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| 1 | Comparison of the short-term and long-term outcomes of laparoscopic hysterectomies and of abdominal hysterectomies: a case study of 4,895 patients in the Guangxi Zhuang Autonomous Region, China显示文摘Background: To evaluate the short-term and long-term outcomes after laparoscopic hysterectomy(LH) compared with abdominal hysterectomy(AH) in case of benign gynecological disease. Methods: A multi-center cohort retrospective comparative study of population among 4,895 hysterectomies(3,539 LH vs.1,356 AH) between 2007 and 2013 was involved. Operative time(OT), estimated blood loss(EBL), intra-operative and post-operative complications, passing flatus; days with indwelling catheter, questionnaires covering pelvic floor functions and sexual functions were assessed.Results: The EBL(174.1±157.4 vs. 263.1±183.2 cc, LH and AH groups, respectively), passing flatus(38.7±14.1 vs. 48.1±13.2 hours), days with indwelling catheter(1.5±0.6 vs. 2.2±0.8 days), use of analgesics(6.5% vs. 73.1%), intra-operative complication rate(2.4% vs. 4.1%), post-operative complication rate(2.3% vs. 5.7%), post-operative constipation(12.1% vs. 24.6%), mild and serious stress urinary incontinence(SUI) post-operative(P<0.001; P=0.014), and proportion of Female Sexual Functioning Index(FSFI) total score <26.55 post-operative(P<0.001) of the LH group were significantly less than those of AH group. There wereno significant differences in OT(106.5±34.5 vs. 106.2±40.3 min) between the two groups.Conclusions: LH is a safe and efficient operation for improving patients' long-term quality of life(Qo L), and LH is a cost-effectiveness procedure for treating benign gynecological disease. LH is superior to AH due to reduced EBL, reduced post-operative pain and earlier passing flatus. | Hongying He Zhijun Yang Dingyuan Zeng Jiangtao Fan Xiaoxia Hu Yuan Ye Hua Bai YanmingJiang Zhong Lin Zhiying Lei Xinlin Li Lian Li Jinghua Gan Ying Lan Xiongzhi Tang Danxia Wang Junsong Jiang Xiaoyan Wu Meiying Li Xiaoqing Ren Xiaomin Yang Mei Liu Qinmei Wang Fuyan jiang Li Li | 2016 | Chinese Journal of Cancer Research2016，28，2： | 6 |
| 2 | Review on the development of genotyping methods for assessing farm animal diversity显示文摘Advances in molecular biotechnology have introduced new generations of molecular markers for use in the genetic improvement of farm animals. Consequently, more accurate genetic information can be obtained to better understand existing animal genetic resources. This review gives a brief summary on the development of genetic markers including both the classical genetic markers and more advanced DNA-based molecular markers. This review will help us better understand the characteristics of different genetic markers and the genetic diversity of animal genetic resources. | Wanjie Yang Xiaolong Kang Qingfeng Yang Yao Lin Meiying Fang | 2013 | Journal of Animal Science and Biotechnology2013，4，4： | 2 |
| 3 | 2021 Chinese consensus on the diagnosis and management of primary immune thrombocytopenia in pregnancy显示文摘Immune thrombocytopenia(ITP)is an acquired disease characterized by isolated thrombocytopenia,which is one of the most common causes of thrombocytopenia during pregnancy.Women with ITP who have severe thrombocytopenia are at an increased risk for life-threatening obstetric complications.Therefore,we established this consensus statement on the diagnosis and management of ITP during pregnancy(detailed information is available in the Supplementary File,http://links.lww.com7CM9/A978). | Zhang Xiaohui Chen Fangping Chen Xiequn Cheng Yunfeng Fang Meiyun Feng Jianming Fu Haixia Gao Hong Han Yue He Aili Hou Ming Hu Yu Huang Ruibin Huang Wenrong Jing Zhicheng Kong Peiyan Liang Aibin Liang Meiying Liu Daihong Liu Junling Liu Lin Liu Xiaowei Ma Liangming Mei Heng Ni Heyu Niu Ting Peng Jun Qiao Jianlin Ren Jinhai Song Yongping Tang Liang V Tong Tong Wang Shaoyuan Wang Xin Wang Zhao Wei Hui Wu Depei Wu Guangsheng Xu Caigang Xu Xue Xu Yajing Yang Linhua Yang Renchi Yang Tonghua Yin Chenghong Yu Li Zhang Guangsen Zhang Lei Zhang Liansheng Zhang Xi Zhao Weili Zhao Yongqiang Zhou Daobin Zhou Hu Zhou Zeping Zhu Tienan Wang Jianliu Huang Xiaojun | 2022 | Chinese Medical Journal2022，，8： | 2 |
| 4 | Engineered gold/black phosphorus nanoplatforms with remodeling tumor microenvironment for sonoactivated catalytic tumor theranostics显示文摘The imbalance between oxidants and antioxidants in cancer cells would evoke oxidative stress-induced cell death,which has been demonstrated to be highly effective in treating malignant tumors.Sonodynamic therapy(SDT)adopts ultrasound(US)as the excitation source to induce the production of reactive oxygen species(ROS),which emerges as a noninvasive therapeutic strategy with deep tissue penetration depth and high clinical safety.Herein,we construct novel sonoactivated oxidative stress amplification nanoplatforms by coating MnO_(2) on Au nanoparticle-anchored black phosphorus nanosheets and decorating soybean phospholipid subsequently(Au/BP@MS).The Au/BP@MS exhibit increased ROS generation efficiency under US irradiation in tumor tissues due to Au/BP nanosensitizer-induced improvement of electron-hole separation as well as MnO_(2)-mediated O_(2) generation and GSH depletion,thus leading to notable inhibition effect on tumor growth.Moreover,tumor microenvironment-responsive biodegradability of Au/BP@MS endows them with enhanced magnetic resonance imaging guidance and clinical potential for cancer theranostics. | Ting Chen Weiwei Zeng Changjun Tie Mian Yu Huisong Hao Yang Deng Qianqian Li Hairong Zheng Meiying Wu Lin Mei | 2022 | Bioactive Materials2022，7，4： | 1 |
| 5 | A new synonym of the species Falsomesosella truncatipennis Pic,1944(Coleoptera:Cerambycidae:Lamiinae:Mesosini)显示文摘The genus Falsomesosella Pic,1925 currently includes two subgenera,with 36 species/subspecies described in the nominate subgenus(Tavakilian&Chevillotte,2021).Among them,10 species were recorded from China(Lin&Tavakilian,2019).Recently,Lazarev(2021)described the 37 th species from Shaanxi Province of China.However,it was based on four specimens of Falsomesosella truncatipennis Pic,1944,herein we propose the new synonym. | Meiying Lin Andreas Weigel Siqin Ge | 2021 | Zoological Systematics2021，46，4： | 1 |
| 6 | A new species of the genus Eodorcadion Breuning from Alxa desert in Inner Mongolia, China(Coleoptera:Cerambycidae)显示文摘A new species, Eodorcadion(Ornatodorcadion) zhaoi sp. nov., is described from the Alxa desert in Inner Mongolia, China. A key to species of the subgenus Eodorcadion(Ornatodorcadion) is provided. The type specimens are deposited in IZCAS, CCXF and CMD,respectively. | Mikhail L.Danilevsky Xuefeng Chen Meiying Lin | 2019 | Zoological Systematics2019，44，2： | 0 |
| 7 | Book Review:Longhorned Woodboring Beetles(Coleoptera:Cerambycidae and Disteniidae):Primary Types of the Smithsonian Institution(edited by S.W.Lingafelter et al.,Smithsonian Institution Scholarly Press,Washington D.C.,USA.2014,390 pages)显示文摘This book was written by five authors.I had met two of them,the first and third author.The first author,Steven Wayne Lingafelter,is a research entomologist with the Systematic Entomology Laboratory,USDA,based at the Smithsonian Institution’s National Museum of Natural History.He has specialized on longhorned woodboring beetles for almost three decades and currently specializes on the Neotropical fauna.He was a former | Meiying Lin | 2016 | Zoological Systematics2016，41，2： | 0 |
| 8 | Biodegradable calcium sulfide-based nanomodulators for H_(2)S-boosted Ca^(2+)-involved synergistic cascade cancer therapy显示文摘Hydrogen sulfide(H_(2)S)is the most recently discovered gasotransmitter molecule that activates multiple intracellular signaling pathways and exerts concentration-dependent antitumor effect by interfering with mitochondrial respiration and inhibiting cellular ATP generation.Inspired by the fact that H_(2)S can also serve as a promoter for intracellular Ca^(2+)influx,tumor-specific nanomodulators(I-CaS@PP)have been constructed by encapsulating calcium sulfide(CaS)and indocyanine green(ICG)into methoxy poly(ethylene glycol)-b-poly(lactide-co-glycolide)(PLGA-PEG).I-CaS@PP can achieve tumor-specific biodegradability with high biocompatibility and pH-responsive H_(2)S release.The released H_(2)S can effectively suppress the catalase(CAT)activity and synergize with released Ca^(2+)to facilitate abnormal Ca^(2+)retention in cells,thus leading to mitochondria destruction and amplification of oxidative stress.Mitochondrial dysfunction further contributes to blocking ATP synthesis and downregulating heat shock proteins(HSPs)expression,which is beneficial to overcome the heat endurance of tumor cells and strengthen ICG-induced photothermal performance.Such a H_(2)S-boosted Ca^(2+)-involved tumor-specific therapy exhibits highly effective tumor inhibition effect with almost complete elimination within 14-day treatment,indicating the great prospect of CaS-based nanomodulators as antitumor therapeutics. | Chuchu Lin Chenyi Huang Zhaoqing Shi Meitong Ou Shengjie Sun Mian Yu Ting Chen Yunfei Yi Xiaoyuan Ji Feng Lv Meiying Wu Lin Mei | 2022 | Acta Pharmaceutica Sinica B2022，12，12： | 0 |
| 9 | A survey of the tribe Mesosini Mulsant (Coleoptera: Cerambycidae) from Beijing, China显示文摘Four species of the tribe Mesosini Mulsant,1839 are recorded from Beijing,the capital of the People's Republic of China:Agelasta(Mesolophus)marmorata(Pic,1927),Mesosa(Perimesosa)atrostigma Gressitt,1942,M.(P.)hyunchaei Yamasako&Hasegawa,2009,and M.(Mesosa)myops(Dalman,1817).M.(P.)hyunchaei Yamasako&Hasegawa,2009 is recorded from China for the first time,including Beijing and Jiangsu. | Jian Sun Siqin Ge Nengwen Xiao Meiying Lin | 2022 | Zoological Systematics2022，47，4： | 0 |
| 10 | FGF8 signaling sustains progenitor status and multipotency of cranial neural crest-derived mesenchymal cells in vivo and in vitro显示文摘The cranial neural crest(CNC)cells play a vital role in craniofacial development and regeneration.They are multi-potent progenitors,being able to differentiate into various types of tissues.Both pre-migratory and post-migratory CNC cells are plastic,taking on diverse fates by responding to different inductive signals.However,what sustains the multipotency ofCNCcells andderivatives remains largely unknown.In this study,we present evidence that FGF8 signaling is able to sustain progenitor status and multipotency of CNC-derived mesenchymal cells both in vivo and in vitro.We show that augmented FGF8 signaling in pre-migratory CNC cells prevents cell differentiation and organogenesis in the craniofacial region by maintaining their progenitor status.CNC-derived mesenchymal cells with Fgf8 overexpression or control cells in the presence of exogenous FGF8 exhibit prolonged survival,proliferation,and multi-potent differentiation capability in cell cultures.Remarkably,exogenous FGF8 also sustains the capability of CNC-derived mesenchymal cells to participate in organogenesis such as odontogenesis.Furthermore,FGF8-mediated signaling strongly promotes adipogenesis but inhibits osteogenesis of CNC-derived mesenchymal cells in vitro.Our results reveal a specific role for FGF8 in the maintenance of progenitor status and in fate determination of CNC cells,implicating a potential application in expansion and fate manipulation of CNC-derived cells in stem cell-based craniofacial regeneration. | Meiying Shao Chao Liu Yingnan Song Wenduo Ye Wei He Guohua Yuan Shuping Gu Congxin Lin Liang Ma Yanding Zhang Weidong Tian Tao Hu YiPing Chen | 2015 | Journal of Molecular Cell Biology2015，7，5： | 0 |
| 11 | Tumor Microenvironment-Specific Chemical Internalization for Enhanced Gene Therapy of Metastatic Breast Cancer显示文摘Benefiting from treating diseases at the genetic level,gene therapy has been considered a new revolution in the biomedical field.However,the extracellular and intracellular barriers during gene transport such as enzymatic degradation and endo-/lysosomal sequestration significantly compromise the therapeutic efficacy.Though photochemical internalization(PCI)has emerged as a promising approach for causing endo-/lysosomal leakage with translocation of the internalized molecules into the cytosol,its effect is still unsatisfactory due to the insufficient light penetration depth.Here,we develop tumor microenvironment-specific enhanced gene delivery by means of ROS generated from the in situ cascaded catalytic reactions in tumors involving GOx-mediated redox reaction and Mn2+-mediated Fenton-like reaction.The efficient enzymatic protection and successful endo-/lysosomal escape of cargo gene complexes have been demonstrated.Moreover,anti-Twist siRNA-loaded G@MMSNs-P exhibit tumor-specific biodegradation,excellent T1-weighted MR imaging,and significant inhibitory effects against breast cancer growth and pulmonary metastasis. | Yun Zhou Mian Yu Changjun Tie Yang Deng Junqing Wang Yunfei Yi Fan Zhang Chenyi Huang Hairong Zheng Lin Mei Meiying Wu | 2021 | Research2021，，1： | 0 |
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