|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Genome of Wild Mandarin and Domestication History of Mandarin显示文摘官员(柠檬 reticulata ) 是世界范围的最重要的柠檬庄稼之一。它的驯服被相信发生在华南,它是四几千年的官员耕作的中心之一。我们在 Nanling 区域附近收集了官员的自然野人口并且在附近栽培了 landraces。我们发现柠檬性的酸水平戏剧性地在栽培官员被减少。理解 ? 官员驯服的基因基础,我们 de novo 装配了野官员的一个草稿染色体并且分析了一套 104 个柠檬染色体。我们发现 Mangshan 官员是一种原始类型并且二个独立驯服事件发生了,分别地导致在北方和南方 Nanling 山的二组栽培官员(MD1 和 MD2 ) 。二个瓶颈和有效人口尺寸的二扩大为栽培官员的 MD1 组被识别。然而,在 MD2 组织 ? 在人口尺寸有长、连续的减少。MD1 和 MD2 官员从栽培 pummelo 种类显示出种间的基因渗入的不同模式。我们在官员的驯服期间在选择下面可能在基因在柠檬酸盐内容的规定包含了的 aconitate hydratase (ACO ) 识别了高分叉的一个区域,它是。这研究为现存野官员人口的地理起源提供具体基因证据并且使驯服和官员的进化历史清楚些。 | Lun Wang Fa He Yue Huang Jiaxian He Shuizhi Yang Jiwu Zeng Chongling Deng Xiaolin Jiang Yiwen Fang Shaohua Wen Rangwei Xu Huiwen Yu Xiaoming Yang Guangyan Zhong Chuanwu Chen Xiang Yan Changfu Zhou Hongyan Zhang Zongzhou Xie Robert M. Larkin Xiuxin Deng Qiang Xu | 2018 | Molecular Plant2018，11，8： | 14 |
| 2 | Effects of culm carbohydrate partitioning on basal stem strength in a high-yielding rice population显示文摘Rice culm carbohydrate transport can simultaneously affect grain filling and stem lodging resistance by regulating non-structural carbohydrate(NSC) and structural carbohydrate(SC) contents. However, the relationship between carbohydrate transposition and culm strength is not well documented. Accordingly, a high-yielding hybrid rice cultivar(Y Liangyou 2) was tested under different N fertilization regimes at two locations, Taoyuan(a special high-yield eco-site), Yunnan province and Danyang(a representative eco-site of the middle and lower Yangtze), Jiangsu province, China. Significantly higher grain yield and basal stem strength were found at Taoyuan than Danyang under all N rates throughout the two-year experiment. At heading stage, soluble sugars, starch, cellulose and lignin contents of the basal culm at Taoyuan were significantly 132.0%, 73.7%, 1.2%, and 62.7% higher than those at Danyang, respectively. At 20 days after heading, soluble sugars and starch content at Taoyuan decreased significantly compared to Danyang, but lignin content remained higher. Culm carbohydrate transport to kernels at Taoyuan was significantly greater than that at Danyang, and the proportion of soluble sugars and starch was correspondingly 62.9%lower. However, the proportion of lignin and cellulose was 22.7% higher at Taoyuan than that at Danyang. Soluble sugars and starch partitioning were significantly reduced under an increased nitrogen application rate, but SC partitioning was little affected. There were significant positive correlations between basal culm bending stress and dry weight and cellulose and lignin proportions at both locations under all N rates, suggesting that the higher SC proportion at 20 days after heading was primarily responsible for culm strength.These results suggest that high-yielding rice populations with greater culm strength require both moderate NSC transport and greater SC accumulation. | Jun Zhang Ganghua Li Qingyu Huang Zhenghui Liu Chengqiang Ding She Tang Lin Chen Shaohua Wang Yanfeng Ding Weijian Zhang | 2017 | The Crop Journal2017，5，6： | 13 |
| 3 | Carbon and Strontium Isotopes of Late Palaeozoic Marine Carbonates in the Upper Yangtze Platform,Southwest China显示文摘238 marine carbonate samples were collected from seven sedimentary sections ofthe entire late Palaeozoic (Permian, Carboniferous and Devonian) in the Upper Yangtze Plat-form, southwest China. Based on the absence of cathodoluminescence and very low Mn (gener-ally<50 ppm) contents of the samples, it is thought that they contain information on the orig-inal sea water geochemistry. The results of isotopic analyses of these samples are presented interms of δ13C and 87Sr/86Sr ratios versus geological time. The strontium data, consistent withother similar data based on samples from North America, Europe, Africa and other areas inAsia, support the notion of a global consistency in strontium isotope composition of marinecarbonates. The strontium data exhibit three intervals of relatively low 87Sr/86Sr ratios in thelate Middle Devonian to early Late Devonian, Early Carboniferous and Early Permian, corre-sponding to global eustatic high sea level stands. The lowest 87Sr/86Sr ratio recorded in theLate Permian was probably caused by substantial basalt eruptions in the Upper Yangtze Plat-form at the time. Three corresponding periods of relatively high δ13C values at roughly the samethe intervals were caused by a relatively high rate of accumulation of organic carbon duringsea level rises at these times. The deposition of coal was probably responsible for the increaseof sea water δ13C at other times. The δ13C values drop dramatically near theDevonian/Carboniferous, Carboniferous/Permian and Permian/Triassic boundaries, con-sistent with other similar data, which further support the notion that geological time boundariesare associated with mass extinction and subsequent rejuvenation. | Huang Sijing and Zhou Shaohua State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation,Chengdu University of Technology, Chengdu, 610059, Sichuan, China Geological Institute, University of Copenhagen, Oster Voldgade 10,DK-1350 Copenhagen K,Denmark | 1997 | Acta Geologica Sinica(English Edition)1997，71，3： | 11 |
| 4 | A^200 ka pollen record from Okinawa Trough:Paleoenvironment reconstruction of glacial-interglacial cycles显示文摘Pollen analysis was carried out on the Core MD982194 of 29.78 m retrieved from the Middle Okinawa Trough which was dated as old as^200 ka BP.The results revealed that pollen assemblages mainly presented an alternation of coniferous and herb pollen.The coniferous saccate pollen,principally Pinus and Tsuga,predominated in most parts of the core,especially highlighted in the interstadial stages including MIS 1,3,5 and MIS7,whereas the herb pollen significantly increased in the glacial periods.Thus the pollen flora and their percentages showed the sensitive changes under the influence of ice volume during the glacial and interglacial periods.Our record from this core has first documented that the percentage of Cyperaceae was extremely high in the glacial stages with a notable increase in Artemisia,Gramineae,Asteraceae,Chenopodiaceae,and freshwater algae,which can be used as a proxy for sea-level change at the study site because of their close negative correlation of the orbital-scale changes in sea level.The distance between the continental coastline and the Okinawa Trough has deeply shortened due to the sea-level drop in the LGM.As a result,the sediment materials from Yangtze River were extensively deposited on the flat,exposed continental shelf owing to the rapid decline of river flow speed,leading to that pollen grains from Okinawa Trough are derived mainly from the flat coastal vegetation of exposed continental shelf at glacial stages.Changes of pollen assemblage were consistent with the variation of temperature and humidity,which showed that the percentage of arboreal pollen was highly augmented at MIS 7,5 and MIS 1,corresponding to the strengthening of the East Asian summer monsoon and increasing of rainfall.Moreover,the peak of Pinus percentage in MIS 5.3,5.1 and MIS 3.3 may be closely linked by orbital and sub-orbital cycles of solar radiation and monsoonal variability.The present study of core MD981294 implied lower temperature and precipitation during the lowest sea-level stage(LGM),and more visibly testified that the vegetation of the flat plain on the exposed continental shelf was dominated by intrazonal communities such as halophyte grasslands and freshwater wetlands instead of zonal steppe or semi-arid desert.All above evidence demonstrated that the fundamental changes of pollen assemblage and their origins in Okinawa Trough since^200 ka BP were affected by combine factors including the coastline position and climate fluctuation.Moreover,the substantial shortening of distance between shoreline and the Okinawa Trough driven by orbital insolation cycles was clearly indicated by the pollen spectra,whereas the source-area climate signal of the pollen record was largely weakened. | ZHENG Zhuo HUANG KangYou DENG Yun CAO LingLong YU ShaoHua Jean-Pierre SUC Serge BERNE Franois GUICHARD | 2013 | Science China Earth Sciences2013，56，10： | 11 |
| 5 | Onco-miR-24 regulates cell growth and apoptosis by targeting BCL2L11 in gastric cancer显示文摘胃的癌症是世界范围的最普通的恶意之一;然而,在 tumorigenesis 的分子的机制仍然需要探索。BCL2L11 属于 BCL-2 家庭,并且充当内在的 apoptotic 串联的一个中央管理者并且调停房间 apoptosis。尽管 miRNAs 被报导了涉及癌症开发的每个阶段,在 GC 的 miR-24 的角色还没被报导。在现在的学习,当 BCL2L11 的表示在 GC 的肿瘤纸巾被禁止时, miR-24 被发现起来调整。研究从在 vitro 并且在显示出的 vivo,那 miR-24 调整 BCL2L11 表示由与 mRNA 的 3UTR 直接有约束力,因此支持房间生长,移植当禁止房间 apoptosis 时。因此, miR-24 是能是为未来的潜在的药目标的新奇 onco-miRNA 临床的使用。 | Haiyang Zhang Jingjing Duan Yanjun Qu Ting Deng Rui Liu Le Zhang Ming Bai Jialu Li Tao Ning Shaohua Ge Xia Wang ZhenzhenWang~ Qian Fan Hongli Li Guoguang Ying Dingzhi Huang Yi Ba | 2016 | Protein & Cell2016，7，2： | 11 |
| 6 | treatment of swine wastewater in aerobic granular reactors: comparison of different seed granules as factors显示文摘使成粒状过程,药品化学药品性质,污染移动能力和有不同喂废水的氧气的小粒的细菌的社区(合成废水, R1;猪废水, R2 ) ,并且在对待猪废水的长期的操作反应堆的小粒的二种类型的一些参数的变化趋势在这个实验被调查。结果显示有合成废水的氧气的使成粒状在 R1 与猪废水和那完整的使成粒状相比有更快的率, R2 分别地在第 30 天和第 39 白天被到达。然而,尽管 feed 废水也在使成粒状过程期间在生物资源部分和氧气的小粒的细胞外的聚合物质上有明显的效果,这些性质在长期的操作以后在类似的水平留下了。而且,一个类似的增加趋势能也在反应堆,和 organics 的平均特定的移动率以氧气的小粒的氮移动效率被观察,在不变的阶段的氨氮为 R1 是 35.33 mgg 1 VSS 和 51.46 mgg 1 VSS ,并且为 R2 的 35.47 mgg 1 VSS 和 51.72 mgg 1 VSS 分别地。另外,在细菌的差异的移动发生在使成粒状过程,而在氧气的小粒的反应堆的细菌的社区没被种子小粒在长期的操作以后影响。 | Lin LIU Qiyu YOU Valerie GIBSON Xu HUANG Shaohua CHEN Zhilong YE Chaoxiang LIU | 2015 | Frontiers of Environmental Science & Engineering2015，9，6： | 9 |
| 7 | Overview of China's Antarctic research progress 1984–2016显示文摘It is more than 30 years since the first Chinese National Antarctic Research Expedition(CHINARE) landed in Antarctica in 1984, representing China's initiation in polar research. This review briefly summarizes the Chinese Antarctic scientific research and output accomplished over the past 30 years. The developments and progress in Antarctic research and the enhancement of international scientific cooperation achieved through the implementation of the CHINARE program have been remarkable. Since the 1980 s, four permanent Chinese Antarctic research stations have been established successively and 33 CHINAREs have been completed. The research results have been derived from a series of spatiotemporal observations in association with various projects and multidisciplinary studies in the fields of oceanography, glaciology, geology, geophysics, geochemistry, atmospheric science, upper atmospheric physics, Antarctic astronomy, biology and ecology, human medicine, polar environment observation, and polar engineering. | CHEN Liqi LIU Xiaohan BIAN Lingen CHEN Bo HUANG Hongliang HU Hongqiao LUO Wei SHI Guitao SHI Jiuxin XU Chengli YANG Guang ZHAO Yue ZHANG Shaohua | 2017 | Advances in Polar Science2017，28，3： | 9 |
| 8 | The origin, diversification and adaptation of a major mangrove clade (Rhizophoreae) revealed by whole-genome sequencing显示文摘Mangroves invade some very marginal habitats for woody plants—at the interface between land and sea.Since mangroves anchor tropical coastal communities globally, their origin, diversification and adaptation are of scientific significance, particularly at a time of global climate change. In this study, a combination of single-molecule long reads and the more conventional short reads are generated from Rhizophora apiculata for the de novo assembly of its genome to a near chromosome level. The longest scaffold, N50 and N90 for the R. apiculata genome, are 13.3 Mb, 5.4 Mb and 1.0 Mb, respectively. Short reads for the genomes and transcriptomes of eight related species are also generated. We find that the ancestor of Rhizophoreae experienced a whole-genome duplication ~70 Myrs ago, which is followed rather quickly by colonization and species diversification. Mangroves exhibit pan-exome modifications of amino acid(AA) usage as well as unusual AA substitutions among closely related species. The usage and substitution of AAs, unique among plants surveyed, is correlated with the rapid evolution of proteins in mangroves. A small subset of these substitutions is associated with mangroves' highly specialized traits(vivipary and red bark) thought to be adaptive in the intertidal habitats. Despite the many adaptive features, mangroves are among the least genetically diverse plants, likely the result of continual habitat turnovers caused by repeated rises and falls of sea level in the geologically recent past. Mangrove genomes thus inform about their past evolutionary success as well as portend a possibly difficult future. | Shaohua Xu Ziwen He Zhang Zhang Zixiao Guo Wuxia Guo Haomin Lyu Jianfang Li Ming Yang Zhenglin Du Yelin Huang Renchao Zhou Cairong Zhong David E. Boufford Manuel Lerdau Chung-I Wu Norman C. Duke Suhua Shi | 2017 | National Science Review2017，4，5： | 7 |
| 9 | A Hybrid MCDM Approach Based on ANP and TOPSIS for Facility Layout Selection显示文摘Facility layout selection is a multi-criteria decision making (MCDM) problem,since it has a strategic impact on the efficiency of manufacturing system.In view of the interdependency among selection criteria,analytic network process (ANP) is proposed to analyze the structure of the facility layout selection problem and determine the weights for each criterion.A network structure is constructed that shows all elements and clusters and their interactions.Limit priorities are also calculated which help decision maker evaluate the relative importance among criterion in the alternative selection process.Moreover,a hybrid MCDM approach that employs ANP and technique for order preference by similarity to an ideal solution (TOPSIS)method to rank the optimal facility layout alternatives.Finally,an application of a new aeronautic component assembly workshop facility layout selection is conducted.To further illustrate the advantage of the proposed approach,the difference between ANP-TOPSIS and AHP-TOPSIS methods are compared and discussed.Results have demonstrated the effectiveness and feasibility of the proposed method. | Zha Shanshan Guo Yu Huang Shaohua Tang Pengzhou | 2018 | Transactions of Nanjing University of Aeronautics and Astronautics2018，35，6： | 7 |
| 10 | Evolution of Tectonic Uplift, Hydrocarbon Migration, and Uranium Mineralization in the NW Junggar Basin: An Apatite Fission-Track Thermochronology Study显示文摘The Mesozoic–Cenozoic tectonic movement largely controls the northwest region of the Junggar Basin(NWJB), which is a significant area for the exploration of petroleum and sandstone-type uranium deposits in China. This work collected six samples from this sedimentary basin and surrounding mountains to conduct apatite fission track(AFT) dating, and utilized the dating results for thermochronological modeling to reconstruct the uplift history of the NWJB and its response to hydrocarbon migration and uranium mineralization. The results indicate that a single continuous uplift event has occurred since the Early Cretaceous, showing spatiotemporal variation in the uplift and exhumation patterns throughout the NWJB. Uplift and exhumation initiated in the northwest and then proceeded to the southeast, suggesting that the fault system induced a post spread-thrust nappe into the basin during the Late Yanshanian. Modeling results indicate that the NWJB mountains have undergone three distinct stages of rapid cooling: Early Cretaceous(ca. 140–115 Ma), Late Cretaceous(ca. 80–60 Ma), and Miocene–present(since ca. 20 Ma). These three stages regionally correspond to the LhasaEurasian collision during the Late Jurassic–Early Cretaceous(ca. 140–125 Ma), the Lhasa-Gandise collision during the Late Cretaceous(ca. 80–70 Ma), and a remote response to the India-Asian collision since ca. 55 Ma, respectively. These tectonic events also resulted in several regional unconformities between the J3/K1, K2/E, and E/N, and three large-scale hydrocarbon injection events in the Piedmont Thrust Belt(PTB). Particularly, the hydrocarbon charge event during the Early Cretaceous resulted in the initial inundation and protection of paleo-uranium ore bodies that were formed during the Middle–Late Jurassic. The uplift and denudation of the PTB was extremely slow from 40 Ma onward due to a slight influence from the Himalayan orogeny. However, the uplift of the PTB was faster after the Miocene, which led to re-uplift and exposure at the surface during the Quaternary, resulting in its oxidation and the formation of small uranium ore bodies. | QIN Mingkuan HUANG Shaohua HE Zhongbo XU Qiang SONG Jiye LIU Zhangyue GUO Qiang | 2018 | Acta Geologica Sinica(English Edition)2018，92，5： | 7 |
| 11 | Surface sulfurization activating hematite nanorods for efficient photoelectrochemical water splitting显示文摘Surface treatment is an effective method to improve the photoelectrochemical(PEC) performance of photoelectrodes. Herein, we introduced a novel strategy of surface sulfurization to modify hematite(a-Fe2 O3)nanorods grown in an aqueous solution, which triggered encouraging improvement in PEC performances.In comparison to the solution-grown pristine a-Fe2 O3 nanorod photoanode that is PEC inefficient and always needs high temperature(>600 °C) activation, the surface sulfurized a-Fe2 O3 nanorods show photocurrent density increased by orders of magnitude, reaching 0.46 mA cmà2 at 1.23 V vs. RHE(reversible hydrogen electrode) under simulated solar illumination. This improvement in PEC performances should be attributed to the synergy of the increased carrier density, the reduced surface charge carrier recombination and the accelerated water oxidation kinetics at the a-Fe2 O3/electrolyte interface, as induced by the incorporation of S ions and the formation of multi-state S species(Fe-Sx-Oy) at the surface of a-Fe2 O3 nanorods. This study paves a new and facile approach to activate a-Fe2 O3 and even other metal oxides as photoelectrodes for improved PEC water splitting performances, by engineering the surface structure to relieve the bottlenecks of charge transfer dynamics and redox reaction kinetics at the electrode/electrolyte interface. | Lianlian Mao Yu-Cheng Huang Yanming Fu Chung-Li Dong Shaohua Shen | 2019 | Science Bulletin2019，64，17： | 6 |
| 12 | Validation and target gene screening of hsa-miR-205 in lung squamous cell carcinoma显示文摘 | Huang Wei Jin Yi Yuan Yunfeng Bai Chunxue Wu Ying Zhu Hongguang Lu Shaohua | 2014 | Chinese Medical Journal2014，，2： | 6 |
| 13 | Growth and Optical Applications of Centimeter-Long ZnO Nanocombs显示文摘Ultralong ZnO nanocombs have been synthesized on silicon substrates with a high growth rate of~7μm/s using a simple“thermal evaporation and condensation”method promoted by Cu catalysts.The lengths of the ZnO nanocombs range from several millimeters to more than one centimeter and the diameters of the branches are about 300 nm.The growth mechanism of the ultralong nanocombs and the catalytic behavior of the copper are discussed.The nanocombs were readily separated and their applications as optical polarizer and grating were investigated.The results show that the ultralong ZnO nanocombs can act as effective optical components in miniaturized integrated optics systems. | Ke Yu Qiuxiang Zhang Jin Wu Lijun Li Yuʼe Xu Shaohua Huang Ziqiang Zhu | 2008 | Nano Research2008，1，3： | 4 |
| 14 | Multistage Enrichment of the Sawafuqi Uranium Deposit: New Insights into Sandstone-hosted Uranium Deposits in the Intramontane Basins of Tian Shan, China显示文摘Meso-Cenozoic intracontinental orogenic processes in the Tian Shan orogenic belt have significant effect on the sandstone-hosted uranium deposits in the intramontane basins and those adjacent to the orogen. The Sawafuqi uranium deposit, which is located in the South Tian Shan orogenic belt, is investigated to reveal the relationships between uranium mineralization and orogenies. Recent exploration results show that the Sawafuqi uranium deposit has tabular, stratiform, quasi-stratiform, and lens-like orebodies and various geological characteristics different from typical interlayer oxidation zone sandstone-hosted uranium deposits. Systematic studies of ore samples from the Sawafuqi uranium deposit using a variety of techniques, including thin section observation, α-track radiograph, electron microprobe and scanning electron microscope, suggest that uranium mineralization is closely related to pyrite and organic matter. Mineralization-related alterations in the host rocks are mainly silicification and argillation including kaolinite, illite(and illite-smectite mixed layer) and chlorite. Tree stages of mineralization were identified in the Sawafuqi uranium deposit:(i) uranium-bearing detritus and synsedimentary initial pre-enrichment;(ii) interlayer oxidization zone uranium mineralization; and(iii) vein-type uranium mineralization. The synsedimentary uranium pre-enrichment represents an early uranium enrichment in the Sawafuqi uranium deposit, and interlayer oxidation zone uranium mineralization formed the main orebodies, which are superimposed by the vein-type uranium mineralization. Combining the results of this study with previous studies on the Meso-Cenozoic orogenies of South Tian Shan, it is proposed that the synsedimentary uranium pre-enrichment of the Sawafuqi uranium deposit was caused by Triassic Tian Shan uplift, and the interlayer oxidation zone uranium mineralization occurred during the Eocence-Oligocene period, when tectonism was relatively quiet, whereas the vein-type uranium mineralization took place in relation to the strong orogeny of South Tian Shan since Miocene. | LIU Zhangyue PENG Suping QIN Mingkuan LIU Hongxun HUANG Shaohua HE Zhongbo GUO Qiang XU Qiang SONG Jiye | 2017 | Acta Geologica Sinica(English Edition)2017，91，6： | 3 |
| 15 | Electron-Deficient Zn-N_(6) Configuration Enabling Polymeric Carbon Nitride for Visible-Light Photocatalytic Overall Water Splitting显示文摘Despite of suitable band structures for harvesting solar light and driving water redox reactions,polymeric carbon nitride(PCN)has suffered from poor charge transfer ability and sluggish surface reaction kinetics,which limit its photocatalytic activity for water splitting.Herein,atomically dispersed Zn-coordinated three-dimensional(3D)sponge-like PCN(Zn-PCN)is synthesized through a novel intermediate coordination strategy.Advanced characterizations and theoretical calculations well evidence that Zn single atoms are coordinated and stabilized on PCN in the form of Zn-N_(6) configura-tion featured with an electron-deficient state.Such an electronic configuration has been demonstrated contributive to promoted electron excitation,accelerated charge separation and transfer as well as reduced water redox barriers.Further benefited from the abundant surface active sites derived from the 3D porous structure,Zn-PCN realizes visible-light photocatalysis for overall water splitting with H_(2) and O_(2) simultaneously evolved at a stoichiometric ratio of 2:1.This work brings new insights into the design of novel single-atom photocatalysts by deepening the understanding of electronic configurations and reactive sites favorable to excellent photocatalysis for water splitting and related solar energy conversion reactions. | Daming Zhao Yiqing Wang Chung-Li Dong Fanqi Meng Yu-Cheng Huang Qinghua Zhang Lin Gu Lan Liu Shaohua Shen | 2022 | Nano-Micro Letters2022，14，12： | 2 |
| 16 | Measurement of a Three-dimensional Gas Temperature Field with Holographic Interferometry显示文摘MeasurementofaThree-dimensionalGasTemperatureFieldwithHolographicInterferometry￥CHENShaohua(YibinTeacher'sCollege,Yibin644007... | CHEN Shaohua(Yibin Teacher’s College, Yibin 644007, CHN)ZHAO Xuxin HUANG Suyi SHI Dufang(Huazhong University of Science and Technology, Wuhan 430074, CHN) | 1996 | Semiconductor Photonics and Technology1996，2，1： | 2 |
| 17 | miRNA27a Is a Biomarker for Predicting Chemosensitivity and Prognosis in Metastatic or Recurrent Gastric Cancer显示文摘 | Dingzhi Huang Haiyan Wang Rui Liu Hongli Li Shaohua Ge Ming Bai Ting Deng Guangyu Yao Yi Ba | 2014 | J. Cell. Biochem2014，，3： | 2 |
| 18 | Embryonic senescent cells re-enter cell cycle and contribute to tissues after birth显示文摘 | Yi Li Huan Zhao Xiuzhen Huang Juan Tang Shaohua Zhang Yan Li Xiuxiu Liu Lingjuan He Zhengyu Ju Kathy O. Lui Bin-Zhou | 2018 | Cell Research2018，28，7： | 2 |
| 19 | Practice and exploration of educational innovation in the teaching process of anatomy显示文摘In the advent of knowledge economy and information society,the society urgently needs talents with high-quality,creativity and comprehensive development.School education plays an extremely important role in educating creative innovation. | Liu Hongfu Liang Shaohua Zhang Luping Zhao Dongmei Huang Fei | 2012 | 重庆医学2012，41，25： | 2 |
| 20 | NMR Studies on the Interaction between Oncogene RET G-Quadruplex and Berberine显示文摘of main observation and conclusion RET G-quadruplex DNA(G4-DNA)is formed in the promoter region of RET protein,which is involved in the initiation and progression of human cancers.Berberine inhibits cancer cell growth through interactions with RET G4-DNA,but how it binds to RET G4-DNA remains unknown.Previously,we reported that colchicine selectively bound to RET G4-DNA,but the structural basis of its binding selectivity is still unclear.Here,mainly by NMR,we demonstrated how berberine bound to RET G4-DNA in a means different from colchicine,and implied several key determinants for small molecules specifically binding to one G4-DNA. | Fei Wang Chunxi Wang Yaping Liu Wenxian Lan Renxiao Wang Shaohua Huang Chunyang Cao | 2020 | Chinese Journal of Chemistry2020，38，12： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员