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| 1 | Effect of viscosity,basicity and organic content of composite flocculant on the decolorization performance and mechanism for reactive dyeing wastewater显示文摘A coagulation/flocculation process using the composite flocculant polyaluminum chloride-epichlorohydrin dimethylamine (PACEPI-DMA) was employed for the treatment of an anionic azo dye (Reactive Brilliant Red K-2BP dye).The effect of viscosity (η),basicity (B=[OH]/[Al]) and organic content (WP) on the flocculation performance as well as the mechanism of PAC-EPI-DMA flocculant were investigated.The η was the key factor affecting the dye removal efficiency of PAC-EPI-DMA.PAC-EPI-DMA with an intermediate η (2400 mPa·sec) gave higher decolorization efficiency by adsorption bridging and charge neutralization due to the co-effect of PAC and EPI-DMA polymers.The W P of the composite flocculant was a minor important factor for the flocculation.The adsorption bridging of PAC-EPI-DMA with η of 300 or 4300 mPa·sec played an important role with the increase of W P,whereas the charge neutralization of them was weaker with the increase of W P.There was interaction between W P and B on the removal of reactive dye.The composite flocculant with intermediate viscosity and organic content was effective for the treatment of reactive dyeing wastewater,which could achieve high reactive dye removal efficiency with low organic dosage. | Yuanfang Wang Baoyu Gao Qinyan Yue Yan Wang | 2011 | Journal of Environmental Sciences2011，23，10： | 33 |
| 2 | Preoperative neutrophil-to-lymphocyte ratio plus platelet-to-lymphocyte ratioin predicting survival for patients with stage Ⅰ-Ⅱgastric cancer显示文摘Background:The preoperative neutrophil-to-lymphocyte ratio(NLR) and the platelet-to-lymphocyte ratio(PLR) are associated with poor prognosis of gastric cancer.We aimed to determine whether the combination of NLR and PLR(NLR-PLR) could better predict survival of patients after curative resection for stage Ⅰ-Ⅱ gastric cancer.Methods:We collected data from the medical records of patients with stage Ⅰ-Ⅱ gastric cancer undergoing curative resection between December 2000 and November 2012 at the Sun Yat-sen Cancer Center.The preoperative NLRPLR was calculated as follows:patients with both elevated NLR(≥2.1) and PLR(≥ 120) were given a score of 2,and patients with only one or neither were given a score of 1 or 0,respectively.Results:Kaplan-Meier analysis and log-rank tests revealed significant differences in overall survival(OS) among patients with NLR-PLR scores of 0,1 and 2(P < 0.001).Multivariate analysis showed that OS was independently associated with the NLR-PLR score[hazard ratio(HR) = 1.51,95%confidence interval(CI) 1.02-2.24,P = 0.039]and TNM stage(HR = 1.36,95%CI 1.01-1.83,P= 0.041).However,other systemic inflammation-based prognostic scores,including the modified Glasgow prognostic score,the prognostic nutritional index,and the combination of platelet count and NLR,were not.In TNM stage-stratified analysis,the prognostic significance of NLR-PLR was maintained in patients with stage Ⅰ(P < 0.001) and stage Ⅱ cancers(P= 0.022).In addition,the area under the receiver operating characteristic curve for the NLR-PLR score was higher than those of other systemic inflammation-based prognostic scores(P = 0.001).Conclusion:The preoperative NLR-PLR score is a useful predictor of postoperative survival in the patients with stage l-ll gastric cancer and may help identify high-risk patients for rational therapy and timely follow-up. | Xiaowei Sun Xuechao Liu Jianjun Liu Shangxiang Chen Dazhi Xu Wei Li Youqing Zhan Yuanfang Li Yingbo Chen Zhiwei Zhou | 2016 | Chinese Journal of Cancer2016，35，7： | 25 |
| 3 | One-step synthesis of fluorescent hydroxyls-coated carbon dots with hydrothermal reaction and its application to optical sensing of metal ions显示文摘Carbon dots (CDs) with average diameter of 3.1 ± 0.5 nm were facilely synthesized with candle soot through hydrothermal reaction in sodium hydroxide aqueous solution. The as-prepared CDs were covered with a lot of hydroxyls, possessed properties of good water-solubility, anti-photobleaching, salt tolerance, and low cytotoxicity, and had a fluorescence quantum yield (QY) of about 5.5%. The fluorescence of the hydroxyls-coated CDs could be selectively quenched by metal ions such as Cr3+, Al3+ and Fe3+, which is because these metals can easily combine with the hydroxyl groups on the surface of CDs and induce aggregation of hydroxyls-coated CDs. Experiments showed that the quenching of Cr3+ had a Sterm-Volmer constant of 1.03 × 107 M-1 with a liner range of 1.0-25.0 μM and detection limit of 60 nM (3σ). | LIU LiQin LI YuanFang ZHAN Lei LIU Yue HUANG ChengZhi | 2011 | Science China Chemistry2011，54，8： | 21 |
| 4 | Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma显示文摘Esophageal squamous cell carcinoma(ESCC)is a poor-prognosis cancer type with limited understanding of its molecular etiology.Using 508 ESCC genomes,we identified five novel significantly mutated genes and uncovered mutational signature clusters associated with metastasis and patients’outcomes.Several functional assays implicated that NFE2L2 may act as a tumor suppressor in ESCC and that mutations in NFE2L2 probably impaired its tumor-suppressive function,or even conferred oncogenic activities.Additionally,we found that the NFE2L2 mutations were significantly associated with worse prognosis of ESCC.We also identified potential noncoding driver mutations including hotspot mutations in the promoter region of SLC35E2 that were correlated with worse survival.Approximately 5.9%and 15.2%of patients had high tumor mutation burden or actionable mutations,respectively,and may benefit from immunotherapy or targeted therapies.We found clinically relevant coding and noncoding genomic alterations and revealed three major subtypes that robustly predicted patients’outcomes.Collectively,we report the largest dataset of genomic profiling of ESCC useful for developing ESCC-specific biomarkers for diagnosis and treatment. | Yongping Cui Hongyan Chen Ruibin Xi Heyang Cui Yahui Zhao Enwei Xu Ting Yan Xiaomei Lu Furong Huang Pengzhou Kong Yang Li Xiaolin Zhu Jiawei Wang Wenjie Zhu Jie Wang Yanchun Ma Yong Zhou Shiping Guo Ling Zhang Yiqian Liu Bin Wang Yanfeng Xi Ruifang Sun Xiao Yu Yuanfang Zhai Fang Wang Jian Yang Bin Yang Caixia Cheng Jing Liu Bin Song Hongyi Li Yi Wang Yingchun Zhang Xiaolong Cheng Qimin Zhan Yanhong Li Zhihua Liu-Show | 2020 | Cell Research2020，30，10： | 19 |
| 5 | Simulating the Effect of Hydrate Dissociation on Wellhead Stability During Oil and Gas Development in Deepwater显示文摘It is well known that methane hydrate has been identified as an alternative resource due to its massive reserves and clean property. However, hydrate dissociation during oil and gas development(OGD) process in deep water can affect the stability of subsea equipment and formation. Currently, there is a serious lack of studies over quantitative assessment on the effects of hydrate dissociation on wellhead stability. In order to solve this problem, ABAQUS finite element software was used to develop a model and to evaluate the behavior of wellhead caused by hydrate dissociation. The factors that affect the wellhead stability include dissociation range, depth of hydrate formation and mechanical properties of dissociated hydrate region. Based on these, series of simulations were carried out to determine the wellhead displacement. The results revealed that, continuous dissociation of hydrate in homogeneous and isotropic formations can causes the non-linear increment in vertical displacement of wellhead. The displacement of wellhead showed good agreement with the settlement of overlying formations under the same conditions. In addition, the shallower and thicker hydrate formation can aggravate the influence of hydrate dissociation on the wellhead stability. Further, it was observed that with the declining elastic modulus and Poisson's ratio, the wellhead displacement increases. Hence, these findings not only confirm the effect of hydrate dissociation on the wellhead stability, but also lend support to the actions, such as cooling the drilling fluid, which can reduce the hydrate dissociation range and further make deepwater operations safer and more efficient. | LI Qingchao CHENG Yuanfang ZHANG Huaiwen YAN Chuanliang LIU Yuwen | 2018 | Journal of Ocean University of China2018，17，1： | 11 |
| 6 | The program structure designing and optimizing tests of GRAPES physics显示文摘According to the modularization and standardization of program structure in Global/Regional Assimilation and Prediction System (GRAPES), the plug-compatible and transplantable regional meso-scale and global middle-range physics software package is established. The package's component integrality is comparative with the other advanced models physics. A three-level structure of connecting GRAPES physics and dynamic frame has been constructed. The friendly interface is designed for users to plug in their own physics packages. Phenomenon of grid-point storm rainfall in numerical prediction is analyzed with the numerical tests. The scheme of air vertical velocity calculation is improved. Optimizing tests of physics schemes are performed with the correlative parameters adjusting. The results show that the false grid-point storm rainfall is removed by precipitation scheme improving. Then the score of precipitation forecast is enhanced. | XU GuoQiang CHEN DeHui XUE JiShan SUN Jian SHEN XueShun SHEN YuanFang HUANG LiPing WU XiangJun ZHANG HongLiang WANG ShiYu | 2008 | Chinese Science Bulletin2008，53，22： | 11 |
| 7 | A new-generation sand and dust storm forecasting system GRAPES_CUACE/Dust:Model development,verification and numerical simulation显示文摘Based on the new-generation Global/Regional Assimilation and PrEdiction System(GRAPES) developed by the Numerical Prediction Research Center,China Meteorological Administration and the Chinese Unified Atmospheric Chemistry Environment for Dust Atmospheric Chemistry Module(CUACE/Dust) developed by the Centre for Atmosphere Watch and Services(CAWAS) of the Chinese Academy of Meteorological Sciences(CAMS) ,the China sand and dust storm forecasting system GRAPES /CUACE-Dust model has been established.The latest data of land desertification,optical properties of China sand and dust aerosols,daily soil moisture and snow cover over China main land was introduced in this system.The system showed good performance in mass conservation.The comparisons of real-time prediction outputs with surface observations and aerosol indices derived from TOMS ozone spectrophotometers(TOMS AI) indicate that the model can predict the outbreak,development,transport and depletion processes of sand and dust storms accurately over China and the East Asian region.The system makes real-time quantitative prediction of a series of elements including sand and dust injection from the surface,dry and wet deposition amount,dust concentration and optical depth.We selected 7 major dust storms occurring in April 2006 and analyzed the spatiotemporal distribution patterns of dust emission,dry and wet deposition and atmospheric load in this paper.The results showed that about 225 million tons of dust were emitted into the atmosphere from the deserts over east Asia in that month.The 3 major sand and dust sources were just as the following:The deserts in northern Inner Mongolia and the boundary area around China-Mongolia were the first dust sources with a contribution of 153 million tons accounting for 68%of the total emission.The Taklimakan Desert ranked second and contributed approximately 40 million tons accounting for 17%of the dust emission.The Onqin Daga Sandland emitted about 15 million tons or 7%of the total emission.The contributions from other deserts,sandy lands and abandoned farmlands were about only 8%of the total dust emission.The total deposition over the East Asian region in April 2006 was 136 million tons.The regional distribution of dust deposition showed that the 3 major sources were also the major deposition areas.The deposition amount in the 3 major sources accounted for 78%of the total with about 135 million tons falling back to the source regions.The secondary deposition area was the China mainland downriver,where more than 2 million tons deposited accounting for 16%of the total deposition.The deposition over the region east of 120°E including China off-shore regions,Korean Peninsula,Japan and the West Pacific took only 6%of the total deposition,which was about 850000 tons.The analysis on dry and wet deposition showed that dry deposition dominated in the process,accounting for 94%of the total sand and dust depositions in the period and wet deposition only was around for 6%,since it was generally dry with less rainfall over northern China in April. | WANG Hong GONG ShanLing ZHANG HongLiang CHEN Yong SHEN XueShun CHEN DeHui XUE JiShan SHEN YuanFang WU XiangJun JIN ZhiYan | 2010 | Chinese Science Bulletin2010，55，7： | 10 |
| 8 | A flexible capacitive tactile sensor array with micro structure for robotic application显示文摘A flexible capacitive tactile sensor array with micro needle structure is proposed in this paper for robotic application.Micro needle layer made of polydimethylsiloxane(PDMS)is sandwiched between the upper electrode layer made of PDMS and the bottom electrode layer fabricated on polyester(PET)film.The PDMS material renders the device adequate flexibility as it can be rolled into a cylinder.The single cell size in the fabricated 4×4 sensors array is 0.7×0.5 cm2and the initial capacitance of each cell is 0.86 p F.The fabricated cell shows a sensitivity of 3.26%/m N within the full scale range of 1 k Pa.The micro needle structure gives better repeatability and stability.The maximum error during each measurement is about 3.2%,while the minimum error is about 1.2%. | HU XiaoHui ZHANG Xu LIU Ming CHEN YuanFang LI Peng PEI WeiHua ZHANG Chun CHEN HongDa | 2014 | Science China(Information Sciences)2014，57，12： | 9 |
| 9 | Fe_3O_4@C nanoparticles as high-performance Fenton-like catalyst for dye decoloration显示文摘Water pollution has become serious environmental problem nowadays. Advanced oxidation processes(AOP) have been widely applied in water treatment.However, traditional Fenton reaction based on Fe2﹢-H2O2 system has obvious drawbacks, which limit its applications In this study, magnetic Fe3O4core-C shell nanoparticles(Fe3O4@C NPs) were prepared for the decoloration of methylene blue(MB) via the co-precipitation followed by the hydrothermal dehydrogenation of glucose. Fe3O4@C NPs showed high catalytic activity of the decoloration of MB through the decomposition of H2O2 in Fenton-like reactions. Fe3O4@C NPs had much higher activity than bare Fe3O4 cores, suggesting the coating of carbon enhanced the catalytic activity. The performance of Fe3O4@C NPs was better at lower pH and higher temperature, but was significantly inhibited in the presence of radical scavenger tertiary butanol. Fe3O4@C NPs could be magnetic separated and regenerated, and maintained with very good catalytic activity. The implication for the applications of Fe3O4@C NP-catalyzed Fenton-like reactions in water treatment was discussed. | Xiaoliang Zhang Manli He Jia-Hui Liu Rong Liao Lianqin Zhao Jingru Xie Ruijue Wang Sheng-Tao Yang Haifang Wang Yuanfang Liu | 2014 | Chinese Science Bulletin2014，59，27： | 8 |
| 10 | Applying a statistical method to streamflow reduction caused by underground mining for coal in the Kuye River basin显示文摘Streamflow in the Kuye River basin has been sharply reduced by the effects of climate change and human activities.Since 1997,the intensification of coal mining has resulted in substantial reductions to streamflow alongside an ever-increasing demand for water.In this study,we present a derived statistical method,incorporating the Mann-Kendall and Pettitt method(MK-P) and the Soil and Water Assessment Tool(SWAT),and apply it to estimating the streamflow reductions caused by underground mining for coal in the Kuye River basin.The results show that underground mining is an important cause of the streamflow reductions observed since1997,being responsible for reductions of 21.15 mm/yr(~56%of the total) during 1997-2009.The results of the SWAT simulation were assessed by several performance criteria:Nash-Suttcliffe Efficiency(Nse),correlation coefficient(R^2),relative error(RE),P-factor and Pv-factor.The close match between the simulations and observed data supports the reasonability of our findings.We suggest that engineering strategies be adopted to limit streamflow loss into goafs via fractured zones in the coalfield. | LI Shu CHEN YuanFang LI ZhiJia ZHANG Ke | 2016 | Science China(Technological Sciences)2016，59，12： | 8 |
| 11 | Numerical Analysis of Wellbore Instability in Gas Hydrate Formation During Deep-Water Drilling显示文摘Gas hydrate formation may be encountered during deep-water drilling because of the large amount and wide distribution of gas hydrates under the shallow seabed of the South China Sea. Hydrates are extremely sensitive to temperature and pressure changes, and drilling through gas hydrate formation may cause dissociation of hydrates, accompanied by changes in wellbore temperatures, pore pressures, and stress states, thereby leading to wellbore plastic yield and wellbore instability. Considering the coupling effect of seepage of drilling fluid into gas hydrate formation, heat conduction between drilling fluid and formation, hydrate dissociation, and transformation of the formation framework, this study established a multi-field coupling mathematical model of the wellbore in the hydrate formation. Furthermore, the influences of drilling fluid temperatures, densities, and soaking time on the instability of hydrate formation were calculated and analyzed. Results show that the greater the temperature difference between the drilling fluid and hydrate formation is, the faster the hydrate dissociates, the wider the plastic dissociation range is, and the greater the failure width becomes. When the temperature difference is greater than 7℃, the maximum rate of plastic deformation around the wellbore is more than 10%, which is along the direction of the minimum horizontal in-situ stress and associated with instability and damage on the surrounding rock. The hydrate dissociation is insensitive to the variation of drilling fluid density, thereby implying that the change of the density of drilling fluids has a minimal effect on the hydrate dissociation. Drilling fluids that are absorbed into the hydrate formation result in fast dissociation at the initial stage. As time elapses, the hydrate dissociation slows down, but the risk of wellbore instability is aggravated due to the prolonged submersion in drilling fluids. For the sake of the stability of the wellbore in deep-water drilling through hydrate formation, the drilling fluid with low temperatures should be given priority. The drilling process should be kept under balanced pressures, and the drilling time should be shortened. | ZHANG Huaiwen CHENG Yuanfang LI Qingchao YAN Chuanliang HAN Xiuting | 2018 | Journal of Ocean University of China2018，17，1： | 8 |
| 12 | Construction of a macromolecular structural model of Chinese lignite and analysis of its low-temperature oxidation behavior显示文摘The aim of this paper is to analyze the change in the active structure of lignite during the process of lowtemperature oxidation by constructing a molecular structure model for lignite. Using quantum computation combined with experimental results of proximate analysis, ultimate analysis, Fourier transform infrared spectroscopy(FTIR) and X-ray photoelectron spectroscopy(XPS), a structural model for the large molecular structure was constructed. By analyzing the bond lengths in the model molecule, the evolution law for the active structure of lignite was predicted for the process of low-temperature oxidation. In low-temperature oxidation,alkanes and hydroxyls are the primary active structures observed in lignite, though ether may also react. These active functional groups react with oxygen to release heat, thereby speeding up the reaction between coal and oxygen. Finally, the content of various functional groups in the process of lignite low-temperature oxidation was analyzed by infrared analysis, and the accuracy of the model was verified. | Xianliang Meng Mingqiang Gao Ruizhi Chu Zhenyong Miao Guoguang Wu Lei Bai Peng Liu Yuanfang Yan Pengcheng Zhang | 2017 | Chinese Journal of Chemical Engineering2017，25，9： | 8 |
| 13 | Relation Classification via Sequence Features and Bi-Directional LSTMs显示文摘Structure features need complicated pre-processing, and are probably domain-dependent. To reduce time cost of pre-processing, we propose a novel neural network architecture which is a bi-directional long-short-term-memory recurrent-neural-network(Bi-LSTM-RNN) model based on low-cost sequence features such as words and part-of-speech(POS) tags, to classify the relation of two entities. First, this model performs bi-directional recurrent computation along the tokens of sentences. Then, the sequence is divided into five parts and standard pooling functions are applied over the token representations of each part. Finally, the token representations are concatenated and fed into a softmax layer for relation classification. We evaluate our model on two standard benchmark datasets in different domains, namely Sem Eval-2010 Task 8 and Bio NLP-ST 2016 Task BB3. In Sem Eval-2010 Task 8, the performance of our model matches those of the state-of-the-art models, achieving 83.0% in F1. In Bio NLP-ST 2016 Task BB3, our model obtains F_1 51.3% which is comparable with that of the best system. Moreover, we find that the context between two target entities plays an important role in relation classification and it can be a replacement of the shortest dependency path. | REN Yuanfang TENG Chong LI Fei CHEN Bo JI Donghong | 2017 | Wuhan University Journal of Natural Sciences2017，22，6： | 6 |
| 14 | Molecular Characterization of Avian-like H1N1 Swine Influenza A Viruses Isolated in Eastern China, 2011显示文摘Currently, three predominant subtypes of influenza virus are prevalent in pig populations worldwide: H1N1, H3N2, and H1N2. European avian-like H1N1 viruses, which were initially detected in European pig populations in 1979, have been circulating in pigs in eastern China since 2007. In this study, six influenza A viruses were isolated from 60 swine lung samples collected from January to April 2011 in eastern China. Based on whole genome sequencing, molecular characteristics of two isolates were determined. Phylogenetic analysis showed the eight genes of the two isolates were closely related to those of the avian-like H1N1 viruses circulating in pig populations, especially similar to those found in China. Four potential glycosylation sites were observed at positions 13, 26, 198, 277 in the HA1 proteins of the two isolates. Due to the presence of a stop codon at codon 12, the isolates contained truncated PB1-F2 proteins. In this study, the isolates contained 591Q, 627E and 701N in the polymerase subunit PB2, which had been shown to be determinants of virulence and host adaptation. The isolates also had a D rather than E at position 92 of the NS1, a marker of mammalian adaptation. Both isolates contained the GPKV motif at the PDZ ligand domain of the 3' end of the NS1, a characteristic marker of the European avian-like swine viruses since about 1999, which is distinct from those of avian, human and classical swine viruses. The M2 proteins of the isolates have the mutation (S31N), a characteristic marker of the European avian-like swine viruses since about 1987, which may confer resistance to amantadine and rimantadine antivirals. Our findings further emphasize the importance of surveillance on the genetic diversity of influenza A viruses in pigs, and raise more concerns about the occurrence of cross-species transmission events. | Xian Qi Yuning Pan Yuanfang Qin Rongqiang Zu Fengyang Tang Minghao Zhou Hua Wang Yongchun Song | 2012 | Virologica Sinica2012，27，5： | 6 |
| 15 | Indole-3-propionic Acid-aggravated CCl_(4)-induced Liver Fibrosis via the TGF-β1/Smads Signaling Pathway显示文摘Background and Aims:The pathogenesis of liver fibrosis involves liver damage,inflammation,oxidative stress,and intestinal dysfunction.Indole-3-propionic acid(IPA)has been demonstrated to have antioxidant,anti-inflammatory and anticancer activities,and a role in maintaining gut homeostasis.The current study aimed to investigate the role of IPA in carbon tetrachloride(CCl4)-induced liver fibrosis and explore the underlying mechanisms.Methods:The liver fibrosis model was established in male C57BL/6 mice by intraperitoneal injection of CCl4 twice weekly.IPA intervention was made orally(20 mg/kg daily).The degree of liver injury and fibrosis were assessed by serum alanine aminotransferase(ALT),aspartate aminotransferase(AST),and histopathology.Enzyme-linked immunosorbent assay and quantitative real-time polymerase chain reaction(qPCR)were used to detect the inflammatory cytokines.The malondialdehyde(MDA),glutathione,glutathione peroxidase,superoxide dismutase,and catalase were determined via commercial kits.Hepatocyte apoptosis was detected by terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling assay.The expression of mRNA and protein was assayed by qPCR,Western blotting,or immunohistochemical staining.Results:After IPA treatment,the ALT and AST,apoptotic cells,and pro-inflammatory factor levels were enhanced significantly.Moreover,IPA intervention up-regulated the expression of collagen I,α-smooth muscle actin,tissue inhibitor of matrix metalloproteinase-1,matrix metalloproteinase-2,transforming growth factor-β1(TGF-β1),Smad3,and phosphorylated-Smad2/3.Additionally,IPA intervention did not affect the MDA level.Attractively,the administration of IPA remodeled the gut flora structure.Conclusions:IPA aggravated CCl_(4)-induced liver damage and fibrosis by activating HSCs via the TGF-β1/Smads signaling pathway. | Fei Liu Changfeng Sun Yuanfang Chen Fei Du Yuxiang Yang Gang Wu | 2021 | Journal of Clinical and Translational Hepatology2021，9，6： | 5 |
| 16 | The ostracod assemblages and their environmental significance in the Chen Co area, southern Tibet in recent 1400 years显示文摘The CC1 core, with a length of 216 cm, was drilled in the west part of the Chen Co (Lake) in southern Tibet Plateau. The 210Pb and 137Cs measurement indicated that it was a consecutive sedimentary sequence since ca. 1400 years. The ostracoda and their assemblages under the level of 1 cm samples’ cutting interval were finished for this core to reveal the past environmental changes in the lake area. A total of 15 species of ostracods belonging to 7 genera in the core sediments had been identified. According to the ostracod distributions, abundances and preservations in the core, seven ostracod assemblages had been distinguished. The ostracod assemblages and their ecological features, together with the sediments dating decision were used to infer the past ca. 1400 years environmental changes of the Chen Co environmental evolutions in three stages, which had responded to the Medieval Ages Warm-period (MAW), the Little Ice Age (LIA) and modern warm period. The results show that the changes of the Chen Co environment had been mainly influenced by the climatic variations. The trend of the lake level fluctuations had been accorded with that of climatic variation during the past 1400 years. | ZHU Liping, LI Yuanfang, LI Bingyuan(Inst. of Geographic Sciences and Natural Resources Research, CAS, Beijing 100101, China) | 2002 | Journal of Geographical Sciences2002，12，4： | 5 |
| 17 | A nomogram to predict prognosis for gastric cancer with peritoneal dissemination显示文摘Objective: To identify independent prognostic factors to be included in a nomogram to predict the prognosis of gastric cancer patients with peritoneal dissemination.Methods: This is a retrospective study on 684 patients with a histological diagnosis of gastric cancer with peritoneal dissemination from the Sun Yat-sen University Cancer Center as the development set, and 62 gastric cancer patients from the Sixth Affiliated Hospital of Sun Yat-sen University as the validation group. Chi-square test and Cox regression analysis were used to compare the clinicopathological variables and the prognosis of gastric cancer patients with peritoneal dissemination. The Harrell's concordance index(C-index) and calibration curve were determined for comparisons of predictive ability of the nomogram.Results: Univariate and multivariate analyses showed that serum carcinoembryonic antigen(CEA) level(P=0.032), ascites grading(P=0.008), presence of extraperitoneal metastasis(P<0.001), seeding status(P=0.016) and performance status(P=0.009) were independent prognostic factors for gastric cancer patients with peritoneal dissemination in the development set. The nomogram model was constructed using these five factors. Internal validation showed that the C-index of the model was 0.641. For the external validation, the C-index of this model was 0.709.Conclusions: We developed and validated a nomogram to predict the prognosis for gastric cancer patients with peritoneal dissemination. This nomogram may play an important clinical role in guiding palliative therapy for these types of patients, although it may need more data for optimization. | Shi Chen Xijie Chen Runcong Nie Liying Ou Yang Aihong Liu Yuanfang Li Zhiwei Zhou Yingbo Chen Junsheng Peng | 2018 | Chinese Journal of Cancer Research2018，30，4： | 5 |
| 18 | Mapping Soil Electrical Conductivity Using Ordinary Kriging Combined with Back-propagation Network显示文摘Accurate mapping of soil salinity and recognition of its influencing factors are essential for sustainable crop production and soil health. Although the influencing factors have been used to improve the mapping accuracy of soil salinity, few studies have considered both aspects of spatial variation caused by the influencing factors and spatial autocorrelations for mapping. The objective of this study was to demonstrate that the ordinary kriging combined with back-propagation network(OK_BP), considering the two aspects of spatial variation, which can benefit the improvement of the mapping accuracy of soil salinity. To test the effectiveness of this approach, 70 sites were sampled at two depths(0–30 and 30–50 cm) in Ningxia Hui Autonomous Region, China. Ordinary kriging(OK), back-propagation network(BP) and regression kriging(RK) were used in comparison analysis; the root mean square error(RMSE), relative improvement(RI) and the decrease in estimation imprecision(DIP) were used to judge the mapping quality. Results showed that OK_BP avoided the both underestimation and overestimation of the higher and lower values of interpolation surfaces. OK_BP revealed more details of the spatial variation responding to influencing factors, and provided more flexibility for incorporating various correlated factors in the mapping. Moreover, OK_BP obtained better results with respect to the reference methods(i.e., OK, BP, and RK) in terms of the lowest RMSE, the highest RI and DIP. Thus, it is concluded that OK_BP is an effective method for mapping soil salinity with a high accuracy. | HUANG Yajie LI Zhen YE Huichun ZHANG Shiwen ZHUO Zhiqing XING An HUANG Yuanfang | 2019 | Chinese Geographical Science2019，29，2： | 5 |
| 19 | Far-red light: A regulator of plant morphology and photosynthetic capacity显示文摘Plant photosynthetic capacity directly determines crop yield. Light quality regulates photosynthetic capacity. This review discusses plant responses to far-red light from the phenotypic to the molecular level, focusing specifically on the improvement of photosynthetic capacity by adjustment of photosynthetic electron transport and the path of light energy. Far-red light can also regulate leaf angle and increase plant height and leaf area, via expression of associated genes, to capture more light energy.Thus, far-red light regulates plant morphology and photosynthetic capacity. Identifying the mechanism of this regulation may lead to increased crop yields. | Tingting Tan Shenglan Li Yuanfang Fan Zhonglin Wang Muhammad Ali Raza Iram Shafiq Beibei Wang Xiaoling Wu Taiwen Yong Xiaochun Wang Yushan Wu Feng Yang Wenyu Yang | 2022 | The Crop Journal2022，10，2： | 4 |
| 20 | The Roles of Countrywomen in Controlling Non-point Source Pollution显示文摘The main causes of non-point source pollution in Taihu Lake are the improper ways of crop production, animal husbandry, and daily runoff. The paper discusses the relationship between countrywomen and non-point source pollution control by 731 questionnaires in Weidu village and 466 questionnaires in Dapu Town. The roles of countrywomen have changed in families and they have close relationship with non-point source pollution. Furthermore, we discuss the possibility and methods of organizing countrywomen in non-point source pollution control. | Jiang Dongmei Zhou Yuanfang Lu Genfa | 2006 | Chinese Journal of Population,Resources and Environment2006，4，2： | 4 |
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