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| 1 | Phytochrome B interacts with SWC6 and ARP6 to regulate H2A.Z deposition and photomorphogensis in Arabidopsis显示文摘Light serves as a crucial environmental cue which modulates plant growth and development, and which is controlled by multiple photoreceptors including the primary red light photoreceptor,phytochrome B(phyB). The signaling mechanism of phyB involves direct interactions with a group of basic helix-loop-helix(bHLH) transcription factors, PHYTOCHROME-INTERACTING FACTORS(PIFs), and the negative regulators of photomorphogenesis, COP1 and SPAs. H2 A.Z is an evolutionarily conserved H2 A variant which plays essential roles in transcriptional regulation. The replacement of H2 A with H2 A.Z is catalyzed by the SWR1 complex. Here, we show that the Pfr form of phyB physically interacts with the SWR1 complex subunits SWC6 and ARP6. phyB and ARP6 coregulate numerous genes in the same direction,some of which are associated with auxin biosynthesis and response including YUC9, which encodes a rate-limiting enzyme in the tryptophandependent auxin biosynthesis pathway. Moreover,phyB and HY5/HYH act to inhibit hypocotyl elongation partially through repression of auxin biosynthesis. Based on our findings and previous studies, we propose that phyB promotes H2 A.Z deposition at YUC9 to inhibit its expression through direct phyB-SWC6/ARP6 interactions,leading to repression of auxin biosynthesis, and thus inhibition of hypocotyl elongation in red light. | Xuxu Wei Wanting Wang Peng Xu Wenxiu Wang Tongtong Guo Shuang Kou Minqing Liu Yake Niu Hong-Quan Yang Zhilei Mao | 2021 | Journal of Integrative Plant Biology2021，63，6： | 6 |
| 2 | Observation of double indirect interlayer exciton in MoSe_(2)/WSe_(2) heterostructure显示文摘Interlayer excitons(IXS)are electron–hole pairs bound in the spatial separation layer by the Coulomb effect,and their lifetime is several orders of magnitude longer than that of direct excitons,providing an essential platform for long-lived exciton devices.The recent emergence of the van der Waals heterostructure(HS),which combines two layers of different transitional metal dichalcogenides(TMDs),has created new opportunities for IX research.Herein,we demonstrate the observation of double indirect interlayer excitons in the MoSe_(2)/WSe_(2)HS using photoluminescence(PL)spectroscopy.The intensities of the two peaks are essentially the same,and the energy difference is 22 meV,which is perfectly in line with the calculation result of density functional theory.Furthermore,the experience of variable excitation power also proves that the splitting of the IXs originates from the conduction band spin-splitting of MoSe_(2).The observation results provide a promising platform for further exploring the new physical properties and optoelectronic phenomena of TMD HS. | Biao Wu Yunpeng Wang Jiahong Zhong Cheng Zeng Yassine Madoune Wanting Zhu Zongwen Liu Yanping Liu | 2022 | Nano Research2022，15，3： | 3 |
| 3 | Activation of extrasynaptic GABA_A receptors inhibits cyclothiazideinduced epileptiform activity in hippocampal CA1 neurons显示文摘Extrasynaptic GABA_A receptors(GABA_ARs)-mediated tonic inhibition is reported to involve in the pathogenesis of epilepsy.In this study,we used cyclothiazide(CTZ)-induced in vitro brain slice seizure model to explore the effect of selective activation of extrasynaptic GABA_ARs by 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridine-3-ol(THIP)on the CTZ-induced epileptiform activity in hippocampal neurons.Perfusion with CTZ dose-dependently induced multiple epileptiform peaks of evoked population spikes(PSs)in CA1 pyramidal neurons,and treatment with THIP(5 umol/L)significantly reduced the multiple PS peaks induced by CTZ stimulation.Western blot showed that the 5-subunit of the GABA_AR,an extrasynaptic specific GABA_AR subunit,was also significantly down-regulated in the cell membrane 2h after CTZ treatment.Our results suggest that the CTZ-induced epileptiform activity in hippocampal CA1neurons is suppressed by the activation of extrasynaptic GABA_ARs,and further support the hypothesis that tonic inhibition mediated by extrasynaptic GABA_ARs plays a prominent role in seizure generation. | Li Wan Xu Liu Zheng Wu Wanting Ren Shuzhen Kong Raya Abou Dargham Longzhen Cheng Yun Wang | 2014 | Neuroscience Bulletin2014，30，5： | 3 |
| 4 | Development and Evaluation of a Wearable Lower Limb Rehabilitation Robot显示文摘This paper introduces a rigid-flexible coupling wearable exoskeleton robot for lower limb,which is designed in light of gait biomechanics and beneficial for low limb movement disorders by implementing gait training.The rationality of the proposed mechanism is shown with the implementation of the dynamic simulation through MSC ADAMS.For the purposes of lightweight,the exoskeleton mechanism is optimized through finite element analysis.It can be concluded from performance evaluation experiment,the mechanism has certain advantages over existing exoskeleton robots,namely,comfortable,lightweight,low cost,which can be utilized for rehabilitation training in medical institutions or as a daily-walking ancillary equipment for patients. | Wanting Li Keping Liu Chunxu Li Zhongbo Sun Shui Liu Jian Gu | 2022 | Journal of Bionic Engineering2022，19，3： | 2 |
| 5 | Comparison of the differentiation of dental pulp stem cells and periodontal ligament stem cells into neuron-like cells and their effects on focal cerebral ischemia显示文摘Recent studies have reported an in creasing in cidence of ischemic stroke,particularly in younger age groups.Dental pulp stem cells(DPSCs)and periodontal ligament stem cells(PDLSCs)are the most comm on stem cells acquired from the teeth of adults,even elderly people.However,there are no detailed reports on whether DPSCs or PDLSCs are suitable for the treatment of ischemic stroke.In this study,the in vitro differentiation of DPSCs and PDLSCs into neuron-like cells was evaluated.Then,we established a rat model of cerebral ischemia.DPSCs or PDLSCs were administered to animals,and the therapeutic effects of these two types of cells were investigated.The results showed that PDLSCs had a higher differentiation rate than DPSCs.Immunofluorescence studies showed that the expression of the neuronal differentiation markerThy-1 was higher in PDLSCs than in DPSCs,and other gene markers of neuronal differentiation showed corresponding trends,which were confirmed by western blot analysis.In this process,the Notch and Wnt signaling pathways were inhibited and activated,respectively.Fin ally,rats with transient occlusion of the right middle cerebral artery were used as a model to assess the therapeutic effect of PDLSCs and DPSCs on ischemia.The results showed that rats in the PDLSC-treated group emitted significantly greater red fluorescence signal than the DPSC-treated group.PDLSC transplantation promoted the recovery of neurological function more effectively than DPSC transplantation.Hence,PDLSCs represent an autogenous source of adult mesenchymal stem cells with desirable biological properties and may be an ideal candidate for clinical applications. | Tingting Wu Wanting Xu Hanlin Chen Shasha Li Rengang Dou Hongtao Shen Xue Liu Xiaoyu Liu Yongfeng Hong Jiacai He | 2020 | Acta Biochimica et Biophysica Sinica2020，52，9： | 2 |
| 6 | Molecular Mechanism of Induction on Apoptosis of Human Esophageal Cancer HCE-4 Cells by Active Components from Astragalus membranaceus显示文摘[Objectives] To investigate the pharmacologic effects of active components from A. membranaceus on human esophageal cancer HCE-4 cells and its apoptosis mechanism. [Methods] The viabilities of HCE-4 cells were measured by MTT assay. The induction of active components from A. membranaceus on apoptosis of HCE-4 cells was detected by Annexin V-FITC/PI double staining. The apoptotic-related protein expression levels were determined by Western blotting. [Results] Formononetin and astragaloside IV suppressed the proliferation of HCE-4 cells in a dose-dependent manner. The Annexin V-FITC/PI double staining results showed that formononetin and astragaloside IV could induce HCE-4 cells apoptosis in a time-dependent manner. The Western blotting results showed that formononetin and astragaloside IV could significantly down-regulate p-AKT,pro-caspase-3,and increase cle-caspase-3 protein expression in HCE-4 cells. [Conclusions]Active components from A. membranaceus such as formononetin and astragaloside IV significantly inhibited the proliferation of human esophageal cancer HCE-4 cells by inducing mitochondrial dependent apoptosis via AKT signaling pathway. | Jiaru WANG Yinghua LUO Xianji PIAO Chang LIU Yi ZHANG Hao WANG Jinqian LI Wanting XU Yang LIU Yiqin WU Chenghao JIN | 2018 | Medicinal Plant2018，9，1： | 2 |
| 7 | Bearing Failure Optimization of Composite Double-Lap Bolted Joints Based on a Three-Step Strategy Marked By Feasible Region Reduction and Model Decoupling显示文摘To minimize the mass and increase the bearing failure load of composite double-lap bolted joints,a three-step optimization strategy including feasible region reduction,optimization model decoupling and optimization was presented.In feasible region reduction,the dimensions of the feasible design region were reduced by selecting dominant design variables from numerous multilevel parameters by sensitivity analyses,and the feasible regions of variables were reduced by influence mechanism analyses.In model decoupling,the optimization model with a large number of variables was divided into various sub-models with fewer variables by variance analysis.In the third step,the optimization sub-models were solved one by one using a genetic algorithm,and the modified characteristic curve method was adopted as the failure prediction method.Based on the proposed optimization method,optimization of a double-lap single-bolt joint was performed using the ANSYS®code.The results show that the bearing failure load increased by 13.5%and that the mass decreased by 8.7%compared with those of the initial design of the joint,which validated the effectiveness of the three-step optimization strategy. | Fengrui Liu Wanting Yao Xinhong Shi Libin Zhao Jianyu Zhang | 2020 | Computers, Materials & Continua2020，，2： | 1 |
| 8 | Drainage evolution in intermontane basins at the Qinling-Daba Mountains显示文摘River capture is of great significance to landform evolution and hominine migration.In the Qinling-Daba Mountains,there is a viewpoint that Jialing River captured Hanjiang River,but this is still controversial.In this paper,we discuss the drainage evolution processes in intermountain basins at the Qinling-Daba Mountains based on a combination of detrital zircon UPb geochronology and geomorphic indexes.We suggest that the Hanjiang River gradually captured the Jialing River from east to west,accompanied by the evolution of the ancient Yangtze River.In terms of geomorphic evidences,wide valleys did not match with discharge,and a series of wind gaps developed in the Shiquan-Ankang basin.In addition,the valley shapes and width-toheight ratios(Vf)indicate two possible rapid incisions.The hypsometric integrals(HI)reflect that the landform gradually changes from the old stage to the youth stage from west to east.Theχvalues show that the drainage divide is moving to the side of the Yuehe River,and the Yuehe River is gradually shrinking.According to the sedimentary records,the zircon U-Pb age distributions indicate the provenance change.The high-altitude terraces show three age peaks(200–250,400–505,and 700–900 Ma),with the dominant Indosinian age peak(200–250 Ma),while the modern fluvial sediments only show a single peak of Jinning(700–900 Ma).These data show that there are two major river captures:(1)The ancient Hanjiang River cut through the regional compression ridge,and then captured the Hanzhong Basin river system(a part of the ancient Jialing river system)from east to west,and(2)The southern tributary captured the trunk with the uplift of the divide in the Shiquan-Ankang Basin,forming the modern drainage pattern in the upper Hanjiang River.The activities of the regional strike-slip fault,and the associated compression uplift played a key role in the river captures,the drainage evolution,and related landforms in the Shiquan-Ankang basin.In addition,it is shown that the evolution of the upper tributary basins lagged behind the response of the trunk channel to the tectonic activities and river captures.The interconnected wide valleys caused by river capture may have provided convenient geomorphological conditions for human migration into the Qinling-Daba Mountains along those river valleys. | Wanting XIE Xianyan WANG Hanzhi ZHANG Quanyu LIU Shejiang WANG Huayu LU | 2021 | Science China Earth Sciences2021，64，11： | 1 |
| 9 | Poly(ether ether ketone ketone) based imidazolium as anion exchange membranes for alkaline fuel cells显示文摘An imidazolium functionalized poly(ether ether ketone ketone)(PEEKK-DIm OH)anion exchange membrane(AEM)readily soluble in certain low-boiling-point solvents(isopropanol)is prepared.The solubility results are consistent with the results of molecular dynamics simulations.By varying the chloromethylation reaction temperature or concentrated sulfuric acid concentration of PEEKK,the degrees of chloromethylation of PEEKK are changed from 54% to 92%,the corresponding PEEKK-DIm OH AEMs with the ion exchange capacities(IECs)of 1.14–1.65 mmol·g^(-1).The PEEKK-DIm OH 92% AEM shows high hydroxide conductivity(31 m S·cm^(-1)),suitable water uptake(94%)and acceptable swelling ratio(39%)at 60°C.In addition,the PEEKK-DIm OH AEMs possess good thermal and alkaline stability.The maximum power density(46.16 mW·cm^(-2))of fuel cell prepared with PEEKK-DIm OH 92%AEM as exchange membrane and ionomer is much higher than that with commercial AHA membranes.All the above results indicate that the PEEKK used in this study is a promising AEM matrix material for alkaline fuel cells. | Tiantian Li Xuemei Wu Wanting Chen Xiaoming Yan Dongxing Zhen Xue Gong Jiafei Liu Shaofeng Zhang Gaohong He | 2018 | Chinese Journal of Chemical Engineering2018，26，10： | 1 |
| 10 | Novel heat shock protein Hsp70L1 activates dendritic cells and acts as a Th1 polarizing adjuvant显示文摘Heat shock proteins (HSPs) are reported to act as effective adjuvants to elicit anti-tumor and anti-infection immunity. Here, we report that Hsp70-like protein 1 (Hsp70L1), a novel HSP derived from human dendritic cells (DCs), has potent adjuvant effects that polarize responses toward Th1. With a calculated molecular weight of 54.8 kDa, Hsp70L1 is smaller in size than Hsp70 but resembles it both structurally and functionally. Hsp70L1 shares common receptors on DCs with Hsp70 and can interact with DCs, promoting DC maturation and stimulating secretion of the proinflammatory cytokines interleukin 12p70 (IL-12p70), IL-1beta, tumor necrosis factor-alpha (TNF-alpha), and the chemokines IP-10, macrophage inflammatory protein-1alpha (MIP-1alpha), MIP-1beta, and normal T cell expressed and secreted (RANTES). The induction of interferon-gamma-inducible protein 10 (IP-10) secretion by Hsp70L1 is not shared by Hsp70, and other functional differences include more potent stimulation of DC IL-12p70, CC-chemokine, and CCR7 and CXCR4 expression by Hsp70L1. Immunization of mice with the hybrid peptide Hsp70L1-ovalbumin(OVA)(257-264) induces an OVA(257-264)-specific Th1 response and cytotoxic T lymphocyte (CTL) that results in significant inhibition of E.G7-OVA tumor growth. The ability of Hsp70L1 to activate DCs indicates its potential as a novel adjuvant for use with peptide immunizations; the Hsp70L1 antigen peptide hybrid may serve as a more effective vaccine for the control of cancer and infectious diseases. | WanT ZhouX ChenG AnH ChenT ZhangW LiuS JiangY YangF WuY CaoX | 2005 | 第二军医大学学报2005，26，7： | 1 |
| 11 | Proton induced single event upset cross section prediction for 0.15 μm six-transistor (6T) silicon-on-insulator static random access memories显示文摘 | Lei Li Wanting Zhou Huihua Liu | 2012 | Journal of Nuclear Science and Technology2012，，： | 1 |
| 12 | Post-hurricane forest damage assessment using satellite remote sensing显示文摘 | Wanting Wang John J. Qu Xianjun Hao Yongqiang Liu John A. Stanturf | 2009 | Agricultural and Forest Meteorology2009，，1： | 1 |
| 13 | Effects of organic acids on copper and cadmium desorption from contaminated soils显示文摘 | Yanzheng Gao Jizheng He Wanting Ling Hongqing Hu Fan Liu | 2003 | Environment International2003，，5： | 1 |
| 14 | An improved algorithm for small and cool fire detection using MODIS data: A preliminary study in the southeastern United States显示文摘 | Wanting Wang John J. Qu Xianjun Hao Yongqiang Liu William T. Sommers | 2006 | Remote Sensing of Environment2006，，2： | 1 |
| 15 | Lignin derived absorbent for efficient and sustainable CO_(2) capture显示文摘High and cost-efficient capture of CO_(2) is a prerequisite and an inevitable path of carbon emission reduction. To address the challenges(high cost, low efficiency, less sustainability, etc.) of existing petroleum-based CO_(2) absorbents, herein, a class of efficient and sustainable lignin-based absorbents were resoundingly prepared by grafting the active amine group on a lignin derived compound vanillin and alkali lignin. The results demonstrated that vanillin modified by acrylamide achieved the excellent absorption capacity among the three absorbents, whose ability was 0.114 g CO_(2) per gram of absorbent under 25 ℃ and 100 kPa. In addition, the absorbent retained stable absorbability of CO_(2) after 6 cycles.The absorbing capacity of the absorbent formed by the coupling of vanillin and acrylamide to CO_(2) was much greater than their own(i.e. 0 g CO_(2) ·g^(-1)vanillin, 0.01 g CO_(2) ·g^(-1) acrylamide, respectively).Detailed information revealed the multi-site synergistic absorption mechanism, in which CO_(2) has C and O double interactions with the amide group of the absorbent, and single interaction with the hydroxyl oxygen on the benzene ring of the absorbent. The absorption capacity of modified lignin for CO_(2) is as high as 0.12 g CO_(2) per gram of absorbent, which is comparable with that of model compound vanillin.This work not only provides a new idea for the design of bio-absorbents for CO_(2) capture, but explores the application potential of lignin-based materials. | Yuandong Cui Bin He Yu Lei Yu Liang Wanting Zhao Jian Sun Xiaomin Liu | 2023 | Chinese Journal of Chemical Engineering2023，54，2： | 0 |
| 16 | Development and validation of prognostic implications of chromosome abnormalities algorithm for newly diagnosed multiple myeloma显示文摘Fluorescence in situ hybridization(FISH)evaluation is essential for initial risk stratification in multiple myeloma(MM).The presence of specific cytogenetic abnormalities(CA)confers a heterogeneity impact on prognosis.However,the cutoff values among different centers are not uniform.Therefore,we conduct this study to better predict the prognosis of newly diagnosed MM patients based on FISH results.The Kaps method was used to calculate the chromosomal abnormal cutoff values.A total of 533 participants were included in the study.The best cutoff value of overall survival were as follows:17p20.1%,13q85%,1q21+39%,t(11;14)55.5%,t(14;16)87%,and t(4;14)53.5%.The survival analysis showed that 17pand 1q21+were the independent factors affecting both OS and progress free survival(PFS)among CA.The analysis based on the cutoff value obtained by Kaps suggested that 13q,t(14;16),17p,and 1q21+were independent factors affecting OS among CA;t(14;16),17p,and 1q21+were independent factors affecting PFS among CA.The prognostic model was constructed by the Kaps method with the Harrell concordance index(c-index)at 0.719(95%CI,0.683–0.756;corrected 0.707),which was higher than that calculated by the European Myeloma Network criteria(0.714;95%CI,0.678–0.751;corrected 0.696).In conclusion,chromosomal abnormalities in different proportions and combinations can affect the prognosis ofMMpatients.Therefore,effective criteria should be formulated to evaluate the prognosis ofMMpatients better. | Tiancheng Luo Wanting Qiang Jing Lu Haiyan He Jin Liu Lu Li Hua Jiang Weijun Fu Juan Du | 2021 | Blood Science2021，3，3： | 0 |
| 17 | Rice disease identification method based on improved CNN-BiGRU显示文摘In the field of precision agriculture,diagnosing rice diseases from images remains challenging due to high error rates,multiple influencing factors,and unstable conditions.While machine learning and convolutional neural networks have shown promising results in identifying rice diseases,they were limited in their ability to explain the relationships among disease features.In this study,we proposed an improved rice disease classification method that combines a convolutional neural network(CNN)with a bidirectional gated recurrent unit(BiGRU).Specifically,we introduced a residual mechanism into the Inception module,expanded the module's depth,and integrated an improved Convolutional Block Attention Module(CBAM).We trained and tested the improved CNN and BiGRU,concatenated the outputs of the CNN and BiGRU modules,and passed them to the classification layer for recognition.Our experiments demonstrate that this approach achieves an accuracy of 98.21%in identifying four types of rice diseases,providing a reliable method for rice disease recognition research. | Yang Lu Xiaoxiao Wu Pengfei Liu Hang Li Wanting Liu | 2023 | Artificial Intelligence in Agriculture2023，，3： | 0 |
| 18 | A third dose of inactivated SARS-CoV-2 vaccine induces robust antibody responses in people with inadequate response to two-dose vaccination显示文摘Mass application of SARS-CoV-2 vaccines is a major approach to reduce SARS-CoV-2 transmission and COVID19 symptoms worldwide.The inactivated SARS-CoV-2 vaccine is one of the most widely administered vaccine types in many countries,with over 2 billion doses administered as of 31 August 2021.However,clinical trials estimate 65%–85%protection from detectable symptoms for inactivated SARS-CoV-2 vaccines[1–4],with 15%–35%of people remaining insufficiently protected after two-dose immunization.Immune protectionforthese‘non-responders’is critical for population immunity as established by mass vaccination.A third dose of inactivated(CoronaVac)vaccine has been shown to boost antibody response by between 3–5 folds in the general population[5].Whether a third dose can induce an adequate antibody response in‘non-responders’remains unclear.Here we report a trial of a third dose in a cohort of 105 vaccinated participants(Supplementary Fig.S1)with suboptimal antibody responses(non-responders)aftertwo doses(43.8%were men;average age 43±11 years[±SD];average BMI 23.5±3.4[±SD],Supplementary Table S1). | Taicheng Zhou Tianpei Shi Ao Li Lingzhi Zhu Xinshuai Zhao Naiyin Mao Wanting Qin Hanfang Bi Mei Yang Muxian Dai Fengwei Liu Rong Wang Wei Su Liang Zhang Wenbo Xu Jia Wei Zijie Zhang | 2022 | National Science Review2022，9，7： | 0 |
| 19 | Ensemble Learning Based on GBDT and CNN for Adoptability Prediction显示文摘By efficiently and accurately predicting the adoptability of pets,shelters and rescuers can be positively guided on improving attraction of pet profiles,reducing animal suffering and euthanization.Previous prediction methods usually only used a single type of content for training.However,many pets contain not only textual content,but also images.To make full use of textual and visual information,this paper proposed a novel method to process pets that contain multimodal information.We employed several CNN(Convolutional Neural Network)based models and other methods to extract features from images and texts to obtain the initial multimodal representation,then reduce the dimensions and fuse them.Finally,we trained the fused features with two GBDT(Gradient Boosting Decision Tree)based models and a Neural Network(NN)and compare the performance of them and their ensemble.The evaluation result demonstrates that the proposed ensemble learning can improve the accuracy of prediction. | Yunfan Ye Fang Liu Shan Zhao Wanting Hu Zhiyao Liang | 2020 | Computers, Materials & Continua2020，，11： | 0 |
| 20 | Higher efficacy of oral etoposide for mobilization of peripheral blood stem cells in patients with multiple myeloma显示文摘This study compares the efficacy,toxicity,hematopoietic recovery,and cost of stem-cell mobilization using intermediate-dose cyclophosphamide(IDCy)plus granulocyte colony-stimulating factor(G-CSF)compared with etoposide(VP-16)plus pegylated granulocyte colony-stimulating factor(PEG-rhG-CSF)in multiple myeloma(MM)patients.Two hundred forty-four consecutive patients undergoing mobilization with IDCy(3-3.5g/m^(2))plus G-CSF(n=155)were compared with patients receiving VP-16 plus PEG-rhG-CSF(n=89),including oral etoposide(n=65)and intravenous etoposide(n=24).Compared with IDCy,VP-16 use was associated with significantly higher median peak peripheral blood CD34+cell count(8.20[range:1.84-84]×10^(6)/kg vs 4.58[range:0.1-27.9]×10^(6)/kg,P=.000),and ideal CD34+cell yield of more than 6×10^(6)/kg(56.8%vs 35.1%,P=.001),notably with a higher efficacy in oral VP-16 use compared with IDCy use(CD 34+cell counts:median peak peripheral blood 5.87 vs 4.58?106/kg and≥6×10^(6)/kg[48.4%vs 35.1%]).The median number of apheresis courses was reduced from two in the IDCy group to one in the VP-16 group(P=.000).IDCy use was associated with significantly more frequent episodes of neutropenia(70.2%vs 35.2%;P=.000),intravenous antibiotic use(13.2%vs 11.4%;P=.672),and hospitalization(P=.000).The recoveries of neutrophils and platelets after autologous stem-cell transplantation were significantly faster in the VP-16 group compared with the IDCy group(P=.000).Our data indicate robust stem-cell mobilization in MM patients with VP-16 delivered either orally or intravenously.When compared with intravenous VP-16,oral VP-16 mobilization was associated with significantly more convenient,lower average total costs,and especially decreased the risk of hospital visits and exposure. | Wanting Qiang Hua Jiang Pei Guo Jing Lu Jin Liu Lu Li Haiyan He Xiaoxia Hu Weijun Fu Juan Du | 2022 | Blood Science2022，4，2： | 0 |
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