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| 1 | Expression of IL-10 and TNF-α in Rats with Cerebral Infarction after Transplantation with Mesenchymal Stem Cells显示文摘我们调查了骨头的效果在老鼠的 MCAO (中间的服的动脉吸藏) 的神经病学的功能的恢复上的导出髓的间充质的干细胞(MSC ) 移植模型和它的 mechanism.MSCs 从男 Sprague Dawley (SD ) 老鼠的骨头髓被孤立。女成年 SD 老鼠随机被分配进 4 个组:假冒操作组, MCAO 组,车辆组和 MCAO +对待 MSCs 的组。MSC 在对待 MSCs 的组被注入老鼠的侧面的室, PBS 的一样的体积被给车辆组。IL-10 和 TNF- 的表情在 MCAO 以后是由在白天 1 和 4 点的 RT-PCR 和 ELISA 察觉的 assayed。梗塞体积被染色 TTC 测量。老鼠经历了的所有行为的测试在前,以及在 MCAO 以后的 1, 4,和 14 天。MSC 显著地在在移植以后的白天 14 点与控制相比改进了功能的恢复。与 MCAO 组和车辆相比,组, IL-10 mRNA 的表示和它的蛋白质显著地在 MSC 组铺平 upregulated。然而, TNF 的表示 -- 4 显著地在在 MSC 的 MCAO 以后组织的一 at 天与 MCAO 组和车辆组的相比减少了。作为结果,有 MSC 的移植显著地减少了在白天 1 和 4 点的梗塞体积。这研究强烈建议有 MSC 的移植能减少 neuronal 损害由在大脑调整 IL-10 和 TNF- 的表达式部分在老鼠张贴焦点的服的局部缺血。细胞与分子的免疫学。2009; 6 (3 ): 207-213。 | Nan Liu Ronghua Chen Houwei Du Jiehua Wang Yixian Zhang Jinsen Wen | 2009 | Cellular & Molecular Immunology2009，6，3： | 40 |
| 2 | Adakite-type sodium-rich rocks in Awulale Mountain of west Tianshan:Significance for the vertical growth of continental crust显示文摘The sodium-rich dacites and albite porphyries of Permian in the Awulale Mountain of west Tianshan have unique chemical and trace element signatures identical to adakite. These intermediate-acidic igneous rocks are characterized by high Na2O, Al2O3 and Sr contents and high Sr/Y and La/Y ratios (>40 and >20, respectively), and low Y and Yb contents, and strong depletion in HREE, and positive Eu anomaly. The (143Nd/144Nd)i is in the range from0.51236 to 0.51248 and the εNd(t) is positive value (+0.79-+3.11); the (87Sr/86Sr)i is in the range from 0.7052 to 0.7054. These Nd and Sr isotopic composition features indicate that the source rocks of these adakite-type rocks are from a weakly depleted mantle, or a depleted mantle, but was contaminated by the crustal materials. These adakite-type rocks were most likely derived from the partial melting of new underplated basaltic rocks under the conditions of amphibo-lite to eclogite transition in the postcollisional environment of North Xinjiang during the Permian | XIONG Xiaolin ZHAO Zhenhua BAI Zhenghua MEI Houjun WANG Yixian WANG Qiang XU Jifeng Niu Hecai BAO Zhiwei | 2001 | Chinese Science Bulletin2001，46，10： | 25 |
| 3 | Geochemistry of Alkali-rich Igneous Rocks of Northern Xinjiang and Its Implications for Geodynamics显示文摘Five nearly E-W-trending alkali-rich igneous rock belts are distributed from north to south in northern Xinjiang, and they are composed mainly of riebeckite, K-feldspar granite and high-K and medium-K calc-alkaline volcanic rocks and shoshonite. They were mainly emplaced or erupted between the Carboniferous and Permian. The compositions of Sr, Nd, Pb, and O isotopes imply that their principal resource materials are derived from the upper mantle or juvenile crust, indicating obvious continental growth in the Phanerozoic. The trace element association implies that their tectonic settings are within plate and volcanic arc for alkali-rich granites, and post-collisional arc, late oceanic arc and continental arc for alkali-rich volcanic rocks. An archipelago model was suggested for the tectonic evolution in northern Xinjiang. It can be named the central-Asia-type orogeny, which is different from the so called circum-Pacific ocean-continent-type tectonics or the Alpine-Himalayan | ZHAO Zhenhua BAI Zhenghua XIONG Xiaolin MEI Houjun WANG Yixian | 2000 | Acta Geologica Sinica(English Edition)2000，74，2： | 16 |
| 4 | A blind quantum signature protocol using the GHZ states显示文摘Recently,some blind quantum signature(BQS) protocols have been proposed.But the previous schemes have security and efficiency problems.Based on the entangled Greenberger-Horne-Zeilinger(GHZ) states,a new weak BQS protocol is proposed.Compared with some existing schemes,our protocol has 100% efficiency.Besides,the protocol is simple and easy to implement.The security of the protocol is guaranteed by the correlation of the GHZ particles held by each participant.In our protocol,the signatory is kept blind from the content of the message.According to the security analysis,the signatory cannot disavowal his/her signature while the signature cannot be forged by others. | WANG MingMing CHEN XiuBo YANG YiXian | 2013 | Science China(Physics,Mechanics & Astronomy)2013，56，9： | 10 |
| 5 | The Chinese Hα Solar Explorer(CHASE) mission: An overview显示文摘The Chinese Hα Solar Explorer(CHASE), dubbed “Xihe”—Goddess of the Sun, was launched on October 14, 2021 as the first solar space mission of China National Space Administration(CNSA). The CHASE mission is designed to test a newly developed satellite platform and to acquire the spectroscopic observations in the Hα waveband. The Hα Imaging Spectrograph(HIS)is the scientific payload of the CHASE satellite. It consists of two observational modes: raster scanning mode and continuum imaging mode. The raster scanning mode obtains full-Sun or region-of-interest spectral images from 6559.7 to 6565.9 ? and from 6567.8 to 6570.6 ? with 0.024 ? pixel spectral resolution and 1 min temporal resolution. The continuum imaging mode obtains photospheric images in continuum around 6689 ? with the full width at half maximum of 13.4 ?. The CHASE mission will advance our understanding of the dynamics of solar activity in the photosphere and chromosphere. In this paper, we present an overview of the CHASE mission including the scientific objectives, HIS instrument overview, data calibration flow, and first results of on-orbit observations. | Chuan Li Cheng Fang Zhen Li MingDe Ding PengFei Chen Ye Qiu Wei You Yuan Yuan MinJie An HongJiang Tao XianSheng Li Zhe Chen Qiang Liu Gui Mei Liang Yang Wei Zhang WeiQiang Cheng JianXin Chen ChangYa Chen Qiang Gu QingLong Huang MingXing Liu ChengShan Han HongWei Xin ChangZheng Chen YiWei Ni WenBo Wang ShiHao Rao HaiTang Li Xi Lu Wei Wang Jun Lin YiXian Jiang LingJie Meng Jian Zhao | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，8： | 7 |
| 6 | Soil erosion and sediment interception by check dams in a watershed for an extreme rainstorm on the Loess Plateau,China显示文摘The magnitude of soil erosion and sediment load reduction efficiency of check dams under extreme rainstorms is a long-standing concern.The current paper aims to use check dams to deduce the amount of soil erosion under extreme rainstorms in a watershed and to identify the difference in sediment interception efficiency of different types of check dams.Based on the sediment deposition at 12 check dams with 100% sediment interception efficiency and sub-catchment clustering by taking 12 damcontrolled catchments as clustering criteria,the amount of soil erosion resulting from an extreme rainstorm event on July 26,2017(named '7·26' extreme rainstorm) was estimated in the Chabagou watershed in the hill and gully region of the Loess Plateau.The differences in the sediment interception efficiency among the check dams in the watershed were analyzed according to field observations at 17 check dams.The results show that the average erosion intensity under the '7-26' extreme rainstorm was approximately 2.03×10~4 t/km^2,which was 5 times that in the second largest erosive rainfall in 2017(4.15×10~3 t/km^2) and 11-384 times that for storms in 2018(0.53×10~2 t/km^2-1.81×10~3 t/km^2).Under the '7-26' extreme rainstorm,the amount of soil erosion in the Chabagou watershed above the Caoping hydrological station was 4.20 × 106 t.The sediment interception efficiency of the check dams with drainage canals(including the destroyed check dams) and with drainage culverts was 6.48 and 39.49%,respectively.The total actual sediment amount trapped by the check dams was 1.11 × 106 t,accounting for 26.36% of the total amount of soil erosion.In contrast,3.09×106 t of sediment were input to the downstream channel,and the sediment deposition in the channel was 2.23×10~6 t,accounting for 53.15%of the total amount of soil erosion.The amount of sediment transport at the hydrological station was8.60×10~5 t.The Sediment Delivery Ratio(SDR) under the '7·26' extreme rainstorm was 0.21.The results indicated that the amount of soil erosion was huge,and the sediment interception efficiency of the check dams was greatly reduced under extreme rainstorms.It is necessary to strengthen the management and construction technology standards of check dams to improve the sediment interception efficiency and flood safety in the watershed. | Leichao Bai Nan Wang Juying Jiao Yixian Chen Bingzhe Tang Haolin Wang Yulan Chen Xiqin Yan Zhijie Wang | 2020 | International Journal of Sediment Research2020，35，4： | 7 |
| 7 | Focal mechanism analysis and parameter estimation of Zhangbei-Shangyi earthquake from differential SAR inter-ferometry显示文摘On 10 January, 1998 an earthquake of Ms=6.2 occurred in the Zhangbei-Shangyi region of North China. The surface seismic deformation was measured in the previous study using the 3 pass ERS-1/2 SAR differential inter-ferometric technology (D-INSAR). In this note the focal mechanism of Zhangbei-Shangyi earthquake is estimated from the D-INSAR measurement of surface deformation based on a standard elastic dislocation model for seismic displacement. The inversion procedure is an iterative, linear least-squares algorithm. Through the relation between the focal parameters and displacement in the line of sight direc-tion measured in the radar interferogram, the optimum focal parameter set is derived. The results show that the seismic fault of Zhangbei-Shangyi earthquake is a thrust fault dip-ping SW with a large right-lateral displacement component. The strike and dip are 95°and 30°respectively on a fault patch of 12 km long by 14 km wide. Its hypocenter is located at N40°58’, E114°21’, and 7.5 km in depth. | ZHANG Hong WANG Chao SHAN Xinjian MA Jin TANG Yixian QUO Ziqi | 2002 | Chinese Science Bulletin2002，47，4： | 5 |
| 8 | Conjugate adjoining problem in braid groups and new design of braid-based signatures显示文摘The development of quantum computation casts serious threats to the securities of most existing public-key cryptosystems. Braid-based cryptography is one of the alternatives that have potential advantages in resisting quantum attacks. In this paper, the state of the art of braid cryptography is surveyed, and then a new cryptographic problem-conjugate adjoining problem related to braid groups is proposed. Based on this problem, we design a new braid-based signature scheme. This scheme is efficient and provably secure in the random oracle model. Further, we present the comparison between braid-based signatures and RSA-based ones. The signing process of the braid-based schemes is more efficient than that of RSA-based ones, while the verifying process of the braid-based ones is observably slow. Hence, braid-based signatures are suitable for scenarios where the signing process has to be as quick as possible but delays are permitted in the verifying process, for example, in off-line e-cash systems. The key sizes in braid-based schemes are considerably large-about 2K bits in the case of secret keys and 12K bits in the case of public keys. However, braid operations are much simpler and more efficient than modular exponential operations. Therefore, braid-based schemes can be embedded into devices with low computational ability and large memory space. The capability of braid cryptosystems to resist currently known quantum attacks is also discussed from the perspective of hidden subgroup problems. | WANG LiCheng WANG LiHua CAO ZhenFu YANG YiXian NIU XinXin | 2010 | Science China(Information Sciences)2010，53，3： | 3 |
| 9 | Linking microbial community composition to farming pattern in selenium-enriched region:Potential role of microorganisms on Se geochemistry显示文摘Selenium(Se)is an essential micronutrient for lives.Indigenous microbial communities play an important role on Se geochemistry in soils.In this study,the microbial community composition and functions of 53 soil samples were investigated using high-throughput sequencing.Samples were divided into 3 groups with different farming types based on the measured geochemical parameters and microbial functional structures.Results indicated that putative Se related bacteria Bacillus,Dyella,Paenibacillus,Burkholderia and Brevibacillus were dominant in dryland plantation soils which were characterized with higher available Se and low contents of H_(2)O,total organic carbon(TOC),NH_(4)^(+) and NO_(2)^(-).In contrast,the putative denitrifier Pseudomonas dominated in flooded paddy soils with higher TOC,NO_(3)^(-) and organic Se,whereas genera Rhizobium,Nitrosospira,and Geobacter preferred woodland soils with higher oxidation-reduction potential(ORP),pH,NH_(4)^(+) and Fe.Farming patterns resulted in distinct geochemical parameters including moisture,pH,ORP,TOC,and contents of soluble Fe,NO_(2)^(-) and NH_(4)^(+),shaping the microbial communities,which in turn affected Se forms in soils.This study provides a valuable insight into understanding of Se biogeochemistry in soils and prospective strategy for Se-rich agriculture production. | Yanhong Wang Xinyan Shi Xianxin Huang Chunlei Huang Helin Wang Hanqin Yin Yixian Shao Ping Li | 2022 | Journal of Environmental Sciences2022，34，2： | 3 |
| 10 | Highly efficient fluoride removal from water using 2D metal-organic frameworks MIL-53(Al)with rich Al and O adsorptive centers显示文摘In this study,metal-organic framework MIL-53(Al)was synthesized and studied to understand the different mechanisms between normal MIL-53(Al)and 2D metal-organic framework MIL-53(Al)for removing fluoride.Comparatively,the 2D MIL-53(Al)had two-dimensional linear morphology rather than block shape,indicating more expose adsorptive sites than normal MIL-53(Al).The batch adsorption experiments were applied to investigate the performance of 2D MIL-53(Al),including pH,adsorption kinetics,and thermodynamics.The 2D MIL-53(Al)(75.50 mg/g)showed better adsorption capacity than normal MIL-53(Al)(35.63 mg/g).The adsorption process of 2D MIL-53(Al)followed the pseudo-firstorder model and Langmuir model.The adsorption mechanism of this material was further studied by using experimental characterization and density functional theory calculations in detail.The main adsorptive sites were Al and O in the 2D MIL-53(Al),and the relationship between fluoride binding with Al and O was HF^(-)_(2)>HF>F^(-).The species of fluoride were HF2,HF,F at different pH and concentrations.Hence,this study provides a significant way on the application of two-dimensional materials for removing fluoride. | Lei Huang Zhihui Yang Sikpaam Issaka Alhassan Zhixuan Luo Baocheng Song Linfeng Jin Yixian Zhao Haiying Wang | 2021 | Environmental Science and Ecotechnology2021，，4： | 3 |
| 11 | Polarimetric synthetic aperture radar change detection for specific land cover types显示文摘This paper presents a supervised polarimetric synthetic aperture radar(PolSAR)change detection method applied to specific land cover types.For each pixel of a PolSAR image,its target scattering vector can be modeled as having a complex multivariate normal distribution.Based on this assumption,the joint distribution of two corresponding vectors in a pair of PolSAR images is derived.Then,a generalized likelihood ratio test statistic for the equality of two likelihood functions of such joint distribution is considered and a maximum likelihood distance measure for specific land cover types is presented.Subsequently,the Kittler and Illingworth minimum error threshold segmenta-tion method is applied to extract the specific changed areas.Experiments on two repeat-pass Radarsat-2 fully polarimetric images of Suzhou,China,demonstrate that the proposed change detection method gives a good performance in determining the specific changed areas in PolSAR images,especially the areas that have changed to water. | Meng Liu Hong Zhang Chao Wang Yixian Tang Bo Zhang Fan Wu Tao Wu Xi Chen | 2015 | International Journal of Digital Earth2015，8，4： | 2 |
| 12 | Retrieval of urban slow deformation using the multi-baseline DInSAR technique显示文摘The investigation of slow displacement in urban areas using the multi-baseline DInSAR technique has been a hot research topic in the field of DInSAR. The basic flow of this technique includes several steps such as the combination of interferometric image pairs, generation of differential interferograms, selection of high coherent points, generation of the Delaunay triangular network, calculation and integration of increments in network, unwrapping and calibration of the residual phase, and the estimation of both atmospheric and nonlinear displacement phase. Among these steps, the calculation of increments is the key to retrieve linear displacement, while unwrapping and calibration of the residual phase are the keys to retrieve nonlinear displacement. In order to improve the performance of these two steps, this paper proposes a modified model coherence function for increments estimation, and a triangular 'circle' algorithm to deal with phase unwrapping and calibration. Based on the above algorithms, the subsidence of Suzhou City is investigated using 24 ERS scenes from February 1993 to December 2000. The results show that the linear subsidence velocity of the most urban area is about -20 to -30 mm/a during the time, with a yearly decrease in velocity. The displacement seems to be stable after 2000. Leveling data validate our results and demonstrate the reliability of the algorithm. | WU mao ZHANG Hong WANG Chao TANG YiXian WU HongAn | 2008 | Chinese Science Bulletin2008，53，23： | 2 |
| 13 | Multi-scale mechanotransduction of the poroelastic signals from osteon to osteocyte in bone tissue显示文摘In order to quantify the poroelastic mechanical signals conduction and evaluate the biomechanical effectiveness of functional units(osteocyte processes,canaliculi and lacuna)in lacunar-canalicular system(LCS),a multiscale poroelastic finite element model was established by using the Comsol Multiphysics software.The poroelastic mechanical signals(pore pressure,fluid velocity,von-Mises stress,strain)were analyzed inside the osteon-osteocyte system.The effects of osteocyte(OCY)’s shape(ellipse and circle),long axis directions(horizontal and vertical)and mechanical properties(Elastic modulus and permeability)on its poroelastic responses were examined.It is found that the OCY processes is the best mechanosensor compared with the OCY body,lacunae and canaliculi.The mechanotransduction ability of the elliptic shaped OCY is stronger than that of circular shaped.The pore pressure and flow velocity around OCYs increase as the elastic modulus and permeability of OCY increase.The established model can be used for studying the mechanism of bone mechanotransduction at the multiscale level. | Xiaogang Wu Chaoxin Li Kuijun Chen Yuqin Sun Weilun Yu Meizhen Zhang Yanqin Wang Yixian Qin Weiyi Chen | 2020 | Acta Mechanica Sinica2020，36，4： | 2 |
| 14 | SLC1A1-mediated cellular and mitochondrial influx of R-2-hydroxyglutarate in vascular endothelial cells promotes tumor angiogenesis in IDH1-mutant solid tumors显示文摘Muta nt isocitrate dehydrog en ase 1(mlDH1)drives tumorigenesis via produci ng on cometabolite R-2-hydroxyglutarate(R-2-HG)across various tumor types.However,mlDHl in hibitors appear only effective in hematological tumors.The therapeutic ben efit in solid tumors remains elusive,likely due to the complex tumor microenvironment.In this study,we discover that R-2-HG produced by IDH1-mutant tumor cells is preferentially imported into vascular endothelial cells and remodels mitochondrial respiration to promote tumor angiogenesis,conferring a therapeutic vulnerability in IDH1-mutant solid tumors.Mechanistically,SLC1 Alz a Na'-depe ndent glutamate tran sporter that is prefere ntially expressed in en dothelial cells,facilitates the in flux of R-2-HG from the tumor microenvironment into the endothelial cells as well as the intracellular trafficking of R-2-HG from cytoplasm to mitochondria.R-2-HG hijacks SLC1A1 to promote mitochondrial Na^(+)/Ca^(2+)exchange,which activates the mitochondrial respiratory chain and fuels vascular en dothelial cell migratio n in tumor an giogenesis.SLC1A1 deficiency in mice abolishes mlDHl-promoted tumor an giogenesis as well as the therapeutic benefit of mlDHl in hibitor in solid tumors.Moreover,we report that HH2301,a newly discovered mlDHl inhibitor,shows promising efficacy in treating IDH1-mutant cholangiocarcinoma in preclinical models.Together,we identify a new role of SLC1A1 as a gatekeeper of R-2-HG-mediated crosstalk between IDH1-mutant tumor cells and vascular en dothelial cells,and dem on strate the therapeutic potential of mlDHl in hibitors in treating IDH1-muta nt solid tumors via disrupting R-2-HG-promoted tumor angiogenesis. | Xiaomin Wang Ziqi Chen Jun Xu Shuai Tang Nan An Lei Jiang Yixiang Zhang Shaoying Zhang Qingli Zhang Yanyan Shen Shijie Chen Xiaojing Lan Ting Wang Linhui Zhai Siyuwei Cao Siqi Guo Yingluo Liu Aiwei Bi Yuehong Chen Xiameng Gai Yichen Duan Ying Zheng Yixian Fu Yize Li Liang Yuan Linjiang Tong Kun Mo Mingcheng Wang Shu-Hai Lin Minjia Tan Cheng Luo Yi Chen Jia Liu Qiansen Zhang Leping Li Min Huang | 2022 | Cell Research2022，32，7： | 2 |
| 15 | Highly evolved juvenile granites with tetrad REE patterns: The Woduhe and Baerzhe granites from the Great Xing'an Mountains in NE China显示文摘 | Jahn Bor-ming Wu Fuyuan Capdevila R Martineau F Zhao Zhenhna Wang Yixian | 2001 | Lithos2001，59，4： | 1 |
| 16 | Novel single-channel color image encryption algorithm based on chaos and frac- tional Fourier transform显示文摘 | Zhou Nanrun Wang Yixian | 2011 | Opt Commun2011，284，12： | 1 |
| 17 | Impedimetric immuno sensor based on gold nanoparticles modified graphenepaper for label- free detection of Eseherichiaeoli 0157 : H7显示文摘 | WANG Yixian PING Jianfeng | 2013 | Biosensors and Bioelectronics2013，49，： | 1 |
| 18 | Proterozoic anorogenic magmatic rocks and their constraints on mineralizations in the Bayan Obo deposit region, Inner Mongolia显示文摘 | Yixian Wang Yuzhuo Qiu Jiyuan Gao Qian Zhang | 2003 | Science in China Series D: Earth Sciences2003，，1： | 1 |
| 19 | Va-lidation on retrieving land surface parameters using SMMR data in Takelamgan显示文摘 | Zhang Weiguo Tang Yixian Wang Chao | 2004 | IGARSS2004，6，： | 1 |
| 20 | Colloidal crystals self-assembled on the end face of fiber:fabrication and characterizations显示文摘 | Yan Haitao Wang Ming Ce Yixian | 2009 | Optical Fiber Technology2009，，15： | 1 |
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