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| 1 | Free fatty acids induce endothelial dysfunction and activate protein kinase C and nuclear factor-κB pathway in rat aorta显示文摘 | Hua Li Hongliang Li Yige Bao Xiangxun Zhang Yerong Yu | 2010 | International Journal of Cardiology2010，，2： | 3 |
| 2 | A simple,disposable microfluidic device for rapid protein concentration and purification via direct-printing显示文摘 | Hui Yu Yu Lu Yige Zhou | 2008 | Lab on a Chip2008，8，9： | 1 |
| 3 | Chronic pulmonary bacterial infection facilitates breast cancer lung metastasis by recruiting tumor-promoting MHCII^(hi) neutrophils显示文摘Breast cancer can metastasize to various organs,including the lungs.The immune microenvironment of the organs to be metastasized plays a crucial role in the metastasis of breast cancer.Infection with pathogens such as viruses and bacteria can alter the immune status of the lung.However,the effect of chronic inflammation caused by bacteria on the formation of a premetastatic niche within the lung is unclear,and the contribution of specific immune mediators to tumor metastasis also remains largely undetermined.Here,we used a mouse model revealing that chronic pulmonary bacterial infection augmented breast cancer lung metastasis by recruiting a distinct subtype of tumor-infiltrating MHCII^(hi) neutrophils into the lung,which exhibit cancer-promoting properties.Functionally,MHCII^(hi) neutrophils enhanced the lung metastasis of breast cancer in a cell-intrinsic manner.Furthermore,we identified CCL2 from lung tissues as an important environmental signal to recruit and maintain MHCII^(hi) neutrophils.Our findings clearly link bacterial-immune crosstalk to breast cancer lung metastasis and define MHCII^(hi) neutrophils as the principal mediator between chronic infection and tumor metastasis. | Teng Ma Yu Tang Taolin Wang Yang Yang Yige Zhang Ruihuan Wang Yongxin Zhang Yi Li Mingbo Wu Miao Tang Xueli Hu Chaoyu Zou Yuan Ren Huan Liu Qianhua Zhang Heyue Li Min Wu Jing Li Xikun Zhou | 2023 | Signal Transduction and Targeted Therapy2023，8，9： | 0 |
| 4 | Characterization of kinesin-like proteins in silkworm posterior silkgland cells显示文摘Kinesins 是涉及各种各样的细胞内部的运输的基于微导管的马达。神经原,鞭打的房间,和颜料房间传统地被用作模型系统学习 kinesins 的细胞的功能。这里,我们报导蚕以后的 silkgland (PSG ) ,为细胞内部的运输和丝心蛋白的有效分泌物与一个广泛的 endomembrane 系统专业化房间,,为 kinesin 学习的一个新奇模型。在 PSG 房间调查驾驶 kinesin 的细胞内部的运输,我们克隆五蚕象 kinesin 一样蛋白质(KLP ) , BmKinesin-1, BmKinesin-6, BmKinesin-7, BmKinesin-13,和 BmKinesin-14A。我们由相对即时 PCR 并且西方的弄污决定了他们的表示模式。Immunofluorescence 显微镜学与微导管验证了他们的 colocalization。由联合下拉试金, LC-MS/MS,和西方的弄污分析,我们在 PSG,包括的包含丝心蛋白的小粒和联系 exuperantia 的 ribonucleoprotein (RNP ) 建筑群识别了 BmKinesin-1 的许多潜在的货物。而且, BmKinesin-13 overexpression 在 BmN 细胞破坏了微导管网络,它与在在另外的有机体调整微导管动力学的 Kinesin-13 的一个角色一致。根据这些结果,我们断定 PSG 可能在阐明有优点在能分泌的纸巾的细胞内部的运输的机制并且能为 kinesin 研究担任一个潜在的模型。 | Qiao Wang Junlin Teng Birong Shen Wei Zhang Yige Guo Xiaolei Su Chuanxi Zhang Albert CH Yu Jianguo Chen | 2010 | Cell Research2010，20，6： | 0 |
| 5 | Mushroom cultivation contributes to Entebbe's economy显示文摘In celebration of the 60th anniversary of the establishment of the diplomatic relations between China and Uganda,a webinar was jointly held on Sept.15 by the Chinese People's Association for Friendship with Foreign Countries,the Chinese Embassy in Uganda,and the Ugandan Embassy in China. | Yu Rui Fan Tingting Huang Yige | 2022 | Changjiang Weekly2022，，37： | 0 |
| 6 | Phytoplanktonic biogeography in the subtropical coastal waters,East China Sea along intensive anthropogenic stresses: roles of environmental versus spatial factors显示文摘Understanding the relative roles of local environmental effects and spatial effects on phytoplankton community is of essential importance to study the biogeography of them at regional scale. However, the determinants that driving the biogeography of phytoplankton communities in the coastal area of northern Zhejiang still remained unclear. We surveyed phytoplankton community compositions in water columns associated with environmental and spatial influences across five subzones that geographically covering this region over four seasons. Diatoms and dinoflagellates were recorded as the main dominant groups and Coscinodiscus oculs-iridis, Coscinodiscus jonesianus, and Skeletonema costatum, were identified as the major abundant species existing in all seasons.Spatially structured environmental conditions, rather than pure spatial or environmental factors, substantially shaped the biogeography of phytoplankton community, with the former mainly comprised of water temperature,dissolved oxygen, phosphate, pH, and salinity, and the latter referring to a non-negligible factor. This study was the first integrated research that combining environmental filtering with spatial factors in structuring phytoplankton communities at a complete tempo-spatial scale. Our results may facilitate to the further study of harmful algal blooms early-warning in this region. | Ran Ye Haibo Zhang Yige Yu Qing Xu Dandi Shen Min Ren Lian Liu Yanhong Cai | 2023 | Acta Oceanologica Sinica2023，42，4： | 0 |
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