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| 1 | 用于轻金属切削的新工具涂层显示文摘新的碳基涂层已被发展用于切削轻金属 (如铝 )。这类涂层能直接用于工具上或者作为另一种硬质涂层的顶层。切削试验显示 :这类涂层对于容易粘附在工具上的材料 (如铝合金 )具有良好的切削性能 ,因为显著地减少了所谓的切屑瘤 (BUE)的出现。结果延长了工具的寿命并使工件材料在切削后表面光滑。特别是在干切削和深孔加工方面 ,涂层性能非常好。关于涂层性能的观察及原始切削结果将逐一介绍。本文也将介绍由一家主导欧洲的航空航天工业的制造商最近完成的工业领域的试验结果。切削力、切屑瘤的形成和表面粗糙度等数据将用来解释整个干切削过程。 | Dave Doerwald Thomas Krug Roel Tietema Wei-Ming Sim Quanshun Luo Papken Hovsepian 林松盛 代明江 | 2004 | 国外金属热处理2004，25，5： | 7 |
| 2 | The combination of chidamide with the CHOEP regimen in previously untreated patients with peripheral T-cell lymphoma: a prospective, multicenter, single arm, phase 1b/2 study显示文摘Objective:To assess the efficacy and safety of the novel histone deacetylase inhibitor,chidamide,in combination with cyclophosphamide,doxorubicin,vincristine,etoposide,and prednisone(Chi-CHOEP)for untreated peripheral T-cell lymphoma(PTCL).Methods:A prospective,multicenter,single arm,phase 1 b/2 study was conducted.A total of 128 patients with untreated PTCL(18–70 years of age)were enrolled between March 2016 and November 2019,and treated with up to 6 cycles with the Chi-CHOEP regimen.In the phase 1 b study,3 dose levels of chidamide were evaluated and the primary endpoint was determination of the maximumtolerated dose and recommended phase 2 dose(RP2 D).The primary endpoint of the phase 2 study was 2-year progression-free survival(PFS).Results:Fifteen patients were enrolled in the phase 1 b study and the RP2 D for chidamide was determined to be 20 mg,twice a week.A total of 113 patients were treated at the RP2 D in the phase 2 study,and the overall response rate was 60.2%,with a complete response rate of 40.7%.At a median follow-up of 36 months,the median PFS was 10.7 months,with 1-,2-,and 3-year PFS rates of 49.9%,38.0%,and 32.8%,respectively.The Chi-CHOEP regimen was well-tolerated,with grade 3/4 neutropenia occurring in approximately two-thirds of the patients.No unexpected adverse events(AEs)were reported and the observed AEs were manageable.Conclusions:This large cohort phase 1 b/2 study showed that Chi-CHOEP was well-tolerated with modest efficacy in previously untreated PTCL patients. | Wei Zhang Liping Su Lihong Liu Yuhuan Gao Quanshun Wang Hang Su Yuhuan Song Huilai Zhang Jing Shen Hongmei Jing Shuye Wang Xinan Cen Hui Liu Aichun Liu Zengjun Li Jianmin Luo Jianxia He Jingwen Wang O.A.O’Connor Daobin Zhou | 2021 | Cancer Biology & Medicine2021，18，3： | 4 |
| 3 | 3D-人造皮肤模型在化妆品安全性、功效性评价中的应用显示文摘人类皮肤覆盖于整个体表,被称为生命之裳,不仅因为皮肤保护我们的肌肉和内脏免受环境中有害物质的侵害,还源于它的重要审美价值。人类追寻美丽的步伐从未停止过,《齐民要术》里就有各种关于如何配制护肤品的记载。进入21世纪,随着我国人民生活水平的不断提高,化妆品已经成为人们的生活必需品。如何保障化妆品的安全性和功效性,是政府监管部门、化妆品公司和消费者共同关注的问题。 | 张春晓 杜镇建 Zhi Wang Quanshun Zhang 张兴民 | 2014 | 中国化妆品2014，0，6： | 4 |
| 4 | Outcomes of peripheral blood stem cell transplantation in patients from human leukocyte antigen matched or mismatched unrelated donors显示文摘 | Cao Tingting Li Yanfen Wang Quanshun Li Honghua Bo Jian Zhao Yu Jing Yu Wang Shuhong Zhu Haiyan Dou Liping Jia Bojun Gao Chunji Yu Li Huang Wenrong | 2014 | Chinese Medical Journal2014，，14： | 2 |
| 5 | Simulation of stationary Gaussian stochastic wind velocity field 显示文摘 | Ding Quanshun Zhu Ledong Xiang Haifan | 2006 | Wind and Structures2006，9，3： | 1 |
| 6 | Immobilization of urease in metal–organic frameworks via biomimetic mineralization and its application in urea degradation显示文摘Enzyme immobilization has been accepted as an efficient technique for improving the stability and recyclability of enzymes.Herein,biomimetic mineralization strategy was employed to achieve the immobilization of urease in a type of metal–organic frameworks(zeolite imidazolate framework-8,ZIF-8),and the immobilized enzyme urease@ZIF-8 was systematically evaluated for its structure,activity,stability and recyclability,using the hydrolysis of urea as a model.The entrapment of urease was found to be realized in a synchronous manner with the formation of ZIF-8 crystal.The loading of urease in ZIF-8 was measured to be ca.10.6%through the bicinchoninic acid(BCA)protein assay.The encapsulated urease could efficiently maintain its native conformation,which endowed the immobilized urease with excellent activity and stability,even in harsh conditions(e.g.,in the presence of trypsin,acidic or alkali conditions,or at high temperature).Further,urease@ZIF-8 exhibited good recyclability during the degradation of urea,in which it could keep 58.86%of initial activity after being used for 5 cycles.Thus,biomimetic mineralization could be potentially utilized as a promising method to prepare immobilized ureases with superior activity,stability and recyclability,thereby facilitating the construction of efficient catalysts for industrial biocatalysis and biosensing. | Xiao Liang Qing Li Zhiyuan Shi Shaowei Bai Quanshun Li | 2020 | Chinese Journal of Chemical Engineering2020，28，8： | 1 |
| 7 | Simulation of stationary Gaussian stochastic wind velocity field 显示文摘 | Ding Quanshun Zhu Ledong Xiang Haifan | 2006 | Wind and Structures2006，9，3： | 1 |
| 8 | Simulation of stationary Gaussian stochastic wind velocity field 显示文摘 | Ding Quanshun Zhu Ledong Xiang Haifan | 2006 | Wind and Structures2006，9，3： | 1 |
| 9 | Computer simulation of buffeting actions of suspension bridges under turbulent wind 显示文摘 | Ding Quanshun | 2000 | Computers and Structures2000，76，6： | 1 |
| 10 | -Computer simulation of buffeting ac- tions of suspension bridges under turbulent wind 显示文摘 | D1NG Quanshun | 2000 | Computers and Structures2000，76，6： | 1 |
| 11 | An efficient ergodic simulation of multivariate stochastic process with spectral representation 显示文摘 | Ding Quanshun Zhu Ledong Xiang Haifan | 2011 | Probabilistic Engineering Mechanics2011，26，2： | 1 |
| 12 | Coupled flutter analysis of long-span bridges by multimode and full-order approaches显示文摘 | Quanshun Ding Airong Chen Haifan Xiang | 2002 | Journal of Wind Engineering & Industrial Aerodynamics2002，，12： | 1 |
| 13 | Ring-opening polymerization of e-caprolactone catalyzed by a novel thermophilic lipase from fervidobacterium nodosam显示文摘 | Quanshun Li Guangquan Li Shanshan Yua | 2011 | Process Biochemistry2011，46，： | 1 |
| 14 | Ring-opening polymerization of 8-caprolactone catalyzed by a novel thermophilic lipase from fervidobacterium nodosum 显示文摘 | Quanshun Li Guangquan Li Shanshan Yua et a| | 2011 | Process Biochemistry2011，46，： | 1 |
| 15 | Solvent effects on the enantioselectivity of the thermophilic lipase QLM in the resolution of ( R , S )-2-octanol and ( R , S )-2-pentanol显示文摘 | Yuanhong Wang Quanshun Li Zuoming Zhang Jiutong Ma Yan Feng | 2008 | Journal of Molecular Catalysis B Enzymatic2008，，2： | 1 |
| 16 | Simulation of stationary Gaussian stochastic wind velocity field 显示文摘 | Ding Quanshun Zhu Ledong Xiang Haifan | 2006 | Wind and Structures2006，9，3： | 1 |
| 17 | Effect of microstructures on the abrasive wear behaviour of spheroidal 显示文摘 | Luo Quanshun Xie Jingpei Song Yanpei | 1995 | Wear1995，184，： | 1 |
| 18 | Microstructural Characteristics and Mechanical Properties of Low-Alloy, Medium-Carbon Steels After Multiple Tempering显示文摘The microstructure and mechanical properties of NiCrMoV-and NiCrSi-alloyed medium-carbon steels were investigated after multiple tempering. After austenitising, the steels were hardened by oil quenching and subsequently double or triple tempered at temperatures from 250 to 500 °C. The samples were characterised using scanning electron microscopy and X-ray diffraction, while the mechanical properties were evaluated by Vickers hardness testing, V-notched Charpy impact testing and tensile testing. The results showed that the retained austenite was stable up to 400 °C and the applied multiple tempering below this temperature did not lead to a complete decomposition of retained austenite in both steels. It was also found that the microstructure, hardness and impact toughness varied mainly as a function of tempering temperature,regardless of the number of tempering stages. Moreover, the impact toughness of NiCrMoV steel was rather similar after single/triple tempering at different temperatures, while NiCrSi steel exhibited tempered martensite embrittlement after single/double tempering at 400 °C. The observed difference was mainly attributed to the effect of precipitation behaviour due to the effect of alloying additions in the studied steels. | Erfan Abbasi Quanshun Luo Dave Owens | 2019 | Acta Metallurgica Sinica(English Letters)2019，32，1： | 0 |
| 19 | 3D-人造皮肤模型在化妆品安全性、功效性评价中的应用显示文摘人类皮肤覆盖于整个体表,被称为生命之裳,不仅因为皮肤保护我们的肌肉和内脏免受环境中有害物质的侵害,还源于它的重要审美价值。人类追寻美丽的步伐从未停止过,《齐民要术》晕就有各种关于如何配制护肤品的记载。进入21世纪,随着我国人民生活水平不断提高,化妆品已经成为人们的生活必需品。如何保障化妆品的安全性和功效性,是政府监管部门、化妆品公司和消费者共同关注的问题。 | 张春晓 杜镇建 Zhi Wang Quanshun Zhang 张兴民 | 2014 | 北京日化2014，，2： | 0 |
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