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| 1 | Stress-mediated p38 activation promotes somatic cell reprogramming显示文摘环境调停压力的改编在生活的进化起必要作用。细胞的改编机制通常包含染色质结构,抄写, mRNA 稳定性和翻译的规定,它最后在基因表示导致有效变化。全球 epigenetic 变化也涉及体的细胞的 reprogramming 进导致的 pluripotent 由定义因素的茎(iPS ) 细胞。这里,我们报导象 hyperosmosis 那样的那个环境压力不仅便于四调停因素的 reprogramming,而且提高二或一导致因素的 iPS 房间代。导致 Hyperosmosis 的 p38 激活在这个过程起一个关键作用。组成的活跃 p38 模仿 hyperosmosis 的积极效果,当主导的否定 p38 和 p38 禁止者堵住 hyperosmosis 的效果时。进一步的学习显示调停压力的 p38 激活可以由减少全球 DNA methylation 水平并且提高 pluripotency 基因的表示支持 reprogramming。我们的结果表明象 hyperosmosis 一样的简单环境应力怎么帮助经由细胞内部的发信号和 epigenetic 调整改变房间的命运。 | Xinxiu Xu Quan Wang Yuan Long Ru Zhang Xiaoyuan Wei Mingzhe Xing Haifeng Gu Xin Xie | 2013 | Cell Research2013，23，1： | 12 |
| 2 | Short-range ordering and its effects on mechanical properties of high-entropy alloys显示文摘In this letter,we briefly summarize experimental and theoretical findings of fo rmation and characterization of short-range orderings(SROs)as well as their effects on the defo rmation behavior of high-entropy alloys(HEAs).We show that existence of SROs is a common yet key structural feature of HEAs,and tuning the degree of SROs is an effective way for optimizing mechanical properties of HEAs.In additional,the challenges concerning about formation mechanism and characterization of SROs in HEAs are discussed,and future research activities in this regard are also proposed. | Yuan Wu Fei Zhang Xiaoyuan Yuan Hailong Huang Xiaocan Wen Yihan Wang Mengyuan Zhang Honghui Wu Xiongjun Liu Hui Wang Suihe Jiang Zhaoping Lu | 2021 | Journal of Materials Science & Technology2021，，3： | 8 |
| 3 | Effect of Yupingfeng granules on the skin barrier in atopic dermatitis mice models显示文摘OBJECTIVE: To investigate effect of Yupingfeng granules, prepared with Chinese Medicines, on the wound healing and on the expression of aquaporin3(AQP3) and the skin barrier in the animal models of atopic dermatitis(AD).METHODS: Acute skin lesions of AD models were prepared using 2,4-dinitrochlorobenzo(DNCB) in mice and animals were treated with either Yupingfeng granules or placebo for two weeks. Skin wound healing outcome was assessed by measuring skin thickness, weight(quality) of the skin, and trans-epidermal water loss(TEWL). Expression of AQP3 mRNA and protein was assessed by reverse transcriotion polymerase chain reaction(RT-PCR)and immunoblotting, respectively.RESULTS: Yupingfeng granule treatment resulted in significant acceleration of wound healing with63.64% efficiency, which was significantly higher than that of placebo granule treatment(31.82%,P < 0.01 by Wilcoxon Rank-sum test). Skin thickness, weight of the wounded skin, and TEWL were significantly higher in the AD models compared to that of normal animals. Treatment with Yupingfeng granules resulted in significant decrease in skin thickness [(937 ± 31) vs(360 ± 21) μm, P < 0.01],weight of the wounded skin [(42 ± 4) vs(24 ± 5)mg, P < 0.01], and TEWL [(30 ± 4) vs(13 ± 4) g·h^(-1)·m-2, P < 0.01]. Yupingfeng granules also significantly down-regulated mRNA and protein expression of AQP3 in the animal models.CONCLUSION: Our findings suggested that Yupingfeng granules could be used in AD treatment. | Sun Zhanxue Wang Jingjun Kong Yuhong Li Nan Jiang Xiaoyuan Cao Ting Jia Yuanning Zhang Yueyue Zhang Yisheng Cheng Jing | 2018 | Journal of Traditional Chinese Medicine2018，38，6： | 6 |
| 4 | Soil erosion affects variations of soil organic carbon and soil respiration along a slope in Northeast China显示文摘Background:Although soil erosion plays a key role in the carbon cycle,a holistic and mechanistic understanding of the soil erosion process within the cycle is still lacking.The aim of this study was therefore to improve our mechanistic understanding of soil organic carbon(SOC)and soil respiration dynamics through an experiment conducted in an eroding black soil farmland landscape in Northeast China.Results:The depositional profiles store 5.9 times more SOC than the eroding profiles and 3.3 times more SOC than the non-eroding profiles.A linear correlation between the SOC and 137Cs(Caesium-137)was observed in our study,suggesting that the SOC decreased with increased soil erosion.Furthermore,the fractions of intermediate C and the microaggregate C were lowest at the eroding position and highest at the depositional position.In the depositional topsoil,the input of labile materials plays a promotional role in soil respiration.Conversely,in the subsoil(i.e.,below 10 cm),the potential mineralization rates were lowest at the depositional position—due to effective stabilization by physical protection within soil microaggregates.The field results of soil surface respiration also suggest that the depositional topsoil SOC is prone to be mineralized and that SOC at this depositional context is stabilized at subsoil depth.In addition,the high water contents at the depositional position can limit the decomposition rates and stabilize the SOC at the same time.Conclusions:The findings from this study support that a majority of the SOC at footslope is stored within most of the soil profile(i.e.,below 10 cm)and submitted to long-term stabilization,and meanwhile support that the depositional profile emits more CO2 than the summit due to its high amount and quality of SOC. | Tong Li Haicheng Zhang Xiaoyuan Wang Shulan Cheng Huajun Fang Gang Liu Wenping Yuan | 2019 | Ecological Processes2019，8，1： | 4 |
| 5 | The critical role of Indian summer monsoon on the remote forcing between Indian and Northwest Pacific during El Nio decaying year显示文摘Recent studies have found a connection between Indian Ocean Basin Warming and the anomalous Northwest Pacific Anticyclone(ANPWA) during El Ni?o decaying year.This study focuses on the necessary condition for this connection by using observation and numerical simulation.The seasonal transition of the Indian Ocean sea surface wind is critical to the climatic effect of Indian Ocean Basin Warming.When the South Asian Summer Monsoon reaches its peak,the background wind becomes desirable for basin warming,which then affects the climate in the Northwest Pacific.Via the Kelvin waves and Ekman divergence,the wind anomalies exist in the lower atmosphere east of the Indian Ocean warm Sea Surface Temperature(SST) anomalies,and intensify and sustain the ANWPA throughout the El Nio decaying summer.This impact plays an important role in the inter-annual variability of the East Asian Summer Monsoon. | HU HaiBo HONG XiaoYuan ZHANG Yuan YANG XiuQun HE Jie | 2013 | Science China Earth Sciences2013，56，3： | 3 |
| 6 | Influences of Indian Ocean interannual variability on different stages of El Nio: A FOAM1.5 model approach显示文摘Both the tropical Indian and tropical Pacific Oceans are active atmosphere-ocean interactive regions with robust interannual variability, which also constitutes a linkage between the two basins in the mode of variability. Using a global atmosphereocean coupled model, we conducted two experiments(CTRL and PC) to explore the contributions of Indian Ocean interannual sea surface temperature(SST) modes to the occurrence of El Ni?o events. The results show that interannual variability of the SST in the Indian Ocean induces a rapid growth of El Ni?o events during the boreal autumn in an El Ni?o developing year. However, it weakens El Ni?o events or even promotes cold phase conversions in an El Ni?o decaying year. Therefore, the entire period of the El Ni?o is shortened by the interannual variations of the Indian Ocean SST. Specifically, during the El Ni?o developing years, the positive Indian Ocean Dipole(IOD) events force an anomalous Walker circulation, which then enhances the existing westerly wind anomalies over the west Pacific. This will cause a warmer El Ni?o event, with some modulations by ocean advection and oceanic Rossby and Kelvin waves. However, with the onset of the South Asian monsoon, the Indian Ocean Basin(IOB) warming SST anomalies excite low level easterly wind anomalies over the west tropical Pacific during the El Ni?o decaying years. As a result, the El Ni?o event is prompted to change from a warm phase to a cold phase. At the same time, an associated atmospheric anticyclone anomaly appears and leads to a decreasing precipitation anomaly over the northwest Pacific. In summary, with remote forcing in the atmospheric circulation, the IOD mode usually affects the El Ni?o during the developing years, whereas the IOB mode affects the El Ni?o during the decaying years. | HONG XiaoYuan HU HaiBo YANG XiuQun ZHANG Yuan LIU GuoQiang LIU Wei | 2014 | Science China Earth Sciences2014，57，11： | 2 |
| 7 | A NEW APPROACH TO HOLISTIC NITROGEN MANAGEMENT IN CHINA显示文摘Since the 1980s,the widespread use of N fertilizer has not only resulted in a strong increase in agricultural productivity but also caused a number of environmental problems,induced by excess reactive N emissions.A range of approaches to improve N management for increased agricultural production together with reduced environmental impacts has been proposed.The 4R principles(right product,right amount,right time and right place)for N fertilizer application have been essential for improving crop productivity and N use efficiency while reducing N losses.For example,site-specific N management(as part of 4R practice)reduced N fertilizer use by 32%and increased yield by 5%in China.However,it has not been enough to overcome the challenge of producing more food with reduced impact on the environment and health.This paper proposes a new framework of food-chainnitrogen-management(FCNM).This involves good N management including the recycling of organic manures,optimized crop and animal production and improved human diets,with the aim of maximizing resource use efficiency and minimizing environmental emissions.FCNM could meet future challenges for food demand,resource sustainability and environmental safety,key issues for green agricultural transformation in China and other countries. | Xuejun LIU Zhenling CUI Tianxiang HAO Lixing YUAN Ying ZHANG Baojing GU Wen XU Hao YING Weifeng ZHANG Tingyu LI Xiaoyuan YAN Keith GOULDING David KANTER Robert HOWARTH Carly STEVENS Jagdish LADHA Qianqian LI Lei LIU Wim DE VRIES Fusuo ZHANG | 2022 | Frontiers of Agricultural Science and Engineering2022，9，3： | 2 |
| 8 | Effect of ceria on copper/γ-alumina catalysts for carbon monoxide and n-hexane oxidation显示文摘Effectofceriaoncopper/γ-aluminacatalystsforcarbonmonoxideandn-hexaneoxidation￥JiangXiaoyuan;ZhouRenxian;YuanXianxin;ZhengXiao... | Jiang Xiaoyuan Zhou Renxian Yuan Xianxin Zheng Xiaoming Jin Songshou (Institute of Catalysis, Hangzhou University, Hangzhou 310028, China) | 1996 | Journal of Environmental Sciences1996，8，2： | 1 |
| 9 | Surface modification and electrochemical studies of spherical nickel hydroxide 显示文摘 | WANG Xiaoyuan YAN Jie YUAN Huatang | 1998 | Journal of Power Sources1998，72，2： | 1 |
| 10 | An Outbreak of SARS-CoV-2 Omicron Subvariant BA.2.76 in an Outdoor Park—Chongqing Municipality,China,August 2022显示文摘Summary What is already known about this topic?Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)Omicron subvariant has a stronger transmission capacity and faster transmission speed than the previous strain. | Li Qi Wenge Tang Ju Wang Yu Xiong Yi Yuan Baisong Li Lin Yang Tingting Li Lianjian Yang Xiaoyuan Su Qin Li Lijie Zhang | 2022 | China CDC weekly2022，4，46： | 1 |
| 11 | Genetic characterization of E2 gene of classical swine fever virus by restriction fragment length polymorphism and phylogenetic analysis显示文摘 | Ning Chen Dejiang Li Xuemei Yuan Xiaoliang Li Hongxia Hu Binglin Zhu Xiaoyuan Wan Weihuan Fang | 2010 | Virus Genes2010，，3： | 1 |
| 12 | Management of post-stroke neuropsychiatric disorders显示文摘Post-stroke neuropsychiatric(NP) disorders are common and have complex etiologies.Multiple factors such as lesion location, personality characteristics, socioeconomic status, pre-stroke psychiatric history, and family support are the determining factors in most cases. Although depression and anxiety are more common, emotional incontinence and catastrophic reactions are also frequently observed. Post-stroke depression(PSD)has been associated with an increased risk of stroke recurrence. Despite its serious consequences and high prevalence, PSD remains undetected and untreated. Treatment options of NP disorders depend on severity, presentation at the time of diagnosis, and patient cooperation, and include antidepressants, mood stabilizers, exercise therapy, psychotherapy, and even revascularization. The efficient management of NP disorders improves outcomes, quality of life, and survival rates in post-stroke patients. However,very few studies have identified definitive treatment for these patients; therefore, further research is required. | Ahsan Ali Khan Lukui Chen Guilong Zhang Xiaoyuan Guo Guojian Wu Hong Wang Yang You Yuchun Gu Yonggui Yuan | 2016 | Translational Neuroscience and Clinics2016，2，4： | 1 |
| 13 | Genetic characterization of E2 gene of classical swine fever virus by restriction fragment length polymorphism and phylogenetic analysis显示文摘 | Ning Chen Dejiang Li Xuemei Yuan Xiaoliang Li Hongxia Hu Binglin Zhu Xiaoyuan Wan Weihuan Fang | 2010 | Virus Genes2010，，3： | 1 |
| 14 | TALEs as double-edged swords in plant-pathogen interactions:Progress,challenges,and perspectives显示文摘Xanthomonas species colonize many host plants and cause huge losses worldwide.Transcription activator-like effectors(TALEs)are secreted by Xanthomonas and translocated into host cells to manipulate the expression of target genes,especially by Xanthomonas oryzae pv.oryzae and Xanthomonas oryzae pv.oryzicola,which cause bacterial blight and bacterial leaf streak,respectively,in rice.In this review,we summarize the progress of studies on the interaction between Xanthomonas and hosts,covering both rice and other plants.TALEs are not only key factors that make plants susceptible but are also essential components of plant resistance.Characterization of TALEs and TALE-like proteins has improved our understanding of TALE evolution and promoted the development of gene editing tools.In addition,the interactions between TALEs and hosts have also provided strategies and possibilities for genetic engineering in crop improvement. | Biaoming Zhang Xiaoyuan Han Wenya Yuan Haitao Zhang | 2022 | Plant Communications2022，3，3： | 0 |
| 15 | Implications on the origin of cosmic rays in light of 10 TV spectral softenings显示文摘Precise measurements of the energy spectra of cosmic rays(CRs)show various kinds of features deviating from single power-laws,which give very interesting and important implications on their origin and propagation.Previous measurements from a few balloon and space experiments indicate the existence of spectral softenings around 10 TV for protons(and probably also for Helium nuclei).Very recently,the DArk Matter Particle Explorer(DAMPE)measurement about the proton spectrum clearly reveals such a softening with a high significance.Here we study the implications of these new measurements,as well as the groundbased indirect measurements,on the origin of CRs.We find that a single component of CRs fails to fit the spectral softening and the air shower experiment data simultaneously.In the framework of multiple components,we discuss two possible scenarios,the multiple source population scenario and the background plus nearby source scenario.Both scenarios give reasonable fits to the wide-band data from TeV to 100 PeV energies.Considering the anisotropy observations,the nearby source model is favored. | Cliuan Yue Peng-Xiong Ma Qiang Yuan Yi-Zhong Fan Zhan-Fang Chen Ming-Yang Cui Hao-Ting Dai Tie-Kuang Dong Xiaoyuan Huang Wei Jiang Shi-Jun Lei Xiang Li Cheng-Ming Liu Hao Liu Yang Liu Chuan-Ning Luo Xu Pan Wen-Xi Peng Rui Qiao Yi-Feng Wei Li-Bo Wu Zhi-Hui Xu Zun-Lei Xu Guan-Wen Yuan Jing-Jing Zang Ya-Peng Zhang Yong-Jie Zhang Yun-Long Zhang | 2020 | Frontiers of physics2020，15，2： | 0 |
| 16 | Communication-Efficient Decision-Making of Digital Twin Assisted Internet of Vehicles: A Hierarchical Multi-Agent Reinforcement Learning Approach显示文摘The connected autonomous vehicle is considered an effective way to improve transport safety and efficiency.To overcome the limited sensing and computing capabilities of individual vehicles,we design a digital twin assisted decision-making framework for Internet of Vehicles,by leveraging the integration of communication,sensing and computing.In this framework,the digital twin entities residing on edge can effectively communicate and cooperate with each other to plan sub-targets for their respective vehicles,while the vehicles only need to achieve the sub-targets by generating a sequence of atomic actions.Furthermore,we propose a hierarchical multiagent reinforcement learning approach to implement the framework,which can be trained in an end-to-end way.In the proposed approach,the communication interval of digital twin entities could adapt to timevarying environment.Extensive experiments on driving decision-making have been performed in traffic junction scenarios of different difficulties.The experimental results show that the proposed approach can largely improve collaboration efficiency while reducing communication overhead. | Xiaoyuan Fu Quan Yuan Shifan Liu Baozhu Li Qi Qi Jingyu Wang | 2023 | China Communications2023，20，3： | 0 |
| 17 | Effects of trace elements on mechanical properties of the TiZrHfNb high-entropy alloy显示文摘Refractory high-entropy alloys have great potential to be utilized as high-temperature materials,and the repeatability and reproducibility of their mechanical properties are critical for practical applications.In this work,nevertheless,we found that the mechanical properties of the TiZrHfNb HEA greatly varied with the content of impurities in the samples even using high-purity raw materials.Specifically,the oxygen impurity is mainly responsible for the increment of the yield stress due to the strong interstitial hardening effect,whilst the ductility deterioration closely associates with the content of metalloid elements B,C,and Si.Our analysis reveals that the metalloid elements not only tend to segregate at grain boundaries but also enhance the aggregation of Zr and Ti.Such co-segregation induced the formation of strong(Zr,Ti)-metalloid bonds,resulting in grain boundary embrittlement and brittle fracture.Our current work demonstrates that the impurity contents in refractory HEAs need to be strictly controlled during production in order to improve their stability of mechanical performance. | Xiaoyuan Yuan Yuan Wu Meisa Zhou Xiongjun Liu Hui Wang Suihe Jiang Xiaobin Zhang Honghui Wu Xiaochun Liu Zipan Chen Xiangqi Xu Zhaoping Lu | 2023 | Journal of Materials Science & Technology2023，，21： | 0 |
| 18 | Photoluminescence from Si_based SiN_xO_y films显示文摘B++, C++, Si++, and As++ with dose of 5×10 16 cm -2 were implanted into SiN-xO-y films grown on crystalline silicon by plasma_enhanced chemical vapor deposition. The ion_implanted samples exhibit their photoluminescence with different intensities and different peak wavelengths after thermal annealing. Especially, the C++_implanted SiN-xO-y films show very intense photoluminescence at green_yellow color region. | Liangsheng Liao Xiaobing Liu Zuhong Xiong Shuai Yuan Xiaoyuan Hou | 1998 | Chinese Science Bulletin1998，43，2： | 0 |
| 19 | Scientometric analysis of physics (1979-2008):A quantitative description of scientific impact显示文摘Citations are a way to show how researchers build on existing research to further evolve research.The citation count is an indication of the influence of specific articles.The importance of citations means that it is valuable to analyze the articles that are cited the most.This research investigates highly-cited articles in physics (1979-2008) using citation data from the ISI Web of Science.In this study,1544205 articles were examined.The objective of the analysis was to identify and list the highly-productive countries,institutions,authors,and fields in physics.Based on the analysis,it was found that the USA is the world leader in physics,and Japan has maintained the highest growth rate in physics research since 1990.Furthermore,the research focus at Bell Labs and IBM has played important roles in physics.A striking fact is that the five most active authors are all Japanese,but the five most active institutions are all in the USA.In fact,only The University of Tokyo is ranked among the top 11 institutions,and only American authors have single-author articles ranked among the top 19 articles.The highest-impact articles are distributed across 25 subjects categories.Physics,Multidisciplinary has 424 articles,and is ranked at No.1 in total articles;followed by Physics,Condensed Matter.The study can provide science policy makers with a picture of innovation capability in this field and help them make better decisions.Hopefully,this study will stimulate useful discussion among scientists and research managers about future research directions. | ZHENG YanNing YUAN JunPeng PAN YunTao ZHAO XiaoYuan | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，1： | 0 |
| 20 | Revealing the role of local shear strain partition of transformable particles in a TRIP-reinforced bulk metallic glass composite via digital image correlation显示文摘The coupling effects of the metastable austenitic phase and the amorphous matrix in a transformation-induced plasticity(TRIP)-reinforced bulk metallic glass(BMG)composite under compressive loading were investigated by employing the digital image correlation(DIC)technique.The evolution of local strain field in the crystalline phase and the amorphous matrix was directly monitored,and the contribution from the phase transformation of the metastable austenitic phase was revealed.Local shear strain was found to be effectively consumed by the displacive phase transformation of the metastable austenitic phase,which relaxed the local strain/stress concentration at the interface and thus greatly enhanced the plasticity of the TRIP-reinforced BMG composites.Our current study sheds light on in-depth understanding of the underlying deformation mechanism and the interplay between the amorphous matrix and the metastable crystalline phase during deformation,which is helpful for design of advanced BMG composites with further improved properties. | Xiaoyuan Yuan Yuan Wu Xiongjun Liu Hui Wang Suihe Jiang Zhaoping Lü | 2022 | International Journal of Minerals,Metallurgy and Materials2022，29，4： | 0 |
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