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| 1 | Ten cities cross-sectional questionnaire survey of children asthma and other allergies in China显示文摘Asthma,rhinitis and eczema(allergic or non-allergic)have increased throughout the world during the last decades,especially among children.Changes in the indoor environment are suspected to be important causes.China has experienced a dramatic change in indoor environmental exposures during the past two decades.However,such changes and their associations with children’s asthma and other health aspects have not been thoroughly studied.China,Children,Homes,Health(CCHH),Phase I,was a cross-sectional questionnaire survey of 48219 children 1–8 years old in 10 Chinese cities during 2010–2012.The questionnaire includes the International Study of Asthma and Allergies in Childhood(ISAAC)core health questions and additional questions regarding housing,life habits and outdoor environment.In health analyses,children aged 3–6 years old were included.The prevalences of doctor diagnosed asthma varied from 1.7%to 9.8%(mean 6.8%),a large increase from 0.91%in 1999 and 1.50%in2000.The prevalence of wheeze,rhinitis and atopic eczema(last 12 months)varied from 13.9%to 23.7%,24.0%to 50.8%and4.8%to 15.8%,respectively.Taiyuan had the lowest prevalences of all illnesses and Shanghai the highest,except for wheezewhere the highest value was for Urumqi.We found(1)no obvious association between disease prevalences and ambient PM10concentrations and(2)higher prevalences of disease in humid climates with hot summers and cold winters,but with no centrally heated buildings.Associations between the diseases and economic status as indexed by Gross Domestic Product(GDP)requires further study. | ZHANG YinPing LI BaiZhan HUANG Chen YANG Xu QIAN Hua DENG QiHong ZHAO ZhuoHui LI AnGui ZHAO JiaNing ZHANG Xin QU Fang HU Yu YANG Qin WANG Juan ZHANG Ming WANG Fang ZHENG XiaoHong LU Chan LIU ZhiJian SUN YueXia MO JinHan ZHAO YiLi LIU Wei WANG TingTing NORBCK Dan BORNEHAG Carl-Gustaf SUNDELL Jan | 2013 | Chinese Science Bulletin2013，58，34： | 22 |
| 2 | Sensitivity of surface air temperature change to land use/cover types in China显示文摘Using CRU high resolution grid observational temperature and ERA40 reanalysis surface air temperature data during 1960-1999, we investigated the sensitivity of surface air temperature change to land use/cover types in China by subtracting the reanalysis from the observed surface air temperature (observation minus reanalysis, OMR). The results show that there is a stable and systemic impact of land use/cover types on surface air temperature. The surface warming of each land use/cover type reacted differently to global warming. The OMR trends of unused land (≥0.17℃/decade), mainly comprised by sandy land, Gobi and bare rock gravel land, are obviously larger than those of the other land use/cover types. The OMR over grassland, farmland and construction land shows a moderate decadal warming about 0.12℃ /decade, 0.10℃/decade, 0.12 ℃ /decade, respectively. Woodland areas do not show a significant warming trend (0.06 ℃ /decade). The overall assessment indicates that the surface warming is larger for areas that are barren and anthropogenically developed. The better the vegetation cover, the smaller the OMR warming trend. Responses of surface air temperature to land use/cover types with similar physical and chemical properties and biological processes have no significant difference. The surface air temperature would not react significantly until the intensity of land cover changes reach a certain degree. Within the same land use/cover type, areas in eastern China with intensive human activities exhibit larger warming trend. The results provide observational evidence for modeling research on the impact of land use/cover change on regional climate. Thus, projecting further surface climate of China in regional scale should not only take greenhouse gas increase into account, but also consider the impact of land use/cover types and land cover change. | YANG XuChao ZHANG YiLi LIU LinShan ZHANG Wei DING MingJun WANG ZhaoFeng | 2009 | Science China Earth Sciences2009，52，8： | 21 |
| 3 | Climate change in Mt. Qomolangma region since 1971显示文摘Using monthly average, maximum, minimum air temperature and monthly precipitation data from 5 weather stations in Mt. Qomolangma region in China from 1971 to 2004, climatic linear trend, moving average, low-pass filter and accumulated variance analysis methods, the spatial and temporal patterns of the climatic change in this region were analyzed. The main findings can be summarized as follows: (1) There is obvious ascending tendency for the interannual change of air temperature in Mt. Qomolangma region and the ascending tendency of Tingri, the highest station, is the most significant. The rate of increasing air temperature is 0.234 oC/decade in Mt. Qomolangma region, 0.302 oC/decade in Tingri. The air temperature increases more strongly in non-growing season. (2) Compared with China and the global average, the warming of Mt. Qomolangma region occurred early. The linear rates of temperature increase in Mt. Qomolangma region exceed those for China and the global average in the same period. This is attributed to the sensitivity of mountainous regions to climate change. (3) The southern and northern parts of Mt. Qomolangma region are quite different in precipitation changes. Stations in the northern part show increasing trends but are not statistically significant. Nyalam in the southern part shows a decreasing trend and the sudden decreasing of precipitation occurred in the early 1990s. (4) Compared with the previous studies, we find that the warming of Mt. Qomolangma high-elevation region is most significant in China in the same period. The highest automatic meteorological comprehensive observation station in the world set up at the base camp of Mt. Qomolangma with a height of 5032 m a.s.l will play an important role in monitoring the global climate change. | YANG Xuchao ZHANG Yili ZHANG Wei YAN Yuping WANG Zhaofeng DING Mingjun CHU Duo | 2006 | Journal of Geographical Sciences2006，16，3： | 12 |
| 4 | Major advances in studies of the physical geography and living environment of China during the past 70 years and future prospects显示文摘The natural environment provides material essentials for human survival and development. The characteristics,processes, regional differentiation and forcing mechanisms of the elements of the natural environment(e.g. geomorphology,climate, hydrology, soil, etc.) are the main objects of research in physical geography. China has a complex natural environment and huge regional differentiation and therefore it provides outstanding reserach opportunities in physical geography. This review summarizes the most important developments and the main contributions of research in the physical geography and human living environment in China during the past 70 years. The major topics addressed are the uplift of the Tibetan Plateau and the evolution of its cryosphere, the development of fluvial systems, the acidification of the vast arid region of the Asian interior, variations in the monsoon and westerly climate systems on multiple timescales, the development of lakes and wetlands, the watershed system model, soil erosion, past human-environment interactions, biogeography, and physical geographic zonality. After briefly introducing international research developments, we review the history of research in physical geography in China, focusing on the major achievements and major academic debates, and finally we summarize the status of current research and the future prospects. We propose that in the context of the national demand for the construction of an ecological civilization, we should make full use of the research findings of physical geography, and determine the patterns and mechanisms of natural environmental processes in order to continue to promote the continued contribution of physical geography to national development strategies, and to further contribute to the theory of physical geography from a global perspective. | Fahu CHEN Bojie FU Jun XIA Duo WU Shaohong WU Yili ZHANG Hang SUN Yu LIU Xiaomin FANG Boqiang QIN Xin LI Tingjun ZHANG Baoyuan LIU Zhibao DONG Shugui HOU Lide TIAN Baiqing XU Guanghui DONG Jingyun ZHENG Wei YANG Xin WANG Zaijun LI Fei Wang Zhenbo HU Jie WANG Jianbao LIU Jianhui CHEN Wei HUANG Juzhi HOU Qiufang CAI Hao LONG Ming JIANG Yaxian HU Xiaoming FENG Xingguo MO Xiaoyan YANG Dongju ZHANG Xiuhong WANG Yunhe YIN Xiaochen LIU | 2019 | Science China Earth Sciences2019，62，11： | 11 |
| 5 | Determination of interface width value in phase-field simulation of dendritic growth into undercooled melt显示文摘The influence of the interface width value on the simulation results and its dependence upon thermo-physical parameters in the phase-field simulation of dendritic growth into undercooled melt are investigated. After choosing the reasonable interface width value, the tip velocities of dendritic growth in Ni melt under different undercoolings are calculated and compared with the experimental data in order to benchmark our results. It is shown that the reasonable interface width value, which is determined by the undercooling, anisotropy, interface kinetic, and thermal diffusivity, has to be taken low enough, and the agreement of our results with experimental data verifies that the credible results can be achieved as long as the interface width value is adequately low. This paper provides the basis of determining interface width value in simulating dendritic growth into undercooled melt by phase-field approach. | YU Yanmei, YANG Gencang , ZHAO Dawen and LU Yili(State Key Laboratory of Solidification Processing, Northwestern Polytechnical University, Xi’an 710072, China) | 2002 | Progress in Natural Science:Materials International2002，12，3： | 8 |
| 6 | Vegetation change in the Mt. Qomolangma Nature Reserve from 1981 to 2001显示文摘Based on the NOAA AVHRR-NDVI data from 1981 to 2001, the digitalized China Vegetation Map (1:1,000,000), DEM, temperature and precipitation data, and field investiga- tion, the spatial patterns and vertical characteristics of natural vegetation changes and their influencing factors in the Mt. Qomolangma Nature Reserve have been studied. The results show that: (1) There is remarkable spatial difference of natural vegetation changes in the Mt. Qomolangma Nature Reserve and stability is the most common status. There are 5.04% of the whole area being seriously degraded, 13.19% slightly degraded, 26.39% slightly im- proved, 0.97% significantly improved and 54.41% keeping stable. The seriously and slightly degraded areas, which mostly lie in the south of the reserve, are along the national bounda- ries. The areas of improved vegetation lie in the north of the reserve and the south side of the Yarlung Zangbo River. The stable areas lie between the improved and degraded areas. Degradation decreases with elevation. (2) Degeneration in the Mt. Qomolangma Nature Re- serve mostly affects shrubs, needle-leaved forests and mixed forests. (3) The temperature change affects the natural vegetation changes spatially while the integration of temperature changes, slopes and aspects affects the natural vegetation change along the altitude gradi- ents. (4) It is the overuse of resources that leads to the vegetation degeneration in some parts of the Mt. Qomolangma Nature Reserve. | ZHANG Wei ZHANG Yili WANG Zhaofeng DING Mingjun YANG Xuchao LIN Xuedong LIU Linshan | 2007 | Journal of Geographical Sciences2007，17，2： | 7 |
| 7 | Studies of the Genotoxicity of Glycidyl Methacrylate (GMA)显示文摘The following experiments were conducted to evaluate the genotoxic effects of GMA (glycidyl methacrylale) on mammalian and human cells.(1) Using the absorption spectrum shift method in vitro, we observed that the maximums of calf thymus DNA and GMA were shifted toward longer wavelengths (a change of more than 15nm) and the absorbance decreased after incubation at room temperature for 15min or more.The result indicates that binding of DNA and GMA had occurred.The binding force is strong, not affected by the addition of concentrated sodium chloride solution, and only slightly decreased by the addition of 8 M urea solution.Therefore the bond between DNA and GMA might be covalent.(2) In cell cultures, unscheduled DNA synthesis (UDS) in human and/or rat lymphocyte was induced and DNA semiconserva-tive replication was inhibited by GMA at concentrations of less than 5.2 mM.(3) Sperm abnormality tests and assays of UDS in germ cells of male mice were conducted to study the in vivo genotoxicity of GMA.The results revealed that GMA could damage DNA, increase sperm abnormality frequency, and reduce the number of sperm cells, 1990 Academic Press.Inc. | DAYING XIE, WEI ZHANG, LAIFU CAO, WENQING SUN, ZHONGSHENG LI, QING GAO, YILI WU, HUILAN GAO, HUIFANG YANG, JIM ZUO,~* AND FUDE FANG~* Institute oF Occupational Medicine. Chinese Academy ol Preventive Medicine. Beijing 100050. and *Institute of Basic Medical Sciences, Chinese Academy ol Medical Sciences. Beijing 100730, China | 1990 | Biomedical and Environmental Sciences1990，3，3： | 7 |
| 8 | Stable high-level expression of truncated human papillomavirus type 16 L1 protein in Drosophila Schneider-2 cells显示文摘为了改进存在人的乳头状瘤病毒,打 16 (HPV16 ) 像病毒的粒子(VLP ) 准备,果蝇 inducible/secreted 表示系统,一个高度有效的、节俭的方法,被用来生产 HPV16 VLP。果蝇 Schneider-2 房间是有包含没有原子核本地化顺序和选择向量 pCoHygro plasmids,在 4:1 的比率编码 HPV16L1 蛋白质的目标基因的 pMT/BiP/V5-His 表示向量的 cotransfected。stabled hygromycin 抵抗的房间线 1 个月以后被获得,并且蛋白质表示被铜硫酸盐导致。表示 HPV16L1 蛋白质的分子的团是 66 kDa,作为由 SDS 页揭示了,并且由西方的污点分析证实了。HPV16L1 蛋白质的收益每 1 湩攠灸敲獳潩 ? 敬敶是 0.554 mg 吗? | Jin Zheng Xiaofeng Yang Ying Sun Baochang Lai Yili Wang | 2008 | Acta Biochimica et Biophysica Sinica2008，40，5： | 6 |
| 9 | Recent advances in mammalian reproductive biology显示文摘Reproductive biology is a uniquely important topic since it is about germ cells, which are central for transmitting genetic information from generation to generation. In this review, we discuss recent advances in mammalian germ cell development,including preimplantation development, fetal germ cell development and postnatal development of oocytes and sperm. We also discuss the etiologies of female and male infertility and describe the emerging technologies for studying reproductive biology such as gene editing and single-cell technologies. | Lu Wen Qiang Liu Jingjing Xu Xixi Liu Chaoyi Shi Zuwei Yang Yili Zhang Hong Xu Jiang Liu Hui Yang Hefeng Huang Jie Qiao Fuchou Tang Zi-Jiang Chen | 2020 | Science China(Life Sciences)2020，63，1： | 6 |
| 10 | Absolute calibration of HY-2A and Jason-2 altimeters for sea surface height using GPS buoy in Qinglan, China显示文摘GPS buoy methodology is one of the main calibration methodologies for altimeter sea surface height calibration. This study introduces the results of the Qinglan calibration campaign for the HY-2A and Jason-2 altimeters. It took place in two time slices;one was from August to September 2014, and the other was in July 2015. One GPS buoy and two GPS reference stations were used in this campaign. The GPS data were processed using the real-time kinematic (RTK) technique. The fi nal error budget estimate when measuring the sea surface height (SSH) with a GPS buoy was better than 3.5 cm. Using the GPS buoy, the altimeter bias estimate was about -2.3 cm for the Jason-2 Geophysical Data Record (GDR) Version ‘D' and from -53.5 cm to -75.6 cm for the HY-2A Interim Geophysical Data Record (IGDR). The bias estimates for Jason-2 GDR-D are similar to the estimates from dedicated calibration sites such as the Harvest Platform, the Crete Site and the Bass Strait site. The bias estimates for HY-2A IGDR agree well with the results from the Crete calibration site. The results for the HY-2A altimeter bias estimated by the GPS buoy were verifi ed by cross-calibration, and they agreed well with the results from the global analysis method. | CHEN Chuntao ZHU Jianhua ZHAI Wanlin YAN Longhao ZHAO Yili HUANG Xiaoqi YANG Weiwei | 2019 | Journal of Oceanology and Limnology2019，37，5： | 5 |
| 11 | INFLUENCE OF Al-5Ti-1B MASTER ALLOY ON MICROSTRUCTURE AND DAMPING CAPACITY OF ZA27 ALLOY显示文摘1INTRODUCTIONThedampingcapacityofamaterialisameasureoftheenergythatisdissipatedinthematerialduringmechanicalvibrationundercyc... | Zhang, Zhongming Wang, Jincheng Lu, Yili Song, Guangsheng Yang, Gencang Zhou, Yaohe | 1998 | 中国有色金属学会会刊:英文版1998，8，3： | 5 |
| 12 | Neuroprotective effect of Longshengzhi capsule following permanent middle cerebral artery occlusion in rats显示文摘Objective:Longshengzhi capsule(LSZC)is an optimized preparation based on the traditional Chinese Medicine formula Buyanghuanwu Decoction(BYHWD),and is approved by the China Food and Drug Administration for treating stroke-induced disability and vascular diseases.Herein,we examined the pharmacodynamics,anti-apoptotic and anti-oxidant actions,and potential mechanisms of action of LSZC following stroke in rats.Methods:Permanent middle cerebral artery occlusion(MCAO)was used as an ischemic stroke model.LSZC was administered intragastrically.We examined the survival rate,bodyweight,and neurological deficits in stroke rats.Brain infarct size was determined by 2,3,5-triphenyltetrazolium chloride staining.Brain pathology was examined using hematoxylin and eosin staining,Nissl staining,and TdT-mediated dUTP Nick-End Labeling staining.Malondialdehyde,catalase,superoxide dismutase,and glutathione levels were examined by commercial kits.Expression of Nrf2,heme oxygenase-1,Bax,Bcl-2,cleaved caspase-3,and caspase-3 proteins in brain tissue was measured by Western blot.Results:LSZC markedly improved the survival rate and bodyweight,and reduced infarct volume and neurological deficit scores,in MCAO stroke rats.LSZC also significantly attenuated oxidative stress,as indicated by decreased expression of malondialdehyde,and upregulation of Nrf2,heme oxygenase-1,catalase,superoxide dismutase,and glutathione.Moreover,LSZC significantly decreased apoptosis,including a decrease in Bax and cleaved caspase-3 expression,and an increase in Bcl-2,as well as a reduction in numbers of apoptotic neurons.Conclusion:LSZC treatment is neuroprotective against ischemic stroke,potentially via reducing oxidative stress and apoptosis.The Nrf2 and apoptotic signaling pathways may play important roles in the antioxidant and anti-apoptotic actions of LSZC. | Xiaoli Sun Shuzhen Guo Yong Wang Bangze Fu Junjie Liu Yili Zhang Ruocong Yang Chun Li Jian Gao Li Gao Wei Wang | 2020 | Journal of Traditional Chinese Medical Sciences2020，7，1： | 4 |
| 13 | Influence of RE Content on Damping Capacity of Alloy ZA27显示文摘Thedampingcapacityofmaterialsisameasureoftheenergythatisdisipatedinthematerialsduringmechanicalvibrationundercyclicloading.Th... | Zhang, Zhongming Wang, Jincheng Xu, Donghui Lu, Yili Yang, Gencang Zhou, Yaohe | 1999 | Journal of Rare Earths1999，17，2： | 3 |
| 14 | INFLUENCE OF CERIUM CONTENT ON DAMPING CAPACITIES OF AS-SPRAY DEPOSITED HIGH SILICON ALLOY ZA27显示文摘INFLUENCEOFCERIUMCONTENTONDAMPINGCAPACITIESOFASSPRAYDEPOSITEDHIGHSILICONALLOYZA27①LiuYongchang,LuYili,YangGencang,ZhuZhengan... | Liu, Yongchang Lu, Yili Yang, Gencang Zhu, Zhengang | 1997 | 中国有色金属学会会刊:英文版1997，7，1： | 2 |
| 15 | Building a global community of shared future free from poverty显示文摘Poverty alleviation has been highlighted as one of the essential aspects of global development.It has consistently ranked as the top priority among a list of sustainable development goals proposed by the United Nations.1 The coronavirus disease 2019(COVID-19)pandemic has created an unprecedentedly challenging climate for the global economy,society,and populations worldwide,which has consequently intensified socioeconomic inequities among different population groups,especially for the poor and vulnerable.In 2020,global extreme poverty rose for the first time over the past 20 years under the impact of COVID-19,which resulted in an additional 120 million people living in poverty(1.90 USD/day),with the total number of impoverished residents expected to reach approximately 150 million by the end of 2021.2 Such a changing climate has posed a huge obstacle to efforts to alleviate global poverty in terms of improving the affordability,accessibility,adaptability,and equity of medical services for impoverished populations.Under such circumstances,a sustainable strategy for health poverty alleviation needs to be urgently identified and adopted via global efforts to build a global community with shared future free from poverty. | Jay Pan Chu Chen Yili Yang | 2021 | Global Health Journal2021，5，3： | 2 |
| 16 | The diameter factor of aligned membranes facilitates wound healing by promoting epithelialization in an immune way显示文摘Topographical properties,such as pattern and diameter,of biomaterials play important roles in influencing cell activities and manipulating the related immune response during wound healing.We prepared aligned electrospinning membranes with different fiber diameters,including 319±100 nm(A300),588±132 nm(A600),and 1048±130 nm(A1000),by adjusting the distance from the tip to the collector,the injection rate,and the concentration of the solution.The A300 membranes significantly improved cell proliferation and spreading and facilitated wound healing(epithelization and vascularization)with the regeneration of immature hair follicles compared to the other membranes.Transcriptomics revealed the underlying molecular mechanism that A300 could promote immune-related processes towards a pro-healing direction,significantly promoting keratinocyte migration and skin wound healing.All the results indicated that wound healing requires the active participation of the immune process,and that A300 was a potential candidate for guided skin regeneration applications. | Chenbing Wang Chenyu Chu Xiwen Zhao Yang Yang Chen Hu Li Liu Jidong Li Yili Qu Yi Man | 2022 | Bioactive Materials2022，7，5： | 2 |
| 17 | Direction solidification of undercooled melt显示文摘 | Li Jinfu Lü Yili Yang Gencang | 1997 | Progress in Natural Science1997，7，6： | 1 |
| 18 | Failure profile analysis of complex repairable systems with multi ple failure modes 显示文摘 | YANG Qingyu HONG Yili CHEN Yong | 2012 | IEEE Transactions on Reliability2012，61，1： | 1 |
| 19 | Triptolide induces apoptotic death of T lymphocyte 显示文摘 | Yang Yili Liu Zhi-hong Eva Tolosa | 1998 | Immunopharmacology1998，40，2： | 1 |
| 20 | Tip30 has anintrinsic kinase activity required for up-regulation of a subset of apoptotic genes显示文摘 | Hua Xiao Palhan V Yang Yili | 2000 | EMBO J2000，19，5： | 1 |
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