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    题名 作者 年代 出处 被引量
15-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers显示文摘象 5-methylcytosine (5mC ) 和 5-hydroxymethylcytosine (5hmC ) 那样的 DNA 修正是知道在哺乳动物影响全球基因表示的 epigenetic 标记。在人的染色体,与基因表示的靠近的关联和高化学的稳定性给他们的流行,这些 DNA epigenetic 标记能为癌症用作理想的 biomarkers 诊断。利用一种高度敏感、选择的化学标记技术,我们这里报导在传播没有房间的 DNA ( cfDNA )并且在从最近与 colorectal 诊断的 260 个病人的一个队收集的配对的肿瘤和邻近的纸巾的 genomic DNA ( gDNA )的 5hmC 的染色体宽的介绍,胃,胰腺,从 90 个健康个人的肝或甲状腺癌症和正常纸巾。5hmC 主要在与开的染色质和容许的 histone 修正重合的 transcriptionally 活跃的区域被散布。柔韧的联系癌症的 5hmC 签名在 cfDNA 被识别为特定的癌症类型是特征的。传播 cfDNA 的 5hmC 底 biomarkers colorectal 和胃的癌症是高度预兆的并且比常规 biomarkers 优异并且比得上从织物活体检视的 5hmC biomarkers。因此,这新策略能从血样品的分析为癌症的诊断和预后导致有效、最低限度地侵略的方法的发展。Wenshuai Li Xu Zhang Xingyu Lu Lei You Yanqun Song Zhongguang Luo Jun Zhang Ji Nie Wanwei Zheng Diannan Xu Yaping Wang Yuanqiang Dong Shulin Yu Jun Hong Jianping Shi Hankun Hao Fen Luo Luchun Hua Peng Wang Xiaoping Qian Fang Yuan Lianhuan Wei Ming Cui Taiping Zhang Quan Liao Menghua Dai Ziwen Liu Ge Chen Katherine Meckel Sarbani Adhikari Guifang Jia Marc B Bissonnette Xinxiang Zhang Yupei Zhao Wei Zhang Chuan He Jie Liu 2017Cell Research2017,27,10:30
2Comparison of design of intraocular lens versus the material for PCO prevention显示文摘AIM: To evaluate the influence of different intraocular lens(IOL) designs made of PMMA on posterior capsular opacification(PCO) and compare with foldable designs.· METHODS: Phacoemulsification and IOL implantation was done in one eye of 24 New Zealand White rabbits, with IOL of two different designs (Square edged or round edge) and two different materials(PMMA or HEMA). After three months, the animals were sacrificed and enucleated. Evaluation of PCO included posterior view, migration of anterior capsular epithelial cells to the posterior capsule following epithelial-mesenchymal transition were assessed by staining the histological sections of posterior capsule by hematoxylin-eosin(HE) and Periodic acid- Schiff (PAS). The IOLs were extracted and stained with HE to evaluate the presence of adherent cells on the lens surface. · RESULTS: PCO was highest with round edged rigid lens. There was no significant difference in the PCO between the square edged PMMA and square edged foldable lens.· CONCLUSION: It is the design of the IOL not the material that offers protection on PCO formation.Sarbani Hazra Himangshu Palui Geeta K Vemuganti 2012International Journal of Ophthalmology(English edition)2012,5,1:5
3用于白内障超声乳化训练的活体白内障动物模型(英文)显示文摘目的:制备用于白内障超声乳化训练的活体白内障动物模型。方法:狗在全身麻醉下用26号带有斜面的针刺破左眼的晶状体前囊,制备白内障模型,形成白内障后,行超声乳化手术。结果:眼部检查显示晶状体后部皮质混浊开始于穿刺术后5~7d,并于术后75d白内障全部形成,在所有的白内障形成的眼上行超声乳化手术,并植入人工晶状体,所有的狗均恢复了视力。结论:考虑到无经验的眼科医生在行白内障超声乳化手术的初始阶段引起的巨大损失,我们认为这个活的动物模型明显优于目前用于训练超声乳化手术的尸体眼。Sarbani Hazra Dipak K De Arup K Bose Biswarup Roy 2008国际眼科杂志2008,8,6:2
4Induction of sister chromatid exchanges by cypermethrin and carbosulfan in bone marrow cells of mice in vivo显示文摘Sarbani Girl Anirudha Girl Gouri Dutt Sharma 2003Mutagenesis2003,18,1:1
5Clinical outcomes for nasopharyngeal cancer with intracranial extension after taxanebased induction chemotherapy and concurrent chemo-radiotherapy in the modern era显示文摘Objective:To evaluate the survival outcomes for a cohort of nasopharyngeal cancer with intracranial extension(ICE)treated with induction chemotherapy(ICT)followed by chemo-intensity-modulated radiotherapy(CTRT)at a tertiary cancer center.Methods:We retrospectively analyzed 45 patients with histologically proven,non-metastatic NPC with ICE treated at our institute between October 2008 and October 2016.Patients were classified as minor ICE or major ICE,based on the extent of ICE.All the patients received 2-3 cycles of a taxane-based ICT regimen followed by CTRT.Radiotherapy was delivered with'riskadapted'intensity-modulated radiotherapy(IMRT)technique in all patients.Results:After a median follow up of 45 months(range:8-113 months),the estimated 5-year DFS,LRFS,DMFS,and OS of the entire cohort was 58%,82%,67%and 74%respectively.On multivariate analysis,histological subtype was an independent predictor of LRFS,and age was an independent predictor of DFS.The extent of ICE showed only a trend towards worse DFS(P=0.06).None of the factors significantly predicted for DMFS or OS.Gender,N-stage,and response to ICT did not significantly affect any of the outcomes.Grade 2 or worse subcutaneous fibrosis was seen in 22%of patients and grade 2 or worse xerostomia was seen in 24%of patients at last follow up.Thirty-three percent of the patients developed clinical hypothyroidism at last follow up.None of the patients experienced any neurological or vascular complications.Conclusions:Taxane-based induction chemotherapy followed by chemo-intensity modulated radiotherapy resulted in excellent locoregional control and survival with acceptable toxicities in patients of nasopharyngeal cancer with intracranial extension.Distant metastasis continues to be the predominant problem in these patients.Sarbani Ghosh-Laskar Avinash Pilar Carlton Johnny Kumar Prabhash Amit Joshi Jai Prakash Agarwal Tejpal Gupta Ashwini Budrukkar Vedang Murthy Monali Swain Vanita Noronha Vijay Maruthi Patil Prathamesh Pai Deepa Nair Devendra Arvind Chaukar Shivakumar Thiagarajan Gouri Pantvaidya Anuja Deshmukh Pankaj Chaturvedi Sudhir Nair Anil D’Cruz 2020World Journal of Otorhinolaryngology-Head and Neck Surgery2020,6,1:1
6Assessmeat of DNA damage in peripheral blood lymphocytes of individuals susceptible to arsenic induced toxicity in West Bengal,India显示文摘Anamika Basua Arundhati Soma Sarbani Ghoshala 2005Toxicology Letters2005,159,:1
7Mutagenic Effects of Carbosulfan, a Carbamate Pesticide 显示文摘SARBANI G ANIRUDHA G GOURI D S et ol 2002Mutation Research2002,519,12:1
8Mutagenic effects of carbosulfan, a carbamate pesticide显示文摘Sarbani G Anirudha G Gouri DS 2002Mutat Res2002,519,:1
9Fetal ECG extraction from single-channel maternal ECG using singular value decomposition显示文摘PARTHA P K SARBANI P GOUTAM S 1997IEEE Transactions on Biomedical Engineering1997,44,1:1
10A stereocontrolled total synthesis of(±)-△2-cedrene显示文摘SARBANI D ASHUTOSH P DEBABRATA M 0,,25:1
11Multimodality Management of Esophageal Cancer显示文摘Pallavi Purwar Supriya Bambarkar Sabita Jiwnani George Karimundackal Sarbani Ghosh Laskar C. S. Pramesh 2014Indian Journal of Surgery2014,,6:1
12Transition-metal/Lewis Acid Free Synthesis of Acyl Benzothiophenes via C-C Bond Forming Reaction显示文摘Sarbani P Bindu P Dubey P K 2007Beilstein J Org Chem2007,3,35:1
13Re-irradiation in the management of isolated neck recurrences: Current status and recommendations显示文摘Supriya Chopra Tejpal Gupta Jai Prakash Agarwal Ashwini Budrukkar Sarbani Ghosh-Laskar Ketayun Dinshaw 2006Radiotherapy and Oncology2006,,1:1
14Prognostic factors in oropharyngeal cancer – analysis of 627 cases receiving definitive radiotherapy显示文摘Jai Prakash Agarwal Indranil Mallick Ritu Bhutani Sarbani Ghosh-Laskar Tejpal Gupta Ashwini Budrukkar Vedang Murthy Manju Sengar Ketayun A. Dinshaw 2009Acta Oncologica2009,,7:1
15Author Correction: 5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers显示文摘In the initial published version of this article, there was a mistake in the P value for the correlation between gene-expression changes and 5 hmC changes in tumors. The correct P value should be same as the P value shown in Fig. S6A: 9.8?×?10?6 (mistakenly shown as “9.8?×?106” in the main text). This correction does not affect the description of results or the conclusions of this study, since the range of P value is between 0 and 1.Wenshuai Li Xu Zhang Xingyu Lu Lei You Yanqun Song Zhongguang Luo Jun Zhang Ji Nie Wanwei Zheng Diannan Xu Yaping Wang Yuanqiang Dong Shulin Yu Jun Hong Jianping Shi Hankun Hao Fen Luo Luchun Hua Peng Wang Xiaoping Qian Fang Yuan Lianhuan Wei Ming Cui Taiping Zhang Quan Liao Menghua Dai Ziwen Liu Ge Chen Katherine Meckel Sarbani Adhikari Guifang Jia Marc B Bissonnette Xinxiang Zhang Yupei Zhao Wei Zhang Chuan He Jie Liu 2019Cell Research2019,29,7:1
16Volumetric modulated arc radiotherapy for carcinomas of the oro-pharynx, hypo-pharynx and larynx: A treatment planning comparison with fixed field IMRT显示文摘Eugenio Vanetti Alessandro Clivio Giorgia Nicolini Antonella Fogliata Sarbani Ghosh-Laskar Jai Prakash Agarwal Ritu Raj Upreti Ashwini Budrukkar Vedang Murthy Deepak Dattatray Deshpande Shyam Kishore Shrivastava Ketayun Ardeshir Dinshaw Luca Cozzi 2009Radiotherapy and Oncology2009,,1:1
17局部麻醉对兔眼心反射和眼角膜愈合的影响(英文)显示文摘目的:在兔模型中利用局部麻醉来研究两种麻醉剂的眼心反射发生率及其预防,同时我们还研究了局部麻醉对角膜愈合的影响。方法:健康的成年新西兰白兔(雌雄皆有)48只,分成两组(A组和B组),分别用氯胺酮(A组,24例)、异丙酚(B组,24例)麻醉。在此双盲研究中,通过用或不用局部麻醉(40g/L利多卡因,5g/L盐酸丙美卡因,5g/L布比卡因)对眼睛的不同干预,记录各组眼心反射发生率。应用每种局部麻醉后,通过对眼睛的临床检查,组织病理学,胶原染色以及投射电子显微等方法对术后1d长达7d角膜毒性和愈合进行评估。结果:在氯胺酮的麻醉下未出现眼心反射,而在异丙酚的麻醉下,心率显著下降(P<0.01)。因此,局部麻醉可以成功地防止眼心反射的发生并且不影响角膜愈合。结论:局部麻醉没有任何局部副作用,可以被推荐用来预防眼心反射。Jay Singh Subhasis Roy Prasenjit Mukherjee Debajyoti Konar Aditya Konar Sarbani Hazra 2009国际眼科杂志2009,9,12:0
18Adaptive Execution of Jobs in Computational Grid Environment显示文摘In a computational grid,jobs must adapt to the dynamically changing heterogeneous environment with an objective of maintaining the quality of service.In order to enable adaptive execution of multiple jobs running concurrently in a computational grid,we propose an integrated performance-based resource management framework that is supported by a multi-agent system(MAS).The multi-agent system initially allocates the jobs onto different resource providers based on a resource selection algorithm.Later,during runtime,if performance of any job degrades or quality of service cannot be maintained for some reason(resource failure or overloading),the multi-agent system assists the job to adapt to the system. This paper focuses on a part of our framework in which adaptive execution facility is supported.Adaptive execution facility is availed by reallocation and local tuning of jobs.Mobile,as well as static agents are employed for this purpose.The paper provides a summary of the design and implementation and demonstrates the efficiency of the framework by conducting experiments on a local grid test bed.Sarbani Roy Nandini Mukherjee 2009Journal of Computer Science & Technology2009,24,5:0
19Evolving provenance in the Proterozoic Pranhita-Godavari Basin,India显示文摘The Pranhita-Godavari Basin in central eastern India is one of the Proterozoic 'Purana' basins of cratonic India.New geochronology demonstrates that it has a vast depositional history of repeated basin reactivation from the Palaeoproterozoic to the Mesozoic.U-Pb laser ablation inductively coupled plasma mass spectrometry dating of detrital zircons from two samples of the Somanpalli Group—a member of the oldest sedimentary cycle in the valley-constrains its depositional age to ~1620 Ma and demonstrates a tripartite age provenance with peaks at ~3500 Ma,~2480 Ma and ~1620 Ma,with minor age peaks in the Eoarchaean(~3.8 Ga) and at ~2750 Ma.These ages are consistent with palaeocurrent data suggesting a southerly source from the Krishna Province and Enderby Land in East Antarctica.The similarity in the maximum depositional age with previously published authigenic glauconite ages suggest that the origin of the Pranhita-Godvari Graben originated as a rift that formed at a high angle to the coeval evolving late Meosproterozoic Krishna Province as Enderby Land collided with the Dharwar craton of India.In contrast,detrital zircons from the Cycle III Sullavai Group red sandstones yielded a maximum depositional age of 970±20 Ma and had age peaks of ~2550 Ma,~1600 Ma and then a number of Mesoproterozoic detrital zircons terminating in three analyses at ~970 Ma.The provenance of these is again consistent with a southerly source from the Eastern Ghats Orogen and Antarctica.Later cycles of deposition include the overlying Albaka/Usur Formations and finally the late Palaeozoic to Mesozoic Gondwana Supergroup.Udeni Amarasinghe Asru Chaudhuri Alan S.Collins Gautam Deb Sarbani Patranabis-Deb 2015Geoscience Frontiers2015,6,3:0
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