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| 1 | Recent Development of SOFC Metallic Interconnect显示文摘Interest in solid oxide fuel cells (SOFC) stems from their higher efficiencies and lower levels of emitted pollutants, compared to traditional power production methods. Interconnects are a critical part in SOFC stacks, which connect cells in series electrically, and also separate air or oxygen at the cathode side from fuel at the anode side. Therefore, the requirements of interconnects are the most demanding, i.e., to maintain high electrical conductivity, good stability in both reducing and oxidizing atmospheres, and close coefficient of thermal expansion (CTE) match and good compatibility with other SOFC ceramic components. The paper reviewed the interconnect materials, and coatings for metallic interconnect materials. | Junwei Wu | 2010 | Journal of Materials Science & Technology2010，26，4： | 16 |
| 2 | Comparison of basic features and origins of oolitic shoal reservoirs between carbonate platform interior and platform margin locations in the Lower Triassic Feixianguan Formation of the Sichuan Basin,southwest China显示文摘The oolitic shoal reservoirs of the Lower Triassic Feixianguan Formation carbonates in the Sichuan Basin of southwest China are an important target for gas exploration in the basin.Their occurrence,like other cases worldwide,can be divided into two locations in general,i.e.,platform interior and platform margin locations.Their differences of reservoir features and origins,however,have not been investigated comprehensively due to different exploration degrees.This issue is addressed in this paper,to provide basic data and information for the basin's hydrocarbon exploration and for the study of carbonate platform sedimentology and reservoir geology worldwide.We compared the features of these two types of reservoirs in detail,including the depositional and diagenetic features,pore types and petrophysical features.Based on the comparison,the origin of the reservoirs was further discussed.It is shown that the reservoirs in platform interior and platform margin locations differ significantly.The interior carbonates were deposited in moderate to high energy settings and the dominant lithologic type was limestone,which was weakly compacted and intensely cemented and has undergone meteoric dissolution.Pore types include intragranular dissolution and moldic pores,with low porosities(<6%) and low permeabilities(<0.1 mD).By contrast,the platform margin carbonates were deposited in relatively high energy settings and mainly consisted of dolostones with some limestones.The rocks were strongly compacted but incompletely cemented.As a result,some primary intergranular pores were preserved.Both meteoric solution and burial solution have taken place.There are various types of pore spaces including intergranular and intercrystalline solution pores and residual intergranular pores.This type of reservoir generally has better petrophysical properties(>9% porosity and >0.1 mD permeability) and pore-throat structures than the interior reservoirs.These differences were influenced by both primary depositional features and secondary diagenesis.For the interior carbonate reservoirs,early meteoric dissolution,weak compaction and strong cementation are important controlling factors.By contrast,the factors controlling the formation of the margin carbonate reservoirs mainly include dolomitization,preservation of primary pores and burial dissolution. | Tan Xiucheng Zhao Luzi Luo Bing Jiang Xingfu Cao Jian Liu Hong Li Ling Wu Xingbo Nie Yong | 2012 | Petroleum Science2012，9，4： | 9 |
| 3 | The heterogeneity of islet autoantibodies and the progression of islet failure in type 1 diabetic patients显示文摘Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body Mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus. | Jin Liu Lingling Bian Li Ji Yang Chen Heng Chen Yong Gu Bingqin Ma Wei Gu Xinyu Xu Yun Shi Jian Wang Dalong Zhu Zilin Sun Jianhua Ma Hui Jin Xing Shi Heng Miao Bing Xin Yan Zhu Zhenwen Zhang Ruifang Bu Lan Xu Guangde Shi Wei Tang Wei Li Dongmei Zhou Jun Liang Xingbo Cheng Bimin Shi Jixiang Dong Ji Hu Chen Fang Shao Zhong Weinan Yu Weiping Lu Chenguang Wu Li Qian Jiancheng Yu Jialin Gao Xiaoqiang Fei Qingqing Zhang Xueqin Wang Shiwei Cui Jinluo Cheng Ning Xu Guofeng Wang Guoqing Han Chunrong Xu Yun Xie Minmin An Wei Zhang Zhixiao Wang Yun Cai Qi Fu Yu Fu Shuai Zheng Fan Yang Qingfang Hu Hao Dai Yu Jin Zheng Zhang Kuanfeng Xu Yifan Li Jie Shen Hongwen Zhou Wei He Xuqin Zheng Xiao Han Liping Yu Jinxiong She Mei Zhang Tao Yang | 2016 | Science China(Life Sciences)2016，59，9： | 5 |
| 4 | Synchrotron radiation X-ray powder diffraction techniques applied in hydrogen storage materials--A review显示文摘Synchrotron radiation is an advanced collimated light source with high intensity. It has particular advantages in structural characterization of materials on the atomic or molecular scale. Synchrotron radiation X-ray powder diffraction(SR-XRPD) has been successfully exploited to various areas of hydrogen storage materials. In the paper, we will give a brief introduction on hydrogen storage materials, X-ray powder diffraction(XRPD), and synchrotron radiation light source. The applications of ex situ and in situ time-resolved SR-XRPD in hydrogen storage materials, are reviewed in detail. Future trends and proposals in the applications of the advanced XRPD techniques in hydrogen storage materials are also discussed. | Honghui Cheng Chen Lu Jingjing Liu Yongke Yan Xingbo Han Huiming Jin Yu Wang Yi Liu Changle Wu | 2017 | Progress in Natural Science:Materials International2017，27，1： | 5 |
| 5 | Genome-wide association studies for inflorescence type and remontancy in Hydrangea macrophylla显示文摘Inflorescence type and remontancy are two valuable traits in bigleaf hydrangea(Hydrangea macrophylla L.)and both are recessively inherited.Molecular marker-assisted selection(MAS)can greatly reduce the time necessary to breed cultivars with desired traits.In this study,a genome-wide association study(GWAS)using 5803 single-nucleotide polymorphisms(SNPs)was performed using a panel of 82 bigleaf hydrangea cultivars.One SNP locus(Hy_CAPS_Inflo)associated with inflorescence type was identified with general linear model(GLM)and mixed linear model(MLM)methods that explained 65.5%and 36.1%of the phenotypic variations,respectively.Twenty-three SNPs associated with remontancy were detected in GLM whereas no SNP was detected in MLM.The SNP locus(Hy_CAPS_Inflo)was converted to a cleaved amplified polymorphic sequence(CAPS)marker that showed absolute identification accuracy(100%)of inflorescence type in a validation panel consisting of eighteen H.macrophylla cultivars.The SNP was investigated in 341 F1 progenies using genotyping by sequencing(GBS)and co-segregated with inflorescence type(χ^(2)=0.12;P=0.73).The SNP was subsequently used for breeding selection using kompetitive allele specific PCR(KASP)technology.Future directions for the use of genomics and MAS in hydrangea breeding improvement are discussed.The results presented in this study provide insights for further research on understanding genetic mechanisms behind inflorescence type and remontancy in H.macrophylla.The CAPS and KASP markers developed here will be immediately useful for applying MAS to accelerate breeding improvement in hydrangea. | Xingbo Wu Lisa W.Alexander | 2020 | Horticulture Research2020，7，1： | 3 |
| 6 | FlexPolh adaptive event polling for network-intensive applications显示文摘 | Xingbo WU Xiang LONG Lei WANG | 2016 | Frontiers of Computer Science2016，10，3： | 2 |
| 7 | Genetic analysis on 3'- terminal flanking region of uncoupling protein 3 in different pig breeds显示文摘The 3’-terminal flanking region of porcine uncoupling protein 3 (UCP3) was cloned, the sequence data revealed 15 nucleotide substitutions among Landrace and three Chinese native pig breeds named Neijiang, Minpig and Erhualian. The continuous 9 polymorphic sites were checked by PCR-RFLP, the results indicated that Erhualian had extraordinary gene frequency, presented most significant difference by x2 test compared with Landrace, Largewhite, Neijiang and Minpig respectively, significant level compared with Meishan; and Meishan also had significant difference compared with Landrace and Minpig respectively. These results can be concluded that Taihu pigs have special genetic characteristics among pig breeds. | FANG Meiying, ZHAO Xingbo, LI Ning & WU ChangxinCollege of Animal Science and Technology, China Agricultural University, Beijing 100094, China State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing 100094, China | 2002 | Chinese Science Bulletin2002，47，18： | 2 |
| 8 | ZIF-7@carbon composites as multifunctional interlayer for rapid and durable Li-S performance显示文摘The notorious'shuttle effect'of polysulfide during charge-discharge process induces grievous capacity fading,while the sluggish polysulfide conversion kinetics significantly hinders the development of practically viable lithium-sulfur(Li-S)batteries.In this study,a novel ZIF-7@carbon composite with ZIF-7 sheets vertically rooted on carbon cloth was developed as multifunctional interlayer to address these issues.The composite shows directional layered structure with outstanding compactness,and thus can provide massive active sites for accelerated redox reactions.The pore channels are perpendicular to the square surface,resulting in extremely high utilization of one-dimensional channels.Therefore,this structure can not only maintain the structural stability during the charge-discharge process by providing enough space for volume expansion,but also contribute to efficient exposure and utilization of active sites for the physical/chemical adsorption and catalytic conversion of polysulfide.As a result,Li-S batteries with the as-developed interlayer deliver a considerable areal capacity of 4.75 mAh cm^(-2) at an elevated sulfur loading of 5.5 mg cm^(-2),and an impressive cyclability with an extremely low capacity-fading rate of merely 0.04%per cycle over 500 cycles at 1 C. | Xingbo Wang Yan Zhao Feichao Wu Shuming Liu Zisheng Zhang Zhaoyang Tan Xiaohang Du Jingde Li | 2021 | Journal of Energy Chemistry2021，30，6： | 2 |
| 9 | Paleomagnetic constraints on Paleogene-Neogene rotation and paleo-stress in the northern Qaidam Basin显示文摘Knowing the rotation and paleo-stress history in Qaidam Basin is a fundamental parameter to quantify the mechanism of intracontinental deformation in Tibetan Plateau.However,few studies have been conducted on tectonic rotation and stress evolution over long timescales in the Qaidam Basin.Here,we report new magnetic declination and the anisotropy of magnetic susceptibility(AMS)from a~52–7 Ma sequence of fluvial and lacustrine sediments in the Dahonggou(DHG)section in the northern Qaidam Basin.The magnetic declination revealed that the northern Qaidam Basin underwent a clockwise rotation 25.1°±8.6°during~33–17 Ma,followed by a counterclockwise rotation 16.9°±6.8°during~17–13.5 Ma.The AMS results showed that the“earliest deformation”fabrics were interrupted by the“pencil structure”fabrics in the intervals of~52–45 and~21–15 Ma.The interruption,synchronous with the marked deceleration of the India-Asia convergence rate,indicates pulse of strong tectonic compressive stress.In addition,the AMS results documented a transition in stress direction from S-N to SW-NE at~15 Ma,suggesting a kinematic shift in the northeastern TP.Our constraints on the rotation and stress from the northern Qaidam Basin support the two-stage evolution of the Altyn Tagh Fault(ATF).The fast-rate slip motion on the ATF during the early Oligocene caused the clockwise rotation in the northern Qaidam Basin;the second stage with enhanced thrusting since the middle Miocene caused extensive crustal shortening and dispersive NW-trending folds and faults in the Qaidam Basin and the northeastern TP. | Ling SUN Junliang JI Bingshuai LI Xingbo LI Wujun WU Kexin ZHANG | 2022 | Science China Earth Sciences2022，65，12： | 1 |
| 10 | Pulse plating of Mn–Co alloys for SOFC interconnect applications显示文摘 | Junwei Wu Christopher D. Johnson Yinglu Jiang Randall S. Gemmen Xingbo Liu | 2008 | Electrochimica Acta2008，，2： | 1 |
| 11 | DC electrodeposition of Mn–Co alloys on stainless steels for SOFC interconnect application显示文摘 | Junwei Wu Yinglu Jiang Christopher Johnson Xingbo Liu | 2007 | Journal of Power Sources2007，，2： | 1 |
| 12 | Sequences and polymorphisms of exons 3 and 4 in porcine UCP_2 gene显示文摘Uncoupling proteins are mitochondrial membrane transporters, which regulate metabolic pathways of energy balance, and are associated with biological traits of animal body weight, resting metabolic rates and energy conversion. In this study, a region of the exons 3 and 4 of pig UCP2 gene was cloned and analyzed, and a new single nucleotide polymorphic site was detected by PCR-SSCP in five pig breeds. This newfound polymorphism results from a T to G substitution at the position of nucleotide 272, which is located in intron3. | FANG Meiying, LIU Chousheng, ZHAO Xingbo, LI Ning and WU Changxin(1. College of Animal Science and Technology, China Agricultural University, Beijing 100094, China 2. National Laboratory for A-gribiotechnology, China Agricultural University, Beijing 100094, China 3. Gansu Institute of Animal and Veterinary Science, Pingliang 744000, China) | 2002 | Progress in Natural Science:Materials International2002，12，7： | 1 |
| 13 | Targeting the“undruggable”cancer driver genes:Ras,myc,and tp53显示文摘The term“undruggable”is to describe molecules that are not targetable or at least hard to target pharmacologically.Unfortunately,some targets with potent oncogenic activity fall into this category,and currently little is known about how to solve this problem,which largely hampered drug research on human cancers.Ras,as one of the most common oncogenes,was previously considered“undruggable”,but in recent years,a few small molecules like Sotorasib(AMG-510)have emerged and proved their targeted anti-cancer effects.Further,myc,as one of the most studied oncogenes,and tp53,being the most common tumor suppressor genes,are both considered“undruggable”.Many attempts have been made to target these“undruggable”targets,but little progress has been made yet.This article summarizes the current progress of direct and indirect targeting approaches for ras,myc,two oncogenes,and tp53,a tumor suppressor gene.These are potential therapeutic targets but are considered“undruggable”.We conclude with some emerging research approaches like proteolysis targeting chimeras(PROTACs),cancer vaccines,and artificial intelligence(AI)-based drug discovery,which might provide new cues for cancer intervention.Therefore,this review sets out to clarify the current status of targeted anti-cancer drug research,and the insights gained from this review may be of assistance to learn from experience and find new ideas in developing new chemicals that directly target such“undruggable”molecules. | XINGBO WU DAN PAN SHOUYI TANG YINGQIANG SHEN | 2023 | BIOCELL2023，47，7： | 0 |
| 14 | Two haplotype-resolved genomes reveal important flower traits in bigleaf hydrangea(Hydrangea macrophylla)and insights into Asterid evolution显示文摘The Hydrangea genus belongs to the Hydrangeaceae family,in the Cornales order of flowering plants,which early diverged among the Asterids,and includes several species that are commonly used ornamental plants.Of them,Hydrangea macrophylla is one of the most valuable species in the nursery trade,yet few genomic resources are available for this crop or closely related Asterid species.Two high-quality haplotype-resolved reference genomes of hydrangea cultivars‘Veitchii’and‘Endless Summer’[highest quality at 2.22 gigabase pairs(Gb),396 contigs,N5022.8 megabase pairs(Mb)]were assembled and scaffolded into the expected 18 pseudochromosomes.Utilizing the newly developed high-quality reference genomes along with high-quality genomes of other related flowering plants,nuclear data were found to support a single divergence point in the Asterids clade where both the Cornales and Ericales diverged from the euasterids.Genetic mapping with an F1 hybrid population demonstrated the power of linkage mapping combined with the new genomic resources to identify the gene for inflorescence shape,CYP78A5 located on chromosome 4,and a novel gene,BAM3 located on chromosome 17,for causing double flower.Resources developed in this study will not only help to accelerate hydrangea genetic improvement but also contribute to understanding the largest group of flowering plants,the Asterids. | Xingbo Wu Sheron A.Simpson Ramey C.Youngblood Xiaofen FLiu Brian E.Scheffler Timothy A.Rinehart Lisa W.Alexander Amanda M.Hulse-Kemp | 2023 | Horticulture Research2023，10，12： | 0 |
| 15 | High-quality genome assembly and pan-genome studies facilitate genetic discovery in mung bean and its improvement显示文摘Mung bean is an economically important legume crop species that is used as a food,consumed as a vegetable,and used as an ingredient and even as a medicine.To explore the genomic diversity of mung bean,we assembled a high-quality reference genome(Vrad_JL7)that was479.35 Mb in size,with a contig N50 length of 10.34 Mb.A total of 40,125 protein-coding genes were annotated,representing96.9%of the genetic region.We also sequenced 217 accessions,mainly landraces and cultivars from China,and identified 2,229,343 high-quality single-nucleotide polymorphisms(SNPs).Population structure revealed that the Chinese accessions diverged into two groups and were distinct from non-Chinese lines.Genetic diversity analysis based on genomic data from 750 accessions in 23 countries supported the hypothesis that mung bean was first domesticated in south Asia and introduced to east Asia probably through the Silk Road.We constructed the first pan-genome of mung bean germplasm and assembled 287.73 Mb of non-reference sequences.Among the genes,83.1%were core genes and 16.9%were variable.Presence/absence variation(PAV)events of nine genes involved in the regulation of the photoperiodic flowering pathway were identified as being under selection during the adaptation process to promote early flowering in the spring.Genomewide association studies(GWASs)revealed 2,912 SNPs and 259 gene PAV events associated with 33 agronomic traits,including a SNP in the coding region of the SWEET10 homolog(jg24043)involved in crude starch content and a PAV event in a large fragment containing 11 genes for color-related traits.This high-quality reference genome and pan-genome will provide insights into mung bean breeding. | Changyou Liu Yan Wang Jianxiang Peng Baojie Fan Dongxu Xu Jing Wu Zhimin Cao Yunqing Gao Xueqing Wang Shutong Li Qiuzhu Su Zhixiao Zhang Shen Wang Xingbo Wu Qibing Shang Huiying Shi Yingchao Shen Bingbing Wang Jing Tian | 2022 | Plant Communications2022，3，6： | 0 |
| 16 | Adaptive hybrid force/position control for an industrial robot: theory and experiments显示文摘 | 马博军 Fang Yongchun Huang Xingbo Wu Shuihua | 2010 | High Technology Letters2010，16，2： | 0 |
| 17 | A Test Method for the Static/Moving State of Targets Applied to Airport Surface Surveillance MLAT System显示文摘Due to the particularity of its location algorithm,there are some unique difficulties and features regarding the test of target motion states of multilateration(MLAT)system for airport surface surveillance.This paper proposed a test method applicable for the airport surface surveillance MLAT system,which can effectively determine whether the target is static or moving at a certain speed.Via a normalized test statistic designed in the sliding data window,the proposed method not only eliminates the impact of geometry Dilution of precision(GDOP)effectively,but also transforms the test of different motion states into the test of different probability density functions.Meanwhile,by adjusting the size of the sliding window,it can fulfill different test performance requirements.The method was developed through strict theoretical extrapolation and performance analysis,and simulations results verified its correctness and effectiveness. | Huang Rongshun Peng We Li Jing Wu Honggang Li Xingbo | 2016 | Transactions of Nanjing University of Aeronautics and Astronautics2016，33，4： | 0 |
| 18 | Genetic differentiation of grain, fodder and pod vegetable type cowpeas (Vigna unguiculata L.) identified through single nucleotide polymorphisms from genotyping-by-sequencing显示文摘The species Vigna unguiculata L.(Walp),commonly known as cowpea,is a multi-purpose legume that has been selected into three subspecies that are divided into grain,fodder and pod(yardlong bean)types.However,genetic bases for distinctions are not well understood.The purpose of this study was to apply genotyping-by-sequencing(GBS)and current reference genome for V.unguiculata to distinguish three subspecies and identify signatures of divergence.The collection of 130 accessions included 128 cultivated from:1)ssp.cylindrica,fodder type;2)ssp.sesquipedalis,pod vegetable type;and 3)ssp.unguiculata,grain type.Two wilds genotypes from spp.dekindtiana and spp.pubescens,were used to anchor phylogeny.A total of 11,083 highly informative single nucleotide polymorphisms(SNPs)were discovered.Wild accessions showed distinct genetic fingerprints and were separated from cultivated subspecies.Principal component analysis showed closer relationship between ssp.unguiculata and ssp.cylindrica compared to ssp.sesquipedalis.Relative differentiation of cultivated subspecies(with Fixation Index,FST)indicated the existence of discrete signatures of selection.This work clarifies the population structure,phylogeny,and domestication of cultivated cowpeas.Furthermore,significant genetic differences between grain and pod vegetable types can provide valuable information for future breeding in three cowpea groups. | Xingbo Wu Andrés JCortés Matthew W.Blair | 2022 | Molecular Horticulture2022，2，1： | 0 |
| 19 | Identification of heat-induced proteomes in meiotic pollen mother cells of tomato'Maxifort'using single-cell-type tandem mass tag(TMT)proteomics显示文摘Heat stress(HS)poses a significant challenge to tomato production due to disruption of the reproductive organs,especially the male gametophytes.This study reports HS-induced proteome changes in meiotic pollen mother cells during early stages of anther development.Tomato(Solanum lycopersicum L.×S.habrochaites)'Maxifort'were grown in a heated polytunnel in Nashville,Tennessee,USA.Plants at flowering stage were subjected to heat treatment at 40±2℃ for 4 hr(11:00−15:00 HR);and the non-heat-treated control was at 30±2℃(day/night)at the same period of time for 10 d.The size of the flower buds containing meiotic pollen mother cells was determined based on the histology of DAPI stained cross section of anthers.Flower buds were embedded in optimal cutting temperature solutions(OCT)and then cut into sections of 20μm thickness.Sections containing meiotic pollen mother cells were collected using laser capture microdissection(LCM).A protein extraction procedure was optimized for the LCM collected pollen samples which yielded 25−30μg protein from 150,000−200,000 pollen cells.The heatinduced proteomes of meiotic pollen mother cells were quantified using tandem mass tag(TMT)quantitative proteomics analysis.Among the 6,343 quantified proteins,254 differentially expressed proteins(DEPs)showed significant differences in abundance level from heat treated to non-heat-treated control conditions.The heat-up-regulated-DEPs(96 proteins)include heat shock proteins,calreticulin and exocytosis(synaptobrevin)which are involved in protein folding/refolding/targeting/removal and secretion of aggregated and damaged proteins/peptides.The heat-down-regulated-DEPs(158 proteins)were involved in pathways of ubiquitin-mediated protein degradation,antioxidant mechanism,and metabolic processes of carbohydrates and lipids.Proteins affecting apoptotic programmed cell death and pollen mother cell meiotic activity were significantly changed under HS.The identified proteins and the affected biological processes could represent the major heat tolerance mechanisms during early developmental stages of male gametophyte when exposed to daily periods of above 40°C HS condition. | Hui Li Yaoguo Qin Xingbo Wu Joshua O'Hair Jesse Potts Suping Zhou Yong Yang Tara Fish Theodore W.Thannhauser | 2022 | Vegetable Research2022，2，1： | 0 |
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