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| 1 | Effect of Microstructure Refinement on the Strength and Toughness of Low Alloy Martensitic Steel显示文摘马氏体的微观结构在熄灭,有从 6 亩 m 到 199 亩 m 的优先的奥氏体谷物尺寸的 tempered 17CrNiMo6 钢被光金属组织学( OM )描绘了,与各种各样的优先的奥氏体谷物尺寸扫描电子显微镜学( SEM )和传动电子显微镜学( TEM ) .Theyield 强度和钢的坚韧被测试并且与微观结构特征相关。结果证明在 17CrNiMo6 钢的优先的奥氏体谷物尺寸和马氏体的包尺寸与收益强度跟随一种 Hall-Petch 关系。当优先的奥氏体谷物尺寸从 199 亩 m 被精制到 6 亩 m 时,收益强度由 235 MPa 增加了,当在 77 K 的 Charpy U槽口冲击能多于 8times 改善了时,显示那微观结构精炼在比在增加强度改进抵抗到劈开骨折是更有效的。破裂表面暗示为劈开骨折的联合起来的裂缝路径作为是包被识别。 | Chunfang WANG Maoqiu WANG Jie SHI Weijun HUI Han DONG | 2007 | Journal of Materials Science & Technology2007，23，5： | 50 |
| 2 | Recombinant CC16 protein inhibits the production of pro-inflammatory cytokines via NF-KB and p38 MAPK pathways in LPS-activated RAW264,7 macrophages显示文摘积累的证据显示克莱拉房间 protein-16 (CC16 ) 有反煽动性的功能,尽管深奥分子的小径完全没被阐明。这里,我们评估了效果肿瘤坏死因素 alpha (TNF-) 的表示上的 recombinant 老鼠 CC16 (rCC16 ) , interleukin-6 (IL-6 ) ,和在 lipopolysaccharide (LPS ) 的 IL-8 刺激了老鼠巨噬细胞(RAW264.7 房间) 并且探索了内在的分子的机制。rCC16 在两个禁止了导致 LPS 的 TNF- , IL-6,和 IL-8 表示,这被发现送信人 ribonucleicacid (mRNA ) 水平和蛋白质以一种集中依赖者方式铺平,由即时反向的 transcriptase 聚合酶链反应和连接酶的 immunosorbent 试金示威了。如此的镇压效果被 transcriptional 活动和原子因素(NF ) 的脱氧核糖核酸酸绑定活动的抑制伴随 -B 然而并非使活跃之物蛋白质(AP )-1。西方的污点分析进一步表明 rCC16 禁止了原子 NF-B 和 NF-B 禁止的蛋白质 IB,和 p38 的 cytosolic NF-B, phosphorylation 和减小的减小的增加激活 mitogen 的蛋白质 kinase (MAPK ) 依赖者由在它的 p65 子单元的 Ser276 的 phosphorylation 的 NF-B 激活。而且, rCC16 被发现没另外在c6月N终端 kinase ,c6月,或c-Jun.的原子 translocation 的 phosphorylation 上有效果,TNF-的减小, IL-6 ,并且 IL-8 被颠倒内长的uteroglobin有约束力的蛋白质的水平什么时候被 RNA 干扰在 对待rCC16 、 对待LPS 的 RAW264.7 房间减少。我们的数据建议 rCC16 由在 RAW264.7 房间使 NF-B 和 p38 MAPK 然而并非 AP-1 失去活性压制调停 LPS 的煽动性的调停人 TNF- , IL-6,和 IL-8 生产。 | Min Pang Yangyang Yuan Dong Wang Ting Li Dan Wang Xiaohong Shi Min Guo Chunfang Wang Xinri Zhang Guoping Zheng Baofeng Yu Hailong Wang | 2017 | Acta Biochimica et Biophysica Sinica2017，49，5： | 14 |
| 3 | Fine Mapping of RppP25, a Southern Rust Resistance Gene in Maize显示文摘Southern rust (Puccinia polysora Underw.) is a major disease that can cause severe yield losses in maize (Zea mays L.). In our previous study, a major gene RppP25 that confers resistance to southern rust was identified in inbred line P25. Here, we report the fine mapping and candidate gene analysis of RppP25 from the near-isogenic line F939, which harbors RppP25 in the genetic background of the susceptible inbred line F349. The inheritance of resistance to southern rust was investigated in the BC1F1 and BC3F1 populations, which were derived from a cross between F939 and F349 (as the recurrent parent). The 1:1 segregation ratio of resistance to susceptible plants in these two populations indicated that the resistance is controlled by a single dominant gene. Ten markers, including three simple sequence repeat (SSR) markers and seven insertion/deletion (InDel) markers, were developed in the RppP25 region. RppP25 was delimited to an interval between P091 and M271, with an estimated length of 40 kb based on the physical map of B73. In this region, a candidate gene was identified that was predicted to encode a putative nucleotide-binding site leucine-rich repeat (NBS-LRR) protein. Two co-segregated markers will aid in pyramiding diverse southern rust resistance alleles into elite materials, and thereby improve southern rust resistance worldwide. | Panfeng Zhao Guobin Zhang Xiaojun Wu Na Li Dianyi Shi Dengfeng Zhang Chunfang Ji Mingliang Xu Shoucai Wang | 2013 | Journal of Integrative Plant Biology2013，55，5： | 5 |
| 4 | Dynamic blood single-cell immune responses in patients with COVID-19显示文摘The 2019 coronavirus disease(COVID-19)outbreak caused by the SARS-CoV-2 virus is an ongoing global health emergency.However,the virus'pathogenesis remains unclear,and there is no cure for the disease.We investigated the dynamic changes of blood immune response in patients with COVID-19 at different stages by using 5'gene expression,T cell receptor(TCR),and B cell receptors(BCR)V(D)J transcriptome analysis at a single-cell resolution.We obtained single-cell mRNA sequencing(scRNA-seq)data of 341,420 peripheral blood mononuclear cells(PBMCs)and 185,430 donotypic T cells and 28,802 donotypic B cells from 25 samples of 16 patients with COVID-19 for dynamic studies.In addition,we used three control samples.We found expansion of dendritic cells(DCs),CD14+monocytes,and megakaryocytes progenitor cells(MP)/platelets and a reduction of naive CD4+T lymphocytes in patients with COVID-19,along with a significant decrease of CD8+T lymphocytes,and natural killer cells(NKs)in patients in critical condition.The type I interferon(IFN-I),mitogen-activated protein kinase(MAPK),and ferroptosis pathways were activated while the disease was active,and recovered gradually after patient conditions improved.Consistent with this finding,the mRNA level of IFN-I signal-induced gene IFI27 was significantly increased in patients with COVID-19 compared with that of the controls in a validation cohort that included 38 patients and 35 controls.The concentration of interferon-a(IFN-a)in the serum of patients with COVID-19 increased significantly compared with that of the controls in an additional cohort of 215 patients with COVID-19 and 106 controls,further suggesting the important role of the IFN-I pathway in the immune response of COVID-19.TCR and BCR sequences analyses indicated that patients with COVID-19 developed specific immune responses against SARS-CoV-2 antigens.Our study reveals a dynamic landscape of human blood immune responses to SARS-CoV-2 infection,providing clues for therapeutic potentials in treating COVID-19. | Lulin Huang Yi Shi Bo Gong Li Jiang Zhixin Zhang Xiaoqi Liu Jialiang Yang Yongquan He Zhilin Jiang Ling Zhong Juan Tang Chunfang You Qi Jiang Bo Long Tao Zeng Mei Luo Fanwei Zeng Fanxin Zeng Shuqiang Wang Xingxiang Yang Zhenglin Yang | 2021 | Signal Transduction and Targeted Therapy2021，6，4： | 4 |
| 5 | Statistical prediction of failure times under generalized progressive hybrid censoring in a simple step-stress accelerated competing risks model显示文摘Based on a simple step-stress accelerated competing risks model from generalized exponential distribution, the statistical prediction problem of unobserved failure times under generalized progressive hybrid censoring is investigated. Using the cumulative exposure model, maximum likelihood predictors, conditional median predictors, approximate prediction intervals and conditional prediction intervals of model parameters and unobserved competing failure times are obtained. To support and illustrate the prediction methods, an available dataset is analyzed and a simulation study is carried out. The numerical results of predictors of model parameters and competing failure times show that the prediction methods have a good performance. | Chunfang Zhang Yimin Shi | 2017 | Journal of Systems Engineering and Electronics2017，28，2： | 2 |
| 6 | Overexpression of DLC-1 induces cell apoptosis and proliferation inhibition in the renal cell carcinoma显示文摘 | Tao Zhang Jingcun Zheng Ning Jiang Guozeng Wang Quan Shi Chunfang Liu Yuan Lu | 2009 | Cancer Letters2009，，1： | 1 |
| 7 | Computer Simulation of Image Reconstruction by a New Frequency Spectrum Approach Algorithm显示文摘 | Chunfang Li Dufang Shi Yunshan Li | 2003 | SPIE2003，5058，： | 1 |
| 8 | Model,Tests and Application Design for Viscoelastic Dampers显示文摘 | Xu Zhaodong Wang Dengxiang Shi Chunfang | 2011 | Journal of Vibration and Control2011，17，9： | 1 |
| 9 | Effect of microstructural refinement on the toughness of low carbon martensitic steel显示文摘 | Wang Chunfang Wang Maoqiu Shi Jie | 2008 | Scripta Meterialia2008，58，： | 1 |
| 10 | Effect of microstructure on the toughness of low alloy martensitic steel显示文摘 | WANG Chunfang WANG Maoqiu SHI Jie | 2008 | Scripta Materialia2008，58，6： | 1 |
| 11 | Ultra-fast and high-efficient synthesis of caffeic acid phenethyl ester by microwave assistant ionic liquids catalysis显示文摘Caffeic acid phenethyl ester (CAPE), a natural and rare ingredient with several biological activities, was successfully synthesized from caffeic acid (CA) and phenylethanol (PE) by microwave assistant coupled with ionic liquids (ILs) catalysis. Four ILs, acted as both solvent and catalyst in this chemical synthesis, were optimized. Among them, [Bmim] [PF6] was the best with the highest CA conversion. 95% conversion was achieved under substrate molar ratio 4:1 (PE/CA, n/n), IL content 7:1 (IL/CA, w/w), microwave power 200 W, at 135 oC for 7 min. This study might be attributed to developing new chemical reaction system to produce caffeic acid derived esters. | Zhe Dong Shi Wang Mingming Zheng Chunfang Xu Fenghong Huang | 2017 | Oil Crop Science2017，2，4： | 0 |
| 12 | Fungal diversity notes 1512–1610: taxonomic and phylogenetic contributions on genera and species of fungal taxa显示文摘This article is the 14th in the Fungal Diversity Notes series,wherein we report 98 taxa distributed in two phyla,seven classes,26 orders and 50 families which are described and illustrated.Taxa in this study were collected from Australia,Brazil,Burkina Faso,Chile,China,Cyprus,Egypt,France,French Guiana,India,Indonesia,Italy,Laos,Mexico,Russia,Sri Lanka,Thailand,and Vietnam.There are 59 new taxa,39 new hosts and new geographical distributions with one new combination.The 59 new species comprise Angustimassarina kunmingense,Asterina lopi,Asterina brigadeirensis,Bartalinia bidenticola,Bartalinia caryotae,Buellia pruinocalcarea,Coltricia insularis,Colletotrichum fexuosum,Colletotrichum thasutense,Coniochaeta caraganae,Coniothyrium yuccicola,Dematipyriforma aquatic,Dematipyriforma globispora,Dematipyriforma nilotica,Distoseptispora bambusicola,Fulvifomes jawadhuvensis,Fulvifomes malaiyanurensis,Fulvifomes thiruvannamalaiensis,Fusarium purpurea,Gerronema atrovirens,Gerronema favum,Gerronema keralense,Gerronema kuruvense,Grammothele taiwanensis,Hongkongmyces changchunensis,Hypoxylon inaequale,Kirschsteiniothelia acutisporum,Kirschsteiniothelia crustaceum,Kirschsteiniothelia extensum,Kirschsteiniothelia septemseptatum,Kirschsteiniothelia spatiosum,Lecanora immersocalcarea,Lepiota subthailandica,Lindgomyces guizhouensis,Marthe asmius pallidoaurantiacus,Marasmius tangerinus,Neovaginatispora mangiferae,Pararamichloridium aquisubtropicum,Pestalotiopsis piraubensis,Phacidium chinaum,Phaeoisaria goiasensis,Phaeoseptum thailandicum,Pleurothecium aquisubtropicum,Pseudocercospora vernoniae,Pyrenophora verruculosa,Rhachomyces cruralis,Rhachomyces hyperommae,Rhachomyces magrinii,Rhachomyces platyprosophi,Rhizomarasmius cunninghamietorum,Skeletocutis cangshanensis,Skeletocutis subchrysella,Sporisorium anadelphiae-leptocomae,Tetraploa dashaoensis,Tomentella exiguelata,Tomentella fuscoaraneosa,Tricholomopsis lechatii,Vaginatispora favispora and Wetmoreana blastidiocalcarea.The new combination is Torula sundara.The 39 new records on hosts and geographical distribution comprise Apiospora guiyangensis,Aplosporella artocarpi,Ascochyta medicaginicola,Astrocystis bambusicola,Athelia rolfsii,Bambusicola bambusae,Bipolaris luttrellii,Botryosphaeria dothidea,Chlorophyllum squamulosum,Colletotrichum aeschynomenes,Colletotrichum pandanicola,Coprinopsis cinerea,Corylicola italica,Curvularia alcornii,Curvularia senegalensis,Diaporthe foeniculina,Diaporthe longicolla,Diaporthe phaseolorum,Diatrypella quercina,Fusarium brachygibbosum,Helicoma aquaticum,Lepiota metulispora,Lepiota pongduadensis,Lepiota subvenenata,Melanconiella meridionalis,Monotosporella erecta,Nodulosphaeria digitalis,Palmiascoma gregariascomum,Periconia byssoides,Periconia cortaderiae,Pleopunctum ellipsoideum,Psilocybe keralensis,Scedosporium apiospermum,Scedosporium dehoogii,Scedosporium marina,Spegazzinia deightonii,Torula fci,Wiesneriomyces laurinus and Xylaria venosula.All these taxa are supported by morphological and multigene phylogenetic analyses.This article allows the researchers to publish fungal collections which areimportant for future studies.An updated,accurate and timely report of fungus-host and fungus-geography is important.We also provide an updated list of fungal taxa published in the previous fungal diversity notes.In this list,erroneous taxa and synonyms are marked and corrected accordingly. | Ruvishika S.Jayawardena Kevin D.Hyde Song Wang Ya‑Ru Sun Nakarin Suwannarach Phongeun Sysouphanthong Mohamed A.Abdel‑Wahab Faten A.Abdel‑Aziz Pranami D.Abeywickrama Vanessa P.Abreu Alireza Armand AndréAptroot Dan‑Feng Bao Dominik Begerow Jean‑Michel Bellanger Jadson D.P.Bezerra Digvijayini Bundhun Mark S.Calabon Ting Cao Taimy Cantillo João LVRCarvalho Napalai Chaiwan Che‑Chih Chen Régis Courtecuisse Bao‑Kai Cui Ulrike Damm Cvetomir M.Denchev Teodor T.Denchev Chun Y.Deng Bandarupalli Devadatha Nimali Ide Silva Lidiane Ados Santos Nawal K.Dubey Sylvain Dumez Himashi SFerdinandez André L.Firmino Yusufon Gaforov Achala J.Gajanayake Deecksha Gomdola Sugantha Gunaseelan Shucheng‑He Zin H.Htet Malarvizhi Kaliyaperumal Martin Kemler Kezhocuyi Kezo Nuwan DKularathnage Marco Leonardi Ji‑Peng Li Chunfang Liao Shun Liu Michael Loizides Thatsanee Luangharn Jian Ma Hugo Madrid S.Mahadevakumar Sajeewa S.N.Maharachchikumbura Dimuthu S.Manamgoda María P.Martín Niranjan Mekala Pierre‑Arthur Moreau Yan‑Hong Mu Pasouvang Pahoua Dhandevi Pem Olinto L.Pereira Wiphawanee Phonrob Chayanard Phukhamsakda Mubashar Raza Guang‑Cong Ren Andrea C.Rinaldi Walter Rossi Binu C.Samarakoon Milan CSamarakoon Vemuri V.Sarma Indunil C.Senanayake Archana Singh Maria F.Souza Cristina M.Souza‑Motta Adriano A.Spielmann Wenxin Su Xia Tang XingGuo Tian Kasun M.Thambugala Naritsada Thongklang Danushka S.Tennakoon Nopparat Wannathes DingPeng Wei Stéphane Welti Subodini N.Wijesinghe Hongde Yang Yunhui Yang Hai‑Sheng Yuan Huang Zhang Jingyi Zhang Abhaya Balasuriya Chitrabhanu SBhunjun Timur S.Bulgakov Lei Cai Erio Camporesi Putarak Chomnunti Y.S.Deepika Mingkwan Doilom Wei‑Jun Duan Shi‑Ling Han Naruemon Huanraluek EBGareth Jones NLakshmidevi Yu Li Saisamorn Lumyong Zong‑Long Luo Surapong Khuna Jaturong Kumla Ishara S.Manawasinghe Ausana Mapook Wilawan Punyaboon Saowaluck Tibpromma Yong‑Zhong Lu JiYe Yan Yong Wang | 2022 | Fungal Diversity2022，，6： | 0 |
| 13 | Rapid Microwave Assisted Synthesis and Antiproliferative Evaluation of Novel Steroidal Thiazole Derivatives显示文摘Three series of novel steroidal thiazole derivatives were synthesized by microwave assisted one-potreaction from pregnenolone, testosterone and estrone, respectively. Their structures were characterized by IR, NMRand HRMS, and the antiproliferative activities of all the synthesized compounds against human cervical carcinoma(HeLa), human liver carcinoma(HepG2), human lung carcinoma(A549), nasopharyngeal carcinoma(CNE2) andnormal kidney epithelial cells(HEK293T) were screened. Among the compounds, 1-estron-17'-ylidene-2-[4'-(p-bromophenyl)-2'-thiazol]hydrazone(12) displayed distinct antiproliferative activity against all the tested cancercell lines and was almost inactive to normal kidney epithelial cells. | HUANG Yanmin ZHAO Dandan LIU Chang GAN Chunfang ZHAN Junyan LIN Qifu SHI Haixin CUI Jianguo | 2017 | Chemical Research in Chinese Universities2017，33，2： | 0 |
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