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| 1 | miR-145 improves metabolic inflammatory disease through multiple pathways显示文摘Chronic inflammation plays a pivotal role in insulin resistance and type 2 diabetes,yet the mechanisms are not completely understood.Here,we demonstrated that serum LPS levels were significantly higher in newly diagnosed diabetic patients than in normal control.miR-145 level in peripheral blood mononuclear cells decreased in type 2 diabetics.LPS repressed the transcription of miR-143/145 cluster and decreased miR-145 levels.Attenuation of miR-145 activity by anti-miR-145 triggered liver inflammation and increased serum chemokines in C57BL/6 J mice.Conversely,lentivirus-mediated miR-145 overexpression inhibited macrophage infiltration,reduced body weight,and improved glucose metabolism in db/db mice.And miR-145 overexpression markedly reduced plaque size in the aorta in ApoE−/−mice.Both OPG and KLF5 were targets of miR-145.miR-145 repressed cell proliferation and induced apoptosis partially by targeting OPG and KLF5.miR-145 also suppressed NF-κB activation by targeting OPG and KLF5.Our findings provide an association of the environment with the progress of metabolic disorders.Increasing miR-145 may be a new potential therapeutic strategy in preventing and treating metabolic diseases such as type 2 diabetes and atherosclerosis. | Min He Nan Wu Man Cheong Leong Weiwei Zhang Zi Ye Rumei Li Jinyang Huang Zhaoyun Zhang Lianxi Li Xiao Yao Wenbai Zhou Naijia Liu Zhihong Yang Xuehong Dong Yintao Li Lili Chen Qin Li Xuanchun Wang Jie Wen Xiaolong Zhao Bin Lu Yehong Yang Qinghua Wang Renming Hu | 2020 | Journal of Molecular Cell Biology2020，12，2： | 7 |
| 2 | Gene-lndexed Mutations in Maize显示文摘 | Xiaoduo Lu Jisheng Liu Wen Ren Qun Yang Zhenguang Chai Rumei Chen Lei Wang Jun Zhao Zhihong Lang Haiyang Wang Yunliu Fan Jiuran Zhao Chunyi Zhang | 2018 | Molecular Plant2018，11，3： | 4 |
| 3 | ZmGRAS11,transactivated by Opaque2,positively regulates kernel size in maize显示文摘Although the genetic basis for endosperm development in maize(Zea mays)has been well studied,the mechanism for coordinating grain filling with increasing kernel size remains elusive.Here,we report that increased kernel size was selected during modern breeding and identify a novel DELLA-like transcriptional regulator,ZmGRAS11,which positively regulates kernel size and kernel weight in maize.We find that Opaque2,a core transcription factor for zein protein and starch accumulation,transactivates the expression of Zm GRAS11.Our data suggest that the Opaque2-Zm GRAS11 module mediates synergistic endosperm enlargement with grain filling. | Ye Li Shuai Ma Qianqian Zhao Di Lv Baobao Wang Ke Xiao Jiameng Zhu Suzhen Li Wenzhu Yang Xiaoqing Liu Haiyang Wang Xiaojin Zhou Rumei Chen | 2021 | Journal of Integrative Plant Biology2021，63，12： | 3 |
| 4 | Enhanced Learning Resource Recommendation Based on Online Learning Style Model显示文摘Smart learning systems provide relevant learning resources as a personalized bespoke package for learners based on their pedagogical needs and individual preferences.This paper introduces a learning style model to represent features of online learners.It also presents an enhanced recommendation method named Adaptive Recommendation based on Online Learning Style(AROLS),which implements learning resource adaptation by mining learners’behavioral data.First,AROLS creates learner clusters according to their online learning styles.Second,it applies Collaborative Filtering(CF)and association rule mining to extract the preferences and behavioral patterns of each cluster.Finally,it generates a personalized recommendation set of variable size.A real-world dataset is employed for some experiments.Results show that our online learning style model is conducive to the learners’data mining,and AROLS evidently outperforms the traditional CF method. | Hui Chen Chuantao Yin Rumei Li Wenge Rong Zhang Xiong Bertrand David | 2020 | Tsinghua Science and Technology2020，25，3： | 3 |
| 5 | Investigation of acid black 1 adsorption onto amino-polysaccharides显示文摘 | Cheng Rumei Jiang Zhiping Ou Shengju | 2009 | Polymer Bulletin2009，62，1： | 1 |
| 6 | Habitat utilization by ovipositing females and larvae of the Marsh fritillary (Euphydryas aurinia) in a mosaic of meadows and croplands显示文摘 | Wenhua Liu Yifei Wang Rumei Xu | 2006 | Journal of Insect Conservation2006，，4： | 1 |
| 7 | Transgenic maize plants expressing a fungal phytase gene显示文摘 | Rumei Chen Guangxing Xue Ping Chen Bin Yao Wenzhu Yang Qianli Ma Yunliu Fan Zuoyu Zhao Mitchell C. Tarczynski Jinrui Shi | 2008 | Transgenic Research2008，，4： | 1 |
| 8 | Targeted delivery of large fusion protein into hippocampal neurons by systemic administration显示文摘 | Lixin Xiang Rumei Zhou Ailing Fu Xingran Xu Yuqi Huang Changhua Hu | 2011 | Journal of Drug Targeting2011，，8： | 1 |
| 9 | Combustion parameters of gaseous epoxypropane/air in a confined vessel 显示文摘 | Zhang Qi Li Wei Tan Rumei | 2013 | Fuel2013，105，2： | 1 |
| 10 | Transgenic maize plants expressing a fungal phytase gene显示文摘 | Rumei Chen Guangxing Xue Ping Chen Bin Yao Wenzhu Yang Qianli Ma Yunliu Fan Zuoyu Zhao Mitchell C. Tarczynski Jinrui Shi | 2008 | Transgenic Research2008，，4： | 1 |
| 11 | Effects of humidity on minimum ignition energy of gaseous epoxypropane/air mixtures显示文摘 | Qi Zhang Rumei Tan Ying Huang Huimin Liang | 2012 | Journal of Loss Prevention in the Process Industries2012，，6： | 1 |
| 12 | Application of ditlfiuearbamate modified starch for dyes removal from aqueous solutions 显示文摘 | Rumei Cheng 13o Xiang Yijiu Li | 2011 | Journal of Hazardous Materials2011，188，13： | 1 |
| 13 | Equilibrium and Molecular Mechanism of Anionic Dyes Adsorption onto Copper (11) Complex of Dithioearbamate- Modified Starch 显示文摘 | Rumei Cheng Shengju Ou Bo Xiang Yijiu Li Qiangqiang Liao | 2010 | Langmuir2010，26，2： | 1 |
| 14 | Journal of Hazardous Materials 显示文摘 | Cheng Rumei Xiang Bo Li Yijiu Zhang Mingzhen | 2011 | 188(112/3): 254-2602011，188，1123： | 1 |
| 15 | Adsorption Behavior of Hexavalent Chromium on Synthesized Ethylenediamine Modified Starch显示文摘 | Cheng Rumei Ou Shengju Xiang Bo | 2009 | J Polym Res2009，，16： | 1 |
| 16 | Impact of Economic Development Levels and Disaster Types on the Short-Term Macroeconomic Consequences of Natural Hazard-Induced Disasters in China显示文摘The relationship between natural hazard-induced disasters and macroeconomic growth has been examined widely on global and national scales, but little research has been focused on the subnational level, especially in China.We examined the impacts of natural hazard-induced disasters on the regional growth in China based on subnational panel data for the period from 1990 to 2016. First, we used the number of people affected and the direct economic losses as the measures of the scale of disasters. Then, we used the direct damages of meteorological disasters and earthquakes as disaster measures separately to examine the impacts of different disaster types. Finally, we performed intraregional effects regressions to observe the spatial heterogeneity within the regions. The results show that the adverse short-term effects of disasters is most pronounced in the central region, while the direct damage of disasters is a positive stimulus of growth in the whole of China.However, this stimulus is observed in a lagged way and is reflected differently—meteorological disasters in central and eastern China and earthquakes in western China are related to regional growth. The results demonstrate that the short-term macroeconomic impacts of these disasters in the three geographical regions of China largely depend on regional economic development levels and the disaster types. | Rumei Tang Jidong Wu Mengqi Ye Wenhui Liu | 2019 | International Journal of Disaster Risk Science2019，10，3： | 1 |
| 17 | Constructing library networks wilh Chinese characteristics: bringing about society - wide sharing of information resources 显示文摘 | Guo Rumei | 2004 | The international Information & Library Review2004，，36： | 1 |
| 18 | The synthetic thyroid hormone, levothyroxine, protects cholinergic neurons in the hippocampus of naturally aged mice显示文摘The thyroid hormones, triiodothyronine and thyroxine, play important roles in cognitive function during the mammalian lifespan. However, thyroid hormones have not yet been used as a therapeutic agent for normal age-related cognitive deficits. In this study, CD-1 mice(aged 24 months) were intraperitoneally injected with levothyroxine(L-T4; 1.6 μg/kg per day) for 3 consecutive months. Our findings revealed a significant improvement in hippocampal cytoskeletal rearrangement of actin and an increase in serum hormone levels of L-T4-treated aged mice. Furthermore, the survival rate of these mice was dramatically increased from 60% to 93.3%. The Morris water maze task indicated that L-T4 restored impaired spatial memory in aged mice. Furthermore, level of choline acetyltransferase, acetylcholine, and superoxide dismutase were increased in these mice, thus suggesting that a possible mechanism by which L-T4 reversed cognitive impairment was caused by increased activity of these markers. Overall, supplement of low-dosage L-T4 may be a potential therapeutic strategy for normal age-related cognitive deficits. | Ailing Fu Rumei Zhou Xingran Xu | 2014 | Neural Regeneration Research2014，9，8： | 1 |
| 19 | 查看详情显示文摘 | Cheng Rumei Ou Sbengju Li Mengjie | | 0，，： | 1 |
| 20 | Intracavity biosensor based on the Nd:YAG waveguide laser: tumor cells and dextrose solutions显示文摘This work demonstrates the Nd:YAG waveguide laser as an efficient platform for the bio-sensing of dextrose solutions and tumor cells. The waveguide was fabricated in an Nd:YAG crystal with the cooperation of ultrafast laser writing and ion irradiation. The laser oscillation in the Nd:YAG waveguide is ultrasensitive to the external environment of the waveguide. Even a weak disturbance leads to a large variation of the output power of the laser.According to this feature, an Nd:YAG waveguide coated with graphene and WSe_2 layers is used as substrate for the microfluidic channel. When the microflow crosses the Nd:YAG waveguide, the laser oscillation in the waveguide is disturbed and induces fluctuation of the output laser. According to the fluctuation, the microflow is detected with a sensitivity of 10 mW/RIU. | GUANHUA LI HUIYUAN LI RUMEI GONG YANG TAN JAVIER RODRíGUEZ VáZQUEZ DE ALDANA YUPING SUN FENG CHEN | 2017 | Photonics Research2017，5，6： | 1 |
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