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您的检索式：作者名="Quanhong Ping"
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| 1 | Chemotherapy initiation with single-course methotrexate alone or combined with dactinomycin versus multi-course methotrexate for low-risk gestational trophoblastic neoplasia: a multi-centric randomized clinical trial显示文摘We aimed to evaluate the effectiveness and safety of single-course initial regimens in patients with low-risk gestational trophoblastic neoplasia(GTN).In this trial (NCT01823315),276 patients were analyzed.Patients were allocated to three initiated regimens:single-course methotrexate(MTX),single-course MTX+dactinomycin(ACTD),and multi-course MTX(control arm).The primary endpoint was the complete remission(CR)rate by initial drug(s).The primary CR rate was 64.4%with multi-course MTX in the control arm.For the single-course MTX arm,the CR rate was 35.8%by one course;it increased to 59.3%after subsequent multi-course MTX,with non-inferiority to the control(difference-5.1%,95%confidence interval(CI)-19.4%to 9.2%,P=0.014).After further treatment with multi-course ACTD,the CR rate(93.3%)was similar to that of the control(95.2%,P=0.577).For the single-course MTX+ACTD arm,the CR rate was 46.7%by one course,which increased to 89.1%after subsequent multi-course,with non-inferiority(difference 24.7%,95%CI 12.8%-36.6%,P<0.001)to the control.It was similar to the CR rate by MTX and further ACTD in the control arm(89.1%vs.95.2%,P=0.135).Four patients experienced recurrence,with no death,during the 2-year follow-up.We demonstrated that chemotherapy initiation with single-course MTX may be an alternative regimen for patients with low-risk GTN. | Lili Chen Ling Xi Jie Jiang Rutie Yin Pengpeng Qu Xiuqin Li Xiaoyun Wan Yaxia Chen Dongxiao Hu Yuyan Mao Zimin Pan Xiaodong Cheng Xinyu Wang Qingli Li Danhui Weng Xi Zhang Hong Zhang Quanhong Ping Xiaomei Liu Xing Xie Beihua Kong Ding Ma Weiguo Lu | 2022 | Frontiers of Medicine2022，16，2： | 2 |
| 2 | Apoptosis induced by sonodynamic treatment by protoporphyrin IX on MDA-MB-231 cells显示文摘 | Yixiang Li Pan Wang Ping Zhao Sijia Zhu Xiaobing Wang Quanhong Liu | 2011 | Ultrasonics2011，，4： | 1 |
| 3 | Role of Autophagy in Sonodynamic Therapy-Induced Cytotoxicity in S180 Cells显示文摘 | Xiaobing Wang Quanhong Liu Zhezhi Wang Pan Wang Ping Zhao Xianghong Zhao Liang Yang Yixiang Li | 2010 | Ultrasound in Medicine & Biology2010，，11： | 1 |
| 4 | Reconstruction of surface ocean water pCO_(2(aq)) in Nansha area,the South China Sea during the last 30 ka显示文摘The reconstruction of pCO2 in the tropic ocean is one of the most important issues to understand global cli-matic changes. In this study, the high-resolution strati-graphic analysis of core 17962 was conducted, which is lo-cated in the southern South China Sea (SCS). The contents of sedimentary organic matter, the stable carbon isotopic composition of sedimentary organic matter, and the d 13C values of black carbon and terrigenous n-alkanes were de-termined. And the d 13Cwc value of carbon derived from aquatic was calculated. On the basis of d 13Corg-pCO2 equa-tion proposed by Popp et al. (1989), we estimated the pCO2 in the Nansha area, SCS, since the last glaciation using d 13Cwc instead of d 13Corg. The results show that the average pCO2 was estimated at 240 ppmV during the last glaciation, and at 320 ppmV in the Holocene. A comparison of surface sea pCO2 with the atmosphere CO2 recorded in the Vostok ice core, indicates that CO2 in surface water of the southern SCS could emit into atmosphere during the last 30 ka. | HU Jianfang JIA Guodong PENG Ping FANG Dianyong ZHAO Quanhong | 2003 | Chinese Science Bulletin2003，48，2： | 0 |
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