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6篇 您的检索式:作者名="Tianwei Jing"
    题名 作者 年代 出处 被引量
1A "green pathway" different from simple diffusion in soft matter: Fast molecular transport within micro/nanoscale multiphase porous systems显示文摘Jiantao Feng Fang Wang Xinxiao Han Zhuo Ao Quanmei Sun Wenda Hua Peipei Chen Tianwei Jing Hongyi Li Dong Han 2014Nano Research2014,7,3:18
2Efficient production of chemicals from microorganism by metabolic engineering and synthetic biology显示文摘The use of traditional chemical catalysis to produce chemicals has a series of drawbacks,such as high dependence on fossil resources,high energy consumption,and environmental pollution.With the development of synthetic biology and metabolic engineering,the use of renewable biomass raw materials for chemicals synthesis by constructing efficient microbial cell factories is a green way to replace traditional chemical catalysis and traditional microbial fermentation.This review mainly summarizes several types of bulk chemicals and high value-added chemicals using metabolic engineering and synthetic biology strategies to achieve efficient microbial production.In addition,this review also summarizes several strategies for effectively regulating microbial cell metabolism.These strategies can achieve the coupling balance of material and energy by regulating intracellular material metabolism or energy metabolism,and promote the efficient production of target chemicals by microorganisms.Yang Zhang Jing Yu Yilu Wu Mingda Li Yuxuan Zhao Haowen Zhu Changjing Chen Meng Wang Biqiang Chen Tianwei Tan 2021Chinese Journal of Chemical Engineering2021,34,2:2
3Boosted activity by engineering the enzyme microenvironment in cascade reaction: A molecular understanding显示文摘Engineering of enzyme microenvironment can surprisingly boost the apparent activity.However,the underlying regulation mechanism is not well-studied at a molecular level so far.Here,we present a modulation of two model enzymes of cytochrome c(Cty C)and D-amino acid oxidase(DAAO)with opposite pH-activity profiles using ionic polymers.The operational pH of poly(acrylic acid)modified Cyt C and polyallylamine modified DAAO was extended to 3-7 and 2-10 where the enzyme activity was larger than that at their optimum pH of 4.5 and 8.5 by 106%and 28%,respectively.The cascade reaction catalyzed by two modified enzymes reveals a 1.37-fold enhancement in catalytic efficiency compared with their native counterparts.The enzyme activity boosting is understood by performing the UV-vis/CD spectroscopy and molecular dynamics simulations in the atomistic level.The increased activity is ascribed to the favorable microenvironment in support of preserving enzyme native structures nearby cofactor under external perturbations.Jing Wang Haiyang Zhang Deping Yin Xiao Xu Tianwei Tan Yongqin Lv 2021Synthetic and Systems Biotechnology2021,6,3:1
4Volitinib, a potent and highly selective c-Met inhibitor, effectively blocks c-Met signaling and growth in c-MET amplified gastric cancer patient-derived tumor xenograft models显示文摘Paul R. Gavine Yongxin Ren Lu Han Jing Lv Shiming Fan Wei Zhang Wen Xu Yuan Jie Liu Tianwei Zhang Haihua Fu Yongjuan Yu Huiying Wang Shirlian Xu Feng Zhou Xinying Su XiaoLu Yin Liang Xie Linfang Wang Weiguo Qing Longxian Jiao Weiguo Su Q. May Wang 2014Molecular Oncology2014,,:1
5A magnetically driven oscillating probe microscope for operation in liquids显示文摘Han W Lindsay S Jing Tianwei 1996Appl Phys Lett1996,69,26:1
6Chiral CdSe/CdS quantum dot (in rod)-light-emitting diodes with circularly polarized electroluminescence显示文摘Chiral quantum dot(in rod)-light-emitting diodes(CQLEDs)with circularly polarized electroluminescence(CPEL)have driven interest in the future display,communication,and storage industries.However,the preparation of CQLEDs is still a challenging unresolved.Herein,we fabricated CQLEDs through spin-coating evaporation of chiral CdSe/CdS quantum rods(CCCQs)colloidal solution on indium tin oxide substrate.The CCCQs were synthesized via an isotropically epitaxial growth with cholic acid as the symmetry breaking agent,which induced one-direction chiral dislocation around the c axis of their hexagonal crystal structure.The CCCQs were ranked side-by-side in right-handed chiral arrangement with helical axis perpendicular to substrate due to chiral driving force of the cholic acid arrangement.The CQLEDs exhibited a negative CPEL signal at 600 nm with a|gEL|of 2×10^(−4),which is ascribable to the selective filtration on emission arising from the circular Bragg resonance by quasi-photonic crystal structures.Tianwei Duan Jing Ai Sujie Chen Gufeng He Xiaojun Guo Lu Han Shunai Che Yingying Duan 2022Nano Research2022,15,10:0
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