghui Tian Haji A.Aisa Yechun Xu Gengfu Xiao Jia Li Hualiang Jiang Shuyang Zhanq Leike Zhang H.Eric Xu Jingshan Shen | 2021 | Cell Research2021，31，11： | 12 |
| 12 | Inhibition of autophagy induced by proteasome inhibition increases cell death in human SHG-44 glioma cells显示文摘 | Peng-fei GE Ji-zhou ZHANG Xiao-fei WANG Fan-kai MENG Wen-chen LI Yong-xin LUAN Feng LING Yi-nan LUO | 2009 | Acta Pharmacologica Sinica2009，30，7： | 11 |
| 13 | FLOW RESISTANCE AND HEAT TRANSFER CHARACTERISTICS OF A NEW-TYPE PLATE HEAT EXCHANGER显示文摘A new-type corrugation Plate Heat Exchanger (PHE) was designed. Results from both numerical simulations and experiments showed that the flow resistance of the working fluid in this new corrugation PHE, compared with the traditional chevron-type one, was decreased by more than 50%, and corresponding heat transfer performance was decreased by about 25%. The flow field of the working fluid in the corrugation PHE was transformed and hence performance difference in both flow resistance and heat transfer was generated. Such a novel plate, consisting of longitudinal and transverse corrugations, can effectively avoid the problem of flow path blockage, which will help to extend the application of PHEs to the situation with unclean working fluids. | LUAN Zhi-jian ZHANG Guan-min TIAN Mao-cheng FAN Ming-xiu | 2008 | Journal of Hydrodynamics2008，20，4： | 11 |
| 14 | Dongsha erosive channel on northern South China Sea Shelf and its induced Kuroshio South China Sea Branch显示文摘Based on a data base of multi-channel seismic profiles covered over Dongsha plateau of the northern South China Sea margin, we found that the sea bed morphology of northern South China Sea margin had been changed dramatically after Dongsha uplifting, that sedimentary layer since Miocene age had been eroded with maximum eroded thickness more than 1000 m, and that an erosive channel had been formed of 20 km in width and 200 km in length and several hundreds meters in depth on the outer shelf of northern South China Sea. The erosive channel is parallel to the 600 m isobath line, stretching from northeast to the southwest north of Dongsha uplift. The Kuroshio intrudes the South China Sea through Luzon Strait both in winter time and summer time, and in the northern South China Sea margin area, the intruded Kuroshio Branch takes the form of Pacific-Indian Ocean Through Flow (PITH) in winter time, while the Luzon Strait Subsurface Inflow (LSSIF) in summer time, the routes of both PITH and LSSIF coincide well with the distribution of the erosive channel. After climbing from the northern slope up to the northern shelf, and after joined by the southward flow from the middle northern shelf of South China Sea, the Kuroshio Branch is strengthened and thus is able to erode the sea floor, and the shape of the erosive channel is a result of the long-term interaction between the Kuroshio South China Sea Branch and the Dongsha outer shelf sea floor. | LUAN XiWu ZHANG Liang PENG XueChao | 2012 | Science China Earth Sciences2012，55，1： | 11 |
| 15 | Re-identifying Grateloupia yangjiangensis(Rhodophyta, Halymeniaceae) based on morphological observations, life history and rbcL sequence analyses显示文摘On the basis of morphological observations, life history and molecular phylogeny, Grateloupia yangjiangensis, which is similar to G. filicina, G. orientalis, G. catenata, and G. ramosissima in appearance, was re-examined. The results are as follows:(1) the auxiliary-cell ampullae of G. yangjiangensis were of Grateloupia type, thalli was fleshy and gelatinous in texture, and the erect axes were compressed; the cortex was 0.25–0.30 mm thick, consisting of five to seven outer layers, and there were five inner layers of triangular or stellate cells;(2) there was no filamentous stage in the development of the carpospores;(3) the ribulose-1,5-bisphosphate carboxylase/oxygenase gene(rbcL) sequence of four G. yangjiangensis examined showed that there was no intergeneric divergence among them, and for the phylogenetic tree, four sequences of G. yangjiangensis formed a single monophyletic subclade within the large Grateloupia clade of Halymeniaceae. In conclusion, G. yangjiangensis was a single species within the genus Grateloupia. This research provided criterion for identification and cultivation of G. yangjiangensis. | WANG Hongwei GUO Shaoru ZHANG Xiaoming ZHAO Dan ZHANG Wen LUAN Rixiao | 2014 | Acta Oceanologica Sinica2014，33，4： | 10 |
| 16 | Impact of Smoking on Anal Abscess and Anal Fistula Diseases显示文摘 | Li-Hua Zheng Ao-Zhe Zhang Yu-Ying Shi Xin Li Lan-Si Jia Cong-Cong Zhi Qiu-Xiang Yu Wen Zhang Yan-Jun Liu Luan Wang Dan Xiao Chen Wang | 2018 | Chinese Medical Journal2018，，9： | 10 |
| 17 | Identification of Orientia tsutsugamushi,spotted fever group and typhus group Rickettsia by duplex and nested PCR methods显示文摘Objective:To identify members of genera of rickettsia and O.tsutsugammhi simultaneously.Methods:Rapid and duplex and nested PCR methods have been established by designing primers based on the conserved regions of heat shock protein GroEL gene.345 mouse viscera samples including liver,spleen and kidney,96 Xenopsylla cheopis and 32 chiggers collected from Hongta areas of Yuxi city,Yunnan province were tested by the new PCR methods.Results:The result of the study showed that the new PCR methods could identify most members of genera -Rickettsia and Orientia simultaneously with 100%specificity and its sensitivity could test one copy per microliter.The results of detection prevalence of rickettsioses in mouse,flea and mites DNA samples showed that the total rickettsia infection rate in mouse was 34.78%(120/345).The total infection rates in R.typhi,O.t Karp and R.sibirica of mouse samples were 28.12%(97/345),19.71%(68/345) and O. 29%(1/345) respectively.Co-infection rates in R.typhi and 0.t Karp of mouse samples were 13.33%(46/ 345).O.t Karp type has been the main epidemic strain in these areas.Conclusion:We concluded that this PCR method could be used to detect multi-genera rickettsia simultaneously.Molecular evidences provided in this and previous studies strongly support that Hongta areas of Yuxi city are a natural focus for typhus and scrub typhus with the common occurrence of their confection. | M-C Luan D-Z Yu L Tang L-J Zhang | 2008 | Asian Pacific Journal of Tropical Medicine2008，1，4： | 10 |
| 18 | Long-term outcomes of drug-eluting versus bare-metal stent implantation in patients with chronic total coronary artery occlusions显示文摘在那里的背景为长期的全部的吸藏(CTO ) 的治疗是 drug-eluting stents (DES ) 的功效上的有限数据。学习的目的是与赤裸金属的 stent ( BMS )相比为 CTO 评估 DES 培植的长期的临床的结果在1995年6月和2006年12月之间的 implantation.Methods ,有至少一 de novo CTO 损害的成功的开运河的 1184 个病人的一个总数连续地被登记,包括 660 (55.7%)经历了 DES 并且 524 (44.3%)经历了 BMS 培植。所有病人被跟随在上面为为主要不利心脏的事件(向) 的出现的多达 5 年。长期的幸存率与临床的 Kaplan-Meier method.Results 基线被估计,除了在 DES 组的病人收到了更长双的 antiplatelet 治疗之外, angiographic 特征在二个组之间是可比较的((7.4 ??????????????? 陈 ? 陈吗?? | HAN Ya-ling ZHANG Jian LI Yi WANG Shou-li JING Quan-min YI Xian-hua MA Ying-yan LUAN Bo WANG Geng WANG Bin | 2009 | Chinese Medical Journal2009，，6： | 9 |
| 19 | Expression of human cytomegalovirus components in the brain tissues of patients with Rasmussen's encephalitis显示文摘Rasmussen's encephalitis(RE) is a rare and severe progressive epileptic syndrome with unknown etiology. Infection by viruses, including human cytomegalovirus(HCMV), has been speculated to be a potential trigger for RE. However, no viral antigens have been detected in the brains of patients with RE; thus, a possible clinical linkage between viral infections and RE has not been firmly established. In this study, we evaluated the expression of HCMV pp65 antigen in brain sections from 26 patients with RE and 20 non-RE patients by immunohistochemistry and in situ hybridization, and assessed the associations between HCMV infection and clinical parameters.Elevated expression of HCMV pp65 protein and DNA was observed in 88.5%(23/26) and 69.2%(18/26) of RE cases, respectively. In the non-RE group, HCMV pp65 antigen was detected only in two cases(10%), both of which were negative for DNA staining. Additionally, the intensity of HCMV pp65 staining was correlated with a shorter duration of the prodromal stage, younger age of seizure onset, and more severe unilateral cortical atrophy. Elevated expression of HCMV pp65 was observed in RE brain tissue and was correlated with the clinical features of RE disease. In summary, our results suggested that HCMV infection may be involved in the occurrence and progression of RE disease. Thus, further studies are needed to determine whether early treatment with anti-HCMV antibodies could modulate the course of RE. | Yao Zhang Yisong Wang Sichang Chen Shuai Chen Yuguang Guan Changqing Liu Tianfu Li Guoming Luan Jing An | 2017 | Virologica Sinica2017，32，2： | 9 |
| 20 | Effect of total aluminum concentration on the formation and transformation of nanosized Al_(13) and Al_(30) in hydrolytic polymeric aluminum aqueous solutions显示文摘Influence of total aluminum concentration (CAlT) on the generation and transformation of nanosized Al13 and Al30 in hydrolytic polyaluminum aqueous solutions was in-vestigated using high field 27Al NMR and time-developed Al-Ferron complex colorimetry. When prepared at the opti-mal basicity (B) of Al13 generation and 80℃, the Al13 species in polyaluminum solution tends to further polymerize and convert to Al30 and higher polymers when CAlT >0.2 mol·L?1, but Al13 does not convert to Al30 quantificationally, as the formation of Alu from Al13 and Al30 is accelerated in the same way. The conversion rate of Al13 is accelerated by the in-crease in CAlT. When CAlT >0.75 mol·L?1, Al13 content de-creases rapidly, and Al30 content increases continuously and becomes the dominant nanometer polynuclear aluminum species. Alm is one of prerequisites of Al13 conversion to Al30. When CAlT increases and B reduces, the polymerization rate between Al13 and Alm increases, and at the same time, the dissociation reaction rate of Al13 and Al30 by H+ also increases. The latter becomes the dominant reaction in polyaluminum solution with low B value, so Al30 decreases with the increas-ing CAlT. The hydrolytic polyaluminum solution with Al13 content beyond 80% can only be prepared under the condi-tion of CAlT<0.5 mol·L?1 and optimal B value. | CHEN Zhaoyang LIU Changjun LUAN Zhaokun ZHANG Zhongguo LI Yanzhong JIA Zhiping | 2005 | Chinese Science Bulletin2005，50，18： | 8 |
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