|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Outcome of multimodal MRI-guided intravenous thrombolysis in patients with stroke with unknown time of onset显示文摘Objective Intravenous tissue plasminogen activator(tPA)is the standard therapy for patients with acute ischaemic stroke(AIS)within 4.5 hours of onset.Recent trials have expanded the endovascular treatment window to 24 hours.We investigated the efficacy and safety of using multimodal MRI to guide intravenous tPA treatment for patients with AIS of unknown time of onset(UTO).Methods Data on patients with AIS with UTO and within 4.5 hours of onset were reviewed.Data elements collected and analysed included:demographics,National Institutes of Health Stroke Scale(NIHSS)score at baseline and 2 hours,24 hours,7 days after thrombolysis and before discharge,the modified Rankin Scale(mRS)score at 3 months after discharge,imaging findings and any adverse event.results Forty-two patients with UTO and 62 in control group treated within 4.5 hours of onset were treated with intravenous tPA.The NIHSS scores after thrombolysis and/or before discharge in UTO group were significantly improved compared with the baseline(p<0.05).Between the two groups,no significant differences in NIHSS score were observed(p>0.05).Utilising the non-inferiority test,to compare mRS scores(0-2)at 3 months between the two groups,the difference was 5.2%(92%CI,OR 0.196).Patients in the UTO group had mRS scores of 0-2,which were non-inferior to the control group.Their incidence of adverse events was similar.Conclusions Utilising multimodal MRI to guide intravenous only thrombolysis for patients with AIS with UTO was safe and effective.In those patients with AIS between 6 and 24 hours of time of onset but without large arterial occlusion,intravenous thrombolysis could be considered an option. | Jie Zhao Hongmei Zhao Runtao Li Jiangtao Li Chang Liu Juan Lv Yanan Li Wei Liu Dongpu Ma Huaihai Hao Xinguang Xiao Junzhong Liu Yongfeng Yin Rongli Liu Qiaoyan Yu Yingjie Wei Pengyan Li Yue Wang Runqing Wang | 2019 | Stroke & Vascular Neurology2019，4，1： | 8 |
| 2 | Direct growth of single-walled carbon nanotubes on substrates显示文摘As one of the most promising candidate material for next generation electronic devices,the reliable and controllable synthesis of high quality single-walled carbon nanotubes(SWNTs) has long been an essential and important issue in the field.Direct growth of SWNTs on flat substrates by chemical vapor deposition(CVD) process is the best way to obtain SWNTs because it is immediately ready for building nano-devices.The orientation of the SWNTs has been well controlled by gas flow or substrate lattice during the CVD growth process.The chirality and structure control of SWNTs is still a big challenge.However,the conductivity selective growth has already partially succeeded.New catalysts have been explored to obtain SWNTs of higher quality.Along with the further progress in the study of the SWNT growth,the precise control over the orientation,position and conductivity of SWNTs is expected to meet the requirements of carbon-based nanoelectronics. | PENG Fei LIU Yu CUI RongLi GAO DongLiang YANG Feng LI Yan | 2012 | Chinese Science Bulletin2012，57，2： | 5 |
| 3 | Opening of the inward rectifier potassium channel alleviates maladaptive tissue repair following myocardial infarction显示文摘里面的整流器钾水流(IK1 ) 的激活隧道被报导了与室的心律不齐的抑制被联系。在这研究,我们测试了与 zacopride (ZAC ) IK1 隧道开在心肌的梗塞以后涉及织物修理的调整的假设。Sprague-Dawley 老鼠服从于冠的动脉结扎, ZAC intraperitoneally 被管理(15 諟?牦吗? | Chengfang Liu Enli Liu Tiane Luo Weifang Zhang Rongli He | 2016 | Acta Biochimica et Biophysica Sinica2016，48，8： | 4 |
| 4 | Kinetics study on leaching of rare earth and aluminum from polishing powder waste using hydrochloric acid显示文摘In this study,a novel hydrometallurgical process consisting of hydrochloric acid three-stage countercurrent leaching and solvent extraction was proposed to recover rare earth oxide(REO)from the rare earth polishing powder waste(REPPW).The effects of HCl concentration,liquid-solid ratio(L/S ratio),temperature and time on the leaching yields of rare earths(in REO)and aluminum(in Al2O3)were studied.The result shows that the leaching yields of REO and Al2O3 are 90.96%and 43.89%respectively under the optimum leaching parameters of HCl concentration=8.00 mol/L,L/S ratio=4 mL/g,leaching temperature=353 K and leaching time=180 min.Meanwhile,the leaching kinetics of REO and Al2O3 were investigated in this study.The leaching behaviors of REO and Al2O3 follow a shrinking sphere/core model and the general leaching process is controlled by the surface chemical reaction.The leaching activation energies of REO and Al2O3 are 9.86 and 13.68 kJ/mol,respectively.The leaching yield of each substance in three-stage countercurrent leaching is improved substantially compared with single-stage leaching,with a change from 90.96%to 95.38%for REO and from 43.89%to 46.22%for Al2O3,respectively.Especially,the total concentration of REO in three-stage countercurrent leaching solution is greatly increased to above 300 g/L,and the acidity of which is decreased to ca.pH=2,which is conducive to subsequent solvent extraction directly.High purity REO(99.92%)is obtained by solvent extraction separation,oxalate precipitation and calcination.The total recovery yield of REO is 85.13%. | Xitao Wu Zhijian Wang Chuping Xia Xuefeng Shi Tianzong Luo Xinjun Bao Rongli Liu Shengzhong Xie | 2020 | Journal of Rare Earths2020，38，9： | 3 |
| 5 | Loss of Lkb1 impairs Treg function and stability to aggravate graft-versus-host disease after bone marrow transplantation显示文摘Accumulating evidence suggests that a reduction in the number of Foxp3^(+) regulatory T cells(Tregs)contributes to the pathogenesis of acute graft-versus-host disease(aGVHD),which is a major adverse complication that can occur after allogeneic hematopoietic stem cell transplantation(allo-HSCT).However,the precise features and mechanism underlying the defects in Tregs remain largely unknown.In this study,we demonstrated that Tregs were more dramatically decreased in bone marrow compared with those in peripheral blood from aGVHD patients and that bone marrow Treg defects were negatively associated with hematopoietic reconstitution.Tregs from aGVHD patients exhibited multiple defects,including the instability of Foxp3 expression,especially in response to IL-12,impaired suppressor function,decreased migratory capacity,and increased apoptosis.Transcriptional profiling revealed the downregulation of Lkb1,a previously identified critical regulator of murine Treg identity and metabolism,and murine Lkb1-regulated genes in Tregs from aGVHD patients.Foxp3 expression in human Tregs could be decreased and increased by the knockdown and overexpression of the Lkb1 gene,respectively.Furthermore,a loss-of-function assay in an aGVHD murine model confirmed that Lkb1 deficiency could impair Tregs and aggravate disease severity.These findings reveal that Lkb1 downregulation contributes to multiple defects in Tregs in human aGVHD and highlight the Lkb1-related pathways that could serve as therapeutic targets that may potentially be manipulated to mitigate aGVHD. | Xiuhua Su Qianqian Wang Wei Guo Xiaolei Pei Qing Niu Maolan Liu Yuanyuan Liu Song Chen Sizhou Feng Yi He Donglin Yang Rongli Zhang Qiaoling Ma Weihua Zhai Aiming Pang Jialin Wei Yong Huang Yuechen Luo Mingzhe Han Xiaoming Feng Erlie Jiang | 2020 | Cellular & Molecular Immunology2020，17，5： | 3 |
| 6 | Preparation of horizontally aligned single-walled carbon nanotubes with floating catalyst显示文摘A strategy to prepare horizontally aligned single-walled carbon nanotubes(SWNTs) at moderate temperatures(≤600 ℃) were developed.Using ferocene as the catalyst precursor,Fe nanoparticles are formed in the gaseous phase and catalyze the nucleation and growth of SWNTs in situ.Then the resultant SWNTs are deposited onto the substrates downstream and aligned by the surface lattice of the ST-cut single crystal quartz.The preparation of SWNT arrays at moderate temperatures is important for combining the tube growth with device fabrication. | Rongli Cui Xiulan Zhao Ruoming Li Yu Liu Da Luo Feng Yang Yan Li | 2017 | Science China Chemistry2017，60，4： | 2 |
| 7 | Different mechanisms of improving CH_(3)NH_(3)PbI_(3) perovskite solar cells brought by fluorinated or nitrogen doped graphdiyne显示文摘Fluorinated and nitrogen-doped graphdiyne(F/N-GDY)have been used in the active layer of perovskite solar cells(PSCs)for the first time.The introduction of heteroatoms turns out to be an effective method for boosted solar cells performance,which increases by 32.8%and 33.0%,better than the pristine or GDY doped PSCs.The enhanced performance can be attributed firstly to the superiority of F/N-GDY originated from the unique structure and optoelectronic properties of GDY.Then,both can further reduce surface defects and improve surface and bulk crystallinity than pristine GDY.What's more,efficiency increase caused by F-GDY is mainly attributed to the improvement of fill factor(FF),while the higher short-circuit current(Jsc)plays more important role by N-GDY doping.Most importantly,the detailed mechanism brought about by doping of F-GDY or N-GDY is expounded by systematical characterizations,especially the synchrotron radiation technique.Doping of F-GDY causes Pb and forms new Pb-F bonds between F-GDY and Pb ions.Doping of N-GDY or GDY brings about Pb(N-GDY doping induces more deviation than that of GDY due to the participation of imine N),improving its electron density and conductivity. | Huan Huang Bing Liu Dan Wang Rongli Cui Xihong Guo Ying Li Shouwei Zuo Zi Yin Huanhua Wang Jing Zhang Hui Yuan Lirong Zheng Baoyun Sun | 2022 | Nano Research2022，15，1： | 2 |
| 8 | Risk factors associated with hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation显示文摘Hemorrhagic cystitis(HC)is a common complication of allogeneic hematopoietic stem cell transplantation(HSCT).The incidence is about 7%to 68%,and some patients have to suffer a long period of frequent,urgent,and painful urination,which brings great pain.This study aimed to analyze risk factors of HC and its effect on patient survival.We collected the medical records of 859 patients who underwent HSCT at our hospital between August 2016 and August 2020.Patients with and without HC were matched using propensity score matching at a 1:1 ratio based on sex,age,and diagnosis,and logistic regression analyses were used to identify factors associated with HC.We used Kaplan–Meier curves to analyze the survival rates of patients in the HC and non-HC groups.We also analyzed the relationship between BK viral load and the occurrence of HC using receiver operating characteristic curve(ROC)analysis.After propensity score matching,there were 131 patients each in the HC and non-HC groups.In the HC group,89 patients(67.9%)had mild HC(stage II°)and 43(32.1%)had severe HC(stage III–IV).The median interval between stem cell transplantation and HC development was 31(3–244)days.Univariate analysis indicated that donor age,hematopoietic stem cell source,HLA,acute graft-versus-host disease,busulfan,anti-thymocyte globulin(ATG),total body irradiation,cytomegalovirus(CMV)(urine),and BK polyomavirus(BKV)(urine)were significantly associated with HC.ATG,CMV(urine),and BKV(urine)were independent risk factors for HC based on the multivariate analysis.The Kaplan–Meier survival analysis showed no significant difference between the HC and non-HC groups(P=0.14).The 1-and 2-year survival rates in the HC group were 78.4%and 69.6%,respectively,and the corresponding rates in the non-HC group were 84.4%and 80.7%,respectively.ROC analysis indicated that a urine BKV load of 1×10^(7) copies/mL was able to stratify the risk of HC.In conclusion,when the BKV load is>1×10^(7),we needtobe aware of the potential for the development of HC. | Biao Shen Yueshen Ma Haixiao Zhang Mingyang Wang Jia Liu Jiaxin Cao Wenwen Guo Dan Feng Donglin Yang Rongli Zhang Xin Chen Qiaoling Ma Weihua Zhai Sizhou Feng Mingzhe Han Aiming Pang Erlie Jiang 无 | 2022 | Blood Science2022，4，2： | 2 |
| 9 | Study of preparation and modification for Dysprosium Cobalt Ferrite Magnetic Fluids显示文摘 | J1ANG Rongli ZHAO Wentao | 2004 | Journal Hunan University of Arts and Science2004，1，16： | 1 |
| 10 | One-pot synthesis of grass-like Fe 3 O 4 nanostructures by a novel microemulsion-assisted solvothermal method显示文摘 | Yanfen Li Rongli Jiang Tingyu Liu Hui Lv Lu Zhou Xiaoyu Zhang | 2013 | Ceramics International2013，，： | 1 |
| 11 | Risk factors for CMV infection within 100 days posttransplantation in patients with acute leukemia显示文摘Objective:To investigate the risk factors for cytomegalovirus(CMV)infection within 100 days and the relationship between early CMV infection and 1-year relapse for patients with acute leukemia following allogeneic hematopoietic stem cell transplantation(allo-HSCT).Methods:Three hundred fifty-nine patients with acute leukemia who received allo-HSCT at our center between January 2015 and January 2020 were retrospectively reviewed.Results:Of 359 patients,48.19%(173)patients experienced CMV infection within 100 days posttransplantation.In univariate and multivariate logistic analysis,haploidentical-related donor(HRD)(P<0.001;odds ratio[OR],5.542;95%confidence interval[CI],3.186–9.639),and ratio of CD3^(+)CD8^(+)cells in lymphocytes<14.825%(P<0.001;OR,3.005;95%CI,1.712–5.275)were identified as 2 independent risk factors.One-year relapse rate(RR)between the CMV infection group and the non-CMV infection group was not statistically significant(18.5%vs 19.9%,P=0.688).When we divided the total cohort into AML,ALL,and MAL subgroups,there were no significant differences as well(P=0.138;P=0.588;P=0.117;respectively).Conclusion:In conclusion,donor type(HRD)and the insufficient recovery of CD3^(+)CD8^(+)cells were independent risk factors for CMV infection within 100 days posttransplantation in patients with acute leukemia.CMV infection within 100 days did not influence the incidence of relapse in 1 year for patients with acute leukemia. | Juan Chen Aiming Pang Yuanqi Zhao Li Liu Runzhi Ma Jialin Wei Xin Chen Yi He Donglin Yang Rongli Zhang Weihua Zhai Qiaoling Ma Erlie Jiang Mingzhe Han Jiaxi Zhou Sizhou Feng | 2022 | Blood Science2022，4，3： | 0 |
| 12 | Highly delocalized endohedral metal in Gd@C2v(9)-C82 metallofullerenes co-crystallized with α-Se显示文摘 | Cheng Li Xuejiao J. Gao Huanli Yao Huan Huang Rongli Cui Xihong Guo Lele Zhang Bing Liu Binggang Xu Weiqun Shi Jinquan Dong Lai Feng Xingfa Gao Baoyun Sun | 2018 | Nano Research2018，11，4： | 0 |
| 13 | Chronicler of Hometown Celebrities显示文摘By the time Shangyu Hometown Celebrities Institute was set up in January 2001,Chen Qiuqiang had been looking into local celebrities for more than ten years. Shangyu is a county-level city in Shaoxing in eastern Zhejiang and hometown to a lot of national and regional celebrities. | Chen Rongli Liu Jinping | 2017 | 文化交流2017，，1： | 0 |
| 14 | The Tianlai Cylinder Pathfinder array: System functions and basic performance analysis显示文摘The Tianlai Cylinder Pathfinder is a radio interferometer array designed to test techniques for 21 cm intensity mapping in the post-reionization Universe,with the ultimate aim of mapping the large scale structure and measuring cosmological parameters such as the dark energy equation of state.Each of its three parallel cylinder reflectors is oriented in the north-south direction,and the array has a large field of view.As the Earth rotates,the northern sky is observed by drift scanning.The array is located in Hongliuxia,a radio-quiet site in Xinjiang,and saw its first light in September 2016.In this first data analysis paper for the Tianlai cylinder array,we discuss the sub-system qualification tests,and present basic system performance obtained from preliminary analysis of the commissioning observations during 2016-2018.We show typical interferometric visibility data,from which we derive the actual beam profile in the east-west direction and the frequency band-pass response.We describe also the calibration process to determine the complex gains for the array elements,either using bright astronomical point sources,or an artificial on site calibrator source,and discuss the instrument response stability,crucial for transit interferometry.Based on this analysis,we find a system temperature of about 90 K,and we also estimate the sensitivity of the array. | JiXia Li ShiFan Zuo FengQuan Wu YouGang Wang JuYong Zhang ShiJie Sun YiDong Xu ZiJie Yu Reza Ansari YiChao Li Albert Stebbins Peter Timbie YanPing Cong JingChao Geng Jie Hao QiZhi Huang JianBin Li Rui Li DongHao Liu YingFeng Liu Tao Liu John PMarriner ChenHui Niu Ue-Li Pen Jeffery BPeterson HuLi Shi Lin Shu YaFang Song HaiJun Tian GuiSong Wang QunXiong Wang RongLi Wang WeiXia Wang Xin Wang KaiFeng Yu Jiao Zhang BoQin Zhu JiaLu Zhu XueLei Chen | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，12： | 0 |
| 15 | The Study on the Gas Sensitivity of the One-Dimensional ZnO显示文摘One-dimensional (1D) ZnO was prepared through hydrothermal synthesis by cetyltrimethylammonium bromide (CTAB) controling its morphology.The products were characterized by X-ray diffraction (XRD),transmission electron microscopy (TEM) and scanning electron microscopy (SEM).The sintered gas sensor was prepared using ZnO nanorods and its gas sensitivity was measured in static gas atmosphere.The result showed that the ZnO nanorods had lower working temperature than granulated ZnO and had very good sensitivity to 10μg/g trimethylamine (TMA),methanol,ammonia, acetone and ethanol at the working temperature of 170℃.SEM picture revealed that there were many multi-pores in the surface of the sensors.These multi-pores might help to absorb gases and improve the gas sensitivity. | Qun Xiang Rongli Liu Liyi Shi Zhiyin Ni Qingyi Pan | 2006 | 稀有金属材料与工程2006，35，A03： | 0 |
| 16 | Some properties of superprocesses conditioned on non-extinction显示文摘We simply call a superprocess conditioned on non-extinction a conditioned superprocess. In this study, we investigate some properties of the conditioned superprocesses (subcritical or critical). Firstly, we give an equivalent description of the probability of the event that the total occupation time measure on a compact set is finite and some applications of this equivalent description. Our results are extensions of those of Krone (1995) from particular branching mechanisms to general branching mechanisms. We also prove a claim of Krone for the cases of d = 3, 4. Secondly, we study the local extinction property of the conditioned binary super-Brownian motion {Xt, P μ∞ }. When d = 1, as t goes to infinity, Xt/√t converges to ηλ in weak sense under P μ∞ , where η is a nonnegative random variable and λ is the Lebesgue measure on R. When d 2, the conditioned binary super-Brownian motion is locally extinct under P μ∞ . | LIU RongLi REN YanXia | 2009 | Science China Mathematics2009，52，4： | 0 |
| 17 | Decellularized Extracellular Matrix Containing Electrospun Fibers for Nerve Regeneration:A Comparison Between Core–Shell Structured and Preblended Composites显示文摘Advanced biomaterial-based strategies for treatment of peripheral nerve injury require precise control over both topological and biological cues for facilitating rapid and directed nerve regeneration.As a highly bioactive and tissue-specifc natural material,decellularized extracellular matrix(dECM)derived from peripheral nerves(decellularized nerve matrix,DNM)has drawn increasing attention in the feld of regenerative medicine,due to its outstanding capabilities in facilitating neurite outgrowth and remyelination.To induce and maintain sufcient topological guidance,electrospinning was conducted for fabrication of axially aligned nanofbers consisting of DNM and poly(ε-caprolactone)(PCL).Core–shell structured fbers were prepared by coaxial electrospinning using DNM as the shell and PCL as the core.Compared to the aligned electrospun fbers using preblended DNM/PCL,the core–shell structured fbers exhibited lower tensile strength,faster degradation,but considerable toughness for nerve guidance conduit preparation and relatively intact fbrous structure after long-term degradation.More importantly,the full DNM surface coverage of the aligned core–shell fbers efectively promoted axonal extension and Schwann cells migration.The DNM contents further triggered neurite bundling and myelin formation toward nerve fber maturation and functionalization.Herein,we not only pursue a multi-functional scafold design for nerve regeneration,a detailed comparison between core–shell structured and preblended electrospinning of DNM/PCL composites was also provided as an applicable paradigm for advanced tissue-engineered strategies using dECM-based biomaterials. | Rongli Deng Ziling Luo Zilong Rao Zudong Lin Shihao Chen Jing Zhou Qingtang Zhu Xiaolin Liu Ying Bai Daping Quan | 2022 | Advanced Fiber Materials2022，4，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员