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| 1 | Discrimination of False Negative Results in RT-PCR Detection of SARS-CoV-2 RNAs in Clinical Specimens by Using an Internal Reference显示文摘Reverse transcription-polymerase chain reaction(RT-PCR)is an essential method for specific diagnosis of SARS-CoV-2 infection.Unfortunately,false negative test results are often reported.In this study,we attempted to determine the principal causes leading to false negative results of RT-PCR detection of SARS-CoV-2 RNAs in respiratory tract specimens.Multiple sputum and throat swab specimens from 161 confirmed COVID-19 patients were tested with a commercialfluorescent RT-PCR kit targeting the ORF1 ab and N regions of SARS-CoV-2 genome.The RNA level of a cellular housekeeping gene ribonuclease P/MRP subunit p30(RPP30)in these specimens was also assessed by RT-PCR.Data for a total of 1052 samples were retrospectively re-analyzed and a strong association between positive results in SARS-CoV-2 RNA tests and high level of RPP30 RNA in respiratory tract specimens was revealed.By using the ROC-AUC analysis,we identified Ct cutoff values for RPP30 RT-PCR which predicted false negative results for SARS-CoV-2 RT-PCR with high sensitivity(95.03%–95.26%)and specificity(83.72%–98.55%)for respective combination of specimen type and ampli-fication reaction.Using these Ct cutoff values,false negative results could be reliably identified.Therefore,the presence of cellular materials,likely infected host cells,are essential for correct SARS-CoV-2 RNA detection by RT-PCR in patient specimens.RPP30 could serve as an indicator for cellular content,or a surrogate indicator for specimen quality.In addition,our results demonstrated that false negativity accounted for a vast majority of contradicting results in SARS-CoV-2 RNA test by RT-PCR. | Yafei Zhang Changtai Wang Mingfeng Han Jun Ye Yong Gao Zhongping Liu Tengfei He Tuantuan Li Mengyuan Xu Luping Zhou Guizhou Zou Mengji Lu Zhenhua Zhang | 2020 | Virologica Sinica2020，35，6： | 5 |
| 2 | Configuration of nucleolar DNA in situ in nucleolus of Allium cepa cells显示文摘The location and configuration of nucleolar DNA have not been determined for a long time. In this paper, we have observed the nucleolar infrastructure and the character of nucleolar DNA in Allium cepa cells by conventional electron microscopy and the cytochemical NAMA-Ur DNA specific staining method. Furthermore, we have properly improved the NAMA-Ur method so as to analyze the location and configuration of nucleolar DNA in situ. Our results indicated that the nucleolar DNA in Allium cepa cells is mainly located at the border between fibrillar centers and dense fibribllar component, especially distributed in the configuration of encircling the fibrillar centers. | TAO Wei HE Jie JIAO Mingda HE Mengyuan HAO Shui | 2001 | Chinese Science Bulletin2001，46，1： | 1 |
| 3 | Interfacial induction and regulation for microscale crystallization process:a critical review显示文摘Microscale crystallization is at the frontier of chemical engineering,material science,and biochemical research and is affected by many factors.The precise regulation and control of microscale crystal processes is still a major challenge.In the heterogeneous induced nucleation process,the chemical and micro/nanostructural characteristics of the interface play a dominant role.Ideal crystal products can be obtained by modifying the interface characteristics,which has been proven to be a promising strategy.This review illustrates the application of interface properties,including chemical characteristics(hydropho-bicity and functional groups)and the morphology of micro/nanostructures(rough structure and cavities,pore shape and pore size,surface porosity,channels),in various microscale crystallization controls and process intensification.Finally,possible future research and development directions are outlined to emphasize the importance of interfacial crystallization control and regulation for crystal engineering. | Mengyuan Wu Zhijie Yuan Yuchao Niu Yingshuang Meng Gaohong He Xiaobin Jiang | 2022 | Frontiers of Chemical Science and Engineering2022，16，6： | 1 |
| 4 | Geological characteristics and metallogenic prospect of marine volcanic rock-type copper deposits in eastern Kunlun Mountains area, Xinjiang显示文摘The Katelixi Cu-Zn deposit is a marine volcanic rock-type copper deposit discovered for the first time in the Tokuzidaban Group in eastern Kunlun Mountains area. It is hosted in the Lower Carboniferous Tokuzidaban Group volcanic strata. The orebodies are obviously controlled by the strata and their ore-bearing rocks are a suite of greyish-green mafic tuffs, generally parallel-stratiform, stratoid and lenticular in form, occurring in limestone as well as in the contact between limestone and carbon-bearing siltstone. This ore deposit possesses distinct characteristics of marine volcanic rock sedimentaion. The geological, petrochemical and REE characteristics of its occurrence pro-vide strong evidence suggesting that this deposit is of marine volcanic rock sedimention origin, basically identical to those of some typical marine volcanic rock-type copper deposits in Xinjiang and other parts of China. Marine vol-canic rocks are well developed in the Lower Carboniferous Tokuzidaban strata in eastern Kunlun Mountains area. In addition to this deposit, we have also found a number of copper polymetallic ore deposits or occurrences in associa-tion with marine volcanc activities in many places where there is a good metallogenic prospect. A breakthrough in the understanding of ore prospecting and genesis has not only filled up the gap in prospecting this type of ore depos-its in this area, but also is of great significance in directing exploration of this type of ore deposits in this area. | HAN Hongwei WANG He MU Lunxun WEI Yong ZHI Jianhong YU Jianhua WEI Mengyuan | 2011 | Chinese Journal Of Geochemistry2011，30，4： | 1 |
| 5 | Co‑packaged optics(CPO):status,challenges,and solutions显示文摘Due to the rise of 5G,IoT,AI,and high-performance computing applications,datacenter trafc has grown at a compound annual growth rate of nearly 30%.Furthermore,nearly three-fourths of the datacenter trafc resides within datacenters.The conventional pluggable optics increases at a much slower rate than that of datacenter trafc.The gap between application requirements and the capability of conventional pluggable optics keeps increasing,a trend that is unsustainable.Copackaged optics(CPO)is a disruptive approach to increasing the interconnecting bandwidth density and energy efciency by dramatically shortening the electrical link length through advanced packaging and co-optimization of electronics and photonics.CPO is widely regarded as a promising solution for future datacenter interconnections,and silicon platform is the most promising platform for large-scale integration.Leading international companies(e.g.,Intel,Broadcom and IBM)have heavily investigated in CPO technology,an inter-disciplinary research feld that involves photonic devices,integrated circuits design,packaging,photonic device modeling,electronic-photonic co-simulation,applications,and standardization.This review aims to provide the readers a comprehensive overview of the state-of-the-art progress of CPO in silicon platform,identify the key challenges,and point out the potential solutions,hoping to encourage collaboration between diferent research felds to accelerate the development of CPO technology. | Min Tan Jiang Xu Siyang Liu Junbo Feng Hua Zhang Chaonan Yao Shixi Chen Hangyu Guo Gengshi Han Zhanhao Wen Bao Chen Yu He Xuqiang Zheng Da Ming Yaowen Tu Qiang Fu Nan Qi Dan Li Li Geng Song Wen Fenghe Yang Huimin He Fengman Liu Haiyun Xue Yuhang Wang Ciyuan Qiu Guangcan Mi Yanbo Li Tianhai Chang Mingche Lai Luo Zhang Qinfen Hao Mengyuan Qin | 2023 | Frontiers of Optoelectronics2023，16，1： | 1 |
| 6 | Autocatalytic reduction-assisted synthesis of segmented porous PtTe nanochains for enhancing methanol oxidation reaction显示文摘Morphology engineering has been developed as one of the most widely used strategies for improving the performance of electrocatalysts.However,the harsh reaction conditions and cumbersome reaction steps during the nanomaterials synthesis still limit their industrial applications.Herein,one-dimensional(1D)novel-segmented PtTe porous nanochains(PNCs)were successfully synthesized by the template methods assisted by Pt autocatalytic reduction.The PtTe PNCs consist of consecutive mesoporous architectures that provide a large electrochemical surface area(ECSA)and abundant active sites to enhance methanol oxidation reaction(MOR).Furthermore,1D nanostructure as a robust sustaining frame can maintain a high mass/charge transfer rate in a long-term durability test.After 2,000 cyclic voltammetry(CV)cycles,the ECSA value of PtTe PNCs remained as high as 44.47 m^(2)·gPt^(-1),which was much larger than that of commercial Pt/C(3.95 m^(2)·gPt^(-1)).The high catalytic activity and durability of PtTe PNCs are also supported by CO stripping test and density functional theory calculation.This autocatalytic reduction-assisted synthesis provides new insights for designing efficient low-dimensional nanocatalysts. | Qiqi Zhang Tianyu Xia He Huang Jialong Liu Mengyuan Zhu Hao Yu Weifeng Xu Yuping Huo Congli He Shipeng Shen Cong Lu Rongming Wang Shouguo Wang | 2023 | Nano Research Energy2023，2，1： | 1 |
| 7 | Kidney organoids as a promising tool in nephrology显示文摘Kidney disease has become a global public health problem affecting over 750 million people worldwide and imposing a heavy economic burden on patients.The complex architecture of the human kidney makes it very difficult to study the pathophysiology of renal diseases in vitro and to develop effective therapeutic options for patients.Even though cell lines and animal models have enriched our understanding,they fail to recapitulate key aspects of human kidney development and renal disease at cellular and functional levels.Organoids can be derived from either pluripotent stem cells or adult stem cells by strictly regulating key signalling pathways.Today,these self-differentiated organoids represent a promising technology to further understand the human kidney,one of the most complex organs,in an unprecedented way.The newly established protocols improved by organ-on-chip and coculture with immune cells will push kidney organoids towards the next generation.Herein,we focus on recent achievements in the application of kidney organoids in disease modelling,nephrotoxic testing,precision medicine,biobanking,and regenerative therapy,followed by discussions of novel strategies to improve their utility for biomedical research.The applications we discuss may help to provide new ideas in clinical fields. | Mengyuan Wu Tingting Hu Ping Zhu Moussa Ide Nasser Jie Shen Fang Sun Qingnan He Mingyi Zhao | 2022 | Genes & Diseases2022，9，3： | 1 |
| 8 | A novel modified paclitaxel-loaded discoidal recombinant high-density lipoproteins:Preparation,characterizations and in vivo evaluation显示文摘This study is one of the first to focus on the unexpected drug leakage from discoidal recombinant high-density lipoproteins(d-rHDLs)as a consequence of remodeling process,mainly associated with lecithin-cholesterol acyltransferase(LCAT)during their metabolic process.Here,a newly monocholesterylsuccinate(CHS)modified paclitaxel-loaded drHDLs(cP-d-rHDLs)were constructed successfully through structural modification,thus aiming to improve the performance of d-rHDLs.And next their in vitro physiochemical properties and pharmacokinetics in SpragueeDawley rats were elaborately investigated.Collectively our studies demonstrated that cP-d-rHDLs,whose remodeling behaviors were restrained effectively after structural modification,exhibited more excellent and promising properties as novel delivery vehicles for anti-cancer agents. | Mengyuan Zhang Junting Jia Jianping Liu Hongliang He Lisha Liu | 2013 | Asian Journal of Pharmaceutical Sciences2013，8，1： | 1 |
| 9 | Enhanced multiple anchoring and catalytic conversion of polysulfides by SnO_(2)-decorated MoS_(2) hollow microspheres for high-performance lithium-sulfur batteries显示文摘Lithium-Sulfur(Li-S)batteries are very competitive in energy storage equipment due to their high theoretical capacity and low cost of raw materials.However,the serious polysulfide'shuttle effect',volume expansion effect and slow conversion reaction kinetics of Li-S batteries during the charge/discharge cycle process still need to be resolved urgently.Herein,we prepared a novel sulfur host of SnO_(2)-decorated MoS_(2) hollow microspheres(SnO_(2)-MoS_(2) HMSs).The unique hollow structure provides enough space to accommodate a large amount of sulfur and effectively adapts to its large volume expansion during charge and discharge process.On the other hand,the SnO_(2) nanoparticles that attached to the surface of the MoS_(2) nanosheets will accelerate the catalysis of MoS_(2) and enhance the bonding strength with the polysulfide intermediates through the S-Sn-O chemical bond,which further inhibits the shuttle effect.The newly synthesized SnO_(2)-MoS_(2) HMSs cathode has achieved excellent electrochemical performance.The initial discharge specific capacity of 1326.4 mAh g^(-1) was obtained at 0.2 C,and after 100 cycles,the specific capacity of the SnO_(2)-MoS_(2) HMSs/S cathode only decreased slightly to 1183.8 mAh g^(-1),its capacity retention rate reaching as high as 89.2%.We expect the newly synthesized hollow structured MoS_(2) with SnO_(2) decoration provides a new strategy for the construction of Li-S battery cathode materials. | Yun Tian Zhengyu Wei Fan Li Songjie Li Lixiang Shao Mengyuan He Panfei Sun Yuanyuan Li | 2022 | Journal of Materials Science & Technology2022，，5： | 0 |
| 10 | Magnetoresistance anomaly in Fe_(5)GeTe_(2)homo-junctions induced by its intrinsic transition显示文摘Two-dimensional van der Waals(2D vdW)magnets have attracted great attention recently and possess the unprecedented advantages of incorporating high-quality vdW heterostructures and homostructures into spintronic devices,and exploring various physical phenomena or technologies.Among them,Fe_(5)GeTe_(2)(F5GT)has ferromagnetic order close to room temperature,however the magnetic properties near its intrinsic transitions and F5GT-based 2D devices remain mostly unexplored.Here,we systematically demonstrate the peculiar magnetic properties of Fe_(5)GeTe_(2)nanoflakes near its intrinsic transition temperature(Tp)which is far lower than its Curie temperature(TC)of~265 K,and firstly discover anomalous magnetoresistance effect in F5GT homo-junctions by magneto-transport measurements.The strongest anomalous Hall effect occurs around Tp which is located in a temperature range from 130 to 160 K for the F5GT nanoflakes with different thicknesses.Furthermore,negative magnetoresistance(N-MR)and butterfly-shaped magnetoresistance(B-MR)are observed in F5GT homo-junction devices,and they appeared only in an intermediate temperature range from 110 to 160 K,noticeably showing the maxima near the T_(p)rather than the lowest temperature.Our experimental results clearly reveal the significant influence of intrinsic transitions on magnetic properties of F5GT and magnetoresistance effect in F5GT homo-junction devices,which imply a new strategy to achieve highperformance 2D spintronic devices by tuning intrinsic magnetic or structural transitions in 2D vdW magnets. | Ruijie Zhao Yanfei Wu Shaohua Yan Xinjie Liu He Huang Yang Gao Mengyuan Zhu Jianxin Shen Shipeng Shen Weifeng Xu Zeyu Zhang Liyuan Zhang Jingyan Zhang Xinqi Zheng Hechang Lei Ying Zhang Shouguo Wang | 2023 | Nano Research2023，16，7： | 0 |
| 11 | A generic approach yields organic solar cells with enhanced efficiency and thermal stability显示文摘The use of deuterium are critical for promoting the fundamental understanding of aggregate materials and their new functions.Particularly,the solution structure of conjugated polymers can be hardly resolved without deuteration.However,studies about the isotopic effects of casting solvents on the aggregated structures of photovoltaic polymers and their bulk-heterojunction blends are deficient.Here,the impact of deuterated solvents on the thermal behavior,aggregated structures,and device performance of photovoltaic polymers is clearly delineated for the first time by multiple techniques.The enhanced π-π stacking order of photovoltaic polymers is highly relevant to their relatively poor miscibility with deuterated solvents.Benefiting from higher crystallinity and optimized morphology of deuterated solvents processed films,the devices are able to achieve better efficiency and notable improvement in thermal stability.Our results highlight the isotopic effects of solvents on the aggregated structure of conjugated polymer systems and reveal the potential of innovative approaches to fabricate thermally stable high-efficiency solar cells. | Mengyuan Gao Kai Zhang Chunyong He Hanqiu Jiang Xiong Li Qingchun Qi Kangkang Zhou Yu Chen Wenchao Zhao Long Ye | 2023 | Aggregate2023，4，2： | 0 |
| 12 | 8.30%Efficiency P3HT-based all-polymer solar cells enabled by a miscible polymer acceptor with high energy levels and efficient electron transport显示文摘P3HT stands out from numerous polymer donors owing to the merits of low cost and high scalability of synthesis.However,the photovoltaic performance of P3HT-based blends lags significantly behind the state-of-the-art systems,especially for all-polymer solar cells(APSCs) that generally show efficiency of around 3%–4% due to the lack of matched polymer acceptors.Herein,a polymer acceptor,named IDTBTC8-CN,was designed and synthesized with indacenodithiophene(IDT) and mono-cyano(CN)-substituted benzothiadiazole(BT-CN) as building blocks.Introducing a CN group endowed the polymer with decreased bandgap,and apparent n-type charge transport character despite the relatively high energy levels.Additionally,IDTBTC8-CN showed largely improved miscibility with P3HT,compared with that of BT-based control polymer IDTBTC8.The high miscibility between P3HT and IDTBTC8-CN as well as the amorphous aggregation behavior of IDTBTC8-CN enabled a broad manipulation room for the blend film to acquire favorable morphology.Eventually,a champion efficiency of 8.30% was achieved,in sharp contrast to that of the IDTBTC8-based system(1.21%).Such efficiency is a new record for P3HT-based APSCs reported so far.Moreover,P3HT:IDTBTC8-CN blend film also exhibited excellent mechanical robustness.This study implies the guidance of molecular design of the polymer acceptors and morphology control for P3HT-based APSCs. | Ziqi Liang Jiangting He Bin Zhao Mengyuan Gao Yu Chen Long Ye Miaomiao Li Yanhou Geng | 2023 | Science China Chemistry2023，66，1： | 0 |
| 13 | Abnormal chemical composition fluctuations in multi-principal-element alloys induced by simple cyclic deformation显示文摘High entropy alloys exhibit excellent combination of mechanical properties because of the unique com-position fluctuations,termed as‘concentration wave’.The concentration wave was closely related to mul-tiple aspects,including the fluctuation of local strain energy,local atomic environment,electronegativity,etc.Here we report for the first time that the amplitude of the concentration wave can be mechani-cally tailored under cyclic deformation in a well-known Cantor alloy.Atomic-scale energy-dispersive X-ray spectroscopy(EDS)mapping reveals that cyclic deformation may dynamically induce the clustering of solute atoms with a size of 1-3 nm,thus resulting in a higher concentration wave amplitude.The con-centration wave promotes strong interactions between dislocations and local solute clusters.Aside from the typical Taylor strengthening contribution due to the presence of isolated dislocations,the strength enhancement from the mechanically induced composition fluctuations was quantified to be as high as∼70 MPa,about one-third of the yield strength of the alloy without pre-deformation.This opens up a novel strategy of designing high strength alloys by tailoring solute configurations. | Mengyuan He Nan Jia Xiaochun Liu Yongfeng Shen Liang Zuo | 2022 | Journal of Materials Science & Technology2022，，18： | 0 |
| 14 | Manipulating internal flow units toward favorable plasticity in Zr-based bulk-metallic glasses by hydrogenation显示文摘This work intends to manipulate the internal flow units in Zr_(55)Cu_(30)Ni_(5)Al_(10)bulk-metallic glasses(BMGs)through plasma-assisted hydrogenation to generate a positive microalloying effect on plasticity.Based on the cooperative shear model theory,serration-flow statistics during nanoindentation loading and creep tests during the holding stage were used to analyze the influence of hydrogen on the behavior of flow units in BMGs.Experimental observations showed that the hydrogen in the Zr_(55)Cu_(30)Ni_(5)Al_(10)BMGs caused mechanical softening,plasticity improvement,and structural relaxation.Analysis also showed that the average volume,size,and activation energy of internal flow units in the BMGs all increased as a result of the increase in the hydrogen content.The hydrogenation in the BMGs was found to lead to a prolifera-tion of shear bands,which promoted plasticity.The aggregation of these internal flow units reduced the stress required for plastic deformation through shear bands,ultimately causing softening and structural relaxation. | Fuyu Dong Yuexin Chu Mengyuan He Yue Zhang Weidong Li Peter K.Liaw Binbin Wang Liangshun Luo Yanqing Su Robert O.Ritchie Xiaoguang Yuan | 2022 | Journal of Materials Science & Technology2022，，7： | 0 |
| 15 | Ultrastructural localization of active genes in Allium cepa cells显示文摘By using the anti-RNA/DNA hybrid antibody as the probe, we labeled and analyzed the precise transcrip-tional sites of active genes in Allium cepa cells in situ. The results showed that the location of labeled signals appeared in mitochondrion was the same as that in chloroplast, generally concentrated at the central matrix space where there were no cristae and thylakoids. In the extranucleolar regions of nucleus, the labeled signals of transcriptional sites were situated at the perichromatin fibrils, which decondensed and stretched out from the chromosome territories. Our results also displayed the concentrations of labeled signals in a certain region of nucleus, and this means that the gene transcription rich region actually existed in Allium cepa cells. In nucleolus, the synthetic sites of rRNA were localized not only to the periphery of fibrillar centers but also to the DFC near FC. | TAO Wei HE Mengyuan HAO Shui | 2001 | Chinese Science Bulletin2001，46，11： | 0 |
| 16 | Population genetics and forensic efficiency of 30 InDel markers in four Chinese ethnic groups residing in Sichuan显示文摘Sichuan Province is located at the transitional junction regions of the Qinghai-Tibet Plateau and the low-altitude plains.It also serves as the corridor of Sino Tibetan-speaking population migration and expansion since neolithic expansion of Proto-Tibeto-Burman populations from Middle/Upper Yellow River during Majiayao period(3300-2000 BC).However,the population structure and the corresponding genetic diversity of forensic-related markers in this region remain unclear.Thus,we genotyped 30 insertion-deletion(InDel)markers in 444 samples from four ethnic groups(Han,Tibetan,Hui and Yi)from Sichuan Province using the Investigator■ DIPplex kit to explore the characteristics of population genetics and forensic genetic focuses.All the loci were found to be in Hardy-Weinberg Equlibrium(HWE)after applying a Bonferroni correction and no pairwise loci showed prominent linkage disequilibrium.The combined matching probability(CMP)and the combined power of discrimination(CPD)are larger than 1.8089×10^(11)and 0.9999999995,respectively.Principal component analysis,multi-dimen-sional scaling plots and Neighbour-Joining tree among 65 worldwide populations indicated that Sichuan Hui and Han are genetically close to Hmong-Mien and Tai-Kadai-speaking popula-tions,and Sichuan Tibetan and Yi bear a strong genetic affinity with Tibeto-Burman-speaking populations.The model-based genetic structure further supports the genetic affinity between the studied populations and linguistically close populations. | Fei Wang Guanglin He Zheng Wang Mengge Wang Jing Liu Xing Zou Shouyu Wang Mengyuan Song Ziwei Ye Mingkun Xie Yiping Hou | 2022 | Forensic Sciences Research2022，7，3： | 0 |
| 17 | Poly(lactic acid)-aspirin microspheres prepared via the traditional and improved solvent evaporation methods and its application performances显示文摘Drug-loaded microspheres are significant for the development of modern pharmaceutical products. It is well known that the taken of aspirin for long-term increases the risk of serious gastrointestinal complications, therefore a controllable delivery of aspirin is of importance to lighten those side effects. In this work, poly(lactic acid)(PLA) was chosen as the carrier to prepare PLA-aspirin microspheres by using the traditional and the improved solvent evaporation methods. It was found that no matter which experimental condition was, the encapsulation efficiency of aspirin was higher by using the improved method than that of the traditional method. Specifically, when the concentration of polyvinyl alcohol = 1%(mass),the polymer concentration = 1:20, the oil/water rate = 1:2.5, PLA-aspirin microspheres were obtained via the improved method with a high yield of 82.83%(mass) and an encapsulation efficiency of 44.09%. PLAaspirin microspheres were then prepared continuously using the improved method, which further enhanced the encapsulation efficiency to 54.56%. Approximate 85% aspirin released from microspheres within 7 days. Obvious degradation which was represented by reduction on hardness was observed by soaking microspheres in PBS for 60 days. This work is of interest because it provides a continuous route to prepare PLA-aspirin microspheres continuously with a high drug encapsulation efficiency. | Xiaolin Pan Mengyuan Gao Yun Wang Yanping He Tian Si Yanlin Sun | 2023 | Chinese Journal of Chemical Engineering2023，60，8： | 0 |
| 18 | Application of Ultimate Oncoplastic Surgery in Breast-Conserving Surgery显示文摘Objective To investigate the application of oncoplastic surgery in breast-conserving surgery.Methods We retrospectively analyzed the clinical data of 103 breast cancer patients who underwent breast-conserving surgery in the First Affiliated Hospital of Henan University.All the patients were female whose tumor volume-to-breast volume ratio was greater than 20%.Fifty-two patients were treated with oncoplastic breast-conversing surgery(observation group),and 51 patients were treated with traditional breast-conserving surgery(control group).The volume of resected tissue,subjective satisfaction with breast shape,objective score of breast shape,and follow-up were compared between the two groups.Results In the observation group,the weight of resected breast tissue was 64.2–172.1 g,with a median of 98.7 g.In the control group,the weight of resected breast tissue was 67.5–175.7 g,with a median of 102.3 g.After 12 months of follow-up,the subjective satisfaction rate and objective score of breast shape in the observation group were significantly better than those in the traditional breast-conserving surgery group(P<0.05).There was no recurrence,metastasis,or death in the two groups.There was no significant difference in postoperative complications between the two groups(P>0.05).Conclusion Oncoplastic breast-conserving surgery leads to better cosmetic results and a more satisfactory clinical results. | Zhiqiang MA Mengyuan CHEN Haibin WU Jianxin HE Ruonan WANG Wei GUO Wensheng WANG | 2020 | Chinese Journal Of Plastic and Reconstructive Surgery2020，2，3： | 0 |
| 19 | CORRECTION:Correction to:Discrimination of False Negative Results in RT-PCR Detection of SARS-CoV-2 RNAs in Clinical Specimens by Using an Internal Reference显示文摘In the original version of Fig.41 and 4J,the cutoff lines were accidently shifted during figure layout.Figures 41 and 4J are re-drawn and provided below. | Yafei Zhang Changtai Wang Mingfeng Han Jun Ye Yong Gao Zhongping Liu Tengfei He Tuantuan Li Mengyuan Xu Luping Zhou Guizhou Zou Mengji Lu Zhenhua Zhang | 2020 | Virologica Sinica2020，35，6： | 0 |
| 20 | Antimicrobial activities and analysis of the crude extract,fractions and compounds from the Lomatogonium rotatum显示文摘This study was evaluated the antimicrobial activities of the crude extract,different fractions,and compounds from the plant of Lomatogonium carinthiacum.The fractions of chloroform and compounds 5,2 and 6 exhibited stronger antimicrobial activities.Compound 5 was the most active while Staphylococcus aureus and Candida albicans were sensitive to all the tested compounds.The existence of a relationship between the xanthone structures and inhibition of microorganism activity.The antimicrobial activity of this plant was reported here firstly.The results provided evidence that the studied plant extract,fractions as well as some of the isolated compounds might be potential sources of new antimicrobial drug. | Ruoning Wang Qin He Qingdi Mu Mengyuan Tan Jing Wang Chongning Lv Hang He Jincai Lu Lingyun Jia | 2020 | Asian Journal of Traditional Medicines2020，15，4： | 0 |
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