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4篇 您的检索式:作者名="Rongkun Xu"
    题名 作者 年代 出处 被引量
1A point mutation of PRL gene in pituitary prolactin- secreting adenoma induced by 17-β-estradiol in SD rats显示文摘Animal model bearing pituitary prolactin-secreting adenomas (prolactinoma) induced by 17-β-estradiol (E2) in both eutopic pituitary and ectopic pituitary grafted under the renal capsule was generated. Northern blotting assay indicated that PRL mRNA level in eutopic prolactinomas was higher than that in normal pituitaries and ectopic prolactinomas (P<0.05 - 0.01). By polymerase chain reaction (PCR)-single-strand conformation polymorphism (SSCP) analysis and DNA sequencing, a point mutation from C to A occurring at -36 nt in proximal promoter of rat PRL (rPRL) gene was found only in eutopic prolactinomas. No base change was detected in ectopic prolactinomas. Fusion gene transfection assay in vitro exhibited increased activity of the mutant promoter derived from eutopic prolactinoma (P<0.01). These data suggested that the base change in the proximal promoter of rPRL gene may be associated with hyperexpression of rPRL gene in eutopic prolactinomas. The pathogenesis of eutopic and ectopic prolactinomasXuemei Wu Rongkun Xu 2000Chinese Science Bulletin2000,45,5:4
2Experimental investigation of Z-pinch radiation source for indirect drive inertial confinement fusion显示文摘Z-pinch dynamic hohlraums(ZPDHs)could potentially be used to drive inertial confinement fusion targets.Double-or multishell capsules using the technique of volume ignition could exploit the advantages of ZPDHs while tolerating their radiation asymmetry,which would be unacceptable for a central ignition target.In this paper,we review research on Z-pinch implosions and ZPDHs for indirect drive targets at the Institute of Nuclear Physics and Chemistry,China Academy of Engineering Physics.The characteristics of double-shell targets and the associated technical requirements are analyzed through a one-dimensional computer code developed from MULTI-IFE.Some key issues regarding the establishment of suitable sources for dynamic hohlraums are introduced,such as soft X-ray power optimization,novel methods for plasma profile modulation,and the use of thin-shell liner implosions to inhibit the generation of prior-stagnated plasma.Finally,shock propagation and radiation characteristics in a ZPDH are presented and discussed,together with some plans for future work.Zhenghong Li Zhen Wang Rongkun Xu Jianlun Yang Fan Ye Yanyun Chu Zeping Xu Faxin Chen Shijian Meng Jianmin Qi Qinyuan Hu Yi Qin Jiaming Ning Zhanchang Huang Linbo Li Shuqing Jiang 2019Matter and Radiation at Extremes2019,4,4:1
3Hexarelin suppresses high lipid diet and vitamin D 3 -induced atherosclerosis in the rat显示文摘Jinjiang Pang Qihua Xu Xiangbin Xu Hongchao Yin Rongkun Xu Shu Guo Wei Hao Luya Wang Chen Chen Ji-Min Cao 2009Peptides2009,,4:1
4Experimental investigation of the ribbon-array ablation process显示文摘Li Zhenghong Xu Rongkun Chu Yanyun 2013Phys Plasmas2013,20,03:1
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