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| 1 | Synthesis and Antitumor Activities of 1,3,4-Thiadiazole Derivatives Possessing Benzisoselenazolone Scaffold显示文摘 | ZHAO Jie XUAN Lina ZHAO Haichuan CHENG Ji FU Xiaoyun LI Sha JING Fen LIU Yuming CHEN Baoquan | 2014 | Chemical Research in Chinese Universities2014，30，5： | 2 |
| 2 | Comparison ofβ-Amyloid Plaque Labeling Methods:Antibody Staining,Gallyas Silver Staining,and Thioflavin-S Staining显示文摘Objective To evaluate senile plaque formation and compare the sensitivity of three differentβ-amyloid(Aβ)labeling methods(antibody staining,Gallyas silver staining,and thioflavin-S staining)to detect Aβdeposition.Methods APPswe/PSEN1dE9 transgenic mice(APP/PS1)of different ages were used to examine spatiotemporal changes in Aβplaque deposition.Antibody staining,Gallyas silver staining,and thioflavin-S staining were used to detect Aβplaque deposition in the same brain region of adjacent slices from model mice,and the results were compared.Results With aging,Aβplaques first appeared in the cortex and then the deposition increased throughout the whole brain.Significantly greater plaque deposition was detected by 6E10 antibody than that analyzed with Gallyas silver staining or thioflavin-S staining(P<0.05).Plaque deposition did not show significant difference between the APP/PS1 mice brains assayed with Gallyas silver staining and ones with thioflavin-S staining(P=0.0033).Conclusions The APP/PS1 mouse model of Alzheimer’s disease could mimick the progress of Aβplaques occurred in patients with Alzheimer’s disease.Antibody detection of Aβdeposition may be more sensitive than chemical staining methods. | Xinze Shi Xuan Wei Longze Sha Qi Xu | 2018 | Chinese Medical Sciences Journal2018，33，3： | 1 |
| 3 | Clinico-pathologieal_ association of Henoeh-Schoenlein purpura nephritis and IgA nephropathy in chil- dren显示文摘 | Mao S Xuan X Sha Y | 2015 | Int J Clin Exp Pathol2015，8，3： | 1 |
| 4 | Visible light photoelectrochemical responsiveness of self-organized nanoporous WO 3 films显示文摘 | Wenzhang Li Jie Li Xuan Wang Sha Luo Juan Xiao Qiyuan Chen | 2010 | Electrochimica Acta2010，，1： | 1 |
| 5 | Increased expression of forkhead box M1 protein is associated with poor prognosis in clear cell renal cell carcinoma显示文摘 | Xiao-Rong Wu Yong-Hui Chen Dong-Ming Liu Jian-Jun Sha Han-Qing Xuan Juan-Jie Bo Yi-Ran Huang | 2013 | Medical Oncology2013，，1： | 1 |
| 6 | Analysis of protein- protein interactions and proteomic profiles of normal human lenses显示文摘 | Yao Z Yu H Xuan D Sha Q Hu J Zhang J | 2010 | Curt Eye Res2010，35，7： | 1 |
| 7 | Increased expression of forkhead box M1 protein is associated with poor prognosis in clear cell renal cell carcinoma显示文摘 | Xiao-Rong Wu Yong-Hui Chen Dong-Ming Liu Jian-Jun Sha Han-Qing Xuan Juan-Jie Bo Yi-Ran Huang | 2013 | Medical Oncology2013，，1： | 1 |
| 8 | Online ultrasonic terminal for measuring pig backfat thickness显示文摘The measurement of pig backfat thickness(PBFT)has to stand up to challenges with the reliability,accuracy,and convenience.Acquiring PBFT timely and precisely from a finite distance is extremely necessary to improve the process of pig production and implement effective management.In an attempt to alleviate these problems,an online handheld terminal was designed with a new method based on ultrasonic technology for measuring PBFT during the process of pig breeding,which can overcome the difficulties encountered in other destructive means.The terminal comprised three main components:a main microcontroller unit(MCU)to measure PBFT,a RFID module to identify each pig and send data(e.g.identity,measurement time and PBFT)to a server via wireless transmission module,and an ultrasonic transducer to drive and receive signals between them.A measurement error within 0-1 mm was acquired through testing three groups of samples.Results indicated that this handheld terminal had a required accuracy and proved that the ultrasonic wave processing method can be deployed in a mobile terminal for PBFT measurement.It also provided a feasible nondestructive alternative to measure PBFT.Associated with information management software platform,this method may ultimately help pig production farmers measure the PBFT accurately and conveniently,and improve the pig production efficiency. | Ganghong Zhang Wanlin Gao Sha Tao Lina Yu Guofeng Zhang Xuan Luo | 2018 | International Journal of Agricultural and Biological Engineering2018，11，2： | 1 |
| 9 | Free-radical evolution and decay in cross-linked polytetrafluoroethylene irradiated by gamma-rays显示文摘Electron spin resonance techniques were employed to investigate the effects of the absorbed dose and post-irradiation conditions on the evolution and decay of free-radicals in cross-linked polytetrafluoroethylene(XPTFE),induced byγ-ray radiation.Chain-end free-radicals,chain alkyl free-radicals,and tertiary alkyl free-radicals were detected when XPTFE was irradiated under Ar atmosphere.The corresponding peroxy free-radicals were formed upon exposure of irradiated XPTFE to air;the freeradicals concentration first increased linearly with increasing absorbed dose and then gradually saturated.The free-radicals yield under air atmosphere was greater than that under Ar,and the peroxy free-radicals were preserved for a relatively long time when irradiated XPTFE was stored under air atmosphere.The chain alkyl free-radicals may be converted to chain end free-radicals byβ-scission,while chain end free-radicals are more sensitive to oxygen than chain alkyl free-radicals.When the annealing temperature was raised above the a-transition temperature of XPTFE,the decay of the free-radicals was greatly affected and accelerated by the motion of the molecules over the long range. | Fei-Xiang Sha Guo-Jun Cheng Zi-Yue Xuan Yang Liu Wei-Hua Liu Xiao-Dong Zhang Zhong-Feng Tang | 2022 | Nuclear Science and Techniques2022，33，5： | 0 |
| 10 | A Beam-Steering Broadband Microstrip Antenna with High Isolation显示文摘In this paper,a 4.2–7.2 GHz(52.6%)beam-steering microstrip antenna was proposed.The proposed antenna consists of three tapered slots and feeds.The three radiation directions of the antenna on the plane are independent of each other,and the three feeds correspond to the three radiation structures.Symmetry isolation trenches are introduced to improve isolation between different ports.Radiation pattern simulation and measurement show horizontal beam steering at the sampled frequencies of 4.2,5,6,and 7.2 GHz.The results shows that the overlapped beam of the three ports in the Eplane and H-plane can cover more than 200 degrees and 60 degrees,respectively.Apart from the capability of beamsteering,high isolation(more than 28 dB)of the proposed antenna in the operating band is obtained. | JIANG Zhaoneng SHA Yongxin NIE Liying XUAN Xiaofeng | 2023 | Chinese Journal of Electronics2023，32，2： | 0 |
| 11 | Enantioselective Allylic Amination of Morita-Baylis-Hillman Acetates Catalyzed by Chiral Thiourea-Phosphine显示文摘chiral 催化的 Morita-Baylis-Hillman 醋酸盐的 enantioselective allylic 胺化作用基于环己烷的 thiourea 磷化氢催化剂被调查。面对 20 mol% 导出松香的 thiourea 磷化氢 3j, chiral 胺在多达 88% 产量和多达 85% ee 被获得。 | Xuan Zhao Tianchen Kang Jie Shen Feng Sha Xinyan Wu | 2015 | Chinese Journal of Chemistry2015，33，12： | 0 |
| 12 | Improved simulation of winter wheat yield in North China Plain by using PRYM-Wheat integrated dry matter distribution coefficient显示文摘The accurate simulation of regional-scale winter wheat yield is important for national food security and the balance of grain supply and demand in China.Presently,most remote sensing process models use the“biomass×harvest index(HI)”method to simulate regional-scale winter wheat yield.However,spatiotemporal differences in HI contribute to inaccuracies in yield simulation at the regional scale.Time-series dry matter partition coefficients(Fr)can dynamically reflect the dry matter partition of winter wheat.In this study,Fr equations were fitted for each organ of winter wheat using site-scale data.These equations were then coupled into a process-based and remote sensingdriven crop yield model for wheat(PRYM-Wheat)to improve the regional simulation of winter wheat yield over the North China Plain(NCP).The improved PRYM-Wheat model integrated with the fitted Fr equations(PRYM-Wheat-Fr)was validated using data obtained from provincial yearbooks.A 3-year(2000-2002)averaged validation showed that PRYM-Wheat-Fr had a higher coefficient of determination(R^(2)=0.55)and lower root mean square error(RMSE=0.94 t ha^(-1))than PRYM-Wheat with a stable HI(abbreviated as PRYM-Wheat-HI),which had R^(2) and RMSE values of 0.30 and 1.62 t ha^(-1),respectively.The PRYM-Wheat-Fr model also performed better than PRYM-Wheat-HI for simulating yield in verification years(2013-2015).In conclusion,the PRYM-Wheat-Fr model exhibited a better accuracy than the original PRYM-Wheat model,making it a useful tool for the simulation of regional winter wheat yield. | Xuan Li Shaowen Wang Yifan Chen Danwen Zhang Shanshan Yang Jingwen Wang Jiahua Zhang Yun Bai Sha Zhang | 2024 | Journal of Integrative Agriculture2024，23，4： | 0 |
| 13 | Deciphering the placental abnormalities associated with somatic cell nuclear transfer at single-nucleus resolution显示文摘Dear Editor,The placenta connecting the fetus to the matermal uterus provides material exchange and an immune-tolerant environment for the embryo in all eutherian mammals(Shao et al.,2022).The representative mouse placenta displays a multilayered structure with distinct characteristics and functions,including the matermal decidua,junctional zone,and labyrinth layer(Marsh and Blelloch,2020).The decidua,which is thought to be derived from the matermal endometrium(and further undergoes decidualization),provides an anchor for fetal trophoblast invasion.The junctional zone predominantly contains spongiotrophoblasts(SpT),glycogen trophoblasts(GlyT),and trophoblast giant cells(TGCs).The labyrinth is the innermost two-layer structure,which mainly consists of syncytiotrophoblast cells(SynTI and SynTII),sinusoidal TGCs(S-TGCs),and fetal endothelial cells(Simmons and Cross,2005). | Liyuan Jiang Xin Wang Leyun Wang Sinan Ma Yali Ding Chao Liu Siqi Wang Xuan Sha Ying Zhang Zhikun Li Wei Li Guihai Feng Qi Zhou | 2023 | Protein & Cell2023，14，12： | 0 |
| 14 | Y-box protein-1 modulates circSPECC1 to promote glioma tumorigenesis via miR-615-5p/HIP1/AKT axis显示文摘Y-box binding protein-1(YB-1)is upregulated in glioma and plays an important role in its occurrence and drug resistance.However,the involved regulatory processes and downstream pathways are still unclear.Since various circular RNAs(circRNAs)and microRNAs(miRNAs)also play roles in the pathogenesis of glioma,we hypothesize that YB-1 may exert its function through a circRNA-miRNA-protein interaction network.In this study,we use the RNA binding protein immunoprecipitation assay and quantitative reverse transcription polymerase chain reaction to determine the circRNAs involved in the regulation of YB-1 and further elucidate their biological functions.The level of circSPECC1(hsa_circ_0000745)modulated by YB-1 is significantly upregulated in the U251 and U87 glioma cell lines.Downregulation of circSPECC1 markedly inhibits the proliferation and invasiveness of U251 and U87 cells by inducing apoptosis.Bioinformatics analysis reveals that miR-615-5p could interact with circSPECC1 and huntingtin-interacting protein-1(HIP-1).Then we determine the interactions between miR-615-5p,circSPECC1,and HIP1 using dual luciferase reporter system and pull-down assays.Mechanistic analysis indicates that the downregulation of circSPECC1 results in a decreased HIP1 expression.This study demonstrates that circSPECC1 modulated by YB-1 is increased in glioma cell lines.In addition,circSPECC1 promotes glioma growth through the upregulation of HIP1 by sponging miR-615-5p and targeting the HIP1/AKT pathway.This indicates that YB-1 and circSPECC1 may both be promising targets for glioma treatment. | Ping Lan Meihe Li Ying Wang Jingwen Wang Luyao Li Sha Zhang Xuan Zhang Caihong Ran Jin Zheng Huilin Gong | 2023 | Acta Biochimica et Biophysica Sinica2023，55，12： | 0 |
| 15 | Review of advanced road materials, structures, equipment, and detection technologies显示文摘As a vital and integral component of transportation infrastructure,pavement has a direct and tangible impact on socio-economic sustainability.In recent years,an influx of groundbreaking and state-of-the-art materials,structures,equipment,and detection technologies related to road engineering have continually and progressively emerged,reshaping the landscape of pavement systems.There is a pressing and growing need for a timely summarization of the current research status and a clear identification of future research directions in these advanced and evolving technologies.Therefore,Journal of Road Engineering has undertaken the significant initiative of introducing a comprehensive review paper with the overarching theme of“advanced road materials,structures,equipment,and detection technologies”.This extensive and insightful review meticulously gathers and synthesizes research findings from 39 distinguished scholars,all of whom are affiliated with 19 renowned universities or research institutions specializing in the diverse and multidimensional field of highway engineering.It covers the current state and anticipates future development directions in the four major and interconnected domains of road engineering:advanced road materials,advanced road structures and performance evaluation,advanced road construction equipment and technology,and advanced road detection and assessment technologies. | JRE Editorial Office Maria Chiara Cavalli De Chen Qian Chen Yu Chen Augusto Cannone Falchetto Mingjing Fang Hairong Gu Zhenqiang Han Zijian He Jing Hu Yue Huang Wei Jiang Xuan Li Chaochao Liu Pengfei Liu Quantao Liu Guoyang Lu Yuan Ma Lily Poulikakos Jinsong Qian Aimin Sha Liyan Shan Zheng Tong B.Shane Underwood Chao Wang Chaohui Wang Di Wang Haopeng Wang Xuebin Wang Chengwei Xing Xinxin Xu Min Ye Huanan Yu Huayang Yu Zhe Zeng You Zhan Fan Zhang Henglong Zhang Wenfeng Zhu | 2023 | Journal of Road Engineering2023，3，4： | 0 |
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