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| 1 | dentification of TRA2B-DNAH5 fusion as a novel oncogenic driver in human lung squamous cell carcinoma显示文摘 | Fei Li Zhaoyuan Fang Jian Zhang Chen Li Hongyan Liu Jufeng Xia Hongwen Zhu Chenchen auo Zhen Qin Fuming Li Xiangkun Han Yuetong Wang Yan Feng Ye Wang Wenjing Zhang Zuoyun Wang Yujuan Jin Yihua Sun Wenyi Wei Rong Zeng Haiquan Chen Hongbin Ji | 2016 | Cell Research2016,26,10: | 9 |
| 2 | Utilization of Ogura CMS germplasm with the clubroot resistance gene by fertility restoration and cytoplasm replacement in Brassica oleracea L显示文摘Clubroot disease,a major plant root disease caused by Plasmodiophora brassicae,has become one of the most destructive diseases among cultivated cruciferous vegetables.However,clubroot-resistant Brassica oleracea materials are rare.A few clubroot-resistant cabbage varieties are available on the market,but all are Ogura cytoplasmic male sterile(CMS)types.Therefore,in this study,to reutilize the clubroot-resistant Ogura CMS germplasm of cabbage,a new fertility-restored Ogura CMS material,16Q2-11,was used as a bridge to transfer the clubroot resistance(CR)gene from the Ogura CMS cytoplasm to the normal cytoplasm by a two-step method(a fertility restoration and cytoplasm replacement method).In the first cross for fertility restoration of Ogura CMS clubroot-resistant cabbage(FRCRC),16Q2-11 was used as a restorer to cross with Ogura CMS materials containing the CR gene CRb2.Eleven Rfo-positive progenies were generated,of which four contained CRb2:F8-514,F8-620,F8-732 and F8-839.After inoculation with race 4 of P.brassicae,these four CRb2-positive individuals showed resistance.Furthermore,F8-514 and F8-839 were then used as male parents in the second cross of FRCRC to cross with cabbage inbred lines,resulting in the successful introgression of the CRb2 gene into the inbred lines.All offspring produced from this step of cross,which had a normal cytoplasm,showed a high resistance to race 4 of P.brassicae and could be utilized for the breeding of clubrootresistant cabbage varieties in the future.This is the first time that the Ogura CMS restorer has been used to restore the fertility of Ogura CMS clubroot-resistant cabbages,which could improve germplasm diversity in cabbage and provide a reference method for using CMS germplasm in Brassica crops. | Wenjing Ren Zhiyuan Li Fengqing Han Bin Zhang Xing Li Zhiyuan Fang Limei Yang Mu Zhuang Honghao Lv Yumei Liu Yong Wang Hailong Yu Yangyong Zhang | 2020 | Horticulture Research2020,7,1: | 7 |
| 3 | Tianwen-1 MINPA observations in the solar wind显示文摘The Mars Ion and Neutral Particle Analyzer(MINPA)is one of the three scientific instruments onboard the Tianwen-1 orbiter to investigate the Martian space environment.During Tianwen-1’s transfer orbit to Mars,the MINPA was switched on to measure the solar wind ions.Here,we present the first results of the MINPA observations in the solar wind.During cruise,nearly half of the MINPA ion field-of-view(FOV)was blocked by the lander capsule;thus only the solar-wind ions with azimuthal speeds pointing towards the unblocked FOV sectors could be detected.We perform a detailed comparison of the MINPA’s solar wind observations with data from Earth-based missions when MINPA reached its count-rate peak,finding a general consistency of the ion moments between them.The blocking effect due to the lander is evaluated quantitatively under varying solar-wind velocity conditions.Despite the blocking effect,the MINPA’s solar wind measurements during the transfer orbit suggest a good performance. | AiBing Zhang LingGao Kong WenYa Li Lei Li BinBin Tang ZhaoJin Rong Yong Wei JiJie Ma YiTeng Zhang LiangHai Xie YuXian Wang JianSen He Bin Liu WenJing Wang Bin Su JiaWei Li Xu Tan Fang Wang TaiFeng Jin FuHao Qiao Peter Wurz Yan Zhu YunFei Bai YiRen Li XinBo Zhu YueQiang Sun YongLiao Zou Chi Wang | 2022 | Earth and Planetary Physics2022,6,1: | 5 |
| 4 | Human rhinovirus C infection is associated with asthma in children determined by x TAG respiratory viral panel FAST显示文摘Dear Editor,Cumulative evidence supports the role of early-life viral infections,especially respiratory syncytial virus(RSV)and human rhinovirus(HRV),as major antecedents of childhood asthma(Lemanske,2002;Jackson et al.,2008).In this study,the x TAG respiratory viral panel FAST(RVP FAST)assay,a multiplex polymerase chain reaction(PCR)-based method(Arens et al.,2010;BaladaLlasat et al.,2011;Gharabaghi et al.,2011;Selvaraju,2012),was used to investigate the association of infec- | Dongmei Chen Qinwei Song Runan Zhu Yuan Qian Yu Sun Jie Deng Fang Wang Yaxin Ding Run Tian Chuanhe Liu Wenjing Zhu Linqing Zhao | 2017 | Virologica Sinica2017,32,2: | 5 |
| 5 | Pristine PN junction toward atomic layer devices显示文摘In semiconductor manufacturing,PN junction is formed by introducing dopants to activate neighboring electron and hole conductance.To avoid structural distortion and failure,it generally requires the foreign dopants localize in the designated micro-areas.This,however,is challenging due to an inevitable interdiffusion process.Here we report a brand-new junction architecture,called'layer PN junction',that might break through such limit and help redefine the semiconductor device architecture.Different from all existing semiconductors,we find that a variety of van der Waals materials are doping themselves from n-to p-type conductance with an increasing/decreasing layer-number.It means the capability of constructing homogeneous PN junctions in monolayers'dimension/precision,with record high rectification-ratio(>10^(5))and low cut-off current(<1 pA).More importantly,it spawns intriguing functionalities,like gate-switchable-rectification and noise-signal decoupled avalanching.Findings disclosed here might open up a path to develop novel nanodevice applications,where the geometrical size becomes the only critical factor in tuning charge-carrier distribution and thus functionality. | Hui Xia Man Luo Wenjing Wang Hailu Wang Tianxin Li Zhen Wang Hangyu Xu Yue Chen Yong Zhou Fang Wang Runzhang Xie Peng Wang Weida Hu Wei Lu | 2022 | Light(Science & Applications)2022,11,7: | 4 |
| 6 | Crystal structure of plant PLDα1 reveals catalytic and regulatory mechanisms of eukaryotic phospholipase D显示文摘Phospholipase D(PLD)hydrolyzes the phosphodiester bond of glycerophospholipids and produces phosphatidic acid(PA),which acts as a second messenger in many living organisms.A large number of PLDs have been identified in eukaryotes,and are viewed as promising targets for drug design because these enzymes are known to be tightly regulated and to function in the pathophysiology of many human diseases.However,the underlying molecular mechanisms of catalysis and regulation of eukaryotic PLD remain elusive.Here,we determined the crystal structure of full-length plant PLDα1 in the apo state and in complex with PA.The structure shows that the N-terminal C2 domain hydrophobically interacts with the C-terminal catalytic domain that features two HKD motifs.Our analysis reveals the catalytic site,substrate-binding mechanism,and a new Ca2+-binding site that is required for the activation of PLD.In addition,we tested several efficient small-molecule inhibitors against PLDα1,and suggested a possible competitive inhibition mechanism according to structure-based docking analysis.This study explains many long-standing questions about PLDs and provides structural insights into PLD-targeted inhibitor/drug design. | Jianxu Li Fang Yu Hui Guo Renxue Xiong Wenjing Zhang Fangyuan He Minhua Zhang Peng Zhang | 2020 | Cell Research2020,30,1: | 3 |
| 7 | Development of a novel RNAi therapy:Engineered miR-31 exosomes promoted the healing of diabetic wounds显示文摘Rationale:Chronic wounds associated with diabetes exact a heavy burden on individuals and society and do not have a specific treatment.Exosome therapy is an extension of stem cell therapy,and RNA interference(RNAi)-based therapy is a type of advanced precision therapy.Based on the discovery of chronic wound-related genes in diabetes,we combined exosome therapy and RNAi therapy through an engineering approach for the treatment of diabetic chronic wounds.Methods:We combined exosome therapy and RNAi therapy to establish a precision therapy for diabetes-associated wounds via an engineered exosome approach.Results:First,chronic diabetic wounds express low levels of miR-31-5p compared with nondiabetic wounds,and an miR-31-5p mimic was shown to be effective in promoting the proliferation and migration of three wound-related cell types in vitro.Second,bioinformatics analysis,luciferase reporter assays and western blotting suggested that miR-31-5p promoted angiogenesis,fibrogenesis and reepithelization by inhibiting factor-inhibiting HIF-1(HIF1AN,also named FIH)and epithelial membrane protein-1(EMP-1).Third,engineered miR-31 exosomes were generated as a miR-31-5p RNAi therapeutic agent.In vivo,the engineered miR-31 exosomes promoted diabetic wound healing by enhancing angiogenesis,fibrogenesis and reepithelization.Conclusion:Engineered miR-31 exosomes are an ideal disease pathophysiology-initiated RNAi therapeutic agent for diabetic wounds. | Jinghuan Huang Muyu Yu Wenjing Yin Bo Liang Ang Li Jingfeng Li Xiaolin Li Shichang Zhao Fang Liu | 2021 | Bioactive Materials2021,6,9: | 3 |
| 8 | Non-suicidal self-injury in Shanghai inner bound middle school students显示文摘Background Non-suicidal self-injury (NSSI) behaviour is very common among adolescents. Its prevalence and behavioural characteristics may vary according to regional and cultural differences. Investigation of NSSI locations and diagnosis of adolescents with NSSI are relatively lacking in China. Aims The study objective was to determine the prevalence and features of NSSI among middle school students in Shanghai. Methods The participants were from grade 6 to 8 selected from three junior schools in Jing’an District. Consenting students completed the Ottawa Self-Injury Inventory to determine the prevalence and characteristics of NSSI. Those who indicated NSSI within the past month were administered the Mini-International Neuropsychiatric Interview for Children and Adolescents to assess for emotional disorders. Result The result shows 510 participants (21.7%;mean age 13.51 (0.97) years old;56.7% female) reported at least one instance of NSSI during the previous 12 months. NSSI was significantly more common in girls than boys (24.9% vs 18.5%;χ^2=14.03, p=0.00). Commonly reported reasons for NSSI were for internal and external emotion regulation (87.9%, 82.3%) and social influence (57.8%). Anxiety disorders were the most common (28.9%) disorder associated with NSSI. Conclusion The rate of NSSI of middle school students in Shanghai inner bound is similar to those reported in North American and European youth. It is essential that school mental health professionals are aware of how to manage NSSI within the school setting. | Fang Zhang Paula F Cloutier Hongmei Yang Wenjing Liu Wenhong Cheng Zeping Xiao | 2019 | General Psychiatry2019,32,4: | 3 |
| 9 | Swelling characteristics of Gaomiaozi bentonite and its prediction显示文摘Gaomiaozi(GMZ) bentonite has been chosen as a possible matrix material of buffers/backfills in the deep geological disposal to isolate the high-level radioactive waste(HLRW) in China.In the Gaomiaozi deposit area,calcium bentonite in the near surface zone and sodium bentonite in the deeper zone are observed.The swelling characteristics of GMZ sodium and calcium bentonites and their mixtures with sand wetted with distilled water were studied in the present work.The test results show that the relationship between the void ratio and swelling pressure of compacted GMZ bentonite-sand mixtures at full saturation is independent of the initial conditions such as the initial dry density and water content but dependent on the ratio of bentonite to sand.An empirical method was accordingly proposed allowing the prediction of the swelling deformation and swelling pressure with different initial densities and bentonite-sand ratios when in saturated conditions.Finally,the swelling capacities of GMZ Na-and Ca-bentonites and Kunigel Na-bentonite are compared. | De'an Sun Wenjing Sun Lei Fang | 2014 | Journal of Rock Mechanics and Geotechnical Engineering2014,6,2: | 3 |
| 10 | Soil-water characteristics of Gaomiaozi bentonite by vapour equilibrium technique显示文摘Soil-water characteristics of Gaomiaozi(GMZ)Ca-bentonite at high suctions(3–287MPa)are measured by vapour equilibrium technique.The soil-water retention curve(SWRC)of samples with the same initial compaction states is obtained in drying and wetting process.At high suctions,the hysteresis behaviour is not obvious in relationship between water content and suction,while the opposite holds between degree of saturation and suction.The suction variation can change its water retention behaviour and void ratio.Moreover,changes of void ratio can bring about changes in degree of saturation.Therefore,the total change in degree of saturation includes changes caused by suction and that by void ratio.In the space of degree of saturation and suction,the SWRC at constant void ratio shifts to the direction of higher suctions with decreasing void ratio.However,the relationship between water content and suction is less affected by changes of void ratio.The degree of saturation decreases approximately linearly with increasing void ratio at a constant suction.Moreover,the slope of the line decreases with increasing suction and they show an approximately linear relationship in semi-logarithmical scale.From this linear relationship,the variation of degree of saturation caused by the change in void ratio can be obtained.Correspondingly,SWRC at a constant void ratio can be determined from SWRC at different void ratios. | Wenjing Sun De'an Sun Lei Fang Shiqing Liu | 2014 | Journal of Rock Mechanics and Geotechnical Engineering2014,6,1: | 2 |
| 11 | The relationships among structure variables of larch forests in China显示文摘Background:Larch(Larix Mill.)forests are widely distributed in the upper parts of mountainous areas in China,playing vital roles in constructing mountain landscapes and maintaining mountain environments.Despite their importance,our knowledges on the large-scale patterns of structure characteristics and the relationships between different structure variables are unclear.In this paper,we investigated 155 plots from 11 natural larch forest types across the country to explore the biogeographic patterns of the structure characteristics and the allometric relationships between different structure variables for Chinese larch forests.Results:The structure characteristics were significantly different among larch forest types.For different larch forest types,the power function fits the relationships between tree height and diameter at breast height(DBH),average DBH and stem density,and taper and stem density well,but with different exponents among larch forest types.The power exponents of the allometric relationships between tree height and DBH for different larch forest types varied from 0.61 to 0.93(mean=0.86)by standard major axis regression(SMA),and from 0.51 to 0.78(mean=0.56)by ordinary least square regression(OLS).The 50%,75%and 95%quantile regression(QR)and OLS indicated that the average DBH and taper of the L.gmelinii forests,L.gmelinii var.principis-rupprechtii forests,and L.sibirica forests were significantly correlated with stem density.Conclusions:The relationship between tree height and DBH showed a power function relationship for all larch forest types in China,but with different exponents.Overall,stem density was negatively correlated with average DBH and taper.The Sect.Larix forests exhibited stand density effect.Our findings provide an important basis for recognizing the biogeographic patterns of structure factors and for the management of larch forests in China. | Wenjing Fang Qing Zhao Qiong Cai Anwar Eziz Guoping Chen Yuhao Feng Heng Zhang Jiangling Zhu Chengjun Ji Zhiyao Tang Jingyun Fang | 2020 | Forest Ecosystems2020,7,4: | 2 |
| 12 | Novel SFTSV Phylogeny Reveals New Reassortment Events and Migration Routes显示文摘Severe fever with thrombocytopenia syndrome virus(SFTSV),the causative agent of a febrile human disease,was first identified from central and eastern provinces in China,and later in Japan and South Korea.Hubei Province is one of the major SFTS epidemic areas in the central part of China.This study reported the isolation of 11 new SFTSV strains from patients in Hubei Province collected in 2017.Extensive phylogenetic analyses were conducted based on the complete coding sequences of SFTSV segments including the new strains.It was suggested that five different SFTSV genotypes were circulating in Hubei,and 15 reassortment patterns and migration pathways correlated with each genotype were identified,which was more than previously recognized.Hubei Province was more involved in the evolutionary events of SFTSV than that previously thought in which the evolutionary events of SFTSV were reported to be independent from those in other epidemic regions.Further divergence of SFTSV strains was suggested by pairwise comparison of SFTSV sequences from each genotype and sequence identity normalized to representative strain in genotype C1.Subsequently,amino acid variations specific for genotype(s),strain(s),or cluster(s)were inspected,which may be related to differential biological activity of SFTSV strains/genotypes.In conclusion,we analyzed the current status of SFTSV phylogeny in Hubei Province and discussed the possible events correlated to SFTSV evolution.It provided an in-depth insight into SFTSV evolution,raising concerns for the use of proper SFTSV strains in future studies. | Xiaoli Wu Mingyue Li Yanfang Zhang Boyun Liang Junming Shi Yaohui Fang Zhengyuan Su Mengmeng Li Wenjing Zhang Ling Xu Jun Wang Qiaoli Wu Shuang Tang Hualin Wang Tao Zhang Cheng Peng Xin Zheng Fei Deng Shu Shen | 2021 | Virologica Sinica2021,36,2: | 2 |
| 13 | Effects of Bamboo Fiber Length and Loading on Mechanical,Thermal and Pulverization Properties of Phenolic Foam Composites显示文摘In order to improve the mechanical properties and toughness of phenolic foams,a reinforcement method using two kinds of bamboo fibers was optimized with respect to the fiber contents.The compressive and flexural properties,thermal stability,friability and morphology of the phenolic foam composites were studied.The mechanical properties of the pristine foam and composites were evaluated by measuring the compressive strength.The results showed that the greatest mechanical properties were achieved by incorporating 2.5wt%of the reinforcement,and the compressive and flexural strengths of the two composites increased by 26.21%and 24.35%,respectively,compared with that of the pristine foam.The results of thermogravimetric testing demonstrated that the addition of bamboo fiber imparted better thermal stability to the phenolic foam,which was mainly attributed to the higher initial thermal decomposition temperature of the bamboo fiber.However,the influences of both reinforcements on the thermal stability of the material were negligible.The incorporation of bamboo fiber decreased the friability of the phenolic foam.Furthermore,the reduction in friability of the foam composites with longer lengths were higher than that in foams with shorter bamboo fibers.Moreover,the morphology and cell sizes of the fiber-reinforced phenolic foams were analyzed by scanning electron microscopy,the results indicated strong bonding between the fibers and phenolic matrix,and the incorporation of the bamboo fibers into the foam resulted in increased cell size of the material.Finally,the thermal conductivity and flame resistance of the phenolic foams reinforced by the bamboo fibers were also measured. | Qiheng TANG Lu FANG Wenjing GUO | 2019 | Journal of Bioresources and Bioproducts2019,4,1: | 1 |
| 14 | Organic-inorganic hybrid hole transport layers with SnS doping boost the performance of perovskite solar cells显示文摘Perovskite solar cells(PSCs) have demonstrated excellent photovoltaic performance which currently rival the long-standing silicon solar cells’ efficiency. However, the relatively poor device operational stability of PSCs still limits their future commercialization. Binary sulfide is a category of materials with promising optoelectrical properties, which shows the potential to improve both the efficiency and stability of PSCs.Here we demonstrate that the inorganic tin monosulfide(Sn S) can be an efficient dopant in 2,2’,7,7’-tet rakis(N,N-di-p-methoxy-phenylamine)-9,9’-spirobifluorene(spiro-OMe TAD) to form a composite hole transport layer(HTL) for PSCs. Sn S nanoparticles(NPs) synthesized through a simple chemical precipitation method exhibit good crystallization and suitable band matching with the perovskites. The introduction of Sn S NPs in Spiro-OMTAD HTLs enhanced charge extraction, reduced trap state density, and shallowed trap state energy level of the devices based on the composite HTLs. Therefore, the resulting solar cells employing Sn S-doped spiro-OMe TAD HTLs delivered an improved stabilized power output efficiency of 21.75% as well as enhanced long-term stability and operational stability. Our results provide a simple method to modify the conventional spiro-OMe TAD and obtain PSCs with both high efficiency and good stability. | Xiaolu Zheng Haibing Wang Feihong Ye Cong Chen Weijun Ke Wenjing Zhang Chuanxin He Yanlong Tai Guojia Fang | 2022 | Journal of Energy Chemistry2022,31,5: | 1 |
| 15 | TNF-α promotes early atherosclerosis by increasing transcytosis of LDL across endothelial cells: Crosstalk between NF-κB and PPAR-γ显示文摘 | Youzhi Zhang Xiaoyan Yang Fang Bian Pinhui Wu Shasha Xing Gao Xu Wenjing Li Jiangyang Chi Changhan Ouyang Tao Zheng Dan Wu Yonghui Zhang Yongsheng Li Si Jin | 2014 | Journal of Molecular and Cellular Cardiology2014,,: | 1 |
| 16 | Recent progress in two-photon small molecule fluorescent probes for enzymes显示文摘Enzymes are macromolecular biological catalysts which can accelerate chemical reactions in living organisms. Almost all the physiological metabolism activities in the cell need enzymes to sustain life via rapid catalysis. Currently, medical research has proved that abnormal enzyme activity is associated with numerous diseases, such as Parkinson’s disease(PD), Alzheimer’s disease(AD) and cancers. On the other hand, early diagnosis of those diseases is of great significance to improve the survival rate and cure rate.In the current diagnostic tools, two-photon fluorescent probes(TPFPs) are developing rapidly due to their unique advantages, such as higher spatial resolution, deeper imaging depth, and lower biotoxicity.Therefore, the design and synthesis of two-photon(TP) small molecule enzymatic probes have broad prospects for early diagnosis and treatment of diseases. As of now, scientists have developed many TP small molecule enzymatic probes. This review aims to summarize the TP small molecule enzymatic probes and expound the reaction mechanism. | Ding Chen Wenjing Qin Haixiao Fang Lan Wang Bo Peng Lin Li Wei Huang | 2019 | Chinese Chemical Letters2019,30,10: | 1 |
| 17 | Removal of lead (II) from aqueous solution by a new biosorption material by immobilizing Cyanex272 in cornstalks显示文摘 | Wenjing Shao Lihua Chen Lili Lü Fang Luo | 2010 | Desalination2010,,1: | 1 |
| 18 | Mutation profiling of 16 candidate genes in de novo acute myeloid leukemia patients显示文摘This retrospective analysis aimed to investigate the mutation profile of 16 common mutated genes in de novo acute myeloid leukemia (AML) patients. A total of 259 patients who were diagnosed of de novo AML were enrolled in this study. Mutation profiling of 16 candidate genes were performed in bone marrow samples by using Sanger sequencing. We identified at least 1 mutation in 199 of the 259 samples (76.8%), and 2 or more mutations in 31.7% of samples. FLT3-ITD was the most common mutated gene (16.2%, 42/259), followed by CEBPA (15.1%, 39/259), NRAS (14.7%, 38/259), and NPM1 (13.5%, 35/259). Concurrence was observed in 97.1% of the NPM1 mutated cases and in 29.6% of the double mutated CEBPA cases. Distinct patterns of co-occurrence were observed for different hotspot mutations within the IDH2 gene: R140 mutations were associated with NPM1 and/or FLT3-ITD mutations, whereas R172 mutations co-occurred with DNMT3A mutations only. Concurrence was also observed in 86.6% of epigenetic regulation genes, most of which co-occurred with NPM1 mutations. The results showed certain rules in the mutation profiling and concurrence of AML patients, which was related to the function classification of genes. Defining the mutation spectrum and mutation pattern of AML will contribute to the comprehensive assessment of patients and identification of new therapeutic targets. | Yang Zhang Fang Wang Xue Chen Wenjing Liu Jiancheng Fang Mingyu Wang Wen Teng Panxiang Cao Hongxing Liu | 2019 | Frontiers of Medicine2019,13,2: | 1 |
| 19 | Preparation and characterization of wood-plastic plywood bonded with high density polyethylene film显示文摘 | Fang Lu Chang Liang Guo Wenjing | 2013 | European Journal of Wood and Wood Products2013,71,6: | 1 |
| 20 | The effect of clinical-grade retinal pigment epithelium derived from human embryonic stem cells using different transplantation strategies显示文摘Dear Editor, Many forms of sight-threatening diseases, including retinitis pigmentosa (RP) and age-related macular degeneration (AMD), are caused by the dysfunction, degeneration and loss of the retinal pigment epithelium (RPE)(Strauss, 2005). RPE cell transplantation may potentially recover or halt disease progression, in which human embryonic stem cells (hESCs) could serve as an unlimited donor source for RPE differentiation, and a few clinical trials have shown the safety and effective of transplantation of hESCs-derived RPE (hESC-RPE) for AMD patients (Schwartz et al., 2012;Schwartz etal., 2015;Song etal., 2015;da Cruz et al., 2018;Kashani et al., 2018;Liu et al., 2018). | Lei Wang Wei Wu Qi Gu Zengping Liu Qiyou Li Zhongwen Li Jinhui Fang Wenjing Liu Jun Wu Ying Zhang Liu Wang Haiwei Xu Wei Li Baoyang Hu Qi Zhou Zhengqin Yin Jie Hao | 2019 | Protein & Cell2019,10,6: | 1 |