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| 1 | Synthesis of CNT film on the surface of micro-pyramid array and its intense pulsed emission characteristics显示文摘We developed a new scheme to suppress the electric-field-screening effect in high growth density of a carbon nanotube(CNT) film during its intense pulsed emission.We synthesize the CNT film on a tridimensional surface(t-CNT film).The tridimensional surface includes wet etched silicon pyramids,and the Ni layer is electroless plated thereon.The intense pulsed emission characteristics of the t-CNT and planar-grown CNT(p-CNT) films were measured using a diode structure in single-pulse mode.The even turn-on field decreased from 5.5 V/μm for p-CNTs to 2.8 V/m for t-CNTs,and the peak emission current increased from 232 A for p-CNTs to 324 A for t-CNTs at a peak field intensity ~12.2 V/m.The peak current of the t-CNT film increased by ~39.7% over the p-CNT film.It is clear that the micro-pyramid array can effectively suppress the field screening effect to improve the electron-emission of CNT films. | ZENG FanGuang LI Xin LIU WeiHua QIAO ShuZhen MA HuaLi ZHANG Rui XIA LianSheng CHEN Yi LIU XingGuang ZHANG Huang | 2012 | Chinese Science Bulletin2012，57，14： | 10 |
| 2 | Improvement in the intense pulsed emission stability of grown CNT films via an electroless plated Ni layer显示文摘Carbon nanotube(CNT)films were grown on silicon wafers with and without a nickel layer(Si-CNT and Ni-CNT)via the pyrolysis of iron phthalocyanine.The nickel layer was prepared using the electroless plating method.To study the emission stability of Si-CNT and Ni-CNT cathodes during intense pulsed emission,emission characteristics were measured repeatedly with a diode structure using a Marx generator as a voltage source.For the peak values of the pulsed voltage,which were in the range between 1.62-1.66 MV(corresponding to electric field intensities between 11.57-11.85 V/μm),the first cycle emission current was 109.4 A for Si-CNT and 180.5 A for Ni-CNT.By comparing the normalized emission currents of the Si-CNT and Ni-CNT cathodes,the improvement in the emission stability can be easily quantified.The number of emission cycles necessary for the peak current to decay from 100%to 50%increased from^3 for Si-CNT to^11 for a Ni-CNT film. | ZENG FanGuang LI Xin LIU WeiHua QIAO ShuZhen MA HuaLi ZHANG Rui XIA LianSheng CHEN Yi LIU XingGuang ZHANG Huang | 2011 | Chinese Science Bulletin2011，56，22： | 7 |
| 3 | Identification of human LDHC4 as a potential target for anticancer drug discovery显示文摘One of the distinct hallmarks of cancer cells is aerobic glycolysis(Warburg effect). Lactate dehydrogenase A(LDHA) is thought to play a key role in aerobic glycolysis and has been extensively studied, while lactate dehydrogenase C(LDHC), an isoform of LDHA, has received much less attention.Here we showed that human LDHC was significantly expressed in lung cancer tissues, overexpression of Ldhc in mice could promote tumor growth, and knock-down of LDHC could inhibit the proliferation of lung cancer A549 cells. We solved the first crystal structure of human LDHC4 and found that the activesite loop of LDHC4 adopted a distinct conformation compared to LDHA4 and lactate dehydrogenase B4(LDHB4). Moreover, we found that(ethylamino)(oxo)acetic acid shows about 10 times selective inhibition against LDHC4 over LDHA4 and LDHB4. Our studies suggest that LDHC4 is a potential target for anticancer drug discovery and(ethylamino)(oxo)acetic acid provides a good start to develop lead compounds for selective drugs targeting LDHC4. | Hong Tan Huali Wang Jinhu Ma Hui Deng Qinghua He Qiang Chen Qinglian Zhang | 2022 | Acta Pharmaceutica Sinica B2022，12，5： | 2 |
| 4 | A methodology for evaluating enter prises informatization in Chinese manufacturing enterprises显示文摘 | HUALI CHEN DENGZHE MA | 2004 | International journal of manufacturing technology2004，23，3： | 1 |
| 5 | A continuous thermal lysis procedure for the large-scale preparation of plasmid DNA 显示文摘 | Kaichun Zhu Huali Jin Yijie Ma | 2005 | Journal of Biotechnology2005，118，： | 1 |
| 6 | A methodology for evaluating enterprises informatization in Chinese manufacturing enterprises显示文摘 | Huali Chen Dengzhe Ma | 2004 | International journal of manufacturing technology2004，23，3： | 1 |
| 7 | Influ- ence of different buffer layer on intense pulsed field e- mission of carbon nanotubes显示文摘 | Ma Huali Zhang Xinyue Qiao Shuzhen | 2012 | Advanced Materials Research2012，586，： | 1 |
| 8 | Oriented Generation of Novel Thermo-Sensitive Genic Male Sterile Lines with Improved Grain Shape and Outcrossing Rate in Early-Season Rice显示文摘Two-line hybrid rice with excellent quality is preferred in the Chinese market.However,there is a trade-off between reducing costs for hybrid seed production and lowering the outcrossing rate of the sterile line,which is largely determined by the stigma exsertion rate(SER).In this study,we constructed mutants of male sterility lines with improved grain length(GL)and SER in three elite early-season indica rice varieties through targeted manipulation of the TMS5 and GS3 genes using CRISPR/Cas9-mediated multiplex systems.We obtained a series of marker-free gs3 single mutants and gs3tms5 double mutants with significantly higher SER,longer grains,and increased 1000-grain weight compared with the wild type(WT).Importantly,the typically thermo-sensitive genic male sterile(TGMS)trait with a higher SER was observed in gs3tms5 mutants,and their F1 hybrids exhibited remarkable improvements in grain shape and yield-related traits.Our findings provided an efficient method to generate new valuable TGMS germplasm with improved SER through the mutagenesis of GS3 and TMS5 synergistically,and demonstrated that GS3 had pleiotropic effects on grain size,SER,and grain quality in early-season indica rice. | ZHANG Huali CHEN Junyu LI Ruiqing WANG Huimei DAI Dongqing LIANG Minmin WU Mingyue MA Liangyong | 2024 | Rice science2024，31，2： | 0 |
| 9 | Prevalence of dementia and the attributable contributions of modifiable risk factors in China显示文摘With the largest ageing population in the world,China is faced with the huge chal-lenge of dementia.-However,previously reported estimates on the prevalence of dementia among Chinese older adults were inconsistent,varying from 2%to 13%.5°It is crucial for dementia prevention to determine the number of cases that could be delayed or prevented,but how to do this remains unclear.To address these research gaps,we aimed to provide population estimates of the prevalence of dementia in China and estimate the population attributable fractions(PAFs)of potentially modifiable risk factors. | Hui Chen Yuhui Huang Xiaozhen Lv Xin Xu Yuan Ma Huali Wang Changzheng Yuan | 2023 | General Psychiatry2023，36，3： | 0 |
| 10 | A backbone parent contributes core genomic architecture to pedigree breeding of early-season indica rice显示文摘Due to the capacity to deliver favorable target traits to offspring via breeder selection,backbone parents carrying accumulated favorable agronomic traits have been used widely in breeding programs in crop species,such as rice,wheat,cotton,and maize(Zhou et al.,2016;Fradgley et al.,2019;Li et al.,2019;Ma et al.,2019;Han et al.,2020).It is estimated that 3656(~70%)of the major Chinese rice varieties released from the year 1950e2008 were found to be derived from as few as 35 backbone parents(Tang et al.,2012).Large-scale genome sequencing of diverse rice accessions has been emerged as a promising technology for the identification of key genomic regions or loci under selection during rice domestication(Huang et al.,2012;Wang et al.,2018)and genetic improvement(Xie et al.,2015).On the other hand,sequence information derived from breeding pedigrees could also help to unravel how favorable genomic regions were transmitted from parents to their offspring,as demonstrated by the researches on the pedigrees of the wellknown rice varieties Minghui 63 and Huanghuazhan(Zhou et al.,2016;Chen et al.,2017;Huang et al.,2018).These researches enhanced the understanding of the cumulative effects of beneficial alleles at limited loci in selected offspring varieties.A few examples include IPA1,Gn1a,GW5,GS3,and GS5 for high grain yield,Waxy for good grain eating quality,and Xa21 for high adversity adaptability. | Junyu Chen Huali Zhang Shuhan Deng Huilong Du Zhuo Chen Yuhui Zhao Dongqing Dai Chengzhen Liang Ximing Li Chengzhi Liang Rui Zhang Liangyong Ma | 2021 | Journal of Genetics and Genomics2021，48，11： | 0 |
| 11 | Preparation of nZVI embedded modified mesoporous carbon for catalytic persulfate to degradation of reactive black 5显示文摘High-efficiency and cost-effective catalysts with available strategies for persulfate(PS)activation are critical for the complete mineralization of organic contaminants in the environmental remediation and protection fields.A nanoscale zero-valent iron-embedded modified mesoporous carbon(MCNZVI)with a core-shell structure is synthesized using the hydrothermal synthesis method and high-temperature pyrolysis.The results showed that nZVI could be impregnated within mesoporous carbon frameworks with a comparatively high graphitization degree,rich nitrogen doping content,and a large surface area and pore volume.This material was used as a persulfate activator for the oxidation removal of Reactive Black 5(RB5).The effects of the material dosage,PS concentration,pH,and some inorganic anions(i.e.,Cl^(−),SO_(4)^(2−))on RB5 degradation were then investigated.The highest degradation efficiency(97.3%)of RB5 was achieved via PS(20 mmol/L)activation by the MCNZVI(0.5 g/L).The pseudo-first-order kinetics(k=2.11×10^(−2)min^(−1))in the MCNZVI/PS(0.5 g/L,20 mmol/L)was greater than 100 times than that in the MCNZVI and PS.The reactive oxygen species(ROS),including^(1)O_(2),SO_(4)^(·−),HO^(.),and·O_(2)^(−),were generated by PS activation with the MCNZVI.Singlet oxygen was demonstrated to be the primary ROS responsible for the RB5 degradation.The MCNZVI could be reused and regenerated for recycling.This work provides new insights into PS activation to remove organic contamination. | Zhifei Ma Huali Cao Fengchun Lv Yu Yang Chen Chen Tianxue Yang Haixin Zheng Daishe Wu | 2021 | Frontiers of Environmental Science & Engineering2021，15，5： | 0 |
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