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| 1 | Impact of 1.5°C and 2.0°C global warming on aircraft takeoff performance in China显示文摘Associated with global warming, climate extremes such as extreme temperature will significantly increase. Understanding how climate change will impact the airflights is important to the planning of future flight operations. In this study, the impacts of 1.5 and 2 degree's global warming on the aircraft takeoff performance in China are investigated using a unique climate projection data from an international collaboration project named HAPPI. It is found that the mean summer daily maximum temperature, which is a major factor that affects the flight through changing the aircraft's takeoff weight, will increase significantly with magnitude less than 1.5℃ over most parts of China except for the Tibetan Plateau. The half a degree additional global warming will lead to higher extreme temperature in the arid and semi-arid western China, the Tibetan Plateau and the northeastern China, while the change in eastern China is weak. Five airports including Beijing, Shanghai, Kunming, Lasa and Urumqi will see ~1.0°-2.0℃(1.4°-3.0℃) higher daily maximum temperature under 1.5℃(2.0℃) scenario. The half-degree additional warming will lead to a shift toward higher extreme temperature in these five sites. For both1.5° and 2.0℃ scenarios, the number of weight-restriction days will increase significantly at 3 airports including Beijing, Shanghai, and Lasa. Urumqi will witness an increase of weight-restriction days only in 2.0℃ future. | Tianjun Zhou Liwen Ren Haiwen Liu Jingwen Lu | 2018 | Science Bulletin2018，63，11： | 16 |
| 2 | Sinomenine ester derivative inhibits glioblastoma by inducing mitochondria-dependent apoptosis and autophagy by PI3K/AKT/mTOR and AMPK/mTOR pathway显示文摘Glioblastoma multiforme(GBM)in the central nervous system is the most lethal advanced glioma and currently there is no effective treatment for it.Studies of sinomenine,an alkaloid from the Chinese medicinal plant,Sinomenium acutum,showed that it had inhibitory effects on several kinds of cancer.Here,we synthesized a sinomenine derivative,sino-wcj-33(SW33),tested it for antitumor activity on GBM and explored the underlying mechanism.SW33 significantly inhibited proliferation and colony formation of GBM and reduced migration and invasion of U87 and U251 cells.It also arrested the cell cycle at G2/M phase and induced mitochondria-dependent apoptosis.Differential gene enrichment analysis and pathway validation showed that SW33 exerted anti-GBM effects by regulating PI3 K/AKT and AMPK signaling pathways and significantly suppressed tumorigenicity with no obvious adverse effects on the body.SW33 also induced autophagy through the PI3 K/AKT/mTOR and AMPK/mTOR pathways.Thus,SW33 appears to be a promising drug for treating GBM effectively and safely. | Xiangjin Zheng Wan Li Huanli Xu Jinyi Liu Liwen Ren Yihui Yang Sha Li Jinhua Wang Tengfei Ji Guanhua Du | 2021 | Acta Pharmaceutica Sinica B2021，11，11： | 15 |
| 3 | The pleiotropic ABNORMAL FLOWER AND DWARF1 affects plant height, floral development and grain yield in rice显示文摘Moderate plant height and successful establishment of reproductive organs play pivotal roles in rice grain production. The molecular mechanism that controls the two aspects remains unclear in rice. In the present study,we characterized a rice gene, ABNORMAL FLOWER AND DWARF1(AFD1) that determined plant height, floral development and grain yield. The afd1 mutant showed variable defects including the dwarfism, long panicle, low seed setting and reduced grain yield. In addition, abnormal floral organs were also observed in the afd1 mutant including slender and thick hulls, and hull-like lodicules.AFD1 encoded a DUF640 domain protein and was expressed in all tested tissues and organs. Subcellular localization showed AFD1-green fluorescent fusion protein(GFP) was localized in the nucleus. Meantime, our results suggested that AFD1 regulated the expression of cell division and expansion related genes. | Deyong Ren Yuchun Rao Liwen Wu Qiankun Xu Zizhuang Li Haiping Yu Yu Zhang Yujia Leng Jiang Hu Li Zhu Zhenyu Gao Guojun Dong Guangheng Zhang Longbiao Guo Dali Zeng Qian Qian | 2016 | Journal of Integrative Plant Biology2016，58，6： | 4 |
| 4 | Hydrothermal exfoliated molybdenum disulfide nanosheets as anode material for lithium ion batteries显示文摘Ultrathin MoS2nanosheets were prepared in high yield using a facile and effective hydrothermal intercalation and exfoliation route. The products were characterized in detail using X-ray diffraction, scanning electron microscopy, transmission electron microscopy and Raman spectroscopy. The results show that the high yield of MoS2nanosheets with good quality was successfully achieved and the dimensions of the immense nanosheets reached 1 μm–2 μm. As anode material for Li-ion batteries, the as-prepared MoS2nanosheets electrodes exhibited a good initial capacity of 1190 mAh g-1and excellent cyclic stability at constant current density of 50 mA g-1. After 50 cycles, it still delivered reversibly sustained high capacities of 750 mAh g-1. | Yundan Liu Long Ren Xiang Qi Liwen Yang Jun Li Yao Wang Jianxin Zhong | 2014 | Journal of Energy Chemistry2014，23，2： | 4 |
| 5 | Tumorigenic bacteria in colorectal cancer:mechanisms and treatments显示文摘Colorectal cancer(CRC)is the third most common and the second most fatal cancer.In recent years,more attention has been directed toward the role of gut microbiota in the initiation and development of CRC.Some bacterial species,such as Fusobacterium nucleatum,Escherichia coli,Bacteroides fragilis,Enterococcus faecalis,and Salmonella sp.have been associated with CRC,based upon sequencing studies in CRC patients and functional studies in cell culture and animal models.These bacteria can cause host DNA damage by genotoxic substances,including colibactin secreted by pks+Escherichia coli,B.fragilis toxin(BFT)produced by Bacteroides fragilis,and typhoid toxin(TT)from Salmonella.These bacteria can also indirectly promote CRC by influencing host-signaling pathways,such as E-cadherin/β-catenin,TLR4/MYD88/NF-κB,and SMO/RAS/p38 MAPK.Moreover,some of these bacteria can contribute to CRC progression by helping tumor cells to evade the immune response by suppressing immune cell function,creating a proinflammatory environment,or influencing the autophagy process.Treatments with the classical antibacterial drugs,metronidazole or erythromycin,the antibacterial active ingredients,M13@Ag(electrostatically assembled from inorganic silver nanoparticles and the protein capsid of bacteriophage M13),berberine,and zerumbone,were found to inhibit tumorigenic bacteria to different degrees.In this review,we described progress in elucidating the tumorigenic mechanisms of several CRC-associated bacteria,as well as progress in developing effective antibacterial therapies.Specific bacteria have been shown to be active in the oncogenesis and progression of CRC,and some antibacterial compounds have shown therapeutic potential in bacteria-induced CRC.These bacteria may be useful as biomarkers or therapeutic targets for CRC. | Sha Li Jinyi Liu Xiangjin Zheng Liwen Ren Yihui Yang Wan Li Weiqi Fu Jinhua Wang Guanhua Du | 2022 | Cancer Biology & Medicine2022，19，2： | 3 |
| 6 | MELK is an oncogenic kinase essential for metastasis,mitotic progression,and programmed death in lung carcinoma显示文摘Lung cancer is the fastest growth rate of morbidity and mortality in nearly a decade,and remains difficult to treat.Furthermore,the molecular mechanisms underlying its development are still unclear.In this study,bioinformatics analysis showed that MELK was highly expressed in lung cancer and negatively correlated to the survival of lung adenocarcinoma(LUAD).Immunohistochemistry analysis of LUAD patient tissues revealed there were a high level of MELK expression in LUAD.Knockdown of MELK expression inhibits the migration and invasion of LUAD cells,which may be mediated by Twist1,Slug,MMP7,and N-catenin.Overexpression of MELK promoted the growth of LUAD cells in medium,3D Matrigel,and nude mice.Inhibition of MELK by OTSSP167 arrested cycle of LUAD cells at G2/M phase via PLK1-CDC25C-CDK1 pathway,and triggered apoptosis-mediated pyroptosis.Together,these data indicate that MELK is critical for metastasis,mitotic progression,and programmed death of LUAD and may be a promising therapeutic target for LUAD. | Qin Tang Wan Li Xiangjin Zheng Liwen Ren Jinyi Liu Sha Li Jinhua Wang Guanhua Du | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 3 |
| 7 | Interaction Between Variations in Dopamine D2 and Serotonin 2A Receptor is Associated with Short-Term Response to Antipsychotics in Schizophrenia显示文摘Dear Editor,Schizophrenia is a chronic and debilitating brain disorder,which has a strong genetic component with heritability ranging from 66%to 85%[1,2].Currently,antipsychotic drugs remain the most effective treatment for the psychotic symptoms of schizophrenia[3].Because of the severe sideeffects of first-generation antipsychotics(FGAs),secondgeneration antipsychotics(SGAs)have become more widely used in the treatment of schizophrenia. | Liansheng Zhao Huijuan Wang Yamin Zhang Jinxue Wei Peiyan Ni Hongyan Ren Gang Li Qiang Wang Gavin P Reynolds Weihua Yue Wei Deng Hao Yan Liwen Tan Qi Chen Guigang Yang Tianlan Lu Lifang Wang Fuquan Zhang Jianli Yang Keqing Li Luxian Lv Qingrong Tan Yinfei Li Hua Yu Hongyan Zhang Xin Ma Fude Yang Lingjiang Li Chuanyue Wang Huiyao Wang Xiaojing Li Wanjun Guo Xun Hu Yang Tian Xiaohong Ma Jeremy Coid Dai Zhang Chao Chen Tao Li Chinese Antipsychotics Pharmacogenomics Consortium | 2019 | Neuroscience Bulletin2019，35，6： | 3 |
| 8 | Testing the role of genetic variation of the MC4R gene in Chinese population in antipsychotic-induced metabolic disturbance显示文摘Antipsychotic-induced metabolic disturbance(AIMD) is a common adverse effect of antipsychotics with genetics partly underpinning variation in susceptibility among schizophrenia patients. Melanocortin4 receptor(MC4 R) gene, one of the candidate genes for AIMD, has been under-studied in the Chinese patients. We conducted a pharmacogenetic study in a large cohort of Chinese patients with schizophrenia. In this study, we investigated the genetic variation of MC4 R in Chinese population by genotyping two SNPs(rs489693 and rs17782313) in 1,991 Chinese patients and examined association of these variants with the metabolic effects that were often observed to be related to AIMD. Metabolic measures, including body mass index(BMI), waist circumference(WC), glucose, triglyceride, high-density lipoprotein(HDL), and low-density lipoprotein(LDL) levels were assessed at baseline and after 6-week antipsychotic treatment. We found that interaction of SNP×medication status(drug-na?ve/medicated) was significantly associated with BMI, WC, and HDL change %, respectively. Both SNPs were significantly associated with baseline BMI and WC in the medicated group. Moderate association of rs489693 with WC, Triglyceride, and HDL change % were observed in the whole sample. In the drug-na?ve group, we found recessive effects of rs489693 on BMI gain more than 7%, WC and Triglyceride change %, with AA incurring more metabolic adverse effects. In conclusion, the association between rs489693 and the metabolic measures is ubiquitous but moderate. Rs17782313 is less involved in AIMD. Two SNPs confer risk of AIMD to patients treated with different antipsychotics in a similar way. | Yamin Zhang Hongyan Ren Qiang Wang Wei Deng Weihua Yue Hao Yan Liwen Tan Qi Chen Guigang Yang Tianlan Lu Lifang Wang Fuquan Zhang Jianli Yang Keqing Li Luxian Lv Qingrong Tan Hongyan Zhang Xin Ma Fude Yang Lingjiang Li Chuanyue Wang Dai Zhang Liansheng Zhao Huiyao Wang Xiaojing Li Wanjun Guo Xun Hu Yang Tian Xiaohong Ma Tao Li Chinese Antipsychotics Pharmacogenomics Consortium | 2019 | Science China(Life Sciences)2019，62，4： | 3 |
| 9 | Anthropogenic influence on extreme Meiyu rainfall in 2020 and its future risk显示文摘Eastern China experienced excessive Meiyu rainfall in the summer of 2020,with a long rainy season and frequent extreme rainfall events.Extreme rainfall occurred on daily to monthly time scales.In particular,persistent heavy rainfall events occurred;e.g.,the maximum accumulated rainfall over four consecutive weeks(Rx28day)in the lower reaches of the Yangtze River was 94%greater than climatology,breaking the observational record since 1961.With ongoing anthropogenic climate change,it is vital to understand the anthropogenic influence on this extreme rainfall event and its driving mechanisms.In this study,based on multi-model simulations under different external forcings that participate in the Detection and Attribution Model Intercomparison Project(DAMIP)in the Coupled Model Intercomparison Project-phase 6(CMIP6),we show that anthropogenic forcing has reduced the probability of the Rx28day extreme rainfall as that in observations in the lower reaches of the Yangtze River in 2020,by 46%(22–62%).Specifically,greenhouse gas(GHG)emissions have increased the probability by 44%as a result of atmospheric warming and moistening.However,this effect was offset by anthropogenic aerosols,which reduced the probability by 73%by reducing atmospheric moisture and weakening the East Asian summer monsoon circulation.With the continuous emissions of GHGs and reductions in aerosols in the future,similar persistent heavy rainfall events are projected to occur more frequently.A higher occurrence probability is expected under higher emission scenarios,which is estimated to be 4.6,13.6 and 27.7 times that in the present day under the SSP1-2.6,SSP2-4.5,and SSP5-8.5 emission scenarios,respectively,by the end of the 21st century.Thus,efficient mitigation measures will help to reduce the impacts related to extreme rainfall. | Tianjun ZHOU Liwen REN Wenxia ZHANG | 2021 | Science China Earth Sciences2021，64，10： | 2 |
| 10 | Sphingosine kinase 1 promotes growth of glioblastoma by increasing inflammation mediated by the NF-κB/IL-6/STAT3 and JNK/PTX3 pathways显示文摘Glioblastoma(GBM)is the most challenging malignant tumor of the central nervous system because of its high morbidity,mortality,and recurrence rate.Currently,mechanisms of GBM are still unclear and there is no effective drug for GBM in the clinic.Therefore,it is urgent to identify new drug targets and corresponding drugs for GBM.In this study,in silico analyses and experimental data show that sphingosine kinase 1(SPHK1)is up-regulated in GBM patients,and is strongly correlated with poor prognosis and reduced overall survival.Overexpression of SPHK1 promoted the proliferation,invasion,metastasis,and clonogenicity of GBM cells,while silencing SPHK1 had the opposite effect.SPHK1 promoted inflammation through the NF-κB/IL-6/STAT3 signaling pathway and led to the phosphorylation of JNK,activating the JNK-JUN and JNK-ATF3 pathways and promoting inflammation and proliferation of GBM cells by transcriptional activation of PTX3.SPHK1 interacted with PTX3 and formed a positive feedback loop to reciprocally increase expression,promote inflammation and GBM growth.Inhibition of SPHK1 by the inhibitor,PF543,also decreased tumorigenesis in the U87-MG and U251-MG SPHK1 orthotopic mouse models.In summary,we have characterized the role and molecular mechanisms by which SPHK1 promotes GBM,which may provide opportunities for SPHK1-targeted therapy. | Wan Li Hongqing Cai Liwen Ren Yihui Yang Hong Yang Jinyi Liu Sha Li Yizhi Zhang Xiangjin Zheng Wei Tan Guanhua Du Jinhua Wang | 2022 | Acta Pharmaceutica Sinica B2022，12，12： | 2 |
| 11 | Progress on diagnostic and prognostic markers of pancreatic cancer显示文摘Pancreatic cancer is a malignant disease characterized by low survival and high recurrence rate,whose patients are mostly at the stage of locally advanced or metastatic disease when first diagnosed.Early diagnosis is particularly important because prognostic/predictive markers help guide optimal individualized treatment regimens.So far,CA19-9 is the only biomarker for pancreatic cancer approved by the FDA,but its effectiveness is limited by low sensitivity and specificity.With recent advances in genomics,proteomics,metabolomics,and other analytical and sequencing technologies,the rapid acquisition and screening of biomarkers is now possible.Liquid biopsy also occupies a significant place due to its unique advantages.In this review,we systematically describe and evaluate the available biomarkers that have the greatest potential as vital tools in diagnosing and treating pancreatic cancer. | HONG YANG WAN LI LIWEN REN YIHUI YANG YIZHI ZHANG BINBIN GE SHA LI XIANGJIN ZHENG JINYI LIU SEN ZHANG GUANHUA DU BO TANG HONGQUAN WANG JINHUA WANG | 2023 | Oncology Research2023，31，2： | 1 |
| 12 | Solvothermal synthesis, cubic structure and multicolor upconversion emis- sion of ultrasmall monodisperse lanthanide-doped BaYF4 nanocrystals 显示文摘 | Ma Mo Yang Liwen Ren Guozhong | 2011 | J Imminescence2011，131，： | 1 |
| 13 | Recent Development and Preliminary Results of Chinese Meridian Project显示文摘The Meridian Project is a ground-based network program to monitor solar-terrestrial space environment,which consists of a chain of 15 ground-based observatories located roughly along 120°E longitude and 30°N latitude.The Meridian project started in 2008,and its construction was completed by 2011.The integration and test phase of the Meridian Project conducted in 2011 demonstrated its observation capabilities as expected.The project will be in full operation in 2012. This report gives an overview of the recent development and preliminary results of the Meridian Project since 2010. | WANG Chi REN Liwen | 2013 | 空间科学学报2013，33，1： | 1 |
| 14 | International Meridian Circle Program显示文摘The Earth is buffered from the ferocious onslaught of the solar wind by a thin layer of matter known as the atmosphere and geospace.This layer absorbs energy from irradiance and outburst from the Sun,as well as from disasters,transient phenomena and anthropogenic emissions originated from Earth.Through complicated physics,the absorbed energy changes the atmospheric and geospace state and sometimes gets re-released to power extreme events such as space weather.Taking place globally,these complicated processes cannot be understood unless they are studied globally.The Chinese scientists have proposed the International Meridian Circle Program(IMCP)to meet this demand.By operating nearly 1000 instruments encompassing all latitudes along with the 120°E–60°W longitudes,IMCP aims,for the first time,to construct comprehensive 3D data representation of the atmosphere and geospace on a global scale and empower interdisciplinary research to tackle key questions related to Earth’s environment and climate change. | LIU William WANG Chi SHEN Xuhui WU Jian BLANC Michel YAN Yihua FU Suiyan YUE Xinan LEI Jiuhou GONG Wei ZHANG Shaodong ZHANG Qinghe WANG Xin YANG Jing ZHANG Xiaoxin GAO Jing XU Jiyao YANG Guotao LI Hui REN Liwen YANG Fang | 2020 | 空间科学学报2020，40，5： | 1 |
| 15 | Ultralow Interfacial Thermal Resistance of Graphene Thermal Interface Materials with Surface Metal Liquefaction显示文摘Developing advanced thermal interface materials(TIMs)to bridge heat-generating chip and heat sink for constructing an efficient heat transfer interface is the key technology to solve the thermal management issue of high-power semiconductor devices.Based on the ultra-high basal-plane thermal conductivity,graphene is an ideal candidate for preparing high-performance TIMs,preferably to form a vertically aligned structure so that the basal-plane of graphene is consistent with the heat transfer direction of TIM.However,the actual interfacial heat transfer efficiency of currently reported vertically aligned graphene TIMs is far from satisfactory.In addition to the fact that the thermal conductivity of the vertically aligned TIMs can be further improved,another critical factor is the limited actual contact area leading to relatively high contact thermal resistance(20-30 K mm^(2) W^(−1))of the“solid-solid”mating interface formed by the vertical graphene and the rough chip/heat sink.To solve this common problem faced by vertically aligned graphene,in this work,we combined mechanical orientation and surface modification strategy to construct a three-tiered TIM composed of mainly vertically aligned graphene in the middle and micrometer-thick liquid metal as a cap layer on upper and lower surfaces.Based on rational graphene orientation regulation in the middle tier,the resultant graphene-based TIM exhibited an ultra-high thermal conductivity of 176 W m^(−1) K^(−1).Additionally,we demonstrated that the liquid metal cap layer in contact with the chip/heat sink forms a“liquid-solid”mating interface,significantly increasing the effective heat transfer area and giving a low contact thermal con-ductivity of 4-6 K mm^(2) W^(−1) under packaging conditions.This finding provides valuable guidance for the design of high-performance TIMs based on two-dimensional materials and improves the possibility of their practical application in electronic thermal management. | Wen Dai Xing-Jie Ren Qingwei Yan Shengding Wang Mingyang Yang Le Lv Junfeng Ying Lu Chen Peidi Tao Liwen Sun Chen Xue Jinhong Yu Chengyi Song Kazuhito Nishimura Nan Jiang Cheng-Te Lin | 2023 | Nano-Micro Letters2023，15，1： | 0 |
| 16 | Understanding Differences in Event Attribution Results Arising from Modeling Strategy显示文摘While there is high confidence that human activities have increased the likelihood and severity of hot extreme events over many parts of the world,there is notable spread in quantitative estimates of anthropogenic influence even on a single event.To better understand the uncertainty of attribution results,here we compare different event attribution methods using the 2015 July-August record-breaking heat event in northwestern China as a case study.To address the anthropogenic influence on the likelihood of the extreme event,we employ attribution runs with two modeling strategies—atmosphere-only and coupled simulations—with different conditioning.In atmosphere-only attribution runs,given the observed sea surface boundary conditions and external forcings in 2015,it is estimated that anthropogenic forcing has increased the likelihood of hot extremes such as that observed in 2015 in the target region,by approximately 27 and 12 times in MIROC5 and HadGEM3-A-N216,respectively.In Coupled Model Intercomparison Project phase 5(CMIP5)fully coupled attribution runs,given the external forcing at the 1961-2015 level and regardless of sea surface boundary conditions,there is a 21-fold increase in the likelihood of similar heat events due to anthropogenic forcing.The differences in quantitative attribution results can arise from modeling strategies,which are tightly linked to different conditioning in attribution.Specifically,different ocean boundary conditions,external forcings,and air-sea coupling processes contribute to different attribution results between the two modeling strategies.Within each modeling strategy,model uncertainty affects quantitative attribution conclusions.The comparison of different attribution methods provides a better understanding of the uncertainty of attribution results,which is useful in synthesizing and interpreting attribution results. | Wenxia ZHANG Liwen REN Tianjun ZHOU | 2022 | Journal of Meteorological Research2022，36，1： | 0 |
| 17 | Dust Acoustic Wave in Dusty Plasmas With Streaming Ions Under Ultraviolet Irradiation显示文摘The reductive perturbation method is applied to investigate the dust acoustic soliton in dusty plasmas with streaming ions under ultraviolet irradiation theoretically and numerically.The self-consistent dust charge variation is taken into account.It is shown that the ultraviolet irradiation can significantly lower the magnitude of the dust negative charge,and ion streaming velocity firstly raise the magnitude of the dust negative charge and then lower it.With the growth of(Ultraviolet) UV photo flux or ion streaming velocity,the phase velocity and width of the solitary waves decrease, whereas its amplitude increases. | REN Liwen WANG Chi | 2012 | 空间科学学报2012，32，2： | 0 |
| 18 | MELK is an oncogenic kinase essential for metastasis,mitotic progression,and programmed death in lung carcinoma显示文摘Lung cancer is the fastest growth rate of morbidity and mortality in nearly a decade,and remains difficult to treat.Furthermore,the molecular mechanisms underlying its development are still unclear.In this study,bioinformatics analysis showed that MELK was highly expressed in lung cancer and negatively correlated to the survival of lung adenocarcinoma(LUAD).Immunohistochemistry analysis of LUAD patient tissues revealed there were a high level of MELK expression in LUAD.Knockdown of MELK expression inhibits the migration and invasion of LUAD cells,which may be mediated by Twist1,Slug,MMP7,and N-catenin.Overexpression of MELK promoted the growth of LUAD cells in medium,3D Matrigel,and nude mice.Inhibition of MELK by OTSSP167 arrested cycle of LUAD cells at G2/M phase via PLK1-CDC25C-CDK1 pathway,and triggered apoptosis-mediated pyroptosis.Together,these data indicate that MELK is critical for metastasis,mitotic progression,and programmed death of LUAD and may be a promising therapeutic target for LUAD. | Qin Tang Wan Li Xiangjin Zheng Liwen Ren Jinyi Liu Sha Li Jinhua Wang Guanhua Du | 2021 | Signal Transduction and Targeted Therapy2021，6，1： | 0 |
| 19 | Examining residual spatial correlation in variation partitioning of beta diversity in a subtropical forest显示文摘Aims The relative roles of ecological processes in structuring beta diver-sity are usually quantified by variation partitioning of beta diversity with respect to environmental and spatial variables or gamma di-versity.However,if important environmental or spatial factors are omitted,or a scale mismatch occurs in the analysis,unaccounted spatial correlation will appear in the residual errors and lead to re-sidual spatial correlation and problematic inferences.Methods Multi-scale ordination(MSO)partitions the canonical ordination results by distance into a set of empirical variograms which charac-terize the spatial structures of explanatory,conditional and residual variance against distance.Then these variance components can be used to diagnose residual spatial correlation by checking assump-tions related to geostatistics or regression analysis.In this paper,we first illustrate the performance of MSO using a simulated data set with known properties,thus making statistical issues explicit.We then test for significant residual spatial correlation in beta diversity analyses of the Gutianshan(GTS)24-ha subtropical forest plot in eastern China.Important Findings Even though we used up to 24 topographic and edaphic variables mapped at high resolution and spatial variables representing spa-tial structures at all scales,we still found significant residual spatial correlation at the 10 m×10 m quadrat scale.This invalidated the analysis and inferences at this scale.We also show that MSO pro-vides a complementary tool to test for significant residual spatial correlation in beta diversity analyses.Our results provided a strong argument supporting the need to test for significant residual spatial correlation before interpreting the results of beta diversity analyses. | Ke Cao Xiangcheng Mi Liwen Zhang Haibao Ren Mingjian Yu Jianhua Chen Jintun Zhang Keping Ma | 2019 | Journal of Plant Ecology2019，12，4： | 0 |
| 20 | Progress of International Meridian Circle Program显示文摘Based on the Chinese Meridian Project(CMP),the International Meridian Circle Program(IMCP)aims to coordinate the deployment of a comprehensive ground-based monitoring network along the 120°E-60°W Great Meridian Circle to track the propagation and evolution of space weather events from the Sun to the Earth,as well as the imprints of other major natural and anthropic hazards on the ionosphere,the middle and upper atmosphere.Currently,we have completed the IMCP headquarters building in Beijing and established the China-Brazil Joint Laboratory for Space Weather in cooperation with Brazil.Meanwhile,the Chinese Meridian Project PhaseⅡand different components of the IMCP observation system are under construction. | LIU William MICHEL Blanc WANG Chi XU Jiyao LI Hui REN Liwen LIU Zhengkuan ZHU Yajun LI Guozhu LI Lei ZEREN Zhima YANG Fang | 2022 | 空间科学学报2022，42，4： | 0 |
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