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| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | A Review on Metal-Organic Framework-Derived Porous Carbon-Based Novel Microwave Absorption Materials显示文摘The development of microwave absorption materials(MAMs) is a considerable important topic because our living space is crowed with electromagnetic wave which threatens human’s health.And MAMs are also used in radar stealth for protecting the weapons from being detected.Many nanomaterials were studied as MAMs,but not all of them have the satisfactory performance.Recently,metal-organic frameworks(MOFs) have attracted tremendous attention owing to their tunable chemical structures,diverse properties,large specific surface area and uniform pore distribution.MOF can transform to porous carbon(PC) which is decorated with metal species at appropriate pyrolysis temperature.However,the loss mechanism of pure MOF-derived PC is often relatively simple.In order to further improve the MA performance,the MOFs coupled with other loss materials are a widely studied method.In this review,we summarize the theories of MA,the progress of different MOF-derived PC-based MAMs,tunable chemical structures incorporated with dielectric loss or magnetic loss materials.The different MA performance and mechanisms are discussed in detail.Finally,the shortcomings,challenges and perspectives of MOF-derived PC-based MAMs are also presented.We hope this review could provide a new insight to design and fabricate MOF-derived PC-based MAMs with better fundamental understanding and practical application. | Zhiwei Zhang Zhihao Cai Ziyuan Wang Yaling Peng Lun Xia Suping Ma Zhanzhao Yin Yi Huang | 2021 | Nano-Micro Letters2021，13，4： | 17 |
| 3 | The application of geostatistics in grain size trend analysis: A case study of eastern Beibu Gulf显示文摘有 71 件表面沉积样品,从东方 Beibu 海湾收集。片刻参数(即吝啬的尺寸,排序并且偏斜度) 在使用谷物尺寸分析以后被获得。geostatistical 分析然后被使用为这些参数学习空间自相关;当时范围,在 semivariogram 的一个参数米空间自相关的规模,被估计。结果显示为排序系数的范围身体上是有意义的。从谷物尺寸趋势分析模型计算的趋势向量根据以前的研究与年度海洋发行量模式和沉积运输率一致。因此,从吝啬的尺寸的 semivariogram 导出的范围能在谷物尺寸趋势分析被用作典型距离,它可以移开基于经验或严峻的方法得到典型距离的传统的方法引起的偏爱。因此从分析能也在未来为沉积采样密度的决心为有用信息提供的 geostatistical 的结果回答工作。 | MA Fei WANG Yaping LI Yan YE Changjiang XU Zhiwei ZHANG Fan | 2010 | Journal of Geographical Sciences2010，20，1： | 14 |
| 4 | PARylation regulates stress granule dynamics, phase separation, and neurotoxicity of disease-related RNA-binding proteins显示文摘Mutations in RNA-binding proteins (RBPs) localized in ribonucleoprotein (RNP) granules, such as hnRNP A1 and TDP-43, promote aberrant protein aggregation, which is a pathological hallmark of various neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Protein posttranslational modifications (PTMs) are known to 佗gulate RNP granules. In this study, we investigate the function of poly(ADP-ribosyl)ation (PARylation), an important PTM involved in DNA damage repair and cell death, in RNP granule-related neurodegeneration. We reveal that PARylation levels are a major regulator of the assembly-disassembly dynamics of RNP granules containing disease-related RBPs, hnRNP A1 and TDP-43. We find that hnRNP A1 can both be PARylated and bind to PARylated proteins or poly(ADP-ribose)(PAR). We further uncover that PARylation of hnRNP A1 at K298 controls its nucleocytoplasmic transport, whereas PAR-binding via the PAR-binding motif (PBM) of hnRNP Al regulates its association with stress granules. Moreover, we reveal that PAR not only dramatically enhances the liquid-liquid phase separation of hnRNP A1, but also promotes the co-phase separation of hnRNP A1 and TDP-43 in vitro and their interaction in vivo. Finally, both genetic and pharmacological inhibition of PARP mitigates hnRNP Al- and TDP-43-mediated neurotoxicity in cell and Drosophila models of ALS. Together, our findings suggest a novel and crucial role for PARylation in regulating the dynamics of RNP granules, and that dysregulation in PARylation and PAR levels may con tribute to ALS disease pathoge nesis by promoting protei n aggregation. | Yongjia Duan Aiying Du Jinge Gu Gang Duan Chen Wang Xinrui Gui Zhiwei Ma Beituo Qian Xue Deng Kai Zhang Le Sun Kuili Tian Yaoyang Zhang Hong Jiang Cong Liu Yanshan Fang | 2019 | Cell Research2019，29，3： | 13 |
| 5 | New radiocarbon and archaeobotanical evidence reveal the timing and route of southward dispersal of rice farming in south China显示文摘The origins and spreads of rice agriculture have been enduring topics, yet the timing and southward dispersal from the Yangtze River Basin have been difficult to trace, due to the scarcity of archaeobotanical data, especially systematic macro-plant remains examination, combined with the poor preservation in the humid climate and acidic soils of China's southern provinces.Here, we report new radiocarbon dating and preserved rice phytolith evidence, derived from three Late Neolithic archaeological sites in south China, dated about 5,000–4,100 cal a BP.Our results demonstrate that rice farming had spread southward through the mountainous regions of Wuyi and Nanling, then entered the areas of Western Fujian and North Guangdong by 5,000 cal a BP, followed by continued expansion into coastal areas of East China Sea and South China Sea, also crossing the Taiwan Strait, around 4,500–4,000 cal a BP.The North River,East River, Min River, and possibly other river systems likely were influential as pathways or conduits. | Xiaoyan Yang Qiuhe Chen Yongchao Ma Zhao Li Hsiao-chun Hung Qianglu Zhang Zhiwei Jin Suoqiang Liu Zhenyu Zhou Xianguo Fu | 2018 | Science Bulletin2018，63，22： | 9 |
| 6 | Advances in luminescent lanthanide complexes and applications显示文摘Luminescent lanthanide complexes have been widely investigated as light emitting materials in bio-imaging and sensing, solid state lighting and display, anti-fake tags and light conversion films, due to their characterized photophysical properties including large Stokes shift, long lifetime, and sharp emission spectrum, arising from the sensitized f-f transitions. In this review, we summarize the most recent advances in luminescent lanthanide complexes and their applications from 2015 to August 2017 concerning of general concepts to potential applications. We first introduce the basic concept of sensitized luminescence of lanthanide complexes and the strategies used for highly luminescent complexes. Then recent varieties of luminescent lanthanide complexes and their hybrid materials are presented. Finally, applications are discussed in detail. | WEI Chen MA Li WEI HuiBo LIU ZhiWei BIAN ZuQiang HUANG ChunHui | 2018 | Science China(Technological Sciences)2018，61，9： | 8 |
| 7 | Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction显示文摘 | Xiao-E Jia Ke Ma Tao Xu Lei Gao Shuang Wu Cong Fu Wenjuan Zhang Zhizhang Wang Kaiyu Liu Mei Dong Changbin Jing Chunguang Ren Zhiwei Dong Yi Chen Yi Jin Qiuhua Huang Xing Chang Min Deng Li Li Lingfei Luo Jun Zhu Yongjun Dang Hung-Chun Chang Leonard I Zon Yi Zhou Saijuan Chen Weijun Pan | 2015 | Cell Research2015，25，8： | 8 |
| 8 | A Scenario-Based Evaluation of COVID-19-Related Essential Clinical Resource Demands in China显示文摘The coronavirus disease 2019(COVID-19)pandemic is a global crisis,and medical systems in many countries are overwhelmed with supply shortages and increasing demands to treat patients due to the surge in cases and severe illnesses.This study aimed to assess COVID-19-related essential clinical resource demands in China,based on different scenarios involving COVID-19 spreads and interventions.We used a susceptible–exposed–infectious–hospitalized/isolated–removed(SEIHR)transmission dynamics model to estimate the number of COVID-19 infections and hospitalizations with corresponding essential healthcare resources needed.We found that,under strict non-pharmaceutical interventions(NPIs)or mass vaccination of the population,China would be able to contain community transmission and local outbreaks rapidly.However,under scenarios involving a low intensity of implemented NPIs and a small proportion of the population vaccinated,the use of a peacetime–wartime transition model would be needed for medical source stockpiles and preparations to ensure a normal functioning healthcare system.The implementation of COVID-19 vaccines and NPIs in different periods can influence the transmission of COVID-19 and subsequently affect the demand for clinical diagnosis and treatment.An increased proportion of asymptomatic infections in simulations will not reduce the demand for medical resources;however,attention must be paid to the increasing difficulty in containing COVID-19 transmission due to asymptomatic cases.This study provides evidence for emergency preparations and the adjustment of prevention and control strategies during the COVID-19 pandemic.It also provides guidance for essential healthcare investment and resource allocation. | Ting Zhang Qing Wang Zhiwei Leng Yuan Yang Jin Yang Fangyuan Chen Mengmeng Jia Xingxing Zhang Weiran Qi Yunshao Xu Siya Chen Peixi Dai Libing Ma Luzhao Feng Weizhong Yang | 2021 | Engineering2021，7，7： | 7 |
| 9 | Cloning and bioinformatics analysis of a full-length cDNA of porcine CRl-like gene显示文摘 | Jing Cheng Junbing Jiang Junxing Zhao Zhirui Wang Yaogui Sun Haili Ma Kuohai Fan Wei Yin Na Sun Zhiwei Wang Xin Zhao Hongquan Li | 2014 | Acta Biochimica et Biophysica Sinica2014，46，11： | 7 |
| 10 | Desulfurization kinetics of ZnO sorbent loaded on semi-coke support for hot coal gas显示文摘Zn-based sorbent (Z20SC) prepared through semi-coke support in 20 wt% zinc nitrate solution by high-pressure impregnation presents an excellent desulfurization capacity in hot coal gas,in which H2 S can not be nearly detected in the outlet gas before 20 h breakthrough time.The effects of the main operational conditions and the particle size of Z20SC sorbent on its desulfurization performances sorbent were investigated in a fixed-bed reactor and the desulfurization kinetics of Z20SC sorbent removing H2 S from hot coal gas was calculated based on experimental data.Results showed that the conversion of Z20SC sorbent desulfurization reaction increased with the decrease of the particle size of the sorbent and the increases of gas volumetric flow rate,reaction temperature and H 2 S content in inlet gas.Z20SC sorbent obtained from hydrothermal synthesis by high-pressure impregnation possessed much larger surface area and pore volume than semi-coke support,and they were significantly reduced after the desulfurization reaction.The equivalent grain model was reasonably used to analyze experimental data,in which k s=4.382×10-3 exp(-8.270×103/RgT) and Dep=1.262×10-4exp(1.522×104/RgT).It suggests that the desulfurization reaction of the Z20SC sorbent is mainly controlled by the chemical reaction in the initial stage and later by the diffusion through the reacted sorbent layer. | Zhiwei Ma Xianrong Zheng Liping Chang Ruiyuan He Weiren Bao | 2012 | Journal of Natural Gas Chemistry2012，21，5： | 7 |
| 11 | Complete three-dimensional coseismic displacements due to the 2021 Maduo earthquake in Qinghai Province,China from Sentinel-1 and ALOS-2 SAR images显示文摘On 22 nd May 2021(local time),an earthquake of M_(s)7.4 struck Maduo county in Qinghai Province,China.This was the largest earthquake in China since the 2008 Wenchuan earthquake.In this study,ascending/descending Sentinel-1 and advanced land observation satellite-2(ALOS-2)synthetic aperture radar(SAR)images were used to derive the three-dimensional(3-D)coseismic displacements of this earthquake.We used the differential interferometric SAR(In SAR,DIn SAR),pixel offset-tracking(POT),multiple aperture In SAR(MAI),and burst overlap interferometry(BOI)methods to derive the displacement observations along the line-of-sight(LOS)and azimuth directions.To accurately mitigate the effect of ionospheric delay on the ALOS-2 DIn SAR observations,a polynomial fitting method was proposed to optimize range-spectrum-split-derived ionospheric phases.In addition,the 3-D displacement field was obtained by a strain model and variance component estimation(SM-VCE)method based on the high-quality SAR displacement observations.Results indicated that a left-lateral fault slip with the largest horizontal displacement of up to 2.4 m dominated this earthquake,and the small-magnitude vertical displacement with an alternating uplift/subsidence pattern along the fault trace was more concentrated in the near-fault regions.Comparison with the global navigation satellite system data indicated that the SM-VCE method can significantly improve the accuracy of the displacements compared to the classical weighted least squares method,and the incorporation of the BOI displacements can substantially benefit the accuracy of north-south displacement.In addition to the displacements,three coseismic strain invariants calculated based on the strain model parameters were also investigated.It was found that the eastern and western parts of the faults suffered more significant strains compared with the epicenter region. | Jihong LIU Jun HU Zhiwei LI Zhangfeng MA Lixin WU Weiping JIANG Guangcai FENG Jianjun ZHU | 2022 | Science China Earth Sciences2022，65，4： | 6 |
| 12 | A 5th order monotonicity-preserving upwind compact difference scheme显示文摘Based on an upwind compact difference scheme and the idea of monotonicity-preserving, a 5th order monotonicity-preserving upwind compact difference scheme (m-UCD5) is proposed. The new difference scheme not only retains the advantage of good resolution of high wave number but also avoids the Gibbs phenomenon of the original upwind compact difference scheme. Compared with the classical 5th order WENO difference scheme, the new difference scheme is simpler and small in diffusion and computation load. By employing the component-wise and characteristic-wise methods, two forms of the new difference scheme are proposed to solve the N-S/Euler equation. Through the Sod problem, the Shu-Osher problem and the two-dimensional Double Mach Reflection problem, numerical solutions have demonstrated this new scheme does have a good resolution of high wave number and a robust ability of capturing shock waves, leading to a conclusion that the new difference scheme may be used to simulate complex flows containing shock waves. | HE ZhiWei LI XinLiang FU DeXun MA YanWen | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，3： | 6 |
| 13 | Chromosome-level genome of Himalayan yew provides insights into the origin and evolution of the paclitaxel biosynthetic pathway显示文摘Taxus,commonly known as yew,is a well-known gymnosperm with great ornamental and medicinal value.In this study,by assembling a chromosome-level genome of the Himalayan yew(Taxus wallichiana)with 10.9 Gb in 12 chromosomes,we revealed that tandem duplication acts as the driving force of gene family evolution in the yew genome,resulting in the main genes for paclitaxel biosynthesis,i.e.those encoding the taxadiene synthase,P450s,and transferases,being clustered on the same chromosome.The tandem duplication may also provide genetic resources for the nature to sculpt the core structure of taxoids at different positions and subsequently establish the complex pathway of paclitaxel by neofunctionalization.Furthermore,we confirmed that there are two genes in the cluster encoding isoenzymes of a known enzyme in the paclitaxel biosynthetic pathway.The reference genome of the Himalayan yew will serve as a platform for decoding the complete biosynthetic pathway of paclitaxel and understanding the chemodi-versity of taxoids in gymnosperms. | Jian Cheng Xiao Wang Xiaonan Liu Xiaoxi Zhu Zihe Li Huanyu Chu Qian Wang QianQian Lou Bijun Cai Yiqun Yang Xiaoyun Lu Kai Peng Dingyu Liu Yuwan Liu Lina Lu Huan Liu Ting Yang Qijin Ge Chengcheng Shi Guichun Liu Zhiwei Dong Xun Xu Wen Wang Huifeng Jiang Yanhe Ma | 2021 | Molecular Plant2021，14，7： | 6 |
| 14 | MicroRNA expression profile of gastric cancer stem cells in the MKN-45 cancer cell line显示文摘MicroRNAs (miRNAs ) 玩在目标送信人 RNA 的 post-transcriptional 基因 silencing 的重要角色,它几乎涉及所有生物过程。以前,我们证明了从 MKN-45 癌症房间的形成身体的房间衬里的球状体拥有了胃的癌症干细胞(CSC ) 性质。在这研究,我们试图决定胃的 CSC 的 miRNA 侧面并且在胃的 CSC 探索 miRNAs 的角色。人的 miRNA microarrays,它包含为 1887 人的 miRNAs 特定的探针被用来决定胃的 CSC 的表示侧面。有一个超过 2 褶层变化的 182 miRNAs 的一个总数被识别是在球状体之间表示的差别形成身体的房间和父母房间。这些 miRNAs, 9 miRNAs 在球状体是过去表示的形成身体的房间当另外的 173 miRNAs 都是下面表示的时,显示在人的胃的 CSC 的大多数 miRNAs 的角色可以是肿瘤 suppressors。microarray 分析的结果被量的即时聚合酶链反应验证,并且坚固性率是 70%(7 从 10 ) 。为验证 miRNAs 的目标基因被使用三个联机软件程序预言,人权保护, PicTar,和 TargetScan。大多数 miRNAs 的潜在的目标与在癌症的肌动朊细胞骨架,焦点的粘附,细胞外的 matrixreceptor 相互作用,和小径的规定相关。特别,几基因与干细胞基因的一些枢轴的发信号小径被联系。评估胃的 CSC 的典型 miRNAs 可以是为学习胃的癌症并且开发治疗学的策略的一个新方法,它在胃的癌症在根除瞄准了 CSC 的 subpopulation。 | Jianming Liu Lilin Ma Zhiwei Wang Lei Wang Chun Liu Ruixin Chen Jianguo Zhang | 2014 | Acta Biochimica et Biophysica Sinica2014，46，2： | 6 |
| 15 | Convective high-speed flow and field-aligned high-speed flows explored by TC-1显示文摘From June 1, 2004 to October 31, 2006, a total 465 high-speed flow events are observed by the TC-1 satellite in the near-Earth region (?13 RE < x < ?9 RE, |Y |<10 RE, |Z|<5 RE). Based on the angle between the flow and the magnetic field, the high-speed flow events are further divided into two types, that is, field-aligned high-speed flow (FAHF) in the plasma sheet boundary and convective bursty bulk flow (BBF) in the center plasma sheet. Among the total 465 high-speed flow events, there are 371 FAHFs, and 94 BBFs. The CHF are mainly concentrated in the plasma sheet, the intersection angle between the flow and the magnetic field is larger, the magnetic field intensity is relatively weak. The FHF are mainly distributed near the boundary layer of the plasma sheet, the intersection angle between the flow and magnetic field is smaller, and the magnetic field intensity is relatively strong. The convective BBFs have an important effect on the substorm. | ZHANG LingQian LIU ZhenXing MA ZhiWei W. BAUMJOHANN M.W. DUNLOP WANG GuangJun WANG Xiao H. REME C. CARR | 2008 | Chinese Science Bulletin2008，53，15： | 5 |
| 16 | Bevacizumab biosimilar LY01008 compared with bevacizumab(Avastin)as first-line treatment for Chinese patients with unresectable,metastatic,or recurrent non-squamous non-small-cell lung cancer:A multicenter,randomized,double-blinded,phase Ⅲ trial显示文摘Background:Previous studies have demonstrated the preclinical pharmacological and toxicological consistency,and clinical pharmacokinetic equivalence of bevacizumab biosimilar LY01008 with reference bevacizumab(Avastin).This randomized controlled trial aimed to compare the efficacy and safety of LY01008 with Avastin in first-line treatment of Chinese patients with advanced or recurrent non-squamous non-small cell lung cancer(NSCLC).Methods:StageⅢB-ⅣNSCLC patients with evaluable lesions,good physical status,and adequate organ functions from 67 centers across China were randomized in a ratio of 1:1 to receive LY01008 or Avastin 15 mg/kg intravenously in combination with paclitaxel/carboplatin(combined treatment)for 4-6 cycles,followed by maintenance monotherapy with LY01008 until disease progression,intolerable toxicity,or death.The primary endpoint was objective response rate(ORR)in accordance with Response Evaluation Criteria in Solid Tumors(RECIST)version 1.1 confirmed by independent radiological review committees(IRRC).Secondary endpoints included disease control rate(DCR),duration of response(DoR),progression-free survival(PFS),overall survival(OS),and safety.This study was registered in Clinical Trials.gov(NCT03533127).Results:Between December 15^(th),2017,and May 15^(th),2019,a total of 649 patients were randomized to the LY01008(n=324)or Avastin(n=325)group.As of September 25th,2019 for primary endpoint analysis,589 patients received ORR evaluation,with a median number of combined treatment cycles of 5(range 1-6)andmedian duration of treatment of 3.0(range 0.0-5.1)months.ORRof responseevaluable patients in the LY01008 and Avastin groups were 48.5% and 53.0%,respectively.The stratified ORR ratio was 0.91(90%CI 0.80-1.04,within the prespecified equivalence margin of 0.75-1.33).Up to May 15^(th),2020,with a median follow-up of 13.6(range 0.8-28.4)months,no notable differences in DCR,median DoR,median PFS,median OS,and 1-year OS rate were observed between the LY01008 and Avastin groups.There were no clinically meaningful differences in safety and immunogenicity across treatment groups.Conclusions:LY01008 demonstrated similarity to Avastin in terms of efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC.LY01008 combined with paclitaxel/carboplatin is expected to become a new treatment option for unresectable,metastatic,LY01008 and Avastin groups.There were no clinically meaningful differences in safety and immunogenicity across treatment groups.Conclusions:LY01008 demonstrated similarity to Avastin in terms of efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC.LY01008 combined with paclitaxel/carboplatin is expected to become a new treatment option for unresectable,metastatic,or recurrent non-squamous NSCLC patients in the first-line setting. | Yuankai Shi Kaijian Lei Yuming Jia Bingqiang Ni Zhiyong He Minghong Bi Xicheng Wang Jianhua Shi Ming Zhou Qian Sun Guolei Wang Dongji Chen Yongqian Shu Lianke Liu Zhongliang Guo Yong Liu Junquan Yang Ke Wang Ke Xiao LinWu Tienan Yi Debin Sun Mafei Kang Tianjiang Ma Yimin Mao Jinsheng Shi Tiegang Tang Yan Wang Puyuan Xing Dongqing Lv Wangjun Liao Zhiguo Luo Bin Wang Xiaohong Wu Xiaoli Zhu Shuhua Han Qisen Guo Rongyu Liu Zhiwei Lu Jianyong Zhang Jian Fang Changlu Hu Yinghua Ji Guolong Liu Hong Lu Dedong Wu Junhong Zhang Shuyang Zhu Zheng Liu Wensheng Qiu Feng Ye Yan Yu Yanqiu Zhao Qinhong Zheng Jun Chen Zhanyu Pan Yiping Zhang Wenjuan Lian Bo Jiang Bo Qiu Guojun Zhang Hua Zhang Yanju Chen Yuan Chen Hongbing Duan Manxiang Li Shengming Liu Lijun Ma Hongming Pan Xia Yuan Xueli Yuan Yulong Zheng Emei Gao Li Zhao Shumin Wang Can Wu | 2021 | Cancer Communications2021，41，9： | 5 |
| 17 | Roles of initial current carrier in the distribution of field-aligned current in 3-D Hall MHD simulations显示文摘A three-dimensional (3-D) Hall MHD simulation is carried out to study the roles of initial current carrier in the topology of magnetic field, the generation and distribu- tion of field aligned currents (FACs), and the appearance of Alfvén waves. Consid- ering the contribution of ions to the initial current, the topology of the obtained magnetic field turns to be more complex. In some cases, it is found that not only the traditional By quadrupole structure but also a reversal By quadrupole structure appears in the simulation box. This can explain the observational features near the diffusion region, which are inconsistent with the Hall MHD theory with the total ini- tial current carried by electrons. Several other interesting features are also emerged. First, motions of electrons and ions are decoupled from each other in the small plasma region (Hall effect region) with a scale less than or comparable with the ion inertial length or ion skin depth di=c/ωp. In the non-Hall effect region, the global magnetic structure is shifted in +y direction under the influence of ions with initial y directional motion. However, in the Hall effect region, magnetic field lines are bent in ?y direction, mainly controlled by the motion of electrons, then By is generated. Second, FACs emerge as a result of the appearance of By. Compared with the prior Hall MHD simulation results, the generated FACs shift in +y direction, and hence the dawn-dusk symmetry is broken. Third, the Walén relation in our simulations is consistent with the Walén relation in Hall plasma, thus the presence of Alfvén wave is confirmed. | ZHANG XianGuo PU ZuYin MA ZhiWei ZHOU XuZhi | 2008 | Science China(Technological Sciences)2008，51，3： | 4 |
| 18 | Synthesis of polycrystalline γ-AlON powders by novel wet chemical processing显示文摘The synthesis of polycrystalline aluminum oxynitride (AlON) powders was investigated by the carbothermal reduction and nitridation (CRN) of amorphous precursor obtained by wet chemical processing. Co-precipitation processing was employed to achieve amorphous precursor from Al(NO3)3 solution dispersed by nanosized carbon particles, which was composed of Al(OH)3 and C particles homogeneously. The effects of the content of carbon black, pH value, and calcination temperature on formation of AlON phase were investigated by means of XRD, SEM and TEM, respectively. It was found that single phase AlON powder could be synthesized when the resultant precursors were calcined at 1750°C for 2 hours under flowing N2 . Under optimal additional content of C (5.6wt%), the resultant AlON powders exhibited the primary particle size of about 1-3 μm with a specific surface area of 3.2m2/g, which were superior to that of carbothermal reduction of immediate mixture of γ-Al2O3/C powders. | LEI JingXuan MA FeiZhong SHI Ying XIE JianJun HU Wei SHI ZhiWei | 2012 | Science China(Technological Sciences)2012，55，12： | 4 |
| 19 | Recent studies in satellite observations of three-dimensional magnetic reconnection显示文摘Magnetic reconnection is a main process converting the magnetic energy into thermal and kinetic energy in plasmas. It is one of the fundamental problems of crucial importance not only to space plasmas physics and space weather studies,such as the solar flare,coronal mass ejections and magnetospheric substorms,but also to the stability analysis in magnetically confined fusion. In general,except for cases with periodical boundary conditions,three-dimensional(3D) magnetic re-connection occurs on magnetic separatrices generated by magnetic nulls. Here we briefly introduce/review the theories and some recent satellite observations of 3D magnetic reconnection. Topics to be further studied are also discussed. | XIAO ChiJie WANG XiaoGang PU ZuYin MA ZhiWei ZHAO Hui ZHOU GuiPing WANG JingXiu LIU ZhenXing | 2007 | Science China(Technological Sciences)2007，50，3： | 4 |
| 20 | Subtyping of type A influenza by sequencing the variable regions of HA gene specifically amplified with RT-PCR显示文摘The outbreak of a novel influenza A(H1N1) virus across the globe poses a threat to human health.It is of paramount importance to develop a rapid,reliable and inexpensive diagnostic procedure.Based on the bioinformatic information from public database,primers specific for influenza A virus surface protein haemagglutinin(HA) of several subtypes(including H1,H2,H3,H5,H7 and H9) were designed.Primer-specific PCR products were subjected to sequencing for accurately distinguishing H1 and H3 subtypes from others.This sequencing-based detection method will not only be applied to rapid detection and simultaneous subtype identification of new influenza A virus H1N1,but also provide the strategies to monitor other new types ofinfluenza virus with explosive potential. | YAN An DING GuoHui ZHOU ZhenFeng DONG Hui ZHANG YaKun ZHU Lei HE YunGang ZHANG GuoQing LI YiXue SUN Bing HUANG Zhong LAN Ke JIN Li WANG HongYan WANG XiaoNing YANG Zhong ZHONG Yang DAI JianXin GUO YaJun WANG Hao CHE XiaoYan WU Fan YUAN ZhenGan ZHANG Xi CAO ZhiWei ZHOU XiaoNong ZHOU JiaHai MA ZhiYong TONG GuangZhi ZHAO GuoPing JIN WeiRong XIONG Hui | 2009 | Chinese Science Bulletin2009，54，13： | 3 |
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