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| 1 | Dissecting and Enhancing the Contributions of High-Molecular-Weight Glutenin Subunits to Dough Functionality and Bread Quality显示文摘Dear Editor, Seed storage proteins (SSPs) are frequently important determinants of crop quality traits (Shewry and Casey,1999).Dissecting and enhancing the genetic contributions of individual SSPs to their target traits are essential for effectively improving crop quality attributes.However,such a task is often difficult to accomplish,because SSPs are frequently expressed from multigene families and exhibit strong allelic variation.Consequently,detailed knowledge of the function of individual SSPs in crop quality trait is still limited.This scenario is well illustrated by high-molecular-weight glutenin subunits (HMWGSs),a complex family of SSPs that are involved in wheat enduse quality through affecting dough functionality (Békés,2012;Rasheed et al.,2014). | Yiwen Li Xuefi An Ran Yang Xiaomin Guo Guidong Yue Renchun Fan Bin Li Zhensheng Li Kunpu Zhang Zhenying Dong Luyan Zhang Jiankang Wang Xu Jia Hong-Qing Ling Aimin Zhang Xiangqi Zhang Daowen Wang | 2015 | Molecular Plant2015，8，2： | 9 |
| 2 | Internal failure of anode materials for lithium batteriesd——A critical review显示文摘Prevention of mechanical and finally electrochemical failures of lithium batteries is a critical aspect to be considered during their design and performance, especially for those with high specific capacities. Internal failure is observed as one of the most serious factors, including loss of electrode materials, structure deformation and dendrite growth. It usually incubates from atomic/molecular level and progressively aggravates along with lithiation. Understanding the internal failure is of great importance for developing solutions of failure prevention and advanced anode materials. In this research, different internal failure processes of anode materials for lithium batteries are discussed. The progress on observation technologies of the anode failure is further summarized in order to understand their mechanisms of internal failure. On top of them, this review aims to summarize innovative methods to investigate the anode failure mechanisms and to gain new insights to develop advanced and stable anodes for lithium batteries. | Xiangqi Meng Yaolin Xu Hongbin Cao Xiao Lin Pengge Ning Yi Zhang Yaiza Gonzalez Garcia Zhi Sun | 2020 | Green Energy & Environment2020，5，1： | 5 |
| 3 | Emerging roles for PlWl proteins in cancer显示文摘 | Yi Tan Lianyong Liu Mingan Liao Chaobao Zhang Shuanggang Hu Mei Zou Mingjun Gu Xiangqi Li | 2015 | Acta Biochimica et Biophysica Sinica2015，47，5： | 4 |
| 4 | Alteration of Terminal Heterochromatin and Chromosome Rearrangements in Derivatives of Wheat-Rye Hybrids显示文摘小麦黑麦增加和替换线和他们的自我子孙在 telomeric heterochromatin 和着丝点揭示了变化。而且,一个有丝分裂地不稳定的 dicentric 染色体和稳定的 multicentric 染色体在一根中国春天帝国的黑麦 3R 增加线的子孙被观察。一个不稳定的 multicentric 染色体在一根 6R/6D 替换线的子孙被发现。包括终端 heterochromatin 的运动和消失的终端 heterochromatin 的激烈的变化发生在小麦黑麦增加线 3R,和 5RS ditelosomic 增加线的子孙。高度稳定的 minichromosomes 在一根 monosomic 4R 增加线,一根 ditelosomic 5RS 增加线和一根 6R/6D 替换线的子孙被观察。有或没有为 telomeric DNA (TTTAGGG ) n 的 FISH 信号, Minichromosomes 源于一根 monosomic 4R 增加线对下一代稳定、能递送。结果显示着丝点和终端 heterochromatin 能深刻地在小麦黑麦混血儿衍生物被改变。 | Shulan Fu Zhenling Lv Xiang Guo Xiangqi Zhang Fangpu Han | 2013 | Journal of Genetics and Genomics2013，40，8： | 3 |
| 5 | New member of the guanosine triphosphatase activating protein family in the human epididymis显示文摘尽管没有差距在 epididymis 被探索了,在精子发生上激活蛋白质(差距) 的海鸟粪正弦 triphosphatase 的效果多年被学习了,为精子成熟的一个必要机关。在这研究,一个新差距成员,指定了为 MacGAP,在人的 epididymis 被克隆。有 70 kDa 和港口的一种通常认为的尺寸的 618 氨基酸的 Mac 差距 geneencodesaprotein 保存 RhoGAP 领域。MacGAP 的 N 终端和 C 终端肽被表示,他们的相应的反时代被准备。对 N 终端肽的反时代能检测象 0.3 ng 一样低的抗原,并且它的特性也被证实。然而,因为它的低敏感,对 C 终端肽的反时代没能检测它的抗原。Immunohistochemistry 证明 MacGAP 蛋白质依赖于 epididymis 并且有一个区域特定的表示模式,与在上皮的房间在头区域的基础节的高表示。结果在精子成熟为差距的生物效果的进一步的解释创造了一个基础。 | Xiangqi Li Qiang Liu Shigui Liu Jinsong Zhang Yonglian Zhang | 2008 | Acta Biochimica et Biophysica Sinica2008，40，10： | 3 |
| 6 | The spatiotemporal expression changes of 16 epididymis-specific genes induced by testosterone, heat, and combination treatment in cynomolgus monkey显示文摘包含阴囊的温暖的处理的试验性的不孕模型,睾丸激素植入,并且联合二被开发证实联合处理在 cynomolgus 在细菌房间 apoptosis 上导致的一个 synergistic 行动猴子睾丸。用这个模型, 16 的时间空间的表示变化报导了或在 epididymis 的新奇基因被调查在 epididymal 基因上检验处理的效果。这被表明这些区域特定的基因,其中一些地区性没被修理,随着这些处理极大地变化了。这些 epididymal 基因的表示层次波动,并且大多数基因的表示在处理的结束回到了将近正常的水平。而且,源于联合处理的表示变化不比那些源于单个处理更重要。这建议联合处理在 epididymal 基因的表示上有一个对抗行动并且它的效果不是象二个单个处理的同样在 epididymis 上不利的。 | Xiangqi Li Qiang Liu Shigui Liu Xuesen Zhang Yixun Liu Yonglian Zhang | 2008 | Acta Biochimica et Biophysica Sinica2008，40，8： | 3 |
| 7 | Neck observation versus elective neck dissection in management of clinical T1/2N0 oral squamous cell carcinoma: a retrospective study of 232 patients显示文摘Objective: The management of early-stage(cT1/2N0) oral squamous cell carcinoma(OSCC) remains a controversial issue. The aim of this study was to compare the clinical outcomes of neck observation(OBS) and elective neck dissection(END) in treating patients with cT1/2N0 OSCC.Methods: A total of 232 patients with cT1/2N0 OSCC were included in this retrospective study. Of these patients, 181 were treated with END and 51 with OBS. The survival curves of 5-year overall survival(OS), diseasespecific survival(DSS), and recurrence-free survival(RFS) rates were plotted using the Kaplan-Meier method for each group, and compared using the Log-rank test.Results: There was no significant difference in 5-year OS and DSS rates between END and OBS groups(OS:89.0% vs. 88.2%, P=0.906; DSS: 92.3% vs. 92.2%, P=0.998). However, the END group had a higher 5-year RFS rate than the OBS group(90.1% vs. 76.5%, P=0.009). Patients with occult metastases in OBS group(7/51) had similar 5-year OS rate(57.1% vs. 64.1%, P=0.839) and DSS rate(71.4% vs. 74.4%, P=0.982) to those in END group(39/181). In the regional recurrence patients, the 5-year OS rate(57.1% vs. 11.1%, P=0.011) and DSS rate(71.4% vs. 22.2%, P=0.022) in OBS group(7/51) were higher than those in END group(9/181).Conclusions: The results indicated that OBS policy could obtain the same 5-year OS and DSS as END. Under close follow-up, OBS policy may be an available treatment option for patients with clinical T1/2N0 OSCC. | Xiangqi Liu Xiaomei Lao Lizhong Liang Sien Zhang Kan Li Guiqing Liao Yujie Liang | 2017 | Chinese Journal of Cancer Research2017，29，3： | 2 |
| 8 | Chromosome engineering of pollen wheat显示文摘Chromosome engineering of pollen wheat is the new procedure combining anther culture and chromosome engineering techniques. It could transfer useful alien genes into wheat varieties, enhancing genetic diversity for investigation of genetics and breeding. In the present study, two new procedures, at genome level and single chromosome level, were established.Compared with the classical chromosome engineering, the chromosome engineering of pollen wheat has the following main characters: ( ⅰ ) diversity of products, ( ⅱ ) rapid stability and (ⅲ) high efficiency of selection. Experiments indicated that chromosome engineering of pollen wheat is an efficient way for creating alien translocation line, especially non-Robertsonian translocation line. Meanwhile, using this procedure combined with comprehensive identifying methods, the investigation of useful genes and molecular markers on rye chromosomes 1R and 6R respectively has been done. The roles and relationships between chromosome engineering of pollen | Han Hu Xiangqi Zhang Wenjun Zhang Jiankang Jing Erming Wang Xianping Wang | 1999 | Chinese Science Bulletin1999，44，11： | 2 |
| 9 | Development, identification and utilization of introgression lines using Chinese endemic and synthetic wheat as donors显示文摘Chromosome segmental introgression lines(ILs)are an effective way to utilize germplasm resources in crops.To improve agronomic traits of wheat cultivar(Triticum aestivum) Shi 4185, four sets of ILs were developed. The donors were Chinese endemic subspecies accessions Yunnan wheat(T. aestivum ssp. yunnanense) YN3, Tibetan semiwild wheat(T. aestivum ssp. tibetanum) XZ-ZM19450, and Xinjiang wheat(T. aestivum ssp. petropavlovskyi) XJ5, and synthetic wheat HC-XM1620 derived from a cross between T. durum acc. D67.2/P66.270 with Aegilops tauschii acc. 218.Totals of 356, 366, 445 and 457 simple sequence repeat(SSR)markers were polymorphic between Shi 4185 and YN3, XZZM19450, XJ5 and HC-XM1620, respectively. In total, 991 ILs were identified, including 300 derived from YN3, covering 95%of the genome of Shi 4185, 218 from XZ-ZM19450(79%), 279 from XJ5(97%), and 194 from HC-ZX1620(84%). The sizes and locations of each introgression were determined from a consensus SSR linkage map. Using the ILs, 11 putative Resear quantitative trait loci(QTLs) were identified for plant height(PH), spike length(SL) and grain number per spike(GNS).Comparative analyses of 24 elite ILs with the parents revealed that the four donor parents could be important resources to improve wheat SL and GNS. Our work offers a case for utilizing endemic landraces for QTL mapping and improvement of wheat cultivars using introgression lines. | Liqing Gu Bo Wei Renchun Fan Xu Jia Xianping Wang Xiangqi Zhang | 2015 | Journal of Integrative Plant Biology2015，57，8： | 2 |
| 10 | Identification of new T1BL.1RS translocation lines derived from wheat (Triticum aestivum L. cultivar “Xiaoyan No. 6”) and rye hybridization显示文摘 | Jun Ji Zhiguo Wang Jiazhu Sun Junming Li Xiangqi Zhang Daowen Wang Aimin Zhang | 2008 | Acta Physiologiae Plantarum2008，，5： | 1 |
| 11 | Identification of new T1BL.1RS translocation lines derived from wheat (Triticum aestivum L. cultivar “Xiaoyan No. 6”) and rye hybridization显示文摘 | Jun Ji Zhiguo Wang Jiazhu Sun Junming Li Xiangqi Zhang Daowen Wang Aimin Zhang | 2008 | Acta Physiologiae Plantarum2008，，5： | 1 |
| 12 | Hydrothermal synthesis of nanostructures Bi12TiO20 and their photocatalytie activity on acid orange 7 under visible light 显示文摘 | Zhu Xiangqi Zhang Jinlong Chen Feng | 2010 | Chemosphere2010，78，11： | 1 |
| 13 | Development of Triticum aestivume——Leymus mollis Translocation Lines and Identification of Resistance to Stripe Rust显示文摘Wheat stripe rust,caused by Puccinia striiformis f.sp.tritici,is one of the most widely distributed and destructive fungal diseases worldwide.Since 1995,most Chinese wheat cultivars have lost their stripe rust resistance due to the subsequent emergence of the new races CYR30,CYR31,CYR32,and CYR33(Han et al.,2010).Therefore,it is necessary to seek effective resistance genes and develop new resistance germplasm for wheat resistance breeding. | Haoxun Li Renchun Fan Shulan Fu Bo Wei Shichang Xu Jing Feng Qi Zheng Xianping Wang Fangpu Han Xiangqi Zhang | 2015 | Journal of Genetics and Genomics2015，42，3： | 1 |
| 14 | Improve- ment of high-temperature oxidation resistance and strength in alumina-forming austenitic stainless steel显示文摘 | Xu Xiangqi Zhang Xiaofeng Chen Guoliang | 2011 | Mater Lett2011，65，2122： | 1 |
| 15 | Effect of silicon additions on the oxide scale formation of an alumina- forming austenitic alloy显示文摘 | Xu Xiangqi Zhang Xiaofeng Sun Xiaoyang | 2012 | Corros Sci2012，65，： | 1 |
| 16 | Hydrothermal synthesis of nanostructures Bi12TiO20 and their photocatalytic activity on acid orange under visible light显示文摘 | Xiangqi Zhu Jinlong Zhang Feng Chen | 2010 | Chemosphere2010，78，： | 1 |
| 17 | Magnetic logic inverter from crossed structures of defect-free graphene with large unsaturated room temperature negative magnetoresistance显示文摘Introducing defects into graphene has been widely utilized to realize the negative magnetoresistanee(MR)effect in graphene.However,the reported graphene negative MR exhibits only^10%under 10 T at room temperature to date,which extremely limits the resolution of future spintronics devices.Moreover,intentional defect introduction can also cause unintentional degradation in graphene's intrinsic properties.In this paper,we report a magnetic logic inverter based on a crossed structure of defect-free graphene,resulting in a substantial gain of 4.81 mV/T while exhibiting room temperature operation.This crossed structure of graphene shows large unsaturated room temperature negative MR with an enhancement of up to 1,000%at 9 T.A transition behavior between negative and positive MR is observed in this crossed structure and the transition temperature can be tuned by a ratio of the conductivity between in-plane and out-of-plane transport.Our results open an intriguing path for future two-dimensional spintronics device applications. | Chao Feng Junxiang Xiang Ping Liu Xiangqi Wang Jianlin Wang Guojing Hu Meng Huang Zhi Wang Zengming Zhang Yuan Liu Yalin Lu Bin Xiang | 2019 | Nano Research2019，12，10： | 1 |
| 18 | Roles manganese effects on the oxidation resistance of the alumina-forming austenitic steels at above 800 :C 显示文摘 | Xu Xiangqi Zhang Xiaofeng Lu Zhaoping | 2012 | Oxidat Metals2012，78，56： | 1 |
| 19 | Aldosterone may induce visfatin expression via the GR-ERK1/2 signal pathway in 3T3-L1 adipocytes显示文摘The main function of aldosterone is to regulate blood pressure and electrolytic balance;however,recent studies have also focused on the effect of aldosterone on glucose metabolism especially in adipose tissue.Aldosterone was found to inhibit insulin-induced glucose uptake in 3T3-L1 adipocytes [1] and aldosterone deficiency was found to prevent high-fat-feeding-induced hyperglycemia and adipocyte dysfunction in mice [2].Visfatin,an adipokine discovered by the team of Fukuhara,is mainly released by adipose tissue [3].Treatment of 3T3-L1 adipocytes and L6 myocytes with visfatin increased basal glucose uptake,and glucose release was suppressed in H4IIEC3 hepatocytes after visfatin treatment [3].It has also been suggested that visfatin may act as a proinflammatory cytokine [4] and produce chronic inflammation in adipocytes [5].Eyileten et al.[6] reported that treatment with angiotensin-converting enzyme inhibitor,which can reduce plasma aldosterone concentration,decreased circulating visfatin level in diabetic nephropathy patients.These findings suggest a possible interaction between the renin–angiotensin–aldosterone system(RAAS)and visfatin.Considering the important roles of aldosterone and visfatin and the association between RAAS and visfatin,we hypothesize that there may be a direct regulatory interaction between aldosterone and visfatin.To test this hypothesis,3T3-L1 adipocytes were used as the cell model and the expression of visfatin was measured by qRT-PCR and western blot analysis. | Junhua Ma Xuemei Zhao Jichen Zhang Fei Sun Jiancan Lu Hongling Zhu Mingjun Gu Jingnan Wang Xiangqi Li | 2019 | Acta Biochimica et Biophysica Sinica2019，51，3： | 1 |
| 20 | Collective and Individual Assessment of the Risk of Death from COVID-19 for the Elderly,2020–2022显示文摘Introduction:Coronavirus disease 2019(COVID-19)has had profound disruptions worldwide.For a population or individual,it is critical to assess the risk of death for making preventative decisions.Methods:In this study,clinical data from approximately 100 million cases were statistically analyzed.A software and an online assessment tool were developed in Python to evaluate the risk of mortality.Results:Our analysis revealed that 76.51%of COVID-19-related fatalities occurred among individuals aged over 65 years,with frailty-associated deaths accounting for more than 80%of these cases.Furthermore,over 80%of the reported deaths involved unvaccinated individuals.A notable overlap was observed between aging and frailty-associated deaths,both of which were connected to underlying health conditions.For those with at least two comorbidities,the proportion of frailty and the proportion of COVID-19-related death were both close to 75 percent.Subsequently,we established a formula to calculate the number of deaths,which was validated using data from twenty countries and regions.Using this formula,we developed and verified an intelligent software designed to predict the death risk for a given population.To facilitate rapid risk screening on an individual level,we also introduced a six-question online assessment tool.Conclusions:This study examined the impact of underlying diseases,frailty,age,and vaccination history on COVID-19-related mortality,resulting in a sophisticated software and a user-friendly online scale to assess mortality risk.These tools offer valuable assistance in informed decision-making. | Chaobao Zhang Hongzhi Wang Zilu Wen Zhijun Bao Xiangqi Li | 2023 | China CDC weekly2023，5，18： | 1 |
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