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| 1 | A newly discovered Gigantopithecus fauna from Sanhe Cave, Chongzuo, Guangxi, South China显示文摘Among the most important faunas in the Late Cenozoic, the Gigantopithecus faunas have received a good deal of attention. The Gigantopithecus fauna recently discovered in Sanhe Cave consists of more than 80 mammal species, including cf. Hominidae, Pongo sp., Hylobates sp., Sinomastodon yangzien-sis, Stegodon preorientalis, Cervavitus fenqii, Dicoryphochoerus ultimus and Sus xiaozhu. It is the southernmost Gigantopithecus fauna found so far in China. Its geological age is estimated to be Early Pleistocene based on the fauna and stratigraphic correlation. The significant increase in the estimated body sizes of Ailuropoda, Gigantopithecus and Tapirus shows that the Sanhe fauna is middle Early Pleistocene, later than those from Wushan and Liucheng (early Early Pleistocene). Paleomagnetic dating of the fossil-bearing strata in Sanhe Cave gives an age of approximately 1.2 Ma. The fauna is characterized by tropical-subtropical forest types, including Pongo sp., Tupaia sp., Ia sp., Typhlomys intermedius, etc., and it lacks Palaearctic types. It is a typical tropical forest fauna, suggesting an en-vironment with a lush forest and a warm and humid climate. The discovery of the Sanhe Gigantopith-ecus fauna is significant for establishing the chronological stages of the Gigantopithecus faunas in China, and for discussing their origin, evolution and dynamics. | JIN ChangZhu QIN DaGong PAN WenShi TANG ZhiLu LIU JinYi WANG Yuan DENG ChengLong ZHANG YingQi DONG Wei TONG HaoWen | 2009 | Chinese Science Bulletin2009，54，5： | 14 |
| 2 | The Homo sapiens Cave hominin site of Mulan Mountain,Jiangzhou District,Chongzuo,Guangxi with emphasis on its age显示文摘One of the most hotly debated and frontal issues in paleoanthropology focuses on the origins of modern humans. Recently, an incomplete hominin mandible with a distinctly weaker mental protuberance than modern human and a great variety of coexisting fossil mammals were unearthed from the Homo sapiens Cave of Mulan Mountain, Chongzuo, Guangxi. The mammalian fauna from the Homo sapiens Cave characterized by the combination of Elephas kiangnanensis, first occurring Elephas maixmus, and Megatapirus augustus, and strikingly different from the Early Pleistocene Gigantopithecus fauna and the Middle Pleistocene Ailuropoda-Stogodon fauna of South China could be regarded as an early representive of the typical Asian elephant fauna. Faunal analysis, biostratigraphic correlation, and, most importantly, U-series dating all consistently support an estimate of ca. 110 ka for the age of the fossil Homo sapiens and coexisting mammalian fauna, that is, the early Late Pleistocene. The fauna is mainly made up of tropical-subtropical elements, but grassland elements have a much greater variety than forest elements, which probably indicates a drier climate at that time. This discovery of early Homo sapiens at the Mulan Mountain will play a significant role in the study of the origin and its environmental background of modern humans. | JIN ChangZhu PAN WenShi ZHANG YingQi CAI YanJun XU QinQi TANG ZhiLu WANG Wei WANG Yuan LIU JinYi QIN DaGong R. Lawrence Edwards CHENG Hai | 2009 | Chinese Science Bulletin2009，54，21： | 13 |
| 3 | A four-compartment model for the COVID-19 infection—implications on infection kinetics,control measures,and lockdown exit strategies显示文摘Objective:To analyse the impact and repercussions of the surge in healthcare demand in response to the COVID-19 pandemic,assess the potential effectiveness of various infection/disease control measures,and make projections on the best approach to exit from the current lockdown.Design:A four-compartment model was constructed for SARS-CoV-2 infection based on the Wuhan data and validated with data collected in Italy,the UK,and the US.The model captures the effectiveness of various disease suppression measures in three modifiable factors:(a)the per capita contact rate(β)that can be lowered by means of social distancing,(b)infection probability upon contacting infectious individuals that can be lowered by wearing facemasks,personal hygiene,etc.,and(c)the population of infectious individuals in contact with the susceptible population,which can be lowered by quarantine.The model was used to make projections on the best approach to exit from the current lockdown.Results:The model was applied to evaluate the epidemiological data and hospital burden in Italy,the UK,and the US.The control measures were identified as the key drivers for the observed epidemiological data through sensitivity analyses.Analysing the different lockdown exit strategies showed that a lockdown exit strategy with a combination of social separation/general facemask use may work,but this needs to be supported by intense monitoring whichwould allowre-introduction/tightening of the controlmeasures if the number of newinfected subjects increases again.Conclusions and relevance:Governments should act early in a swift and decisive manner for containment policies.Any lockdown exit will need to be monitored closely,with regards to the potential of lockdown reimplementation.This mathematical model provides a framework for major pandemics in the future. | Tianbing Wang Yanqiu Wu Johnson Yiu-Nam Lau Yingqi Yu Liyu Liu Jing Li Kang Zhang Weiwei Tong Baoguo Jiang | 2020 | Precision Clinical Medicine2020，3，2： | 5 |
| 4 | Development of a psychological first-aid model in inpatients with COVID-19 in Wuhan,China显示文摘Background Facing the social panic and substantial shortage of medical resources during the coronavirus disease 2019(COVID-19)outbreak,providing psychological first-aid to inpatients is essential for their rehabilitation and the orderly operating of medical systems.However,the closed-ward environment and extreme shortage of onsite mental health workers have limited the use of traditional face-to-face diagnosis and psychological interventions.Aim To develop a mental health intervention model for inpatients that can be applied during a widespread epidemic,such as COVID-19.Methods In a medical team stationed in Leishenshan Hospital,Wuhan,China,we integrated onsite and online psychological support resources to implement a graded psychological intervention system.The onsite psychiatrist established trust with the patients and classified them into categories according to their symptom severity.While face-to-face evaluation and intervention are critical for effective online support,the online team effectively extended the scope of the'first-aid'to all patients.Conclusion This integrated onsite and online approach was effective and eficient in providing psychological interventions for inpatients during the crisis.Our model provides a realistic scheme for healthcare systems in or after the COVID-19 epidemic and also could be adopted in areas of the world with insufficient mental healthcare resources. | Wenhong Cheng Fang Zhang Yingqi Hua Zhi Yang Jun Liu | 2020 | General Psychiatry2020，33，3： | 3 |
| 5 | Preparation and electrochemical performance of MWCNTs@MnO_2 nanocomposite for lithium ion batteries显示文摘Tubular nanocomposite with interconnected MnO2 nanoflakes coated on MWCNTs(MWCNTs@MnO2)was fabricated by an aqueous solution method at 80°C.Scanning electron microscopy,X-ray diffraction and galvanostatic charge-discharge tests were used to characterize the structures and electrochemical performances of the as-prepared nanocomposite.The capacity reaches 1233.6 mA h g-1 at a current density of 100 mA g-1 for the first discharge,and it can still maintain a capacity of 633.1mA h g-1 after 100 charge-discharge cycles.The results show that MWCNTs with good electrical conductivity as anchors of MnO2 can provide fast electron transport channels for MnO2 in the electrochemical reactions,and the as-prepared MWCNTs@MnO2 nanocomposite is a potential anode material for lithium ion batteries. | LIU YingQi LI XiuWan WEI ZhiWei ZHANG LiPing WEI XiuCheng HE DeYan | 2014 | Science China(Technological Sciences)2014，57，6： | 2 |
| 6 | Experimental and Numerical Analysis of High-Strength Concrete Beams Including Steel Fibers and Large-Particle Recycled Coarse Aggregates显示文摘In order to study the performances of high-strength concrete beams including steel fibers and large-particle recycled aggregates,four different beams have been designed,tested experimentally and simulated numerically.As varying parameters,the replacement rates of recycled coarse aggregates and CFRP(carbon fiber reinforced polymer)sheets have been considered.The failure mode of these beams,related load deflection curves,stirrup strain and shear capacity have been determined through monotonic loading tests.The simulations have been conducted using the ABAQUS finite element software.The results show that the shear failure mode of recycled concrete beams is similar to that of ordinary concrete beams.The shear carrying capacity of high-strength concrete beams including steel fibers and large-particle recycled coarse aggregates grows with an increase in the replacement rate of recycled coarse aggregates.Reinforcement with CFRP sheets can significantly improve the beam’s shear carrying capacity and overall resistance to deformation. | Chunyang Liu Yangyang Wu Yingqi Gao Zhenyun Tang | 2021 | Fluid Dynamics & Materials Processing2021，17，5： | 2 |
| 7 | Exosomes secreted from cardiomyocytes suppress the sensitivity of tumor ferroptosis in ischemic heart failure显示文摘Heart failure(HF)patients in general have a higher risk of developing cancer.Several animal studies have indicated that cardiac remodeling and HF remarkably accelerate tumor progression,highlighting a cause-and-effect relationship between these two disease entities.Targeting ferroptosis,a prevailing form of non-apoptotic cell death,has been considered a promising therapeutic strategy for human cancers.Exosomes critically contribute to proximal and distant organ-organ communications and play crucial roles in regulating diseases in a paracrine manner.However,whether exosomes control the sensitivity of cancer to ferroptosis via regulating the cardiomyocyte-tumor cell crosstalk in ischemic HF has not yet been explored.Here,we demonstrate that myocardial infarction(MI)decreased the sensitivity of cancer cells to the canonical ferroptosis activator erastin or imidazole ketone erastin in a mouse model of xenograft tumor.Post-MI plasma exosomes potently blunted the sensitivity of tumor cells to ferroptosis inducers both in vitro in mouse Lewis lung carcinoma cell line LLC and osteosarcoma cell line K7M2 and in vivo with xenograft tumorigenesis model.The expression of miR-22-3p in cardiomyocytes and plasma-exosomes was significantly upregulated in the failing hearts of mice with chronic MI and of HF patients as well.Incubation of tumor cells with the exosomes isolated from post-MI mouse plasma or overexpression of miR-22-3p alone abrogated erastin-induced ferroptotic cell death in vitro.Cardiomyocyte-enriched miR-22-3p was packaged in exosomes and transferred into tumor cells.Inhibition of cardiomyocyte-specific miR-22-3p by AAV9 sponge increased the sensitivity of cancer cells to ferroptosis.ACSL4,a pro-ferroptotic gene,was experimentally established as a target of miR-22-3p in tumor cells.Taken together,our findings uncovered for the first time that MI suppresses erastin-induced ferroptosis through releasing miR-22-3p-enriched exosomes derived from cardiomyocytes.Therefore,targeting exosome-mediated cardiomyocyte/tumor pathological communication may offer a novel approach for the ferroptosis-based antitumor therapy. | Ye Yuan Zhongting Mei Zhezhe Qu Guanghui Li Shuting Yu Yingqi Liu Kuiwu Liu Zhihua Shen Jiaying Pu Yanquan Wang Changhao Wang Zhiyong Sun Qian Liu Xiaochen Pang Ao Wang Zijing Ren Tong Wang Ying Liu Jinhuan Hong Jiajie Xie Xin Li Zhonghua Wang Weijie Du Baofeng Yang | 2023 | Signal Transduction and Targeted Therapy2023，8，4： | 2 |
| 8 | Efficient and high-fidelity base editor with expanded PAM compatibility for cytidine dinucleotide显示文摘Cytidine base editor(CBE),which is composed of a cytidine deaminase fused to Cas9 nickase,has been widely used to induce C-to-T conversions in a wide range of organisms.However,the targeting scope of current CBEs is largely restricted to protospacer adjacent motif(PAM)sequences containing G,T,or A bases.In this study,we developed a new base editor termed“nNme2-CBE”with excellent PAM compatibility for cytidine dinucleotide,significantly expanding the genome-targeting scope of CBEs.Using nNme2-CBE,targeted editing efficiencies of 29.0%-55.0%and 17.3%—52.5%were generated in human cells and rabbit embryos,respectively.In contrast to conventional nSp-CBE,the nNme2-CBE is a natural high-fidelity base editing platform with minimal DNA off-targeting detected in vivo.Significantly increased efficiency in GC context and precision were determined by combining nNme2Cas9 with rationally engineered cytidine deaminases.In addition,the Founder rabbits with accurate single-base substitutions at Fgf5 gene loci were successfully generated by using the nNme2-CBE system.These novel nNme2-CBEs with expanded PAM compatibility and high fidelity will expand the base editing toolset for efficient gene modification and therapeutic applications. | Zhiquan Liu Siyu Chen Yingqi Jia Huanhuan Shan Mao Chen Yuning Song Liangxue Lai Zhanjun Li | 2021 | Science China(Life Sciences)2021，64，8： | 2 |
| 9 | Therapeutic effects of TACI-Ig on collagen-induced arthritis by regulating T and B lymphocytes function in DBA/1 mice 显示文摘 | LIU Yuejie ZHANG Lingling WU Yingqi | 2011 | European Journal of Pharmacology2011，654，3： | 1 |
| 10 | Medical Additive Manufacturing: From a Frontier Technology to the Research and Development of Products显示文摘1.Research and development(R&D)and the challenges of raw materials for medical additive manufacturing Raw materials for medical additive manufacturing have a wide range of commonalities that are also seen in many other fields,making them an important basis in the field of three-dimensional(3D)printing.Problems and challenges related to material types,powder properties,formability,viscoelasticity,and so forth also share common features.For example,many metal materials are used in the field of aviation,while metals,polymers,and inorganic materials are used in the field of biomedicine.The most widely used materials in biomedicine are biocompatible.Various homogeneous and non-homogeneous composites are also available for 3D printing,and impose an additional challenge in additive manufacturing;the use of heterogeneous composites in 3D printing is particularly challenging. | Guixing Qiu Wenjiang Ding Wei Tian Ling Qin Yu Zhao Lianmeng Zhang Jian Lu Daijie Chen Guangyi Yuan Chengtie Wu Bingheng Lu Ruxu Du Jimin Chen Mo Elbestawi Zhongwei Gu Dichen Li Wei Sun Yuanjin Zhao Jie He Dadi Jin Bin Liu Kai Zhang Jianmo Li Kam WLeong Dewei Zhao Dingjun Hao Yingfang Ao Xuliang Deng Huilin Yang ShaoKeh Hsu Yingqi Chen Long Li Jianping Fan Guohui Nie Yun Chen Hui Zeng Wei Chen Yuxiao Lai | 2020 | Engineering2020，6，11： | 1 |
| 11 | Causal Links between Foreign Direet Investment and Trade in China 显示文摘 | Xiaming Liu Chengang Wang Yingqi Wei | 2001 | China Economic Review2001，，12： | 1 |
| 12 | NEV Technology in China 显示文摘 | Yingqi Liu Kokko A | 2012 | Chinese Management Studies2012，，6： | 1 |
| 13 | Determinants of Bilateral Trade Flows in OECD Countries: Evidence from Gravity Panel Data Models显示文摘 | Chengang Wang Yingqi Wei Xiaming Liu | 2010 | The World Economy2010，，： | 1 |
| 14 | Analysis of tumor‐induced lymphangiogenesis and lymphatic vessel invasion of pancreatic carcinoma in the peripheral nerve plexus显示文摘 | Peng Cheng Gang Jin Xiangui Hu Min Shi Yijie Zhang Rui Liu Yingqi Zhou Chenghao Shao Jianming Zheng Minghua Zhu | 2012 | Cancer Sci2012，，10： | 1 |
| 15 | Effects of florfenicol exposure on growth,development and antioxidant capacity of flounder Paralichthys olivaceus larvae at different developmental stages显示文摘Antibiotics are widespread in various environmental media,and may pose a potential threat to aquatic ecosystems and non-target aquatic organisms.Florfenicol(FLO)is one of the most commonly used antibiotics in aquaculture,and extensively used to substitute chloramphenicol with its strong sterilization and low adverse ef fect.In this study,flounder Paralichthys olivaceus,an important economic fish species in seawater was used as an experimental subject.Five exposure concentrations of FLO(including environmentrelated concentrations)were set at 0,0.01,0.1,1,and 10 mg/L.Ef fects of FLO exposure for 168 h on growth and development,motor behavior,antioxidant enzyme activity,malondialdehyde(MDA)content,and thyroid hormone level of P.olivaceus larvae were studied in pre-larvae(1 dpf)and post-larvae(20 dpf).The results show that the short-term FLO exposure could promote the larvae growth to some degrees,but inhibit them as the exposure time prolonged.For pre-larvae,FLO at 0.01 mg/L could stimulate the motor nerve system and increase the swimming ability,but inhibited it at 1 mg/L.With the increasing dosage of FLO,the superoxide dismutase(SOD)and MDA contents were elevated,reaching the maximum in the 1 mg/L FLO group.The pre-larvae were more sensitive than the post-larvae to FLO in the environment,and the growth and immune resistance could be damaged with long exposure.Post-larvae were more tolerant to external pollutants,FLO at 1 mg/L could promote the motor behavior and reduce SOD and MDA contents.Therefore,FLO can be used as an antibiotic at a proper concentration but as a drug to prevent disease in a long-term way. | GUO Rui ZHANG Yingqi ZHANG Xianyu ZHANG Qian CHENG Rui MD MOSTAFIZUR Rahman LIU Ying | 2020 | Journal of Oceanology and Limnology2020，38，2： | 1 |
| 16 | Analysis of tumor‐induced lymphangiogenesis and lymphatic vessel invasion of pancreatic carcinoma in the peripheral nerve plexus显示文摘 | Peng Cheng Gang Jin Xiangui Hu Min Shi Yijie Zhang Rui Liu Yingqi Zhou Chenghao Shao Jianming Zheng Minghua Zhu | 2012 | Cancer Sci2012，，10： | 1 |
| 17 | Improving Thermal and Flame Retardant Properties of Epoxy Resin with Organic NiFe-Layered Double Hydroxide-Carbon Nanotubes Hybrids显示文摘在环氧基树脂树脂(EP ) 改进碳 nanotubes (CNT ) 和分层的双氢氧化物(LDH ) 的火焰 retardancy 的分散,器官的镍铁分层的双氢氧化物(ONiFe-LDH-CNTs ) 混血儿通过一起沉淀被装配。这些混血儿进一步被用作增强 filler in EP。与 ONiFe-LDH 和 CNT 的不同比率包含 ONiFe-LDH-CNTs 的 4 wt% 的 EP/ONiFe-LDH-CNTs nanocomposites 被治好的超声的分散和节目温度准备。获得的混血儿的结构和形态学被不同技术描绘。在 EP 矩阵的 nanofillers 的分散被传播电子显微镜学(TEM ) 观察。结果揭示了 exfoliated 的共存并且设置在聚合物矩阵的 ONiFe-LDH- CNT。有 EP 矩阵的上述 nanofillers 的强壮的联合提供了一有效热并且为 nanocomposites 的火焰 retardant 改进。它证明 EP/ONiFe-LDH-CNTs nanocomposites 与 EP 相比展出了优异火焰 retardant 和热性质。如此的改进热性质能被归因于更好同类的分散,更强壮的界面的相互作用, ONiFe-LDH 的优秀 charring 表演和在 ONiFe-LDH 和 CNT 之间的 synergistic 效果。 | Qinghong Kong Ting Wu Yingqi Tang Lemin Xiong Hong Liu Junhao Zhang Ruihua Guo Feng Zhang | 2017 | Chinese Journal of Chemistry2017，35，12： | 1 |
| 18 | Productivity Spillovers from Foreign Direct Invest- ment: Evidence from UK Industry Level Panel Data 显示文摘 | Liu Xiaming Plamela Siler Wang Chengqi and Wei Yingqi | 2000 | Journal of International Business Studies2000，，31： | 1 |
| 19 | The Regional Distribution of Foreign Direct Investment in China显示文摘 | Yingqi Wei Xiaming Liu David Parker Kirit Vaidya | 1999 | Regional Studies1999，，9： | 1 |
| 20 | Role of government subsidies in the new energy vehicle charging infrastructure industry:a three-party game perspective显示文摘With the new round of scientific and technological revolution and industrial transformation,China has posited the direction of“new infrastructure”in 2020.As one of the seven major industries of the“new infrastructure”,the charging infrastructure(CI)industry not only supports the upgrade of the new energy vehicle industry but also provides developing platforms for emerging industries,such as wireless charging,energy storage,smart microgrid,and new energy consumption.Therefore,the government’s supporting role is crucial for the CI industry.To effectively explore the effectiveness of government’s subsidy policy in the CI industry and promote its healthy development,we employed a game model and discussed the government's evolution process of different game strategies between CI and battery-swapping station(BSS)operators in this study.First,China's government subsidies for the electric vehicle(EV)industry were classified into CIs and BSSs.The subsidies obtained by the CI operators were operating subsidies,whereas those obtained by BSSs were investment subsidies.Second,a game model was constructed,involving the government,operators,and users.The model used backward induction to seek the refined Nash equilibrium solution for CIs and BSS operators.The Nash equilibrium solution indicated that the optimal investment amount and BSS quantity of the operator were positively correlated with the government subsidy intensity.When the profitability of the operators increased and the amount of the subsidies increased,consumers’willingness to use EVs increased and the policy effects were closely related to the benefits of government management.The decisions made by either the users or the operators were inversely related to the operators’management efficiency.Besides,the subsidy policy was affected by the government management.Therefore,in the implementation stage of the government’s future subsidy policies,the government needs to innovate and improve management effectiveness.The government could use subsidy policies as a driving force for developing the CI industry to build a comprehensive ecosystem of the industry,which is also the next key point for the government to promote the development of the CI industry in the future. | Weizhong Yue Yingqi Liu Yu Tong Zeyuan Song | 2021 | Chinese Journal of Population,Resources and Environment2021，19，2： | 1 |
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