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| 1 | Land Use Effects on Soil Organic Carbon, Microbial Biomass and Microbial Activity in Changbai Mountains of Northeast China显示文摘Land use changes are known to alter soil organic carbon(SOC) and microbial properties, however, information about how conversion of natural forest to agricultural land use as well as plantations affects SOC and microbial properties in the Changbai Mountains of Northeast China is meager. Soil carbon content, microbial biomass carbon(MBC), basal respiration and soil carbon mineralization were studied in five selected types of land use: natural old-growth broad-leaved Korean pine mixed forest(NF); spruce plantation(SP) established following clear-cutting of NF; cropland(CL); ginseng farmland(GF) previously under NF; and a five-year Mongolian oak young forest(YF) reforested on an abandoned GF, in the Changbai Mountains of Northeast China in 2011. Results showed that SOC content was significantly lower in SP, CL, GF, and YF than in NF. MBC ranged from 304.4 mg/kg in CL to 1350.3 mg/kg in NF, which was significantly higher in the soil of NF than any soil of the other four land use types. The SOC and MBC contents were higher in SP soil than in CL, GF, and YF soils, yielding a significant difference between SP and CL. The value of basal respiration was also higher in NF than in SP, CL, GF, and YF. Simultaneously, higher values of the metabolic quotient were detected in CL, GF, and YF soils, indicating low substrate utilization of the soil microbial community compared with that in NF and SP soil. The values of cumulative mineralized carbon and potentially mineralized carbon(C0) in NF were significantly higher than those in CL and GF, while no significant difference was observed between NF and SP. In addition, YF had higher values of C0 and C mineralization rate compared with GF. The results indicate that conversion from NF into agricultural land(CL and GF) uses and plantation may lead to a reduction in soil nutrients(SOC and MBC) and substrate utilization efficiency of the microbial community. By contrast, soils below SP were more conducive to the preservation of soil organic matter, which was reflected in the comparison of microbial indicators among CL, GF, and YF land uses. This study can provide data for evaluating soils nutrients under different land use types, and serve as references for the rational land use of natural forest in the study area. | FANG Xiangmin WANG Qingli ZHOU Wangming ZHAO Wei WEI Yawei NIU Lijun DAI Limin | 2014 | Chinese Geographical Science2014，24，3： | 16 |
| 2 | Comparison of effect of granules and herbs of Bu-Shen-Yi-Qi-Tang on airway inflammation in asthmatic mice显示文摘 | Wei Ying Lyu Yubao Li Mihui Luo Qingli Sun Jing Liu Feng Lin Yanhua Chen Meixia Mammat Nurahmat Muhammadian Abduwaki Dong Jingcheng | 2014 | Chinese Medical Journal2014，，22： | 3 |
| 3 | Compatibility Evaluation between Direct Coal Liquefaction Residue and Bitumen显示文摘The compatibility between direct coal liquefaction residue(DCLR) and five kinds of pure bitumen(Shell-90,SK-90, ZSY-70, DM-70 and KLMY-50) was evaluated in this study. The rheological characteristics, glass transition temperatures(T_g), solubility parameters(SP) and SARA(saturates, aromatics, resins, and asphaltenes) fractions of DCLR,five kinds of pure bitumen and their blends(named as DCLR modified bitumen) were measured using the dynamic shear rheometer(DSR), differential scanning calorimetry(DSC), viscosity, and SARA tests, respectively. And the compatibility between DCLR and pure bitumen was characterized with three approaches, viz. the Cole-Cole plot,T_g, and the solubility parameter difference(SPD) method. Since each method has its own working mechanism, the compatibility ranking for the DCLR and five kinds of pure bitumen is slightly different according to the three approaches. However, the difference is pretty close and sometimes can be ignored. The general compatibility ranking decreases in the following order: Shell-90≈SK-90>DM-70≈ZSY-70>KLMY-50, which is affected by the asphaltenes content and the colloid index(I_c) value in the pure bitumen. Pure bitumen with lower asphaltenes content and colloid index(I_c) value has better compatibility with DCLR. | Ji Jie Wu Hao Xu Ying Suo Zhi Wei Jianming Dai Qingli Zhang Ran Diab Aboelkasim | 2019 | China Petroleum Processing & Petrochemical Technology2019，21，1： | 2 |
| 4 | Superior performance of a 2 kHz pulse Nd:YAG laser based on a gradient-doped crystal显示文摘Herein,we report a homemade new Nd:YAG crystal rod that contains a gradient dopant of 0.39–0.80 at.%Nd3+ from end to end,achieving superior performance of a 2 kHz Nd:YAG pulse laser at 1064 nm. The optical-tooptical conversion efficiency reached 53.8%,and the maximum output power of the laser was 24.2 W,enhanced by 35.9% compared with a uniform crystal rod with the same total concentration of Nd3+. Significantly,our experiments revealed that the gradient concentration crystal produced a relatively even pumping distribution along the rod axis,greatly reducing the temperature gradient as well as having a smaller thermal effect. The pump and thermal distribution smoothing obviously improved the features of laser oscillation and output. | MENG’EN WEI TINGQING CHENG RENQIN DOU QINGLI ZHANG HAIHE JIANG | 2021 | Photonics Research2021，9，7： | 1 |
| 5 | Characterization of the Azinomycin B Biosynthetic Gene Cluster Revealing a Different Iterative Type I Polyketide Synthase for Naphthoate Biosynthesis显示文摘 | Qunfei Zhao Qingli He Wei Ding Mancheng Tang Qianjin Kang Yi Yu Wei Deng Qi Zhang Jie Fang Gongli Tang Wen Liu | 2008 | Chemistry & Biology2008，，7： | 1 |
| 6 | IL-13/IL-13RA2 signaling promotes colorectal cancer stem cell tumorigenesis by inducing ubiquitinated degradation of p53显示文摘Cancer stem cells(CSCs)are considered tumor-initiating cells and the main drivers of disease progression.Targeting these rare cancer cells,however,remains challenging with respect to therapeutic benefit.Here,we report the up-regulation of IL-13RA2 expression in colorectal cancer(CRC)tissues and spheroid cells.The expression of IL-13RA2 was positively correlated with canonical stemness markers in CRC.We further demonstrated that the level of IL-13 was up-regulated in the serum of CRC patients.Biologically,recombinant IL-13(rIL13)stimulation promoted the sphere formation,proliferation,and migration of CRC cells in vitro and enhanced tumorigenesis in vivo.This phenotype could be reversed by knocking down IL-13RA2.Mechanistically,IL-13 activated autophagy by inducing LC3I/LC3II transformation in CRC-CSCs,which was crucial for the biological functions of IL-13.We further demonstrated that IL-13RA2 acted as a modular link of the E3 ligase UBE3C and the substrate p53 protein,enhancing the interaction of UBE3C and p53,thereby inducing the K48-linked ubiquitination of p53.In conclusion,the IL-13/IL-13RA2 signaling cascade promotes CRC-CSC self-renewal and tumorigenesis by inducing p53 ubiquitination,adding an important layer to the connection between IL-13 and p53,which can be translated into novel targeted therapies. | Baoyu He Jing Liang Qianqian Qin Yuqin Zhang Shuo Shi Jinghe Cao Zhixin Zhang Qingli Bie Rou Zhao Li Wei Baogui Zhang Bin Zhang | 2024 | Genes & Diseases2024，11，1： | 0 |
| 7 | Maternal genetic structure of a neolithic population of the Yangshao culture显示文摘The Yangshao culture is one of the most influential Neolithic cultures in East Asia.The populations associated with the Yangshao culture were widely distributed along the Yellow River basin and were suggested to play a profound role in the present-day East Asians.To date,the population of the Yangshao culture is largely investigated through archaeological studies. | Bo Miao Yichen Liu Wanfa Gu Qingli Wei Qian Wu Wenjun Wang Ming Zhang Manyu Ding Tianyi Wang Juncen Liu Feng Liu Peng Cao Qingyan Dai Ruowei Yang Xiaotian Feng Wanjing Ping Weihong Hou Haibing Yuan Qiaomei Fu | 2021 | Journal of Genetics and Genomics2021，48，8： | 0 |
| 8 | A novel recombinant adeno-associated virus vaccine reduces behavioral impairment and β-amyloid plaques in a mouse model of Alzheimer's disease显示文摘 | Jianmin Zhang Xiaobing Wu Chuan Qin Jin Qi Shibin Ma Huiyuan Zhang Qingli Kong Dongqing Chen Denian Ba Wei He | 2006 | 中国生物学文摘2006，20，3： | 0 |
| 9 | Tolerance and acceptance of hepatic venous pressure gradient measurement in cirrhosis(CHESS1904):An international multicenter study显示文摘Aim:To determine the tolerance and acceptance of hepatic venous pressure gradient(HVPG)measurements in patients with liver cirrhosis.Methods:This prospective international multicenter study included 271 patients with cirrhosis who were scheduled to undergo HVPG measurement between October 2019 and June 2020.Data related to the tolerance and acceptance of HVPG measurements were collected using descriptive questionnaires.Results:HVPG measurements were technically successful in all 271 patients,with 141(52.0%)undergoing HVPG measurement alone.The complication rate was 0.4%.Postoperative pain was significantly lower than preoperative expected pain(p<0.001)and intraoperative pain(p<0.001),and intraoperative pain was also significantly lower than preoperative expected pain(p=0.036).No,mild,moderate,severe,and intolerable discomfort scores were reported by 36.9%,44.6%,11.1%,6.3%,and 0.4%of these patients,respectively,during HVPG measurement and by 54.6%32.5%,11.4%,1.5%,and 0%,respectively,after HVPG measurement.Of these patients,39.5%had little understanding and 10%had no understanding of the value of HVPG measurement,with 35.1%and 4.1%regarding HVPG measurements as being of little or no help,respectively.Most patients reported that they would definitely(15.5%),probably(46.9%),or possibly(29.9%)choose to undergo additional HVPG measurements again,and 62.7%regarded the cost of the procedure as acceptable.Conclusion:HVPG measurement was safe and well‐tolerated in patients with cirrhosis,but patient education and communication are warranted to improve the acceptance of this procedure. | Jun‐Hui Sun He Zhao Haijun Zhang Lei Li NecatiÖrmeci Zi‐Niu Yu Xun Li Shuangxi Li Xujun Yang Huaping Wei Xiaoliang Zhu Zhengcong Zhang Yajin Wang Zhongwei Zhao Jianting Mao Qiaohong Wu Xiaole Sun Huiling Xiang Kefeng Jia Chao Yang Wei Wu Xiuqing Lin Haixin Yao Changzeng Zuo Jitao Wang Bo Zhang Chunqing Zhang Xiaoling Wu Guangchuan Wang Shengjuan Yao Ruihang Wang Li Zhou Hui Huan Qingli Tu Xue Pu Feng Zhang Qin Yin Linpeng Zhang Ying Guo Jian Wang Kohei Kotani Sawako Uchida‐Kobayashi Norifumi Kawada He Zhu Li Li Wei Wang Guo Zhang Lei Yu Xudong Cui Qingliang Zhu Hailong Zhang Xiaoli Hu Rafael OXimenes Adriano Gonçalves de Araújo Giulliano Gardenghi Yubao Zheng Zebin Wu Mingsheng Huang Xiaoyong Chen Jun Wu Feng Xie Yang Bo Shengjuan Hu Linke Ma Xiao Li Xiaolong Qi | 2022 | Portal Hypertension & Cirrhosis2022，1，1： | 0 |
| 10 | DNA methylation markers in the diagnosis and prognosis of common leukemias显示文摘The ability to identify a specific type of leukemia using minimally invasive biopsies holds great promise to improve the diagnosis,treatment selection,and prognosis prediction of patients.Using genome-wide methylation profiling and machine learning methods,we investigated the utility of CpG methylation status to differentiate blood from patients with acute lymphocytic leukemia(ALL)or acute myelogenous leukemia(AML)from normal blood.We established a CpG methylation panel that can distinguish ALL and AML blood from normal blood as well as ALL blood from AML blood with high sensitivity and specificity.We then developed a methylation-based survival classifier with 23 CpGs for ALL and 20 CpGs for AML that could successfully divide patients into high-risk and low-risk groups,with significant differences in clinical outcome in each leukemia type.Together,these findings demonstrate that methylation profiles can be highly sensitive and specific in the accurate diagnosis of ALL and AML,with implications for the prediction of prognosis and treatment selection. | Hua Jiang Zhiying Ou Yingyi He Meixing Yu Shaoqing Wu Gen Li Jie Zhu Ru Zhang Jiayi Wang Lianghong Zheng Xiaohong Zhang Wenge Hao Liya He Xiaoqiong Gu Qingli Quan Edward Zhang Huiyan Luo Wei Wei Zhihuan Li Guangxi Zang Charlotte Zhang Tina Poon Daniel Zhang Ian Ziyar Run-ze Zhang Oulan Li Linhai Cheng Taylor Shimizu Xinping Cui Jian-kang Zhu Xin Sun Kang Zhang | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 0 |
| 11 | Analysis on Results of Test and Supervision for Oxidative Hair Dyes Samples in Yangzhou from 2013 to 2018显示文摘According to Hygienic Standard for Cosmetics (2007 Edition) and Safety and Technical Standards for Cosmetics (2015 Edition), Oxidative Hair Dyes were supervised and inspected in Yangzhou from 2013 to 2018. P-Phenylenediamine and other 6 kinds of components from 85 batches of samples were determined and analyzed by HPLC. Only one batch of samples had not passed test, o-Phenylenediamine was detected that should be prohibited in hair dyes. The results of supervision and inspection for oxidative hair dyes were good in Yangzhou from 2013 to 2018. | Ling Zhen Ding Susu Liu Hui Yao Jingjing Zhu Qingli Wang Wei | 2019 | China Detergent & Cosmetics2019，4，2： | 0 |
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