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| 1 | Micro-light-emitting diodes with quantum dots in display technology显示文摘Micro-light-emitting diodes(μ-LEDs)are regarded as the cornerstone of next-generation display technology to meet the personalised demands of advanced applications,such as mobile phones,wearable watches,virtual/augmented reality,micro-projectors and ultrahigh-definition TVs.However,as the LED chip size shrinks to below 20μm,conventional phosphor colour conversion cannot present sufficient luminance and yield to support highresolution displays due to the low absorption cross-section.The emergence of quantum dot(QD)materials is expected to fill this gap due to their remarkable photoluminescence,narrow bandwidth emission,colour tuneability,high quantum yield and nanoscale size,providing a powerful full-colour solution for μ-LED displays.Here,we comprehensively review the latest progress concerning the implementation of μ-LEDs and QDs in display technology,including μ-LED design and fabrication,large-scale μ-LED transfer and QD full-colour strategy.Outlooks on QD stability,patterning and deposition and challenges of μ-LED displays are also provided.Finally,we discuss the advanced applications of QD-based μ-LED displays,showing the bright future of this technology. | Zhaojun Liu Chun-Ho Lin Byung-Ryool Hyun Chin-Wei Sher Zhijian Lv Bingqing Luo Fulong Jiang Tom Wu Chih-Hsiang Ho Hao-Chung Kuo Jr-Hau He | 2020 | Light(Science & Applications)2020，9，1： | 12 |
| 2 | FORCE RIPPLE SUPPRESSION TECHNOLOGY FOR LINEAR MOTORS BASED ON BACK PROPAGATION NEURAL NETWORK显示文摘Various force disturbances influence the thrust force of linear motors when a linear motor (LM) is running.Among all of force disturbances,the force ripple is the dominant while a linear motor runs in low speed.In order to suppress the force ripple,back propagation(BP) neural network is proposed to learn the function of the force ripple of linear motors,and the acquisition method of training samples is proposed based on a disturbance observer.An off-line BP neural network is used mainly because of its high running efficiency and the real-time requirement of the servo control system of a linear motor.By using the function,the force ripple is on-line compensated according to the position of the LM.The experimental results show that the force ripple is effectively suppressed by the compensation of the BP neural network. | ZHANG Dailin CHEN Youping AI Wu ZHOU Zude KONG Ching Tom | 2008 | Chinese Journal of Mechanical Engineering2008，21，2： | 7 |
| 3 | Role of nitric oxide in the genotoxic response to chronic microcystin-LR exposure in human–hamster hybrid cells显示文摘Microcystin-LR(MC-LR) is the most abundant and toxic microcystin congener and has been classified as a potential human carcinogen(Group 2B) by the International Agency for Research on Cancer. However, the mechanisms underlying the genotoxic effects of MC-LR during chronic exposure are still poorly understood. In the present study, human–hamster hybrid(AL) cells were exposed to MC-LR for varying lengths of time to investigate the role of nitrogen radicals in MC-LR-induced genotoxicity. The mutagenic potential at the CD59 locus was more than 2-fold higher(p < 0.01) in ALcells exposed to a cytotoxic concentration(1 μmol/L) of MC-LR for 30 days than in untreated control cells, which was consistent with the formation of micronucleus. MC-LR caused a dose-dependent increase in nitric oxide(NO) production in treated cells. Moreover, this was blocked by concurrent treatment with the NO synthase inhibitor NG-methyl-L-arginine(L-NMMA), which suppressed MC-LRinduced mutations as well. The survival of mitochondrial DNA-depleted(ρ0) ALcells was markedly decreased by MC-LR treatment compared to that in ALcells, while the CD59 mutant fraction was unaltered. These results provided clear evidence that the genotoxicity associated with chronic MC-LR exposure in mammalian cells was mediated by NO and might be considered as a basis for the development of therapeutics that prevent carcinogenesis. | Xiaofei Wang Pei Huang Yun Liu Hua Du Xinan Wang Meimei Wang Yichen Wang Tom K.Hei Lijun Wu An Xu | 2015 | Journal of Environmental Sciences2015，27，3： | 6 |
| 4 | Whole-genome sequencing to detect mutations associated with resistance to insecticides and Bt proteins in Spodoptera frugiperda显示文摘The fall armyworm(FAW),Spodoptera frugiperda,is a major pest native to the Americas that has recently invaded the Old World.Point mutations in the target-site proteins acetylcholinesterase-1(ace-1),voltage-gated sodium channel(VGSC)and ryanodine receptor(RyR)have been identified in S.frugiperda as major resistance mechanisms to organophosphate,pyrethroid and diamide insecticides respectively.Mutations in the adenosine triphosphate-binding cassette transporter C2 gene(ABCC2)have also been identified to confer resistance to Cry IF protein.In this study,we applied a whole-genome sequencing(WGS)approach to identify point mutations in the target-site genes in 150 FAW individuals collected from China,Malawi,Uganda and Brazil.This approach revealed three amino acid substitutions(A201S,G227A and F290V)of S.frugiperda ace-1,which are known to be associated with organophosphate resistance.The Brazilian population had all three ace-1 point mutations and the 227A allele(mean frequency=0.54)was the most common.Populations from China,Malawi and Uganda harbored two of the three ace-1 point mutations(A201S and F290V)with the 290V allele(0.47-0.58)as the dominant allele.Point mutations in VGSC(T929I,L932F and L1014F)and RyR(I4790M and G4946E)were not detected in any of the 150 individuals.A novel 12-bp insertion mutation in exon 15 of the ABCC2 gene was identified in some of the Brazilian individuals but absent in the invasive populations.Our results not only demonstrate robustness of the WGS-based genomic approach for detection of resistance mutations,but also provide insights for improvement of resistance management tactics in S.frugiperda. | Fang Guan Jianpeng Zhang Huiwen Shen Xingliang Wang Amanda Padovan Tom K.Walsh Wee Tek Tay Karl H.J.Gordon William James Cecilia Czepak Michael Hilary Otim Donald Kachigamba Yidong Wu | 2021 | Insect Science2021，28，3： | 6 |
| 5 | Deformation of the Zhangjiazhuang high-speed railway tunnel: an analysis of causal mechanisms using geomorphological surveys and D-InSAR monitoring显示文摘On 18 January 2016,the Zhangjiazhuang high-speed railway tunnel in Ledu,Qinghai Province,China,underwent serious deformation and structural damage.A crack formed at the top of the tunnel and the concrete on the crown peeled off.As a result,the tunnel could not be operated for three months.In order to determine the types and spatial distribution of the landslides in the region and the surface deformation characteristics associated with the tunnel deformation,we used field geological and geomorphological surveys,unmanned aerial vehicle image interpretation and differential interferometric synthetic aperture radar(D-In SAR) surface deformation monitoring.Nine ancient and old landslides were identified and analysed in the study area.Surface deformation monitoring and investigation of buildings in several villages on the slope front showed that the tunnel deformation was not related to deep-seated gravitational slope deformation.However,surface deformation monitoring revealed an active NEE–SWW fault in the area intersecting the tunnel at the location of the tunnel rupture.This constitutes a plausible mechanism for the deformation of the tunnel.Our study highlights the need for detailed engineering geomorphological investigations to better predict the occurrence of tunnel deformation events in the future. | MENG Xing-min QI Tian-jun ZHAO Yan DIJKSTRA Tom SHI Wei LUO Yin-fei WU Yuan-zhao SU Xiao-jun ZHAO Fu-meng MA Jin-hui ZHANG Yi CHEN Guan YUE Dong-xia ZHANG Mao-sheng | 2021 | Journal of Mountain Science2021，18，7： | 5 |
| 6 | Epidemiology of Alzheimer’s disease and other forms of dementia in China, 1990–2010: a systematic review and analysis显示文摘 | Kit Yee Chan Wei Wang Jing Jing Wu Li Liu Evropi Theodoratou Josip Car Lefkos Middleton Tom C Russ Ian J Deary Harry Campbell Wei Wang Igor Rudan | 2013 | The Lancet . 2013 (9882)2013，，9882： | 5 |
| 7 | Graphitic‐shell encapsulated FeNi alloy/nitride nanocrystals on biomass‐derived N‐doped carbon as an efficient electrocatalyst for rechargeable Zn‐air battery显示文摘Oxygen reduction/evolution reactions(ORR/OERs)catalysts play a key role in the metal‐air battery and water‐splitting process.Herein,we developed a facile template‐free method to fabricate a new type of non–noble metal‐based hybrid catalyst which consists of binary FeNi alloy/nitride nanocrystals with graphitic‐shell and biomass‐derived N‐doped carbon(NC)(FexNiyN@C/NC).This novel nanostructure exhibits superior performance for ORR/OER,which can be attributed to the strong interactions between the graphitic‐shell encapsulated FeNi alloy/nitride nanocrystals and the N‐doped porous carbon substrate.The X‐ray absorption spectroscopy technique was employed to reveal the underlying mechanisms for the excellent performance.The assembled Zn‐air battery device exhibits outstanding charging/discharging performance and cycling stability,indicating the great potential of this type of novel catalysts. | Mingjie Wu Gaixia Zhang Yongfeng Hu Jian Wang Tianxiao Sun Tom Regier Jinli Qiao Shuhui Sun | 2021 | Carbon Energy2021，3，1： | 4 |
| 8 | The complete reference genome for grapevine (Vitis vinifera L.) genetics and breeding显示文摘Grapevine is one of the most economically important crops worldwide.However,the previous versions of the grapevine reference genome tipically consist of thousands of fragments with missing centromeres and telomeres,limiting the accessibility of the repetitive sequences,the centromeric and telomeric regions,and the study of inheritance of important agronomic traits in these regions.Here,we assembled a telomere-to-telomere(T2T)gap-free reference genome for the cultivar PN40024 using PacBio HiFi long reads.The T2T reference genome(PN_T2T)is 69 Mb longer with 9018 more genes identified than the 12X.v0 version.We annotated 67%repetitive sequences,19 centromeres and 36 telomeres,and incorporated gene annotations of previous versions into the PN_T2T assembly.We detected a total of 377 gene clusters,which showed associations with complex traits,such as aroma and disease resistance.Even though PN40024 derives from nine generations of selfing,we still found nine genomic hotspots of heterozygous sites associated with biological processes,such as the oxidation–reduction process and protein phosphorylation.The fully annotated complete reference genome therefore constitutes an important resource for grapevine genetic studies and breeding programs. | Xiaoya Shi Shuo Cao Xu Wang Siyang Huang Yue Wang Zhongjie Liu Wenwen Liu Xiangpeng Leng Yanling Peng Nan Wang Yiwen Wang Zhiyao Ma Xiaodong Xu Fan Zhang Hui Xue Haixia Zhong Yi Wang Kekun Zhang Amandine Velt Komlan Avia Daniela Holtgräwe Jérôme Grimplet JoséTomás Matus Doreen Ware Xinyu Wu Haibo Wang Chonghuai Liu Yuling Fang Camille Rustenholz Zongming Cheng Hua Xiao Yongfeng Zhou | 2023 | Horticulture Research2023，10，5： | 3 |
| 9 | Phase segregation in inorganic mixed-halide perovskites:from phenomena to mechanisms显示文摘Halide perovskites,such as methylammonium lead halide perovskites(MAPbX3,X=I,Br,and Cl),are emerging as promising candidates for a wide range of optoelectronic applications,including solar cells,light-emitting diodes,and photodetectors,due to their superior optoelectronic properties.All-inorganic lead halide perovskites CsPbX3 are attracting a lot of attention because replacing the organic cations with Cs+enhances the stability,and its halide-mixing derivatives offer broad bandgap tunability covering nearly the entire visible spectrum.However,there is evidence suggesting that the optical properties of mixed-halide perovskites are influenced by phase segregation under external stimuli,especially illumination,which may negatively impact the performance of optoelectronic devices.It is reported that the mixed-halide perovskites in forms of thin films and nanocrystals are segregated into a low-bandgap I-rich phase and a high-bandgap Br-rich phase.Herein,we present a critical review on the synthesis and basic properties of all-inorganic perovskites,phase-segregation phenomena,plausible mechanisms,and methods to mitigate phase segregation,providing insights on advancing mixed-halide perovskite optoelectronics with reliable performance. | Yutao Wang Xavier Quintana Jiyun Kim Xinwei Guan Long Hu Chun-Ho Lin Brendon Tyler Jones Weijian Chen Xiaoming Wen Hanwei Gao Tom Wu | 2020 | Photonics Research2020，8，11： | 3 |
| 10 | Penile prosthesis implantation in Chinese patients wit severe erectile dysfunction: 10-year experience显示文摘我们回顾地与严重可勃起的机能障碍(SED ) 在中国病人评估了阴茎修复术培植(PPI ) 的临床的结果。从 2000 年 7 月到 2011 年 12 月, 224 个病人(吝啬的年龄:35.9 ± 11.8 年,变化:20-75 年) 在我们的中心根据标准 PPI 过程由富有经验的外科医生与 SED 经历了 PPI。韧性的修复术(AMS 650 ) 在 45 种情况中被植入(20.1 %) ,并且三片的可膨胀的修复术(AMS 700 CXM 或 AMS 700 CXR ) 在 179 种情况中被植入(79.9 %) 。包括手术后的复杂并发症,临床的功效和夫妇满足,外科的结果被评估在上比手术后地使用医药记录抽象的 6 个月, IIEF-5,生活(QoL ) 的质量分数,和病人 / 搭挡的性满足分数由 Bhojwani 等求婚了。为学习合格的 224 个病人, 201 使遭到(89.7 %) 完成的后续。所有能与吝啬的手术后的 IIEF-5 病人执行性交柱子 PPI, QoL 分数是 20.02 ± 2.32 和 5.28 ± 0.76,分别地它显著地与外科手术前的分数相比被改进(6.29 ± 1.5 和 2.13 ± 0.84, P< 0.01 ) 。201 个人,机械失灵发生在四种情况中(2.0 %) 并且三个盒子被重新植入新设备,和二个盒子(1.0 %) 开发了阴茎的温和弯曲。有感染的阴囊的侵蚀与糖尿病 mellitus 发生在一种情况中(0.5 %) 并且植入的 AMS 的要求的完全的移动 700 CXM。令人满意的性交被 178 个人两次至少每月报导(88.6 %) ,并且对 PPI 外科的全面满足被 89.0 % 报导;人和 82.5 %搭挡。在三片的可膨胀的修复术组的耐心的满足比在韧性的修复术组高(P< 0.05 ) 。然而,在 prostheses 的类型之间,满足没在搭挡调查不同。PPI 是一种安全、有效的治疗选择因为有 SED 和富有经验的外科医生的中国病人根据标准 PPI 执行 PPI 过程能减少 PPI 的手术后的复杂并发症并且能改进耐心的满足比率和 QoL。 | Wei-Dong Song Yi-Ming Yuan Wan-Shou Cui Alex K Wu Yi-Chen Zhu Jing Liu Lin Wang Guang-Yi Ba Jing Peng Zhi-Chao Zhang Bing Gao Ying-Lu Guo Tom F Lue Zhong-Cheng Xin | 2013 | Asian Journal of Andrology2013，15，5： | 3 |
| 11 | Tunica albuginea allograft: a new model of LaPeyronie's disease with penile curvature and subtunical ossification显示文摘LaPeyronie 的疾病(PD ) 的 pathophysiology 被认为是 multifactorial,包含愈合的基因倾向,损伤,发炎和改变的创伤。然而,这些因素还没用动物模型被验证了。在这研究,我们介绍了 tunica albuginea allograft 获得的一个新模型。40 的一个总数, 16-week-old 男性老鼠被使用。这些, 8 只老鼠用作控制并且经历了 10 ×有随后的 autografting 的 2-mm-wide tunical 切除,而留下 32 与另一只老鼠的 tunica 与缺点的 grafting 经历了一样的切除。词法、功能测试在 grafting 以后在 1, 3, 7 和 12 个星期被执行。Intracavernous 压力,阴茎弯曲的度和有弹性的纤维长度为在 allograft 和控制组之间的比较被评估。纸巾为组织学的检查被获得。阴茎弯曲作为与控制老鼠相比在 allografted 老鼠是显著地更大的。可勃起的功能在所有老鼠被维持,除了在在 12 个星期估计的那些。弹力素纤维长度作为与控制相比在 allografted tunica 被减少。SMAD2 表示在 allograft 的内部部分被检测,并且 collagen-II- 和 osteocalcin 积极的房间也被注意。在老鼠的 Tunica albuginea (TA ) allograft 是 PD 的一个优秀模型。在 12 个星期和在 TA 的内部层的骨化的存在以后的弯曲的坚持类似于与 PD 在人观察的那些。用这个动物模型的确认研究将为有效治疗学的干预帮助 PD pathophysiology 的理解。 | Ludovic Ferretti Thomas M Fandel Xuefeng Qiu Haiyang Zhang Hazem Orabi Alex K Wu Lia Banie Guifang Wang Guiting Lin Ching-Shwun Lin Tom FLue | 2014 | Asian Journal of Andrology2014，16，4： | 3 |
| 12 | Development of an antibody that neutralizes soluble IgE and eliminates IgE expressing B cells显示文摘免疫球蛋白 E (IgE ) 在过敏气喘起一个关键作用并且是为 monoclonal 抗体的一个临床上验证的目标。治疗学的 anti-IgE 抗体块在 IgE 和 Fc epsilon 之间的相互作用(Fcε) 受体,它消除或最小化,但是做过敏显型不典型地由 B 房间削减 IgE 的进行中的生产。我们产生了有潜力抵销可溶的 IgE 并且通过抗体依赖者消除表示 IgE B 房间的高亲密关系的 anti-IgE 抗体(MEDI4212 ) 调停房间的 cytotoxicity。MEDI4212 变体被产生在 fucosylation 在抗体或改变的 Fc 区域包含变化以便为 Fcγ 提高抗体亲密关系; RIIIa。所有 MEDI4212 变体与比得上的亲密关系跳了到人的 IgE 野类型(WT ) 抗体。每变体被显示禁止在 IgE 和 Fcε 之间的相互作用; RI,它翻译了成 Fcγ 的有势力抑制;调停 RI 的功能回答。重要地,所有变体在表示房间的膜 IgE 的表面同样跳了到 IgE。然而, MEDI4212 变体为 Fcγ 表明了提高的亲密关系;包括在位置 158 点的多态的变体的 RIIIa。在 Fcγ 的改进;导致的 RIIIa 绑定在用两个都设计的房间线和类的基于的试金交换了的房间增加了受动器功能人的 IgE B 房间。通过它 IgE 的优异抑制,我们预计那受动器功能提高了 MEDI4212 也许能抵销可溶的 IgE 的高水平并且在他们区分并且变得 IgE secreting 血浆房间以前,由消除表示 B 房间的 IgE 提供增加的长期的利益。 | Andrew C. Nyborg Anna Zacco Rachel Ettinger M. Jack Borrok Jie Zhu Tom Martini Rob Woods Christine Kiefer Michael A. Bowen E. Suzanne Cohenz Ronald Herbst Herren Wu Steven Coats | 2016 | Cellular & Molecular Immunology2016，13，3： | 3 |
| 13 | Comparative experiments and effectiveness evaluation on vertical blowing fans(VBF)for frost protection显示文摘Experiments were conducted to evaluate the performance of vertical blowing fans(VBF)for frost protection in a vineyard on a steep slope near Napa Valley in Northern California,USA,and a tea plantation located on undulating terrain in Zhenjiang,China.Minimum temperature comparisons from within the grape vineyard on nights with and without VBF operation with control station minimum temperatures exhibited no temperature benefit.Profile measurements from the test in China indicated that there was an increase in temperature when the VBF was first started,but that benefit was lost over time.No clear benefit from using the VBF was observed.Observation of frost deposition and thermal imagery also showed no benefit except for within about 5 m of the VBF.Based on this work,the effectiveness of the VBF for frost protection was not validated. | Hu Yongguang Wu Wenye J.Paulo De Melo-Abreu Tom M.Shapland Zhang Hong Richard L.Snyder | 2015 | International Journal of Agricultural and Biological Engineering2015，8，5： | 2 |
| 14 | Columbia University microbeam: development of anexperimental system for targeting cells individually withcounted particles显示文摘Columbia University microbeam was constructed in 1993 and finished by the end of 1995. It is well established and used routinely to irradiate cells in a highly localized spatial region with a defined number of α-particles. By using this probe, it is possible to study a number of radiobiological questions in ways that cannot be simulated by using conventional broad-field exposures. This report describes the development and current capabilities of the Columbia University microbeam, as well as the preliminary researches undertaken. | WU Lijun Tom K. HEI Gerhard RANDER-PEHRSON WANG Shaohu YU Zengliang (1Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230051, China 2Center for Radiological Research, Columbia University, New York 10032, USA) | 1999 | Nuclear Science and Techniques1999，10，3： | 2 |
| 15 | Platelet thrombus formation on collagen at high shear rates is mediated by von Willebrand factor glycoprotein Ib interaction and inhibited by yon Willebrand factor-glycoprotein Ⅱ b/Ⅲ a interaction显示文摘 | Wu YP Tom Vink Marion Schiphorst | 2000 | Arterioscler Thromb Vasc Biol2000，20，6： | 1 |
| 16 | Targeted cytoplasmic irradiation with alpha particles induces mutations in mammalian cells显示文摘 | Wu L J Zhou H N Tom K H | 1999 | Proc Natl Acad Sci USA1999，96，： | 1 |
| 17 | Proximal vascular pedicle preservation for sartorius muscle flap transposition显示文摘 | Wu Liza C Djohan Risal S Liu Tom S | | 0，，01： | 1 |
| 18 | Polymer Nanofiber‐Embedded Microchips for Detection, Isolation, and Molecular Analysis of Single Circulating Melanoma Cells显示文摘 | Shuang Hou Libo Zhao Qinglin Shen Juehua Yu Charles Ng Xiangju Kong Dongxia Wu Min Song Xiaohong Shi Xiaochun Xu Wei‐Han OuYang Rongxian He Xing‐Zhong Zhao Tom Lee F. Charles Brunicardi Mitch André Garcia Antoni Ribas Roger S. Lo Hsian‐Rong Tseng | 2013 | Angew Chem Int Ed2013，，12： | 1 |
| 19 | Mutagenic effects of a single and an exact number of alpha particles in mammalian cells 显示文摘 | Tom K Hei Wu L J Liu S X | 1997 | Proc Natl Acad Sci USA1997，94，： | 1 |
| 20 | Epidemiology of Alzheimer’s disease and other forms of dementia in China, 1990–2010: a systematic review and analysis显示文摘 | Kit Yee Chan Wei Wang Jing Jing Wu Li Liu Evropi Theodoratou Josip Car Lefkos Middleton Tom C Russ Ian J Deary Harry Campbell Wei Wang Igor Rudan | 2013 | The Lancet2013，，9882： | 1 |
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