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| 1 | Clinical scenarios for the use of S100β as a marker of hepatic encephalopathy显示文摘AIM: To evaluate the association between serum concentrations of S100β in patients with cirrhosis and the presence of low grade hepatic encephalopathy(HE).METHODS: This was a cross-sectional study. The population was categorized into four groups healthy subjects, cirrhosis without HE, cirrhosis with covert hepatic encephalopathy(CHE) and cirrhosis with overt HE. Kruskal-Wallis, Mann Whitney's U with Bonferroni adjustment Spearman correlations and area under the ROC were used as appropriate.RESULTS: A total of 61 subjects were included, 46 cirrhotic patients and 15 healthy volunteers. S100β values were different among all groups, and differences remained significant between groups 1 and 2(P < 0.001), and also between groups 2 and 3(P = 0.016), but not between groups 3 and 4. In cirrhotic patients with HE S100β was higher than in patients without HE [0.18(0.14-0.28) ng/m L vs 0.11(0.06-0.14) ng/m L, P < 0.001]. There was a close correlation between serum concentrations of S100β and psychometric hepatic encephalopathy score in patients with cirrhosis without HE compared to the patients with cirrhosis with CHE(r =-0.413, P = 0.019). ROC curve analysis yielded > 0.13 ng/m L as the best cutoff value of S100β for the diagnosis of HE(sensitivity 83.3%, specificity 63.6%).CONCLUSION: Serum concentrations of S100β are higher in patients with cirrhosis than in healthy volunteers, and are further increased in the presence of hepatic encephalopathy. The results suggest that serum biomarkers such as S100β could help in the correct characterization of incipient stages of HE. | Andrés Duarte-Rojo Astrid Ruiz-Margáin Ricardo U Macias-Rodriguez Francisco Javier Cubero José Estradas-Trujillo Rosa Ma Munoz-Fuentes Aldo Torre | 2016 | World Journal of Gastroenterology2016,22,17: | 4 |
| 2 | Immunological effect of aqueous extract of Vernonia amygdalina and a known immune booster called immunace and their admixtures on HIV/AIDS clients:a comparative study显示文摘Objective:To investigate the immunological effect of Vernonia amygdalina(V.amygdalina) leaf extract and immunace on HIV infected patients taking highly active antiretrwiral therapy. Methods:Fresh V.amygdalina leaves were collected within Nsukka area in Enugu State.The leaves were rinsed with distilled water.Two handful of cleaned fresh leaves were soaked in 200 mL water and squeezed gently by hand to a mixture.Clients were divided into four groups and each group was given different combination.They took the medication for four weeks.The immune effect was tested against marketed immune booster in some retroviral clients.Results:The mean absolute CD4 count was increased in the client who took the extract or supplement.And the clients who took both the extract and supplement had a greater increase in the CD4 count.The increased CD4 was significant as compared with the control group(P<0.05).The skin rashes were also improved in the entire groups.Conclusions:It can be concluded that the aqueous extract of V.amygdalina and immunace or both have immunological effect on HIV infected patients. Therefore,we suggest that the V.amygdalina extract or immunace or both could be used as adjuvant in the management of HIV/AIDS clients. | Momoh MA Muhamed U Agboke AA Akpabio EI Uduma Eke Osonwa | 2012 | Asian Pacific Journal of Tropical Biomedicine2012,2,3: | 3 |
| 3 | Dynamic Programming for Multidimensional Stochastic Control Problems | Jin Ma Department of Mathematics,Purdue University,West Lafayette,IN 47907-1395,U S A E-mail:majin@math.purdue,eduJiongmin Yong Laboratory of Mathematics for Nonlinear Science,Department of Mathematics,and Institute of Mathematical Finance,Fudan University,Shanghai 200433,P.R.China E-mail:jyong@fudan,edu.cn | 1999 | Acta Mathematica Sinica,English Series1999,15,4: | 2 |
| 4 | Cytokine correlates of clinical response patterns to infliximab treatment of ankylosing spondylitis显示文摘 | Stone MA Payne U Pacheco-Tena C | 2004 | Ann Rheum Dis2004,63,1: | 2 |
| 5 | Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite显示文摘As China’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band(1-250 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3 Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be reconstructed.Here we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results. | Shuang-Nan Zhang TiPei Li FangJun Lu LiMing Song YuPeng X u CongZhan Liu Yong Chen XueLei Cao QingCui Bu Zhi Chang Gang Chen Li Chen TianXiang Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong Yuan Yuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan Can Gungor ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge Ou JinLu Qu Na Sai RenCheng Shang GuoHong Shen Liang Sun Ying Tan Lian Tao YouLi Tuo Chen Wang ChunQin Wang GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BaiYang Wu BoBing Wu Mei Wu GuangCheng Xiao ShaoLin Xiong LinLi Yan JiaWei Yang Sheng Yang YanJi Yang QiBin Yi Bin Yuan AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang ShenYi Zhangs Shu Zhang Tong Zhang WanChang Zhang Wei Zhang WenZhao Zhang Yi Zhang YiFei Zhang YongJie Zhang Yue Zhang Zhao Zhang Zhi Zhang ZiLiang Zhang HaiSheng Zhao XiaoFan Zhao ShiJie Zheng JianFeng Zhou YuXuan Zhu Yue Zhu RenLin Zhuang | 2020 | Science China(Physics,Mechanics & Astronomy)2020,63,4: | 2 |
| 6 | DNA-PK, the DNA-activated protein kinase, is differentially expressed in normal and malignant human tissues显示文摘 | Moll U Lau R Sypes MA | 1999 | Oncogene1999,18,20: | 1 |
| 7 | Complement: a novel factor in basal and ischemia-induced neurogenesis显示文摘 | Rahpeymai Y Hietala MA Wilhelmsson U | 2006 | EMBO J2006,25,6: | 1 |
| 8 | Improvement of health-related quality of life in breast cancer patients by inpatient rehabilitation显示文摘 | Hartmann U Ring C Reuss-Borst MA | 2004 | Med Klin ( Munieh)2004,99,: | 1 |
| 9 | Bone marrow edema : p- athophysiology, differential diagnosis, and imaging 显示文摘 | Start AM Wessely MA Albastaki U | 2008 | Acta Radi- ol2008,49,7: | 1 |
| 10 | New bone formation with teriparatideis not retarded by long-term pretreatment with alendronate,estrogen,or raloxifene in ovariectomized rats显示文摘 | Bryant H U Zeng Q | 2003 | Endocrinology2003,144,5: | 1 |
| 11 | Catheter based in vivo imaging of enzyme activity and gene expression:feasibility study in mice显示文摘 | Funovics MA Weissleder R Mahmood U | 2004 | Radiology2004,231,3: | 1 |
| 12 | Bone marrow edema:pathophysiology,differential diagnosis,and imaging显示文摘 | Starr AM Wessely MA Albastaki U | | 0,,07: | 1 |
| 13 | Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study 显示文摘 | Kumarasamy KK Toleman MA Walsh TR Bagaria J Butt F Balakrishnan R Chaudhary U Doumith M Giske CG Irfan S Krishnan P Kumar AV Maharjan S Mushtaq S Noorie T Paterson DL Pearson A Perry C Pike R Rao B Ray U Sarma JB Sharma M Sheridan E Thirunarayan MA Turton J Upadhyay S Warner M Welfare W Livermore DM Woodford N | 2010 | Lancet Infect Dis2010,10,9: | 1 |
| 14 | The choice of anesthetic maintenancetechnique influences the antiinflammatory cytokine response to abdominal suryery 显示文摘 | Gilliland HE Armstrong MA Garabine U | 1997 | Anesth Analy1997,85,: | 1 |
| 15 | Fludarabine, mitoxantrone and dexamethasone in the treatment of indolent B - and T - cell lymphoid malignancies in chinese patients 显示文摘 | MA S Y A U W Y CHIM C S | 2004 | Br J Haematal2004,124,: | 1 |
| 16 | Degradation of ginsenosides in humans after oral administration 显示文摘 | Tawab MA Bahr U Karas M | 2003 | Drug Metab Dispos2003,31,8: | 1 |
| 17 | Decreasing unpalatable flavo-noid components in Citrus:the effect of transformation construct显示文摘 | Koca U Berhow MA Febres VJ | 2009 | Physiologia Plantarum2009,137,2: | 1 |
| 18 | Assess- ing cancer risk in china from ',/- Hexachlorocyclohexane emitted from Chinese and Indian sources 显示文摘 | X U Yue TIAN Chongguo MA Jianmin | 2013 | Environ- mental Science and Technology2013,47,13: | 1 |
| 19 | DNA-PK, the DNA-activated protein kinase,is differentially expressed in normal and malignant human tissues显示文摘 | Moll U Lau R Sypes MA | 1999 | Oncogene1999,8,20: | 1 |
| 20 | Five-factor personality traits in patients with seasonal depression:treatment effects and comparisons with bipolar patients显示文摘 | Blais MA Otto MW | 1999 | J Affect Disord1999,55,1: | 1 |