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| 1 | A distributed cooperative guidance law for salvo attack of multiple anti-ship missiles显示文摘The consensus problem of impact time is addressed for multiple anti-ship missiles. A new distributed cooperative guidance law with the form of biased proportional navigation guidance(BPNG) is presented. The proposed guidance law employs the available measurements of relative impact time error as the feedback information to achieve the consensus of impact time among missiles and, by exploiting the special structure of the biased cooperative control term, it can handle the seeker's field-of-view(FOV) constraint. The proposed scheme ensures convergence to consensus of impact time under either fixed or switching sensing/communication network, and the topological requirements are less restrictive than those in the existing results. Numerical examples are provided to illustrate the effectiveness of the proposed guidance law. | Zhang Youan Wang Xingliang Wu Huali | 2015 | Chinese Journal of Aeronautics2015，28，5： | 25 |
| 2 | A New Darwinopterid Pterosaur from the Middle Jurassic of Western Liaoning,Northeastern China and its Ecological Implications显示文摘Darwinopterus 的新种, D。robustodens sp。nov。被描述并且说出。基于新标本, Darwinopterus 的诊断人物被修改并且包括:喙的出牙好空间的、穗状的牙齿创作了;最长的牙齿被限制到牙齿排的前面的一半;牙齿 alveoli 提起了边缘;nasoantorbital 窗汇合;倾向适合;伸长有低神经脊骨的颈的 vertebrae 并且减少或不在的肋骨;超过 20 caudals 的长尾巴部分由 pre- 和 postzygapophyses 的丝状的延期围住;短掌肱骨的不到 60% 长度,有二的第五个脚趾伸长指骨和有在近似、远侧的片断之间的角度的第五个脚趾的弄弯的秒踏脚板方阵大约 130 度。新翼龙 D 的完全的标本。robustodens sp。nov。提供更骨学的信息。在在 Darwinopterus modularis 和 D 之间的牙齿形态学的差别。robustodens sp。nov。建议他们充满了不同生态的壁龛。努力忍受覆盖物的翘目可以是 Darwinopterus robustodens 的主要食物来源。 | Lu Junchang XU Li CHANG Huali ZHANG Xingliao | 2011 | Acta Geologica Sinica(English Edition)2011，85，3： | 13 |
| 3 | Synthesis of CNT film on the surface of micro-pyramid array and its intense pulsed emission characteristics显示文摘We developed a new scheme to suppress the electric-field-screening effect in high growth density of a carbon nanotube(CNT) film during its intense pulsed emission.We synthesize the CNT film on a tridimensional surface(t-CNT film).The tridimensional surface includes wet etched silicon pyramids,and the Ni layer is electroless plated thereon.The intense pulsed emission characteristics of the t-CNT and planar-grown CNT(p-CNT) films were measured using a diode structure in single-pulse mode.The even turn-on field decreased from 5.5 V/μm for p-CNTs to 2.8 V/m for t-CNTs,and the peak emission current increased from 232 A for p-CNTs to 324 A for t-CNTs at a peak field intensity ~12.2 V/m.The peak current of the t-CNT film increased by ~39.7% over the p-CNT film.It is clear that the micro-pyramid array can effectively suppress the field screening effect to improve the electron-emission of CNT films. | ZENG FanGuang LI Xin LIU WeiHua QIAO ShuZhen MA HuaLi ZHANG Rui XIA LianSheng CHEN Yi LIU XingGuang ZHANG Huang | 2012 | Chinese Science Bulletin2012，57，14： | 10 |
| 4 | Rescued virus from infectious cDNA clone of rabbit hemorrhagic disease virus is adapted to RK13 cells line显示文摘Based on the infectious full-length cDNA clone of rabbit hemorrhagic disease virus (RHDV), the in vitro transcripts are introduced into RK13 cells. 12 h later, CPE could be observed clearly, and virual antigen could also be detected by IFA. The titre of the recovered virus is 104.6/mL. Immune electron micro-scopic observation of the virus particles revealed that the particles were rotund with a diameter of about 30 nm. Besides, virus titre quantification obtained by qRT-PCR showed a correlation between time from infection and virus titre. All these results showed that we have recovered RHDV from RK13 cells by re-verse genetics technology successfully, and this would be very useful in studies of the antigenicity, virulence, pathogenesis, maturation and new type vaccines of RHDV. | LIU Guangqing NI Zheng YUN Tao ZHANG Yuying DU Qingyun SHENG Zutian LIANG Huali HUA Jionggang LI Shuangmao Chen Jianping | 2006 | Chinese Science Bulletin2006，51，14： | 9 |
| 5 | Ni-Co/Mg-Al catalyst derived from hydrotalcite-like compound prepared by plasma for dry reforming of methane显示文摘Ni-Co bimetallic catalysts with different Ni/Co content were derived from cold plasma jet decomposition and reduction of hydrotalcite-like compounds containing Ni,Co,Mg and Al,and their catalytic performance was investigated with dry reforming of methane.Experimental results showed that the hydrotalcite-like precursors could be completely decomposed and partly reduced by cold plasma jet,and the Nicontained catalysts exhibited much higher activity than the catalyst without Ni.Especially,the catalyst with Ni/Co ratio of 8/2 achieved not only the highest conversions of 80.3%and 69.3%for CH4 and CO2,respectively,but also the best stability in 100 h testing.The catalysts were characterized by XRD,XPS,TEM and N2 adsorption techniques,and the results showed that the better performance of the 8Ni2Co bimetallic catalyst was attributed to its higher metal dispersion,smaller metal particle size,as well as the interaction effect between Ni and Co,which were brought by the special catalyst preparation method. | Huali Long Yan Xu Xiaoqing Zhang Shijing Hu Shuyong Shang Yongxiang Yin Xiaoyan Dai | 2013 | Journal of Energy Chemistry2013，22，5： | 8 |
| 6 | Comparison of alternative extraction methods for secretome profiling in human hepatocellular carcinoma cells显示文摘Secreted proteins are important sources for early detection and diagnosis of disease, and as such have received considerable attention. The extraction of low concentration proteins from large volumes of culture media, which are rich in salts and other compounds that interfere with most proteomics techniques, presents a problem for secretome studies. Ultrafiltration, precipitation, and dialysis are three major extraction methods that can be used to overcome this problem. The present study for the first time, compared the merits and shortcomings of these three methods, without bias. Centrifugal ultrafiltration provided the best extraction efficiency, and precipitation provided the highest number of identifiable proteins. The three methods yielded closely related, but different, information on the secretome; thus, they should be considered complementary or, at least, supplementary methods. Three hundred and sixty unique proteins were identified, including 211 potential secreted proteins. Compared with previous studies, this study also identified 42 new secreted proteins. The present study not only offers a reference for the selection of secretome extraction methods, but also expands the secretome database for the investigation of hepatocellular carcinoma. | CAO Jing SHEN ChengPin ZHANG Jun YAO Jun SHEN HuaLi LIU YinKun LU HaoJie YANG PengYuan | 2011 | Science China(Life Sciences)2011，54，1： | 8 |
| 7 | Improvement in the intense pulsed emission stability of grown CNT films via an electroless plated Ni layer显示文摘Carbon nanotube(CNT)films were grown on silicon wafers with and without a nickel layer(Si-CNT and Ni-CNT)via the pyrolysis of iron phthalocyanine.The nickel layer was prepared using the electroless plating method.To study the emission stability of Si-CNT and Ni-CNT cathodes during intense pulsed emission,emission characteristics were measured repeatedly with a diode structure using a Marx generator as a voltage source.For the peak values of the pulsed voltage,which were in the range between 1.62-1.66 MV(corresponding to electric field intensities between 11.57-11.85 V/μm),the first cycle emission current was 109.4 A for Si-CNT and 180.5 A for Ni-CNT.By comparing the normalized emission currents of the Si-CNT and Ni-CNT cathodes,the improvement in the emission stability can be easily quantified.The number of emission cycles necessary for the peak current to decay from 100%to 50%increased from^3 for Si-CNT to^11 for a Ni-CNT film. | ZENG FanGuang LI Xin LIU WeiHua QIAO ShuZhen MA HuaLi ZHANG Rui XIA LianSheng CHEN Yi LIU XingGuang ZHANG Huang | 2011 | Chinese Science Bulletin2011，56，22： | 7 |
| 8 | Temporal-spatial dynamics of distribution patterns of microorganism relating to biological soil crusts in the Gurbantunggut Desert显示文摘生物土壤外壳用作贡献沙固定的一个重要生物因素。这研究被进行在关于地点的外壳中调查微生物的时间空间的可变性,沙沙丘和季节的土壤层。在苔藓主导的内部沙丘的区域,更高的土壤营养素和水集中是可能的维持微生物引起的活动。细菌显示出解决和生长的最高的能力在在春天和秋天内部沙丘。土壤水内容在内部沙丘的区域在土壤外壳中到达了最高的价值,特别在春天。放线菌和真菌的数量的变化基本上在沙沙丘的不同地点显示出一致趋势。与加深土壤层,因为环境因素在春天和秋天波动,每个微生物组的数量的垂直分发显示出不同特征。在不同微生物组之中,细菌是占优势的,在在所有的春天和秋天的放线菌下一个和真菌最少玷污层(020 厘米) 。细菌和土壤水内容的比例比在在所有土壤层(020 厘米) 的秋天的那些在春天是更高的。没有一致趋势在放线菌和真菌被发现。结果证明微生物的数量是显著地积极的与有机物内容相关,土壤水满意的、全部的 N,全部的 P,可得到的 P,可得到的 K, pH,电的传导性,全部的盐内容,过氧化氢酶, urease,磷酸酶和碱的磷酸酶。 | WU Nan WANG Hongling LIANG Shaoming NIE Huali ZHANG Yuanming | 2006 | Chinese Science Bulletin2006，51，A01： | 7 |
| 9 | Gene Cloning and Expression of the Pyrroline-5-carboxylate Reductase Gene of Perennial Ryegrass(Lolium perenne)显示文摘Salt and drought limit the range of applications of perennial ryegrass(Lolium perenne L.), which is one of the important turf and forage grasses. Previous studies have suggested that pyrroline-5-carboxylate reductase(P5CR) might play a central role in proline accumulation in plants that are responsive to stresses. In the present study, the Lolium perenne L. pyrroline-5-carboxylate reductase(LpP 5CR) gene was cloned from leaves of the cultivar ‘Derby' using the RACE technique. The full-length LpP 5CR gene was 1 047 bp in length, which comprised an open reading frame(ORF) of 840 bp in size. Sequence alignment revealed that the putative Lp P5 CR had a 94.3% similarity to Ta P5 CR. q RT-PCR displayed that the mR NA levels of the LpP 5CR gene were almost the same as that in the roots, stems, and leaves of perennial ryegrass seedlings subjected to normal condition or NaC l treatment for 1 h. Moreover, the transcription level of LpP 5CR was up- or down- regulated with Na Cl, polyethylene glycol(PEG), cold, or abscisic acid(ABA) treatment for 3 to 48 h. In addition, confocal microscopy localized the GFP-Lp P5 CR fusion protein to the cytoplasm of onion epidermal cells. These findings suggest that LpP 5CR encodes a cytoplasmic P5 CR protein that plays an important role in the response of perennial ryegrass to various stresses. | CAO Li WEI Shuqiang HAN Lei QIAN Yongqiang ZHANG Huali XIN Haibo SUN Zhenyuan | 2015 | Horticultural Plant Journal2015，1，2： | 7 |
| 10 | The calcium-dependent protein kinase ZmCDPK7 functions in heat-stress tolerance in maize显示文摘Global warming poses a serious threat to crops.Calcium-dependent protein kinases(CDPKs)/CPKs play vital roles in plant stress responses,but their exact roles in plant thermotolerance remains elusive.Here,we explored the roles of heat-induced ZmCDPK7 in thermotolerance in maize.ZmCDPK7-overexpressing maize plants displayed higher thermotolerance,photosynthetic rates,and antioxidant enzyme activity but lower H2 O2 and malondialdehyde(MDA)contents than wild-type plants under heat stress.ZmCDPK7-knockdown plants displayed the opposite patterns.ZmCDPK7 is attached to the plasma membrane but can translocate to the cytosol under heat stress.ZmCDPK7 interacts with the small heat shock protein sHSP17.4,phosphorylates sHSP17.4 at Ser-44 and the respiratory burst oxidase homolog RBOHB at Ser-99,and up regulates their expression.Site-directed mutagenesis of sHSP17.4 to generate a Ser-44-Ala substitution reduced ZmCDPK7’s enhancement of catalase activity but enhanced ZmCDPK7’s suppression of MDA accumulation in heat-stressed maize protoplasts.sHSP17.4,ZmCDPK7,and RBOHB were less strongly upregulated in response to heat stress in the abscisic acid-deficient mutant vp5 versus the wild type.Pretreatment with an RBOH inhibitor suppressed sHSP17.4 and ZmCDPK7 expression.Therefore,abscisic acid-induced ZmCDPK7 functions both upstream and downstream of RBOH and participates in thermotolerance in maize by mediating the phosphorylation of sHSP17.4,which might be essential for its chaperone function. | Yulong Zhao Hanwei Du Yankai Wang Huali Wang Shaoyu Yang Chaohai Li Ning Chen Hao Yang Yihao Zhang Yulin Zhu Luyao Yang Xiuli Hu | 2021 | Journal of Integrative Plant Biology2021，63，3： | 6 |
| 11 | Nuclear proteome profile of C57BL/6J mouse liver显示文摘The liver proteome can serve as a reference to better understand both disease mechanisms and possible therapeutics,since the liver is an important organ in the body that performs a large number of tasks.Here we identify the organelle proteome of C57BL/6J mouse liver nuclei as a promising strategy to enrich low abundance proteins,in the sense that analysis of whole liver cells is rather complex for current techniques and may not be suitable for proteins with low abundance.Evaluation of nucleus integrity and purity was performed to demonstrate the effectiveness of the optimized isolation procedure.The extracted nuclear proteins were identified by 2-DE MS analyses,and a total of 748 proteins were identified.Bioinformatic analyses were performed to demonstrate the physicochemical properties,cellular locations and functions of the proteins. | ZHANG Yang FANG CaiYun BAO HuiMin FAN HuiZhi SHEN HuaLi YANG PengYuan | 2013 | Science China(Life Sciences)2013，56，6： | 3 |
| 12 | Enhanced photocatalytic degradation of organic contaminants over CaFe_(2)O_(4) under visible LED light irradiation mediated by peroxymonosulfate显示文摘A simple sol-gel approach is proposed herein to fabricate CaFe_(2)O_(4)for the degradation of various organic pollutants(rhodamine B(RhB),tetracycline hydrochloride,humic acid,and methylene orange)under LED light irradiation mediated by peroxymonosulfate(PMS).The results indicate that the calcination temperature can significantly influence the performance of CaFe_(2)O_(4)for PMS activation,and the CaFe_(2)O_(4)sample obtained at 800℃(CaFe_(2)O_(4)-800)exhibits the best efficiency in degrading RhB,which is much higher than that of Fe_2o_(3)-800.This can be attributed to the efficient separation of photogenerated electrons(e^(-))and holes(h^(+))by PMS,which is validated by transient photocurrent response and photoluminescence measurements.Results from density functio nal theo ry calculations indicate that the valence band of CaFe_(2)O_(4)-800 exhibits a high concentration of carriers and weak localization of electrons,which are favorable for PMS activation.Radical scavenging results confirm that h^(+)and O_(2)^(·-)are the dominant reactive species.Moreover,CaFe_(2)O_(4)-800 not only demonstrated a stable performance during eight cycling runs with negligible iron leaching but also exhibited excellent degradation efficiency under natural water and sunlight.Finally,the mechanism and pathway of RhB degradation by the CaFe_(2)O_(4)-800/PMS/LED system are also proposed.This work presents the enormous prospect of CaFe_(2)O_(4)as an environmentally benign photocatalyst for PMS activation. | Sheng Guo Zhixiong Yang Huali Zhang Wei Yang Jun Li Kun Zhou | 2021 | Journal of Materials Science & Technology2021，，3： | 3 |
| 13 | Characteristics and Driving Forces of Spatial Expansion of Oasis Cities and Towns in Hexi Corridor, Gansu Province, China显示文摘This paper presents an integrated study of urban spatial expansion in the Hexi Corridor, Gansu Province, China based on TM, ETM remote sensing data in 1987, 1990, 1995, 2000, 2006 and 2011. The study explores the characteristics of urban spatial expansion and dynamic mechanism by using expansion speed index, expansion intensity index, compact index, fractal dimension, and extended flexibility index. We built the index system of influencing factors of urban spatial expansion by using the grey incidence model. The results showed that urban spatial expansion rate in the Hexi Corridor has been on the upward trend since 1987. Expansion intensity showed an obvious upward trend, however, the upward trend varied in different urban areas. In addition, the urban structure was loose relatively, but the urban compactness was more obvious. The urban spatial form tended to be simple, and the urban land use tended to become more intensive. Urban spatial expansion experienced several stages: padding internally, external expansion and padding internally. The main driving factors of urban spatial expansion are not the urban water resources and the oasis scale, but one or several factors such as economy, traffic, population, resource and national policy. | LIU Hailong SHI Peiji TONG Huali ZHU Guofeng LIU Haimeng ZHANG Xuebin WEI Wei WANG Xinmin | 2015 | Chinese Geographical Science2015，25，2： | 3 |
| 14 | Identification of human LDHC4 as a potential target for anticancer drug discovery显示文摘One of the distinct hallmarks of cancer cells is aerobic glycolysis(Warburg effect). Lactate dehydrogenase A(LDHA) is thought to play a key role in aerobic glycolysis and has been extensively studied, while lactate dehydrogenase C(LDHC), an isoform of LDHA, has received much less attention.Here we showed that human LDHC was significantly expressed in lung cancer tissues, overexpression of Ldhc in mice could promote tumor growth, and knock-down of LDHC could inhibit the proliferation of lung cancer A549 cells. We solved the first crystal structure of human LDHC4 and found that the activesite loop of LDHC4 adopted a distinct conformation compared to LDHA4 and lactate dehydrogenase B4(LDHB4). Moreover, we found that(ethylamino)(oxo)acetic acid shows about 10 times selective inhibition against LDHC4 over LDHA4 and LDHB4. Our studies suggest that LDHC4 is a potential target for anticancer drug discovery and(ethylamino)(oxo)acetic acid provides a good start to develop lead compounds for selective drugs targeting LDHC4. | Hong Tan Huali Wang Jinhu Ma Hui Deng Qinghua He Qiang Chen Qinglian Zhang | 2022 | Acta Pharmaceutica Sinica B2022，12，5： | 2 |
| 15 | Identification and characterization of human neuronal voltage-gated calcium channel gamma 3 subunit gene显示文摘By homologous expressed sequence tag (EST) searching, one EST (GenBank: W29095) was obtained, which shows 75% identity in 435 bp overlap with the coding sequence of mouse Cacng2 gene. A 1 545 bp cDNA fragment was obtained from the nested polymerase chain reaction (PCR) and rapid applification of cDNA end (RACE) reaction in the human brain prefrontal cortex cDNA library and the human brain Ready cDNA with the primers designed on W29095. The fragment contained a 948-bp open reading frame (ORF) encoding 315 amino acids, and was named CACNG3. As it was identical to a BAC clone (GenBank: AC004125) from chromosome 16p12-p13.1, the CACNG3 gene was mapped to human chromosome 16p12-p13.1, and the coding region was composed of 4 exons. Reverse transcription PCR (RT-PCR) analysis showed that the CACNG3 gene expressed in human adult brain and fetal brain. Single strand comformation polymorphism (SSCP) analysis was performed in 3 pedigrees with autosomal recessive retinitis pigmentosa, 8 pedigrees with autosomal | Jiahui Xia Huali Zhang Dongsheng Tang Xixiang Tang Heping Dai Qian Pan Zhigao Long Xiaodong Liao | 2000 | Chinese Science Bulletin2000，45，23： | 2 |
| 16 | High carbon dioxide and low oxygen storage effects on reactive oxygen species metabolism in Pleurotus eryngii显示文摘 | Pengxia Li Xuan Zhang Huali Hu Ya Sun Yuning Wang Yancun Zhao | 2013 | Postharvest Biology and Technology2013，，： | 1 |
| 17 | Liposome formulated with TAT-modified cholesterol for enhancing the brain delivery显示文摘 | Yao Qin Huali Chen Wenmin Yuan Rui Kuai Qianyu Zhang Fulan Xie Li Zhang Zhirong Zhang Ji Liu Qin He | 2011 | International Journal of Pharmaceutics2011，，1： | 1 |
| 18 | Unitary Space Vector Quantization Codebook Design for Precoding MIMO System显示文摘 | Wu Ping Li Huali Zhang Ping | | 0，，09： | 1 |
| 19 | STAT3 ameliorates truncated tau-induced cognitive deficits显示文摘Proteolytic cleavage of tau by asparagine endopeptidase(AEP)creates tau-N368 fragments,which may drive the pathophysiology associated with synaptic dysfunction and memory deterioration in the brain of Alzheimer’s disease patients.Nonetheless,the molecular mechanisms of truncated tau-induced cognitive deficits remain unclear.Evidence suggests that signal transduction and activator of transcription-3(STAT3)is associated with modulating synaptic plasticity,cell apoptosis,and cognitive function.Using luciferase reporter assays,electrophoretic mobility shift assays,western blotting,and immunofluorescence,we found that human tau-N368 accumulation inhibited STAT3 activity by suppressing STAT3 translocation into the nucleus.Overexpression of STAT3 improved tau-N368-induced synaptic deficits and reduced neuronal loss,thereby improving the cognitive deficits in tau-N368 mice.Moreover,in tau-N368 mice,activation of STAT3 increased N-methyl-D-aspartic acid receptor levels,decreased Bcl-2 levels,reversed synaptic damage and neuronal loss,and thereby alleviated cognitive deficits caused by tau-N368.Taken together,STAT3 plays a critical role in truncated tau-related neuropathological changes.This indicates a new mechanism behind the effect of tau-N368 on synapses and memory deficits.STAT3 can be used as a new molecular target to treat tau-N368-induced protein pathology. | Bingge Zhang Huali Wan Maimaitijiang Maierwufu Qian Liu Ting Li Ye He Xin Wang Gongping Liu Xiaoyue Hong Qiong Feng | 2024 | Neural Regeneration Research2024，19，4： | 1 |
| 20 | Context-Aware Recommendation System using Graph-based Behaviours Analysis显示文摘Recommendation systems have been extensively studied over the last decade in various domains. It has been considered a powerful tool for assisting business owners in promoting sales and helping users with decision-making when given numerous choices. In this paper, we propose a novel Graph-based Context-Aware Recommendation Systems with Knowledge Graph to analyse and predict users’ behaviours, i.e., making recommendations based on historical events and their implicit associations. The model incorporates contextual information extracted from both users’ historical behaviours and events relations, where the contexts have been modelled as knowledge graphs. By leveraging the advantages offered from the knowledge graph, events dependencies and their subtle relations can be established and have been introduced in the recommendation process. Experimental results indicate that the proposed approach can outperform the state-of-the-art algorithms and achieve more accurate recommendations. | Lan Zhang Xiang Li Weihua Li Huali Zhou Quan Bai | 2021 | Journal of Systems Science and Systems Engineering2021，30，4： | 1 |
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