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| 1 | Assessing the impacts of climate variability and human activities on streamflow in the water' source area of Baiyangdian Lake显示文摘作为在北方中国平原(NCP ) 的最大的沼泽地,拜伊昂达恩·莱克在维持水平衡和 NCP 的生态的健康起一个重要作用。在过去几十年,在与气候可变性和人的活动联系的 Baiyangdian 盆的减少的流速及流水量引起了一系列水和 eco 环境的问题。在这研究,我们确定了水里的流速及流水量上的气候可变性和人的活动的影响采购拜伊昂达恩·莱克的区域,基于从 1960 ~ 2008 的上面的 Tanghe 河集水(Baiyangdian 盆的亚盆) 的 hydrologic 变化的分析。气候弹性方法和水文学建模方法被用来区分气候可变性和人的活动的效果。结果证明年度流速及流水量显著地减少了(P > 0.05 ) 在 1.7, mm/a 和一个突然的变化在一年 1980 附近被识别。quantification 结果显示气候变化说明了减少的流速及流水量的 38%40% ,当人的活动说明了 60%62% 时。因此,人的活动的效果在拜伊昂达恩·莱克的水来源区域在流速及流水量的衰落上起了一个主导的作用。把生态系统作为拜伊昂达恩·莱克的健康,我们建议最小的生态的水需求和综合分水岭管理以后应该被保证。 | HU Shanshan LIU Changming ZHENG Hongxing WANG Zhonggen YU Jingjie | 2012 | Journal of Geographical Sciences2012，22，5： | 15 |
| 2 | GSA:Genome Sequence Archive显示文摘With the rapid development of sequencing technologies towards higher throughput and lower cost, sequence data are generated at an unprecedentedly explosive rate. To provide an efficient and easy-to-use platform for managing huge sequence data, here we present Genome Sequence Archive(GSA; http://bigd.big.ac.cn/gsa or http://gsa.big.ac.cn), a data repository for archiving raw sequence data. In compliance with data standards and structures of the International Nucleotide Sequence Database Collaboration(INSDC), GSA adopts four data objects(Bio Project, Bio Sample,Experiment, and Run) for data organization, accepts raw sequence reads produced by a variety of sequencing platforms, stores both sequence reads and metadata submitted from all over the world,and makes all these data publicly available to worldwide scientific communities. In the era of big data, GSA is not only an important complement to existing INSDC members by alleviating the increasing burdens of handling sequence data deluge, but also takes the significant responsibility for global big data archive and provides free unrestricted access to all publicly available data in support of research activities throughout the world. | Yanqing Wang Fuhai Song Junwei Zhu Sisi Zhang Yadong Yang Tingting Chen Bixia Tang Lili Dong Nan Ding Qian Zhang Zhouxian Bai Xunong Dong Huanxin Chen Mingyuan Sun Shuang Zhai Yubin Sun Lei Yu Li Lan Jingfa Xiao Xiangdong Fang Hongxing Lei Zhang Zhang Wenming Zhao | 2017 | Genomics, Proteomics & Bioinformatics2017，15，1： | 13 |
| 3 | Malus-metasurface-assisted polarization multiplexing显示文摘Polarization optics plays a pivotal role in diffractive,refractive,and emerging flat optics,and has been widely employed in contemporary optical industries and daily life.Advanced polarization manipulation leads to robust control of the polarization direction of light.Nevertheless,polarization control has been studied largely independent of the phase or intensity of light.Here,we propose and experimentally validate a Malus-metasurface-assisted paradigm to enable simultaneous and independent control of the intensity and phase properties of light simply by polarization modulation.The orientation degeneracy of the classical Malus’s law implies a new degree of freedom and enables us to establish a one-to-many mapping strategy for designing anisotropic plasmonic nanostructures to engineer the Pancharatnam–Berry phase profile,while keeping the continuous intensity modulation unchanged.The proposed Malus metadevice can thus generate a near-field greyscale pattern,and project an independent far-field holographic image using an ultrathin and single-sized metasurface.This concept opens up distinct dimensions for conventional polarization optics,which allows one to merge the functionality of phase manipulation into an amplitudemanipulation-assisted optical component to form a multifunctional nano-optical device without increasing the complexity of the nanostructures.It can empower advanced applications in information multiplexing and encryption,anti-counterfeiting,dual-channel display for virtual/augmented reality,and many other related fields. | Liangui Deng Juan Deng Zhiqiang Guan Jin Tao Yang Chen Yan Yang Daxiao Zhang Jibo Tang Zhongyang Li Zile Li Shaohua Yu Guoxing Zheng Hongxing Xu Cheng-Wei Qiu Shuang Zhang | 2020 | Light(Science & Applications)2020，9，1： | 7 |
| 4 | Cloning of catalase and expression patterns of catalase and selenium-dependent glutathione peroxidase from Exopalaemon carinicauda in response to low salinity stress显示文摘Catalase(CAT) and selenium-dependent glutathione peroxidase(Se-GPx) play a vital role in protecting organisms against various oxidative stresses by eliminating H2O2. The objective of this paper is to evaluate the roles of these antioxidant molecules in the ridgetail white prawn Exopalaemon carinicauda in response to low salinity stress. A complementary DNA(cDNA) containing the complete coding sequence of CAT was cloned from the hepatopancreas using reverse-transcription polymerase chain reaction(RT-PCR) and rapid amplification of cDNA ends. The full-length cDNA of CAT(2 649 bp) contains a 5'-untranslated region(UTR) of 78 bp, a 3'- UTR of1 017 bp, with a poly(A) tail, and an open reading frame of 1 554 bp encoding a 517-amino-acid polypeptide with predicted molecular mass of 58.46 kDa and estimated isoelectric point of 6.64. This CAT sequence contained the proximal active site signature(60FDRERIPERVVHAKGAG76), proximal heme-ligand signature sequence(350RLFSYPDTH358) and three catalytic amino acid residues(His71, Asn144 and Tyr354). Sequence comparison showed that the CAT deduced amino acid sequence of E. carinicauda shared 68%-92% of identities with those of other species. Quantitative real-time PCR analysis revealed that CAT m RNA was widely expressed in the hepatopancreas(highest), hemocyte, eyestalk, heart, gill, muscle, ovary and stomach. Under low salinity stress,CAT and GPx m RNA expression levels both in the gill and hepatopancreas increased significantly at the first 48 h and 6 h respectively, indicating a tissue- and time-dependent antioxidant response in E. carinicauda. All these results indicate that E. carinicauda CAT is a member of the CAT family and might be involved in the acute response against low salinity stress. | REN Hai LI Jian LI Jitao YING Yu GE Hongxing LI Dongli YU Tianji | 2015 | Acta Oceanologica Sinica2015，34，8： | 6 |
| 5 | Siting of Dark Sky Reserves in China Based on Multi-source Spatial Data and Multiple Criteria Evaluation Method显示文摘With the rapid development of population and urbanization and the progress of lighting technology, the influence of artificial light sources has increased.In this context, the problem of light pollution has attracted wide attention.Previous studies have revealed that light pollution can affect biological living environments, human physical and mental health, astronomical observations and many other aspects.Therefore, organizations internationally have begun to advocate for measures to prevent light pollution, many of which are recognized by the International Dark-Sky Association(IDA).In addition to improving public awareness, legal protections, technical treatments and other means, the construction of Dark Sky Reserves(DSR) has proven to be an effective preventive measure.So far, as a pioneer practice in this field, the IDA has identified 11 DSRs worldwide.Based on the DA requirements for DSRs, this paper utilizes NPP-VIIRS nighttime light data and other multi-source spatial data to analyze possible DSR sites in China.The land of China was divided into more than ten thousand 30 km × 30 km fishnets, and constraint and suitable conditions were designated, respectively, as light and cloud conditions, and scale, traffic and attractiveness conditions.Using a multiple criteria evaluation, 1443 fishnets were finally selected as most suitable sites for the construction of DSRs.Results found that less than 25% of China is not subject to light pollution, and less than 13% is suitable for DSR construction, primarily in western and northern areas, including Tibet, Xinjiang, Qinghai, Gansu and Inner Mongolia. | WEI Ye CHEN Zuoqi XIU Chunliang YU Bailang LIU Hongxing | 2019 | Chinese Geographical Science2019，29，6： | 5 |
| 6 | Reversing cold tumors to hot: An immunoadjuvant-functionalized metalorganic framework for multimodal imaging-guided synergistic photoimmunotherapy显示文摘Immunotherapy assays using immunoadjuvants and tumor antigens could greatly increase the survival rates of patients with malignant tumors.As effective carriers,metal-organic frameworks(MOFs)have been widely utilized in cancer therapy due to their remarkable histocompatibility and low toxicity.Herein,we constructed a multimodal imaging-guided synergistic cancer photoimmunotherapy by employing a specific MOF(MIL101-NH2)as the core carrier;the MOF was dual-dressed with photoacoustic and fluorescent signal donors(indocyanine green,ICG)and immune adjuvants(cytosine-phosphate-guanine sequence,CpG)and named ICGCpG@MOF.This nanocarrier could passively target the tumor site through the EPR effect and achieve multimodal imaging(fluorescence,photoacoustic,photothermal and magnetic resonance imaging)of the tumor.Synergistic cancer photoimmunotherapy was achieved via simultaneous photodynamic and photothermal methods with 808 nm laser irradiation.ICG-CpG@MOF achieved the GSH-controlled release of immunoadjuvant into the tumor microenvironment.Furthermore,the released tumor-associated antigen along with CpG could induce the transformation of tumor cells from cold to hot by activating the immune system,which significantly enhanced tumor cytotoxicity and achieved high cure rates with minimal side-effects.This strategy utilizing multimodal imaging and synergistic cancer photoimmunotherapy provides a promising approach for the diagnosis and treatment of cancer. | Zhijin Fan Hongxing Liu Yaohua Xue Jingyan Lin Yu Fu Zhaohua Xia Dongming Pan Jian Zhang Kun Qiao Zhenzhen Zhang Yuhui Liao | 2021 | Bioactive Materials2021，6，2： | 4 |
| 7 | Parameter Selection Method for SVM with PSO显示文摘 | PENG Xiyuan WU Hongxing PENG Yu | 2006 | Chinese Journal of Electronics2006，15，4： | 4 |
| 8 | The information content of rules and rule sets and its application显示文摘The information content of rules is categorized into inner mutual information con-tent and outer impartation information content. Actually, the conventional objective interestingness measures based on information theory are all inner mutual infor-mation, which represent the confidence of rules and the mutual information be-tween the antecedent and consequent. Moreover, almost all of these measures lose sight of the outer impartation information, which is conveyed to the user and help the user to make decisions. We put forward the viewpoint that the outer impartation information content of rules and rule sets can be represented by the relations from input universe to output universe. By binary relations, the interaction of rules in a rule set can be easily represented by operators: union and intersection. Based on the entropy of relations, the outer impartation information content of rules and rule sets are well measured. Then, the conditional information content of rules and rule sets, the independence of rules and rule sets and the inconsistent knowledge of rule sets are defined and measured. The properties of these new measures are discussed and some interesting results are proven, such as the information con-tent of a rule set may be bigger than the sum of the information content of rules in the rule set, and the conditional information content of rules may be negative. At last, the applications of these new measures are discussed. The new method for the appraisement of rule mining algorithm, and two rule pruning algorithms, λ-choice and RPCIC, are put forward. These new methods and algorithms have predominance in satisfying the need of more efficient decision information. | HU Dan LI HongXing YU XianChuan | 2008 | Science in China(Series F)2008，51，12： | 3 |
| 9 | Analysis of the Prevalence and Situation of Myopia in Adolescents from South China显示文摘Purpose: To conduct dynamic detection of refraction changes in adolescents with myopia and analyze the correlation between different reexamination times and factors that included age of onset, initial refractive power, and rate of myopia progression.Methods: A total of 900 adolescents(aged 6-15 years) with myopia admitted to Zhongshan Ophthalmic Center between2009 and 2013 were randomly selected in this investigation.All participants underwent objective refraction measurement with an autorefractometer(Topcon 8900) or streak retinoscopy and subjective refraction detection with an autorefractor(Nidek).or minus-lens procedures at different time intervals(6months, 1, and 2 years). Accurate refractive power was obtained..All data were analyzed with SPSS 18.0 statistical software.Results:.The mean refractive power was increased by 0.56 ±0.37 diopters(D) after 6 months,.by 0.83±0.45 D after 1 year,.and by 1.50±0.70 D after 2 years..Among the 900 adolescents,.the most rapid increase in refractive power was observed at the age of 8 years at the 6-month reexamination, at the age of8 and 9 years at the 1-year reexamination,.and at the age of 7-9 years at the 2-year reexamination..The increase in index of refraction tended to diminish with aging..The different cycles of reexamination revealed a slowing of the rate of myopia progression along with the increase in the initial index of refraction..The highest rate of myopia progression was noted in low-myopic adolescents with initial refractive power ranging from-0.25 to 2.75 D.Conclusion:.No positive correlation was documented between different cycles of reexamination and the refractive power. The increase in refractive power was associated with factors that included the reexamination cycle, age of onset, and initial refractive power. | Shuiming Yu Hongxing Diao Junwen Zeng | 2015 | Eye Science2015，30，2： | 3 |
| 10 | Further understanding of an uncommon disease of combined small cell lung cancer: clinical features and prognostic factors of 114 cases显示文摘Objective: Combined small cell lung cancer(C-SCLC) is an uncommon subgroup of small cell lung cancer(SCLC) and few clinical data can be referred.Our study is to investigate the clinical features and prognostic factors of C-SCLC, as well as the role of multimodality treatment.Methods: Between January 2004 and December 2012, patients with histologically diagnosed C-SCLC were retrospectively analyzed.The survivals were evaluated with the Kaplan-Meier method.Univariate and multivariate analyses were used to evaluate potential prognostic factors.Results: One hundred and fourteen patients were enrolled, with a median age of 59(range: 20-79) years old.The most common combined component was squamous cell carcinoma(52.6%).Among these patients, the disease was stage Ⅰ, Ⅱ, Ⅲ and Ⅳ in 9.6%, 19.3%, 46.5% and 24.6% of the patients, respectively.Eighty patients(70.2%)received at least two of the three modalities containing chemotherapy, radiotherapy and surgery.The median follow-up was 32.5 months.The median time of overall survival(OS) was 26.2 months.On univariate analysis,smoking(P=0.029), Karnofsky performance score(KPS) <80(P=0.000), advanced TNM stage(P=0.000), no surgery(P=0.010), positive resection margin(P=0.000), positive lymph nodes ≥4(P=0.000), positive lymph node ratio >10%(P=0.000) and non-multimodality treatment(P=0.004) were associated with poor OS.Multivariate analysis confirmed that smoking, advanced TNM stage, positive resection margin and positive lymph nodes ratio>10% were poor prognostic features.Conclusions: C-SCLC has a relatively early stage and good prognosis, which may due to the underestimated diagnosis in non-surgical patients.Multimodality therapy is recommended, especially for limited disease.Smoking,advanced TNM stage, positive resection margin and positive lymph nodes ratio >10% are poor prognostic factors. | Yu Men Zhouguang Hui Jun Liang Qinfu Feng Dongfu Chen Hongxing Zhang Zefen Xiao Zongmei Zhou Weibo Yin Luhua Wang | 2016 | Chinese Journal of Cancer Research2016，28，5： | 2 |
| 11 | THEORY AND EXPERIMENT ON THE VISCOUS HEATING OF FLUID DAMPER UNDER SHOCK ENVIRONMENT显示文摘A specially designed fluid damper used as negative shock pulse generator in the shock resistance test system to dissipate the shock input energy in transient time duration is presented.The theoretical modeling based on the three-dimensional equation of heat transfer through a fluid element is created to predict the viscous heating in the fluid damper under shock conditions.A comprehensive experimental program that investigates the problem of viscous heating in the fluid damper under different shock conditions is conducted on the shock test machine to validate the analytical expression.Temperature histories for the fluid within the damper at two locations,the annular-orifice and the-end-of stroke of the damper,are recorded.The experimental results show that the theoretical modal can offer a very dependable prediction for the temperature histories in the damper for increasing input velocity.The theoretical model and experimental data both clearly indicate that the viscous heating in the damper is directly related to the maximum shock velocity input and the pressure between the two sides of the piston head. | CHU Deying ZHANG Zhiyi WANG Gongxian HUA Hongxing WANG Yu | 2008 | Chinese Journal of Mechanical Engineering2008，21，3： | 2 |
| 12 | Tolerance evaluation of rice varieties to the brown planthopper,Nilaparvata lugens feeding显示文摘The brown planthopper, Nilaparvata lugens (Stal) (BPH) is one of the most important insect pests of rice in China and other east-southern Asian countries. | CHEN Jianming YU Xiaoping LU Zhongxian ZHENC Xusong Xu Hongxing,Inst of Plant Protection,Zhejiang Acad of Agri Sci,Hangzhou 310021 CHENG Jia ’an,Dept of Plant Protection,Zhejiang Univ,Hangzhou 310029,China | 2002 | Chinese Rice Research Newsletter2002，10，3： | 2 |
| 13 | Detection of Asymptomatic Carotid Artery Stenosis in High-Risk Individuals of Stroke Using a Machine-Learning Algorithm显示文摘Objective Asymptomatic carotid stenosis(ACS)is closely associated to the incidence of severe cerebrovascular diseases.Early identifying the individuals with ACS and its associated risk factors could be beneficial for primary prevention of stroke.This study aimed to investigate a machine-learning algorithm for the detection of ACS among high-risk population of stroke based on the associated risk factors.Methods A novel model of machine learning was utilized to screen the associated predictors of ACS based on 30 potential risk factors.The algorithm of this model adopted a random forest pattern based on the training data and then was verified using the testing data.All of the original data were retrieved from the China National Stroke Screening and Prevention Project(CNSSPP),including demographic,clinical and laboratory characteristics.The individuals with high risk of stroke were enrolled and randomly divided into a training group and a testing group at a ratio of 4:1.The identification of carotid stenosis by carotid artery duplex scans was set as the golden standard.The receiver operating characteristic(ROC)curve and the area under the curve(AUC)was used to evaluate the efficacy of the model in detecting ACS.Results Of 2841 high risk individual of stroke enrolled,326(11.6%)were diagnosed as ACS by ultrasonography.The top five risk fectors contributing to ACS in this model were identified as family history of dyslipidemia,high level of lowdensity lipoprotein cholesterol(LDL-c),low level of high-density lipoprotein cholesterol(HDL-c),aging,and low body. | Junxiong Yin Cheng Yu Lixia Wei Chuanyong Yu Hongxing Liu Mingyang Du Feng Sun Chongjun Wang Xiaoshan Wang | 2020 | Chinese Medical Sciences Journal2020，35，4： | 2 |
| 14 | A new Z-epicanthoplasty and a concomitant double eyelidplasty in Chinese eyelids显示文摘 | Haiming Zhang Hongxing Zhuang Hao Yu | 2006 | Plast Reconstr Surg2006，118，4： | 1 |
| 15 | Reflooding Characteristics Investigation and Predicted Models Improvement for the Pressurized Water Reactor with the Tight Lattice Core Design 显示文摘 | Dan Wu Hongxing Yu Junchong Yu | 2012 | Nuclear Engineering and Design2012，249，： | 1 |
| 16 | Realization of embed- ded multimedia system based on dual-core processor OMAP5910 显示文摘 | PENG Li LU Yu WEI Hongxing | 2008 | Computational Engineering in Systems Applications( CESA)2008，，5： | 1 |
| 17 | Technical innovations in ear reconstruction using a skin expander with autogenous cartilage grafts显示文摘 | Yu Dashan Jiang Haiyue Yang Qinghua Pan Bo Lin Lin Wang Tailing Wang Yanmei Qin Xiao Zhuang Hongxing | 2008 | Journal of Plastic, Reconstructive & Aesthetic Surgery2008，，： | 1 |
| 18 | Modeling and simulating for two dimensional infrared photonic crystal devices显示文摘 | Zheng Hongxing Yu Daoyin | 2004 | Int J Infrared Millimeter Waves2004，25，4： | 1 |
| 19 | Effect of AETiO 3 (AE=Mg, Ca, Sr) doping on dielectric and varistor characteristics of CaCu 3 Ti 4 O 12 ceramic prepared by the sol–gel process显示文摘 | Dong Xu Kai He Renhong Yu Lei Jiao Hongming Yuan Xiujuan Sun Guoping Zhao Hongxing Xu Xiaonong Cheng | 2014 | Journal of Alloys and Compounds2014，，： | 1 |
| 20 | Realizatio,1 of embedded multilnedia system based on dual-core processor OMAP5910 显示文摘 | Peng Li Yu Lu Wei Hongxing | 2008 | Computational Engineering in Systems Applications (CESA)2008，，4： | 1 |
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