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| 1 | Ultrathin Al2O3-coated reduced graphene oxide membrane for stable lithium metal anode显示文摘Lithium(Li) metal has been considered as the most attractive anode materials for Li-ion batteries(LIBs)due to its high theoretic specific capacity. The formation of unstable solid electrolyte interphase(SEI) and dendritic Li on the metal anode, however, hindered its practical application. Herein, to address the issues, a Li-free electrode with ultrathin Al_2O_3 coated on reduced graphene oxide(rGO) membrane that covers a Cu foil current collector was developed. The composite electrode exhibits excellent interfacial protection of lithium metal deposited between Cu foil and rGO electrochemically. Firstly, it affords good Li^+ permeability from the electrolyte. Secondly, the ultrathin Al_2O_3 has sufficient mechanical strength to inhibit the penetration of Li dendrite. Li metal was observed uniformly deposited between rGO membrane and Cu collector, and stable cycle performance of Li plating/stripping with Coulombic efficiency of ~91.75% at the 100 th cycle is achieved in organic carbonate electrolyte without any additives. | Fan Zhang Fei Shen ZhaoYang Fan Xin Ji Bin Zhao ZhouTing Sun YingYing Xuan XiaoGang Han | 2018 | Rare Metals2018，37，6： | 11 |
| 2 | Single-cell analysis reveals bronchoalveolar epithelial dysfunction in COVID-19 patients显示文摘Dear Editor,In 2019,a zoonotic coronavirus named severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)was identified as the causative agent of Coronavirus Disease 2019(COVID-19).As of 8 June 2020,the World Health Organization(WHO)has reported 6,912,751 globally confirmed cases with 400,469 deaths.Although generally causes mild disease,SARS-CoV-2 infection can result in serious outcomes,including acute lung injury(ALI)and acute respiratory distress syndrome(ARDS),the leading cause of mortality in patients with comorbidities.Recent autopsy studies of COVID-19 patients revealed mononuclear infiltration and excessive production of mucus in the infected lung,especially in the damaged small airways and alveoli(Bian and Team,2020;Liu et al.,2020). | Jiangping He Shuijiang Cai Huijian Feng Baomei Cai Lihui Lin Yuanbang Mai Yinqiang Fan Airu Zhu Huang Huang Junjie Shi Dingxin Li' Yuanjie Wei Yueping Li Yingying Zhao’ Yuejun Pan He Liu Xiaoneng Mo Xi He Shangtao Cao FengYu Hu Jincun Zhao Jie Wang Nanshan Zhong Xinwen Chen Xilong Deng Jiekai Chen | 2020 | Protein & Cell2020，11，9： | 7 |
| 3 | Progress in electrolytes for rechargeable Li-based batteries and beyond显示文摘Owing to almost unmatched volumetric energy density, Li-based batteries have dominated the portable electronic industry for the past 20 years. Not only will that continue, but they are also now powering plug-in hybrid electric vehicles and zero-emission vehicles. There is impressive progress in the exploration of electrode materials for lithium-based batteries because the electrodes(mainly the cathode) are the limiting factors in terms of overall capacity inside a battery. However, more and more interests have been focused on the electrolytes, which determines the current(power) density, the time stability, the reliability of a battery and the formation of solid electrolyte interface. This review will introduce five types of electrolytes for room temperature Li-based batteries including 1) non-aqueous electrolytes, 2) aqueous solutions, 3)ionic liquids, 4) polymer electrolytes, and 5) hybrid electrolytes. Besides, electrolytes beyond lithium-based systems such as sodium-, magnesium-, calcium-, zinc-and aluminum-based batteries will also be briefly discussed. | Qi Li Juner Chen Lei Fan Xueqian Kong Yingying Lu | 2016 | Green Energy & Environment2016，1，1： | 6 |
| 4 | Transformers in computational visual media:A survey显示文摘Transformers,the dominant architecture for natural language processing,have also recently attracted much attention from computational visual media researchers due to their capacity for long-range representation and high performance.Transformers are sequence-to-sequence models,which use a selfattention mechanism rather than the RNN sequential structure.Thus,such models can be trained in parallel and can represent global information.This study comprehensively surveys recent visual transformer works.We categorize them according to task scenario:backbone design,high-level vision,low-level vision and generation,and multimodal learning.Their key ideas are also analyzed.Differing from previous surveys,we mainly focus on visual transformer methods in low-level vision and generation.The latest works on backbone design are also reviewed in detail.For ease of understanding,we precisely describe the main contributions of the latest works in the form of tables.As well as giving quantitative comparisons,we also present image results for low-level vision and generation tasks.Computational costs and source code links for various important works are also given in this survey to assist further development. | Yifan Xu Huapeng Wei Minxuan Lin Yingying Deng Kekai Sheng Mengdan Zhang Fan Tang Weiming Dong Feiyue Huang Changsheng Xu | 2022 | Computational Visual Media2022，8，1： | 6 |
| 5 | Dispersion stability of thermal nanofluids显示文摘Thermal nanofluids, the engineered fluids with dispersed functional nanoparticles, have exhibited extraordinary thermophysical properties and added functionalities, and thus have enabled a broad range of important applications. The poor dispersion stability of thermal nanofluids, however, has been considered as a longexisting issue that limits their further development and practical application. This review overviews the recent efforts and progresses in improving the dispersion stability of thermal nanofluids such as mechanistic understanding of dispersion behavior of nanofluids, examples of both water-based and oil-based nanofluids,strategies to stabilize nanofluids, and characterization techniques for dispersion behavior of nanofluids. Finally,on-going research needs, and possible solutions to research challenges and future research directions in exploring stably dispersed thermal nanofluids are discussed. | Fan Yu Yingying Chen Xingbo Liang Jiale Xu Chiahsun Lee Qi Liang Peng Tao Tao Deng | 2017 | Progress in Natural Science:Materials International2017，27，5： | 5 |
| 6 | High-density genetic map construction and identification of loci controlling flower-type traits in Chrysanthemum(Chrysanthemum×morifolium Ramat.)显示文摘Flower type is an important and extremely complicated trait of chrysanthemum.The corolla tube merged degree(CTMD)and the relative number of ray florets(RNRF)are the two key factors affecting chrysanthemum flower type.However,few reports have clarified the inheritance of these two complex traits,which limits directed breeding for flower-type improvement.In this study,305 F1 hybrids were obtained from two parents with obvious differences in CTMD and RNRF performance.Using specific-locus amplified fragment sequencing(SLAF-seq)technology,we constructed a high-density genetic linkage map with an average map distance of 0.76 cM.Three major QTLs controlling CTMD and four major QTLs underlying RNRF were repeatedly detected in the 2 years.Moreover,the synteny between the genetic map and other Compositae species was investigated,and weak collinearity was observed.In QTL regions with a high degree of genomic collinearity,eight annotated genes were probed in the Helianthus annuus L.and Lactuca sativa L.var.ramosa Hort.genomes.Furthermore,20 and 11 unigenes were identified via BLAST searches between the SNP markers of the QTL regions and the C.vestitum and C.lavandulifolium transcriptomes,respectively.These results lay a foundation for molecular marker-assisted breeding and candidate gene exploration in chrysanthemum without a reference assembly. | Xuebin Song Yuhui Xu Kang Gao Guangxun Fan Fan Zhang Chengyan Deng Silan Dai He Huang Huaigen Xin Yingying Li | 2020 | Horticulture Research2020，7，1： | 5 |
| 7 | Methylation of RAR-β2, RASSF1A, and CDKN2A Genes Induced by Nickel Subsulfide and Nickel-carcinogenesis in Rats显示文摘Objective To investigate the expression variation of RAR‐β2, RASSF1A, and CDKN2A gene in the process of nickel‐induced carcinogenesis. Methods Nickel subsulfide (Ni 3 S 2 ) at dose of 10 mg was given to Wistar rats by intramuscular injection. The mRNA expression of the three genes in induced tumors and their lung metastasis were examined by Real‐time PCR. The methylation status of the 5' region of these genes were detected by Quantitative Real‐time methylation specific PCR. Results The mRNA expressions of the three genes both in muscle and lung tumor were decreased distinctly in comparison with normal tissue. But hypermethylation was found only in muscle tumor. Conclusion These findings suggest that loss of function or decrease of RAR‐β2, RASSF1A, and CDKN2A, as well as the hypermethylation of 5' region of these genes, are related with nickel exposure. | ZHANG Jun ZHANG Jing LI MengJie Wu YouJun FAN YingYing ZHOU Yang TAN LiLi SHAO ZhiHua SHI HongJun | 2011 | Biomedical and Environmental Sciences2011，24，2： | 4 |
| 8 | Diagonal-symmetrical and Midline-symmetrical Unit Cells with Same Porosity for Bone Implant: Mechanical Properties Evaluation显示文摘In this study, mechanical properties of bionic porous structures with diagonal-symmetrical and midline-symmetrical unit cells were studied when the porosities were same. Three typical unit cells (Diamond (DO), Rhombic Dodecahedron (RD), and Octet Truss (OT)) were selected, in which DO has diagonal-symmetrical shape, while RD and OT share midline-symmetrical structure. Based on the same porosity, corresponding models were designed, and Ti6Al4V samples were manufactured by electron beam melting. Then, using Mechanical Properties Testing (MPT) and Finite Element Analysis (FEA) methodologies, mechanical properties and transmissions of different porous structures were evaluated. Besides, composition and details before and after printing were analyzed with Energy Dispersive Spectrometer (EDS), X-ray diffraction (XRD) and Scanning Electron Microscope (SEM). MPT results showed that midline-symmetrical shape would have superior compressive performance than diagonal-symmetrical shape, but opposite trend for the torsion performance, which were in line with FEA prediction. Furthermore, effective modulus of DO, RD and OT were 2.59 GPa, 4.89 GPa, and 1.77 GPa, approximating the mechanical properties of human bones. Additionally, manufacturing defects and discrepancies between FEA and MPT were found. This study would provide great helps for unit cell selection and initial mechanical properties matching for optimum bone implants. | Jian Li Diansheng Chen Yingying Zhang Yan Yao Zhongjun Mo Lizhen Wang Yubo Fan | 2019 | Journal of Bionic Engineering2019，16，3： | 4 |
| 9 | The spatial scaling effect of the discrete-canopy effective leaf area index retrieved by remote sensing显示文摘The leaf area index(LAI) is a critical biophysical variable that describes canopy geometric structures and growth conditions.It is also an important input parameter for climate,energy and carbon cycle models.The scaling effect of the LAI has always been of concern.Considering the effects of the clumping indices on the BRDF models of discrete canopies,an effective LAI is defined.The effective LAI has the same function of describing the leaf density as does the traditional LAI.Therefore,our study was based on the effective LAI.The spatial scaling effect of discrete canopies significantly differed from that of continuous canopies.Based on the directional second-derivative method of effective LAI retrieval,the mechanism responsible for the spatial scaling effect of the discrete-canopy LAI is discussed and a scaling transformation formula for the effective LAI is suggested in this paper.Theoretical analysis shows that the mean values of effective LAIs retrieved from high-resolution pixels were always equal to or larger than the effective LAIs retrieved from corresponding coarse-resolution pixels.Both the conclusions and the scaling transformation formula were validated with airborne hyperspectral remote sensing imagery obtained in Huailai County,Zhangjiakou,Hebei Province,China.The scaling transformation formula agreed well with the effective LAI retrieved from hyperspectral remote sensing imagery. | FAN WenJie GAI YingYing XU XiRu YAN BinYan | 2013 | Science China Earth Sciences2013，56，9： | 4 |
| 10 | Dynamic cell transition and immune response landscapes of axolotl limb regeneration revealed by single-cell analysis显示文摘Dear Editor,The axolotl,Ambystoma mexicanum,has extraordinary capability to fully recover multiple tissues after lost,whereas such capability has disappeared in mammals.Thus,deci-phering detailed mechanisms underlying axolotl regenera-tion could provide valuable lessons for regenerative medicine.However,many questions,such as the origin of essential progenitor cells and key responses of individual types of cells for regeneration remain elusive(Haas and Whited,2017).Newly developed single-cell RNA sequenc-ing(scRNA-seq)method enables researchers to observe cellular and molecular dynamics in axolotl regeneration at the single-cell resolution(Gerber et al.,2018;Leigh et al.,2018),but the reported transcriptome landscapes are only for certain cell types or in certain regenerative stages.A complete overview of the regeneration process for all cell types is still lacking. | Hanbo Li Xiaoyu Wei Li Zhou Weiqi Zhang Chen Wang Yang Guo Denghui Li Jjianyang Chen Tianbin Liu Yingying Zhang Shuai Ma Congyan Wang Fujian Tan Jiangshan Xu Yang Liu Yue Yuan Liang Chen Qiaoran Wang Jing Qu Yue Shen Shanshan Liu Guangyi Fan Longqi Liu Xin Liu Yong Hou Guang-Hui Liu Ying Gu Xun Xu | 2021 | Protein & Cell2021，12，1： | 3 |
| 11 | Burden of Disease Due to Cancer——China,2000-2019显示文摘Summary What is already known about this topic?Cancer is a major global public health problem and the leading cause of death in China.China has a large population,and therefore has a significant proportion of the global burden of cancer.What is added by this report?The age-standardized incidence of cancer has increased in China,while the cancer mortality rate has decreased.Compared with younger age groups,individuals over 70 have a greater burden of cancer.Digestive tract cancer and breast cancer should be targeted for prevention,treatment,and control. | Xueqi Fan Bin Zhang Yuan He Xiaolong Zhou Yingying Zhang Li Ma Xudong Li Jing Wu | 2022 | China CDC weekly2022，4，15： | 3 |
| 12 | Human Vγ9Vδ2-T cells efficiently kill influenzavirus-infected lung alveolar epithelial cells显示文摘 | Hong Li Zheng Xiang Ting Feng Jinrong Li Yinping Liu Yingying Fan Qiao Lu Zhongwei Yin Meixing Yu Chongyang Shen Wenwei Tu | 2013 | Cellular & Molecular Immunology2013，10，2： | 3 |
| 13 | Laser-induced Janus graphene/poly(p-phenylene benzobisoxazole)fabrics with intrinsic flame retardancy as flexible sensors and breathable electrodes for fire-fighting field显示文摘Conventional firefighting clothing and fire masks can protect firemen’s safety to a certain extent,whereas cannot perceive environmental hazards and monitor their physical status in real time.Herein,we fabricated two kinds of Janus graphene/poly(pphenylene benzobisoxazole)(PBO)fabrics by laser direct writing approach and evaluated their performance as intelligent firefighting clothes and fire masks.The results showed that the Janus graphene/PBO fabrics were virtually non-combustible and achieved the highest thermal protection time of 18.91 s ever reported in flame,which is due to the intrinsic flame-retardant nature of PBO fibers.The graphene/PBO woven fabrics-based sensor showed good repeatability and stability in human motion monitoring and NO_(2)gas detection.Furthermore,the piezoelectric fire mask was assembled with graphene/PBO nonwoven fabric as electrode layer and polyvinylidene fluoride(PVDF)electrostatic direct writing film as piezoelectric layer.The filtration efficiency of the fire mask reaches 95%for PM_(2.5)and 100%for PM_(3.0),indicating its effective filtration capability for smoke particles in fires.The respiratory resistance of the piezoelectric fire mask(46.8 Pa)was lower than that of commercial masks(49 Pa),showing that it has good wearing comfort.Besides,the piezoelectric fire mask can be sensitive to the speed and intensity of human breathing,which is essential for indirectly reflecting the health of the human body.Consequently,this work provides a facile approach to fabricate next-generation intrinsic flame-retardant smart textiles for smart firefighting. | Yu Luo Yaping Miao Huimin Wang Kai Dong Lin Hou Yanyan Xu Weichun Chen Yao Zhang Yingying Zhang Wei Fan | 2023 | Nano Research2023，16，5： | 2 |
| 14 | Multi-omic characterization of genome-wide abnormal DNA methylation reveals diagnostic and prognostic markers for esophageal squamous-cell carcinoma显示文摘This study investigates aberrant DNA methylations as potential diagnosis and prognosis markers for esophageal squamous-cell carcinoma(ESCC),which if diagnosed at advanced stages has<30%five-year survival rate.Comparing genome-wide methylation sites of 91 ESCC and matched adjacent normal tissues,we identified 35,577 differentially methylated CpG sites(DMCs)and characterized their distribution patterns. | Yiyi Xi Yuan Lin Wenjia Guo Xinyu Wang Hengqiang Zhao Chuanwang Miao Weiling Liu Yachen Liu Tianyuan Liu Yingying Luo Wenyi Fan Ai Lin Yamei Chen Yanxia Sun Yulin Ma Xiangjie Niu Ce Zhong Wen Tan Meng Zhou Jianzhong Su Chen Wu Dongxin Lin | 2022 | Signal Transduction and Targeted Therapy2022，7，3： | 2 |
| 15 | Sustainable Investment Forecasting of Power Grids Based on theDeep Restricted Boltzmann Machine Optimized by the Lion Algorithm显示文摘This paper proposes a new power grid investment prediction model based on the deep restricted Boltzmann machine(DRBM)optimized by the Lion algorithm(LA).Firstly,two factors including transmission and distribution price reform(TDPR)and 5G station construction were comprehensively incorporated into the consideration of influencing factors,and the fuzzy threshold method was used to screen out critical influencing factors.Then,the LA was used to optimize the parameters of the DRBM model to improve the model’s prediction accuracy,and the model was trained with the selected influencing factors and investment.Finally,the LA-DRBM model was used to predict the investment of a power grid enterprise,and the final prediction result was obtained by modifying the initial result with the modifying factors.The LA-DRBMmodel compensates for the deficiency of the singlemodel,and greatly improves the investment prediction accuracy of the power grid.In this study,a power grid enterprise was taken as an example to carry out an empirical analysis to prove the validity of the model,and a comparison with the RBM,support vector machine(SVM),back propagation neural network(BPNN),and regression model was conducted to verify the superiority of the model.The conclusion indicates that the proposed model has a strong generalization ability and good robustness,is able to abstract the combination of low-level features into high-level features,and can improve the efficiency of the model’s calculations for investment prediction of power grid enterprises. | Qian Wang Xiaolong Yang Di Pu Yingying Fan | 2022 | Computer Modeling in Engineering & Sciences2022，，1： | 2 |
| 16 | Timely renal replacement therapy linked to better outcome in patients with sepsis-associated acute kidney injury显示文摘Background:Recent studies suggest that acute kidney injury(AKI)can be treated with renal replacement therapy(RRT).However,its benefits to patients with sepsis-associated AKI(SA-AKI),which is linked to high mortality and morbidity rates,remain under debate.The aim of this study was to compare the outcomes of different RRT strategies for patients with SA-AKI.Methods:This retrospective study evaluated patients who were admitted to the hospital with sepsis and devel-oped SA-AKI during hospitalization from 1st January 2014 to 31st January 2019.Mortality,renal recovery,and systemic organ function at 90 days following admission were compared between the RRT group(RG)and non-RRT group(NRG),as well as the early-RRT group(EG)and delayed-RRT group(DG).The groups were defined according to the time from admission to RRT initiation(criterion 1,EG1 and DG1)and Kidney Disease Improving Global Outcomes(KDIGO)classification(criterion 2,EG2 and DG2).Categorical and continuous variables were compared using the chi-squared test or Fisher’s exact test and Student’s t-test or Wilcoxon test.Kaplan-Meier curves were constructed to determine the unadjusted survival rates for the different subgroups.Results:A total of 116 patients were included in this study;of those,38 received RRT and 46 expired within 90 days.Among different strategies of RRT,there were no significant differences found in 90-day mortality(RG vs.NRG:��2=0.610,P=0.435;EG1 vs.DG1:��2=0.835,P=0.360;EG2 vs.DG2:��2=0.022,P=0.899)and renal recovery.However,the values of change in sequential organ failure assessment(ΔSOFA)max-min of patients in the EG and RG were significantly higher than those recorded in the NRG(ΔSOFA RG=7.0,ΔSOFA NRG=3.60,ΔSOFA EG1=9.00,ΔSOFA EG2=6.30;P<0.050).Also,the 90-day renal recovery in the EG was better than that noted in the DG with criterion 1(87.5%vs.38.5%,respectively,��2=10.425,P=0.032),suggesting that RRT(especially timely RRT)may be beneficial to the restoration of systemic organ function in patients with SA-AKI.Conclusion:RRT did not reduce the 90-day mortality among patients with SA-AKI.However,timely RRT may benefit the restoration of systemic organ function,thereby improving the quality of life of patients. | Yiwen Fan Liang Chen Shaowei Jiang Yingying Huang Yuxin Leng Chengjin Gao | 2022 | Journal of Intensive Medicine2022，2，3： | 2 |
| 17 | Elimination of a Retrotransposon for Quenching Genome Instability in Modern Rice显示文摘Transposable elements(TEs)constitute the most abundant portions of plant genomes and can dramatically shape host genomes during plant evolution.They also play important roles in crop domestication.However,whether TEs themselves are also selected during crop domestication has remained unknown.Here,we identify an active long terminal repeat(LTR)retrotransposon,HUO,as a potential target of selection during rice domestication and breeding.HUO is a low-copy-number LTR retrotransposon,and is active under natural growth conditions and transmitted through male gametogenesis,preferentially inserting into genomic regions capable of transcription.HUO exists in all wild rice accessions and about half of the archaeological rice grains(1200–7000 years ago)and landraces surveyed,but is absent in almost all modern varieties,indicating its gradual elimination during rice domestication and breeding.Further analyses showed that HUO is subjected to strict gene silencing through the RNA-directed DNA methylation pathway.Our results also suggest that multiple HUO copies may trigger genomic instability through altering genome-wide DNA methylation and small RNA biogenesis and changing global gene expression,resulting in decreased disease resistance and yield,coinciding with its elimination during rice breeding.Together,our study suggests that negative selection of an active retrotransposon might be important for genome stability during crop domestication and breeding. | Yu Peng Yingying Zhang Yijie Gui Dong An Junzhong Liu Xun Xu Qun Li Junmin Wang Wen Wang Chunhai Shi Longjiang Fan Baorong Lu Yiwen Deng Sheng Teng Zuhua He | 2019 | Molecular Plant2019，12，10： | 2 |
| 18 | Expressions of MAGE-A10 and MAGE-A11 in breast cancers and their prognostic significance: a retrospective clinical study显示文摘 | Yishui Lian Meixiang Sang Chunyan Ding Xinliang Zhou Xiaojie Fan Yingying Xu Weihua Lü Baoen Shan | 2012 | Journal of Cancer Research and Clinical Oncology2012，，： | 2 |
| 19 | Rapid determination of phthalate esters in alcoholic beverages by conventional ionic liquid dispersive liquid–liquid microextraction coupled with high performance liquid chromatography显示文摘 | Yingying Fan Shuhui Liu Qilong Xie | 2014 | Talanta2014，，： | 2 |
| 20 | Experimental study on filtration performance of the moving bed granular filter with axial flow显示文摘The filtration performance of the moving bed granular filter with axial flow (MBGF-AF) is investigated through a large cold experiment. The effect of different operation parameters on the filtration performance (collection efficiency, pressure drop) of the axial-flow moving bed filter is investigated in combination with the dust deposition effect and the mechanism of trapping dust by the capturing particles. The results show that the collection efficiency of MBGF-AF is enhanced by decreasing the superficial gas velocity, increasing the inlet dust concentration properly, or decreasing the moving velocity of the capturing particles. A model covering the above operation parameters is established to calculate the collection efficiency of the moving bed granular filter. It is used in a wide range of operating parameters for the MBGFs. | Han Lv Yuxue Liu Yingying Dong Yiping Fan Chunxi Lu | 2023 | Particuology2023，，1： | 2 |
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