|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Optical vortices 30 years on:OAM manipulation from topological charge to multiple singularities显示文摘Thirty years ago,Coullet et al.proposed that a special optical field exists in laser cavities bearing some analogy with the superfluid vortex.Since then,optical vortices have been widely studied,inspired by the hydrodynamics sharing similar mathematics.Akin to a fluid vortex with a central flow singularity,an optical vortex beam has a phase singularity with a certain topological charge,giving rise to a hollow intensity distribution.Such a beam with helical phase fronts and orbital angular momentum reveals a subtle connection between macroscopic physical optics and microscopic quantum optics.These amazing properties provide a new understanding of a wide range of optical and physical phenomena,including twisting photons,spin–orbital interactions,Bose-Einstein condensates,etc.,while the associated technologies for manipulating optical vortices have become increasingly tunable and flexible.Hitherto,owing to these salient properties and optical manipulation technologies,tunable vortex beams have engendered tremendous advanced applications such as optical tweezers,high-order quantum entanglement,and nonlinear optics.This article reviews the recent progress in tunable vortex technologies along with their advanced applications. | Yijie Shen Xuejiao Wang Zhenwei Xie Changjun Min Xing Fu Qiang Liu Mali Gong Xiaocong Yuan | 2019 | Light(Science & Applications)2019，8，1： | 77 |
| 2 | Discovery of Triassic volcanic-sedimentary strata in the basement of Songliao Basin显示文摘In the Songliao Basin, the existence of lower Mesozoic strata remains a debatable issue. Previous studies indicated the absence of Triassic to Lower and Middle Jurassic strata in northeastern China because of uplift and erosion events associated with the return of geo-synclinal folds and orogenic movement during the Late Permian-Early Jurassic. To date, geochronological studies of intrusive and metamorphic rocks in the basement of the Songliao Basin have also confirmed Carboniferous, Permian, and Late Jurassic ages for the basement formations in general [1-4]. In the International Continental Scientific Drilling Project (ICDP) in the Songliao Basin, radiometric dating has been carried out for the entire drilling core of the SK-2 east borehole. As a result, we have discovered Triassic volcanic-sedimentary strata in the basement of the Songliao Basin. | Yongkang Yin Youfeng Gao Pujun Wang Xuejiao Qu Haibo Liu | 2019 | Science Bulletin2019，64，10： | 11 |
| 3 | Recent Advances in Tumor Microenvironment Hydrogen Peroxide-Responsive Materials for Cancer Photodynamic Therapy显示文摘Photodynamic therapy(PDT),as one of the noninvasive clinical cancer phototherapies,suffers from the key drawback associated with hypoxia at the tumor microenvironment(TME),which plays an important role in protecting tumor cells from damage caused by common treatments.High concentration of hydrogen peroxide(H2O2),one of the hallmarks of TME,has been recognized as a double-edged sword,posing both challenges,and opportunities for cancer therapy.The promising perspectives,strategies,and approaches for enhanced tumor therapies,including PDT,have been developed based on the fast advances in H2O2-enabled theranostic nanomedicine.In this review,we outline the latest advances in H2O2-responsive materials,including organic and inorganic materials for enhanced PDT.Finally,the challenges and opportunities for further research on H2O2-responsive anticancer agents are envisioned. | Nan Yang Wanyue Xiao Xuejiao Song Wenjun Wang Xiaochen Dong | 2020 | Nano-Micro Letters2020，12，1： | 11 |
| 4 | Aptamer-conjugated upconversion nanoprobes assisted by magnetic separation for effective isolation and sensitive detection of circulating tumor cells显示文摘 | Shuai Fang Chao Wang Jian Xiang Liang Cheng Xuejiao Song Ligeng Xu Rui Peng Zhuang Liu | 2014 | Nano Research2014，7，9： | 10 |
| 5 | A natural variation in Ribonuclease H-like gene underlies Rht8 to confer“Green Revolution”trait in wheat显示文摘Dear Editor,Introduction of gibberellin(GA)-insensitive Reduced height(Rht)genes,Rht-B1b and Rht-D1b,has resulted in the“Green Revolution”in modern wheat cultivars(Triticum aestivum)that has skyrocketed wheat grain yields worldwide since the 1960s(Peng et al.,1999;Velde et al.,2021).However,Rht-B1b/D1b also reduce coleoptiles,which is undesired in dryland regions where deep planting is essential for seedling establishment(Rebetzke et al.,1999,Rebetzke et al.,2001;Ellis et al.,2004). | Lingling Chai Mingming Xin Chaoqun Dong Zhaoyan Chen Huijie Zhai Junhong Zhuang Xuejiao Cheng Naijiao Wang Jia Geng Xiaobo Wang Ruolin Bian Yingyin Yao Weilong Guo Zhaorong Hu Huiru Peng Guihua Bai Qixin Sun Zhenqi Su Jie Liu Zhongfu Ni | 2022 | Molecular Plant2022，15，3： | 8 |
| 6 | Compositions and sources of organic acids in fine particles(PM_(2.5)) over the Pearl River Delta region, south China显示文摘Organic acids as important constituents of organic aerosols not only influence the aerosols' hygroscopic property, but also enhance the formation of new particles and secondary organic aerosols. This study reported organic acids including C14–C32fatty acids, C4–C9dicarboxylic acids and aromatic acids in PM2.5collected during winter 2009 at six typical urban, suburban and rural sites in the Pearl River Delta region. Averaged concentrations of C14–C32fatty acids, aromatic acids and C4– C9 dicarboxylic acids were 157, 72.5 and 50.7 ng/m3, respectively. They totally accounted for 1.7% of measured organic carbon. C20–C32fatty acids mainly deriving from higher plant wax showed the highest concentration at the upwind rural site with more vegetation around, while C14–C18fatty acids were more abundant at urban and suburban sites, and dicarboxylic acids and aromatic acids except 1,4-phthalic acid peaked at the downwind rural site. Succinic and azelaic acid were the most abundant among C4–C9dicarboxylic acids, and 1,2-phthalic and 1,4-phthalic acid were dominant aromatic acids. Dicarboxylic acids and aromatic acids exhibited significant mutual correlations except for 1,4-phthalic acid, which was probably primarily emitted from combustion of solid wastes containing polyethylene terephthalate plastics. Spatial patterns and correlations with typical source tracers suggested that C14–C32fatty acids were mainly primary while dicarboxylic and aromatic acids were largely secondary. Principal component analysis resolved six sources including biomass burning, natural higher plant wax, two mixed anthropogenic and two secondary sources; further multiple linear regression revealed their contributions to individual organic acids. It turned out that more than 70% of C14–C18fatty acids were attributed to anthropogenic sources, about 50%–85% of the C20–C32fatty acids were attributed to natural sources, 80%–95% of dicarboxylic acids and 1,2-phthalic acid were secondary in contrast with that 81% of 1,4-phthalic acid was primary. | Xiuying Zhao Xinming Wang Xiang Ding Quanfu He Zhou Zhang Tengyu Liu Xiaoxin Fu Bo Gao Yunpeng Wang Yanli Zhang Xuejiao Deng Dui Wu | 2014 | Journal of Environmental Sciences2014，26，1： | 6 |
| 7 | Local-scale drivers of multi-stemmed tree formation in Acer,in a temperate forest of Northeast China显示文摘Acer is an important genus in temperate forests in Northeast China.Individual Acer trees can re-sprout from the root collar and can occur in clonal units,either as a single-stemmed or multi-stemmed tree.However,the factors that induce multiple-stems in Acer remain only partly understood.In this study,we determined the relative importance of abiotic and biotic variables in driving the production of multiple-stems in this genus,within a 25-hm^2experimental forest dynamics plot in Changbaishan(CBS)temperate forest.We used generalized linear mixed models to perform analyses at two levels(community-and specieslevel).We found seven Acer species in total within the plot,where they form a key part of the forest community.Our results show that abiotic factors play a more important role in producing multi-stemmed trees at the community level in CBS.At the species level,the relative importance of different factors varied among species.Shrub species tended to have a higher frequency of multi-stemmed trees under stressful conditions,whereas tree species tended to have more multi-stemmed trees in more suitable habitat.Our results indicate that the relative importance of different factors influencing the frequency of multi-stemmed individuals in Acer differs at the community and species level in the temperate forest. | Ji Ye Zhanqing Hao Xugao Wang Xuejiao Bai Dingliang Xing Zuoqiang Yuan | 2014 | Chinese Science Bulletin2014，59，3： | 6 |
| 8 | Distribution of Microbial Populations and Their Relationship with Environmental Variables in the North Yellow Sea,China显示文摘In order to understand the large-scale spatial distribution characteristics of picoplankton,nanophytoplankton and virio-plankton and their relationship with environmental variables in coastal and offshore waters,flow cytometry(FCM) was used to ana-lyze microbial abundance of samples collected in summer from four depths at 36 stations in the North Yellow Sea(NYS).The data revealed spatial heterogeneity in microbial populations in the offshore and near-shore waters of the NYS during the summer.For the surface layer,picoeukaryotes were abundant in the near-shore waters,Synechococcus was abundant in the offshore areas,and bacte-rial and viral abundances were high in the near-shore waters around the Liaodong peninsula.In the near-shore waters,no significant vertical variation of picophytoplankton(0.2-2μm) abundance was found.However,the nanophytoplankton abundance was higher in the upper layers(from the surface to 10 m depth) than in the bottom layer.For the offshore waters,both pico-and nanophytoplankton(2-20μm) abundance decreased sharply with depth in the North Yellow Sea Cold Water Mass(NYSCWM).But,for the vertical dis-tribution of virus and bacteria abundance,no significant variation was observed in both near-shore and offshore waters.Autotrophic microbes were more sensitive to environmental change than heterotrophic microbes and viruses.Viruses showed a positive correla-tion with bacterial abundance,suggesting that the bacteriophage might be prominent for virioplankton(about 0.45μm) in summer in the NYS and that viral abundance might play an important role in microbial loop functions. | BAI Xiaoge WANG Min LIANG Yantao ZHANG Zhifeng WANG Fang JIANG Xuejiao | 2012 | Journal of Ocean University of China2012，11，1： | 5 |
| 9 | Unmanned aerial vehicle swarm mission reliability modeling and evaluation method oriented to systematic and networked mission显示文摘With the development of Unmanned Aerial Vehicle(UAV) system autonomy, network communication technology and group intelligence theory, mission execution in the form of a UAV swarm will be an important realization of future applications. Traditional single-UAV mission reliability modeling methods have been unable to meet the requirements of UAV swarm mission reliability modeling. Therefore, the UAV swarm mission reliability modeling and evaluation method is proposed. First, aimed at the interdependence among the multiple layers, a multi-layer network model of a UAV swarm is established. At the same time, based on the system having the following characteristics—using a mission chain to complete the mission and applying the connectivity of the mission network—the mission network model of a UAV swarm is established. Second, vulnerability and connectivity are selected as two indicators to reflect the reliability of the mission, and aimed at random attack and deliberate attack, vulnerability and connectivity evaluation methods are proposed. Finally, the validity and accuracy of the constructed model are verified through simulations,and the model and selected indicators can meet the reliability requirements of the UAV swarm mission. In this way, this study provides quantitative reference for UAV-swarm-related decisionmaking work and supports the development of UAV-swarm-related work. | Lizhi WANG Xuejiao ZHAO Yuan ZHANG Xiaohong WANG Tielin MA Xia GAO | 2021 | Chinese Journal of Aeronautics2021，34，2： | 5 |
| 10 | Source Contributions to PM2.5 under Unfavorable Weather Conditions in Guangzhou City,China显示文摘Historical haze episodes(2013–16) in Guangzhou were examined and classified according to synoptic weather systems.Four types of weather systems were found to be unfavorable, among which 'foreside of a cold front'(FC) and 'sea high pressure'(SP) were the most frequent(> 75% of the total). Targeted case studies were conducted based on an FC-affected event and an SP-affected event with the aim of understanding the characteristics of the contributions of source regions to fine particulate matter(PM_(2.5)) in Guangzhou. Four kinds of contributions—namely, emissions outside Guangdong Province(super-region), emissions from the Pearl River Delta region(PRD region), emissions from Guangzhou–Foshan–Shenzhen(GFS region), and emissions from Guangzhou(local)—were investigated using the Weather Research and Forecasting–Community Multiscale Air Quality model. The results showed that the source region contribution differed with different weather systems. SP was a stagnant weather condition, and the source region contribution ratio showed that the local region was a major contributor(37%), while the PRD region, GFS region and the super-region only contributed 8%, 2.8% and 7%, respectively, to PM_(2.5) concentrations. By contrast, FC favored regional transport. The super-region became noticeable,contributing 34.8%, while the local region decreased to 12%. A simple method was proposed to quantify the relative impact of meteorology and emissions. Meteorology had a 35% impact, compared with an impact of-18% for emissions, when comparing the FC-affected event with that of the SP. The results from this study can provide guidance to policymakers for the implementation of effective control strategies. | Nan WANG Zhenhao LING Xuejiao DENG Tao DENG Xiaopu LYU Tingyuan LI Xiaorong GAO Xi CHEN | 2018 | Advances in Atmospheric Sciences2018，35，9： | 5 |
| 11 | Novel resonant pressure sensor based on piezoresistive detection and symmetrical in-plane mode vibration显示文摘In this paper,a novel resonant pressure sensor is developed based on electrostatic excitation and piezoresistive detection.The measured pressure applied to the diaphragm will cause the resonant frequency shift of the resonator.The working mode stress–frequency theory of a double-ended tuning fork with an enhanced coupling beam is proposed,which is compatible with the simulation and experiment.A unique piezoresistive detection method based on small axially deformed beams with a resonant status is proposed,and other adjacent mode outputs are easily shielded.According to the structure design,high-vacuum wafer-level packaging with different doping in the anodic bonding interface is fabricated to ensure the high quality of the resonator.The pressure sensor chip is fabricated by dry/wet etching,high-temperature silicon bonding,ion implantation,and wafer-level anodic bonding.The results show that the fabricated sensor has a measuring sensitivity of~19 Hz/kPa and a nonlinearity of 0.02%full scale in the pressure range of 0–200 kPa at a full temperature range of−40 to 80°C.The sensor also shows a good quality factor>25,000,which demonstrates the good vacuum performance.Thus,the feasibility of the design is a commendable solution for high-accuracy pressure measurements. | Xiangguang Han Qi Mao Libo Zhao Xuejiao Li Li Wang Ping Yang Dejiang Lu Yonglu Wang Xin Yan Songli Wang Nan Zhu Zhuangde Jiang | 2020 | Microsystems & Nanoengineering2020，6，1： | 4 |
| 12 | Transportation Mode Identification with GPS Trajectory Data and GIS Information显示文摘Global Positioning System(GPS) trajectory data can be used to infer transportation modes at certain times and locations. Such data have important applications in many transportation research fields, for instance,to detect the movement mode of travelers, calculate traffic flow in an area, and predict the traffic flow at a certain time in the future. In this paper, we propose a novel method to infer transportation modes from GPS trajectory data and Geographic Information System(GIS) information. This method is based on feature extraction and machine learning classification algorithms. While using GIS information to improve inference accuracy, we ensure that the algorithm is simple and easy to use on mobile devices. Applied to GeoLife GPS trajectory dataset, our method achieves 91.1% accuracy while inferring transportation modes, such as walking, bike, bus, car, and subway, with random forest classification algorithm. GIS features in our method improved the overall accuracy by 2.5% while raising the recall of the bus and subway transportation mode categories by 3.4% and 18.5%. We believe that many algorithms used in detecting the transportation modes from GPS trajectory data that do not utilize GIS information can improve their inference accuracy by using our GIS features, with a slight increase in the consumption of data storage and computing resources. | Ji Li Xin Pei Xuejiao Wang Danya Yao Yi Zhang Yun Yue | 2021 | Tsinghua Science and Technology2021，26，4： | 4 |
| 13 | Ectopic expression of VRT-A2 underlies the origin of Triticum polonicum and Triticum petropavlovskyi with long outer glumes and grains显示文摘Polish wheat (Triticum polonicum) is a unique tetraploid wheat species characterized by an elongated outer glume. The genetic control of the long-glume trait by a single semi-dominant locus, P1 (from Polish wheat), was established more than 100 years ago, but the underlying causal gene and molecular nature remain elusive. Here, we report the isolation of VRT-A2, encoding an SVP-clade MADS-box transcription factor, as the P1 candidate gene. Genetic evidence suggests that in T. polonicum, a naturally occurring sequence rearrangement in the intron-1 region of VRT-A2 leads to ectopic expression of VRT-A2 in floral organs where the long-glume phenotype appears. Interestingly, we found that the intron-1 region is a key ON/OFF molecular switch for VRT-A2 expression, not only because it recruits transcriptional repressors, but also because it confers intron-mediated transcriptional enhancement. Genotypic analyses using wheat accessions indicated that the P1 locus is likely derived from a single natural mutation in tetraploid wheat, which was subsequently inherited by hexaploid T. petropavlovskyi. Taken together, our findings highlight the promoter-proximal intron variation as a molecular basis for phenotypic differentiation, and thus species formation in Triticum plants. | Jing Liu Zhaoyan Chen Zhihui Wang Zhaoheng Zhang Xiaoming Xie Zihao Wang Lingling Chai Long Song Xuejiao Cheng Man Feng Xiaobo Wang Yanhong Liu Zhaorong Hu Jiewen Xing Zhenqi Su Huiru Peng Mingming Xin Yingyin Yao Weilong Guo Qixin Sun Jie Liu Zhongfu Ni | 2021 | Molecular Plant2021，14，9： | 4 |
| 14 | Clinical Predictors of Functional Cure in Children 1–6 Years-old with Chronic Hepatitis B显示文摘Background and Aims:Hepatitis B surface antigen(HBsAg)clearance is significantly more common in children with chronic hepatitis B(CHB)than in adults;however,the possible influencing factors related to HBsAg loss have yet to be found.This study aimed to explore the efficacy of long-term interferon(IFN)αtherapy in treating children with CHB and analyzed the factors influencing functional cure after treatment.Methods:A total of 236 children aged 1–6 years and diagnosed with CHB via liver biopsy were included in the study,all receiving IFNαtreatment(IFNα-2b monotherapy,IFNα-2b followed by lamivudine[LAM]or IFNα-2b combined with LAM)and followed up for 144 weeks.A comprehensive analysis was conducted on clinical data,including biochemical items,serum markers of hepatitis B virus(HBV)and immunological indexes,and logistic regression analysis was used to screen the influencing factors related to HBsAg loss.Results:The cumulative loss rates of HBsAg were 79.5%,62.1%and 42.1%at 144 weeks after the start of treatment in the 1–3 years-old group,3–5 years-old group and 5–7 years-old group,respectively(p<0.05).IFNα-2b combined with LAM treatment displayed the highest HBsAg loss rates compared with monotherapy and sequential treatment(p=0.011).Younger baseline age and lower HBsAg levels were independent factors for the prediction of HBsAg loss(p<0.05).The baseline PreS1 and hepatitis B core antibody levels in the HBsAg loss group were lower than those in the HBsAg non-loss group.In addition,the PreS1 level was positively corelated with the level of HBsAg,HBV DNA and liver inflammation.Conclusions:Long-term treatment with IFNαwas effective in achieving HBsAg loss in CHB children aged 1–6 years-old.Age less than 3 years-old and lower HBsAg levels are independent predictors of functional cure in children with CHB. | Jing Pan Haiyan Wang Tiantian Yao Xuejiao Liao Hao Cheng Suthat Liangpunsakul Yan Wang Min Zhang Zheng Zhang | 2022 | Journal of Clinical and Translational Hepatology2022，10，3： | 3 |
| 15 | Confined interface engineering of self-supported Cu@N-doped graphene for electrocatalytic CO_(2) reduction with enhanced selectivity towards ethanol显示文摘Electroreduction of greenhouse gas CO_(2) into value-added fuels and chemicals provides a promising pathway to address the issues of energy crisis and environmental change.However,the regulations of the selectivity towards C2 product and the competing hydrogen evolution reaction(HER)are major challenges for CO_(2) reduction reaction(CO_(2)RR).Here,we develop an interface-enhanced strategy by depositing a thin layer of nitrogen-doped graphene(N-G)on a Cu foam surface(Cu-N-G)to selectively promote the ethanol pathway in CO_(2)RR.Compared to the undetectable ethanol selectivity of pure Cu and Cu@graphene(Cu-G),Cu-N-G has boosted the ethanol selectivity to 33.1%in total Faradic efficiency(FE)at−0.8 V vs.reversible hydrogen electrode(RHE).The experimental and density functional theory(DFT)results verify that the interconnected graphene coating can not only serve as the fast charge transport channel but also provide confined nanospace for mass transfer.The N doping can not only trigger the intrinsic interaction between N in N-G and CO_(2) molecule for enriching the local concentration of reactants but also promote the average valence state of Cu for C–C coupling pathways.The confinement effect at the interface of Cu-N-G can not only provide high adsorbed hydrogen(Had)coverage but also stabilize the key*HCCHOH intermediate towards ethanol pathway.The provided interface-enhanced strategy herein is expected to inspire the design of Cubased CO_(2)RR electrocatalysts towards multi-carbon products. | Dejin Zang Xuejiao JGao Leyun Li Yongge Wei Haiqing Wang | 2022 | Nano Research2022，15，10： | 3 |
| 16 | Self-supporting nanoporous gold-palladium overlayer bifunctional catalysts toward oxygen reduction and evolution reactions显示文摘氧减小反应(ORR ) 和氧进化反应(OER ) 是为能量变换 / 存储系统的关键过程,例如燃料房间,金属空气电池,并且水切开。然而,两反应被他们的懒惰动力学严重地限制,因此要求高度活跃、划算、持久的 electrocatalysts。此处,我们通过驾驶 dealloying 的 nanoporous 黄金(NPG ) 的表面 nanoengineering 开发新奇 bifunctional nanocatalysts。Pd overlayers 被取向附生的 layer-by-layer 生长精确扔到 NPG 系带表面上。更重要地,获得的 NPG-Pd overlayer nanocatalysts 展览显著地在碱的媒介向 ORR 和 OER 提高了 electrocatalytic 活动,对 stateof- 艺术 Pt/C 催化剂的 benchmarked。改进 electrocatalytic 性能被 NPG,从 Pd overlayers 的精确控制的提高的 Pd 利用效率,和变化的唯一的三维的 nanoarchitecture 在电子结构文饰,作为由密度揭示了功能的理论计算。 | Yan Wang Wei Huang Conghui Si Jie Zhang Xuejiao Yan Chuanhong Jin Yi Ding Zhonghua Zhang | 2016 | Nano Research2016，9，12： | 3 |
| 17 | Scaling effect of breakthrough character in porous media显示文摘Breakthrough phenomenon during fluids percolating through wet saturated porous layer is widely met in the study of heat and mass transfer in porous media. Breakthrough pressure (BP) is a characteristic pressure that indicates the intrinsic properties of seepage within porous media. Measuring results of BP for saturated narrow-sieved sand are reported here. The curve of BP varying with the height of porous layer was obtained. Experiment and analysis indicate that BP is independent of the height of particle packed layer if thick enough; however, when the height is less than a certain critical value, BP diminishes with the decrease of the height according to a universal scaling law. | Xuejiao Hu Jianhua Du Xiang Liu Buxuan Wang | 2001 | Chinese Science Bulletin2001，46，10： | 3 |
| 18 | China-UK-Tanzania Pilot Project on Malaria Control显示文摘The China-UK-Tanzania Pilot Project on Malaria Control supported by the China-UK Global Health Support Programme and funded by the UK Department for International Development(DFID)is the first pilot project of its kind for the Chinese government in Africa.The encouraging results of this pilot project demonstrated that the malaria burden could be reduced by 81%(1)when China’s experience with malaria control was shared in Tanzania through interactions between health officials from China and Tanzania. | Xuejiao Ma Shenning Lu Duoquan Wang Zhengbin Zhou Jun Feng He Yan Shang Xia Wei Ding Ning Xiao Xiao-nong Zhou | 2020 | China CDC weekly2020，2，42： | 2 |
| 19 | Modulation of Beta Oscillations for Implicit Motor Timing in Primate Sensorimotor Cortex during Movement Preparation显示文摘Motor timing is an important part of sensorimotor control. Previous studies have shown that beta oscillations embody the process of temporal perception in explicit timing tasks. In contrast, studies focusing on beta oscillations in implicit timing tasks are lacking. In this study, we set up an implicit motor timing task and found a modulation pattern of beta oscillations with temporal perception during movement preparation. We trained two macaques in a repetitive visually-guided reach-to-grasp task with different holding intervals. Spikes and local field potentials were recorded from microelectrode arrays in the primary motor cortex, primary somatosensory cortex, and posterior parietal cortex. We analyzed the association between beta oscillations and temporal interval in fixedduration experiments(500 ms as the Short Group and1500 ms as the Long Group) and random-duration experiments(500 ms to 1500 ms). The results showed that the peak beta frequencies in both experiments ranged from15 Hz to 25 Hz. The beta power was higher during the hold period than the movement(reach and grasp) period.Further, in the fixed-duration experiments, the mean poweras well as the maximum rate of change of beta power in the first 300 ms were higher in the Short Group than in the Long Group when aligned with the Center Hit event. In contrast, in the random-duration experiments, the corresponding values showed no statistical differences among groups. The peak latency of beta power was shorter in the Short Group than in the Long Group in the fixed-duration experiments, while no consistent modulation pattern was found in the random-duration experiments. These results indicate that beta oscillations can modulate with temporal interval in their power mode. The synchronization period of beta power could reflect the cognitive set maintaining working memory of the temporal structure and attention. | Hongji Sun Xuan Ma Liya Tang Jiuqi Han Yuwei Zhao Xuejiao Xu Lubin Wang Peng Zhang Luyao Chen Jin Zhou Changyong Wang | 2019 | Neuroscience Bulletin2019，35，5： | 2 |
| 20 | Generating Giant Membrane Vesicles from Live Cells with Preserved Cellular Properties显示文摘Biomimetic giant membrane vesicles,with size and lipid compositions comparable to cells,have been recognized as an attractive experimental alternative to living systems.Due to the similarity of their membrane structure to that of body cells,cell-derived giant plasma membrane vesicles have been used as a membrane model for studying lipid/protein behavior of plasma membranes.However,further application of biomimetic giant membrane vesicles has been hampered by the side-efects of chemical vesiculants and the utilization of osmotic bufer.We herein develop a facile strategy to derive giant membrane vesicles(GMVs)from mammalian cells in biofriendly medium with high yields.Tese GMVs preserve membrane properties and adaptability for surface modifcation and encapsulation of exogenous molecules,which would facilitate their potential biological applications.Moreover,by loading GMVs with therapeutic drugs,GMVs could be employed for drug transport to tumor cells,which represents another step forward in the biomedical application of giant membrane vesicles.Tis study highlights biocompatible GMVs with biomimicking membrane surface properties and adaptability as an ideal platform for drug delivery strategies with potential clinical applications. | Qiaoling Liu Cheng Bi Jiangling Li Xuejiao Liu Ruizi Peng Cheng Jin Yang Sun Yifan Lyu Hui Liu Huijing Wang Can Luo Weihong Tan | 2019 | Research2019，，1： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员