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| 1 | The BUD2 mutation affects plant architecture through altering cytokinin and auxin responses in Arabidopsis显示文摘植物生长素和细胞激动素的比率在由支持或镇压调整天线建筑学起一个关键作用腋的芽长出。我们以前鉴别了显示的 Arabidopsis 变异的 bud2 改变了根和射击建筑学,它源于 S-adenosylmethionine decarboxylase 的 loss-of-function 4 (SAMDC4 ) 。在这研究,我们证明 BUD2 能被植物生长素导致,并且正式就职依赖于植物生长素发信号。BUD2 的变化导致弱敏到植物生长素和超敏性到细胞激动素,它被胼胝正式就职试金证实。我们的学习建议 polyamines 可以在通过影响细胞激动素和敏感的动态平衡到植物生长素和细胞激动素调整植物建筑学起他们的作用。 | Xia Cui Chunmin Ge Renxiao Wang Huanzhong Wang Weiqi Chen Zhiming Fu Xiangning Jiang Jiayang Li Yonghong Wang | 2010 | Cell Research2010，20，5： | 12 |
| 2 | Quantitative study of protein coronas on gold nano- particles with different surface modifications显示文摘 | Menghua Cui Renxiao Liu Zhaoyi Deng Guanglu Ge Ying Liu Liming Xie | 2014 | Nano Research2014，7，3： | 6 |
| 3 | Kirigami-inspired,highly stretchable microsupercapacitor patches fabricated by laser conversion and cutting显示文摘The recent developments in material sciences and rational structural designs have advanced the field of compliant and deformable electronics systems.However,many of these systems are limited in either overall stretchability or areal coverage of functional components.Here,we design a construct inspired by Kirigami for highly deformable microsupercapacitor patches with high areal coverages of electrode and electrolyte materials.These patches can be fabricated in simple and efficient steps by laser-assisted graphitic conversion and cutting.Because the Kirigami cuts significantly increase structural compliance,segments in the patches can buckle,rotate,bend and twist to accommodate large overall deformations with only a small strain(<3%)in active electrode areas.Electrochemical testing results have proved that electrical and electrochemical performances are preserved under large deformation,with less than 2%change in capacitance when the patch is elongated to 382.5%of its initial length.The high design flexibility can enable various types of electrical connections among an array of supercapacitors residing in one patch,by using different Kirigami designs. | Renxiao Xu Anton Zverev Aaron Hung Caiwei Shen Lauren Irie Geoffrey Ding Michael Whitmeyer Liangjie Ren Brandon Griffin Jack Melcher Lily Zheng Xining Zang Mohan Sanghadasa Liwei Lin | 2018 | Microsystems & Nanoengineering2018，4，1： | 6 |
| 4 | Quantitative Analysis of Cytokinins in Plants by High Performance Liquid Chromatography:Electronspray Ionization Ion Trap Mass Spectrometry显示文摘The present paper introduces a highly sensitive and selective method for simultaneous quantification of 12 cytokinins(free form and their conjugates).The method includes a protocol of extraction with methanol/water/formic acid(15/4/1,v/v/v) to the micro-scale samples,pre-purification with solid phase extraction(SPE) cartridges of the extracts,separation with a high performance liquid chromatography(HPLC) and detection by an electrospray ionization ion trap mass spectrometry(ESI-Ion trap-MS) system in a consecutive ion monitoring(CRM) mode at the three stage fragmentation of mass spectrometry(MS 3).The lowest detection level of the cytokinins of the method reaches 0.1-2.0 pg with a very wide range of linear regression from 1-512 pg,at the coefficient factors of 0.98-0.99.The feasibility of this method has been proven in the application of the method to the analysis of the trace-amount contents of cytokinins in the micro-scale samples of various types of plant materials,such as aerial parts of rice and poplar leaves etc.12 endogenous cytokinins had been identified and quantified in the plant tissues,with an acceptable relatively higher recovery rate from 40% to 70%. | Weiqi Chen Ying Gai Shichang Liu Renxiao Wang Xiangning Jiang | 2010 | Journal of Integrative Plant Biology2010，52，10： | 4 |
| 5 | An unusual UMP C-5 methylase in nucleoside antibiotic polyoxin biosynthesis显示文摘 | Wenqing Chen Yan Li Jie Li Lian Wu Renxiao Wang Zixin Deng Jiahai Zhou | 2016 | Protein & Cell2016，7，9： | 2 |
| 6 | Deep learning for non-parameterized MEMS structural design显示文摘The geometric designs of MEMS devices can profoundly impact their physical properties and eventual performances.However,it is challenging for researchers to rationally consider a large number of possible designs,as it would be very time-and resource-consuming to study all these cases using numerical simulation.In this paper,we report the use of deep learning techniques to accelerate the MEMS design cycle by quickly and accurately predicting the physical properties of numerous design candidates with vastly different geometric features.Design candidates are represented in a nonparameterized,topologically unconstrained form using pixelated black-and-white images.After sufficient training,a deep neural network can quickly calculate the physical properties of interest with good accuracy without using conventional numerical tools such as finite element analysis.As an example,we apply our deep learning approach in the prediction of the modal frequency and quality factor of disk-shaped microscale resonators.With reasonable training,our deep learning neural network becomes a high-speed,high-accuracy calculator:it can identify the flexural mode frequency and the quality factor 4.6×10^(3)times and 2.6×10^(4)times faster,respectively,than conventional numerical simulation packages,with good accuracies of 98.8±1.6%and 96.8±3.1%,respectively.When simultaneously predicting the frequency and the quality factor,up to~96.0%of the total computation time can be saved during the design process.The proposed technique can rapidly screen over thousands of design candidates and promotes experience-free and data-driven MEMS structural designs. | Ruiqi Guo Fanping Sui Wei Yue Zekai Wang Sedat Pala Kunying Li Renxiao Xu Liwei Lin | 2022 | Microsystems & Nanoengineering2022，8，4： | 2 |
| 7 | NMR Studies on the Interaction between Oncogene RET G-Quadruplex and Berberine显示文摘of main observation and conclusion RET G-quadruplex DNA(G4-DNA)is formed in the promoter region of RET protein,which is involved in the initiation and progression of human cancers.Berberine inhibits cancer cell growth through interactions with RET G4-DNA,but how it binds to RET G4-DNA remains unknown.Previously,we reported that colchicine selectively bound to RET G4-DNA,but the structural basis of its binding selectivity is still unclear.Here,mainly by NMR,we demonstrated how berberine bound to RET G4-DNA in a means different from colchicine,and implied several key determinants for small molecules specifically binding to one G4-DNA. | Fei Wang Chunxi Wang Yaping Liu Wenxian Lan Renxiao Wang Shaohua Huang Chunyang Cao | 2020 | Chinese Journal of Chemistry2020，38，12： | 2 |
| 8 | LigBuilder:A multipurpose program for structure-based drug design显示文摘 | Wang Renxiao Gao Ying Lai Luhua | 2000 | J Mol Model2000，6，： | 1 |
| 9 | All-Orientation Search and All-Placement Search in Comparative Molecular Field Analysis显示文摘 | Renxiao Wang Ying Gao Liang Liu Luhua Lai | 1998 | Journal of Molecular Modeling1998，，8： | 1 |
| 10 | Synthesis of monodisperse crosslinked polystyrene microspheres显示文摘Monodisperse crosslinked polystyrene(CPS)particles were prepared through the normal emulsion polymerization method by adding crosslinker-divinylbenzene(DVB)into the reaction system after polystyrene(PS)particles grew to^80%of the final size.When the amount of crosslinker DVB added was less than 6.17 wt%based on styrene,the prepared CPS particles were spherical and uniform and the size of the CPS particles could be predicted through the normal emulsion method.The glass transition temperature(Tg)of the prepared CPS particles was higher than that of un-crosslinked PS particles and,the more crosslinker that was added,the higher the Tg of CPS Particles.The prepared CPS particles had strong resistance to organic solvents. | Jiang Kai Chen Sheng-Li Dong Peng Liu Renxiao | 2008 | Petroleum Science2008，5，4： | 1 |
| 11 | SCORE: A New Empirical Method for Estimating the Binding Affinity of a Protein-Ligand Complex 显示文摘 | WANG Renxiao LIU Liang IAI Luhua | 1998 | Journal of Molecular Modeling1998，4，： | 1 |
| 12 | Synthesis of 4-(2-Phenylhydrazono)-l-(4-phenylthiazol-2-yl)- 1H-pyrazol-5(4H)-one Compounds and Characterization of Their Affinities to Anti-apoptotic Bcl-2 Family Proteins显示文摘包含 thiazol-2-yl-1H-pyrazol-5 (4H ) 的有机化合物一一半被知道与万用的药理学应用被联系。在这研究,我们为准备 -1-(4-phenylthiazol-2-yl)-1H-pyrazol-5(4H)-one 加重的 4-(2-phenylhydrazono ) 描述方法。一套 26 混合物与全面收益变化在之间被综合 37%92% 。他们在荧光被测试对三 anti-apoptotic Bcl-2 家庭蛋白质,包括的 Bcl-xL, Bcl-2,和 Mcl-1 的基于极化的有约束力的试金。我们的结果显示混合物的这个班不是这些 anti-apoptotic Bcl-2 家庭蛋白质的有效禁止者。他们的导致 apoptosis 效果被 Gavathiotis 等可能由于是的 BAX 激活建议。在他们的最近的学习。然而,另外的可能性不应该被忽略。另外,我们获得的水晶结构表明 exocyclic 在混合物的班在(Z) | Shicheng Shi Li Han Mi Zhou Yangfeng Li Zhen Li Biao Yu Renxiao Wang | 2013 | Chinese Journal of Chemistry2013，31，9： | 1 |
| 13 | SCORE: A New Empirical Method for Estimating the Binding Affinity of a Protein-Ligand Complex显示文摘 | Renxiao Wang Liang Liu Luhua Lai Youqi Tang | 1998 | Journal of Molecular Modeling1998，，12： | 1 |
| 14 | A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells显示文摘 | Hui Song Renxiao Wang Shaomeng Wang | 2005 | PNAS2005，102，13： | 1 |
| 15 | Simulation study on the centrifugal casting wet-type cylinder liner based on Pro CAST显示文摘 | Su Linglu Fu Renxiao Zhang Shuangjie | 2014 | Applied Thermal Engineering2014，73，： | 1 |
| 16 | SCORE:A New Empirical Method for Estimating the Binding Affinity of a Protein-Ligand Complex显示文摘 | Renxiao Wang Liang Liu Luhua Lai | 1998 | Journal of Molecular Modeling1998，4，： | 1 |
| 17 | Highly flexible,foldable,and rollable microsupercapacitors on an ultrathin polyimide substrate with high power density显示文摘The design and functionality of extremely flexible,foldable,and rollable microsupercapacitors(MSCs)with in-plane interdigital electrodes that consist of single-walled carbon nanotube(SWCNT)networks on an ultrathin polyimide substrate are demonstrated through experiments and finite element simulations.The all-solid-state MSCs can be reversibly bent,folded,and rolled purely elastically without degradation of their electrical performance.The simulation results confirm that the deformation in bent,folded,and rolled MSCs is purely elastic.The high power density(1125W cm^(–3))and small time constant(1 ms)of the present MSCs are comparable to those of aluminum electrolytic capacitors.The MSCs operate at scan rates of up to 1000 V s^(–1),are characterized by a volumetric capacitance of 18 F cm^(–3) and an energy density of 1.6 mWh cm^(–3),and exhibit superior electrochemical stability with 96% capacity retention even after 100,000 charge/discharge cycles.The developed MSCs demonstrate high potential for integration in flexible and wearable electronic systems. | Juan Pu Xiaohong Wang Renxiao Xu Sixing Xu Kyriakos Komvopoulos | 2018 | Microsystems & Nanoengineering2018，4，1： | 1 |
| 18 | Monodisperse SiO2/TiO2 coreshell colloidal spheres:synthesis and ordered selfassembling 显示文摘 | Liu Renxiao Dong Peng Chen Shengli | 2005 | Chemistry Letters2005，34，54： | 1 |
| 19 | High-efficient Isolation of Plant Viral RNA via TMAOH-modified Fe3O4 Magnetic Nanoparticles显示文摘 | TANG Yan ZHAO Xiaoli CHU Linya SUN Ning LIU Renxiao DENG Congliang GE Guanglu | 2014 | Chemical Research in Chinese Universities2014，30，1： | 0 |
| 20 | Drug discovery by targeting the protein–protein interactions involved in autophagy显示文摘Autophagy is a cellular process in which proteins and organelles are engulfed in autophagosomal vesicles and transported to the lysosome/vacuole for degradation.Protein–protein interactions(PPIs)play a crucial role at many stages of autophagy,which present formidable but attainable targets for autophagy regulation.Moreover,selective regulation of PPIs tends to have a lower risk in causing undesired off-target effects in the context of a complicated biological network.Thus,small-molecule regulators,including peptides and peptidomimetics,targeting the critical PPIs involved in autophagy provide a new opportunity for innovative drug discovery.This article provides general background knowledge of the critical PPIs involved in autophagy and reviews a range of successful attempts on discovering regulators targeting those PPIs.Successful strategies and existing limitations in this field are also discussed. | Honggang Xiang Mi Zhou Yan Li Lu Zhou Renxiao Wang | 2023 | Acta Pharmaceutica Sinica B2023，13，11： | 0 |
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