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| 1 | Outcome of multimodal MRI-guided intravenous thrombolysis in patients with stroke with unknown time of onset显示文摘Objective Intravenous tissue plasminogen activator(tPA)is the standard therapy for patients with acute ischaemic stroke(AIS)within 4.5 hours of onset.Recent trials have expanded the endovascular treatment window to 24 hours.We investigated the efficacy and safety of using multimodal MRI to guide intravenous tPA treatment for patients with AIS of unknown time of onset(UTO).Methods Data on patients with AIS with UTO and within 4.5 hours of onset were reviewed.Data elements collected and analysed included:demographics,National Institutes of Health Stroke Scale(NIHSS)score at baseline and 2 hours,24 hours,7 days after thrombolysis and before discharge,the modified Rankin Scale(mRS)score at 3 months after discharge,imaging findings and any adverse event.results Forty-two patients with UTO and 62 in control group treated within 4.5 hours of onset were treated with intravenous tPA.The NIHSS scores after thrombolysis and/or before discharge in UTO group were significantly improved compared with the baseline(p<0.05).Between the two groups,no significant differences in NIHSS score were observed(p>0.05).Utilising the non-inferiority test,to compare mRS scores(0-2)at 3 months between the two groups,the difference was 5.2%(92%CI,OR 0.196).Patients in the UTO group had mRS scores of 0-2,which were non-inferior to the control group.Their incidence of adverse events was similar.Conclusions Utilising multimodal MRI to guide intravenous only thrombolysis for patients with AIS with UTO was safe and effective.In those patients with AIS between 6 and 24 hours of time of onset but without large arterial occlusion,intravenous thrombolysis could be considered an option. | Jie Zhao Hongmei Zhao Runtao Li Jiangtao Li Chang Liu Juan Lv Yanan Li Wei Liu Dongpu Ma Huaihai Hao Xinguang Xiao Junzhong Liu Yongfeng Yin Rongli Liu Qiaoyan Yu Yingjie Wei Pengyan Li Yue Wang Runqing Wang | 2019 | Stroke & Vascular Neurology2019，4，1： | 8 |
| 2 | A prediction model of NH3 concentration for swine house in cold region based on Empirical Mode Decomposition and Elman neural network显示文摘In order to improve the accuracy and reliability of ammonia(NH3)concentration prediction,which can provides a support to the ventilation control strategy,so as to reduce the impact of NH3 on the health and productivity of swine,this paper proposed an NH3 concentration prediction method based on Empirical Mode Decomposition(EMD)and Elman neural network modelling.The NH3 concentration and other four environmental parameters including temperature,humidity,carbon dioxide and light intensity were decomposed into several different time-scale intrinsic mode functions(IMFs).Then,the Elman neural network prediction model was used to predict each IMF.The predicted NH3 was obtained by reconstructing all the IMFs by EMD.The results show that for the proposed method,the determination coefficient between the predicted and real measured value is 0.9856,the Mean Absolute Error is 0.7088 ppm,the Root Mean Square Error is 0.9096 ppm,and the Mean Absolute Percentage Error is 0.41%.Compared with the Elman neural network,the proposed method has a good improvement in the accuracy,and provide effective parameters for the environmental monitoring of the swine house and the regulation of the NH3 concentration. | Weizheng Shen Xiao Fu Runtao Wang Yanling Yin Yan Zhang Udaybeer Singh Bilegtsaikhan Lkhagva Jian Sun | 2019 | Information Processing in Agriculture2019，6，2： | 4 |
| 3 | Geochronology, geochemistry and Hf isotopes of andesites in the Sandaowanzi gold deposit(Great Xing’an Range, NE China): implications for petrogenesis, tectonic setting,and mineralization显示文摘The Sandaowanzi gold deposit is an extremely Au-rich deposit in the Northern Great Hinggan Range in recent years.Zircon U-Pb geochronology,Hf isotope analysis,and the geochemistry of andesites of the Longjiang Formation from the Sandaowanzi gold deposit were used to investigate the origin,magmatic evolution as well as mineralization and tectonic setting of the Early Cretaceous epithermal gold deposits in the northern Great Hinggan Range area.Zircon U-Pb dating reveals an emplacement age of 123.4±0.3 Ma,indicating that the andesites of the Sandaowanzi gold deposit was formed during the Early Cretaceous.The andesites are enriched in light rare earth elements relative to heavy rare earth elements and have weak negative Eu anomalies(δEu=0.76-0.90).The rocks are also enriched in large-ion lithophile elements,such as Rb,Ba,Th,U,and K,and depleted in the high-field-strength elements,such as Nb,Ta,and P.These characteristics are typical of volcanic rocks related to subduction.Igneous zircons from the andesite samples have relatively homogeneous Hf isotope ratios,176Hf/177Hf values of 0.282343-0.282502,εHf(t)values of-12.58 to-6.95,and two-stage model ages(TDM2)of 1743-1431 Ma.The characteristics of the andesites of the Longjiang Formation are consistent with derivation from partial melting of enriched mantle wedge metasomatized by subducted-slab-derived fluids.These rocks formed in an extensional environment associated with the closure of the Mongol-Okhotsk Ocean and subduction of the Paleo-Pacific Plate.Mineralization occurred towards the end of volcanism,and the magmatic activity and mineralization are products of the same geodynamic setting. | Runtao Yu Bile Li Fengyue Sun Zhihua Li Huawei Li Yufan Shi | 2021 | Acta Geochimica2021，40，2： | 2 |
| 4 | Assessment of dairy cow feed intake based on BP neural network with polynomial decay learning rate显示文摘To overcome the shortcomings of traditional dairy cow feed intake assessment model andBP neural network, this paper proposes a method of optimizing BP neural network usingpolynomial decay learning rate, taking the cow’s body weight, lying duration, lying times,walking steps, foraging duration and concentrate-roughage ratio as input variables andtaking the actual feed intake is the output variable to establish a dairy cow feed intakeassessment model, and the model is trained and verified by experimental data collectedon site. For the sake of comparative study, feed intake is simultaneously assessed by SVRmodel, KNN logistic regression model, traditional BP neural network model, and multilayerBP neural network model. The results show that the established BP model using the polynomial decay learning rate has the highest assessment accuracy, the MSPE, RMSE, MAE,MAPE and R2 are 0.043 kg2/d and 0.208 kg/d, 0.173 kg/d, 1.37% and 0.94 respectively. Compared with SVR model and KNN mode, the RMSE value reduced by 43.9% and 26.5%, it isalso found that the model designed in this paper has many advantages in comparison withthe BP model and multilayer BP model in terms of precision and generalization. Therefore,this method is ready to be applied for accurately evaluating the dairy cow feed intake, andit can provide theoretical guidance and technical support for the precise-feeding and canalso be of high significance in the improvement of dairy precise-breeding. | Weizheng Shen Gen Li Xiaoli Wei Qiang Fu Yonggen Zhang Tengyu Qu Congcong Chen Runtao Wang | 2022 | Information Processing in Agriculture2022，9，2： | 2 |
| 5 | In vitro screening of reversible and time-dependent inhibition on CYP3A by TM208 and TM209 in rat liver microsomes显示文摘TM208 and TM209,dithiocarbamate derivatives with potential anti-cancer effects,were evaluated in reversible and time-dependent cytochrome P450(CYP)3A inhibition assays in rat liver microsomes using testosterone as probe substrate.Both compounds were found to be weak reversible inhibitors and moderate mechanism-based inhibitors of rat CYP3A.For reversible inhibition on rat CYP3A,the Ki values of competitive inhibition model were 12.10±1.75 and 13.94±1.31 μM,respectively.For time-dependent inhibition,the inactivation constants(K_(l))were 31.93±12.64 and 32.91±15.58 μM,respectively,and the maximum inactivation rates(kinact)were 0.0349770.0069 and 0.0725970.0172 min^(-1) respectively.These findings would provide useful in vitro information for future in vivo DDI studies on TM208 or TM209。 | Miaoran Ning Liang Li Jian Li Zaiquan Li Runtao Li Tianyan Zhou Wei Lu | 2012 | Acta Pharmaceutica Sinica B2012，2，2： | 1 |
| 6 | Oxymatrine,themain alkaloid component of Sophora roots,protectsheart against arrhythmias in rats显示文摘 | Runtao G Guo D Jianqbo Y | 2011 | Planta Med2011，77，3： | 1 |
| 7 | Tasks-Oriented Joint Resource Allocation Scheme for the Internet of Vehicles with Sensing, Communication and Computing Integration显示文摘With the development of artificial intelligence(AI)and 5G technology,the integration of sensing,communication and computing in the Internet of Vehicles(Io V)is becoming a trend.However,the large amount of data transmission and the computing requirements of intelligent tasks lead to the complex resource management problems.In view of the above challenges,this paper proposes a tasks-oriented joint resource allocation scheme(TOJRAS)in the scenario of Io V.First,this paper proposes a system model with sensing,communication,and computing integration for multiple intelligent tasks with different requirements in the Io V.Secondly,joint resource allocation problems for real-time tasks and delay-tolerant tasks in the Io V are constructed respectively,including communication,computing and caching resources.Thirdly,a distributed deep Q-network(DDQN)based algorithm is proposed to solve the optimization problems,and the convergence and complexity of the algorithm are discussed.Finally,the experimental results based on real data sets verify the performance advantages of the proposed resource allocation scheme,compared to the existing ones.The exploration efficiency of our proposed DDQN-based algorithm is improved by at least about 5%,and our proposed resource allocation scheme improves the m AP performance by about 0.15 under resource constraints. | Jiujiu Chen Caili Guo Runtao Lin Chunyan Feng | 2023 | China Communications2023，20，3： | 1 |
| 8 | PrM and cellbinding domains of the dengue virus E protion显示文摘 | SongLi Wang Runtao He Robert Anderson | 1999 | J Virology Vol1999，73，3： | 1 |
| 9 | An Adaptive Estimating Detaipreserving Filter for Image Processing显示文摘 | Li Xiangji Ding Runtao | 1998 | Transactions on Tianjin University1998，4，2： | 1 |
| 10 | Oxymatrine, the main alkaloid component of Sophora roots, protects heart against arrhythmias in rats显示文摘 | RUNTAO G GUO D JIANQBO Y | 2011 | Planta Med2011，77，3： | 1 |
| 11 | An adaptive estimating detailpreserving filter for image processing 显示文摘 | Li Xiangji Ding Runtao | 1998 | Transactions on Tianjin University1998，4，2： | 1 |
| 12 | Oxymatrine, the main al- kaloid component of Sophora roots, protects heart against arrhythmias in rats 显示文摘 | Runtao G Guo D Jiangbo Y | 2011 | Planta Med2011，77，3： | 1 |
| 13 | Propylene oxide assisted one-pot, tandem synthesis of substituted-1,3,4-oxadiazole-2(3 H )-ones in water显示文摘 | Xu Yan Shuo Zhou Yuanqiang Wang Zemei Ge Tieming Cheng Runtao Li | 2012 | Tetrahedron2012，，38： | 1 |
| 14 | Oxymatrine, the main alkaloid component of Sophora roots, protects heart against arrhythmias in rats显示文摘 | Runtao G Guo D Jianqbo Y | 2011 | Planta Med2011，77，3： | 1 |
| 15 | High-performance thin-layer chromatographic fingerprints of isoflavonoids for distinguishing between Radix Puerariae Lobate and Radix Puerariae Thomsonii显示文摘 | CHEN Sibao LIU Heping TIAN Runtao | | 0，，01： | 1 |
| 16 | Analysis of multiplex PCR fragments with PMMA microchip显示文摘 | Liu Dayu Zhou Xiaomian Zhong Runtao | 2006 | Talanta2006，68，3： | 1 |
| 17 | Propylene oxide assisted one-pot, tandem synthesis of substituted-1,3,4-oxadiazole-2(3 H )-ones in water显示文摘 | Xu Yan Shuo Zhou Yuanqiang Wang Zemei Ge Tieming Cheng Runtao Li | 2012 | Tetrahedron2012，，38： | 1 |
| 18 | Species differentiation andquality assessment of Radix Paeoniae Rubra(Chi-shao)by means ofhigh-performance liquid chromatographic fingerprint显示文摘 | XU Shunjun LIU Yang TIAN Runtao | 2009 | Journal of Chro-matography A2009，1216，11： | 1 |
| 19 | Coenzyme A-acylating aldehyde dehydrogenase from Clostridium beijerinckii NRRL B592显示文摘 | Y Runtao Chen J S | 1990 | Appl Envir Micro1990，56，9： | 1 |
| 20 | Oxymatrine,the main alkaloid component of Sophora roots,protects heart against arrhythmias in rats显示文摘 | Runtao G | 2011 | Planta Med2011，77，3： | 1 |
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