|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A feasible strategy for focal cerebral ischemiareperfusion injury: remote ischemic postconditioning显示文摘It is difficult to control the degree of ischemic postconditioning in the brain and other ischemia-sensitive organs.Remote ischemic postconditioning could protect some ischemia-sensitive organs through measures on terminal organs.In this study,a focal cerebral ischemia-reperfusion injury model was established using three cycles of remote ischemic postconditioning,each cycle consisted of 10-minute occlusion of the femoral artery and 10-minute opening.The results showed that,remote ischemic postconditioning significantly decreased the percentage of the infarct area and attenuated brain edema.In addition,inflammatory nuclear factor-κB expression was significantly lower,while anti-apoptotic Bcl-2 expression was significantly elevated in the cerebral cortex on the ischemic side.Our findings indicate that remote ischemic postconditioning attenuates focal cerebral ischemia/reperfusion injury,and that the neuroprotective mechanism is mediated by an anti-apoptotic effect and reduction of the inflammatory response. | Qiang Liu Shengnian Zhou Yaodong Wang Fang Qi Yuan Song Siwei Long | 2014 | Neural Regeneration Research2014，9，15： | 21 |
| 2 | Celastrus orbiculatus extract induces mitochondrial-mediated apoptosis in human hepatocellular carcinoma cells显示文摘OBJECTIVE:To investigate the apoptotic effects and underlying molecular mechanisms of Celastrus orbiculatus(C.orbiculatus) extract in human hepatocellular carcinoma cells.METHODS:Human hepatocellular carcinoma cells(HCCLM6) were treated with C.orbiculatus extract(COE) at different nontoxic concentrations(10,20,40,80,and 160 μg/mL).The effect of COE on HC-CLM6 viability was examined using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide(MTT) assays.Cellular apoptosis following COE treatment was assessed by flow cytometry and western blot analysis.RESULTS:COE significantly inhibited cell viability and induced apoptosis of HCCLM6 cells in a dose-dependent manner.Apoptosis was accompanied by increased Bax expression and decreased Bcl-2 expression.In addition,COE treatment led to the release of cytochrome c,activation of caspase-3,and cleavage of poly(ADP-ribose) polymerase(PARP).Furthermore,activation of extracellular signal-regulated kinase(ERK),p38 kinase,and c-Jun N-terminal kinase(JNK) phosphorylation,and down-regulation of Akt phosphorylation was observed.CONCLUSION:COE induces mitochondrial-mediated,caspase-dependent apoptosis in HCCLM6 cells,which might be attributed to the activation of mitogen-activated protein kinase(MAPK) and inhibition of Akt signaling pathways.These data suggest that COE may be a potential treatment for human hepatocellular carcinoma. | Hua Zhang Yayun Qian Yanqing Liu Guoqing Li Pingfang Cui Yaodong Zhu Hui Ma Xue Ji Shiyu Guo Hisamits Tadashi | 2012 | Journal of Traditional Chinese Medicine2012，32，4： | 18 |
| 3 | Seasonal variability in tropical and subtropical convective and stratiform precipitation of the East Asian monsoon显示文摘Seasonal variations in tropical and subtropical convective and stratiform precipitation of the East Asian monsoon are analyzed using 10-year (1998-2007) Tropical Rainfall Measuring Mission (TRMM) precipitation radar (PR) rain products (2A25). Datasets from the Intergovernmental Panel on Climate Change Fourth Assessment Report (AR4) 24 general circulation models (GCMs) are evaluated using TRMM PR rain products in terms of their ability to simulate convective and stratiform precipitation and their deficiencies. The results show that Asian monsoon convective and stratiform precipitation increases significantly after onset of the summer monsoon, but the percentage of convective precipitation clearly decreases over tropical areas while it increases in subtropical regions. The GCMs simulate well the seasonal variation in the contribution of Asian monsoon subtropical convective precipitation to the total rainfall; however, the simulated convective precipitation amount is high while the simulated stratiform precipitation amount is low relative to TRMM measurements, especially over the Asian monsoon tropical region. There is simultaneous TRMM-observed convective and stratiform precipitation in space and time, but GCMs cannot simulate this relationship between convective and stratiform precipitation, resulting in the deficiency of stratiform precipitation simulations. | HU Liang LI YaoDong SONG Yang DENG DiFei | 2011 | Science China Earth Sciences2011，54，10： | 11 |
| 4 | Influence of fault slip on mining-induced pressure and optimization ofroadway support design in fault-influenced zone显示文摘This paper presents an investigation on the characteristics of overlying strata collapse and mininginduced pressure in fault-influenced zone by employing the physical modeling in consideration of fault structure.The precursory information of fault slip during the underground mining activities is studied as well.Based on the physical modeling,the optimization of roadway support design and the field verification in fault-influenced zone are conducted.Physical modeling results show that,due to the combined effect of mining activities and fault slip,the mining-induced pressure and the extent of damaged rock masses in the fault-influenced zone are greater than those in the uninfluenced zone.The sharp increase and the succeeding stabilization of stress or steady increase in displacement can be identified as the precursory information of fault slip.Considering the larger mining-induced pressure in the fault-influenced zone,the new support design utilizing cables is proposed.The optimization of roadway support design suggests that the cables can be anchored in the stable surrounding rocks and can effectively mobilize the load bearing capacity of the stable surrounding rocks.The field observation indicates that the roadway is in good condition with the optimized roadway support design. | Hongwei Wang Yaodong Jiang Sheng Xue Lingtao Mao Zhinan Lin Daixin Deng Dengqiang Zhang | 2016 | Journal of Rock Mechanics and Geotechnical Engineering2016，8，5： | 10 |
| 5 | Complete chloroplast genome sequences of Schisandra chinensis:genome structure,comparative analysis,and phylogenetic relationship of basal angiosperms显示文摘Dear Editor,Schisandra chinensis(Turcz.)Baill.belongs to family Schisandraceae.Its fruit called'Wu Wei Zi'in Chinese is a well-known medicinal material,which is used to treat chronic cough and dyspnea,nocturnal emission,enuresis,etc.(National Pharmacopoeia Committee,2015).Except for S.chinensis,many species of Schisandraceae,such as S.sphenanthera,S.lancifolia and S.rubriflora,are used as the original plants of folk medicines.Although these species have similar traditional effects,modern | Haojie Guo Jiushi Liul Li Luo Xueping Wei Jin Zhang Yaodong Qi Bengang Zhang Haitao Liu Peigen Xiao | 2017 | Science China(Life Sciences)2017，60，11： | 9 |
| 6 | Application and improvement of an adaptive ensemble Kalman filter for soil moisture data assimilation显示文摘Accurate assignment of model and observation errors is crucial for the successful application of land surface data assimilation algorithms. Poorly-specified model and observation errors can significantly degrade assimilation results. In 2008, Reichle et al. developed an operational procedure to adaptively tune model and observation errors. In this paper, we modified and applied Reichle's procedure in the Noah land surface model to assimilate observed surface soil moisture data. Numerical simulations showed that: (1) the best estimate of model and observation errors appears when the empirical factor β equals 1.02; (2) the Reichle procedure can be deployed to adaptively tune errors if their true values change slowly; and (3) convergence of the Reichle procedure was improved using better initial errors achieved by iterative computations. | Shi XiaoKang Wen Jun Liu JianWen Tian Hui Wang Xin Li YaoDong | 2010 | Science China Earth Sciences2010，53，11： | 8 |
| 7 | Transplantation of primary cultured embryonic mesencephalic neural precursor cells for treating Parkinsonian rats显示文摘BACKGROUND: Choosing proper donor cells is one of keys in experimental and clinical studies on cell replacement therapy (CRT) for treating Parkinson disease (PD). Embryonic mesencephalic precursor cells (MPCs) can stably differentiate into dopaminergic neuron after in vitro proliferated culture. As compared with embryonic stem cell and neural stem cell strains, cell composition of embryonic MPCs after primary culture is also the most close to that of embryonic mesencephalic ventral cell suspension without proliferated culture. Successful experience accumulated in the latter suggests that primary cultured embryonic MPCs might be the most potential donor cells in clinical application with CRT for treating PD so far. OBJECTIVE: To investigate the feasibility of primary cultured embryonic precursor cells cultured primarily as donor cells in CRT for treating PD in rats. DESIGN: A randomized and controlled trial taking SD rats as experimental animals. SETTING: Department of Neurosurgery, Huashan Hospital Affiliated to Fudan University. MATERIALS: This experiment was carried out at the Institute of Neuroscience, Shanghai Institute for Biological Science, Chinese Academy of Sciences from July 2003 to June 2004. Totally 26 female SD rats, with body mass of 200 to 220 g, were provided by Shanghai Experimental Animal Center of Chinese Academy of Sciences. METHODS: Stereotaxic injection of 6-hydroxydopamine into the medial forebrain bundle were perfored to develop PD model rat. Among 26 SD rats, 20 rats achieved a more than 5 turns/min in apomorphine induced rotation test, reaching the standard of PD model rats. Immunohistochemical detection was performed on 1 out of 20 model rats after execution, and the other 19 rats were randomly divided into control group (n=5), sham transplantation group (n=5)and cell grafted group (n=9). Primary cultured E12 MPC cell suspension (1.2×1011 L-1)were used as donor cells. 4 μL primary cultured E12 MPC cell suspension prepared freshly was injected into the lesioned corpus striatum of rats in cell grafted group, and 4 μL D-Hank’s solution was injected in sham transplantation group in the same way. There was no injection in control group. Apomorphine-induced rotation rate of PD rats were recorded respectively in cell grafted group and sham transplantation group pre-operation (initial value) and at postoperative 2, 4, 6 and 16 weeks. Apomorphine-induced rotation rate of PD rats was recorded in control group at postoperative 2 months (initial value) and following 2,4,6 and 16 weeks. To determine TH antigen with immunohistological ABC method (DAB developing) at 6 months post-transplantation to investigate the differentiation and survival of donor cells in the host body. MAIN OUTCOME MEASURES: Apomorphine-induced rotation behavior before and after transplantation and the survival and differentiation of implanted cells in the host body at 6 months post-transplantation. RESULTS: Among 19 model rats, one rat died after transplantation respectively in the cell grafted group and sham transplantation group; finally 17 model rats entered the stage of result analysis. Relative apomorphine-induced rotation rate was significantly decreased in the cell grafted group as compared with that before transplantation, with significant difference (P < 0.01,P < 0.05);the mean value of relative apomorphine-induced rotation rate was significantly decreased at postoperative 16 weeks in cell grafted group as compared with that of corresponding relative rotation rate in control group, also with significant difference (P < 0.05).Immunohistological results showed that donor cells could differentiate into large and multi-polar dopaminergic neurons in the host body. CONCLUSION: Primary cultured embryonic MPCs can be used as the donor cells in CRT for treating PD. | Li Fei Chengchuan Jiang Linyin Feng Yaodong Ji Zhongliang Ding | 2006 | Neural Regeneration Research2006，1，1： | 7 |
| 8 | Photocatalysis:an overview of recent developments and technological advancements显示文摘Photocatalysis,which is the catalyzation of redox reactions via the use of energy obtained from light sources,is a topic that has garnered a lot of attention in recent years as a means of addressing the environmental and economic issues plaguing society today.Of particular interest are photosynthesis can potentially mimic a variety of vital reactions,many of which hold the key to develop sustainable energy economy.In light of this,many of the technological and procedural advancements that have recently occurred in the field are discussed in this review,namely those linked to:(1)photocatalysts made from metal oxides,nitride,and sulfides;(2)photocatalysis via polymeric carbon nitride(PCN);and(3)general advances and mechanistic insights related to TiO2-based catalysts.The challenges and opportunities that have arisen over the past few years are discussed in detail.Basic concepts and experimental procedures which could be useful for eventually overcoming the problems associated with photocatalysis are presented herein. | Yuanxing Fang Yun Zheng Taofang Yong Chen Yaodong Zhu Qing Liang Hua Sheng Zhaosheng Li Chuncheng Chen Xinchen Wang | 2020 | Science China Chemistry2020，63，2： | 7 |
| 9 | The combined influence of surface modification, size distribution, and interaction time on the cytotoxicity of CdTe quantum dots in PANC-1 cells显示文摘Mercaptopropionic 酸(MPA ) 和盖住的 CdTe 量点的 cysteamine (Cys )(QD ) 成功地被准备并且过去常在人的胰腺的癌(PANC-1 ) 在他们的 cytotoxicity 上调查表面修正,尺寸分发,和相互作用时间的联合影响房间。显示的结果那越小 MPA-CdTe QD 的尺寸,越 higher cytotoxicity,它能是部分由于他们在房间内的分发的差别。与 MPA-CdTe QD 作比较, Cys-CdTe QD 最好细胞的 metabolizability 和更低的 cytotoxicity。这些 QD 细胞的分发和 cytotoxicity 是仔细与他们有房间的相互作用时间有关。他们的 cytotoxicity 被发现显著地随媒介的孵化时间的增加被提高。在 QD 处理以后,影响在生存能力也是的最后的房间上恢复时间集中和 QD 的表面修正上的依赖者在预告的处理使用了。这里讨论的这些因素的联合影响可能为在未来理解并且减少 QD 的 cytotoxicity 提供有用信息生物医学的应用。 | Shuquan Chang Bin Kang Xiqin Liu Yaodong Dai Da Chen | 2012 | Acta Biochimica et Biophysica Sinica2012，44，3： | 6 |
| 10 | Ganglioside promotes the bridging of sciatic nerve defects in cryopreserved peripheral nerve allografts显示文摘Previous studies have shown that exogenous gangliosides promote nervous system regeneration and synapse formation.In this study,10 mm sciatic nerve segments from New Zealand rabbits were thawed from cryopreservation and were used for the repair of left sciatic nerve defects through allograft bridging.Three days later,1 m L ganglioside solution(1 g/L) was subcutaneously injected into the right hind leg of rabbits.Compared with non-injected rats,muscle wet weight ratio was increased at 2–12 weeks after modeling.The quantity of myelinated fibers in regenerated sciatic nerve,myelin thickness and fiber diameter were elevated at 4–12 weeks after modeling.Sciatic nerve potential amplitude and conduction velocity were raised at 8 and 12 weeks,while conduction latencies were decreased at 12 weeks.Experimental findings indicate that ganglioside can promote the regeneration of sciatic nerve defects after repair with cryopreserved peripheral nerve allografts. | Yaodong Wang Yuguang Liu Qiang Liu | 2014 | Neural Regeneration Research2014，9，20： | 6 |
| 11 | A comparison study of summer-time synoptic-scale waves in South China and the Yangtze River basin using the TRMM Multi-Satellite Precipitation Analysis daily product显示文摘Summer-time synoptic-scale waves in South China and the Yangtze River basin are quantified and compared by means of analyzing the 6-year (1998―2004) TRMM Multi-Satellite Precipitation Analysis (TMPA) daily product. An innovative 3-dimensional spectrum analysis method is applied. The results indicate that synoptic-scale waves appearing in South China prominently propagate westward within a zonal wavenumber range of 9―21 and a frequency range of-0.12―-0.22 cycles day-1, while those in the Yangtze River basin primarily move eastward with the same characteristic wavenumbers of 9―21, but within a frequency range of 0.2―0.29 cycles day?1. Zonal and meridional distributions, and seasonal variations of these waves are further explored and compared. It shows that summer-time synoptic-scale waves in the South China result from the northward migration and oscillation of the Intertropical Convergence Zone (ITCZ) in the western Pacific, whereas the ones in the Yangtze River basin are generally related to the synoptic troughs within the westerly flow, originating from the Qinghai-Tibet Plateau. | Fu Rong Hu Liang Gu GuoJun Li YaoDong | 2008 | Science China Earth Sciences2008，51，1： | 6 |
| 12 | Numerical investigation on the assessment and mitigation of coal bump in an island longwall panel显示文摘This study presents a numerical investigation to assess the risk of coal bumps and produces a stress–relief technology using boreholes to mitigate risk during the extraction of an island longwall panel.Based on the geological condition in an island longwall panel in the Tangshan Coal Mine,Tangshan,China,a numerical FLAC3D(Fast Lagrangian Analysis of Continua in 3 Dimensions) model was established to determine and to map the zones in the panel with a high risk for coal bumps.The results of the numerical modeling show that the roof deformation starts to occur at more than 30 m ahead of the longwall face and the deformation starts to accelerate after a distance of 10 m in front of the longwall face.Large and rapid roof deformation is considered to be an important precursor of coal bump occurrence during the extraction of an island longwall panel.Based on the numerical results,a stress–relief technology using boreholes,which was employed to release abutment pressure,was investigated through numerical methods.The modeled results suggest that the peak stress concentration could be released by drilling boreholes in the zones prone to coal bumps.The effectiveness of the stress release increased with the borehole length and decreased with the borehole spacing. | Wang Hongwei Jiang Yaodong Zhu Jie Shan Ruyue Wang Chen | 2013 | International Journal of Mining Science and Technology2013，23，5： | 6 |
| 13 | A NOVEL ALGORITHM FOR SIDE PEAKS SUPPRESSION OF AMBIGUITY FUNCTION FOR PASSIVE RADAR BASED ON CHINESE DTTB SIGNAL显示文摘The ambiguity function of Chinese standard Digital Television Terrestrial Broadcasting (DTTB) signals for passive radar contains one main peak and many side peaks. The side peaks may cause the false alarms. The relative positions and the reasons for the side peaks are analyzed and a new algorithm for side peaks suppression is proposed in this paper. The algorithm, in consideration of the characteristics of the structure of the frame, can eliminate the side peaks completely in the valid Doppler observation interval by setting the reference signals to zero at equal intervals. Both the simulative and experimental results show that this algorithm can improve the performance of target detection of the passive radar based on DTTB signal. | Li Jichuan Lu Xiaode Zhao Yaodong | 2012 | Journal of Electronics(China)2012，29，6： | 5 |
| 14 | Organic-semiconductor: Polymer-electret blends for high-performance transistors显示文摘As compared with polymer semiconductors, solution-processed small-moleculesemiconductors usually have poorer film-formation properties, which induceswide variations in device performance in terms of mobility and threshold voltage,thus severely limiting their commercial applications. In this work, we propose aneasily accessible method to improve the performance and reduce the variabilityof small-molecule organic field-effect transistors (OFETs) by blending organicsemiconductors with an insulator polymer, which is subsequently post-treatedby gate stress to generate an electret. By blending the organic semiconductor2,7-didodecyl[1]benzothieno[3,2-b][1]benzothiophene (C12-BTBT) with the insulatorpolystyrene, uniform transport layers with vertically phase segregated morphologyare obtained, from which the mobility and threshold voltage of OFETs are largelymanipulated. The OFETs exhibit field-effect mobilities as high as 7.5 cm2-V-l-s-1with an on/off ratio exceeding 106 in ambient conditions. This double-layerstructure provides an appropriate architecture for applying gate-stress to injectcharges into the insulating layer, forming an electret. The generation of theelectret is thermally accelerated and thus can be easily realized under moderategate-stress at elevated temperature (e.g., 60 ℃). After cooling, the electret layer servesas a floating-gate, which not only continuously tunes the threshold voltage andfield-effect mobility, but also helps minimize the contact resistances and optimizethe subthreshold swing. As an application of this method, a digital inverter isbuilt and its performance is optimized via in situ tuning of its individual transistors. | Peng Wei Shengtao Li Dongfan Li Han Yu Xudong Wang Congcong Xu Yaodong Yang Laju Bu Guanghao Lu | 2018 | Nano Research2018，11，11： | 5 |
| 15 | Dynamics of NDVI and its influencing factors in the Chinese Loess Plateau during 2002-2018显示文摘Understanding the spatio-temporal changes of vegetation and its climatic control factors can provide an important theoretical basis for the protection and restoration of eco-environments.In this study,we analyzed the normalized difference vegetation index(NDVI)in the Chinese Loess Plateau(CLP)from 2002 to 2018 via trend analysis,stability analysis,and Mann-Kendall mutation test to investigate the change of vegetation.In addition,we also used the skewness analysis and correlation analysis to explore the contribution of climate change and human activities on regional vegetation changes.The results indicated that the overall increasing trend of NDVI from 2002 to 2018 was significant The areas showing increased NDVI were mainly distributed in the south-eastern CLP and the irrigation districts of the Yellow River to the north and west of the CLP,while the areas showing decreased NDVl were concentrated in the desert of the westem Ordos Plateau,Longzhong Loess Plateau,and the built-up and adjacent areas.Precipitation was the dominant factor contributing to vegetation growth in the CLP,while vegetation was less dependent onprecipitation in the irigation districts.The increasement of NDVI has led to a prolonged responsetime of vegetation to water stress and a lag effect of less than two months in the CLP.The effect of temperature on NDVI was not significant;significant negative correlations between NDVI and temperature were found only in the desert,the Guanzhong Plain,the southem Liupan Mountains,and the southeastem Taihang Mountains,owing to high temperatures,urban heat islands,and large cloud cover in mountainous areas.Affected by the'Grain for Green Program'(GGP),NDVIin the CLP increased from 2002 to 2018;however,the increasing trends of NDNI for differentvegetation cover types were significantly different owing to the difference in background status.The increasing contribution rate of NDVI in the CLP mainly came from crops and steppes.Urban not only led to the destruction of vegetation but also had radiation effect causing negative impact of NDVI around the cities.This resulted in the aggravation of the negative bias of NDVI with time in the CLP.The results provide a long-term perspective for regional vegetation protection and utilization in the CLP. | Peng He Lishuai Xu Zhengchun Liu Yaodong Jing Wenbo Zhu | 2021 | Regional Sustainability2021，2，1： | 4 |
| 16 | Size,morphology,and composition of lunar samples returned by Chang'E-5 mission显示文摘This study focuses on the physical and chemical properties of surficial lunar regolith(LR)samples returned from the Moon by the Chang’E-5(CE-5)mission.Insights regarding the effect of a new sampling geological site on the surficial lunar sample CE5 C0400 were illustrated using nondestructive techniques such as laser diffractometry coupled with image analysis,X-ray computed tomography,and field emission scanning electron microscopy equipped with energy dispersive spectroscopy,and Xray diffraction combined with Rietveld refinement.From the characterization analyses,the CE-5 sampling site in the northeastern Oceanus Procellarum on the Moon yields a unique collection of relatively regular-shaped and fine basalt-dominated particles.The median grain size D_(50) is(55.24±0.96)μm,falling within the relatively low end of the range of the Apollo lunar returned samples.The coefficient of uniformity C_(u)of 15.1 and the coefficient of curvature C_(c)of 1.7 could classify CE5 C0400 to be well-graded.The minerals in CE5 C0400 comprise approximately 44.5%pyroxene,30.4%plagioclase,3.6%olivine,and6.0%ilmenite.There is a relatively low content of approximately 15.5%glass phase in the CE-5 lunar sample.From the results,we deduce that the CE-5 LR structure could have mainly resulted from micrometeoroid impacts to achieve such a high level of maturity. | Hui Zhang Xian Zhang Guang Zhang Keqi Dong Xiangjin Deng Xiaosong Gao Yaodong Yang Yuan Xiao Xiao Bai Kaixin Liang Yiwei Liu Wenbin Ma Shaofan Zhao Ce Zhang Xiaojing Zhang Jian Song Wei Yao Hong Chen Weihua Wang Zhigang Zou Mengfei Yang | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，2： | 4 |
| 17 | Improved production of docosahexaenoic acid in batch fermentation by newly-isolated strains of Schizochytrium sp.and Thraustochytriidae sp.through bioprocess optimization显示文摘Thraustochytrids,rich in docosahexaenoic acid(DHA,C22:6u3),represent a potential source of dietary fatty acids.Yet,the effect of culture conditions on growth and fatty acid composition vary widely among different thraustochytrid strains.Two different thraustochytrid strains,Schizochytrium sp.PKU#Mn4 and Thraustochytriidae sp.PKU#Mn16 were studied for their growth and DHA production characteristics under various culture conditions.Although they exhibited similar fatty acid profiles,PKU#Mn4 seemed a good candidate for industrial DHA fermentation while PKU#Mn16 displayed growth tolerance to a wide range of process conditions.Relative DHA content of 48.5%and 49.2%(relative to total fatty acids),respectively,were achieved on glycerol under their optimal flask culture conditions.Maximum DHA yield(Yp/x)of 21.0%and 18.9%and productivity of 27.6 mg/L-h and 31.9 mg/L-h were obtained,respectively,in 5-L bioreactor fermentation operated with optimal conditions and dual oxygen control strategy.A 3.4-and 2.8-fold improvement of DHA production(g/L),respectively,was achieved in this study.Overall,our study provides the potential of two thraustochytrid strains and their culture conditions for efficient production of DHA-rich oil. | Qiuzhen Wang Huike Ye Biswarup Sen Yunxuan Xie Yaodong He Sunghoon Park Guangyi Wang | 2018 | Synthetic and Systems Biotechnology2018，3，2： | 4 |
| 18 | A review of mechanism and prevention technologies of coal bumps in China显示文摘Coal bump refers to a sudden catastrophic failure of coal seam and usually can cause serious damages to underground mining facilities and staff. In this circumstance, this paper focuses on the recent achievements in the mechanism and prevention techniques of coal bumps over the past five years in China.Based on theoretical analysis, laboratory experiment, numerical simulation and field test, the characteristics of coal bumps occurrence in China's coal mines were described, and the difference between coal bumps and rockbursts was also discussed. In addition, three categories of coal bumps induced by'material failure' were introduced, i.e. hard roof, floor strata and tectonic structures, in which the mechanism of coal bumps induced by geological structures was analyzed. This involves the bump liability and microstructure effects on bump-prone coal failure, the mechanism of coal bumps in response to fault reactivation, island face mining or hard roof failure. Next, the achievements in the monitoring and controlling methods of coal bumps were reviewed. These methods involve the incorporated prediction system of micro-seismicity and mining-induced pressure, the distributed micro-seismic monitoring system, energy absorption support system, bolts with constant resistance and large elongation,and the 'multi-stage' high-performance support. Finally, an optimal mining design is desirable for the purpose of coal bump mitigation. | Yaodong Jiang Yixin Zhao Hongwei Wang Jie Zhu | 2017 | Journal of Rock Mechanics and Geotechnical Engineering2017，9，1： | 4 |
| 19 | Pine pollen inhibits cell apoptosis-related protein expression in the cerebral cortex of mice with arsenic poisoning显示文摘Previous studies have demonstrated that pine pollen can inhibit cerebral cortical cell apoptosis in mice with arsenic poisoning.The present study sought to detect the influence of pine pollen on apoptosis-related proteins.Immunohistochemistry,western blotting and enzyme-linked immunosorbent assays were used to measure the levels of apoptosis-related proteins in the cerebral cortex of mice with arsenic poisoning.Results indicated that pine pollen suppressed cell apoptosis in the cerebral cortex of arsenic-poisoned mice by reducing Bax,Bcl-2 protein expression and increasing p53 protein expression. | Yanhong Luo Yaodong Wei Taizhong Wang Dongzhu Chen Tiansheng Lu Ruibo Wu Keke Si | 2012 | Neural Regeneration Research2012，7，12： | 4 |
| 20 | On-chip chalcogenide microresonators with low-threshold parametric oscillation显示文摘Chalcogenide glass (ChG) is an attractive material for highly efficient nonlinear photonics,which can cover an ultrabroadband wavelength window from the near-visible to the footprint infrared region. However,it remains a challenge to implement highly-efficient and low-threshold optical parametric processes in chip-scale ChG devices due to thermal and light-induced instabilities as well as a high-loss factor in ChG films. Here,we develop a systematic fabrication process for high-performance photonic-chip-integrated ChG devices,by which planarintegrated ChG microresonators with an intrinsic quality (Q) factor above 1 million are demonstrated. In particular,an in situ light-induced annealing method is introduced to overcome the longstanding instability underlying ChG film. In high-Q ChG microresonators,optical parametric oscillations with threshold power as low as 5.4 mW are demonstrated for the first time,to our best knowledge. Our results would contribute to efforts of making efficient and low-threshold optical microcombs not only in the near-infrared as presented but more promisingly in the midinfrared range. | BIN ZHANG PINGYANG ZENG ZELIN YANG DI XIA JIAXIN ZHAO YAODONG SUN YUFEI HUANG JINGCUI SONG JINGSHUN PAN HUANJIE CHENG DUKYONG CHOI ZHAOHUI LI | 2021 | Photonics Research2021，9，7： | 4 |
您所在的机构暂未开通此部分的功能，请联系管理员