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| 1 | Nidus vespae protein inhibiting proliferation of HepG2 hepatoma cells through extracellular signal-regulated kinase signaling pathways and inducing G1 cell cycle arrest显示文摘蛋白质说出 NVP (1 ) 从巢 vespae 被孤立。T 他现在的学习的目的是阐明 NVP (1 ) 是否并且怎么调制 HepG2 房间的增长。在 6.6 μg/ml 的集中的 NVP (1 ) 能在阶段 G 1 逮捕房间周期并且禁止 cyclinB, cyclinD1 和 cyclinE 的 mRNA 表示。NVP (1 ) 压制了 cdk2 蛋白质表示,但是增加了 p27 和 p21 蛋白质表示。然而, NVP (1 ) 没改变 p16 蛋白质表示层次。NVP (1 ) 在由原子染色质冷凝作用显示了的 HepG2 房间支持了 apoptosis,并且另外,表明小径的细胞外的调整信号的 kinase (英皇家空军之阶级最低之兵) 被激活。而且,当 HepG2 房间是有英皇家空军之阶级最低之兵禁止者 PD98059 的 pretreated 时,津贴蛋白质表示水平被稀释。这些结果证明 NVP (1 ) 通过表明小径的英皇家空军之阶级最低之兵禁止 HepG2 的增长。NVP (1 ) 能是为肝癌症的潜在的药。 | Changdong Wang Peng Chen Hongjuan Jin Xu Yan Lu Gan Yi Li Shiyi Zhou Junli Chang Yuesheng Wang Guangxiao Yang Guangyuan He | 2008 | Acta Biochimica et Biophysica Sinica2008，40，11： | 11 |
| 2 | Dynamically controlling terahertz wavefronts with cascaded metasurfaces显示文摘Dynamically controlling terahertz(THz)wavefronts in a designable fashion is highly desired in practice.However,available methods working at microwave frequencies do not work well in the THz regime due to lacking suitable tunable elements with submicrometer sizes.Here,instead of locally controlling individual meta-atoms in a THz metasurface,we show that rotating different layers(each exhibiting a particular phase profile)in a cascaded metadevice at different speeds can dynamically change the effective Jonesmatrix property of the whole device,thus enabling extraordinary manipulations on the wavefront and polarization characteristics of a THz beam impinging on the device.After illustrating our strategy based on model calculations,we experimentally demonstrate two proof-of-concept metadevices,each consisting of two carefully designed all-silicon transmissive metasurfaces exhibiting different phase profiles.Rotating two metasurfaces inside the fabricated devices at different speeds,we experimentally demonstrate that the first metadevice can efficiently redirect a normally incident THz beam to scan over a wide solid-angle range,while the second one can dynamically manipulate both the wavefront and polarization of a THz beam.Our results pave the way to achieving dynamic control of THz beams,which is useful in many applications,such as THz radar,and bio-and chemical sensing and imaging. | Xiaodong Cai Rong Tang Haoyang Zhou Qiushi Li Shaojie Ma Dongyi Wang Tong Liu Xiaohui Ling Wei Tan Qiong He Shiyi Xiao Lei Zhou | 2021 | Advanced Photonics2021，3，3： | 8 |
| 3 | High-performance meta-devices based on multilayer meta-atoms:interplay between the number of layers and phase coverage显示文摘Transmissive metasurfaces have provided an efficient platform to manipulate electromagnetic(EM)waves, but previously adopted multilayer meta-atoms are too thick and/or the design approach fully relies on brute-force simulations without physical understandings. Here, based on coupled-mode theory(CMT) analyses on multilayer meta-atoms of distinct types, it is found that meta-atoms of a specific type only allows the phase coverage over a particular range, thus suitable for polarization-control applications.However, combinations of meta-atoms with distinct types are necessary for building ultra-thin wavefront-control meta-devices requiring 360° phase coverage. Based on these physical understandings,high-efficiency meta-atoms are designed/fabricated, and used to construct three typical meta-devices,including quarter-and half-wave plates and a beam deflector. Our results elucidate the physics underlying the interplay between thicknesses and performances of transmissive metasurfaces, which can guide the realizations of miniaturized transmissive meta-devices in different frequency domains. | Bowen Yang Tong Liu Huijie Guo Shiyi Xiao Lei Zhou | 2019 | Science Bulletin2019，64，12： | 5 |
| 4 | Scatterings from surface plasmons to propagating waves at plasmonic discontinuities显示文摘Surface plasmon polaritons (SPPs) and their low-frequency counterpart spoof SPPs have attracted intensive interests in sciences [1,2], due to their unprecedented capabilities to confine electromagnetic (EM) fields at deep-subwavelength scale, leading to many applications such as super-resolution imaging [3], plasmonic lasers [4], surfaced-enhanced Raman effect [5], plasmonic waveguides [6,7] or circuits [8], etc. In practice, scatterings of SPPs to propagating waves (PWs) are inevitable as SPPs encounter discontinuities (say, interfaces between two different plasmonic systems). Such scatterings can lead to undesired radiation losses which should be avoided, especially in those applications employing SPPs as information carriers (say, plasmonic waveguides and nano-circuits [6–8]). Meanwhile, SPP-PW scatterings can also be utilized to achieve certain desired functionalities. For example, one can purposely place a set of carefully designed scatters on a plasmonic surface to scatter SPPs, generating fascinating effects such as holograms, focusing, or even directional radiations [9,10]. However, theoretical understandings on the inherent physics governing SPP-PW scatterings are far from satisfactory. Without a simple picture on such processes, people usually have to rely on full-wave simulations to optimize the devices to either suppress or utilize the SPP-PW scatterings. Although several theoretical approaches were proposed to study the SPP transmission/ reflection behaviors at certain plasmonic interfaces [11,12], the SPP-PW scatterings are usually overlooked. Moreover, since PWs have infinite channels to transport in free space, it is difficult to derive an analytical formula to describe such SPP-PW processes. | Fuxin Guan Shulin Sun Shiyi Xiao Qiong He Lei Zhou | 2019 | Science Bulletin2019，64，12： | 4 |
| 5 | Enhancement of oxygen reduction reaction activity by grain boundaries in platinum nanostructures显示文摘Systematic control of grain boundary densities in various platinum(Pt)nanostructures was achieved by specific peptide-assisted assembly and coagulation of nanocrystals.A positive quadratic correlation was observed between the oxygen reduction reaction(ORR)specific activities of the Pt nanostructures and the grain boundary densities on their surfaces.Compared to commercial Pt/C,the grain-boundary-rich strain-free Pt ultrathin nanoplates demonstrated a 15.5 times higher specific activity and a 13.7 times higher mass activity.Simulation studies suggested that the specific activity of ORR was proportional to the resident number and the resident time of oxygen on the catalyst surface,both of which correlate positively with grain boundary density,leading to improved ORR activities. | Enbo Zhu Wang Xue Shiyi Wang Xucheng Yan Jingxuan Zhou Yang Liu Jin Cai Ershuai Liu Qingying Jia Xiangfeng Duan Yujing Li Hendrik Heinz Yu Huang | 2020 | Nano Research2020，13，12： | 3 |
| 6 | Progress and prospects of carbon dioxide capture,EOR-utilization and storage industrialization显示文摘Carbon dioxide capture,EOR-utilization and storage(CCUS-EOR)are the most practical and feasible large-scale carbon reduction technologies,and also the key technologies to greatly improve the recovery of low-permeability oil fields.This paper sorts out the main course of CCUS-EOR technological development abroad and its industrialization progress.The progress of CCUS-EOR technological research and field tests in China are summarized,the development status,problems and challenges of the entire industry chain of CO_(2) capture,transportation,oil displacement,and storage are analyzed.The results show a huge potential of the large-scale application of CCUS-EOR in China in terms of carbon emission reduction and oil production increase.At present,CCUS-EOR in China is in a critical stage of development,from field pilot tests to industrialization.Aiming at the feature of continental sedimentary oil and gas reservoirs in China,and giving full play to the advantages of the abundant reserves for CO_(2) flooding,huge underground storage space,surface infrastructure,and wide distribution of wellbore injection channels,by cooperating with carbon emission enterprises,critical technological research and demonstration project construction should be accelerated,including the capture of low-concentration CO_(2) at low-cost and on large-scale,supercritical CO_(2) long-distance transportation,greatly enhancing oil recovery and storage rate,and CO_(2) large-scale and safe storage.CCUS-EOR theoretical and technical standard system should be constructed for the whole industrial chain to support and promote the industrial scale application,leading the rapid and profitable development of CCUS-EOR emerging industrial chain with innovation. | YUAN Shiyi MA Desheng LI Junshi ZHOU Tiyao JI Zemin HAN Haishui | 2022 | Petroleum Exploration and Development2022，49，4： | 2 |
| 7 | Tailoring the lineshapes of coupled plasmonic systems based on a theory derived from first principles显示文摘Coupled photonic systems exhibit intriguing optical responses attracting intensive attention,but available theoretical tools either cannot reveal the underlying physics or are empirical in nature.Here,we derive a rigorous theoretical framework from first principles(i.e.,Maxwell’s equations),with all parameters directly computable via wave function integrations,to study coupled photonic systems containing multiple resonators.Benchmark calculations against Mie theory reveal the physical meanings of the parameters defined in our theory and their mutual relations.After testing our theory numerically and experimentally on a realistic plasmonic system,we show how to utilize it to freely tailor the lineshape of a coupled system,involving two plasmonic resonators exhibiting arbitrary radiative losses,particularly how to create a completely“dark”mode with vanishing radiative loss(e.g.,a bound state in continuum).All theoretical predictions are quantitatively verified by our experiments at near-infrared frequencies.Our results not only help understand the profound physics in such coupled photonic systems,but also offer a powerful tool for fast designing functional devices to meet diversified application requests. | Jing Lin Meng Qiu Xiyue Zhang Huijie Guo Qingnan Cai Shiyi Xiao Qiong He Lei Zhou | 2020 | Light(Science & Applications)2020，9，1： | 2 |
| 8 | TaASR1 , a transcription factor gene in wheat, confers drought stress tolerance in transgenic tobacco显示文摘 | WEI HU CHAO HUANG XIAOMIN DENG SHIYI ZHOU LIHONG CHEN YIN LI CHENG WANG ZHANBING MA QIANQIAN YUAN YAN WANG RUI CAI XIAOYU LIANG GUANGXIAO YANG GUANGYUAN HE | 2013 | Plant Cell Environ2013，，8： | 1 |
| 9 | Research on Causality Relationship of Low-Carbon Development and Industrial Structure显示文摘 | Liu Chunmei Duan Maosheng Zhang Xiliang Zhou Jieting Zhang Tianhou Yang Guang Ou Xunmin Wang Enchuang Dai Chunyan Guo Shiyi Hu Guangping Zhou Lingling Qi Tianyu | 2011 | Procedia Environmental Sciences2011，，： | 1 |
| 10 | WALK-ASSISTING BALANCE SYSTEM OF THE EXOSKELETON ROBOT FOR DISABLED PEOPLE显示文摘A novel methodology for a walk-assisting balance system of the exoskeleton robot for disabled people is presented.The experiment on the walk-assisting balance system is implemented using a mini-type ropewalker robot.The mechanism of the ropewalker robot is designed,its dynamic model is built,and its control system based on PWM is developed.The emulations in Matlab and the results of experiments prove that this methodology is effective. | Yin Yuehong Zhou Chunlin Song Jiaren Chen Shiyi Han Tianpu Zhou Chen Research Institute of Robotics,Shanghai Jiaotong University,Shanghai 200030, China | 2004 | Chinese Journal of Mechanical Engineering2004，17，2： | 1 |
| 11 | Morphology and properties of injection molded microcellular poly(ether imide)(PEI)/polypropylene(PP) foams显示文摘 | Tao Liu Shiyi Zhou Yajie Lei | 2014 | Ind Eng Chem Res2014，53，11： | 1 |
| 12 | Low Envi- ronmental Sensitive Antistatic Material Based on Poly (Vinyl Chloride)/Quaternary Ammonium Salt by Blend- ing with Poly ( Ethylene Oxide) 显示文摘 | Kuang Minxuan Zhou Shiyi Lei Jingxin | 2008 | Journal of Applied Polymer Science2008，109，： | 1 |
| 13 | Advances in“design by analysis” methods for pressure vessels 显示文摘 | Zhou Yu Bao Shiyi Dong Jianling | 2006 | Journal of Tsinghua University2006，46，6： | 1 |
| 14 | Overexpression of the wheat aquaporin gene,TaAQP7,enhances drought tolerance in transgenic tobacco显示文摘 | Shiyi Zhou Wei Hu Xiaomin Deng | 2012 | PLoS One2012，7，12： | 1 |
| 15 | Engineering single-molecule fluorescence withasymmetric nano-antennas显示文摘As a powerful tool for studying molecular dynamics in bioscience,single-molecule fluorescence detection providesdynamical information buried in ensemble experiments.Fluorescence in the near-infrared(NIR)is particularly usefulbecause it offers higher signal-to-noise ratio and increased penetration depth in tissue compared with visiblefluorescence.The low quantum yield of most NIR fluorophores,however,makes the detection of single-moleculefluorescence difcult.Here,we use asymmetric plasmonic nano-antenna to enhance the fluorescence intensity ofAlEE1000,a typical NIR dye,by a factor up to 405.The asymmetric nano-antenna achieve such an enhancement mainlyby increasing the quantum yield(to~80%)rather than the local field,which degrades the molecules'photostability.Our coupled-mode-theory analysis reveals that the enhancements stem from resonance-matching between antennaand molecule and,more importantly,from optimizing the coupling between the near-and far-ield modes withdesigner asymmetric structures.Our work provides a universal scheme for engineering single-molecule fluorescence inthe near-infrared regime. | Wenqi Zhao Xiaochaoran Tian Zhening Fang Shiyi Xiao Meng Qiu Qiong He Wei Feng Fuyou Li Yuanbo Zhang Lei Zhou Yan-Wen Tan | 2021 | Light(Science & Applications)2021，10，5： | 1 |
| 16 | Creation of radially polarized optical fields with multiple controllable parameters using a vectorial optical field generator显示文摘A vectorial optical field generator(VOF-Gen) based on two reflective phase-only liquid crystal spatial light modulators enables the creation of an arbitrary optical complex field. In this work, the capabilities of the VOF-Gen in terms of manipulating the spatial distributions of phase, amplitude, and polarization are experimentally demonstrated by generating a radially polarized optical field consisted of five annular rings, the focusing properties of which are also numerically studied with vectorial diffraction theory. By carefully adjusting the relative amplitude and phase between the adjacent rings, an optical needle field with purely longitudinal polarization can be produced in the focal region of a high numerical aperture lens. The versatile method presented in this work can be easily extended to the generation of a vectorial optical field with any desired complex distributions. | Sichao Zhou Shiyi Wang Jian Chen Guanghao Rui Qiwen Zhan | 2016 | Photonics Research2016，4，5： | 1 |
| 17 | Synthesis of 3D printing materials and their electrochemical applications显示文摘Three-dimensional(3 D)printing,also known as additive manufacturing,has the advantages of low cost,easy structure operation,rapid prototyping,and easy customization.In the past few years,materials with different structures,compositions,and properties have been widely studied as prospects in the field of 3 D printing.This paper reviews the synthesis methods and morphologies of one-,two-and threedimensional micro/nano materials and their composites,as well as their applications in electrochemistry,such as supercapacitors,batteries and electrocatalysis.The latest progress and breakthroughs in the synthesis and application of different structural materials in 3 D-printing materials,as well as the challenges and prospects of electrochemical applications,are discussed. | Huijie Zhou Hui Yang Shiyi Yao Li Jiang Nuochen Sun Huan Pang | 2022 | Chinese Chemical Letters2022，33，8： | 1 |
| 18 | Degradation strategies of pesticide residue:From chemicals tosynthetic biology显示文摘The past 50 years have witnessed a massive expansion in the demand and application of pesticides.However,pesticides are difficult to be completely degraded without intervention hence the pesticide residue could pose a persistent threat to non-target organisms in many aspects.To aim at the problem of the abuse of pesticide products and excessive pesticide residues in the environment,chemical and biological degradation methods are widely developed but are scaled and insufficient to solve such a pollution.In recent years,bio-degradative tools instructed by synthetic biological principles have been further studied and have paved a way for pesticide degradation.Combining the customized design strategy and standardized assembly mode,the engineering bacteria for multi-dimensional degradation has become an effective tool for pesticide residue degradation.This review introduces the mechanisms and hazards of different pesticides,summarizes the methods applied in the degradation of pesticide residues,and discusses the advantages,applications,and prospects of synthetic biology in degrading pesticide residues. | Bi Ruomeng Ou Meihao Zhou Siru Geng Shichen Zheng Yixian Chen Junhong Mo Ruijie Li Yuan Xiao Gezhi Chen Xingyu Zhai Shiyi Zhang Aihui Fang Baishan | 2023 | Synthetic and Systems Biotechnology2023，8，2： | 0 |
| 19 | A Pair of New Spirocyclic Alkaloid Enantiomers with TrxR Inhibitory Activities Were Isolated from Marine-Derived Aspergillus ruber TX-M4-1显示文摘One new spirocyclic alkaloid,5-isopentenyl-cryptoechinuline D(1),along with 11 known compounds(2–12),were iso-lated from a marine fungus Aspergillus ruber TX-M4-1.The structures of compounds 1–12 were elucidated by spectroscopic evi-dences.Compound 1 was initially isolated as an enantiomer,and further separation of 1 by chiral HPLC afforded a pair of enantio-mers,including(-)-5-isopentenyl-cryptoechinuline D(1a)and(+)-5-isopentenyl-cryptoechinuline D(1b).Their absolute configura-tions were elucidated by ECD spectroscopic data.Compounds 1a,5 and 10 could inhibit thioredoxin reductase(TrxR)activity with IC50 values of 6.2,36.3 and 18.6μmol L^(-1),respectively.Surface plasmon resonance(SPR)study also demonsrated the interactions between compounds 6,8 and Niemann-Pick C1 Like 1(NPC1L1)respectively,which indicate that compounds 6 and 8 are potential NPC1L1 inhibitors. | WANG Cong WANG Yufei SUN Jian WANG Shiyi DU Weisheng ZHOU Liman KONG Fandong | 2023 | Journal of Ocean University of China2023，22，6： | 0 |
| 20 | Dual cross-linked MXene/cellulose nanofiber/nickel alginate film with improved mechanical properties and electromagnetic interference shielding performance显示文摘Electromagnetic interference pollution has raised urgent demand for the development of electromagnetic interference shielding materials.Transition metal carbides(MXenes)with excellent conductivity have shown great potential in electromagnetic interference(EMI)shielding materials,while the poor mechanical strength,flexibility,and structural stability greatly limit their further applications.Here,cellulose nanofibers and sodium alginate are incorporated with MXene nanosheets as flexible matrices to construct strong and flexible mussellike layered MXene/Cellulose nanofiber/Sodium Alginate composite films,and nickel ions are further introduced to induce metal coordination crosslinking of alginate units.Benefited from the dual-crosslinked network structure of hydrogen bonding and metal coordination,the tensile strength,Young’s modulus,and toughness of the MXene/cellulose nanofiber/nickel alginate composite film are significantly increased.After subsequent reduction by ascorbic acid,excess nickel ions are reduced to nickel nanoparticles and uniformly dispersed within the highly conductive composite film,which further improved its hysteresis loss effect toward the incident electromagnetic waves.Consequently,the MXene/cellulose nanofiber/nickel alginate-Ni composite film presents a considerably enhanced electromagnetic interference shielding effectiveness(47.17 dB)at a very low thickness of 29μm.This study proposes a feasible dual-crosslinking and subsequent reduction strategy to synergistically enhance the mechanical properties and electromagnetic interference shielding performance of MXene-based composite materials. | Pengcheng Deng Shiyi Feng Canhui Lu Zehang Zhou | 2023 | Frontiers of Chemical Science and Engineering2023，17，10： | 0 |
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