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| 1 | Tissue clearing of both hard and soft tissue organs with the PEGASOS method显示文摘织物空地技术由转织物在 3 尺寸(3-D ) 启用不透明的机关和纸巾的可视化透明。当前的组织空地方法被能与每个单个协议被清除的纸巾的有限类型限制,它不可避免地导致了存在在整个身体或身体部分成像以内盲点。包括骨头和牙齿的难纸巾仍然是要清除的最困难的机关。另外,内长的荧光的损失为基于溶剂的空地方法仍然是一颗主要担心。这里,我们发展了聚乙烯乙二醇(木钉) 联系了溶剂系统(PEGASOS ) ,它将近显示了纸巾的所有类型透明、保存的内长的荧光。骨头和牙齿能被转在变清以后将近不可见。PEGASOS 方法转了透明的整个成年老鼠身体,我们对一个成年老鼠头骨头,牙齿,大脑,肌肉,和其它填写了的图象有能力没有盲目区域的纸巾。难织物透明性使我们能重建在 3-D 的未经触动的上颚,牙齿,腿节,或膝关节。另外,我们在长距离上在亚 cellular 分辨率并且到踪迹个人神经原和轴突管理了未经触动的鼠标大脑到图象。我们也通过 vertebrae 直接设想了背面的根中心。最后,我们在长骨头的髓空间以内在 3-D 揭示了神经网络的分发模式。这些结果建议 PEGASOS 方法是为一般生物医学的研究的一个有用工具。 | Dian Jing Shiwen Zhang Wenjing Luo Xiaofei Gao Yi Men Chi Ma Xiaohua Liu Yating Yi Abhijit Bugde Bo O. Zhou Zhihe Zhao Quan Yuan Jian Q. Feng Liang Gao Woo-Ping Ge Hu Zhao | 2018 | Cell Research2018，28，8： | 18 |
| 2 | Effect of polymorphism and type II diabetes on aspirin resistance in patients with unstable coronary artery disease显示文摘 | GAO Fei WANG Zan-xin MEN Jian-long REN Jing WEI Min-xin | 2011 | Chinese Medical Journal2011，，11： | 8 |
| 3 | Relationship with spatial memory in diabetic rats and protein kinase Cγ,caveolin-1 in the hippocampus and neuroprotective effect of catalpol显示文摘 | Zhou Haicheng Liu Jing Ren Liyuan Liu Wei Xing Qian Men Lili Song Guirong Du Jianling | 2014 | Chinese Medical Journal2014，，5： | 7 |
| 4 | The FAST Galactic Plane Pulsar Snapshot survey:I.Project design and pulsar discoveries显示文摘Discovery of pulsars is one of the main goals for large radio telescopes.The Five-hundredmeter Aperture Spherical radio Telescope(FAST),that incorporates an L-band 19-beam receiver with a system temperature of about 20 K,is the most sensitive radio telescope utilized for discovering pulsars.We designed the snapshot observation mode for a FAST key science project,the Galactic Plane Pulsar Snapshot(GPPS)survey,in which every four nearby pointings can observe a cover of a sky patch of 0.1575 square degrees through beam-switching of the L-band 19-beam receiver.The integration time for each pointing is 300 seconds so that the GPPS observations for a cover can be made in 21 minutes.The goal of the GPPS survey is to discover pulsars within the Galactic latitude of±10∘from the Galactic plane,and the highest priority is given to the inner Galaxy within±5∘.Up to now,the GPPS survey has discovered 201 pulsars,including currently the faintest pulsars which cannot be detected by other telescopes,pulsars with extremely high dispersion measures(DMs)which challenge the currently widely used models for the Galactic electron density distribution,pulsars coincident with supernova remnants,40 millisecond pulsars,16 binary pulsars,some nulling and mode-changing pulsars and rotating radio transients(RRATs).The follow-up observations for confirmation of new pulsars have polarization-signals recorded for polarization profiles of the pulsars.Re-detection of previously known pulsars in the survey data also leads to significant improvements in parameters for 64 pulsars.The GPPS survey discoveries are published and will be updated at http://zmtt.bao.ac.cn/GPPS/. | J.L.Han Chen Wang P.F.Wang Tao Wang D.J.Zhou Jing-Hai Sun Yi Yan Wei-Qi Su Wei-Cong Jing Xue Chen X.Y.Gao Li-Gang Hou Jun Xu K.J.Lee Na Wang Peng Jiang Ren-Xin Xu Jun Yan Heng-Qian Gan Xin Guan Wen-Jun Huang Jin-Chen Jiang Hui Li Yun-Peng Men Chun Sun Bo-Jun Wang H.G.Wang Shuang-Qiang Wang Jin-Tao Xie Heng Xu Rui Yao Xiao-Peng You D.J.Yu Jian-Ping Yuan Rai Yuen Chun-Feng Zhang Yan Zhu | 2021 | Research in Astronomy and Astrophysics2021，21，5： | 4 |
| 5 | Oxidized mitochondrial DNA sensing by STING signaling promotes the antitumor effect of an irradiated immunogenic cancer cell vaccine显示文摘Exposure to ionizing radiation,a physical treatment that inactivates live tumor cells,has been extensively applied to enhance the antitumor responses induced by cancer cell vaccines in both animal research and human clinical trials.However,the mechanisms by which irradiated cells function as immunogenic tumor vaccines and induce effective antitumor responses have not been fully explored.Here,we demonstrate that oxidized mitochondrial DNA(mtDNA)and stimulator of interferon genes(STING)signaling play a key roles in the enhanced antitumor effect achieved with an irradiated tumor cell vaccine.Elevations in ROS and oxidized mtDNA 8-OHG content could be induced in irradiated tumor cells.Oxidized mtDNA derived from irradiated tumor cells gained access to the cytosol of dendritic cells(DCs).Oxidized mtDNA,as a DAMP or adjuvant,activated the STING-TBK1-IRF3-IFN-β pathway in DCs,which subsequently cross-presented irradiated tumor cell-derived antigens to CD8^(+)T cells and elicited antitumor immunity.The results of our study provide insight into the mechanism by which an irradiated cell vaccine mediates antitumor immunity,which may have implications for new strategies to improve the efficacy of irradiated vaccines. | Chunju Fang Fei Mo Li Liu Jing Du Min Luo Ke Men Feifei Na Wei Wang Hanshuo Yang Xiawei Wei | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 6 | Chinese perceptions of the European Union: A review of leading Chinese journals显示文摘 | MEN Jing | 2006 | European Law Journal2006，12，6： | 1 |
| 7 | Loss of liver kinase B1 causes planar polarity defects in cochlear hair cells in mice显示文摘 | Yuqin Men Aizhen Zhang Liwen Zhang Yecheng Jin Zhishuo Wang Jing Zhao Xiaolin Yu Jian Zhang Jiangang Gao | 2016 | Frontiers of Medicine2016，10，4： | 1 |
| 8 | Sustainability of SARS-CoV-2 Induced Humoral Immune Responses in COVID-19 Patients from Hospitalization to Convalescence Over Six Months显示文摘Understanding the persistence of antibody in convalescent COVID-19 patients may help to answer the current major concerns such as the risk of reinfection,the protection period of vaccination and the possibility of building an active herd immunity.This retrospective cohort study included 172 COVID-19 patients who were hospitalized in Wuhan.A total of404 serum samples were obtained over six months from hospitalization to convalescence.Antibodies in the specimens were quantitatively analyzed by the capture chemiluminescence immunoassays(CLIA).All patients were positive for the anti-SARS-Co V-2 Ig M/Ig G at the onset of COVID-19 symptoms,and the Ig G antibody persisted in all the patients during the convalescence.However,only approximately 25%of patients can detect the Ig M antibodies,Ig M against N protein(NIg M)and receptor binding domain of S protein(RBD-Ig M)at the 27 th week.The titers of Ig M,N-Ig M and RBD-Ig M reduced to 16.7%,17.6%and 15.2%of their peak values respectively.In contrast,the titers of Ig G,N-Ig G and RBD-Ig G peaked at 4–5 th week and reduced to 85.9%,62.6%and 87.2%of their peak values respectively at the end of observation.Dynamic behavior of antibodies and their correlation in age,gender and severity groups were investigated.In general,the COVID-19 antibody was sustained at high levels for over six months in most of the convalescent patients.Only a few patients with antibody reducing to an undetectable level which needs further attention.The humoral immune response against SARS-Co V-2 infection in COVID-19 patients exhibits a typical dynamic of acquired immunity. | Yang Zheng Qing Zhang Ashaq Ali Ke Li Nan Shao Xiaoli Zhou Zhiqin Ye Xiaomin Chen Shanshan Cao Jing Cui Juan Zhou Dianbing Wang Baidong Hou Min Li Mengmeng Cui Lihua Deng Xinyi Sun Qian Zhang Qinfang Yang Yong li Hui Wang Yake Lei Bo Yu Yegang Cheng Xiaolin Tong Dong Men Xian-En Zhang | 2021 | Virologica Sinica2021，36，5： | 1 |
| 9 | The Construction of the China-ASEAN Free Trade Area:A Study of China's Active Involvement显示文摘 | JING MEN | 2007 | Global Society2007，21，2： | 1 |
| 10 | A Study of Siliceous Pneumoconiosis in a Desert Area of Sunan County,Gansu Province,China显示文摘Three hundred and ninety five residents in a desert area were examined with chest radiographs and 28 cases with siliceous pneumoconiosis were found.The prevalence of siliceous pneumoconiosis was 7.09%,and that over 40 years of age was 21%.The histological findings of lungs from a camel living in that area for 20 years also confirmed to have siliceous pneumoconiosis. | XU XIU-ZHEN’, CAT XI-GUANG, MEN XIAN-SEN, YANG PENG-YUN, YANG JING-FU, JING SONG-LIN HE JI-HUA, AND SI WEI-YIPeople’s Hospital of Gansu Province Sunan County Hospital of Gansu Province, Lanzhou730000, China | 1993 | Biomedical and Environmental Sciences1993，6，3： | 1 |
| 11 | Catalyst-free growth of SiC nanowires in a porous graphite substrate by low pressure chemical vapor infiltration 显示文摘 | Yongsheng Liu Jing Men Wei Feng | 2014 | Ceramics International2014，40，11： | 1 |
| 12 | LEWIS ACIDIC SITES NOT ASSOCIATED WITH EXTRA-FRAMEWORK ALUMINUM IN DEHYDROXYLATED ZEOLITE HZSM-5显示文摘LEWISACIDICSITESNOTASSOCIATEDWITHEXTRA-FRAMEWORKALUMINUMINDEHYDROXYLATEDZEOLITEHZSM-5￥TieHongCHEN;PingChuanSUN;AiJuMEN;ZhongY... | Tie Hong CHEN Ping Chuan SUN Ai Ju MEN Zhong Yong Zhen Ya GUO Jing Zhong WANG Da Tong DING He Xuan LI (Department of Chemistry Nankai University Tianjin, 300071)(the State Key Laboratory of Funcrional Polymericmeric Materials for Adsorption and Sepa | 1996 | Chinese Chemical Letters1996，7，5： | 0 |
| 13 | Mapping of individual sensory nerve axons from digits to spinal cord with the transparent embedding solvent system显示文摘Achieving uniform optical resolution for a large tissue sample is a major challenge for deep imaging.For conventional tissue clearing methods,loss of resolution and quality in deep regions is inevitable due to limited transparency.Here we describe the Transparent Embedding Solvent System(TESOS)method,which combines tissue clearing,transparent embedding,sectioning and block-face imaging.We used TESOS to acquire volumetric images of uniform resolution for an adult mouse whole-body sample.The TESOS method is highly versatile and can be combined with different microscopy systems to achieve uniformly high resolution.With a light sheet microscope,we imaged the whole body of an adult mouse,including skin,at a uniform 0.8×0.8×3.5μm^(3) voxel resolution within 120 h.With a confocal microscope and a 40×/1.3 numerical aperture objective,we achieved a uniform sub-micron resolution in the whole sample to reveal a complete projection of individual nerve axons within the central or peripheral nervous system.Furthermore,TESOS allowed the first mesoscale connectome mapping of individual sensory neuron axons spanning 5 cm from adult mouse digits to the spinal cord at a uniform sub-micron resolution. | Yating Yi Youqi Li Shiwen Zhang Yi Men Yuhong Wang Dian Jing Jiayi Ding Qingjie Zhu Zexi Chen Xingjun Chen Jun-Liszt Li Yilong Wang Jun Wang Hanchuan Peng Li Zhang Wenjing Luo Jian Q.Feng Yongwen He Woo-Ping Ge Hu Zhao | 2024 | Cell Research2024，34，2： | 0 |
| 14 | A Heavy Metal Analysis Device Based on Light-addressable Potentiometric Sensor显示文摘<正>A full automatic device to detect heavy metal Hg,Fe,Cr elements based on thin-film sensitive materials prepared on surface of light-addressable potentiometric sensors (LAPS) by means of pulsed laser deposition PLD) technique is developed. High-purity chemical compound AgI:Ag_2S:HgI synthesized were used as target of PLD,thin film sensitive to Hg~ (2+) ion was prepared on the surface of LAPS.All-solide-state chalcogenide glass ion-selective electrodes ISE) ,Fe-ISE and Cr-ISE,were also used as targets of PLD,and thin-film sensors on different LAPS sensitive to Fe~ (3+) and Cr~ (6+) ions were prepared.The heavy metal analysis device with characteristics of collect sample in-site,real-time determination,communication and multifunction software were designed.Hardware design of the device mainly includes control and measurement aspects.The detected limits of Hg,Fe,Cr ions are 3.44×10~ (-7) mol/L,6.31×10~ (-6) mol/L and 2.09×10~ (-7) mol/L,respectively. | Hong Men Jianguo Wang Jing Gao Ping Wang | 2006 | 稀有金属材料与工程2006，35，A03： | 0 |
| 15 | Research on error accumulation control of three-dimensional adjustment with offset constraint显示文摘Background Currently,laser tracker is the primary instrument used to carry out three-dimensional position measurement in accelerator alignment.Theoretically,three-dimensional measuring data processed by three-dimensional adjustment are more rigorous,however,error accumulation is found in practice.Purpose In order to control error accumulation and further improve the measurement accuracy of accelerator alignment,this research introduces the laser alignment system into the activity of measurement and data processing.Methods A measurement scheme combining laser tracker and laser alignment system is proposed.To construct the constraint condition,the offset values from the measuring points to the laser straight-line datum were used.To carry out the three-dimensional adjustment with offset constraint,the laser tracker observations were used.Results A three-dimensional adjustment function model of laser tracker observations is given.The construction method of the constraint equation is researched,and the calculation formulas of the three-dimensional adjustment with offset constraint are derived.A 200 m linac tunnel control network is designed,using simulation measurement method,the measuring data of laser tracker and the offset values from the measuring points to the laser straight-line datum were generated.The simulated data are calculated by the method given in this paper and the result is analyzed.Conclusion Simulation result shows introducing the laser alignment system into laser tracker measurement and applying the three-dimensional adjustment with offset constraint can effectively suppress the error accumulation caused by long distance move station measurement. | Wang Xiaolong Kang Ling Dong Lan Li Bo Men Lingling Luo Tao Wang Tong Liang Jing He Zhenqiang Ke Zhiyong Ma Na Lu Shang Han Yuanying Yan Luping Zhang Luyan Liu Xiaoyang Yan Haoyue Li Chunhua Wu Lei | 2022 | Radiation Detection Technology and Methods2022，6，4： | 0 |
| 16 | 3' Noncoding Region Construction of GHR Gene-luciferase Report Vector and Valuation显示文摘To analyze miR-139 target sites in 3' UTR of GHR gene in dairy cow mammary gland, a GHR 3' UTR- luciferase reporter vector was constructed and the effect of miRNA on its activity was evaluated in dairy cow mammary gland epithelial cells (DCMECs). The miR-139 targeting GHR 3' UTR was predicted by Target Scan 5.1 software, 3' UTR fragment of GHR was amplified by PCR from RNA of DCMECs. PCR products were cloned into SpeⅠ/Hind Ⅲ modified pMIR-Report vector. The luciferase reporter vector and miRNA eukaryotic expression vector were transferred into DCMECs using lipofectamine 2000 transfection reagent. The dual-luciferase reporter assay system was used to quantitiate the reporter activity. The results showed that a 107 bp 3' UTR fragment of GHR gene was successfully cloned into the pMIR-Report vector, which authenticated by SpeⅠ/Hind Ⅲ digestion and DNA sequencing. The luciferase activity of reporter construction treated with miR-139 decreased 20.87% compared with the control group. It was concluded that the GHR3' UTR-luciferase reporter vector had been successfully constructed. The luciferase activity of the reporter could be suppressed by miR-139. | Jie Jing Men Jing Wang Chun-mei Gao Xue-jun Li Qing-zhang | 2012 | Journal of Northeast Agricultural University(English Edition)2012，19，2： | 0 |
| 17 | Facile fabrication of covalent organic framework functionalized superhydrophobic porous sponges for highly efficient water/oil separation显示文摘Considering the serious environmental pollution and economic losses caused by increasing oil spills and chemical leaks,effective and eco-friendly methods of oil/water separation should be urgently developed.Herein,a facile strategy(about 20 min)was developed for integrating covalent organic framework(COF)particles with melamine sponges(MS)by covalent bonding,and then a superhydrophobic COF/MS composite(denoted OA-CP@MS)could be further obtained by following modification with a 1-octadecylamine/water dispersion.Specifically,the synthesis process was developed under a mild condition that avoids the need for sealing and high-temperature treatments.It was proven that the fabricated OA-CP@MS presented a prominent absorption capacity for various organic reagents,in which adsorption capacity of chloroform could be up to 173 g/g.Owing to its excellent chemical robustness in strong alkaline and saline environments and in various organic solvents,the prepared OACP@MS showed a great potential to perform oil/water separation in complex practical conditions.Its rapid preparation process,fluorine-free treatment,and water-based modification would extend the application of COF materials in oil/water separation. | WANG Jing WANG FuShan ZHOU YuJian ZHOU YongJun GAO Peng MEN XueHu | 2022 | Science China(Technological Sciences)2022，65，11： | 0 |
| 18 | Promoting effect of periodic case analysis test on pathophysiology teaching显示文摘AIM:To explore the effect of the periodic case analysis test on pathophysiology teaching.METHODS:We randomly selected two natural classes from Grade 2011 Clinical Medicine Specialty in our university and set them as experimental group and control group.There were 66 and 68 students in the two groups,respectively.For these two groups,the course background,pathophysiology course teaching and final exam conditions were all the same.In the teaching process,we had a written test every 8 teaching hours,5 times in each group.In experimental group,students were arranged to face some typical clinical cases,they must analyze and discuss the specific pathogenesis according to the recent theoretical knowledge.In the same teaching time,the control students need to complete a certain amount of traditional type homework which was mainly basic concepts,basic pathogenesis and no practical case analysis.We compared and analyzed the final test scores and the pass rates in the two groups,and calculated the mean rank sums of the examination results with nonparametric method Kruskal-Wallis test.RESULTS:The average score of the final exam was 82.69 in experimental group,but that in control group was 77.98.The pass rates were 89.5%and 81.2%in the two groups,respectively.The average test rank scores were 171.84 and 136.95,respectively.CONCLUSION:The periodic case analysis test can obviously improve the students'academic achievements,and has promoting effect on pathophysiology teaching. | ZHAO Li-jun MEN Xiu-li WU Jing KONG Xiao-yan LI Hong-jie LIU Li-hua | 2013 | 中国病理生理杂志2013，29，10： | 0 |
| 19 | Emmanuel Macron réélu:une diplomatieéquilibiée显示文摘 | MEN JING | 2022 | 今日中国(法文版)2022，60，5： | 0 |
| 20 | The concordance between the evolutionary trend and the clinical manifestation of the two SARS-CoV-2 variants显示文摘Coronavirus disease 2019(COVID-19),the disease caused by infection with severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),has developed into a global pandemic that continues to pose an enormous threat to public health and the global economy.Since the first SARS-CoV-2 genome was released[1],thousands of genetic variants have been identified in SARS-CoV-2 strains isolated from worldwide patients. | Ben Hu Ran Liu Xiaolu Tang Yuchen Pan Ming Wang Yongqing Tong Guangming Ye Gaigai Shen Ruochen Ying Aisi Fu Di Li Wanxu Zhao Jing Peng Jie Guo Dong Men Xinmin Yao Yirong Wang Hong Zhang Zhihui Feng Junping Yu Liangjun Chen Zixin Deng Xuemei Lu Ya-Ping Zhang Yirong Li Bende Liu Lilei Yu Yan Li Jian Lu Tiangang Liu | 2021 | National Science Review2021，8，8： | 0 |
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