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| 1 | Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection显示文摘It has been known that,the novel coronavirus,2019-nCoV,which is considered similar to SARS-CoV,invades human cells via the receptor angiotensin converting enzyme II(ACE2).Moreover,lung cells that have ACE2 expression may be the main target cells during 2019-nCoV infection.However,some patients also exhibit non-respiratory symptoms,such as kidney failure,implying that 2019-nCoV could also invade other organs.To construct a risk map of different human organs,we analyzed the single-cell RNA sequencing(scRNA-seq)datasets derived from major human physiological systems,including the respiratory,cardiovascular,digestive,and urinary systems.Through scRNA-seq data analyses,we identified the organs at risk,such as lung,heart,esophagus,kidney,bladder,and ileum,and located specific cell types(i.e.,type II alveolar cells(AT2),myocardial cells,proximal tubule cells of the kidney,ileum and esophagus epithelial cells,and bladder urothelial cells),which are vulnerable to 2019-nCoV infection.Based on the findings,we constructed a risk map indicating the vulnerability of different organs to 2019-nCoV infection.This study may provide potential clues for further investigation of the pathogenesis and route of 2019-nCoV infection. | Xin Zou Ke Chen Jiawei Zou Peiyi Han Jie Hao Zeguang Han | 2020 | Frontiers of Medicine2020，14，2： | 193 |
| 2 | A bioinspired high-modulus mineral hydrogel binder for improving the cycling stability of microsized silicon particle-based lithium-ion battery显示文摘Silicon with high specific capacity is deemed an ideal anode material for lithium ion batteries,which,however suffers from low cycling life due to its dramatic volume changes.Water-soluble polymer binders recently gain increasing attention by providing an eco-friendly and low-cost way in improving the cycling stability of Si-based anodes.Herein,a novel bioinspired supramolecular mineral hydrogel binder consisting of polyacrylic acid (PAA) physically crosslinked with amorphous calcium carbonate (ACC) nanoparticles is designed for high-performance anodes made from low-cost microsized Si particles.Owing to its organic-inorganic hydrophilic nature,ACC-PAA hybrid binder exhibits the reported highest modulus (~22 GPa) for polymer binders in electrolyte,even higher than lithiated Si species (Li15Si4,~12 GPa).Together with its excellent adhesion and electrochemical stability,ACC-PAA binder can effectively suppress the pulverization of Si particles and maintain the mechanical integrity of electrodes during cycling.Therefore,even with a low binder content,the anode still shows an initial discharge capacity of 2,973 mAh·g^-1 and Coulombic efficiency of 81.5%,and retains 75% at a current density of 600 mA·g^-1 after 100 cycles.The present organic-inorganic hybrid mineral binder may open a new approach for designing more effective polymer binders for Si-based lithium-ion batteries. | Meng Tian Xiao Chen Shengtong Sun Dong Yang Peiyi Wu | 2019 | Nano Research2019，12，5： | 9 |
| 3 | Climate change and its effect on reference crop evapotranspiration in central and western Inner Mongolia during 1961-2009显示文摘水资源是到在中央、西方的内部蒙古的农业生产的主要限制之一,在的地方由干旱、半干旱的气候是特征的。参考庄稼土壤水分蒸发蒸腾损失总量(et 0 ) 是在农业生态系统的水周期的重要部分,它在庄稼生长和产量上有直接效果。et 0 上的气候变化的含意具有为关于安排的水管理和灌溉的农业的高重要性。这研究的目的是在时期上在在中央、西方的内部蒙古的 et 0 上在气候和它的效果分析变化 1961 ~ 2009。为这个目的,在越过学习区域的十个气象学的车站的数据被收集, FAO Penman-Monteith 56 方法被使用。结果证明平均温度,最大的温度和最小的温度由 0.49 莬增加了吗?? | Di HE Yaling LIU Zhihua PAN Pingli AN Liwei WANG Zhiqiang DONG Jingting ZHANG Xuebiao PAN Peiyi ZHAO | 2013 | Frontiers of Earth Science2013，7，4： | 8 |
| 4 | Preparation and Applications of Soybean Residue CNF Films显示文摘In this study, soybean residues were treated with HCl and soybean residue cellulose was extracted, which was used to prepare cellulose nanofiber (CNF) using the high-pressure homogenization method. The maximum yield of CNF, the reaction temperature, reaction time, and HCl concentration were optimized. The optimum HCl concentration for acid treatment was 6%, the reaction time was 60 min, the reaction temperature was 80℃, and the maximum yield of soybean residue cellulose was 78.8%. The different CNF films were then prepared;the color, mechanical property, and light transmittance of the CNF films were studied. Compared to the properties of the CNF film prepared with the soybean residue cellulose by high-pressure homogenization 15 times (HGT-15 film), the mechanical properties of the CNF film with soybean residue cellulose by decolorizing treatment decreased, but the light transmittance increased. The film prepared by adding HGT- 15 CNF to whey protein was investigated for its mechanical property, light transmittance, and solubility. Unlike the pure whey protein film, addition of 2.0% CNF to the whey protein enhanced the mechanical property and water vapor transmission rate (WVT) of the film. With the increase in CNF content, the solubility of the whey protein film decreased, and then stabilized. | Peiyi Li Hezhen Liu Qingqing Hou Yumeng Wang Xinping Li | 2019 | Paper And Biomaterials2019，4，3： | 7 |
| 5 | Preparation and Properties of Nanocellulose/Sodium Alginate Composite Hydrogel显示文摘Cellulose nanofiber(CNF)was isolated from Okara using deep eutectic solvent(DES)with high-speed stirring.The composite hydrogels obtained by using different proportions of CNF and sodium alginate(SA)had different properties.The CNF/SA composite hydrogels were analyzed using Fourier transform infrared spectroscopy and scanning electron microscopy and tested for compression properties,rheological properties,water content,and swelling degree.Physical crosslinking between SA and Ca^(2+),and different degrees of hydrogen bond formation between SA and CNF were observed.The CNF/SA composite hydrogel have great potential as reinforcements in eco-friendly composite hydrogels for diverse applications. | Peiyi Li Ruiyan Liu Haozhe Lei Miaomiao Zhou Boxing Jian Xinping Li | 2021 | Paper And Biomaterials2021，6，4： | 4 |
| 6 | Association of TNF-α promoter polymorphisms with the outcome of persistent HBV infection in a northeast Chinese Han population显示文摘肿瘤坏死因素 --(TNF-) 在致病和长期的肝炎 B 的临床的结果起一个重要作用病毒(HBV ) 感染。这研究的目的是在一张东北汉语汉人口评估在 TNF- 的功能的多型性和坚持的 HBV 感染的不同结果之间的关系。这里, 189 HBV 自发地恢复了题目(SR ) ,包括 180 长期的肝炎 B (CHB ) 的 571 个感染 HBV 的病人, 196 肝肝硬化(LC ) ,和 195 hepatocellular 癌(HCC ) 个人在这研究被注册。所有样品用聚合酶链反应限制碎片长度多型性方法是为 TNF- 857C/T 和 863C/A 的 genotyped。857CC 遗传型的频率与 SR 题目的相比在 CHB 和 LC 个人是显著地更高的(P= 0.03,或 = 1.57, 95% CI 1.042.39 和 P= 0.03,或 = 1.57, 95% CI 1.042.35,分别地) 。在等位基因 857C 的分发的重要差别为 CHB 对 SR 被观察(P= 0.01,或 = 1.52, 95% CI 1.082.13 ) 并且 LC 对 SR (P= 0.02,或 = 1.47, 95% CI 1.062.04 ) 队。另外, 863AA 遗传型的频率比 SR 题目的在 CHB 和 LC 病人是显著地更高的( P= 0.01 ,或= 3.90 ,95% CI 1.3511.23 和 P= 0.01 ,或= 3.83 ,95% CI 1.3410.96 ,分别地),并且等位基因 863A 频率是显著地在比 SR 控制的 CHB , LC ,和 HCC 队更普通( P= 0.004 ,或= 1.72 ,95% CI 1.192.50 ;P= 0.001,或 = 1.81, 95% CI 1.262.61 和 P= 0.001,或 = 1.90, 95% CI 1.332.73,分别地) 。我们的数据也表明 haplotype CA 强烈与坚持的 HBV 感染被联系。这些结果在学习人口建议在 TNF- 倡导者变体和坚持的 HBV 感染的不同结果之间的一个协会。 | Bing Qiui Xi Wang Peiyi Zhang Chunlin Shi Jiye Zhang Wenliang Qiu Wenduo Wang Dongfu Li | 2012 | Acta Biochimica et Biophysica Sinica2012，44，8： | 4 |
| 7 | Environmental magnetic comparisons between distal and proximal sediments of Huangqihai Lake,Inner Mongolia,China显示文摘Spatial variations in lake sediments are a product of their depositional heterogeneities.To better correlate synchronous strata in Huangqihai Lake,two sections were excavated from the lake-center and the lake-shore.The study involved detailed lithology,mineralogy,and rock magnetic analysis.The results show that the frequency-dependent susceptibility,which is related to the content of super-paramagnetic minerals,is relatively easy to contrast between the two sections.However,mass susceptibility and saturation isothermal remanence,which are related to the content of total magnetic minerals,are difficult to contrast.A possible reason for this difference is that small-particle super-paramagnetic minerals are formed mainly during pedogenic processes,which correlates well with climate change and avoids the effects of local factors when corrections are made at the whole-lake scale.Both sections can be divided into three stages,which appear to be well correlated with previous results obtained through other environmental proxies. | DONG Jin WANG Yong ZHANG ShiHong CHI ZhenQing YAO PeiYi ZHAO ZhiLi | 2012 | Science China Earth Sciences2012，55，9： | 4 |
| 8 | Differences in atheroma between Caucasian and Asian subjects with anterior stroke:A vessel wall MRI study显示文摘Background and purpose While extracranial carotid artery stenosis is more common among Caucasians and intracranial artery stenosis is more common among Asians,the differences in atherosclerotic plaque characteristics have not yet been extensively examined.We sought to investigate plaque location and characteristics within extracranial carotid and intracranial arteries in symptomatic Caucasians and Chinese using vessel wall MRI.Methods Subjects with recent anterior circulation ischaemic stroke were recruited and imaged at two sites in the USA and China using similar protocols.Both extracranial carotid and intracranial arteries were reviewed to determine plaque location and characteristics.Results The prevalence of extracranial carotid plaque in Caucasians and Chinese was 73.1%and 49.1%,respectively(p=0.055).Prevalence of intracranial plaque was 38.5%and 69.1%in Caucasians and Chinese,respectively(p=0.02).Furthermore,42% of Caucasians and 16%of Chinese had high-risk plaque(HRP)features(intraplaque haemorrhage,luminal surface disruption)in the extracranial carotid artery(p=0.03).The prevalence of HRP features in intracranial arteries was not significantly different between the two cohorts(4%vs 11%;p=0.42).Conclusions Differences in the location and characteristics of cerebrovascular atherosclerosis were identified by vessel wall MRI in US Caucasian and Chinese subjects with recent anterior circulation ischaemic stroke.Extracranial carotid plaques with HRP features were more common in Caucasians.Intracranial plaques were more common in Chinese subjects,but no significant difference between the two cohorts in intracranial HRP prevalence was found.Larger studies using vessel wall imaging to investigate racial differences in cerebrovascular disease may inform underlying mechanisms of HRP development and may ultimately help guide appropriate therapy. | Hiroko Watase Mi Shen Binbin Sui Peiyi Gao Dong Zhang Jie Sun Niranjan Balu Daniel S Hippe Gail P Jarvik Xihai Zhao Rui Li Shuo Chen Chun Yuan Thomas S Hatsukami | 2021 | Stroke & Vascular Neurology2021，6，1： | 4 |
| 9 | Effect of High Pressure Homogenization Treatment on Structure and Properties of Soybean Residue Cellulose Nanofibers显示文摘To reduce the adverse effects of non-cellulose materials on subsequent homogenization,the effects of a high-pressure homogenization treatment on the structure and properties of cellulose nanofibers(CNF)prepared by acid treatment of soybean residue were studied.The effects of the number of homogenization step on the microfibrillation degree,crystalline structure and mechanical properties of the soybean residue were analyzed by SEM,FT-IR,XRD,TG and DTG.The results showed that an increase in the number of homogenization steps led to an increase in the degree of microfibrillation,a more uniform distribution of the CNF diameter,and an increase in the crystallinity of CNF.However,but when the number of homogenization steps exceeded 15,the rate of change decreased,and the crystallinity of CNF decreased.As the number of homogenization steps increased,the average degree of polymerization and average molecular weight of CNF decreased continuously,and after 15 homogenization steps,their rate of change also decreased.Therefore,15 steps of high-pressure homogenization represented a suitable number of steps to prepare the soybean residue CNF with an average diameter of 15 nm. | Peiyi Li Yumeng Wang Binyao Zhou Qingqing Hou Hezhen Liu Haozhe Lei Boxing Jian Xinping Li | 2019 | Paper And Biomaterials2019，4，4： | 4 |
| 10 | Interfacially stable MOF nanosheet membrane with tailored nanochannels for ultrafast and thermo-responsive nanofiltration显示文摘Two-dimensional nanosheet membranes with responsive nanochannels are appealing for controlled mass transfer/separation,but limited by everchanging thicknesses arising from unstable interfaces.Herein,an interfacially stable,thermo-responsive nanosheet membrane is assembled from twin-chain stabilized metal-organic framework(MOF)nanosheets,which function via two cyclic amide-bearing polymers,thermo-responsive poly(N-vinyl caprolactam)(PVCL)for adjusting channel size,and non-responsive polyvinylpyrrolidone for supporting constant interlayer distance.Owing to the microporosity of MOF nanosheets and controllable interface wettability,the hybrid membrane demonstrates both superior separation performance and stable thermo-responsiveness.Scattering and correlation spectroscopic analyses further corroborate the respective roles of the two polymers and reveal the microenvironment changes of nanochannels are motivated by the dehydration of PVCL chains. | Wei Jia Baohu Wu Shengtong Sun Peiyi Wu | 2020 | Nano Research2020，13，11： | 3 |
| 11 | Alternate binding modes of anti-CRISPR viral suppressors AcrF1/2 to Csy surveillance complex revealed by cryo-EM structures显示文摘抗菌素编码 anti-CRISPR suppressors 抵抗他们的细菌的主人的 CRISPR/Cas 免疫,因此便于他们的幸存和复制。以前的研究显示出那二编码噬菌体的 anti-CRISPR 蛋白质, AcrF1 和 AcrF2,如果由由 Csy 监视建筑群阻止目标 DNA 识别的 Pseudomonas aeruginosa 的 CRISPR/Cas 系统,而是精确位于下面机制是未知的,压制类型。这里我们在场 Csy 建筑群一定的 AcrF1/2 的结构由 cryo 他们决定了单个粒子的重建。由结构的分析,我们发现 AcrF1 由防碍在 DNA 目标海滨和 crRNA 分隔符之间的基础配对禁止 Csy 建筑群的目标 DNA 识别。另外,当个别地工作或与 AcrF2 合作时, AcrF1 的多重拷贝与不同模式绑在 Csy 建筑群,它可能排除通过不同机制有约束力的目标 DNA。和以前的报告,我们为二 anti-CRISPR suppressors, AcrF1 和 AcrF2 提供一种全面工作情形,它由指向 Csy 监视建筑群的沉默 CRISPR/Cas 免疫。 | Ruchao Peng Ying Xu Tengfei Zhu Ningning Li Jianxun Qi Yan Chai Min Wu Xinzheng Zhang Yi Shi Peiyi Wang Jiawei Wang Ning Gao George Fu Gao | 2017 | Cell Research2017，27，7： | 3 |
| 12 | An Edge-Boxes-Based Intruder Detection Algorithm for UAV Sense and Avoid System显示文摘With the great development of unmanned aircraft system(UAS)over the last decade,sense and avoid(SAA)system has been a crucial technology for integrating unmanned aircraft vehicle(UAV)into national airspace with reliable and safe operations.This paper mainly focuses on intruder detection for SAA system.A robust algorithm based on the combination of edge-boxes and spatial pyramid matching using sparse coding(sc-SPM)is presented.The algorithm is composed of three stages.First,edge-boxes method is adopted to obtain a large number of proposals;Second,the optimization program is presented to obtain intruder area-of-interest(ROI)regions;Third,sc-SPM is employed for feature representation of ROI regions and support vector machines(SVM)is adopted to detect the intruder.The algorithm is evaluated under different weather conditions.The recall reaches to 0.95 in dawn and sunny weather and 0.9 in cloudy weather.The experimental results indicate that the intruder detection algorithm is effective and robust with various weather under complex background. | ZHANG Zhouyu CAO Yunfeng ZHONG Peiyi DING Meng HU Yunqiang | 2019 | Transactions of Nanjing University of Aeronautics and Astronautics2019，36，2： | 3 |
| 13 | Prediction of radiosensitivity in primary central nervous system germ cell tumors using dynamic contrast-enhanced magnetic resonance imaging显示文摘Objective: To evaluate the feasibility of dynamic contrast-enhanced magnetic resonance imaging(DCEMRI) for predicting tumor response to radiotherapy in patients with suspected primary central nervous system(CNS) germ cell tumors(GCTs).Methods: DCE-MRI parameters of 35 patients with suspected primary CNS GCTs were obtained prior to diagnostic radiation, using the Tofts and Kermode model. Radiosensitivity was determined in tumors diagnosed 2 weeks after radiation by observing changes in tumor size and markers as a response to MRI. Taking radiosensitivity as the gold standard, the cut-off value of DCE-MRI parameters was measured by receiver operating characteristic(ROC) curve. Diagnostic accuracy of DCE-MRI parameters for predicting radiosensitivity was evaluated by ROC curve.Results: A significant elevation in transfer constant(Ktrans) and extravascular extracellular space(Ve)(P=0.000), as well as a significant reduction in rate constant(Kep)(P=0.000) was observed in tumors. Ktrans, relative Ktrans, and relative Kep of the responsive group were significantly higher than non-responsive groups. No significant difference was found in Kep, Ve, and relative Ve between the two groups. Relative Ktrans showed the best diagnostic value in predicting radiosensitivity with a sensitivity of 100%, specificity of 91.7%, positive predictive value(PPV) of 95.8%, and negative predictive value(NPV) of 100%.Conclusions: Relative Ktrans appeared promising in predicting tumor response to radiation therapy(RT). It is implied that DCE-MRI pre-treatment is a requisite step in diagnostic procedures and a novel and reliable approach to guide clinical choice of RT. | Chenlu Feng Peiyi Gao Xiaoguang Qiu Tianyi Qian Yan Lin Jian Zhou Binbin Sui | 2015 | Chinese Journal of Cancer Research2015，27，3： | 3 |
| 14 | Construction of the Chinese Veteran Clinical Research (CVCR) Platform for the assessment of non-communicable diseases显示文摘 | Tan Jiping Li Nan Gao Jing Guo Yuhe Hu Wei Yang Jinsheng Yu Baocheng Yu Jianmin Du Wei Zhang Wenjun Cui Lianqi Wang Qingsong Xia Xiangnan Li Jianjun Zhou Peiyi Zhang Baohe Liu Zhiying Zhang Shaogang Sun Lanying Liu Nan Deng Ruixiang Dai Wenguang Yi Fang Chen Wenjun Zhang Yongqing Xue Shenwu Cui Bo Zhao Yiming Wang Luning | 2014 | Chinese Medical Journal2014，，3： | 3 |
| 15 | Resistance switching for RRAM applications显示文摘Resistive random access memory (RRAM or ReRAM) is a non-volatile memory (NVM) technology that consumes minimal energy while offering sub-nanosecond switching. In addition, the data stability against high temperature and cycling wear is very robust, allowing new NVM applications in a variety of markets (au- tomotive, embedded, storage, RAM). Based on sudden conduction through oxide insulators, the characteristics of RRAM technology have still yet to be fully described. In this paper, we present our current understanding of this very promising technology. | CHEN Frederick T LEE HengYuan CHEN YuSheng HSU YenYa ZHANG LiJie CHEN PangShiu CHEN WeiSu GU PeiYi LIU WenHsing WANG SuMin TSAI ChenHan SHEU ShyhShyuan TSAI MingJinn HUANG Ru | 2011 | Science China(Information Sciences)2011，54，5： | 3 |
| 16 | Nafion-assisted exfoliation of MoS2 in water phase and the application in quick-response NIR light controllable multi-shape memory membrane显示文摘 | Wei Jia Beibei Tang Peiyi Wu | 2018 | Nano Research2018，11，1： | 3 |
| 17 | Positive influence of the scattering medium on reflective ghost imaging显示文摘The scattering medium is usually thought to have a negative effect on the imaging process.In this paper,it is shown that the imaging quality of reflective ghost imaging(GI)in the scattering medium can be improved effectively when the binary method is used.By the experimental and the numerical results,it is proved that the existence of the scattering medium is just the cause of this phenomenon,i.e.,the scattering medium has a positive effect on the imaging quality of reflective GI.During this process,the effect from the scattering medium behaves as the random noise which makes the imaging quality of binary ghost imaging have an obvious improvement. | QIN FU YANFENG BAI XIANWEI HUANG SUQIN NAN PEIYI XIE XIQUAN FU | 2019 | Photonics Research2019，7，12： | 3 |
| 18 | Facile Synthesis of NiFe_2O_4/Reduced Graphene Oxide Hybrid with Enhanced Electrochemical Lithium Storage Performance显示文摘In this work, a facile, one-pot route has been applied to synthesize nanohybrids based on mixed oxide Ni Fe2O4 and reduced graphene oxide(r GO). The hybrid is constructed by nanosized Ni Fe2O4 crystals confined by fewlayered r GO sheets. The formation mechanism and microstructure of the hybrids have been clarified by X-ray diffraction, Raman spectroscopy, scanning electron microscopy, and transmission electron microscopy.Electrochemical tests show that the performance of Ni Fe2O4 can be considerably improved by r GO incorporation. The performance improvement can be attributed to the two-dimensional conductive channels and the unique hybrid structure r GO constructed. The easy synthesis and good electrochemical performance of Ni Fe2O4/r GO hybrid make it a promising anode material for Li-ion batteries. | Peiyi Zhu Shuangyu Liu Jian Xie Shichao Zhang Gaoshao Cao Xinbing Zhao | 2014 | Journal of Materials Science & Technology2014，30，11： | 2 |
| 19 | Mechanoadaptive morphing gel electrolyte enables flexible and fast-charging Zn-ion batteries with outstanding dendrite suppression performance显示文摘The safe,flexible,and environment-friendly Zn-ion batteries have aroused great interests nowadays.Nevertheless,flagrant Zn dendrite uncontrollably grows in liquid electrolytes due to insufficient surface protection,which severely impedes the future applications of Zn-ion batteries especially at high current densities.Gel electrolytes are emerging to tackle this issue,yet the required high modulus for inhibiting dendrite growth as well as concurrent poor interfacial contact with roughened Zn electrodes are not easily reconcilable to regulate the fragile Zn/Zn^(2+) interface.Here we demonstrate,such a conflict may be defeated by using a mechanoadaptive cellulose nanofibril-based morphing gel electrolyte(MorphGE),which synergizes bulk compliance for optimizing interfacial contact as well as high modulus for suppressing dendrite formation.Moreover,by anchoring desolvated Zn^(2+) on cellulose nanofibrils,the side reactions which induce dendrite formation are also significantly reduced.As a result,the MorphGE-based symmetrical Zn-ion battery demonstrated outstanding stability for more than 100 h at the high current density of 10 mA·cm^(−2) and areal capacity of 10 mA·h·cm^(−2),and the corresponding Zn-ion battery delivered a prominent specific capacity of 100 mA·h·g^(−1) for more than 500 cycles at 20 C.The present example of engineering the mechanoadaptivity of gel electrolytes will shed light on a new pathway for designing highly safe and flexible energy storage devices. | Faqing Cao Baohu Wu Tianyu Li Shengtong Sun Yucong Jiao Peiyi Wu | 2022 | Nano Research2022，15，3： | 2 |
| 20 | Near-atomic structure of the inner ring of the Saccharomyces cerevisiae nuclear pore complex显示文摘Nuclear pore complexes(NPCs)mediate bidirectional nucleocytoplasmic transport of substances in eukaryotic cells.However,the accurate molecular arrangement of NPCs remains enigmatic owing to their huge size and highly dynamic nature.Here we determined the structure of the asymmetric unit of the inner ring(IR monomer)at 3.73Åresolution by single-particle cryo-electron microscopy,and created an atomic model of the intact IR consisting of 192 molecules of 8 nucleoporins.In each IR monomer,the Z-shaped Nup188–Nup192 complex in the middle layer is sandwiched by two approximately parallel rhomboidal structures in the inner and outer layers,while Nup188,Nup192 and Nic96 link all subunits to constitute a relatively stable IR monomer.In contrast,the intact IR is assembled by loose and instable interactions between IR monomers.These structures,together with previously reported structural information of IR,reveal two distinct interaction modes between IR monomers and extensive flexible connections in IR assembly,providing a structural basis for the stability and malleability of IR. | Zongqiang Li Shuaijiabin Chen Liang Zhao Guoqiang Huang Xiong Pi Shan Sun Peiyi Wang Sen-Fang Sui | 2022 | Cell Research2022，32，5： | 2 |
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